Tom Huxford to I-kappa B Kinase
This is a "connection" page, showing publications Tom Huxford has written about I-kappa B Kinase.
Connection Strength
2.896
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Ko MS, Biswas T, Mulero MC, Bobkov AA, Ghosh G, Huxford T. Structurally plastic NEMO and oligomerization prone IKK2 subunits define the behavior of human IKK2:NEMO complexes in solution. Biochim Biophys Acta Proteins Proteom. 2020 12; 1868(12):140526.
Score: 0.719
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Hauenstein AV, Rogers WE, Shaul JD, Huang DB, Ghosh G, Huxford T. Probing kinase activation and substrate specificity with an engineered monomeric IKK2. Biochemistry. 2014 Apr 01; 53(12):2064-73.
Score: 0.460
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Polley S, Huang DB, Hauenstein AV, Fusco AJ, Zhong X, Vu D, Schr?felbauer B, Kim Y, Hoffmann A, Verma IM, Ghosh G, Huxford T. A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. PLoS Biol. 2013; 11(6):e1001581.
Score: 0.436
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Huxford T, Hoffmann A, Ghosh G. Understanding the logic of I?B:NF-?B regulation in structural terms. Curr Top Microbiol Immunol. 2011; 349:1-24.
Score: 0.369
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Shaul JD, Farina A, Huxford T. The human IKKbeta subunit kinase domain displays CK2-like phosphorylation specificity. Biochem Biophys Res Commun. 2008 Sep 26; 374(3):592-7.
Score: 0.311
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Ko MS, Cohen SN, Polley S, Mahata SK, Biswas T, Huxford T, Ghosh G. Regulatory subunit NEMO promotes polyubiquitin-dependent induction of NF-?B through a targetable second interaction with upstream activator IKK2. J Biol Chem. 2022 05; 298(5):101864.
Score: 0.201
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Napoleon JV, Singh S, Rana S, Bendjennat M, Kumar V, Kizhake S, Palermo NY, Ouellette MM, Huxford T, Natarajan A. Small molecule binding to inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner. Chem Commun (Camb). 2021 May 11; 57(38):4678-4681.
Score: 0.189
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Mulero MC, Huxford T, Ghosh G. NF-?B, I?B, and IKK: Integral Components of Immune System Signaling. Adv Exp Med Biol. 2019; 1172:207-226.
Score: 0.160
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Rana S, Kour S, Kizhake S, King HM, Mallareddy JR, Case AJ, Huxford T, Natarajan A. Dimers of isatin derived a-methylene-?-butyrolactone as potent anti-cancer agents. Bioorg Med Chem Lett. 2022 06 01; 65:128713.
Score: 0.050