Tom Huxford to Protein Binding
This is a "connection" page, showing publications Tom Huxford has written about Protein Binding.
Connection Strength
1.299
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Zhu N, Rogers WE, Heidary DK, Huxford T. Structural and biochemical analyses of the nuclear I?B? protein in complex with the NF-?B p50 homodimer. Genes Dev. 2024 Jul 19; 38(11-12):528-535.
Score: 0.677
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Ko MS, Biswas T, Mulero MC, Bobkov AA, Ghosh G, Huxford T. Structurally plastic NEMO and oligomerization prone IKK2 subunits define the behavior of human IKK2:NEMO complexes in solution. Biochim Biophys Acta Proteins Proteom. 2020 12; 1868(12):140526.
Score: 0.129
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Hauenstein AV, Rogers WE, Shaul JD, Huang DB, Ghosh G, Huxford T. Probing kinase activation and substrate specificity with an engineered monomeric IKK2. Biochemistry. 2014 Apr 01; 53(12):2064-73.
Score: 0.083
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Polley S, Huang DB, Hauenstein AV, Fusco AJ, Zhong X, Vu D, Schr?felbauer B, Kim Y, Hoffmann A, Verma IM, Ghosh G, Huxford T. A structural basis for I?B kinase 2 activation via oligomerization-dependent trans auto-phosphorylation. PLoS Biol. 2013; 11(6):e1001581.
Score: 0.078
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Fleming JK, Wojciak JM, Campbell MA, Huxford T. Biochemical and structural characterization of lysophosphatidic Acid binding by a humanized monoclonal antibody. J Mol Biol. 2011 May 06; 408(3):462-76.
Score: 0.067
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Huxford T, Ghosh G. A structural guide to proteins of the NF-kappaB signaling module. Cold Spring Harb Perspect Biol. 2009 Sep; 1(3):a000075.
Score: 0.060
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Maniaci B, Mealka M, Bobkov AA, Stec B, Huxford T, Love JJ. Incorporating Metal-Ligand and Salt-Bridge Interactions in the Design of Protein Heterodimers. Biochemistry. 2025 Aug 05; 64(15):3237-3247.
Score: 0.045
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Suryajaya W, Biswas T, Shahabi S, Mealka M, Huxford T, Ghosh G. HDX-MS Analysis of Catalytic Activation of IKK2 in the I?B Kinase Complex. Biochemistry. 2024 09 17; 63(18):2323-2334.
Score: 0.043
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Ko MS, Cohen SN, Polley S, Mahata SK, Biswas T, Huxford T, Ghosh G. Regulatory subunit NEMO promotes polyubiquitin-dependent induction of NF-?B through a targetable second interaction with upstream activator IKK2. J Biol Chem. 2022 05; 298(5):101864.
Score: 0.036
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Maniaci B, Lipper CH, Anipindi DL, Erlandsen H, Cole JL, Stec B, Huxford T, Love JJ. Design of High-Affinity Metal-Controlled Protein Dimers. Biochemistry. 2019 04 30; 58(17):2199-2207.
Score: 0.029
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Mulero MC, Shahabi S, Ko MS, Schiffer JM, Huang DB, Wang VY, Amaro RE, Huxford T, Ghosh G. Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor ?B RelA Subunit. Biochemistry. 2018 05 22; 57(20):2943-2957.
Score: 0.028
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Bergqvist S, Croy CH, Kjaergaard M, Huxford T, Ghosh G, Komives EA. Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex. J Mol Biol. 2006 Jul 07; 360(2):421-34.
Score: 0.012
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Hansen SB, Sulzenbacher G, Huxford T, Marchot P, Bourne Y, Taylor P. Structural characterization of agonist and antagonist-bound acetylcholine-binding protein from Aplysia californica. J Mol Neurosci. 2006; 30(1-2):101-2.
Score: 0.012