An attenuated Machupo virus with a disrupted L-segment intergenic region protects guinea pigs against lethal Guanarito virus infection.

Golden JW, Beitzel B, Ladner JT, Mucker EM, Kwilas SA, Palacios G, Hooper JW. An attenuated Machupo virus with a disrupted L-segment intergenic region protects guinea pigs against lethal Guanarito virus infection. Sci Rep. 2017 07 05; 7(1):4679.

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subject areas

Animals
Arenaviridae Infections
Arenaviruses, New World
Cell Line
Disease Models, Animal
DNA, Intergenic
Female
Guinea Pigs
Humans
Point Mutation
RNA, Viral
Sequence Analysis, RNA
Sequence Deletion
Vaccines, Attenuated
Vero Cells
Virulence Factors

authors with profiles

Jason Ladner

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