Squalamine blocks tumor-associated angiogenesis and growth of human breast cancer cells with or without HER-2/neu overexpression.

M?rquez-Garb?n DC, Gorr?n-Rivas M, Chen HW, Sterling C, Elashoff D, Hamilton N, Pietras RJ. Squalamine blocks tumor-associated angiogenesis and growth of human breast cancer cells with or without HER-2/neu overexpression. Cancer Lett. 2019 05 01; 449:66-75.

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subject areas

Angiogenesis Inhibitors
Animals
Breast Neoplasms
Cell Proliferation
Cholestanols
Female
Focal Adhesion Kinase 1
Gene Expression Regulation, Neoplastic
Humans
Mice
Phosphorylation
Receptor, erbB-2
Signal Transduction
Vascular Endothelial Growth Factor A
Xenograft Model Antitumor Assays

authors with profiles

Richard J. Pietras, MD, PhD

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