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Axel Lehrer

TitleAssistant Professor
InstitutionUniversity of Hawaii
DepartmentTropical Medicine
Address651 Ilalo Street, BSB320B
Honolulu HI 96813
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    Collapse Research 
    Collapse research activities and funding
    R43AI055225     (LEHRER, AXEL T)Jul 1, 2004 - Mar 31, 2007
    Recombinant Subunit Vaccine for Tick-Borne Encephalitis
    Role: Principal Investigator

    R43AI066616     (LEHRER, AXEL T)Jun 15, 2007 - Nov 30, 2009
    Development of a Recombinant Subunit Ebola Vaccine
    Role: Principal Investigator

    R01AI119185     (LEHRER, AXEL T)Aug 28, 2015 - Jul 31, 2019
    Defining a Protective Ebola Vaccine in Non-Human Primates
    Role: Principal Investigator

    R01AI132323     (LEHRER, AXEL T)Jun 20, 2017 - May 31, 2022
    Preclinical Development of a Thermostable Trivalent Filovirus Vaccine
    Role: Principal Investigator

    U01GH002256     (LEHRER, AXEL T)Sep 30, 2019 - Sep 29, 2024
    Epidemiology and Immunity to Ebola Virus and Other Emerging Viral Infections in Liberia
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Haun BK, Lai CY, Williams CA, Wong TA, Lieberman MM, Pessaint L, Andersen-Elyard H, Lehrer AT. CoVaccine HT™ adjuvant potentiates robust immune responses to recombinant SARS-CoV-2 Spike S1 immunisation. bioRxiv. 2020 Jul 26. PMID: 32743582.
    2. Tyson J, Tsai WY, Tsai JJ, Mässgård L, Stramer SL, Lehrer AT, Nerurkar VR, Wang WK. A high-throughput and multiplex microsphere immunoassay based on non-structural protein 1 can discriminate three flavivirus infections. PLoS Negl Trop Dis. 2019 08; 13(8):e0007649. PMID: 31442225.
      Citations: 1     Fields:    Translation:Humans
    3. Haun BK, Kamara V, Dweh AS, Garalde-Machida K, Forkay SSE, Takaaze M, Namekar M, Wong TAS, Bell-Gam Woto AER, Humphreys P, Weeks OI, Fallah MP, Berestecky JM, Nerurkar VR, Lehrer AT. Serological evidence of Ebola virus exposure in dogs from affected communities in Liberia: A preliminary report. PLoS Negl Trop Dis. 2019 07; 13(7):e0007614. PMID: 31329600.
      Citations:    Fields:    Translation:AnimalsCells
    4. Lehrer AT, Wong TS, Lieberman MM, Johns L, Medina L, Feldmann F, Feldmann H, Marzi A. Recombinant subunit vaccines protect guinea pigs from lethal Ebola virus challenge. Vaccine. 2019 11 08; 37(47):6942-6950. PMID: 31324500.
      Citations:    Fields:    
    5. Chisholm CF, Kang TJ, Dong M, Lewis K, Namekar M, Lehrer AT, Randolph TW. Thermostable Ebola virus vaccine formulations lyophilized in the presence of aluminum hydroxide. Eur J Pharm Biopharm. 2019 Mar; 136:213-220. PMID: 30703544.
      Citations: 1     Fields:    Translation:AnimalsCells
    6. Medina LO, To A, Lieberman MM, Wong TAS, Namekar M, Nakano E, Andersen H, Yalley-Ogunro J, Greenhouse J, Higgs S, Huang YS, Vanlandingham DL, Horton JS, Clements DE, Lehrer AT. A Recombinant Subunit Based Zika Virus Vaccine Is Efficacious in Non-human Primates. Front Immunol. 2018; 9:2464. PMID: 30467501.
      Citations: 1     Fields:    Translation:AnimalsCells
    7. To A, Medina LO, Mfuh KO, Lieberman MM, Wong TAS, Namekar M, Nakano E, Lai CY, Kumar M, Nerurkar VR, Lehrer AT. Recombinant Zika Virus Subunits Are Immunogenic and Efficacious in Mice. mSphere. 2018 Jan-Feb; 3(1). PMID: 29359186.
      Citations: 10     Fields:    
    8. Lai CY, Strange DP, Wong TAS, Lehrer AT, Verma S. Ebola Virus Glycoprotein Induces an Innate Immune Response In vivo via TLR4. Front Microbiol. 2017; 8:1571. PMID: 28861075.
    9. Lehrer AT, Wong TS, Lieberman MM, Humphreys T, Clements DE, Bakken RR, Hart MK, Pratt WD, Dye JM. Recombinant proteins of Zaire ebolavirus induce potent humoral and cellular immune responses and protect against live virus infection in mice. Vaccine. 2018 05 24; 36(22):3090-3100. PMID: 28216187.
      Citations: 9     Fields:    Translation:AnimalsCells
    10. Jiao GS, Kim S, Moayeri M, Crown D, Thai A, Cregar-Hernandez L, McKasson L, Sankaran B, Lehrer A, Wong T, Johns L, Margosiak SA, Leppla SH, Johnson AT. Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain. Bioorg Med Chem Lett. 2012 Mar 15; 22(6):2242-6. PMID: 22342144.
      Citations: 7     Fields:    Translation:AnimalsCells
    11. Pusic KM, Hashimoto CN, Lehrer A, Aniya C, Clements DE, Hui GS. T cell epitope regions of the P. falciparum MSP1-33 critically influence immune responses and in vitro efficacy of MSP1-42 vaccines. PLoS One. 2011; 6(9):e24782. PMID: 21931852.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    12. Cregar-Hernandez L, Jiao GS, Johnson AT, Lehrer AT, Wong TA, Margosiak SA. Small molecule pan-dengue and West Nile virus NS3 protease inhibitors. Antivir Chem Chemother. 2011 May 12; 21(5):209-17. PMID: 21566267.
      Citations: 11     Fields:    Translation:AnimalsCells
    13. Lehrer AT, Holbrook MR. Tick-borne Encephalitis Vaccines. J Bioterror Biodef. 2011; 2011(Suppl 1):3. PMID: 23997980.
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