RCMI Coordinating Center (RCMI CC) Header Logo

Xinbin Gu

Faculty RankProfessor
InstitutionHoward University
DepartmentOral Pathology
Address600 W Street, NW.
Room 210
Washington DC 20059
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    P20CA118770     (GU, XINBIN)Sep 30, 2005 - Aug 31, 2010
    HU/JHU Head and Neck Cancer Translational Research and *
    Role: Principal Investigator

    R15DE025138     (SHAN, LIANG)Aug 15, 2015 - Jul 31, 2019
    Humanized EGFR and EGFRvlll-bispecific Immunotoxin for HNSCC Therapy
    Role: Co-Principal Investigator

    R25DE025778     (GU, XINBIN)Jan 1, 2016 - Dec 31, 2020
    Howard University Summer Research Experience Program in Oral Health Disparity for Underrepresented Racial and Ethnic Students
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Liu M, Kao D, Gu X, Holland W, Cherry-Peppers G. Oral Health Service Access in Racial/Ethnic Minority Neighborhoods: A Geospatial Analysis in Washington, DC, USA. Int J Environ Res Public Health. 2022 04 20; 19(9). PMID: 35564382.
      Citations:    Fields:    Translation:Humans
    2. Xie G, Gu X. Bidirectional CART.BiTE cells bring new hope. Nat Rev Cancer. 2022 Apr; 22(4):194. PMID: 35110731.
      Citations:    Fields:    
    3. Xie G, Zhu A, Gu X. Converged DNA Damage Response Renders Human Hepatocellular Carcinoma Sensitive to CDK7 Inhibition. Cancers (Basel). 2022 Mar 28; 14(7). PMID: 35406486.
    4. Xie G, Shan L, Liu Y, Wu TC, Gu X. Antitumor Efficacy of EGFR-Targeted Recombinant Immunotoxin in Human Head and Neck Squamous Cell Carcinoma. Biology (Basel). 2022 Mar 22; 11(4). PMID: 35453686.
    5. Xie G, Zhu A, Gu X. Mitogen-activated protein kinase inhibition-induced modulation of epidermal growth factor receptor signaling in human head and neck squamous cell carcinoma. Head Neck. 2021 06; 43(6):1721-1729. PMID: 33533173.
      Citations: 3     Fields:    Translation:HumansCells
    6. Lin X, Sajith AM, Wang S, Kumari N, Choy MS, Ahmad A, Cadet DR, Gu X, Ivanov AI, Peti W, Kulkarni A, Nekhai S. Structural Optimization of 2,3-Dihydro-1H-cyclopenta[b]quinolines Targeting the Noncatalytic RVxF Site of Protein Phosphatase 1 for HIV-1 Inhibition. ACS Infect Dis. 2020 12 11; 6(12):3190-3211. PMID: 33258581.
      Citations: 2     Fields:    Translation:HumansCells
    7. Wan S, Cao S, Wang X, Zhou Y, Yan W, Gu X, Wu TC, Pang X. Generation and preliminary characterization of vertebrate-specific replication-defective Zika virus. Virology. 2021 01 02; 552:73-82. PMID: 33075709.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    8. Sha W, Zhou Y, Ling ZQ, Xie G, Pang X, Wang P, Gu X. Antitumor properties of Salvianolic acid B against triple-negative and hormone receptor-positive breast cancer cells via ceramide-mediated apoptosis. Oncotarget. 2018 Nov 20; 9(91):36331-36343. PMID: 30555632.
      Citations: 14     Fields:    
    9. Zhu S, Liu Y, Wang PC, Gu X, Shan L. Recombinant Immunotoxin Therapy of Glioblastoma: Smart Design, Key Findings, and Specific Challenges. Biomed Res Int. 2017; 2017:7929286. PMID: 28752098.
      Citations: 5     Fields:    Translation:HumansAnimals
    10. Zhao Y, Ling Z, Hao Y, Pang X, Han X, Califano JA, Shan L, Gu X. MiR-124 acts as a tumor suppressor by inhibiting the expression of sphingosine kinase 1 and its downstream signaling in head and neck squamous cell carcinoma. Oncotarget. 2017 Apr 11; 8(15):25005-25020. PMID: 28212569.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    11. Zhu A, Guan X, Gu X, Xie G. Probe-free allele-specific copy number detection and analysis of tumors. Anal Biochem. 2016 Mar 15; 497:95-102. PMID: 26743720.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    12. Hauser B, Zhao Y, Pang X, Ling Z, Myers E, Wang P, Califano J, Gu X. Functions of MiRNA-128 on the regulation of head and neck squamous cell carcinoma growth and apoptosis. PLoS One. 2015; 10(3):e0116321. PMID: 25764126.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    13. Meng J, Liu Y, Gao S, Lin S, Gu X, Pomper MG, Wang PC, Shan L. A bivalent recombinant immunotoxin with high potency against tumors with EGFR and EGFRvIII expression. Cancer Biol Ther. 2015; 16(12):1764-74. PMID: 26467217.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    14. Pang X, Guo Y, Zhou Y, Fu W, Gu X. Highly efficient production of a dengue pseudoinfectious virus. Vaccine. 2014 Jun 24; 32(30):3854-60. PMID: 24797700.
      Citations: 4     Fields:    Translation:AnimalsCells
    15. Zhou Y, Sridhar R, Shan L, Sha W, Gu X, Sukumar S. Loperamide, an FDA-approved antidiarrhea drug, effectively reverses the resistance of multidrug resistant MCF-7/MDR1 human breast cancer cells to doxorubicin-induced cytotoxicity. Cancer Invest. 2012 Feb; 30(2):119-25. PMID: 22250587.
      Citations: 12     Fields:    Translation:HumansCells
    16. Hao Y, Gu X, Zhao Y, Greene S, Sha W, Smoot DT, Califano J, Wu TC, Pang X. Enforced expression of miR-101 inhibits prostate cancer cell growth by modulating the COX-2 pathway in vivo. Cancer Prev Res (Phila). 2011 Jul; 4(7):1073-83. PMID: 21430074.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    17. Hao Y, Zhao Y, Zhao X, He C, Pang X, Wu TC, Califano JA, Gu X. Improvement of prostate cancer detection by integrating the PSA test with miRNA expression profiling. Cancer Invest. 2011 May; 29(4):318-24. PMID: 21345070.
      Citations: 20     Fields:    Translation:HumansCells
    18. Zhao Y, Guo Y, Gu X. Salvianolic Acid B, a potential chemopreventive agent, for head and neck squamous cell cancer. J Oncol. 2011; 2011:534548. PMID: 21209716.
    19. Zhao Y, Hao Y, Ji H, Fang Y, Guo Y, Sha W, Zhou Y, Pang X, Southerland WM, Califano JA, Gu X. Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo. Cancer Prev Res (Phila). 2010 Jun; 3(6):787-96. PMID: 20501859.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    20. Hao Y, Xie T, Korotcov A, Zhou Y, Pang X, Shan L, Ji H, Sridhar R, Wang P, Califano J, Gu X. Salvianolic acid B inhibits growth of head and neck squamous cell carcinoma in vitro and in vivo via cyclooxygenase-2 and apoptotic pathways. Int J Cancer. 2009 May 01; 124(9):2200-9. PMID: 19123475.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    21. Gu X, Song X, Dong Y, Cai H, Walters E, Zhang R, Pang X, Xie T, Guo Y, Sridhar R, Califano JA. Vitamin E succinate induces ceramide-mediated apoptosis in head and neck squamous cell carcinoma in vitro and in vivo. Clin Cancer Res. 2008 Mar 15; 14(6):1840-8. PMID: 18347187.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    22. Shan L, Hao Y, Wang S, Korotcov A, Zhang R, Wang T, Califano J, Gu X, Sridhar R, Bhujwalla ZM, Wang PC. Visualizing head and neck tumors in vivo using near-infrared fluorescent transferrin conjugate. Mol Imaging. 2008 Jan-Feb; 7(1):42-9. PMID: 18384723.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    23. Zhou Y, Gu X, Ashayeri E, Zhang R, Sridhar R. Nicotine decreases the cytotoxicity of doxorubicin towards MCF-7 and KB-3.1 human cancer cells in culture. J Natl Med Assoc. 2007 Apr; 99(4):319-27. PMID: 17444420.
      Citations: 6     Fields:    Translation:HumansPHPublic Health
    24. Gu X, Schwartz JL, Pang X, Zhou Y, Sirois DA, Sridhar R. Cytotoxicity of liposomal alpha-tocopheryl succinate towards hamster cheek pouch carcinoma (HCPC-1) cells in culture. Cancer Lett. 2006 Aug 08; 239(2):281-91. PMID: 16271438.
      Citations:    Fields:    Translation:AnimalsCells
    Gu's Networks
    Click the
    buttons for more information and interactive visualizations!
    Concepts (151)
    Co-Authors (8)
    Similar People (60)
    RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

    For technical support please contact support