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George Perry

TitleDr.
InstitutionUniversity of Texas at San Antonio
DepartmentCollege of Sciences
AddressCollege of Sciences
One UTSA Circle
San Antonio TX 78249
Phone(210) 458-8660
Fax(210) 458-5658
ORCID ORCID Icon0000-0002-6547-0172 Additional info
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    Other Positions
    TitleAffiliate Professor
    InstitutionUniversity of Alaska Fairbanks
    DepartmentChemistry and Biochemistry


    Collapse Biography 
    Collapse awards and honors
    2001Distinguished American of Portuguese Ancestry, Portuguese-American Historical and Research Foundation
    2003Hall of Fame, Lompoc High School Alumni Association
    2003Mensch Award , Alzheimer Research Forum
    2003Top 20 Most-Cited Authors in Alzheimer’s Disease, Essential Science Indicators
    2004 - 2007100 Most-Cited Scientists in Neuroscience and Behavior of the Decade, In-cites
    2004Community Service Award, Cleveland Area Chapter of the Alzheimer’s Association
    2007Doctorado Honoris Causa (Hon. D.) , Universidad Arturo Prat, Iquique, Chile
    2007Top 25 Lab Heads in Free Radical Research, Free Radical Lab Registry
    2007Zenith Fellow, Alzheimer’s Association
    2008Denham Harman Research Award, American Aging Association
    2008ISI Highly Cited.com, Neuroscience
    2009Foreign Corresponding Member, Royal Spanish Academy of Sciences
    2009Top 100 Alzheimer’s Disease Investigators
    2010Alzheimer Award / Alzheimer Medal, Journal of Alzheimer’s Disease
    2010Corresponding Member, Mexican Academy of Sciences
    2010Distinguished Professional Mentor Award, Society for the Advancement of Chicanos and Native American Scientists (SACNAS)
    2011Alzheimer Award / Alzheimer Medal, Journal of Alzheimer’s Disease
    2011Chartered Biologist (CBiol), Society of Biology
    2011Fellow, Linnean Society of London
    2011Fellow, Microscopy Society of America
    2011Fellow, Royal College of Pathologists
    2011Fellow, Royal Society of Biology
    2011Fellow, Royal Society of Chemistry
    2011Foreign Corresponding Member, Academy of Sciences of Lisbon
    2011National Honor Plaque of Panama for Exceptional Contribution to “Neuroscience", Secretar?a nacional de Ciencia, Technolog?a e Innovación (SENACYT)
    2011Senior Investigator Award, International College of Geriatric Psychoneuropharmacology (ICGP)
    2011Top 20 Alzheimer’s Disease Authors,
    2012Charter and Life Member, Phi Kappa Phi
    2012Chartered Chemist (CChem), Royal Society of Chemistry
    2012Chartered Scientist (CSci), Royal Society of Biology
    2012Fulbright Senior Scholar Specialist Program, US Deparment of State
    2012Gente Notavel(Notable People), Azorean Spirit, SATA Inflight Magazine
    2012Notaveis dos Azores, Governo dos Azores
    2012Outstanding Service Award, International Conference on Research in Applied Computation Symposium
    2012Scientist of the Year, Portuguese Tribune
    2013Distinguished Chair in Neurobiology, Semmes Foundation
    2013Leading Expert-Alzheimer Disease, Expertscape
    2013Martin Goland Award, Sigma XI, Alamo Chapter
    2014Fellow, Royal Microscopical Society, (FRMS)
    2014Fellow, Royal Society of the Encouragement of Arts, Manufactures and Commerce
    2014UDAAN-Lifetime Achievement Award, International Journal of Humanities, Engineering and Pharmaceutical Sciences..., India
    2015Distinguished Fellow and President, International Engineering and Technology Institute
    2015Fellow, Association of Biotechnology and Pharmacy (India), FABAP
    2016Fellow, Texas Academy of Sciences
    2016Lifetime Achievement, World Automation Congress
    2016Semmes Distinguished University Chair in Neurobiology, Semmes Foundation
    2017Albert Nelson Marquis Lifetime Achievement Award, Marquis Who''s Who
    2017Annual Scientific Award, International Engineering and Technology Institute
    2017Chartered Science Teacher (CSciTeach), Royal Society of Biology
    2017Fellow, World Academy of Medical Sciences
    2017Member, EU Academy of Sciences
    2017Who's Who Lifetime Achievement, Marquis Who’s Who
    2018Counselors, Conselho da Diáspora Portuguesa
    2018Distinction of Excellence Award in Alzheimer''s Disease Research, Alzheimer Association:
    2018Honorable Director, Global Listening Centre
    2020Texas Distinguished Scientist, Texas Academy of Sciences
    2021Rous-Whipple Award, American Society for Investigative Pathology

    Collapse Overview 
    Collapse overview
    George Perry is former dean of the College of Sciences and the Semmes Foundation Distinguished University Chair in Neurobiology at The University of Texas at San Antonio. Dr. Perry is recognized in the field of Alzheimer’s disease research particularly for his work on oxidative metabolism.

    Dr. Perry is distinguished as one of the top Alzheimer’s disease researchers with over 1,000 publications, and one of the top 100 most-cited scientists in neuroscience and behavior (Over 96,000 citations, H=155), as well as the Expertscape Leading Expert in Alzheimer’s disease. Perry serves as editor for numerous journals and is editor-in-chief for the Journal of Alzheimer's Disease. He is a fellow of the American Association for the Advancement of Sciences, International Engineering and Technology Institute, Texas Academy of Sciences, and Microscopy Society of America, a Fulbright Senior Specialist, as well as a member of the Dana Alliance for Brain Initiatives. Perry is also recognized internationally: he is a Foreign Member of the Spanish Royal Academy of Sciences, the Academy of Science Lisbon, and the Mexican National Academy of Sciences. He is also a recipient of the National Plaque of Honor from the Republic of Panama Ministry of Science and Technology.

    Dr. Perry received his BA in zoology from the University of California, Santa Barbara followed by his Ph.D. in Marine Biology from Scripps Institution of Oceanography. He then received a postdoctoral fellowship in the Department of Cell Biology at Baylor College of Medicine where he laid the foundation for his observations of abnormalities in cell structures.

    Collapse Research 
    Collapse research activities and funding
    K04AG000415     (PERRY, GEORGE)Apr 1, 1988 - Aug 31, 1993
    NIH
    AMYLOID PRECURSOR IN ALZHEIMER DISEASE
    Role: Principal Investigator

    R01AG007552     (PERRY, GEORGE)Apr 1, 1988 - Mar 31, 1994
    NIH
    AMYLOID PRECURSOR IN ALZHEIMER DISEASE
    Role: Principal Investigator

    N01AI095039     (PEREZ, GEORGE)Sep 30, 1989 - Sep 29, 1994
    NIH
    COMMUNITY PROGRAMS FOR CLINICAL RESEARCH ON AIDS
    Role: Co-Investigator

    R01AG009287     (PERRY, GEORGE)Sep 1, 1990 - Nov 30, 2000
    NIH
    NEUROFIBRILLARY PATHOLOGY IN ALZHEIMER DISEASE
    Role: Principal Investigator

    G12RR013646     (TSIN, ANDREW T C)Sep 30, 1998 - Sep 29, 2003
    NIH
    RCMI Center for Interdiscplinary Health Research CIHR
    Role: Co-Investigator

    G12MD007591     (TSIN, ANDREW T C)Sep 30, 1998 - Jun 30, 2017
    NIH
    RCMI Center for Interdiscplinary Health Research CIHR
    Role: Co-Investigator

    F32GM085998     (PERRY, GEORGE HERBERT)Aug 11, 2008 - Aug 10, 2011
    NIH
    Studying the evolution of gene regulation at the protein level in primates
    Role: Principal Investigator

    R01GM115656     (PERRY, GEORGE HERBERT)Jun 20, 2016 - May 31, 2021
    NIH
    Hunter-gatherer vs. agriculturalist growth and immune system functional genomics
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Plascencia-Villa G, Perry G. Status and future directions of clinical trials in Alzheimer's disease. Int Rev Neurobiol. 2020; 154:3-50. PMID: 32739008.
      Citations:    
    2. Plascencia-Villa G, Perry G. Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis. Antioxid Redox Signal. 2020 Jul 17. PMID: 32486897.
      Citations:    Fields:    
    3. González-Sánchez M, Bartolome F, Antequera D, Puertas-Martín V, González P, Gómez-Grande A, Llamas-Velasco S, Herrero-San Martín A, Pérez-Martínez D, Villarejo-Galende A, Atienza M, Palomar-Bonet M, Cantero JL, Perry G, Orive G, Ibañez B, Bueno H, Fuster V, Carro E. Decreased salivary lactoferrin levels are specific to Alzheimer's disease. EBioMedicine. 2020 Jul; 57:102834. PMID: 32586758.
      Citations:    Fields:    
    4. Veurink G, Perry G, Singh SK. Role of antioxidants and a nutrient rich diet in Alzheimer's disease. Open Biol. 2020 06; 10(6):200084. PMID: 32543351.
      Citations:    Fields:    
    5. Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances. Mol Neurodegener. 2020 05 29; 15(1):30. PMID: 32471464.
      Citations: 1     Fields:    
    6. Obrenovich M, Jaworski H, Tadimalla T, Mistry A, Sykes L, Perry G, Bonomo RA. The Role of the Microbiota-Gut-Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases. Microorganisms. 2020 May 23; 8(5). PMID: 32456229.
      Citations:    
    7. Obrenovich M, Tabrez S, Siddiqui B, McCloskey B, Perry G. The Microbiota-Gut-Brain Axis-Heart Shunt Part II: Prosaic Foods and the Brain-Heart Connection in Alzheimer Disease. Microorganisms. 2020 Mar 31; 8(4). PMID: 32244373.
      Citations:    
    8. Perry GH. How human behavior can impact the evolution of genetically-mediated behavior in wild non-human species. J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2020 May; 206(3):337-342. PMID: 32201915.
      Citations:    Fields:    
    9. Yeung AWK, Tzvetkov NT, Georgieva MG, Ognyanov IV, Kordos K, Józwik A, Kühl T, Perry G, Petralia MC, Mazzon E, Atanasov AG. Reactive Oxygen Species and Their Impact in Neurodegenerative Diseases: Literature Landscape Analysis. Antioxid Redox Signal. 2020 Mar 09. PMID: 32030995.
      Citations:    Fields:    
    10. Grogan KE, Perry GH. Studying human and nonhuman primate evolutionary biology with powerful in vitro and in vivo functional genomics tools. Evol Anthropol. 2020 May; 29(3):143-158. PMID: 32142200.
      Citations:    Fields:    
    11. Reddy VP, Aryal P, Robinson S, Rafiu R, Obrenovich M, Perry G. Polyphenols in Alzheimer's Disease and in the Gut-Brain Axis. Microorganisms. 2020 Jan 31; 8(2). PMID: 32023969.
      Citations:    
    12. Reyes-Pablo AE, Campa-Córdoba BB, Luna-Viramontes NI, Ontiveros-Torres MÁ, Villanueva-Fierro I, Bravo-Muñoz M, Sáenz-Ibarra B, Barbosa O, Guadarrama-Ortíz P, Garcés-Ramírez L, de la Cruz F, Harrington CR, Martínez-Robles S, González-Ballesteros E, Perry G, Pacheco-Herrero M, Luna-Muñoz J. National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in México. J Alzheimers Dis. 2020; 76(3):853-862. PMID: 32568191.
      Citations:    Fields:    
    13. Hernandes-Alejandro M, Montaño S, Harrington CR, Wischik CM, Salas-Casas A, Cortes-Reynosa P, Pérez Salazar E, Cazares-Apatiga J, Apatiga-Perez R, Ontiveros Torres MÁ, Perry G, Pacheco-Herrero M, Luna-Muñoz J. Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease. J Alzheimers Dis. 2020; 76(2):553-569. PMID: 32538846.
      Citations:    Fields:    
    14. Perry G. Alzheimer's Disease Patients in the Crosshairs of COVID-19. J Alzheimers Dis. 2020; 76(1):1. PMID: 32623403.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    15. Iverson GL, Gardner AJ, Shultz SR, Solomon GS, McCrory P, Zafonte R, Perry G, Hazrati LN, Keene CD, Castellani RJ. Chronic traumatic encephalopathy neuropathology might not be inexorably progressive or unique to repetitive neurotrauma. Brain. 2019 Dec 01; 142(12):3672-3693. PMID: 31670780.
      Citations: 2     Fields:    Translation:Humans
    16. Gao J, Wang L, Gao C, Arakawa H, Perry G, Wang X. TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2020 01 01; 1866(1):165580. PMID: 31678156.
      Citations:    Fields:    Translation:AnimalsCells
    17. Aiello P, Consalvi S, Poce G, Raguzzini A, Toti E, Palmery M, Biava M, Bernardi M, Kamal MA, Perry G, Peluso I. Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy. Semin Cancer Biol. 2019 Aug 24. PMID: 31454670.
      Citations:    Fields:    
    18. Gao J, Wang L, Yan T, Perry G, Wang X. TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration. Mol Cell Neurosci. 2019 10; 100:103396. PMID: 31445085.
      Citations:    Fields:    Translation:HumansAnimalsCells
    19. Lopez M, Choin J, Sikora M, Siddle K, Harmant C, Costa HA, Silvert M, Mouguiama-Daouda P, Hombert JM, Froment A, Le Bomin S, Perry GH, Barreiro LB, Bustamante CD, Verdu P, Patin E, Quintana-Murci L. Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest. Curr Biol. 2019 09 09; 29(17):2926-2935.e4. PMID: 31402299.
      Citations: 1     Fields:    Translation:HumansCells
    20. Harrison GF, Sanz J, Boulais J, Mina MJ, Grenier JC, Leng Y, Dumaine A, Yotova V, Bergey CM, Nsobya SL, Elledge SJ, Schurr E, Quintana-Murci L, Perry GH, Barreiro LB. Natural selection contributed to immunological differences between hunter-gatherers and agriculturalists. Nat Ecol Evol. 2019 08; 3(8):1253-1264. PMID: 31358949.
      Citations: 1     Fields:    Translation:HumansCells
    21. Luca M, Di Mauro M, Perry G. Neuropsychiatric Disturbances and Diabetes Mellitus: The Role of Oxidative Stress. Oxid Med Cell Longev. 2019; 2019:5698132. PMID: 31354908.
      Citations:    Fields:    Translation:Humans
    22. Zavala EI, Rajagopal S, Perry GH, Kruzic I, Bašic Ž, Parsons TJ, Holland MM. Impact of DNA degradation on massively parallel sequencing-based autosomal STR, iiSNP, and mitochondrial DNA typing systems. Int J Legal Med. 2019 Sep; 133(5):1369-1380. PMID: 31267160.
      Citations:    Fields:    Translation:HumansCells
    23. Singh SK, Srivastav S, Castellani RJ, Plascencia-Villa G, Perry G. Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders. Neurotherapeutics. 2019 07; 16(3):666-674. PMID: 31376068.
      Citations: 4     Fields:    Translation:HumansAnimals
    24. Sena CM, Seiça R, Perry G. Editorial: Oxidative Stress Revisited-Major Role in Vascular Diseases. Front Physiol. 2019; 10:788. PMID: 31293452.
      Citations:    
    25. Perry GH, Makarewicz CA. Horse Paleogenomes and Human-Animal Interactions in Prehistory. Trends Genet. 2019 07; 35(7):473-475. PMID: 31109769.
      Citations:    Fields:    Translation:HumansAnimals
    26. Jones L, Kumar J, Mistry A, Sankar Chittoor Mana T, Perry G, Reddy VP, Obrenovich M. The Transformative Possibilities of the Microbiota and Mycobiota for Health, Disease, Aging, and Technological Innovation. Biomedicines. 2019 Mar 28; 7(2). PMID: 30925795.
      Citations:    
    27. Ofili EO, Tchounwou PB, Fernandez-Repollet E, Yanagihara R, Akintobi TH, Lee JE, Malouhi M, Garner ST, Hayes TT, Baker AR, Dent AL, Abdelrahim M, Rollins L, Chang SP, Sy A, Hernandez BY, Bullard PL, Noel RJ, Shiramizu B, Hedges JR, Berry MJ, Bond VC, Lima MF, Mokuau N, Kirken RA, Cruz-Correa M, Sarpong DF, Vadgama J, Yates C, Kahn SA, Soliman KF, Perry G, Pezzano M, Luciano CA, Barnett ME, Oyekan A, Kumar D, Norris KC. The Research Centers in Minority Institutions (RCMI) Translational Research Network: Building and Sustaining Capacity for Multi-Site Basic Biomedical, Clinical and Behavioral Research. Ethn Dis. 2019; 29(Suppl 1):135-144. PMID: 30906162.
      Citations:    Fields:    Translation:Humans
    28. Castellani RJ, Plascencia-Villa G, Perry G. The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation. Lab Invest. 2019 07; 99(7):958-970. PMID: 30760863.
      Citations: 3     Fields:    Translation:Humans
    29. Espay AJ, Vizcarra JA, Marsili L, Lang AE, Simon DK, Merola A, Josephs KA, Fasano A, Morgante F, Savica R, Greenamyre JT, Cambi F, Yamasaki TR, Tanner CM, Gan-Or Z, Litvan I, Mata IF, Zabetian CP, Brundin P, Fernandez HH, Standaert DG, Kauffman MA, Schwarzschild MA, Sardi SP, Sherer T, Perry G, Leverenz JB. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology. 2019 02 12; 92(7):329-337. PMID: 30745444.
      Citations: 7     Fields:    Translation:Humans
    30. Wang C, Zhao F, Shen K, Wang W, Siedlak SL, Lee HG, Phelix CF, Perry G, Shen L, Tang B, Yan R, Zhu X. The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease. Brain Pathol. 2019 07; 29(4):530-543. PMID: 30515907.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    31. Rodriguez RA, Liang H, Chen LY, Plascencia-Villa G, Perry G. Single-channel permeability and glycerol affinity of human aquaglyceroporin AQP3. Biochim Biophys Acta Biomembr. 2019 04 01; 1861(4):768-775. PMID: 30659792.
      Citations: 2     Fields:    Translation:HumansCells
    32. Castellani RJ, Perry G. Tau Biology, Tauopathy, Traumatic Brain Injury, and Diagnostic Challenges. J Alzheimers Dis. 2019; 67(2):447-467. PMID: 30584140.
      Citations:    Fields:    Translation:HumansAnimals
    33. Montero-Odasso M, Perry G. Gait Disorders in Alzheimer's Disease and Other Dementias: There is Something in the Way You Walk. J Alzheimers Dis. 2019; 71(s1):S1-S4. PMID: 31476163.
      Citations:    Fields:    
    34. Hampel H, Vergallo A, Perry G, Lista S. The Alzheimer Precision Medicine Initiative. J Alzheimers Dis. 2019; 68(1):1-24. PMID: 30814352.
      Citations:    Fields:    Translation:Humans
    35. Perry G. Preface. Mini Rev Med Chem. 2019; 19(1):2. PMID: 30626312.
      Citations:    Fields:    
    36. Tripathy A, Shade A, Erskine B, Bailey K, Grande A, deLong JJ, Perry G, Castellani RJ. No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study. J Alzheimers Dis. 2019; 67(4):1277-1289. PMID: 30741674.
      Citations: 2     Fields:    Translation:Humans
    37. Castellani RJ, Smith M, Bailey K, Perry G, deJong JL. Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury. J Alzheimers Dis. 2019; 72(3):683-691. PMID: 31609691.
      Citations:    Fields:    
    38. Hampel H, Lista S, Mango D, Nisticò R, Perry G, Avila J, Hernandez F, Geerts H, Vergallo A. Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective. J Alzheimers Dis. 2019; 69(3):615-629. PMID: 31156173.
      Citations: 1     Fields:    
    39. Liu M, Wang L, Gao J, Dong Q, Perry G, Ma X, Wang X. Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice. J Alzheimers Dis. 2019; 69(4):1077-1087. PMID: 31156179.
      Citations:    Fields:    
    40. Mohammadi A, Maleki-Jamshid A, Sanooghi D, Milan PB, Rahmani A, Sefat F, Shahpasand K, Soleimani M, Bakhtiari M, Belali R, Faghihi F, Joghataei MT, Perry G, Mozafari M. Correction to: Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders. Mol Neurobiol. 2019 Jan; 56(1):319-320. PMID: 29700773.
      Citations:    Fields:    
    41. Flores-Rodríguez P, Harrington CR, Wischik CM, Ibarra-Bracamontes V, Zarco N, Navarrete A, Martínez-Maldonado A, Guadarrama-Ortíz P, Villanueva-Fierro I, Ontiveros-Torres MA, Perry G, Alonso AD, Floran-Garduño B, Segovia J, Luna-Muñoz J. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study. J Alzheimers Dis. 2019; 71(2):631-645. PMID: 31424392.
      Citations:    Fields:    
    42. Sena CM, Leandro A, Azul L, Seiça R, Perry G. Vascular Oxidative Stress: Impact and Therapeutic Approaches. Front Physiol. 2018; 9:1668. PMID: 30564132.
      Citations:    
    43. Kelley AR, Bach SBH, Perry G. Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2040-2047. PMID: 30481587.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    44. Bergey CM, Lopez M, Harrison GF, Patin E, Cohen JA, Quintana-Murci L, Barreiro LB, Perry GH. Polygenic adaptation and convergent evolution on growth and cardiac genetic pathways in African and Asian rainforest hunter-gatherers. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):E11256-E11263. PMID: 30413626.
      Citations: 1     Fields:    Translation:Humans
    45. Pinho TS, Correia SC, Perry G, Ambrósio AF, Moreira PI. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2048-2059. PMID: 30412792.
      Citations:    Fields:    Translation:HumansAnimalsCells
    46. Peluso I, Palmery M, Yarla NS, Perry G, Kamal MA. From Oxidative Stress to Ageing via Lifestyle, Nutraceuticals, Polypharmacy, and Neuropsychological Factors. Oxid Med Cell Longev. 2018; 2018:6352689. PMID: 30363930.
      Citations:    Fields:    Translation:HumansAnimals
    47. Hernández F, Cuadros R, Ollá I, García C, Ferrer I, Perry G, Avila J. Differences in structure and function between human and murine tau. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2024-2030. PMID: 31189515.
      Citations:    Fields:    Translation:HumansAnimalsCells
    48. Wang L, Gao J, Liu J, Siedlak SL, Torres S, Fujioka H, Huntley ML, Jiang Y, Ji H, Yan T, Harland M, Termsarasab P, Zeng S, Jiang Z, Liang J, Perry G, Hoppel C, Zhang C, Li H, Wang X. Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles. Cell Metab. 2018 09 04; 28(3):400-414.e8. PMID: 30017354.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    49. Everett J, Collingwood JF, Tjendana-Tjhin V, Brooks J, Lermyte F, Plascencia-Villa G, Hands-Portman I, Dobson J, Perry G, Telling ND. Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects. Nanoscale. 2018 Jul 05; 10(25):11782-11796. PMID: 29688240.
      Citations: 6     Fields:    Translation:Humans
    50. Liang H, Bourdon AK, Chen LY, Phelix CF, Perry G. Gibbs Free-Energy Gradient along the Path of Glucose Transport through Human Glucose Transporter 3. ACS Chem Neurosci. 2018 11 21; 9(11):2815-2823. PMID: 29865792.
      Citations:    Fields:    Translation:HumansCells
    51. Mahmoudi M, Pakpour S, Perry G. Drug-Abuse Nanotechnology: Opportunities and Challenges. ACS Chem Neurosci. 2018 10 17; 9(10):2288-2298. PMID: 29851334.
      Citations:    Fields:    Translation:HumansPHPublic Health
    52. Mondragón-Rodríguez S, Salas-Gallardo A, González-Pereyra P, Macías M, Ordaz B, Peña-Ortega F, Aguilar-Vázquez A, Orta-Salazar E, Díaz-Cintra S, Perry G, Williams S. Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model. J Biol Chem. 2018 06 01; 293(22):8462-8472. PMID: 29632073.
      Citations: 3     Fields:    Translation:AnimalsCells
    53. Paley EL, Perry G. Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration. Nutrients. 2018 Mar 26; 10(4). PMID: 29587458.
      Citations:    Fields:    Translation:HumansAnimalsCells
    54. Mohammadi A, Maleki-Jamshid A, Sanooghi D, Milan PB, Rahmani A, Sefat F, Shahpasand K, Soleimani M, Bakhtiari M, Belali R, Faghihi F, Joghataei MT, Perry G, Mozafari M. Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders. Mol Neurobiol. 2019 Jan; 56(1):307-318. PMID: 29549645.
      Citations:    Fields:    Translation:HumansAnimalsCells
    55. Gao J, Wang L, Huntley ML, Perry G, Wang X. Pathomechanisms of TDP-43 in neurodegeneration. J Neurochem. 2018 Feb 27. PMID: 29486049.
      Citations: 3     Fields:    
    56. Hampel H, Vergallo A, Aguilar LF, Benda N, Broich K, Cuello AC, Cummings J, Dubois B, Federoff HJ, Fiandaca M, Genthon R, Haberkamp M, Karran E, Mapstone M, Perry G, Schneider LS, Welikovitch LA, Woodcock J, Baldacci F, Lista S. Precision pharmacology for Alzheimer's disease. Pharmacol Res. 2018 04; 130:331-365. PMID: 29458203.
      Citations: 5     Fields:    Translation:HumansAnimals
    57. Kelley AR, Colley ME, Perry G, Bach SBH. Incubation with Cu(II) and Zn(II) salts enhances MALDI-TOF mass spectra of amyloid-beta and a-synuclein toward in vivo analysis. J Mass Spectrom. 2018 Feb; 53(2):162-171. PMID: 29111606.
      Citations:    Fields:    Translation:HumansCells
    58. Jiang S, Nandy P, Wang W, Ma X, Hsia J, Wang C, Wang Z, Niu M, Siedlak SL, Torres S, Fujioka H, Xu Y, Lee HG, Perry G, Liu J, Zhu X. Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex. Mol Neurodegener. 2018 02 01; 13(1):5. PMID: 29391029.
      Citations: 4     Fields:    Translation:AnimalsCells
    59. Pérez-Ibave DC, Rodríguez-Sánchez IP, Garza-Rodríguez ML, Pérez-Maya AA, Luna M, Arámburo C, Tsin A, Perry G, Mohamed-Noriega K, Mohamed-Noriega J, Cavazos-Adame H, Mohamed-Hamsho J, Barrera-Saldaña HA. Expression of growth hormone gene in the baboon eye. Exp Eye Res. 2018 04; 169:157-169. PMID: 29407222.
      Citations:    Fields:    Translation:HumansAnimals
    60. Plascencia-Villa G, Perry G. Iron·ic facts about dementia. J Neurol Neurosurg Psychiatry. 2018 05; 89(5):446-447. PMID: 29353235.
      Citations:    Fields:    Translation:Humans
    61. Kelley AR, Perry G, Bach SBH. Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer's Diseased Brains by MALDI-TOF MS with MS/MS. ACS Chem Neurosci. 2018 04 18; 9(4):708-714. PMID: 29301075.
      Citations:    Fields:    
    62. Yan T, Wang L, Gao J, Siedlak SL, Huntley ML, Termsarasab P, Perry G, Chen SG, Wang X. Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease. J Alzheimers Dis. 2018; 63(1):157-165. PMID: 29562525.
      Citations:    Fields:    Translation:HumansCells
    63. Perry G, Avila J, Moreira PI, Sorensen AA, Tabaton M. Preface. J Alzheimers Dis. 2018; 64(s1):S1. PMID: 29782320.
      Citations:    Fields:    Translation:Humans
    64. Smith MA, Bowen RL, Nguyen RQ, Perry G, Atwood CS, Rimm AA. Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data. J Alzheimers Dis. 2018; 63(4):1269-1277. PMID: 29782310.
      Citations:    Fields:    Translation:Humans
    65. Perry G, Avila J, Tabaton M, Zhu X. Birth of JAD: 20 Years Later. J Alzheimers Dis. 2018; 62(3):901. PMID: 29562547.
      Citations:    Fields:    
    66. Perry G. Preface. Mini Rev Med Chem. 2018; 18(1):2. PMID: 29283061.
      Citations:    Fields:    
    67. Reale M, D'Angelo C, Costantini E, Di Nicola M, Yarla NS, Kamal MA, Salvador N, Perry G. Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-ß Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology. J Alzheimers Dis. 2018; 62(1):467-476. PMID: 29439355.
      Citations: 1     Fields:    Translation:HumansAnimals
    68. Manyevitch R, Protas M, Scarpiello S, Deliso M, Bass B, Nanajian A, Chang M, Thompson SM, Khoury N, Gonnella R, Trotz M, Moore DB, Harms E, Perry G, Clunes L, Ortiz A, Friedrich JO, Murray IVJ. Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers. Curr Alzheimer Res. 2018; 15(2):164-181. PMID: 28933272.
      Citations: 2     Fields:    Translation:HumansCells
    69. Frank L, Wesson Ashford J, Bayley PJ, Borson S, Buschke H, Cohen D, Cummings JL, Davies P, Dean M, Finkel SI, Hyer L, Perry G, Powers RE, Schmitt F. Genetic Risk of Alzheimer's Disease: Three Wishes Now That the Genie is Out of the Bottle. J Alzheimers Dis. 2018; 66(2):421-423. PMID: 30282369.
      Citations:    Fields:    Translation:Humans
    70. Vasquez V, Mitra J, Perry G, Rao KS, Hegde ML. An Inducible Alpha-Synuclein Expressing Neuronal Cell Line Model for Parkinson's Disease1. J Alzheimers Dis. 2018; 66(2):453-460. PMID: 30320583.
      Citations: 1     Fields:    Translation:HumansCells
    71. Iverson GL, Keene CD, Perry G, Castellani RJ. The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features. J Alzheimers Dis. 2018; 61(1):17-28. PMID: 29103039.
      Citations: 5     Fields:    Translation:Humans
    72. Rodriguez RA, Chen LY, Plascencia-Villa G, Perry G. Thermodynamics of Amyloid-ß Fibril Elongation: Atomistic Details of the Transition State. ACS Chem Neurosci. 2018 04 18; 9(4):783-789. PMID: 29239603.
      Citations:    Fields:    Translation:HumansCells
    73. Zabel M, Nackenoff A, Kirsch WM, Harrison FE, Perry G, Schrag M. Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens. Free Radic Biol Med. 2018 02 01; 115:351-360. PMID: 29253591.
      Citations: 2     Fields:    Translation:Humans
    74. Cornejo A, Aguilar Sandoval F, Caballero L, Machuca L, Muñoz P, Caballero J, Perry G, Ardiles A, Areche C, Melo F. Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to ß sheet in tau protein linked to Alzheimer's disease. J Enzyme Inhib Med Chem. 2017 Dec; 32(1):945-953. PMID: 28701064.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    75. Henderson LE, Abdelmegeed MA, Yoo SH, Rhee SG, Zhu X, Smith MA, Nguyen RQ, Perry G, Song BJ. Enhanced Phosphorylation of Bax and Its Translocation into Mitochondria in the Brains of Individuals Affiliated with Alzheimer's Disease. Open Neurol J. 2017; 11:48-58. PMID: 29290835.
      Citations:    
    76. Wang W, Yin J, Ma X, Zhao F, Siedlak SL, Wang Z, Torres S, Fujioka H, Xu Y, Perry G, Zhu X. Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model. Hum Mol Genet. 2017 11 01; 26(21):4118-4131. PMID: 28973308.
      Citations: 12     Fields:    Translation:AnimalsCells
    77. Martín-Maestro P, Gargini R, García E, Perry G, Avila J, García-Escudero V. Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. Oxid Med Cell Longev. 2017; 2017:9302761. PMID: 29201274.
      Citations: 7     Fields:    Translation:HumansCells
    78. Wambo TO, Chen LY, Phelix C, Perry G. Affinity and path of binding xylopyranose unto E. coli xylose permease. Biochem Biophys Res Commun. 2017 12 09; 494(1-2):202-206. PMID: 29032199.
      Citations: 1     Fields:    Translation:Cells
    79. Barh D, García-Solano ME, Tiwari S, Bhattacharya A, Jain N, Torres-Moreno D, Ferri B, Silva A, Azevedo V, Ghosh P, Blum K, Conesa-Zamora P, Perry G. BARHL1 Is Downregulated in Alzheimer's Disease and May Regulate Cognitive Functions through ESR1 and Multiple Pathways. Genes (Basel). 2017 Sep 28; 8(10). PMID: 28956815.
      Citations: 1     Fields:    
    80. Perry GH, Codding BF. Monkeys overharvest shellfish. Elife. 2017 09 13; 6. PMID: 28902612.
      Citations:    Fields:    Translation:HumansAnimals
    81. Marciniak S, Perry GH. Harnessing ancient genomes to study the history of human adaptation. Nat Rev Genet. 2017 11; 18(11):659-674. PMID: 28890534.
      Citations: 11     Fields:    Translation:HumansAnimals
    82. Peluso I, Yarla NS, Ambra R, Pastore G, Perry G. MAPK signalling pathway in cancers: Olive products as cancer preventive and therapeutic agents. Semin Cancer Biol. 2019 06; 56:185-195. PMID: 28912082.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    83. Kistler L, Johnson SM, Irwin MT, Louis EE, Ratan A, Perry GH. A massively parallel strategy for STR marker development, capture, and genotyping. Nucleic Acids Res. 2017 Sep 06; 45(15):e142. PMID: 28666376.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    84. Trizzino M, Park Y, Holsbach-Beltrame M, Aracena K, Mika K, Caliskan M, Perry GH, Lynch VJ, Brown CD. Transposable elements are the primary source of novelty in primate gene regulation. Genome Res. 2017 10; 27(10):1623-1633. PMID: 28855262.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    85. Nunomura A, Lee HG, Zhu X, Perry G. Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders. Biochem Soc Trans. 2017 Oct 15; 45(5):1053-1066. PMID: 28778984.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    86. Bankoff RJ, Jerjos M, Hohman B, Lauterbur ME, Kistler L, Perry GH. Testing Convergent Evolution in Auditory Processing Genes between Echolocating Mammals and the Aye-Aye, a Percussive-Foraging Primate. Genome Biol Evol. 2017 07 01; 9(7):1978-1989. PMID: 28810710.
      Citations:    Fields:    Translation:Animals
    87. Hajipour MJ, Santoso MR, Rezaee F, Aghaverdi H, Mahmoudi M, Perry G. Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology. Trends Biotechnol. 2017 10; 35(10):937-953. PMID: 28666544.
      Citations: 9     Fields:    Translation:HumansAnimals
    88. Sullivan AP, de Manuel M, Marques-Bonet T, Perry GH. An evolutionary medicine perspective on Neandertal extinction. J Hum Evol. 2017 07; 108:62-71. PMID: 28622932.
      Citations: 3     Fields:    Translation:HumansAnimals
    89. Patin E, Lopez M, Grollemund R, Verdu P, Harmant C, Quach H, Laval G, Perry GH, Barreiro LB, Froment A, Heyer E, Massougbodji A, Fortes-Lima C, Migot-Nabias F, Bellis G, Dugoujon JM, Pereira JB, Fernandes V, Pereira L, Van der Veen L, Mouguiama-Daouda P, Bustamante CD, Hombert JM, Quintana-Murci L. Dispersals and genetic adaptation of Bantu-speaking populations in Africa and North America. Science. 2017 05 05; 356(6337):543-546. PMID: 28473590.
      Citations: 19     Fields:    Translation:Humans
    90. Rodriguez RA, Chen LY, Plascencia-Villa G, Perry G. Elongation affinity, activation barrier, and stability of Aß42 oligomers/fibrils in physiological saline. Biochem Biophys Res Commun. 2017 05 27; 487(2):444-449. PMID: 28427941.
      Citations: 4     Fields:    Translation:Cells
    91. Moritz GL, Ong PS, Perry GH, Dominy NJ. Functional preservation and variation in the cone opsin genes of nocturnal tarsiers. Philos Trans R Soc Lond B Biol Sci. 2017 Apr 05; 372(1717). PMID: 28193820.
      Citations: 3     Fields:    Translation:Animals
    92. Vukelic A, Cohen JA, Sullivan AP, Perry GH. Extending Genome-Wide Association Study Results to Test Classic Anthropological Hypotheses: Human Third Molar Agenesis and the "Probable Mutation Effect". Hum Biol. 2017 04; 89(2):157-169. PMID: 29299963.
      Citations:    Fields:    Translation:HumansAnimals
    93. Chase CCL, Fulton RW, O'Toole D, Gillette B, Daly RF, Perry G, Clement T. Bovine herpesvirus 1 modified live virus vaccines for cattle reproduction: Balancing protection with undesired effects. Vet Microbiol. 2017 Jul; 206:69-77. PMID: 28377131.
      Citations: 6     Fields:    Translation:AnimalsCellsPHPublic Health
    94. Lei R, Frasier CL, Hawkins MT, Engberg SE, Bailey CA, Johnson SE, McLain AT, Groves CP, Perry GH, Nash SD, Mittermeier RA, Louis EE. Phylogenomic Reconstruction of Sportive Lemurs (genus Lepilemur) Recovered from Mitogenomes with Inferences for Madagascar Biogeography. J Hered. 2017 03 01; 108(2):107-119. PMID: 28173059.
      Citations: 1     Fields:    Translation:Animals
    95. Khalsa DS, Perry G. The Four Pillars of Alzheimer's Prevention. Cerebrum. 2017 Mar-Apr; 2017. PMID: 28698774.
      Citations:    
    96. Sullivan AP, Bird DW, Perry GH. Human behaviour as a long-term ecological driver of non-human evolution. Nat Ecol Evol. 2017 Feb 21; 1(3):65. PMID: 28812734.
      Citations: 8     Fields:    
    97. Doens D, Valiente PA, Mfuh AM, X T Vo A, Tristan A, Carreño L, Quijada M, Nguyen VT, Perry G, Larionov OV, Lleonart R, Fernández PL. Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease. ACS Chem Neurosci. 2017 06 21; 8(6):1232-1241. PMID: 28150942.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    98. Remington R, Shea TB, Perry G. Nutritional supplements and dementia. Clin Nutr. 2017 04; 36(2):613-614. PMID: 28153502.
      Citations:    Fields:    Translation:Humans
    99. Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. J Alzheimers Dis. 2017; 55(2):749-762. PMID: 27802219.
      Citations: 3     Fields:    Translation:HumansCells
    100. Nunomura A, Zhu X, Perry G. Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration. J Alzheimers Dis. 2017; 55(1):73-75. PMID: 27802241.
      Citations: 2     Fields:    Translation:HumansAnimals
    101. Mondragón-Rodríguez S, Perry G, Pena-Ortega F, Williams S. Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease. Curr Alzheimer Res. 2017; 14(1):40-46. PMID: 27539594.
      Citations: 1     Fields:    Translation:AnimalsCells
    102. Putta S, Yarla NS, Peluso I, Tiwari DK, Reddy GV, Giri PV, Kumar N, Malla R, Rachel V, Bramhachari PV, Reddy D RS, Bade R, Mannarapu M, Barreto GE, Lu DY, Tarasov VV, Chubarev VN, Ribeiro FF, Scotti L, Scotti MT, Kamal MA, Ashraf GM, Aliev G, Perry G, Sarker SD, Rao CV, Bishayee A. Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases. Curr Pharm Des. 2017; 23(41):6321-6346. PMID: 28741457.
      Citations: 1     Fields:    Translation:HumansAnimals
    103. Siedlak SL, Jiang Y, Huntley ML, Wang L, Gao J, Xie F, Liu J, Su B, Perry G, Wang X. TMEM230 Accumulation in Granulovacuolar Degeneration Bodies and Dystrophic Neurites of Alzheimer's Disease. J Alzheimers Dis. 2017; 58(4):1027-1033. PMID: 28527219.
      Citations: 1     Fields:    Translation:HumansCells
    104. Castellani RJ, Perry G. Dementia Pugilistica Revisited. J Alzheimers Dis. 2017; 60(4):1209-1221. PMID: 29036831.
      Citations:    Fields:    Translation:HumansAnimals
    105. Forero DA, Prada CF, Perry G. Functional and Genomic Features of Human Genes Mutated in Neuropsychiatric Disorders. Open Neurol J. 2016; 10:143-148. PMID: 27990183.
      Citations:    
    106. Castellani RJ, Mojica G, Perry G. The Role of the Iron Stain in Assessing Intracranial Hemorrhage. Open Neurol J. 2016; 10:136-142. PMID: 27857815.
      Citations:    
    107. Perry G. Promise from the Sea. Mar Drugs. 2016 Oct 09; 14(10). PMID: 27735831.
      Citations:    Fields:    Translation:HumansAnimals
    108. Kelley AR, Perry G, Bethea C, Castellani RJ, Bach SB. Molecular Mapping Alzheimer's Disease: MALDI Imaging of Formalin-fixed, Paraffin-embedded Human Hippocampal Tissue. Open Neurol J. 2016; 10:88-98. PMID: 27843502.
      Citations:    
    109. Aryan N, Betts-Obregon BS, Perry G, Tsin AT. Oxidative Stress Induces Senescence in Cultured RPE Cells. Open Neurol J. 2016; 10:83-7. PMID: 27651846.
      Citations:    
    110. Hubbard TD, Murray IA, Bisson WH, Sullivan AP, Sebastian A, Perry GH, Jablonski NG, Perdew GH. Divergent Ah Receptor Ligand Selectivity during Hominin Evolution. Mol Biol Evol. 2016 10; 33(10):2648-58. PMID: 27486223.
      Citations: 4     Fields:    Translation:HumansAnimals
    111. Correia SC, Perry G, Moreira PI. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks. Biochim Biophys Acta. 2016 10; 1862(10):1909-17. PMID: 27460705.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    112. Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, Perry G, Odetti P, Arancio O, Tamagno E, Tabaton M. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. 2016 10; 15(5):914-23. PMID: 27406053.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    113. Bankoff RJ, Perry GH. Hunter-gatherer genomics: evolutionary insights and ethical considerations. Curr Opin Genet Dev. 2016 Dec; 41:1-7. PMID: 27400119.
      Citations:    Fields:    Translation:Humans
    114. Herrera L, Stephens DE, D'Avila A, George KG, Arman H, Zhang Y, Perry G, Lleonart R, Larionov OV, Fernández PL. Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles. Org Biomol Chem. 2016 Aug 07; 14(29):7053-60. PMID: 27376396.
      Citations: 2     Fields:    Translation:AnimalsCells
    115. Pistollato F, Ohayon EL, Lam A, Langley GR, Novak TJ, Pamies D, Perry G, Trushina E, Williams RS, Roher AE, Hartung T, Harnad S, Barnard N, Morris MC, Lai MC, Merkley R, Chandrasekera PC. Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities. Oncotarget. 2016 Jun 28; 7(26):38999-39016. PMID: 27229915.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    116. Hofer T, Perry G. Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis? J Trace Elem Med Biol. 2016 Dec; 38:1-9. PMID: 27329321.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    117. Plascencia-Villa G, Ponce A, Collingwood JF, Arellano-Jiménez MJ, Zhu X, Rogers JT, Betancourt I, José-Yacamán M, Perry G. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Sci Rep. 2016 04 28; 6:24873. PMID: 27121137.
      Citations: 17     Fields:    Translation:Humans
    118. Forero DA, González-Giraldo Y, López-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Meta-analysis of Telomere Length in Alzheimer's Disease. J Gerontol A Biol Sci Med Sci. 2016 08; 71(8):1069-73. PMID: 27091133.
      Citations: 23     Fields:    Translation:HumansCells
    119. Federman S, Dornburg A, Daly DC, Downie A, Perry GH, Yoder AD, Sargis EJ, Richard AF, Donoghue MJ, Baden AL. Implications of lemuriform extinctions for the Malagasy flora. Proc Natl Acad Sci U S A. 2016 May 03; 113(18):5041-6. PMID: 27071108.
      Citations: 8     Fields:    Translation:Animals
    120. Ontiveros-Torres MÁ, Labra-Barrios ML, Díaz-Cintra S, Aguilar-Vázquez AR, Moreno-Campuzano S, Flores-Rodríguez P, Luna-Herrera C, Mena R, Perry G, Florán-Garduño B, Luna-Muñoz J, Luna-Arias JP. Fibrillar Amyloid-ß Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3×Tg-AD Transgenic Mouse. J Alzheimers Dis. 2016 03 22; 52(1):243-69. PMID: 27031470.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    121. Wang C, Zhang F, Jiang S, Siedlak SL, Shen L, Perry G, Wang X, Tang B, Zhu X. Estrogen receptor-a is localized to neurofibrillary tangles in Alzheimer's disease. Sci Rep. 2016 Feb 03; 6:20352. PMID: 26837465.
      Citations: 5     Fields:    Translation:HumansCells
    122. Yu L, Rodriguez RA, Chen LL, Chen LY, Perry G, McHardy SF, Yeh CK. 1,3-propanediol binds deep inside the channel to inhibit water permeation through aquaporins. Protein Sci. 2016 Feb; 25(2):433-41. PMID: 26481430.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    123. Calderón-Garcidueñas L, Reynoso-Robles R, Vargas-Martínez J, Gómez-Maqueo-Chew A, Pérez-Guillé B, Mukherjee PS, Torres-Jardón R, Perry G, Gónzalez-Maciel A. Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease. Environ Res. 2016 Apr; 146:404-17. PMID: 26829765.
      Citations: 19     Fields:    Translation:HumansAnimalsPHPublic Health
    124. Forero DA, González-Giraldo Y, López-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Telomere length in Parkinson's disease: A meta-analysis. Exp Gerontol. 2016 Mar; 75:53-5. PMID: 26772888.
      Citations: 10     Fields:    Translation:HumansCells
    125. Kelley AR, Perry G, Castellani RJ, Bach SB. Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer's Brains. ACS Chem Neurosci. 2016 Mar 16; 7(3):261-8. PMID: 26720297.
      Citations: 3     Fields:    Translation:Humans
    126. Forero DA, Wonkam A, Wang W, Laissue P, López-Correa C, Fernández-López JC, Mugasimangalam R, Perry G. Current needs for human and medical genomics research infrastructure in low and middle income countries. J Med Genet. 2016 07; 53(7):438-40. PMID: 26740506.
      Citations: 2     Fields:    Translation:Humans
    127. Melin AD, Wells K, Moritz GL, Kistler L, Orkin JD, Timm RM, Bernard H, Lakim MB, Perry GH, Kawamura S, Dominy NJ. Euarchontan Opsin Variation Brings New Focus to Primate Origins. Mol Biol Evol. 2016 Apr; 33(4):1029-41. PMID: 26739880.
      Citations: 5     Fields:    Translation:HumansAnimals
    128. Itzhaki RF, Lathe R, Balin BJ, Ball MJ, Bearer EL, Braak H, Bullido MJ, Carter C, Clerici M, Cosby SL, Del Tredici K, Field H, Fulop T, Grassi C, Griffin WS, Haas J, Hudson AP, Kamer AR, Kell DB, Licastro F, Letenneur L, Lövheim H, Mancuso R, Miklossy J, Otth C, Palamara AT, Perry G, Preston C, Pretorius E, Strandberg T, Tabet N, Taylor-Robinson SD, Whittum-Hudson JA. Microbes and Alzheimer's Disease. J Alzheimers Dis. 2016; 51(4):979-84. PMID: 26967229.
      Citations: 66     Fields:    Translation:HumansAnimals
    129. Martín-Maestro P, Gargini R, Perry G, Avila J, García-Escudero V. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. Hum Mol Genet. 2016 Feb 15; 25(4):792-806. PMID: 26721933.
      Citations: 15     Fields:    Translation:HumansCells
    130. Singh SK, Srivastav S, Yadav AK, Srikrishna S, Perry G. Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aß by Using Several Synthetic and Herbal Compounds. Oxid Med Cell Longev. 2016; 2016:7361613. PMID: 27034741.
      Citations: 13     Fields:    Translation:HumansAnimals
    131. Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016 09; 21(9):1263-71. PMID: 26619807.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    132. Kistler L, Newsom LA, Ryan TM, Clarke AC, Smith BD, Perry GH. Gourds and squashes (Cucurbita spp.) adapted to megafaunal extinction and ecological anachronism through domestication. Proc Natl Acad Sci U S A. 2015 Dec 08; 112(49):15107-12. PMID: 26630007.
      Citations: 15     Fields:    Translation:AnimalsCells
    133. Jiang Z, Wang W, Perry G, Zhu X, Wang X. Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis. Transl Neurodegener. 2015; 4:14. PMID: 26225210.
      Citations:    
    134. Lynch VJ, Bedoya-Reina OC, Ratan A, Sulak M, Drautz-Moses DI, Perry GH, Miller W, Schuster SC. Elephantid Genomes Reveal the Molecular Bases of Woolly Mammoth Adaptations to the Arctic. Cell Rep. 2015 Jul 14; 12(2):217-28. PMID: 26146078.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    135. Calderón-Garcidueñas L, Franco-Lira M, D'Angiulli A, Rodríguez-Díaz J, Blaurock-Busch E, Busch Y, Chao CK, Thompson C, Mukherjee PS, Torres-Jardón R, Perry G. Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease. Environ Res. 2015 Jul; 140:579-92. PMID: 26037109.
      Citations: 12     Fields:    Translation:Humans
    136. Castellani RJ, Perry G, Iverson GL. Chronic effects of mild neurotrauma: putting the cart before the horse? J Neuropathol Exp Neurol. 2015 Jun; 74(6):493-9. PMID: 25933385.
      Citations: 11     Fields:    Translation:Humans
    137. Zhang F, Wang W, Siedlak SL, Liu Y, Liu J, Jiang K, Perry G, Zhu X, Wang X. Miro1 deficiency in amyotrophic lateral sclerosis. Front Aging Neurosci. 2015; 7:100. PMID: 26074815.
      Citations:    
    138. Zhang F, Su B, Wang C, Siedlak SL, Mondragon-Rodriguez S, Lee HG, Wang X, Perry G, Zhu X. Posttranslational modifications of a-tubulin in alzheimer disease. Transl Neurodegener. 2015; 4:9. PMID: 26029362.
      Citations:    
    139. Gerenu G, Liu K, Chojnacki JE, Saathoff JM, Martínez-Martín P, Perry G, Zhu X, Lee HG, Zhang S. Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model. ACS Chem Neurosci. 2015 Aug 19; 6(8):1393-1399. PMID: 25893520.
      Citations: 5     Fields:    Translation:AnimalsCells
    140. Avila J, Perry G, Strange BA, Hernandez F. Alternative neural circuitry that might be impaired in the development of Alzheimer disease. Front Neurosci. 2015; 9:145. PMID: 25954151.
      Citations:    
    141. Rodriguez AR, Plascencia-Villa G, Witt CM, Yu JJ, José-Yacamán M, Chambers JP, Perry G, Guentzel MN, Arulanandam BP. Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells. Cell Immunol. 2015 Jun; 295(2):83-91. PMID: 25863744.
      Citations: 2     Fields:    Translation:AnimalsCells
    142. Pelcovits A, Marriotti R, Heath J, Perry G, Castellani RJ. Simultaneous onset of Alzheimer's disease in a husband and wife in their mid-fifties: what do we really know about environmental factors? Open Neurol J. 2015; 9:1-3. PMID: 25932054.
      Citations:    
    143. Carvalho C, Correia SC, Perry G, Castellani RJ, Moreira PI. Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview. J Neural Transm (Vienna). 2016 Feb; 123(2):107-11. PMID: 25608860.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    144. Perry GH, Orlando L. Ancient DNA and human evolution. J Hum Evol. 2015 Feb; 79:1-3. PMID: 25619123.
      Citations:    Fields:    Translation:HumansAnimals
    145. Perry GH, Kistler L, Kelaita MA, Sams AJ. Insights into hominin phenotypic and dietary evolution from ancient DNA sequence data. J Hum Evol. 2015 Feb; 79:55-63. PMID: 25563409.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    146. Perry G. Two hundred treasured issues! J Alzheimers Dis. 2015; 44(3):725. PMID: 25663057.
      Citations:    Fields:    Translation:Humans
    147. Luna-Muñoz J, Perry G, Guevara J. Raúl Mena: 1953-2014. J Alzheimers Dis. 2015; 45(2):325-7. PMID: 25757649.
      Citations:    Fields:    Translation:Humans
    148. Petersen RB, Lissemore FM, Appleby B, Aggarwal N, Boyatzis R, Casadesus G, Cummings J, Jack A, Perry G, Safar J, Sajatovic M, Surewicz WK, Wang Y, Whitehouse P, Lerner A. From Neurodegeneration to Brain Health: An Integrated Approach. J Alzheimers Dis. 2015; 46(1):271-83. PMID: 25720413.
      Citations:    Fields:    Translation:HumansAnimals
    149. Spremo-Potparevic B, Bajic V, Perry G, Zivkovic L. Alterations of the X Chromosome in Lymphocytes of Alzheimer's Disease Patients. Curr Alzheimer Res. 2015; 12(10):990-6. PMID: 26502819.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    150. Bowen RL, Perry G, Xiong C, Smith MA, Atwood CS. A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks. J Alzheimers Dis. 2015; 44(2):549-60. PMID: 25310993.
      Citations: 11     Fields:    Translation:Humans
    151. Forero DA, Vélez-van-Meerbeke A, Deshpande SN, Nicolini H, Perry G. Neuropsychiatric genetics in developing countries: Current challenges. World J Psychiatry. 2014 Dec 22; 4(4):69-71. PMID: 25540721.
      Citations:    
    152. Kistler L, Ratan A, Godfrey LR, Crowley BE, Hughes CE, Lei R, Cui Y, Wood ML, Muldoon KM, Andriamialison H, McGraw JJ, Tomsho LP, Schuster SC, Miller W, Louis EE, Yoder AD, Malhi RS, Perry GH. Comparative and population mitogenomic analyses of Madagascar's extinct, giant 'subfossil' lemurs. J Hum Evol. 2015 Feb; 79:45-54. PMID: 25523037.
      Citations: 14     Fields:    Translation:Animals
    153. Fornicola W, Pelcovits A, Li BX, Heath J, Perry G, Castellani RJ. Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-ß and Phosphorylated Tau. Open Neurol J. 2014; 8:22-6. PMID: 25628768.
      Citations:    
    154. Kim HL, Ratan A, Perry GH, Montenegro A, Miller W, Schuster SC. Khoisan hunter-gatherers have been the largest population throughout most of modern-human demographic history. Nat Commun. 2014 Dec 04; 5:5692. PMID: 25471224.
      Citations: 11     Fields:    Translation:Humans
    155. Habibi L, Perry G, Mahmoudi M. Global warming and neurodegenerative disorders: speculations on their linkage. Bioimpacts. 2014; 4(4):167-70. PMID: 25671171.
      Citations:    
    156. Hodgson JA, Pickrell JK, Pearson LN, Quillen EE, Prista A, Rocha J, Soodyall H, Shriver MD, Perry GH. Natural selection for the Duffy-null allele in the recently admixed people of Madagascar. Proc Biol Sci. 2014 Aug 22; 281(1789):20140930. PMID: 24990677.
      Citations: 11     Fields:    Translation:Humans
    157. Perry GH, Foll M, Grenier JC, Patin E, Nédélec Y, Pacis A, Barakatt M, Gravel S, Zhou X, Nsobya SL, Excoffier L, Quintana-Murci L, Dominy NJ, Barreiro LB. Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers. Proc Natl Acad Sci U S A. 2014 09 02; 111(35):E3596-603. PMID: 25136101.
      Citations: 22     Fields:    Translation:Humans
    158. Blekhman R, Perry GH, Shahbaz S, Fiehn O, Clark AG, Gilad Y. Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. Sci Rep. 2014 Jul 28; 4:5809. PMID: 25069065.
      Citations: 5     Fields:    Translation:HumansAnimals
    159. Xia J, Rocke DM, Perry G, Ray M. Differential network analyses of Alzheimer's disease identify early events in Alzheimer's disease pathology. Int J Alzheimers Dis. 2014; 2014:721453. PMID: 25147748.
      Citations:    
    160. Rodrigues R, Petersen RB, Perry G. Parallels between major depressive disorder and Alzheimer's disease: role of oxidative stress and genetic vulnerability. Cell Mol Neurobiol. 2014 Oct; 34(7):925-49. PMID: 24927694.
      Citations: 13     Fields:    Translation:Humans
    161. Blair JA, Siedlak SL, Wolfram JA, Nunomura A, Castellani RJ, Ferreira ST, Klein WL, Wang Y, Casadesus G, Smith MA, Perry G, Zhu X, Lee HG. Accumulation of intraneuronal amyloid-ß is common in normal brain. Curr Alzheimer Res. 2014 May; 11(4):317-24. PMID: 24597504.
      Citations: 6     Fields:    Translation:Humans
    162. Bonda DJ, Wang X, Lee HG, Smith MA, Perry G, Zhu X. Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass. Neurosci Bull. 2014 Apr; 30(2):243-52. PMID: 24733654.
      Citations: 24     Fields:    Translation:HumansCells
    163. Mubiru JN, Yang AS, Olsen C, Nayak S, Livi CB, Dick EJ, Owston M, Garcia-Forey M, Shade RE, Rogers J. Analysis of prostate-specific antigen transcripts in chimpanzees, cynomolgus monkeys, baboons, and African green monkeys. PLoS One. 2014; 9(4):e94522. PMID: 24732672.
      Citations: 2     Fields:    Translation:AnimalsCells
    164. Teka W, Marinov TM, Santamaria F. Neuronal spike timing adaptation described with a fractional leaky integrate-and-fire model. PLoS Comput Biol. 2014 Mar; 10(3):e1003526. PMID: 24675903.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    165. Mondragón-Rodríguez S, Perry G, Luna-Muñoz J, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome. Neuropathol Appl Neurobiol. 2014 Feb; 40(2):121-35. PMID: 24033439.
      Citations: 43     Fields:    Translation:HumansCells
    166. Johnston JM, Hu WT, Fardo DW, Greco SJ, Perry G, Montine TJ, Trojanowski JQ, Shaw LM, Ashford JW, Tezapsidis N. Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential. Curr Alzheimer Res. 2014 Feb; 11(2):165-74. PMID: 24359504.
      Citations: 16     Fields:    Translation:Humans
    167. Perry G, Castellani R. Plaques and tangles: birthmarks of the aging soul. Preface. Biochem Pharmacol. 2014 Apr 15; 88(4):423-5. PMID: 24486570.
      Citations:    Fields:    Translation:HumansCells
    168. Guajardo LF, Wicha NY. Morphosyntax can modulate the N400 component: event related potentials to gender-marked post-nominal adjectives. Neuroimage. 2014 May 01; 91:262-72. PMID: 24462934.
      Citations: 3     Fields:    Translation:Humans
    169. Castellani RJ, Perry G. The complexities of the pathology-pathogenesis relationship in Alzheimer disease. Biochem Pharmacol. 2014 Apr 15; 88(4):671-6. PMID: 24447936.
      Citations: 22     Fields:    Translation:Humans
    170. Fok WC, Chen Y, Bokov A, Zhang Y, Salmon AB, Diaz V, Javors M, Wood WH, Zhang Y, Becker KG, Pérez VI, Richardson A. Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome. PLoS One. 2014; 9(1):e83988. PMID: 24409289.
      Citations: 49     Fields:    Translation:AnimalsCells
    171. Rosen AC, Ashford JW, Perry G. Ethics review as a catalyst for progress. J Alzheimers Dis. 2014; 40(2):233-5. PMID: 24583402.
      Citations:    Fields:    Translation:HumansAnimals
    172. Fawver JN, Ghiwot Y, Koola C, Carrera W, Rodriguez-Rivera J, Hernandez C, Dineley KT, Kong Y, Li J, Jhamandas J, Perry G, Murray IV. Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease. Curr Alzheimer Res. 2014; 11(10):928-40. PMID: 25387341.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    173. Brinkley WR, Perry G. Lester (Skip) Binder (1949-2013): in the beginning was tau. J Alzheimers Dis. 2014; 40 Suppl 1:S5. PMID: 24867914.
      Citations:    Fields:    Translation:HumansAnimals
    174. Patin E, Siddle KJ, Laval G, Quach H, Harmant C, Becker N, Froment A, Régnault B, Lemée L, Gravel S, Hombert JM, Van der Veen L, Dominy NJ, Perry GH, Barreiro LB, Verdu P, Heyer E, Quintana-Murci L. The impact of agricultural emergence on the genetic history of African rainforest hunter-gatherers and agriculturalists. Nat Commun. 2014; 5:3163. PMID: 24495941.
      Citations: 21     Fields:    
    175. Hoffmann C, Zimmermann A, Hinney A, Volckmar AL, Jarrett HW, Fromme T, Klingenspor M. A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes. PLoS One. 2013; 8(12):e83426. PMID: 24391766.
      Citations: 9     Fields:    Translation:AnimalsCells
    176. Bharadwaj PR, Bates KA, Porter T, Teimouri E, Perry G, Steele JW, Gandy S, Groth D, Martins RN, Verdile G. Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases. Transl Psychiatry. 2013 Dec 03; 3:e332. PMID: 24301650.
      Citations: 14     Fields:    Translation:HumansAnimals
    177. Jarero-Basulto JJ, Luna-Muñoz J, Mena R, Kristofikova Z, Ripova D, Perry G, Binder LI, Garcia-Sierra F. Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease. J Neuropathol Exp Neurol. 2013 Dec; 72(12):1145-61. PMID: 24226268.
      Citations: 8     Fields:    Translation:HumansCells
    178. Sosa RA, Murphey C, Ji N, Cardona AE, Forsthuber TG. The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2013 Dec 15; 191(12):5848-57. PMID: 24227784.
      Citations: 18     Fields:    Translation:AnimalsCellsPHPublic Health
    179. Fujioka H, Phelix CF, Friedland RP, Zhu X, Perry EA, Castellani RJ, Perry G. Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease. J Health Care Poor Underserved. 2013 Nov; 24(4 Suppl):70-8. PMID: 24241262.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    180. Wang X, Wang W, Li L, Perry G, Lee HG, Zhu X. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochim Biophys Acta. 2014 Aug; 1842(8):1240-7. PMID: 24189435.
      Citations: 147     Fields:    Translation:HumansAnimalsCells
    181. Paley EL, Perry G, Sokolova O. Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency. Curr Alzheimer Res. 2013 Nov; 10(9):987-1004. PMID: 24117115.
      Citations: 2     Fields:    Translation:AnimalsCells
    182. Williams WM, Torres S, Siedlak SL, Castellani RJ, Perry G, Smith MA, Zhu X. Antimicrobial peptide ß-defensin-1 expression is upregulated in Alzheimer's brain. J Neuroinflammation. 2013 Oct 18; 10:127. PMID: 24139179.
      Citations: 12     Fields:    Translation:HumansCells
    183. Correia SC, Perry G, Castellani R, Moreira PI. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease? J Neurochem. 2013 Oct; 127(1):4-6. PMID: 24074055.
      Citations: 1     Fields:    Translation:HumansAnimals
    184. Li W, Murthy AK, Lanka GK, Chetty SL, Yu JJ, Chambers JP, Zhong G, Forsthuber TG, Guentzel MN, Arulanandam BP. A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice. Vaccine. 2013 Nov 19; 31(48):5722-8. PMID: 24096029.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    185. Bonda DJ, Stone JG, Torres SL, Siedlak SL, Perry G, Kryscio R, Jicha G, Casadesus G, Smith MA, Zhu X, Lee HG. Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance. J Neurochem. 2014 Jan; 128(1):162-72. PMID: 23895348.
      Citations: 34     Fields:    Translation:HumansCells
    186. Schrag M, Mueller C, Zabel M, Crofton A, Kirsch WM, Ghribi O, Squitti R, Perry G. Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis. Neurobiol Dis. 2013 Nov; 59:100-10. PMID: 23867235.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    187. Mondragón-Rodríguez S, Perry G, Zhu X, Moreira PI, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease. Oxid Med Cell Longev. 2013; 2013:940603. PMID: 23936615.
      Citations: 24     Fields:    Translation:HumansCells
    188. Nagore LI, Nadeau RJ, Guo Q, Jadhav YL, Jarrett HW, Haskins WE. Purification and characterization of transcription factors. Mass Spectrom Rev. 2013 Sep-Oct; 32(5):386-98. PMID: 23832591.
      Citations:    Fields:    Translation:HumansAnimalsCells
    189. García-Escudero V, Martín-Maestro P, Perry G, Avila J. Deconstructing mitochondrial dysfunction in Alzheimer disease. Oxid Med Cell Longev. 2013; 2013:162152. PMID: 23840916.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    190. Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free Radic Res. 2013 Jul; 47(6-7):507-10. PMID: 23566300.
      Citations: 5     Fields:    Translation:Animals
    191. Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Curr Alzheimer Res. 2013 May 01; 10(4):406-19. PMID: 23061885.
      Citations: 17     Fields:    Translation:AnimalsCells
    192. Perry G. Reply: comments on "The effects of vaccination on serum hormone concentrations and conception rates in synchronized naive beef heifers". Theriogenology. 2013 Jul 01; 80(1):71. PMID: 23628363.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    193. Haldar S, Beveridge 'J, Wong J, Singh A, Galimberti D, Borroni B, Zhu X, Blevins J, Greenlee J, Perry G, Mukhopadhyay CK, Schmotzer C, Singh N. A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD. Antioxid Redox Signal. 2013 Nov 10; 19(14):1662-75. PMID: 23379482.
      Citations: 6     Fields:    Translation:Humans
    194. Perry GH, Louis EE, Ratan A, Bedoya-Reina OC, Burhans RC, Lei R, Johnson SE, Schuster SC, Miller W. Aye-aye population genomic analyses highlight an important center of endemism in northern Madagascar. Proc Natl Acad Sci U S A. 2013 Apr 09; 110(15):5823-8. PMID: 23530231.
      Citations: 12     Fields:    Translation:Animals
    195. Durán-González J, Michi ED, Elorza B, Perez-Córdova MG, Pacheco-Otalora LF, Touhami A, Paulson P, Perry G, Murray IV, Colom LV. Amyloid ß peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system. Neurobiol Aging. 2013 Aug; 34(8):2071-6. PMID: 23473707.
      Citations: 6     Fields:    Translation:Animals
    196. Zivkovic L, Spremo-Potparevic B, Siedlak SL, Perry G, Plecaš-Solarovic B, Milicevic Z, Bajic VP. DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division. Neurodegener Dis. 2013; 12(3):156-63. PMID: 23406622.
      Citations: 5     Fields:    Translation:HumansCells
    197. Perry G, Zhu X, Smith MA, Sorensen A, Avila J. Preface. Alzheimer's disease: advances for a new century. J Alzheimers Dis. 2013; 33 Suppl 1:S1. PMID: 23397602.
      Citations: 2     Fields:    Translation:Humans
    198. Colom LV, Perry G, Kuljis RO. Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease. Curr Alzheimer Res. 2013 Jan; 10(1):108-16. PMID: 23368433.
      Citations: 3     Fields:    Translation:Humans
    199. Perry G. The largest unmet market: chronic diseases of aging. Mini Rev Med Chem. 2013 Jan; 13(1):1. PMID: 23447815.
      Citations:    Fields:    Translation:Humans
    200. Zhu X, Perry G, Smith MA, Wang X. Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis. 2013; 33 Suppl 1:S253-62. PMID: 22531428.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    201. Hou L, Lee HG, Han F, Tedesco JM, Perry G, Smith MA, Zagorski MG. Modification of amyloid-ß1-42 fibril structure by methionine-35 oxidation. J Alzheimers Dis. 2013; 37(1):9-18. PMID: 23719512.
      Citations: 7     Fields:    Translation:HumansCells
    202. Coskuner O, Wise-Scira O, Perry G, Kitahara T. The structures of the E22? mutant-type amyloid-ß alloforms and the impact of E22? mutation on the structures of the wild-type amyloid-ß alloforms. ACS Chem Neurosci. 2013 Feb 20; 4(2):310-20. PMID: 23421682.
      Citations: 11     Fields:    Translation:HumansCells
    203. Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxid Redox Signal. 2013 Jun 20; 18(18):2444-57. PMID: 23216311.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    204. Greco SJ, Hamzelou A, Johnston JM, Richardson S, Smith MA, Perry G, Ashford JW, Tezapsidis N. Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest. Curr Alzheimer Res. 2012 Dec; 9(10):1168-73. PMID: 22950840.
      Citations:    Fields:    Translation:Humans
    205. Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Plácido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. IUBMB Life. 2012 Dec; 64(12):951-7. PMID: 23129399.
      Citations: 18     Fields:    Translation:HumansCells
    206. Castellani RJ, Perry G. Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress. Arch Med Res. 2012 Nov; 43(8):694-8. PMID: 23085451.
      Citations: 25     Fields:    Translation:HumansCells
    207. Miklossy J, Donta S, Mueller K, Nolte O, Perry G. Chronic or late lyme neuroborreliosis: present and future. Open Neurol J. 2012; 6:78. PMID: 23091567.
      Citations:    
    208. Villanea FA, Perry GH, Gutiérrez-Espeleta GA, Dominy NJ. ASPM and the evolution of cerebral cortical size in a community of New World monkeys. PLoS One. 2012; 7(9):e44928. PMID: 23028686.
      Citations:    Fields:    Translation:HumansAnimals
    209. Morelli L, Perry G, Tagliavini F. The contribution of the amyloid hypothesis to the understanding of Alzheimer's disease: a critical overview. Int J Alzheimers Dis. 2012; 2012:709613. PMID: 22970405.
      Citations:    
    210. Iskow RC, Gokcumen O, Abyzov A, Malukiewicz J, Zhu Q, Sukumar AT, Pai AA, Mills RE, Habegger L, Cusanovich DA, Rubel MA, Perry GH, Gerstein M, Stone AC, Gilad Y, Lee C. Regulatory element copy number differences shape primate expression profiles. Proc Natl Acad Sci U S A. 2012 Jul 31; 109(31):12656-61. PMID: 22797897.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    211. Piccini A, Borghi R, Guglielmotto M, Tamagno E, Cirmena G, Garuti A, Pollero V, Cammarata S, Fornaro M, Messa M, Colombo L, Salmona M, Perry G, Tabaton M. ß-amyloid 1-42 induces physiological transcriptional regulation of BACE1. J Neurochem. 2012 Sep; 122(5):1023-31. PMID: 22708832.
      Citations: 10     Fields:    Translation:HumansCells
    212. Mondragón-Rodríguez S, Perry G, Zhu X, Moreira PI, Williams S. Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target? Int J Alzheimers Dis. 2012; 2012:276803. PMID: 22779025.
      Citations:    
    213. Wise-Scira O, Xu L, Perry G, Coskuner O. Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-ß(1-40) and zinc(II)-bound amyloid-ß(1-42) with dynamics. J Biol Inorg Chem. 2012 Aug; 17(6):927-38. PMID: 22674434.
      Citations: 11     Fields:    Translation:Cells
    214. Nunomura A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotox Res. 2012 Oct; 22(3):231-48. PMID: 22669748.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    215. Rodrigues R, Smith MA, Wang X, Perry G, Lee HG, Zhu X, Petersen RB. Molecular neuropathogenesis of Alzheimer's disease: an interaction model stressing the central role of oxidative stress. Future Neurol. 2012 May; 7(3):287-305. PMID: 23086377.
      Citations:    
    216. Liu G, Men P, Zhu X, Perry G. Iron chelation and nanoparticle target delivery in the development of new multifunctional disease-modifying drugs for Alzheimer's disease. Ther Deliv. 2012 May; 3(5):571-4. PMID: 22834400.
      Citations: 1     Fields:    Translation:HumansAnimals
    217. Williams WM, Castellani RJ, Weinberg A, Perry G, Smith MA. Do ß-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration? ScientificWorldJournal. 2012; 2012:905785. PMID: 22606066.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    218. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, Bánhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, Béchet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahová M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronjé MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farré JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, Fésüs L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490.
      Citations: 1450     Fields:    Translation:HumansAnimals
    219. Castellani RJ, Moreira PI, Perry G, Zhu X. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors. 2012 Mar-Apr; 38(2):133-8. PMID: 22447715.
      Citations: 16     Fields:    Translation:HumansAnimals
    220. Mondragón-Rodríguez S, Perry G, Zhu X, Boehm J. Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy. Int J Alzheimers Dis. 2012; 2012:630182. PMID: 22482074.
      Citations:    
    221. Nunomura A, Tamaoki T, Motohashi N, Nakamura M, McKeel DW, Tabaton M, Lee HG, Smith MA, Perry G, Zhu X. The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. J Neuropathol Exp Neurol. 2012 Mar; 71(3):233-41. PMID: 22318126.
      Citations: 32     Fields:    Translation:HumansCells
    222. Perry GH, Xue Y, Smith RS, Meyer WK, Caliskan M, Yanez-Cuna O, Lee AS, Gutiérrez-Arcelus M, Ober C, Hollox EJ, Tyler-Smith C, Lee C. Evolutionary genetics of the human Rh blood group system. Hum Genet. 2012 Jul; 131(7):1205-16. PMID: 22367406.
      Citations: 4     Fields:    Translation:HumansCells
    223. Reed-Cossairt A, Zhu X, Lee HG, Reed C, Perry G, Petersen RB. Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome. Curr Gerontol Geriatr Res. 2012; 2012:929734. PMID: 22400025.
      Citations:    
    224. Bonda DJ, Liu G, Men P, Perry G, Smith MA, Zhu X. Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming! CNS Neurol Disord Drug Targets. 2012 Feb; 11(1):81-5. PMID: 22229318.
      Citations: 7     Fields:    Translation:HumansAnimals
    225. Santos RX, Correia SC, Zhu X, Lee HG, Petersen RB, Nunomura A, Smith MA, Perry G, Moreira PI. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease. Free Radic Res. 2012 Apr; 46(4):565-76. PMID: 22149654.
      Citations: 9     Fields:    Translation:HumansCells
    226. Zhu X, Castellani RJ, Ziats NP, Petersen RB, Gon Lee H, Perry G. Mark A. Smith: neurocytochemistry innovator. J Neurochem. 2012 Mar; 120(6):1139-40. PMID: 22268813.
      Citations:    Fields:    Translation:HumansCells
    227. Wang X, Yan MH, Fujioka H, Liu J, Wilson-Delfosse A, Chen SG, Perry G, Casadesus G, Zhu X. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum Mol Genet. 2012 May 01; 21(9):1931-44. PMID: 22228096.
      Citations: 136     Fields:    Translation:HumansAnimalsCells
    228. Perry G, Phelix CF, Nunomura A, Colom LV, Castellani RJ, Petersen RB, Lee HG, Zhu X. Untangling the vascular web from Alzheimer disease and oxidative stress. Can J Neurol Sci. 2012 Jan; 39(1):4. PMID: 22384486.
      Citations:    Fields:    Translation:Humans
    229. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases. Adv Exp Med Biol. 2012; 724:205-21. PMID: 22411245.
      Citations: 23     Fields:    Translation:HumansCells
    230. Perry G. Editorial: a new era for medicinal chemistry. Mini Rev Med Chem. 2012 Jan; 12(1):1. PMID: 22360667.
      Citations:    Fields:    
    231. Calderón-Garcidueñas L, Kavanaugh M, Block M, D'Angiulli A, Delgado-Chávez R, Torres-Jardón R, González-Maciel A, Reynoso-Robles R, Osnaya N, Villarreal-Calderon R, Guo R, Hua Z, Zhu H, Perry G, Diaz P. Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults. J Alzheimers Dis. 2012; 28(1):93-107. PMID: 21955814.
      Citations: 64     Fields:    Translation:HumansCellsPHPublic Health
    232. Perry GH, Melsted P, Marioni JC, Wang Y, Bainer R, Pickrell JK, Michelini K, Zehr S, Yoder AD, Stephens M, Pritchard JK, Gilad Y. Comparative RNA sequencing reveals substantial genetic variation in endangered primates. Genome Res. 2012 Apr; 22(4):602-10. PMID: 22207615.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    233. Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G, Zhu X. Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. J Neurochem. 2012 Feb; 120(3):419-29. PMID: 22077634.
      Citations: 99     Fields:    Translation:HumansCells
    234. Perry GH, Reeves D, Melsted P, Ratan A, Miller W, Michelini K, Louis EE, Pritchard JK, Mason CE, Gilad Y. A genome sequence resource for the aye-aye (Daubentonia madagascariensis), a nocturnal lemur from Madagascar. Genome Biol Evol. 2012; 4(2):126-35. PMID: 22155688.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    235. Colom LV, Castaneda MT, Hernandez S, Perry G, Jaime S, Touhami A. Intrahippocampal amyloid-ß (1-40) injections injure medial septal neurons in rats. Curr Alzheimer Res. 2011 Dec; 8(8):832-40. PMID: 22044024.
      Citations: 6     Fields:    Translation:Animals
    236. Wise-Scira O, Xu L, Kitahara T, Perry G, Coskuner O. Amyloid-ß peptide structure in aqueous solution varies with fragment size. J Chem Phys. 2011 Nov 28; 135(20):205101. PMID: 22128957.
      Citations: 18     Fields:    Translation:HumansCells
    237. Kudo W, Lee HP, Zou WQ, Wang X, Perry G, Zhu X, Smith MA, Petersen RB, Lee HG. Cellular prion protein is essential for oligomeric amyloid-ß-induced neuronal cell death. Hum Mol Genet. 2012 Mar 01; 21(5):1138-44. PMID: 22100763.
      Citations: 53     Fields:    Translation:AnimalsCells
    238. Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PLR, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radic Biol Med. 2012 Feb 01; 52(3):699-704. PMID: 22137893.
      Citations: 11     Fields:    Translation:HumansCells
    239. Ziats NP, Petersen RB, Lee HG, Castellani RJ, Perry G, Zhu X. Mark A. Smith, 1965-2010: consummate student of pathogenesis. Int J Clin Exp Pathol. 2011; 4(7):731-2. PMID: 22076176.
      Citations:    Fields:    Translation:HumansAnimals
    240. Castellani RJ, Gupta Y, Sheng B, Siedlak SL, Harris PL, Coller JM, Perry G, Lee HG, Tabaton M, Smith MA, Wang X, Zhu X. A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules. Lab Invest. 2011 Dec; 91(12):1777-86. PMID: 21968813.
      Citations: 12     Fields:    Translation:HumansCells
    241. Castellani RJ, Petersen RB, Lee HG, Zhu X, Perry G. Mark A. Smith: the scientist, the man. Int J Exp Pathol. 2011 Oct; 92(5):297-8. PMID: 21917030.
      Citations:    Fields:    
    242. Bonda DJ, Castellani RJ, Zhu X, Nunomura A, Lee HG, Perry G, Smith MA. A novel perspective on tau in Alzheimer's disease. Curr Alzheimer Res. 2011 Sep; 8(6):639-42. PMID: 21605042.
      Citations: 11     Fields:    Translation:HumansCells
    243. Liu Q, Xie F, Alvarado-Diaz A, Smith MA, Moreira PI, Zhu X, Perry G. Neurofilamentopathy in neurodegenerative diseases. Open Neurol J. 2011; 5:58-62. PMID: 21915226.
      Citations:    
    244. Stone JG, Siedlak SL, Tabaton M, Hirano A, Castellani RJ, Santocanale C, Perry G, Smith MA, Zhu X, Lee HG. The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies. J Neuropathol Exp Neurol. 2011 Jul; 70(7):578-87. PMID: 21666500.
      Citations: 7     Fields:    Translation:HumansCells
    245. Wang X, Su B, Liu W, He X, Gao Y, Castellani RJ, Perry G, Smith MA, Zhu X. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell. 2011 Oct; 10(5):807-23. PMID: 21615675.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    246. Valdez CM, Phelix CF, Smith MA, Perry G, Santamaria F. Modeling cholesterol metabolism by gene expression profiling in the hippocampus. Mol Biosyst. 2011 Jun; 7(6):1891-901. PMID: 21451815.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    247. Bonda DJ, Lee HG, Blair JA, Zhu X, Perry G, Smith MA. Role of metal dyshomeostasis in Alzheimer's disease. Metallomics. 2011 Mar; 3(3):267-70. PMID: 21298161.
      Citations: 46     Fields:    Translation:HumansAnimals
    248. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Res Rev. 2011 Apr; 10(2):264-73. PMID: 21262392.
      Citations: 57     Fields:    Translation:AnimalsCells
    249. Britton GB, Smith MA, Perry G, Sambamurti K, Jagannatha Rao KS. Drug discovery for neurodegenerative diseases: challenges and novel biochemical targets dedicated to the memory of Mark A. Smith for his inspiring contribution to Alzheimer's disease. J Alzheimers Dis. 2011; 24 Suppl 2:1-2. PMID: 21525570.
      Citations:    Fields:    Translation:Humans
    250. Stone JG, Casadesus G, Gustaw-Rothenberg K, Siedlak SL, Wang X, Zhu X, Perry G, Castellani RJ, Smith MA. Frontiers in Alzheimer's disease therapeutics. Ther Adv Chronic Dis. 2011 Jan 01; 2(1):9-23. PMID: 21743833.
      Citations:    
    251. Bonda DJ, Smith MA, Perry G, Lee HG, Wang X, Zhu X. The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention. Curr Pharm Des. 2011; 17(31):3374-80. PMID: 21902671.
      Citations: 11     Fields:    Translation:HumansCells
    252. Correia SC, Cardoso S, Santos RX, Carvalho C, Santos MS, Perry G, Smith MA, Moreira PI. New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection. Curr Pharm Des. 2011; 17(31):3381-9. PMID: 21902670.
      Citations: 11     Fields:    Translation:HumansCells
    253. Perry G, Zhu X. Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease. J Alzheimers Dis. 2011; 24(1):1-2. PMID: 21383496.
      Citations:    Fields:    Translation:Humans
    254. Ashford JW, Salehi A, Furst A, Bayley P, Frisoni GB, Jack CR, Sabri O, Adamson MM, Coburn KL, Olichney J, Schuff N, Spielman D, Edland SD, Black S, Rosen A, Kennedy D, Weiner M, Perry G. Imaging the Alzheimer brain. J Alzheimers Dis. 2011; 26 Suppl 3:1-27. PMID: 21971448.
      Citations: 6     Fields:    Translation:Humans
    255. Heath JE, Siedlak SL, Zhu X, Lee HG, Thakur A, Yan R, Perry G, Smith MA, Castellani RJ. Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology. 2010 Dec; 30(6):574-9. PMID: 20374499.
      Citations: 6     Fields:    Translation:HumansCells
    256. Perry GH, Marioni JC, Melsted P, Gilad Y. Genomic-scale capture and sequencing of endogenous DNA from feces. Mol Ecol. 2010 Dec; 19(24):5332-44. PMID: 21054605.
      Citations: 28     Fields:    Translation:Animals
    257. Stone AC, Battistuzzi FU, Kubatko LS, Perry GH, Trudeau E, Lin H, Kumar S. More reliable estimates of divergence times in Pan using complete mtDNA sequences and accounting for population structure. Philos Trans R Soc Lond B Biol Sci. 2010 Oct 27; 365(1556):3277-88. PMID: 20855302.
      Citations: 23     Fields:    Translation:AnimalsCells
    258. Castellani RJ, Nugent SL, Morrison AL, Zhu X, Lee HG, Harris PL, Bajic V, Sharma HS, Chen SG, Oettgen P, Perry G, Smith MA. CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease. J Neural Transm (Vienna). 2011 Jan; 118(1):23-6. PMID: 20972807.
      Citations: 3     Fields:    Translation:HumansCells
    259. Dwyer BE, Zacharski LR, Balestra DJ, Lerner AJ, Perry G, Zhu X, Smith MA. Potential role of iron in a Mediterranean-style diet. Arch Neurol. 2010 Oct; 67(10):1286-7; author reply 1287-8. PMID: 20937965.
      Citations:    Fields:    Translation:Humans
    260. Clark TA, Lee HP, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Casadesus G, Smith MA, Lee HG, Perry G. Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease. Int J Biomed Sci. 2010 Sep; 6(3):225-227. PMID: 21765811.
      Citations:    
    261. Correia SC, Carvalho C, Cardoso S, Santos RX, Santos MS, Oliveira CR, Perry G, Zhu X, Smith MA, Moreira PI. Mitochondrial preconditioning: a potential neuroprotective strategy. Front Aging Neurosci. 2010; 2. PMID: 20838473.
      Citations:    
    262. Luca F, Perry GH, Di Rienzo A. Evolutionary adaptations to dietary changes. Annu Rev Nutr. 2010 Aug 21; 30:291-314. PMID: 20420525.
      Citations: 33     Fields:    Translation:HumansAnimals
    263. Buxton GA, Siedlak SL, Perry G, Smith MA. Mathematical modeling of microtubule dynamics: insights into physiology and disease. Prog Neurobiol. 2010 Dec; 92(4):478-83. PMID: 20713128.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    264. Valdez CM, Smith MA, Perry G, Phelix CF, Santamaria F. Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers. Hippocampus. 2010 Aug; 20(8):902-5. PMID: 20054815.
      Citations: 11     Fields:    Translation:AnimalsCells
    265. Zou WQ, Puoti G, Xiao X, Yuan J, Qing L, Cali I, Shimoji M, Langeveld JP, Castellani R, Notari S, Crain B, Schmidt RE, Geschwind M, Dearmond SJ, Cairns NJ, Dickson D, Honig L, Torres JM, Mastrianni J, Capellari S, Giaccone G, Belay ED, Schonberger LB, Cohen M, Perry G, Kong Q, Parchi P, Tagliavini F, Gambetti P. Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Ann Neurol. 2010 Aug; 68(2):162-72. PMID: 20695009.
      Citations: 64     Fields:    Translation:Humans
    266. Guglielmotto M, Aragno M, Tamagno E, Vercellinatto I, Visentin S, Medana C, Catalano MG, Smith MA, Perry G, Danni O, Boccuzzi G, Tabaton M. AGEs/RAGE complex upregulates BACE1 via NF-?B pathway activation. Neurobiol Aging. 2012 Jan; 33(1):196.e13-27. PMID: 20638753.
      Citations: 50     Fields:    Translation:AnimalsCells
    267. Moreira PI, Santos RX, Zhu X, Lee HG, Smith MA, Casadesus G, Perry G. Autophagy in Alzheimer's disease. Expert Rev Neurother. 2010 Jul; 10(7):1209-18. PMID: 20586699.
      Citations: 11     Fields:    Translation:HumansCells
    268. Storace D, Cammarata S, Borghi R, Sanguineti R, Giliberto L, Piccini A, Pollero V, Novello C, Caltagirone C, Smith MA, Bossù P, Perry G, Odetti P, Tabaton M. Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment. Arch Neurol. 2010 Jul; 67(7):867-72. PMID: 20625095.
      Citations: 12     Fields:    Translation:Humans
    269. Nakamura M, Shishido N, Nunomura A, Smith MA, Perry G, Akutsu H, Hayashi T. Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid. Free Radic Res. 2010 Jul; 44(7):734-41. PMID: 20370566.
      Citations:    Fields:    Translation:HumansCells
    270. Lee HP, Zhu X, Casadesus G, Castellani RJ, Nunomura A, Smith MA, Lee HG, Perry G. Antioxidant approaches for the treatment of Alzheimer's disease. Expert Rev Neurother. 2010 Jul; 10(7):1201-8. PMID: 20586698.
      Citations: 31     Fields:    Translation:HumansAnimals
    271. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. Int J Clin Exp Pathol. 2010 Jun 25; 3(6):570-81. PMID: 20661404.
      Citations: 34     Fields:    Translation:HumansCells
    272. Moh CF, Siedlak SL, Tabaton M, Perry G, Castellani RJ, Smith MA. Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease. J Neurosci Methods. 2010 Jul 15; 190(2):244-7. PMID: 20580647.
      Citations: 2     Fields:    Translation:Humans
    273. Mondragón-Rodríguez S, Basurto-Islas G, Lee HG, Perry G, Zhu X, Castellani RJ, Smith MA. Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis. Expert Rev Neurother. 2010 May; 10(5):683-91. PMID: 20420489.
      Citations: 15     Fields:    Translation:HumansCells
    274. Poeggeler B, Sambamurti K, Siedlak SL, Perry G, Smith MA, Pappolla MA. A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. PLoS One. 2010 Apr 21; 5(4):e10206. PMID: 20421998.
      Citations: 9     Fields:    Translation:AnimalsCells
    275. Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, Smith MA. Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology. 2010 Sep-Oct; 59(4-5):290-4. PMID: 20394761.
      Citations: 95     Fields:    Translation:HumansAnimalsCells
    276. Lee HP, Zhu X, Liu G, Chen SG, Perry G, Smith MA, Lee HG. Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship. Cell Res. 2010 Apr; 20(4):397-9. PMID: 20357807.
      Citations: 6     Fields:    Translation:Humans
    277. Bonda DJ, Lee HP, Lee HG, Friedlich AL, Perry G, Zhu X, Smith MA. Novel therapeutics for Alzheimer's disease: an update. Curr Opin Drug Discov Devel. 2010 Mar; 13(2):235-46. PMID: 20205057.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    278. Bonda DJ, Wang X, Perry G, Smith MA, Zhu X. Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies. Drugs Aging. 2010 Mar 01; 27(3):181-92. PMID: 20210366.
      Citations: 23     Fields:    Translation:HumansCells
    279. Wang X, Perry G, Smith MA, Zhu X. Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons. Neurodegener Dis. 2010; 7(1-3):56-9. PMID: 20160460.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    280. Gustaw-Rothenberg K, Lerner A, Bonda DJ, Lee HG, Zhu X, Perry G, Smith MA. Biomarkers in Alzheimer's disease: past, present and future. Biomark Med. 2010 Feb; 4(1):15-26. PMID: 20387301.
      Citations: 23     Fields:    Translation:HumansCells
    281. Su B, Wang X, Bonda D, Perry G, Smith M, Zhu X. Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease? Mol Neurobiol. 2010 Jun; 41(2-3):87-96. PMID: 20101529.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    282. Avila J, Perry G, Martínez-Martín P. Prospects on the origin of Alzheimer's disease. J Alzheimers Dis. 2010; 20(2):669-72. PMID: 20505238.
      Citations: 2     Fields:    Translation:Humans
    283. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. J Alzheimers Dis. 2010; 20 Suppl 2:S401-12. PMID: 20463393.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    284. Nair NG, Perry G, Smith MA, Reddy VP. NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide. J Alzheimers Dis. 2010; 20(1):57-66. PMID: 20164601.
      Citations: 19     Fields:    Translation:HumansCells
    285. Borghi R, Piccini A, Barini E, Cirmena G, Guglielmotto M, Tamagno E, Fornaro M, Perry G, Smith MA, Garuti A, Tabaton M. Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease. J Alzheimers Dis. 2010; 22(3):771-5. PMID: 20847436.
      Citations: 7     Fields:    Translation:HumansCells
    286. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondria: the missing link between preconditioning and neuroprotection. J Alzheimers Dis. 2010; 20 Suppl 2:S475-85. PMID: 20463394.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    287. Smith MA, Zhu X, Tabaton M, Liu G, McKeel DW, Cohen ML, Wang X, Siedlak SL, Dwyer BE, Hayashi T, Nakamura M, Nunomura A, Perry G. Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis. 2010; 19(1):363-72. PMID: 20061651.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    288. Liu G, Men P, Perry G, Smith MA. Nanoparticle and iron chelators as a potential novel Alzheimer therapy. Methods Mol Biol. 2010; 610:123-44. PMID: 20013176.
      Citations: 23     Fields:    Translation:HumansCells
    289. Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease. Methods Mol Biol. 2010; 610:419-34. PMID: 20013193.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    290. Bonda DJ, Mailankot M, Stone JG, Garrett MR, Staniszewska M, Castellani RJ, Siedlak SL, Zhu X, Lee HG, Perry G, Nagaraj RH, Smith MA. Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Rep. 2010; 15(4):161-8. PMID: 20663292.
      Citations: 23     Fields:    Translation:HumansCells
    291. Bonda DJ, Wang X, Gustaw-Rothenberg KA, Perry G, Smith MA, Zhu X. Mitochondrial Drugs for Alzheimer Disease. Pharmaceuticals (Basel). 2009 Dec 23; 2(3):287-298. PMID: 20657666.
      Citations:    
    292. Cardoso S, Santos R, Correia S, Carvalho C, Zhu X, Lee HG, Casadesus G, Smith MA, Perry G, Moreira PI. Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets. Pharmaceuticals (Basel). 2009 Dec 23; 2(3):250-286. PMID: 27713238.
      Citations:    
    293. Nunomura A, Tamaoki T, Tanaka K, Motohashi N, Nakamura M, Hayashi T, Yamaguchi H, Shimohama S, Lee HG, Zhu X, Smith MA, Perry G. Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease. Neurobiol Dis. 2010 Mar; 37(3):731-7. PMID: 20034567.
      Citations: 29     Fields:    Translation:HumansCells
    294. Tabaton M, Perry G, Zhu X, Lee HG, Casadesus G, Smith MA. Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease. Am J Pathol. 2010 Feb; 176(2):540-1. PMID: 20019185.
      Citations:    Fields:    Translation:HumansAnimals
    295. Liu G, Men P, Perry G, Smith MA. Chapter 5 - Development of iron chelator-nanoparticle conjugates as potential therapeutic agents for Alzheimer disease. Prog Brain Res. 2009; 180:97-108. PMID: 20302830.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    296. Perry G, Moreira PI, Siedlak SL, Nunomura A, Zhu X, Smith MA. Natural oxidant balance in Parkinson disease. Arch Neurol. 2009 Dec; 66(12):1445. PMID: 20008647.
      Citations: 2     Fields:    Translation:Humans
    297. Perry GH, Pickrell JK. A rod cell marker of nocturnal ancestry. J Hum Evol. 2010 Feb; 58(2):207-10. PMID: 19942252.
      Citations: 2     Fields:    Translation:AnimalsCells
    298. Su B, Wang X, Lee HG, Tabaton M, Perry G, Smith MA, Zhu X. Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells. Neurosci Lett. 2010 Jan 14; 468(3):267-71. PMID: 19914335.
      Citations: 28     Fields:    Translation:HumansCells
    299. Lee HP, Casadesus G, Zhu X, Lee HG, Perry G, Smith MA, Gustaw-Rothenberg K, Lerner A. All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease. Expert Rev Neurother. 2009 Nov; 9(11):1615-21. PMID: 19903021.
      Citations: 22     Fields:    Translation:HumansAnimals
    300. Crain BJ, Terry RD, Perry G. 2009 award recipients--Peter C. Burger, MD, Pierluigi Gambetti, MD, and Nicholas K. Gonatas, MD. J Neuropathol Exp Neurol. 2009 Nov; 68(11):1244-6. PMID: 19901633.
      Citations:    Fields:    Translation:Humans
    301. Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta. 2010 Jan; 1802(1):2-10. PMID: 19853658.
      Citations: 139     Fields:    Translation:HumansAnimalsCells
    302. Moreira PI, Zhu X, Wang X, Lee HG, Nunomura A, Petersen RB, Perry G, Smith MA. Mitochondria: a therapeutic target in neurodegeneration. Biochim Biophys Acta. 2010 Jan; 1802(1):212-20. PMID: 19853657.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    303. Gustaw-Rothenberg KA, Siedlak SL, Bonda DJ, Lerner A, Tabaton M, Perry G, Smith MA. Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study. Exp Gerontol. 2010 Jan; 45(1):47-52. PMID: 19819324.
      Citations: 11     Fields:    Translation:Humans
    304. Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA, Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia. J Bioenerg Biomembr. 2009 Oct; 41(5):433-40. PMID: 19830532.
      Citations: 13     Fields:    Translation:HumansCells
    305. Su B, Wang X, Zheng L, Perry G, Smith MA, Zhu X. Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochim Biophys Acta. 2010 Jan; 1802(1):135-42. PMID: 19799998.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    306. Tabaton M, Zhu X, Perry G, Smith MA, Giliberto L. Signaling effect of amyloid-beta(42) on the processing of AbetaPP. Exp Neurol. 2010 Jan; 221(1):18-25. PMID: 19747481.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    307. Su B, Liu H, Wang X, Chen SG, Siedlak SL, Kondo E, Choi R, Takeda A, Castellani RJ, Perry G, Smith MA, Zhu X, Lee HG. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Mol Neurodegener. 2009 Jul 23; 4:32. PMID: 19627592.
      Citations: 16     Fields:    
    308. Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci. 2009 Jul 15; 29(28):9090-103. PMID: 19605646.
      Citations: 333     Fields:    Translation:HumansAnimalsCells
    309. Friedlich AL, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA. Treatment advances in Alzheimer's disease based on the oxidative stress model. F1000 Med Rep. 2009 Jul 08; 1. PMID: 20948726.
      Citations:    
    310. Dwyer BE, Stone ML, Gorman N, Sinclair PR, Perry G, Smith MA, Zhu X. Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease. Neurosci Lett. 2009 Sep 25; 461(3):302-5. PMID: 19539709.
      Citations: 2     Fields:    Translation:HumansAnimals
    311. Liu G, Men P, Perry G, Smith MA. Metal chelators coupled with nanoparticles as potential therapeutic agents for Alzheimer's disease. J Nanoneurosci. 2009 Jun 01; 1(1):42-55. PMID: 19936278.
      Citations:    
    312. Dwyer BE, Smith MA, Richardson SL, Perry G, Zhu X. Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease. Neurosci Lett. 2009 Aug 28; 460(2):180-4. PMID: 19477221.
      Citations: 5     Fields:    Translation:HumansCells
    313. Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J. Tau--an inhibitor of deacetylase HDAC6 function. J Neurochem. 2009 Jun; 109(6):1756-66. PMID: 19457097.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    314. Wang X, Su B, Zheng L, Perry G, Smith MA, Zhu X. The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Neurochem. 2009 May; 109 Suppl 1:153-9. PMID: 19393022.
      Citations: 95     Fields:    Translation:HumansAnimalsCells
    315. Bonda DJ, Evans TA, Santocanale C, Llosá JC, Viña J, Bajic V, Castellani RJ, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging (Albany NY). 2009 Apr; 1(4):382-8. PMID: 19946466.
      Citations: 36     Fields:    Translation:HumansCells
    316. Castellani RJ, Zhu X, Lee HG, Smith MA, Perry G. Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches. Int J Mol Sci. 2009 Mar; 10(3):1386-406. PMID: 19399255.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    317. Liu G, Men P, Kudo W, Perry G, Smith MA. Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease. Neurosci Lett. 2009 May 22; 455(3):187-90. PMID: 19429118.
      Citations: 22     Fields:    Translation:HumansCells
    318. Perry GH. The evolutionary significance of copy number variation in the human genome. Cytogenet Genome Res. 2008; 123(1-4):283-7. PMID: 19287166.
      Citations: 9     Fields:    Translation:HumansAnimals
    319. Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol. 2009 Jul; 118(1):151-66. PMID: 19271225.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    320. Rajendran R, Minqin R, Ynsa MD, Casadesus G, Smith MA, Perry G, Halliwell B, Watt F. A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease. Biochem Biophys Res Commun. 2009 Apr 24; 382(1):91-5. PMID: 19258010.
      Citations: 27     Fields:    Translation:Animals
    321. Perry GH, Dominy NJ. Evolution of the human pygmy phenotype. Trends Ecol Evol. 2009 Apr; 24(4):218-25. PMID: 19246118.
      Citations: 38     Fields:    Translation:Humans
    322. Dwyer BE, Zacharski LR, Balestra DJ, Lerner AJ, Perry G, Zhu X, Smith MA. Getting the iron out: phlebotomy for Alzheimer's disease? Med Hypotheses. 2009 May; 72(5):504-9. PMID: 19195795.
      Citations: 8     Fields:    Translation:Humans
    323. Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, Perry G. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radic Res. 2009 Feb; 43(2):156-64. PMID: 19160110.
      Citations: 24     Fields:    Translation:Animals
    324. Guglielmotto M, Aragno M, Autelli R, Giliberto L, Novo E, Colombatto S, Danni O, Parola M, Smith MA, Perry G, Tamagno E, Tabaton M. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem. 2009 Feb; 108(4):1045-56. PMID: 19196431.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    325. Perry G, Zhu X, Moreira PI, Smith MA. Altered redox balance in disease: can we change the new equilibria? Ann Neurol. 2009 Feb; 65(2):121-3. PMID: 19259960.
      Citations: 2     Fields:    Translation:HumansCells
    326. Rolston RK, Perry G, Zhu X, Castellani RJ, Dwyer BE, Lee HG, Petersen RB, Smith MA. Iron: A Pathological Mediator of Alzheimer Disease? Agro Food Ind Hi Tech. 2009 Jan 31; 19(6):33-36. PMID: 21544251.
      Citations:    
    327. Lee HG, Casadesus G, Nunomura A, Zhu X, Castellani RJ, Richardson SL, Perry G, Felsher DW, Petersen RB, Smith MA. The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse. Am J Pathol. 2009 Mar; 174(3):891-7. PMID: 19164506.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    328. Lee HP, Zhu X, Zhu X, Skidmore SC, Perry G, Sayre LM, Smith MA, Lee HG. The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells. J Neurochem. 2009 Mar; 108(6):1434-41. PMID: 19183271.
      Citations: 6     Fields:    Translation:HumansCells
    329. Tezapsidis N, Johnston JM, Smith MA, Ashford JW, Casadesus G, Robakis NK, Wolozin B, Perry G, Zhu X, Greco SJ, Sarkar S. Leptin: a novel therapeutic strategy for Alzheimer's disease. J Alzheimers Dis. 2009; 16(4):731-40. PMID: 19387109.
      Citations: 43     Fields:    Translation:HumansAnimals
    330. Reddy VP, Zhu X, Perry G, Smith MA. Oxidative stress in diabetes and Alzheimer's disease. J Alzheimers Dis. 2009; 16(4):763-74. PMID: 19387111.
      Citations: 54     Fields:    Translation:HumansAnimals
    331. Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. J Alzheimers Dis. 2009; 18(3):483-507. PMID: 19542630.
      Citations: 21     Fields:    Translation:Humans
    332. Castellani RJ, Lee HG, Siedlak SL, Nunomura A, Hayashi T, Nakamura M, Zhu X, Perry G, Smith MA. Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. J Alzheimers Dis. 2009; 18(2):447-52. PMID: 19584435.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    333. Lee HG, Casadesus G, Zhu X, Castellani RJ, McShea A, Perry G, Petersen RB, Bajic V, Smith MA. Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease. Neurochem Int. 2009 Feb; 54(2):84-8. PMID: 19114068.
      Citations: 46     Fields:    Translation:Humans
    334. Pallas M, Camins A, Smith MA, Perry G, Lee HG, Casadesus G. From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). J Alzheimers Dis. 2008 Dec; 15(4):615-24. PMID: 19096160.
      Citations: 45     Fields:    Translation:Animals
    335. Su B, Wang X, Nunomura A, Moreira PI, Lee HG, Perry G, Smith MA, Zhu X. Oxidative stress signaling in Alzheimer's disease. Curr Alzheimer Res. 2008 Dec; 5(6):525-32. PMID: 19075578.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    336. Ramiro-Puig E, Casadesús G, Lee HG, Zhu X, McShea A, Perry G, Pérez-Cano FJ, Smith MA, Castell M. Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress. Eur J Nutr. 2009 Feb; 48(1):54-61. PMID: 19043659.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    337. Lee HG, Zhu X, Casadesus G, Pallàs M, Camins A, O'Neill MJ, Nakanishi S, Perry G, Smith MA. The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival. Brain Res. 2009 Jan 16; 1249:244-50. PMID: 19026996.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    338. Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Rev Med Chem. 2008 Nov; 8(13):1395-406. PMID: 18991755.
      Citations: 28     Fields:    Translation:HumansAnimals
    339. Stone JG, Rolston RK, Ueda M, Lee HG, Richardson SL, Castellani RJ, Perry G, Smith MA. Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain. Int J Clin Exp Pathol. 2009; 2(3):267-74. PMID: 19079621.
      Citations: 2     Fields:    
    340. Obrenovich ME, Morales LA, Cobb CJ, Shenk JC, Méndez GM, Fischbach K, Smith MA, Qasimov EK, Perry G, Aliev G. Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation. J Cell Mol Med. 2009 May; 13(5):853-65. PMID: 19292735.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    341. Marlatt MW, Lucassen PJ, Perry G, Smith MA, Zhu X. Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies. J Alzheimers Dis. 2008 Oct; 15(2):199-210. PMID: 18953109.
      Citations: 23     Fields:    Translation:Humans
    342. Verrelli BC, Lewis CM, Stone AC, Perry GH. Different selective pressures shape the molecular evolution of color vision in chimpanzee and human populations. Mol Biol Evol. 2008 Dec; 25(12):2735-43. PMID: 18832077.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    343. Bryan KJ, Zhu X, Harris PL, Perry G, Castellani RJ, Smith MA, Casadesus G. Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease. Mol Neurodegener. 2008 Sep 11; 3:13. PMID: 18786268.
      Citations: 22     Fields:    
    344. Gelfand SL, Vento M, Sastre J, Lust WD, Smith MA, Perry G, Walsh M, Martin R. A new model of oxidative stress in rat pups. Neonatology. 2008; 94(4):293-9. PMID: 18784426.
      Citations: 3     Fields:    Translation:HumansAnimals
    345. Perry GH, Yang F, Marques-Bonet T, Murphy C, Fitzgerald T, Lee AS, Hyland C, Stone AC, Hurles ME, Tyler-Smith C, Eichler EE, Carter NP, Lee C, Redon R. Copy number variation and evolution in humans and chimpanzees. Genome Res. 2008 Nov; 18(11):1698-710. PMID: 18775914.
      Citations: 111     Fields:    Translation:HumansAnimalsCells
    346. Castellani RJ, Nunomura A, Lee HG, Perry G, Smith MA. Phosphorylated tau: toxic, protective, or none of the above. J Alzheimers Dis. 2008 Aug; 14(4):377-83. PMID: 18688087.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    347. Aliev G, Shenk JC, Fischbach K, Perry G. Stem cell niches as clinical targets: the future of anti-ischemic therapy? Nat Clin Pract Cardiovasc Med. 2008 Sep; 5(9):590-1. PMID: 18628773.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    348. Collingwood JF, Chong RK, Kasama T, Cervera-Gontard L, Dunin-Borkowski RE, Perry G, Pósfai M, Siedlak SL, Simpson ET, Smith MA, Dobson J. Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material. J Alzheimers Dis. 2008 Jun; 14(2):235-45. PMID: 18560134.
      Citations: 34     Fields:    Translation:Humans
    349. Castellani RJ, Lee HG, Zhu X, Perry G, Smith MA. Alzheimer disease pathology as a host response. J Neuropathol Exp Neurol. 2008 Jun; 67(6):523-31. PMID: 18520771.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    350. Su B, Wang X, Drew KL, Perry G, Smith MA, Zhu X. Physiological regulation of tau phosphorylation during hibernation. J Neurochem. 2008 Jun 01; 105(6):2098-108. PMID: 18284615.
      Citations: 20     Fields:    Translation:AnimalsCells
    351. Friedland RP, Tedesco JM, Wilson AC, Atwood CS, Smith MA, Perry G, Zagorski MG. Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies. J Biol Chem. 2008 Aug 15; 283(33):22550-6. PMID: 18505725.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    352. Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA. Sublethal RNA oxidation as a mechanism for neurodegenerative disease. Int J Mol Sci. 2008 May; 9(5):789-806. PMID: 19325784.
      Citations: 14     Fields:    
    353. Gustaw KA, Garrett MR, Lee HG, Castellani RJ, Zagorski MG, Prakasam A, Siedlak SL, Zhu X, Perry G, Petersen RB, Friedland RP, Smith MA. Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis. J Neurochem. 2008 Aug; 106(3):1350-6. PMID: 18485104.
      Citations: 21     Fields:    Translation:HumansAnimals
    354. Myung NH, Zhu X, Kruman II, Castellani RJ, Petersen RB, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes. Age (Dordr). 2008 Dec; 30(4):209-15. PMID: 19424844.
      Citations: 28     Fields:    
    355. Mondragón-Rodríguez S, Basurto-Islas G, Santa-Maria I, Mena R, Binder LI, Avila J, Smith MA, Perry G, García-Sierra F. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. Int J Exp Pathol. 2008 Apr; 89(2):81-90. PMID: 18336525.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    356. Ionita-Laza I, Perry GH, Raby BA, Klanderman B, Lee C, Laird NM, Weiss ST, Lange C. On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test. Genet Epidemiol. 2008 Apr; 32(3):273-84. PMID: 18228561.
      Citations: 33     Fields:    Translation:Humans
    357. Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. J Cell Mol Med. 2009 Feb; 13(2):320-33. PMID: 18373733.
      Citations: 33     Fields:    Translation:AnimalsCells
    358. Shah RS, Lee HG, Xiongwei Z, Perry G, Smith MA, Castellani RJ. Current approaches in the treatment of Alzheimer's disease. Biomed Pharmacother. 2008 Apr-May; 62(4):199-207. PMID: 18407457.
      Citations: 32     Fields:    Translation:HumansPHPublic Health
    359. Perry G, Zhu X, Babar AK, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Chen SG. Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies. Neurodegener Dis. 2008; 5(3-4):222-4. PMID: 18322396.
      Citations: 14     Fields:    Translation:Humans
    360. Gonzalez-Cuyar LF, Perry G, Miyajima H, Atwood CS, Riveros-Angel M, Lyons PF, Siedlak SL, Smith MA, Castellani RJ. Redox active iron accumulation in aceruloplasminemia. Neuropathology. 2008 Oct; 28(5):466-71. PMID: 18282164.
      Citations: 14     Fields:    Translation:HumansCells
    361. Moreira PI, Santos MS, Oliveira CR, Shenk JC, Nunomura A, Smith MA, Zhu X, Perry G. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS Neurol Disord Drug Targets. 2008 Feb; 7(1):3-10. PMID: 18289026.
      Citations: 40     Fields:    Translation:HumansAnimals
    362. Perry GH, Ben-Dor A, Tsalenko A, Sampas N, Rodriguez-Revenga L, Tran CW, Scheffer A, Steinfeld I, Tsang P, Yamada NA, Park HS, Kim JI, Seo JS, Yakhini Z, Laderman S, Bruhn L, Lee C. The fine-scale and complex architecture of human copy-number variation. Am J Hum Genet. 2008 Mar; 82(3):685-95. PMID: 18304495.
      Citations: 161     Fields:    Translation:HumansCells
    363. Chan HW, Liu T, Verdile G, Bishop G, Haasl RJ, Smith MA, Perry G, Martins RN, Atwood CS. Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity. Int J Clin Exp Med. 2008; 1(1):76-88. PMID: 19079689.
      Citations:    
    364. Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radic Biol Med. 2008 Apr 15; 44(8):1493-505. PMID: 18258207.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    365. Lee AS, Gutiérrez-Arcelus M, Perry GH, Vallender EJ, Johnson WE, Miller GM, Korbel JO, Lee C. Analysis of copy number variation in the rhesus macaque genome identifies candidate loci for evolutionary and human disease studies. Hum Mol Genet. 2008 Apr 15; 17(8):1127-36. PMID: 18180252.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    366. Casadesus G, Rolston RK, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA. Menopause, estrogen, and gonadotropins in Alzheimer's disease. Adv Clin Chem. 2008; 45:139-53. PMID: 18429496.
      Citations: 3     Fields:    Translation:Humans
    367. Thakur A, Siedlak SL, James SL, Bonda DJ, Rao A, Webber KM, Camins A, Pallàs M, Casadesus G, Lee HG, Bowser R, Raina AK, Perry G, Smith MA, Zhu X. Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease. Int J Clin Exp Pathol. 2008 Jan 01; 1(2):134-46. PMID: 18784806.
      Citations: 16     Fields:    
    368. Aliev G, Gasimov E, Obrenovich ME, Fischbach K, Shenk JC, Smith MA, Perry G. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease. Vasc Health Risk Manag. 2008; 4(3):721-30. PMID: 18827923.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    369. Perry G, Castellani RJ, Moreira PI, Lee HG, Zhu X, Smith MA. Pathology's new role: defining disease process and protective responses. Int J Clin Exp Pathol. 2008 Jan 01; 1(1):1-4. PMID: 18784818.
      Citations: 1     Fields:    
    370. Sayre LM, Perry G, Smith MA. Oxidative stress and neurotoxicity. Chem Res Toxicol. 2008 Jan; 21(1):172-88. PMID: 18052107.
      Citations: 149     Fields:    Translation:HumansAnimalsCells
    371. Webber KM, Casadesus G, Bowen RL, Perry G, Smith MA. Evidence for the role of luteinizing hormone in Alzheimer disease. Endocr Metab Immune Disord Drug Targets. 2007 Dec; 7(4):300-3. PMID: 18220951.
      Citations: 7     Fields:    Translation:HumansAnimals
    372. Castellani RJ, Perry G, Smith MA. The role of novel chitin-like polysaccharides in Alzheimer disease. Neurotox Res. 2007 Dec; 12(4):269-74. PMID: 18201954.
      Citations: 6     Fields:    Translation:HumansAnimals
    373. Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA, Perry G. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. CNS Neurol Disord Drug Targets. 2007 Dec; 6(6):411-23. PMID: 18220780.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    374. Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PG, Clark RS, Clarke SG, Clavé C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Dröge W, Dron M, Dunn WA, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, Fésüs L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, González-Estévez C, Gorski S, Gottlieb RA, Häussinger D, He YW, Heidenreich K, Hill JA, Høyer-Hansen M, Hu X, Huang WP, Iwasaki A, Jäättelä M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JA, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kovács AL, Kroemer G, Kuan CY, Kumar R, Kundu M, Landry J, Laporte M, Le W, Lei HY, Lenardo MJ, Levine B, Lieberman A, Lim KL, Lin FC, Liou W, Liu LF, Lopez-Berestein G, López-Otín C, Lu B, Macleod KF, Malorni W, Martinet W, Matsuoka K, Mautner J, Meijer AJ, Meléndez A, Michels P, Miotto G, Mistiaen WP, Mizushima N, Mograbi B, Monastyrska I, Moore MN, Moreira PI, Moriyasu Y, Motyl T, Münz C, Murphy LO, Naqvi NI, Neufeld TP, Nishino I, Nixon RA, Noda T, Nürnberg B, Ogawa M, Oleinick NL, Olsen LJ, Ozpolat B, Paglin S, Palmer GE, Papassideri I, Parkes M, Perlmutter DH, Perry G, Piacentini M, Pinkas-Kramarski R, Prescott M, Proikas-Cezanne T, Raben N, Rami A, Reggiori F, Rohrer B, Rubinsztein DC, Ryan KM, Sadoshima J, Sakagami H, Sakai Y, Sandri M, Sasakawa C, Sass M, Schneider C, Seglen PO, Seleverstov O, Settleman J, Shacka JJ, Shapiro IM, Sibirny A, Silva-Zacarin EC, Simon HU, Simone C, Simonsen A, Smith MA, Spanel-Borowski K, Srinivas V, Steeves M, Stenmark H, Stromhaug PE, Subauste CS, Sugimoto S, Sulzer D, Suzuki T, Swanson MS, Tabas I, Takeshita F, Talbot NJ, Tallóczy Z, Tanaka K, Tanaka K, Tanida I, Taylor GS, Taylor JP, Terman A, Tettamanti G, Thompson CB, Thumm M, Tolkovsky AM, Tooze SA, Truant R, Tumanovska LV, Uchiyama Y, Ueno T, Uzcátegui NL, van der Klei I, Vaquero EC, Vellai T, Vogel MW, Wang HG, Webster P, Wiley JW, Xi Z, Xiao G, Yahalom J, Yang JM, Yap G, Yin XM, Yoshimori T, Yu L, Yue Z, Yuzaki M, Zabirnyk O, Zheng X, Zhu X, Deter RL. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 2008 Feb; 4(2):151-75. PMID: 18188003.
      Citations: 1010     Fields:    Translation:HumansAnimalsCells
    375. Tamagno E, Guglielmotto M, Aragno M, Borghi R, Autelli R, Giliberto L, Muraca G, Danni O, Zhu X, Smith MA, Perry G, Jo DG, Mattson MP, Tabaton M. Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. J Neurochem. 2008 Feb; 104(3):683-95. PMID: 18005001.
      Citations: 99     Fields:    Translation:AnimalsCells
    376. Zhu X, Siedlak SL, Wang Y, Perry G, Castellani RJ, Cohen ML, Smith MA. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathol Appl Neurobiol. 2008 Aug; 34(4):457-65. PMID: 17995921.
      Citations: 29     Fields:    Translation:HumansCells
    377. Mondragón-Rodríguez S, Mena R, Binder LI, Smith MA, Perry G, García-Sierra F. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology. Neuropathol Appl Neurobiol. 2008 Feb; 34(1):62-75. PMID: 17971079.
      Citations: 11     Fields:    Translation:HumansCells
    378. Nakamura M, Shishido N, Nunomura A, Smith MA, Perry G, Hayashi Y, Nakayama K, Hayashi T. Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron. Biochemistry. 2007 Nov 06; 46(44):12737-43. PMID: 17929832.
      Citations: 39     Fields:    Translation:HumansCells
    379. Webber KM, Perry G, Smith MA, Casadesus G. The contribution of luteinizing hormone to Alzheimer disease pathogenesis. Clin Med Res. 2007 Oct; 5(3):177-83. PMID: 18056027.
      Citations: 11     Fields:    Translation:HumansAnimals
    380. Liu Q, Ju WK, Crowston JG, Xie F, Perry G, Smith MA, Lindsey JD, Weinreb RN. Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4580-9. PMID: 17898281.
      Citations: 40     Fields:    Translation:AnimalsCells
    381. Wang X, Su B, Perry G, Smith MA, Zhu X. Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radic Biol Med. 2007 Dec 15; 43(12):1569-73. PMID: 18037122.
      Citations: 28     Fields:    Translation:HumansCells
    382. Perry GH, Dominy NJ, Claw KG, Lee AS, Fiegler H, Redon R, Werner J, Villanea FA, Mountain JL, Misra R, Carter NP, Lee C, Stone AC. Diet and the evolution of human amylase gene copy number variation. Nat Genet. 2007 Oct; 39(10):1256-60. PMID: 17828263.
      Citations: 365     Fields:    Translation:HumansAnimals
    383. Zhu X, Su B, Wang X, Smith MA, Perry G. Causes of oxidative stress in Alzheimer disease. Cell Mol Life Sci. 2007 Sep; 64(17):2202-10. PMID: 17605000.
      Citations: 83     Fields:    Translation:HumansCells
    384. Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G. Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J Alzheimers Dis. 2007 Sep; 12(2):195-206. PMID: 17917164.
      Citations: 47     Fields:    Translation:HumansCells
    385. Hayashi T, Shishido N, Nakayama K, Nunomura A, Smith MA, Perry G, Nakamura M. Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide. Free Radic Biol Med. 2007 Dec 01; 43(11):1552-9. PMID: 17964426.
      Citations: 23     Fields:    Translation:HumansCells
    386. Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy. 2007 Nov-Dec; 3(6):614-5. PMID: 17786024.
      Citations: 46     Fields:    Translation:HumansCells
    387. Perry GH, Martin RD, Verrelli BC. Signatures of functional constraint at aye-aye opsin genes: the potential of adaptive color vision in a nocturnal primate. Mol Biol Evol. 2007 Sep; 24(9):1963-70. PMID: 17575304.
      Citations: 13     Fields:    Translation:Animals
    388. Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol. 2007 Jun; 66(6):525-32. PMID: 17549012.
      Citations: 45     Fields:    Translation:HumansCells
    389. Thakur A, Wang X, Siedlak SL, Perry G, Smith MA, Zhu X. c-Jun phosphorylation in Alzheimer disease. J Neurosci Res. 2007 Jun; 85(8):1668-73. PMID: 17455299.
      Citations: 25     Fields:    Translation:HumansCells
    390. Castellani RJ, Moreira PI, Liu G, Dobson J, Perry G, Smith MA, Zhu X. Iron: the Redox-active center of oxidative stress in Alzheimer disease. Neurochem Res. 2007 Oct; 32(10):1640-5. PMID: 17508283.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    391. Evans TA, Raina AK, Delacourte A, Aprelikova O, Lee HG, Zhu X, Perry G, Smith MA. BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease. Int J Med Sci. 2007 May 12; 4(3):140-5. PMID: 17505559.
      Citations: 26     Fields:    Translation:HumansCells
    392. Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, Smith MA. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Rev Neurother. 2007 May; 7(5):473-85. PMID: 17492899.
      Citations: 10     Fields:    Translation:HumansAnimals
    393. Petersen RB, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA, Zhu X. Signal transduction cascades associated with oxidative stress in Alzheimer's disease. J Alzheimers Dis. 2007 May; 11(2):143-52. PMID: 17522439.
      Citations: 30     Fields:    Translation:HumansCells
    394. Zhu X, Avila J, Perry G, Smith MA. Treating the lesions, not the disease. Am J Pathol. 2007 May; 170(5):1457-9. PMID: 17456753.
      Citations: 4     Fields:    Translation:HumansAnimals
    395. Perry GH. Risk assessment of transmission of bovine viral diarrhea virus (BVDV) in abattoir-derived in vitro produced embryos. Theriogenology. 2007 Jul 01; 68(1):38-55. PMID: 17462725.
      Citations: 1     Fields:    Translation:Animals
    396. Parker-Katiraee L, Carson AR, Yamada T, Arnaud P, Feil R, Abu-Amero SN, Moore GE, Kaneda M, Perry GH, Stone AC, Lee C, Meguro-Horike M, Sasaki H, Kobayashi K, Nakabayashi K, Scherer SW. Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution. PLoS Genet. 2007 May 04; 3(5):e65. PMID: 17480121.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    397. Casadesus G, Moreira PI, Nunomura A, Siedlak SL, Bligh-Glover W, Balraj E, Petot G, Smith MA, Perry G. Indices of metabolic dysfunction and oxidative stress. Neurochem Res. 2007 Apr-May; 32(4-5):717-22. PMID: 17342408.
      Citations: 9     Fields:    Translation:HumansCells
    398. Zhu X, Smith MA, Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. J Neurol Sci. 2007 Jun 15; 257(1-2):240-6. PMID: 17337008.
      Citations: 46     Fields:    Translation:HumansCells
    399. Casadesus G, Milliken EL, Webber KM, Bowen RL, Lei Z, Rao CV, Perry G, Keri RA, Smith MA. Increases in luteinizing hormone are associated with declines in cognitive performance. Mol Cell Endocrinol. 2007 Apr 15; 269(1-2):107-11. PMID: 17376589.
      Citations: 30     Fields:    Translation:Animals
    400. Wung JK, Perry G, Kowalski A, Harris PL, Bishop GM, Trivedi MA, Johnson SC, Smith MA, Denhardt DT, Atwood CS. Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. Curr Alzheimer Res. 2007 Feb; 4(1):67-72. PMID: 17316167.
      Citations: 22     Fields:    Translation:HumansCells
    401. Liu Q, Xie F, Rolston R, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Prevention and treatment of Alzheimer disease and aging: antioxidants. Mini Rev Med Chem. 2007 Feb; 7(2):171-80. PMID: 17305591.
      Citations: 15     Fields:    Translation:HumansAnimals
    402. Casadesus G, Smith MA, Basu S, Hua J, Capobianco DE, Siedlak SL, Zhu X, Perry G. Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. Mol Neurodegener. 2007 Jan 22; 2:2. PMID: 17241462.
      Citations: 13     Fields:    
    403. Lee HG, Zhu X, Castellani RJ, Nunomura A, Perry G, Smith MA. Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses. J Pharmacol Exp Ther. 2007 Jun; 321(3):823-9. PMID: 17229880.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    404. Perry GH, Tito RY, Verrelli BC. The evolutionary history of human and chimpanzee Y-chromosome gene loss. Mol Biol Evol. 2007 Mar; 24(3):853-9. PMID: 17218643.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    405. Nunomura A, Moreira PI, Takeda A, Smith MA, Perry G. Oxidative RNA damage and neurodegeneration. Curr Med Chem. 2007; 14(28):2968-75. PMID: 18220733.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    406. Gonzalez-Cuyar LF, Hunter B, Harris PL, Perry G, Smith MA, Castellani RJ. Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress. Redox Rep. 2007; 12(3):119-24. PMID: 17623518.
      Citations: 7     Fields:    Translation:Humans
    407. Bishop GM, Smith MA, LaManna JC, Wilson AC, Perry G, Atwood CS. Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox Rep. 2007; 12(6):257-66. PMID: 17961297.
      Citations: 5     Fields:    Translation:AnimalsCells
    408. Lee HG, Ueda M, Zhu X, Perry G, Smith MA. Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway? J Neurosci Res. 2006 Dec; 84(8):1856-61. PMID: 16998902.
      Citations: 17     Fields:    Translation:HumansCells
    409. Zhu X, Babar A, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Perry G, Chen SG. LRRK2 in Parkinson's disease and dementia with Lewy bodies. Mol Neurodegener. 2006 Nov 30; 1:17. PMID: 17137507.
      Citations: 18     Fields:    
    410. Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, González JR, Gratacòs M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME. Global variation in copy number in the human genome. Nature. 2006 Nov 23; 444(7118):444-54. PMID: 17122850.
      Citations: 1448     Fields:    Translation:Humans
    411. Fiegler H, Redon R, Andrews D, Scott C, Andrews R, Carder C, Clark R, Dovey O, Ellis P, Feuk L, French L, Hunt P, Kalaitzopoulos D, Larkin J, Montgomery L, Perry GH, Plumb BW, Porter K, Rigby RE, Rigler D, Valsesia A, Langford C, Humphray SJ, Scherer SW, Lee C, Hurles ME, Carter NP. Accurate and reliable high-throughput detection of copy number variation in the human genome. Genome Res. 2006 Dec; 16(12):1566-74. PMID: 17122085.
      Citations: 75     Fields:    Translation:HumansCells
    412. Zhu X, Siedlak SL, Smith MA, Perry G, Chen SG. LRRK2 protein is a component of Lewy bodies. Ann Neurol. 2006 Nov; 60(5):617-8; author reply 618-9. PMID: 16847950.
      Citations: 20     Fields:    Translation:HumansCells
    413. Zhu X, Lee HG, Perry G, Smith MA. Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta. 2007 Apr; 1772(4):494-502. PMID: 17142016.
      Citations: 91     Fields:    Translation:Humans
    414. Lee HG, Ueda M, Miyamoto Y, Yoneda Y, Perry G, Smith MA, Zhu X. Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease. Brain Res. 2006 Dec 08; 1124(1):1-4. PMID: 17070506.
      Citations: 15     Fields:    Translation:HumansCells
    415. Webber KM, Casadesus G, Atwood CS, Bowen RL, Perry G, Smith MA. Gonadotropins: a cohesive gender-based etiology of Alzheimer disease. Mol Cell Endocrinol. 2007 Jan 02; 260-262:271-5. PMID: 17052835.
      Citations: 7     Fields:    Translation:Humans
    416. Webber KM, Stocco DM, Casadesus G, Bowen RL, Atwood CS, Previll LA, Harris PL, Zhu X, Perry G, Smith MA. Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease. Mol Neurodegener. 2006 Oct 03; 1:14. PMID: 17018137.
      Citations: 11     Fields:    
    417. Smith MA, Perry G. Commentary on "Perspective on a pathogenesis and treatment of Alzheimer's disease." Therapeutic strategies for Alzheimer's disease: the need for a new era of innovation. Alzheimers Dement. 2006 Oct; 2(4):294-5. PMID: 19595903.
      Citations:    Fields:    
    418. Previll LA, Crosby ME, Castellani RJ, Bowser R, Perry G, Smith MA, Zhu X. Increased expression of p130 in Alzheimer disease. Neurochem Res. 2007 Apr-May; 32(4-5):639-44. PMID: 17006760.
      Citations: 9     Fields:    Translation:HumansCells
    419. Lam-Himlin D, Espey MG, Perry G, Smith MA, Castellani RJ. Malignant glioma progression and nitric oxide. Neurochem Int. 2006 Dec; 49(8):764-8. PMID: 16971023.
      Citations: 15     Fields:    Translation:Humans
    420. Zhu X, Raina AK, Perry G, Smith MA. Apoptosis in Alzheimer disease: a mathematical improbability. Curr Alzheimer Res. 2006 Sep; 3(4):393-6. PMID: 17017869.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    421. Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose! Am J Pathol. 2006 Sep; 169(3):738-9. PMID: 16936250.
      Citations: 5     Fields:    Translation:HumansAnimalsPHPublic Health
    422. Liu G, Men P, Harris PL, Rolston RK, Perry G, Smith MA. Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance. Neurosci Lett. 2006 Oct 09; 406(3):189-93. PMID: 16919875.
      Citations: 33     Fields:    Translation:Humans
    423. Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotox Res. 2006 Aug; 10(1):43-56. PMID: 17000469.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    424. Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA. Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol. 2006 Jul; 65(7):631-41. PMID: 16825950.
      Citations: 115     Fields:    Translation:HumansAnimalsCells
    425. Zhu X, Perry G, Moreira PI, Aliev G, Cash AD, Hirai K, Smith MA. Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease. J Alzheimers Dis. 2006 Jul; 9(2):147-53. PMID: 16873962.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    426. Franco S, Blasco MA, Siedlak SL, Harris PL, Moreira PI, Perry G, Smith MA. Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy? Alzheimers Dement. 2006 Jul; 2(3):164-8. PMID: 19595878.
      Citations: 18     Fields:    
    427. Sparks DL, Friedland R, Petanceska S, Schreurs BG, Shi J, Perry G, Smith MA, Sharma A, Derosa S, Ziolkowski C, Stankovic G. Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology. J Nutr Health Aging. 2006 Jul-Aug; 10(4):247-54. PMID: 16886094.
      Citations: 33     Fields:    Translation:HumansAnimalsPHPublic Health
    428. Forero DA, Casadesus G, Perry G, Arboleda H. Synaptic dysfunction and oxidative stress in Alzheimer's disease: emerging mechanisms. J Cell Mol Med. 2006 Jul-Sep; 10(3):796-805. PMID: 16989739.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    429. Freeman JL, Perry GH, Feuk L, Redon R, McCarroll SA, Altshuler DM, Aburatani H, Jones KW, Tyler-Smith C, Hurles ME, Carter NP, Scherer SW, Lee C. Copy number variation: new insights in genome diversity. Genome Res. 2006 Aug; 16(8):949-61. PMID: 16809666.
      Citations: 257     Fields:    Translation:HumansAnimals
    430. Lee HG, Zhu X, Takeda A, Perry G, Smith MA. Emerging evidence for the neuroprotective role of alpha-synuclein. Exp Neurol. 2006 Jul; 200(1):1-7. PMID: 16780837.
      Citations: 6     Fields:    Translation:HumansAnimals
    431. Moreira PI, Zhu X, Nunomura A, Smith MA, Perry G. Therapeutic options in Alzheimer's disease. Expert Rev Neurother. 2006 Jun; 6(6):897-910. PMID: 16784412.
      Citations: 12     Fields:    Translation:Humans
    432. Aliev G, Miller JP, Leifer DW, Obrenovich ME, Shenk JC, Smith MA, Lamanna JC, Perry G, Lust DW, Cohen AR. Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system. J Submicrosc Cytol Pathol. 2006 Jun-Sep; 38(2-3):85-91. PMID: 17784635.
      Citations: 1     Fields:    Translation:AnimalsCells
    433. Smith MA, Zhu X, Lee HG, Harris PL, Fortino AE, Perry G, Castellani RJ. Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy. Age (Dordr). 2006 Mar; 28(1):85-91. PMID: 23598681.
      Citations:    Fields:    
    434. Perry GH, Tchinda J, McGrath SD, Zhang J, Picker SR, Cáceres AM, Iafrate AJ, Tyler-Smith C, Scherer SW, Eichler EE, Stone AC, Lee C. Hotspots for copy number variation in chimpanzees and humans. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8006-11. PMID: 16702545.
      Citations: 109     Fields:    Translation:HumansAnimalsCells
    435. Lee HG, Perry G, Zhu X, Nunomura A, Smith MA. Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression". Free Radic Biol Med. 2006 Jul 15; 41(2):188-9. PMID: 16814097.
      Citations: 1     Fields:    Translation:Humans
    436. Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Sci Aging Knowledge Environ. 2006 May 03; 2006(8):pe10. PMID: 16672726.
      Citations: 8     Fields:    Translation:HumansCells
    437. Perry GH, Vivanco H, Holmes I, Gwozdz JM, Bourne J. No evidence of Mycobacterium avium subsp. paratuberculosis in in vitro produced cryopreserved embryos derived from subclinically infected cows. Theriogenology. 2006 Sep 15; 66(5):1267-73. PMID: 16672160.
      Citations:    Fields:    Translation:AnimalsCells
    438. Castellani RJ, Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathol. 2006 Jun; 111(6):503-9. PMID: 16718346.
      Citations: 45     Fields:    Translation:Humans
    439. Hasegawa T, Matsuzaki-Kobayashi M, Takeda A, Sugeno N, Kikuchi A, Furukawa K, Perry G, Smith MA, Itoyama Y. Alpha-synuclein facilitates the toxicity of oxidized catechol metabolites: implications for selective neurodegeneration in Parkinson's disease. FEBS Lett. 2006 Apr 03; 580(8):2147-52. PMID: 16567160.
      Citations: 16     Fields:    Translation:HumansCells
    440. Moreira PI, Zhu X, Lee HG, Honda K, Smith MA, Perry G. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease. Mech Ageing Dev. 2006 Jun; 127(6):501-6. PMID: 16516950.
      Citations: 4     Fields:    Translation:HumansCells
    441. Castellani RJ, Lee HG, Perry G, Smith MA. Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau. Am J Alzheimers Dis Other Demen. 2006 Mar-Apr; 21(2):126-30. PMID: 16634469.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    442. Casadesus G, Webber KM, Atwood CS, Pappolla MA, Perry G, Bowen RL, Smith MA. Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice. Biochim Biophys Acta. 2006 Apr; 1762(4):447-52. PMID: 16503402.
      Citations: 52     Fields:    Translation:Animals
    443. Strocchi P, Smith MA, Perry G, Tamagno E, Danni O, Pession A, Gaiba A, Dozza B. Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells. Neurobiol Aging. 2006 Nov; 27(11):1588-94. PMID: 16464517.
      Citations: 5     Fields:    Translation:HumansCells
    444. Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid beta: the alternate hypothesis. Curr Alzheimer Res. 2006 Feb; 3(1):75-80. PMID: 16472207.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    445. Moreira PI, Honda K, Zhu X, Nunomura A, Casadesus G, Smith MA, Perry G. Brain and brawn: parallels in oxidative strength. Neurology. 2006 Jan 24; 66(2 Suppl 1):S97-101. PMID: 16432155.
      Citations: 16     Fields:    Translation:HumansCells
    446. Zhu X, Lee HG, Moreira PI, Smith MA, Perry G. Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice". Free Radic Biol Med. 2006 Mar 01; 40(5):737-9. PMID: 16520226.
      Citations:    Fields:    Translation:HumansAnimalsCells
    447. Lee HG, Zhu X, Perry G, Smith MA. The fallacy of amyloid and cognition in Alzheimer's disease. Drugs Aging. 2006; 23(2):179. PMID: 16536639.
      Citations:    Fields:    Translation:HumansAnimals
    448. McCarroll SA, Hadnott TN, Perry GH, Sabeti PC, Zody MC, Barrett JC, Dallaire S, Gabriel SB, Lee C, Daly MJ, Altshuler DM. Common deletion polymorphisms in the human genome. Nat Genet. 2006 Jan; 38(1):86-92. PMID: 16468122.
      Citations: 278     Fields:    Translation:Humans
    449. Casadesus G, Garrett MR, Webber KM, Hartzler AW, Atwood CS, Perry G, Bowen RL, Smith MA. The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease. Drugs R D. 2006; 7(3):187-93. PMID: 16752944.
      Citations: 6     Fields:    Translation:Humans
    450. Moreira PI, Zhu X, Liu Q, Honda K, Siedlak SL, Harris PL, Smith MA, Perry G. Compensatory responses induced by oxidative stress in Alzheimer disease. Biol Res. 2006; 39(1):7-13. PMID: 16629160.
      Citations: 9     Fields:    Translation:HumansCells
    451. Perry G. Solving the insoluble. J Alzheimers Dis. 2006; 9(3 Suppl):301-4. PMID: 17004366.
      Citations: 2     Fields:    Translation:HumansCells
    452. Dwyer BE, Stone ML, Zhu X, Perry G, Smith MA. Heme deficiency in Alzheimer's disease: a possible connection to porphyria. J Biomed Biotechnol. 2006; 2006(3):24038. PMID: 17047301.
      Citations: 2     Fields:    
    453. Casadesus G, Puig ER, Webber KM, Atwood CS, Escuer MC, Bowen RL, Perry G, Smith MA. Targeting gonadotropins: an alternative option for Alzheimer disease treatment. J Biomed Biotechnol. 2006; 2006(3):39508. PMID: 17047306.
      Citations: 3     Fields:    
    454. Smith MA, Perry G, Zhu X, Haoudi A. Neurodegenerative diseases: mechanisms and therapies. J Biomed Biotechnol. 2006; 2006(3):47539. PMID: 17047307.
      Citations:    Fields:    
    455. Webber KM, Casadesus G, Zhu X, Obrenovich ME, Atwood CS, Perry G, Bowen RL, Smith MA. The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target. Curr Pharm Des. 2006; 12(6):691-7. PMID: 16472159.
      Citations: 5     Fields:    Translation:HumansAnimals
    456. Nunomura A, Honda K, Takeda A, Hirai K, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in neurodegenerative diseases. J Biomed Biotechnol. 2006; 2006(3):82323. PMID: 17047315.
      Citations: 28     Fields:    
    457. Perry GH, Verrelli BC, Stone AC. Molecular evolution of the primate developmental genes MSX1 and PAX9. Mol Biol Evol. 2006 Mar; 23(3):644-54. PMID: 16326750.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    458. Santa-María I, Hernández F, Smith MA, Perry G, Avila J, Moreno FJ. Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers. Mol Cell Biochem. 2005 Oct; 278(1-2):203-12. PMID: 16180106.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    459. Moreira PI, Honda K, Liu Q, Santos MS, Oliveira CR, Aliev G, Nunomura A, Zhu X, Smith MA, Perry G. Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Curr Alzheimer Res. 2005 Oct; 2(4):403-8. PMID: 16248845.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    460. Castellani RJ, Siedlak SL, Fortino AE, Perry G, Ghetti B, Smith MA. Chitin-like polysaccharides in Alzheimer's disease brains. Curr Alzheimer Res. 2005 Oct; 2(4):419-23. PMID: 16248847.
      Citations: 12     Fields:    Translation:HumansCells
    461. Webber KM, Raina AK, Marlatt MW, Zhu X, Prat MI, Morelli L, Casadesus G, Perry G, Smith MA. The cell cycle in Alzheimer disease: a unique target for neuropharmacology. Mech Ageing Dev. 2005 Oct; 126(10):1019-25. PMID: 15936057.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    462. Liu G, Garrett MR, Men P, Zhu X, Perry G, Smith MA. Nanoparticle and other metal chelation therapeutics in Alzheimer disease. Biochim Biophys Acta. 2005 Sep 25; 1741(3):246-52. PMID: 16051470.
      Citations: 29     Fields:    Translation:Humans
    463. Zhu X, Moreira PI, Smith MA, Perry G. Alzheimer's disease: an intracellular movement disorder? Trends Mol Med. 2005 Sep; 11(9):391-3. PMID: 16087404.
      Citations: 3     Fields:    Translation:Animals
    464. Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, Perry G. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathol. 2005 Sep; 110(3):232-8. PMID: 16096758.
      Citations: 21     Fields:    Translation:HumansCells
    465. Lin D, Lee HG, Liu Q, Perry G, Smith MA, Sayre LM. 4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chem Res Toxicol. 2005 Aug; 18(8):1219-31. PMID: 16097795.
      Citations: 47     Fields:    Translation:HumansCells
    466. Dwyer BE, Takeda A, Zhu X, Perry G, Smith MA. Ferric cycle activity and Alzheimer disease. Curr Neurovasc Res. 2005 Jul; 2(3):261-7. PMID: 16181119.
      Citations: 2     Fields:    Translation:HumansAnimals
    467. Casadesus G, Smith MA, Perry G. Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, and Luigi Puglielli. Alzheimers Dement. 2005 Jul; 1(1):51-2. PMID: 19595817.
      Citations:    Fields:    
    468. Zhu X, Smith MA, Perry G, Wang Y, Ross AP, Zhao HW, Lamanna JC, Drew KL. MAPKs are differentially modulated in arctic ground squirrels during hibernation. J Neurosci Res. 2005 Jun 15; 80(6):862-8. PMID: 15884016.
      Citations: 16     Fields:    Translation:AnimalsCells
    469. Lee HG, Castellani RJ, Zhu X, Perry G, Smith MA. Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective? Int J Exp Pathol. 2005 Jun; 86(3):133-8. PMID: 15910547.
      Citations: 19     Fields:    Translation:Humans
    470. Moreira PI, Smith MA, Zhu X, Nunomura A, Castellani RJ, Perry G. Oxidative stress and neurodegeneration. Ann N Y Acad Sci. 2005 Jun; 1043:545-52. PMID: 16037277.
      Citations: 34     Fields:    Translation:Humans
    471. Zhu X, Mei M, Lee HG, Wang Y, Han J, Perry G, Smith MA. P38 activation mediates amyloid-beta cytotoxicity. Neurochem Res. 2005 Jun-Jul; 30(6-7):791-6. PMID: 16187214.
      Citations: 17     Fields:    Translation:HumansCells
    472. Webber KM, Casadesus G, Marlatt MW, Perry G, Hamlin CR, Atwood CS, Bowen RL, Smith MA. Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis. Ann N Y Acad Sci. 2005 Jun; 1052:201-9. PMID: 16024763.
      Citations: 14     Fields:    Translation:Humans
    473. Ashford JW, Atwood CS, Blass JP, Bowen RL, Finch CE, Iqbal K, Joseph JA, Perry G. What is aging? What is its role in Alzheimer's disease? What can we do about it? J Alzheimers Dis. 2005 Jun; 7(3):247-53; discussion 255-62. PMID: 16006669.
      Citations: 6     Fields:    Translation:HumansAnimals
    474. Barbeito L, Chun J, Binder LI, Neto VM, Perry G, Scazzochio C, Violini G. The end of a Chilean institute. Science. 2005 May 06; 308(5723):792-3. PMID: 15879193.
      Citations:    Fields:    
    475. Reddy VP, Garrett MR, Perry G, Smith MA. Carnosine: a versatile antioxidant and antiglycating agent. Sci Aging Knowledge Environ. 2005 May 04; 2005(18):pe12. PMID: 15872311.
      Citations: 19     Fields:    Translation:HumansCells
    476. Smith MA, Nunomura A, Lee HG, Zhu X, Moreira PI, Avila J, Perry G. Chronological primacy of oxidative stress in Alzheimer disease. Neurobiol Aging. 2005 May; 26(5):579-80. PMID: 15708430.
      Citations: 14     Fields:    Translation:Humans
    477. Webber KM, Casadesus G, Perry G, Atwood CS, Bowen R, Smith MA. Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis. Alzheimer Dis Assoc Disord. 2005 Apr-Jun; 19(2):95-9. PMID: 15942328.
      Citations: 8     Fields:    Translation:HumansAnimals
    478. Moreira PI, Oliveira CR, Santos MS, Nunomura A, Honda K, Zhu X, Smith MA, Perry G. A second look into the oxidant mechanisms in Alzheimer's disease. Curr Neurovasc Res. 2005 Apr; 2(2):179-84. PMID: 16181112.
      Citations: 1     Fields:    Translation:HumansCells
    479. Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA. Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends Mol Med. 2005 Apr; 11(4):164-9. PMID: 15823754.
      Citations: 54     Fields:    Translation:HumansCells
    480. Liu Q, Smith MA, Avilá J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, Ghanbari HA, Siedlak SL, Harris PL, Sayre LM, Perry G. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radic Biol Med. 2005 Mar 15; 38(6):746-54. PMID: 15721985.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    481. Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem. 2005 Jun 03; 280(22):20978-86. PMID: 15767256.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    482. Webber KM, Smith MA, Lee HG, Harris PL, Moreira P, Perry G, Zhu X. Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease. J Neurosci Res. 2005 Feb 15; 79(4):554-60. PMID: 15635602.
      Citations: 9     Fields:    Translation:HumansCells
    483. Zhu X, Perry G, Smith MA. Insulin signaling, diabetes mellitus and risk of Alzheimer disease. J Alzheimers Dis. 2005 Feb; 7(1):81-4.