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George Perry

TitleDr.
Faculty RankProfessor
InstitutionUniversity of Texas at San Antonio
DepartmentCollege of Sciences
AddressCollege of Sciences
One UTSA Circle
San Antonio TX 78249
Phone(210) 458-8660
Fax(210) 458-5658
ORCID ORCID Icon0000-0002-6547-0172 Additional info
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    Other Positions
    TitleAffiliate Professor
    InstitutionUniversity of Alaska Fairbanks
    DepartmentChemistry and Biochemistry


    Collapse Biography 
    Collapse awards and honors
    2001Distinguished American of Portuguese Ancestry, Portuguese-American Historical and Research Foundation
    2003Hall of Fame, Lompoc High School Alumni Association
    2003Mensch Award , Alzheimer Research Forum
    2003Top 20 Most-Cited Authors in Alzheimer’s Disease, Essential Science Indicators
    2004 - 2007100 Most-Cited Scientists in Neuroscience and Behavior of the Decade, In-cites
    2004Community Service Award, Cleveland Area Chapter of the Alzheimer’s Association
    2007Doctorado Honoris Causa (Hon. D.) , Universidad Arturo Prat, Iquique, Chile
    2007Top 25 Lab Heads in Free Radical Research, Free Radical Lab Registry
    2007Zenith Fellow, Alzheimer’s Association
    2008Denham Harman Research Award, American Aging Association
    2008ISI Highly Cited.com, Neuroscience
    2009Foreign Corresponding Member, Royal Spanish Academy of Sciences
    2009Top 100 Alzheimer’s Disease Investigators
    2010Alzheimer Award / Alzheimer Medal, Journal of Alzheimer’s Disease
    2010Corresponding Member, Mexican Academy of Sciences
    2010Distinguished Professional Mentor Award, Society for the Advancement of Chicanos and Native American Scientists (SACNAS)
    2011Alzheimer Award / Alzheimer Medal, Journal of Alzheimer’s Disease
    2011Chartered Biologist (CBiol), Society of Biology
    2011Fellow, Linnean Society of London
    2011Fellow, Microscopy Society of America
    2011Fellow, Royal College of Pathologists
    2011Fellow, Royal Society of Biology
    2011Fellow, Royal Society of Chemistry
    2011Foreign Corresponding Member, Academy of Sciences of Lisbon
    2011National Honor Plaque of Panama for Exceptional Contribution to “Neuroscience", Secretar?a nacional de Ciencia, Technolog?a e Innovación (SENACYT)
    2011Senior Investigator Award, International College of Geriatric Psychoneuropharmacology (ICGP)
    2011Top 20 Alzheimer’s Disease Authors,
    2012Charter and Life Member, Phi Kappa Phi
    2012Chartered Chemist (CChem), Royal Society of Chemistry
    2012Chartered Scientist (CSci), Royal Society of Biology
    2012Fulbright Senior Scholar Specialist Program, US Deparment of State
    2012Gente Notavel(Notable People), Azorean Spirit, SATA Inflight Magazine
    2012Notaveis dos Azores, Governo dos Azores
    2012Outstanding Service Award, International Conference on Research in Applied Computation Symposium
    2012Scientist of the Year, Portuguese Tribune
    2013Distinguished Chair in Neurobiology, Semmes Foundation
    2013Leading Expert-Alzheimer Disease, Expertscape
    2013Martin Goland Award, Sigma XI, Alamo Chapter
    2014Fellow, Royal Microscopical Society, (FRMS)
    2014Fellow, Royal Society of the Encouragement of Arts, Manufactures and Commerce
    2014UDAAN-Lifetime Achievement Award, International Journal of Humanities, Engineering and Pharmaceutical Sciences..., India
    2015Distinguished Fellow and President, International Engineering and Technology Institute
    2015Fellow, Association of Biotechnology and Pharmacy (India), FABAP
    2016Fellow, Texas Academy of Sciences
    2016Lifetime Achievement, World Automation Congress
    2016Semmes Distinguished University Chair in Neurobiology, Semmes Foundation
    2017Albert Nelson Marquis Lifetime Achievement Award, Marquis Who''s Who
    2017Annual Scientific Award, International Engineering and Technology Institute
    2017Chartered Science Teacher (CSciTeach), Royal Society of Biology
    2017Fellow, World Academy of Medical Sciences
    2017Member, EU Academy of Sciences
    2018Counselors, Conselho da Diáspora Portuguesa
    2018Distinction of Excellence Award in Alzheimer''s Disease Research, Alzheimer Association:
    2018Honorable Director, Global Listening Centre
    2020Texas Distinguished Scientist, Texas Academy of Sciences
    2021Rous-Whipple Award, American Society for Investigative Pathology
    2020Distinguished Member, Japanese Society of Neurology
    2022Fellow, Sigma Xi
    2021Scientist of the Year, BioPub
    2022Research and Education Lifetime Achievement Award, Global Association for the Study of Neurodegenerative Diseases
    2022Best Scientist, Research.com
    2023Best Scientist, Research.com
    2024Best Scientist, Research.com
    2025Best Scientist, Research.com
    2025Academy of Distinguished Researchers, UT San Antonio
    2024Golden Axon Leadership Award, Society Brain Mapping and Therapeutics

    Collapse Overview 
    Collapse overview
    George Perry is former dean of the College of Sciences and the Semmes Foundation Distinguished University Chair in Neurobiology at The University of Texas at San Antonio. Dr. Perry is recognized in the field of Alzheimer’s disease research particularly for his work on oxidative metabolism.

    Dr. Perry is distinguished as one of the top Alzheimer’s disease researchers with over 1,000 publications, and one of the top 100 most-cited scientists in neuroscience and behavior (Over 116,000 citations, H=170), as well as the Expertscape Leading Expert in Alzheimer’s disease. Perry serves as editor for numerous journals and is Editor-in-Chief for the Journal of Alzheimer's Disease. He is a fellow of the American Association for the Advancement of Sciences, International Engineering and Technology Institute, Texas Academy of Sciences, and Microscopy Society of America, a Fulbright Senior Specialist, as well as a member of the Dana Alliance for Brain Initiatives. Perry is also recognized internationally: he is a Foreign Member of the Spanish Royal Academy of Sciences, the Academy of Science Lisbon, and the Mexican National Academy of Sciences. He is also a recipient of the National Plaque of Honor from the Republic of Panama Ministry of Science and Technology., Rous-Whipple award from American Society for Investigative Pathology, Distinguished Member of the Japanese Society of Neurology.

    Dr. Perry received his BA in Zoology from the University of California, Santa Barbara followed by his Ph.D. in Marine Biology from Scripps Institution of Oceanography. He then received a postdoctoral fellowship in the Department of Cell Biology at Baylor College of Medicine where he laid the foundation for his observations of abnormalities in cell structures.

    Collapse Research 
    Collapse research activities and funding
    K04AG000415     (PERRY, GEORGE)Apr 1, 1988 - Aug 31, 1993
    NIH
    AMYLOID PRECURSOR IN ALZHEIMER DISEASE
    Role: Principal Investigator
    R01AG007552     (PERRY, GEORGE)Apr 1, 1988 - Mar 31, 1994
    NIH
    AMYLOID PRECURSOR IN ALZHEIMER DISEASE
    Role: Principal Investigator
    R01AG009287     (PERRY, GEORGE)Sep 1, 1990 - Nov 30, 2000
    NIH
    NEUROFIBRILLARY PATHOLOGY IN ALZHEIMER DISEASE
    Role: Principal Investigator
    G12RR013646     (TSIN, ANDREW T C)Sep 30, 1998 - Jun 30, 2015
    NIH
    RCMI Center for Interdiscplinary Health Research CIHR
    Role: Co-Investigator
    G12MD007591     (PERRY, GEORGE)Sep 30, 1998 - Jun 30, 2017
    NIH
    RCMI Center for Interdiscplinary Health Research CIHR
    Role: Co-Investigator

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Xiyang Y, Gao J, Ding M, Ren X, Appleby BS, Leverenz JB, Miyagi M, Pillai JA, Perry G, Wang X. Exacerbated mitochondrial dynamic abnormalities without evident tau pathology in rapidly progressive Alzheimer's disease. J Alzheimers Dis. 2024 Dec; 102(4):1074-1083. PMID: 39584307.
      Citations:    Fields:    
    2. Castellani RJ, Jamshidi P, Plascencia-Villa G, Perry G. The Amyloid Cascade Hypothesis: A Conclusion in Search of Support. Am J Pathol. 2024 Nov 10. PMID: 39532243.
      Citations:    Fields:    
    3. Elbatrawy AA, Ademoye TA, Alnakhala H, Tripathi A, Plascencia-Villa G, Zhu X, Perry G, Dettmer U, Fortin JS. Exploring the rhodanine universe: Design and synthesis of fluorescent rhodanine-based derivatives as anti-fibrillar and anti-oligomer agents against a-synuclein and 2N4R tau. Bioorg Med Chem. 2024 Dec 15; 116:117990. PMID: 39550891.
      Citations:    Fields:    Translation:HumansCells
    4. Wang W, Wang Q, Qi X, Gurney M, Perry G, Volkow ND, Davis PB, Kaelber DC, Xu R. Associations of semaglutide with first-time diagnosis of Alzheimer's disease in patients with type 2 diabetes: Target trial emulation using nationwide real-world data in the US. Alzheimers Dement. 2024 Dec; 20(12):8661-8672. PMID: 39445596.
      Citations:    Fields:    
    5. Ganegamage SK, Ademoye TA, Patel H, Alnakhala H, Tripathi A, Nguyen CCD, Pham K, Plascencia-Villa G, Zhu X, Perry G, Tian S, Dettmer U, Lasagna-Reeves C, Fortin JS. Evaluation of Alpha-Synuclein and Tau Antiaggregation Activity of Urea and Thiourea-Based Small Molecules for Neurodegenerative Disease Therapeutics. ACS Chem Neurosci. 2024 Nov 06; 15(21):3915-3931. PMID: 39436010.
      Citations:    Fields:    Translation:HumansCells
    6. Bathini P, Brai E, Balin BJ, Bimler L, Corry DB, Devanand DP, Doty RL, Ehrlich GD, Eimer WA, Fulop T, Hahn DL, Hammond CJ, Infanti J, Itzhaki R, Lathe R, Little CS, McLeod R, Moein ST, Nelson AR, Perry G, Shemesh OA, Tanzi RE, Webley WC, Schultek NM, Alberi Auber L. Sensory Dysfunction, Microbial Infections, and Host Responses in Alzheimer's Disease. J Infect Dis. 2024 Sep 10; 230(Supplement_2):S150-S164. PMID: 39255393.
      Citations:    Fields:    Translation:Humans
    7. Woodward M, Bennett DA, Rundek T, Perry G, Rudka T. The relationship between hippocampal changes in healthy aging and Alzheimer's disease: a systematic literature review. Front Aging Neurosci. 2024; 16:1390574. PMID: 39210976.
      Citations:    
    8. Yassaghi Y, Nazerian Y, Ghasemi M, Nazerian A, Sayehmiri F, Perry G, Gholami Pourbadie H. Microglial modulation as a therapeutic strategy in Alzheimer's disease: Focus on microglial preconditioning approaches. J Cell Mol Med. 2024 Aug; 28(15):e18554. PMID: 39103747.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    9. Plascencia-Villa G, Castellani RJ, Perry G. Central role of brain regulatory T cells in the inflammatory cascade in Alzheimer's disease. Proc Natl Acad Sci U S A. 2024 Aug 06; 121(32):e2412255121. PMID: 39074294.
      Citations:    Fields:    Translation:HumansAnimalsCells
    10. Avila J, Marco J, Plascencia-Villa G, Bajic VP, Perry G. Could there be an experimental way to link consciousness and quantum computations of brain microtubules? Front Neurosci. 2024; 18:1430432. PMID: 38979125.
      Citations:    
    11. H?ilund-Carlsen PF, Alavi A, Barrio JR, Castellani RJ, Costa T, Herrup K, Kepp KP, Neve RL, Perry G, Revheim ME, Robakis NK, Sensi SL, Vissel B. Donanemab, another anti-Alzheimer's drug with risk and uncertain benefit. Ageing Res Rev. 2024 Aug; 99:102348. PMID: 38830549.
      Citations: 3     Fields:    Translation:Humans
    12. H?ilund-Carlsen PF, Alavi A, Castellani RJ, Neve RL, Perry G, Revheim ME, Barrio JR. Alzheimer's Amyloid Hypothesis and Antibody Therapy: Melting Glaciers? Int J Mol Sci. 2024 Mar 31; 25(7). PMID: 38612701.
      Citations: 2     Fields:    Translation:Humans
    13. Everett J, Brooks J, Tjendana Tjhin V, Lermyte F, Hands-Portman I, Plascencia-Villa G, Perry G, Sadler PJ, O'Connor PB, Collingwood JF, Telling ND. Label-Free In Situ Chemical Characterization of Amyloid Plaques in Human Brain Tissues. ACS Chem Neurosci. 2024 04 03; 15(7):1469-1483. PMID: 38501754.
      Citations: 1     Fields:    Translation:Humans
    14. Diaz-Lasprilla AM, McKee M, Jimenez-Vergara AC, Ravi S, Bellamy D, Ortega W, Crosby CO, Steele J, Plascencia-Villa G, Perry G, Munoz-Pinto DJ. Fabrication and Characterization of Quad-Component Bioinspired Hydrogels to Model Elevated Fibrin Levels in Central Nervous Tissue Scaffolds. Gels. 2024 Mar 17; 10(3). PMID: 38534621.
      Citations:    
    15. Garc?a-Carlos CA, Basurto-Islas G, Perry G, Mondrag?n-Rodr?guez S. Meta-Analysis in Transgenic Alzheimer's Disease Mouse Models Reveals Opposite Brain Network Effects of Amyloid-? and Phosphorylated Tau Proteins. J Alzheimers Dis. 2024; 99(2):595-607. PMID: 38669540.
      Citations:    Fields:    Translation:HumansAnimalsCells
    16. Perry G. JAD's Glorious 100 Volumes. J Alzheimers Dis. 2024; 100(s1):S1. PMID: 39031374.
      Citations:    Fields:    Translation:Humans
    17. Khan AH, Ijaz E, Ubaid B, Eddaki I, Edhi M, Shah MN, Perry G. Analysis of Alzheimer's Disease-Related Mortality Rates Among the Elderly Populations Across the United States: An Analysis of Demographic and Regional Disparities from 1999 to 2020. Curr Alzheimer Res. 2024; 21(6):384-394. PMID: 39444182.
      Citations:    Fields:    Translation:Humans
    18. Yazdanpanah N, Sedikides C, Ochs HD, Camargo CA, Darmstadt GL, Cerda A, Cauda V, Peters GJ, Sellke F, Wong ND, Comini E, Jimeno AR, Glover V, Hatziargyriou N, Vincenot CE, Bordas SPA, Rao IM, Abolhassani H, Gharehpetian GB, Weiskirchen R, Gupta M, Chandel SS, Olusanya BO, Cheson B, Pomponio A, Tanzer M, Myles PS, Ma WX, Bella F, Ghavami S, Moein Moghimi S, Pratico D, Hernandez AM, Martinez-Urbistondo M, Urbistondo DM, Fereshtehnejad SM, Ali I, Kimura S, Wallace Hayes A, Cai W, Ernest CKJ, Thomas S, Rahimi K, Sorooshian A, Schreiber M, Kato K, Luong JHT, Pluchino S, Lozano AM, Seymour JF, Kosik KS, Hofmann SG, McIntyre RS, Perc M, Leemans A, Klein RS, Ogino S, Wlezien C, Perry G, Nieto JJ, Levin L, Klionsky DJ, Mobasher B, Dorigo T, Rezaei N. Global Challenges After a Global Challenge: Lessons Learned from the COVID-19 Pandemic. Adv Exp Med Biol. 2024; 1457:1-31. PMID: 39283418.
      Citations:    Fields:    Translation:HumansPHPublic Health
    19. Pappolla MA, Martins RN, Poeggeler B, Omar RA, Perry G. Oxidative Stress in Alzheimer's Disease: The Shortcomings of Antioxidant Therapies. J Alzheimers Dis. 2024; 101(s1):S155-S178. PMID: 39422961.
      Citations:    Fields:    Translation:HumansAnimals
    20. Correia SC, Perry G, Moreira PI. Fueling Alzheimer's Disease: Where Does Immunometabolism Stand? J Alzheimers Dis. 2024; 100(s1):S363-S385. PMID: 39177607.
      Citations:    Fields:    Translation:HumansAnimalsCells
    21. Moreira PI, Avila J, Galimberti D, Pappolla MA, Plascencia-Villa G, Sorensen AA, Zhu X, Perry G. Therapeutic Trials in Alzheimer's Disease: Where Are We Now? J Alzheimers Dis. 2024; 101(s1):S1-S2. PMID: 39422966.
      Citations:    Fields:    
    22. Butler T, Tey SR, Galvin JE, Perry G, Bowen RL, Atwood CS. Endocrine Dyscrasia in the Etiology and Therapy of Alzheimer's Disease. J Alzheimers Dis. 2024; 101(3):705-713. PMID: 39240636.
      Citations:    Fields:    Translation:HumansAnimals
    23. Pappolla MA, Wu P, Fang X, Poeggeler B, Sambamurti K, Wisniewski T, Perry G. Stem Cell Interventions in Neurology: From Bench to Bedside. J Alzheimers Dis. 2024; 101(s1):S395-S416. PMID: 39422938.
      Citations:    Fields:    Translation:HumansAnimalsCells
    24. Liang J, LaFleur B, Hussainy S, Perry G. Gene Co-Expression Analysis of Multiple Brain Tissues Reveals Correlation of FAM222A Expression with Multiple Alzheimer's Disease-Related Genes. J Alzheimers Dis. 2024; 99(s2):S249-S263. PMID: 37092222.
      Citations:    Fields:    Translation:Humans
    25. Gao J, Leinonen H, Wang EJ, Ding M, Perry G, Palczewski K, Wang X. Sex-Specific Early Retinal Dysfunction in Mutant TDP-43 Transgenic Mice. J Alzheimers Dis. 2024; 97(2):927-937. PMID: 38143367.
      Citations: 1     Fields:    Translation:HumansAnimals
    26. Perry G. Living Up to the Promise of Preventing Dementia. J Alzheimers Dis. 2024; 98(1):337. PMID: 38339938.
      Citations:    Fields:    Translation:Humans
    27. H?ilund-Carlsen PF, Alavi A, Barrio JR, Castellani RJ, Costa T, Herrup K, Kepp KP, Neve RL, Perry G, Revheim ME, Robakis NK, Sensi SL, Vissel B. Revision of Alzheimer's diagnostic criteria or relocation of the Potemkin village. Ageing Res Rev. 2024 01; 93:102173. PMID: 38104639.
      Citations: 1     Fields:    Translation:Humans
    28. Ramirez E, Ganegamage SK, Min S, Patel H, Ogunware A, Plascencia-Villa G, Alnakhala H, Shimanaka K, Tripathi A, Wang KW, Zhu X, Rochet JC, Kuo MH, Counts SE, Perry G, Dettmer U, Lasagna-Reeves CA, Fortin JS. Evaluation of N- and O-Linked Indole Triazines for a Dual Effect on a-Synuclein and Tau Aggregation. ACS Chem Neurosci. 2023 11 01; 14(21):3913-3927. PMID: 37818657.
      Citations: 1     Fields:    Translation:Humans
    29. Lea AJ, Clark AG, Dahl AW, Devinsky O, Garcia AR, Golden CD, Kamau J, Kraft TS, Lim YAL, Martins DJ, Mogoi D, Pajukanta P, Perry GH, Pontzer H, Trumble BC, Urlacher SS, Venkataraman VV, Wallace IJ, Gurven M, Lieberman DE, Ayroles JF. Applying an evolutionary mismatch framework to understand disease susceptibility. PLoS Biol. 2023 09; 21(9):e3002311. PMID: 37695771.
      Citations: 6     Fields:    Translation:Humans
    30. Plascencia-Villa G, Perry G. Roles of Oxidative Stress in Synaptic Dysfunction and Neuronal Cell Death in Alzheimer's Disease. Antioxidants (Basel). 2023 Aug 17; 12(8). PMID: 37627623.
      Citations:    
    31. Plascencia-Villa G, Perry G. Exploring Molecular Targets for Mitochondrial Therapies in Neurodegenerative Diseases. Int J Mol Sci. 2023 Aug 06; 24(15). PMID: 37569861.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    32. Petrovic N, Essack M, ?ami A, Perry G, Gojobori T, Isenovic ER, Bajic VP. MicroRNA networks linked with BRCA1/2, PTEN, and common genes for Alzheimer's disease and breast cancer share highly enriched pathways that may unravel targets for the AD/BC comorbidity treatment. Comput Biol Chem. 2023 Oct; 106:107925. PMID: 37487248.
      Citations: 1     Fields:    Translation:Humans
    33. Castellani RJ, Perry G. The Teflon hypothesis. Brain Commun. 2023; 5(4):fcad203. PMID: 37492487.
      Citations:    
    34. H?ilund-Carlsen PF, Revheim ME, Costa T, Alavi A, Kepp KP, Sensi SL, Perry G, Robakis NK, Barrio JR, Vissel B. Passive Alzheimer's immunotherapy: A promising or uncertain option? Ageing Res Rev. 2023 09; 90:101996. PMID: 37414156.
      Citations: 6     Fields:    Translation:Humans
    35. Veilleux CC, Garrett EC, Pajic P, Saitou M, Ochieng J, Dagsaan LD, Dominy NJ, Perry GH, Gokcumen O, Melin AD. Human subsistence and signatures of selection on chemosensory genes. Commun Biol. 2023 07 03; 6(1):683. PMID: 37400713.
      Citations:    
    36. H?ilund-Carlsen PF, Revheim ME, Costa T, Kepp KP, Castellani RJ, Perry G, Alavi A, Barrio JR. FDG-PET versus Amyloid-PET Imaging for Diagnosis and Response Evaluation in Alzheimer's Disease: Benefits and Pitfalls. Diagnostics (Basel). 2023 Jul 03; 13(13). PMID: 37443645.
      Citations:    
    37. Lathe R, Schultek NM, Balin BJ, Ehrlich GD, Auber LA, Perry G, Breitschwerdt EB, Corry DB, Doty RL, Rissman RA, Nara PL, Itzhaki R, Eimer WA, Tanzi RE. Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease: Research outline and call for collaboration. Alzheimers Dement. 2023 11; 19(11):5209-5231. PMID: 37283269.
      Citations: 7     Fields:    Translation:Humans
    38. Ebrahimi M, Thompson P, Lauer AK, Sivaprasad S, Perry G. The retina-brain axis and diabetic retinopathy. Eur J Ophthalmol. 2023 Nov; 33(6):2079-2095. PMID: 37259525.
      Citations: 1     Fields:    
    39. Wang W, Zhao F, Lu Y, Siedlak SL, Fujioka H, Feng H, Perry G, Zhu X. Damaged mitochondria coincide with presynaptic vesicle loss and abnormalities in alzheimer's disease brain. Acta Neuropathol Commun. 2023 03 31; 11(1):54. PMID: 37004141.
      Citations: 7     Fields:    Translation:HumansCells
    40. Hampel H, Hu Y, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A. The amyloid-? pathway in Alzheimer's disease: a plain language summary. Neurodegener Dis Manag. 2023 06; 13(3):141-149. PMID: 36994753.
      Citations: 5     Fields:    Translation:Humans
    41. Shobeiri P, Alilou S, Jaberinezhad M, Zare F, Karimi N, Maleki S, Teixeira AL, Perry G, Rezaei N. Circulating long non-coding RNAs as novel diagnostic biomarkers for Alzheimer's disease (AD): A systematic review and meta-analysis. PLoS One. 2023; 18(3):e0281784. PMID: 36947499.
      Citations: 13     Fields:    Translation:Humans
    42. Lea AJ, Clark AG, Dahl AW, Devinsky O, Garcia AR, Golden CD, Kamau J, Kraft TS, Lim YAL, Martins D, Mogoi D, Pajukanta P, Perry G, Pontzer H, Trumble BC, Urlacher SS, Venkataraman VV, Wallace IJ, Gurven M, Lieberman D, Ayroles JF. Evolutionary mismatch and the role of GxE interactions in human disease. ArXiv. 2023 Feb 13. PMID: 36713247.
      Citations:    
    43. Ding P, Gurney M, Perry G, Xu R. Association of COVID-19 with Risk and Progression of Alzheimer's Disease: Non-Overlapping Two-Sample Mendelian Randomization Analysis of 2.6 Million Subjects. J Alzheimers Dis. 2023; 96(4):1711-1720. PMID: 38007657.
      Citations: 1     Fields:    Translation:Humans
    44. Perry G. Slowing the Clock of Life. J Alzheimers Dis. 2023; 95(2):749. PMID: 37574740.
      Citations:    
    45. Atwood CS, Perry G. Playing Russian Roulette with Alzheimer's Disease Patients: Do the Cognitive Benefits of Lecanemab Outweigh the Risk of Edema, Stroke and Encephalitis? J Alzheimers Dis. 2023; 92(3):799-801. PMID: 36847013.
      Citations: 9     Fields:    Translation:Humans
    46. Kepp KP, Sensi SL, Johnsen KB, Barrio JR, H?ilund-Carlsen PF, Neve RL, Alavi A, Herrup K, Perry G, Robakis NK, Vissel B, Espay AJ. The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes. J Alzheimers Dis. 2023; 94(2):497-507. PMID: 37334596.
      Citations: 6     Fields:    Translation:Humans
    47. Avila J, Perry G. Memory, Sleep, and Tau Function. J Alzheimers Dis. 2023; 94(2):491-495. PMID: 37248906.
      Citations:    Fields:    Translation:Humans
    48. Plascencia-Villa G, Perry G. Lessons from antiamyloid-? immunotherapies in Alzheimer's disease. Handb Clin Neurol. 2023; 193:267-292. PMID: 36803816.
      Citations: 10     Fields:    Translation:Humans
    49. Perry G. Alzheimer's Disease: Not Just for the Aged? J Alzheimers Dis. 2023; 91(3):923-924. PMID: 36710685.
      Citations: 2     Fields:    Translation:Humans
    50. Obrenovich M, Singh SK, Li Y, Perry G, Siddiqui B, Haq W, Reddy VP. Natural Product Co-Metabolism and the Microbiota-Gut-Brain Axis in Age-Related Diseases. Life (Basel). 2022 Dec 23; 13(1). PMID: 36675988.
      Citations:    
    51. H?ilund-Carlsen PF, Alavi A, Perry G, Barrio JR. MRI Monitoring of Anti-Alzheimer Therapy Amyloid-Related Imaging Abnormalities: Due Diligence or Overkill? AJNR Am J Neuroradiol. 2023 01; 44(1):E4-E5. PMID: 36574317.
      Citations:    Fields:    Translation:Humans
    52. Ebrahimi M, Sivaprasad S, Thompson P, Perry G. Retinal Neurodegeneration in Euglycemic Hyperinsulinemia, Prediabetes, and Diabetes. Ophthalmic Res. 2023; 66(1):385-397. PMID: 36463857.
      Citations: 3     Fields:    Translation:Humans
    53. Hsieh KL, Plascencia-Villa G, Lin KH, Perry G, Jiang X, Kim Y. Synthesize heterogeneous biological knowledge via representation learning for Alzheimer's disease drug repurposing. iScience. 2023 Jan 20; 26(1):105678. PMID: 36594024.
      Citations:    
    54. Vall?s-Saiz L, Ruiz-Gabarre D, Garc?a-Escudero V, Perry G, Avila J, Hern?ndez F. Mouse and Human Tau Expression in Different Brain Areas. J Alzheimers Dis Rep. 2022; 6(1):677-684. PMID: 36506485.
      Citations:    
    55. Singla RK, De R, Efferth T, Mezzetti B, Sahab Uddin M, Ntie-Kang F, Wang D, Schultz F, Kharat KR, Devkota HP, Battino M, Sur D, Lordan R, Patnaik SS, Tsagkaris C, Sai CS, Tripathi SK, Gaman MA, Ahmed MEO, Gonz?lez-Burgos E, Babiaka SB, Paswan SK, Odimegwu JI, Akram F, Simal-Gandara J, Urquiza MS, Tikhonov A, Mondal H, Singla S, Lonardo SD, Mulholland EJ, Cenanovic M, Maigoro AY, Giampieri F, Lee S, Tzvetkov NT, Louka AM, Verma P, Chopra H, Olea SP, Khan J, Alvarez Suarez JM, Zheng X, Tomczyk M, Sabnani MK, Medina CDV, Khalid GM, Boyina HK, Georgiev MI, Supuran CT, Sobarzo-S?nchez E, Fan TP, Pittala V, Sureda A, Braidy N, Russo GL, Vacca RA, Banach M, Lizard G, Zarrouk A, Hammami S, Orhan IE, Aggarwal BB, Perry G, Miller MJ, Heinrich M, Bishayee A, Kijjoa A, Arkells N, Bredt D, Wink M, Fiebich BL, Kiran G, Yeung AWK, Gupta GK, Santini A, Lucarini M, Durazzo A, El-Demerdash A, Dinkova-Kostova AT, Cifuentes A, Souto EB, Zubair MAM, Badhe P, Echeverr?a J, Horbanczuk JO, Horbanczuk OK, Sheridan H, Sheshe SM, Witkowska AM, Abu-Reidah IM, Riaz M, Ullah H, Oladipupo AR, Lopez V, Sethiya NK, Shrestha BG, Ravanan P, Gupta SC, Alzahrani QE, Dama Sreedhar P, Xiao J, Moosavi MA, Subramani PA, Singh AK, Chettupalli AK, Patra JK, Singh G, Karpinski TM, Al-Rimawi F, Abiri R, Ahmed AF, Barreca D, Vats S, Amrani S, Fimognari C, Mocan A, Hritcu L, Semwal P, Shiblur Rahaman M, Emerald M, Akinrinde AS, Singh A, Joshi A, Joshi T, Khan SY, Balla GOA, Lu A, Pai SR, Ghzaiel I, Acar N, Es-Safi NE, Zengin G, Kureshi AA, Sharma AK, Baral B, Rani N, Jeandet P, Gulati M, Kapoor B, Mohanta YK, Emam-Djomeh Z, Onuku R, Depew JR, Atrooz OM, Goh BH, Andrade JC, Konwar B, Shine VJ, Ferreira JMLD, Ahmad J, Chaturvedi VK, Skalicka-Wozniak K, Sharma R, Gautam RK, Granica S, Parisi S, Kumar R, Atanasov AG, Shen B. The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis. Phytomedicine. 2023 Jan; 108:154520. PMID: 36334386.
      Citations: 15     Fields:    Translation:Humans
    56. Mishra SK, Balendra V, Esposto J, Obaid AA, Maccioni RB, Jha NK, Perry G, Moustafa M, Al-Shehri M, Singh MP, Khan AA, Vamanu E, Singh SK. Therapeutic Antiaging Strategies. Biomedicines. 2022 Oct 08; 10(10). PMID: 36289777.
      Citations:    
    57. Plascencia-Villa G, Perry G. Neuropathologic Changes Provide Insights into Key Mechanisms of Alzheimer Disease and Related Dementia. Am J Pathol. 2022 10; 192(10):1340-1346. PMID: 35931209.
      Citations: 8     Fields:    Translation:HumansCells
    58. Correia SC, Alves MG, Oliveira PF, Casadesus G, LaManna J, Perry G, Moreira PI. Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria. Antioxid Redox Signal. 2022 Oct; 37(10-12):739-757. PMID: 35316086.
      Citations: 3     Fields:    Translation:AnimalsCells
    59. Marciniak S, Bergey CM, Silva AM, Haluszko A, Furmanek M, Veselka B, Velem?nsk? P, Vercellotti G, Wahl J, Zarina G, Longhi C, Kol?r J, Garrido-Pena R, Flores-Fern?ndez R, Herrero-Corral AM, Simalcsik A, M?ller W, Sheridan A, Miliauskiene ?, Jankauskas R, Moiseyev V, K?hler K, Kir?ly ?, Gamarra B, Cheronet O, Szever?nyi V, Kiss V, Szeniczey T, Kiss K, Zoffmann ZK, Ko?s J, Hellebrandt M, Maier RM, Dombor?czki L, Virag C, Novak M, Reich D, Hajdu T, von Cramon-Taubadel N, Pinhasi R, Perry GH. An integrative skeletal and paleogenomic analysis of stature variation suggests relatively reduced health for early European farmers. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2106743119. PMID: 35389750.
      Citations: 13     Fields:    Translation:Humans
    60. Mirzayi P, Shobeiri P, Kalantari A, Perry G, Rezaei N. Optogenetics: implications for Alzheimer's disease research and therapy. Mol Brain. 2022 02 23; 15(1):20. PMID: 35197102.
      Citations: 11     Fields:    Translation:Humans
    61. Sena CM, Sei?a R, Perry G. Editorial: Oxidative Stress Revisited-Major Role in Vascular Diseases, Volume II. Front Physiol. 2021; 12:826129. PMID: 35095578.
      Citations:    
    62. Mandal PK, Perry G. SWADESH: A Comprehensive Platform for Multimodal Data and Analytics for Advanced Research in Alzheimer's Disease and Other Brain Disorders. J Alzheimers Dis. 2022; 85(1):1-5. PMID: 34744083.
      Citations: 1     Fields:    Translation:Humans
    63. Whitehouse P, Gandy S, Saini V, George DR, Larson EB, Alexander GC, Avorn J, Brownlee S, Camp C, Chertkow H, Fugh-Berman A, Howard R, Kesselheim A, Langa KM, Perry G, Richard E, Schneider L. Making the Case for Accelerated Withdrawal of Aducanumab. J Alzheimers Dis. 2022; 87(3):1003-1007. PMID: 35404287.
      Citations: 12     Fields:    Translation:Humans
    64. Xolalpa-Cueva L, Garc?a-Carlos CA, Villase?or-Zepeda R, Orta-Salazar E, D?az-Cintra S, Pe?a-Ortega F, Perry G, Mondrag?n-Rodr?guez S. Hyperphosphorylated Tau Relates to Improved Cognitive Performance and Reduced Hippocampal Excitability in the Young rTg4510 Mouse Model of Tauopathy. J Alzheimers Dis. 2022; 87(2):529-543. PMID: 35342085.
      Citations: 1     Fields:    Translation:HumansAnimals
    65. Ashford JW, Schmitt FA, Bergeron MF, Bayley PJ, Clifford JO, Xu Q, Liu X, Zhou X, Kumar V, Buschke H, Dean M, Finkel SI, Hyer L, Perry G. Now is the Time to Improve Cognitive Screening and Assessment for Clinical and Research Advancement. J Alzheimers Dis. 2022; 87(1):305-315. PMID: 35431257.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    66. Wang Q, Davis PB, Qi X, Chen SG, Gurney ME, Perry G, Doraiswamy PM, Xu R. Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization. Alzheimers Res Ther. 2021 10 20; 13(1):177. PMID: 34670619.
      Citations: 11     Fields:    Translation:AnimalsCells
    67. Ashkarran AA, Hosseini A, Loloee R, Perry G, Lee KB, Lund M, Ejtehadi MR, Mahmoudi M. Conformation- and phosphorylation-dependent electron tunnelling across self-assembled monolayers of tau peptides. J Colloid Interface Sci. 2022 Jan 15; 606(Pt 2):2038-2050. PMID: 34749450.
      Citations: 1     Fields:    Translation:Cells
    68. Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R. Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimers Dement. 2022 06; 18(6):1248-1259. PMID: 34569707.
      Citations: 8     Fields:    Translation:Humans
    69. Mahdiabadi S, Momtazmanesh S, Perry G, Rezaei N. Immune modulations and immunotherapies for Alzheimer's disease: a comprehensive review. Rev Neurosci. 2022 06 27; 33(4):365-381. PMID: 34506700.
      Citations: 5     Fields:    Translation:Humans
    70. Hampel H, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A. The Amyloid-? Pathway in Alzheimer's Disease. Mol Psychiatry. 2021 10; 26(10):5481-5503. PMID: 34456336.
      Citations: 438     Fields:    Translation:Humans
    71. Perry GH. Evolutionary medicine. Elife. 2021 07 22; 10. PMID: 34291730.
      Citations: 5     Fields:    Translation:Humans
    72. Bajic V, Misic N, Stankovic I, Zaric B, Perry G. Alzheimer's and Consciousness: How Much Subjectivity Is Objective? Neurosci Insights. 2021; 16:26331055211033869. PMID: 34350401.
      Citations:    
    73. Marciniak S, Mughal MR, Godfrey LR, Bankoff RJ, Randrianatoandro H, Crowley BE, Bergey CM, Muldoon KM, Randrianasy J, Raharivololona BM, Schuster SC, Malhi RS, Yoder AD, Louis EE, Kistler L, Perry GH. Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, "subfossil" koala lemur Megaladapis edwardsi. Proc Natl Acad Sci U S A. 2021 06 29; 118(26). PMID: 34162703.
      Citations: 7     Fields:    Translation:AnimalsCells
    74. Henry Akintobi T, Sheikhattari P, Shaffer E, Evans CL, Braun KL, Sy AU, Mancera B, Campa A, Miller ST, Sarpong D, Holliday R, Jimenez-Chavez J, Khan S, Hinton C, Sellars-Bates K, Ajewole V, Teufel-Shone NI, McMullin J, Suther S, Kimbro KS, Taylor L, Velez Vega CM, Williams C, Perry G, Zuchner S, Marzan Rodriguez M, Tchounwou PB. Community Engagement Practices at Research Centers in U.S. Minority Institutions: Priority Populations and Innovative Approaches to Advancing Health Disparities Research. Int J Environ Res Public Health. 2021 06 21; 18(12). PMID: 34205781.
      Citations: 6     Fields:    Translation:Humans
    75. Wang C, Shao C, Zhang L, Siedlak SL, Meabon JS, Peskind ER, Lu Y, Wang W, Perry G, Cook DG, Zhu X. Oxidative Stress Signaling in Blast TBI-Induced Tau Phosphorylation. Antioxidants (Basel). 2021 Jun 15; 10(6). PMID: 34203583.
      Citations:    
    76. Everett J, Lermyte F, Brooks J, Tjendana-Tjhin V, Plascencia-Villa G, Hands-Portman I, Donnelly JM, Billimoria K, Perry G, Zhu X, Sadler PJ, O'Connor PB, Collingwood JF, Telling ND. Biogenic metallic elements in the human brain? Sci Adv. 2021 06; 7(24). PMID: 34108207.
      Citations: 28     Fields:    
    77. Talbert PY, Perry G, Ricks-Santi L, Soto de Laurido LE, Shaheen M, Seto T, Kumar D, Quarshie A, Thakar M, Rubio DM. Challenges and Strategies of Successful Mentoring: The Perspective of LEADS Scholars and Mentors from Minority Serving Institutions. Int J Environ Res Public Health. 2021 06 07; 18(11). PMID: 34200278.
      Citations: 5     Fields:    Translation:Humans
    78. Arner AM, Grogan KE, Grabowski M, Reyes-Centeno H, Perry GH. Patterns of recent natural selection on genetic loci associated with sexually differentiated human body size and shape phenotypes. PLoS Genet. 2021 06; 17(6):e1009562. PMID: 34081690.
      Citations: 2     Fields:    Translation:Humans
    79. Pappolla MA, Perry G, Fang X, Zagorski M, Sambamurti K, Poeggeler B. Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease. Neurobiol Dis. 2021 08; 156:105403. PMID: 34087380.
      Citations: 26     Fields:    Translation:HumansAnimals
    80. Hampel H, Nistic? R, Seyfried NT, Levey AI, Modeste E, Lemercier P, Baldacci F, Toschi N, Garaci F, Perry G, Emanuele E, Valenzuela PL, Lucia A, Urbani A, Sancesario GM, Mapstone M, Corbo M, Vergallo A, Lista S. Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence. Ageing Res Rev. 2021 08; 69:101346. PMID: 33915266.
      Citations: 52     Fields:    Translation:Humans
    81. Hernandez M, Perry GH. Scanning the human genome for "signatures" of positive selection: Transformative opportunities and ethical obligations. Evol Anthropol. 2021 Mar; 30(2):113-121. PMID: 33788352.
      Citations: 5     Fields:    Translation:Humans
    82. Sullivan AP, Marciniak S, O'Dea A, Wake TA, Perry GH. Modern, archaeological, and paleontological DNA analysis of a human-harvested marine gastropod (Strombus pugilis) from Caribbean Panama. Mol Ecol Resour. 2021 Jul; 21(5):1517-1528. PMID: 33595921.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    83. Orkin JD, Montague MJ, Tejada-Martinez D, de Manuel M, Del Campo J, Cheves Hernandez S, Di Fiore A, Fontsere C, Hodgson JA, Janiak MC, Kuderna LFK, Lizano E, Martin MP, Niimura Y, Perry GH, Valverde CS, Tang J, Warren WC, de Magalh?es JP, Kawamura S, Marqu?s-Bonet T, Krawetz R, Melin AD. The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS. Proc Natl Acad Sci U S A. 2021 02 16; 118(7). PMID: 33574059.
      Citations: 22     Fields:    Translation:Animals
    84. ?ivkovic L, Bajic V, Cabarkapa-Pirkovic A, Dekanski D, Forbes-Hern?ndez TY, Zlatkovic-?venda M, Perry G, Spremo-Potparevic B. Strawberry (Fragaria ananassa duch.) Alba extract attenuates DNA damage in lymphocytes of patients with Alzheimer's disease. J Food Biochem. 2021 04; 45(4):e13637. PMID: 33547659.
      Citations:    Fields:    Translation:HumansAnimalsCells
    85. Mart?n-Maestro P, Gargini R, Garc?a E, Perry G, Avila J, Garc?a-Escudero V. Corrigendum to "Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease". Oxid Med Cell Longev. 2021; 2021:1643631. PMID: 33510835.
      Citations:    Fields:    
    86. Mart?nez-Maldonado A, Ontiveros-Torres M?, Harrington CR, Montiel-Sosa JF, Prandiz RG, Bocanegra-L?pez P, Sorsby-Vargas AM, Bravo-Mu?oz M, Flor?n-Gardu?o B, Villanueva-Fierro I, Perry G, Garc?s-Ram?rez L, de la Cruz F, Mart?nez-Robles S, Pacheco-Herrero M, Luna-Mu?oz J. Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration. J Alzheimers Dis. 2021; 79(4):1517-1531. PMID: 33459640.
      Citations: 9     Fields:    Translation:HumansCells
    87. Moradian N, Moallemian M, Delavari F, Sedikides C, Camargo CA, Torres PJ, Sorooshian A, Mehdiabadi SP, Nieto JJ, Bordas S, Ahmadieh H, Abdollahi M, Hamblin MR, Sellke FW, Cuzick J, Biykem B, Schreiber M, Eshrati B, Perry G, Montazeri A, Saboury AA, Kelishadi R, Sahebkar A, Moosavi-Movahed AA, Vatandoost H, Gorji-Bandpy M, Mobasher B, Rezaei N. Interdisciplinary Approaches to COVID-19. Adv Exp Med Biol. 2021; 1318:923-936. PMID: 33973220.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    88. Wang L, Liu M, Gao J, Smith AM, Fujioka H, Liang J, Perry G, Wang X. Mitochondrial Fusion Suppresses Tau Pathology-Induced Neurodegeneration and Cognitive Decline. J Alzheimers Dis. 2021; 84(3):1057-1069. PMID: 34602490.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    89. Nunomura A, Perry G. RNA and Oxidative Stress in Alzheimer's Disease: Focus on microRNAs. Oxid Med Cell Longev. 2020; 2020:2638130. PMID: 33312335.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    90. Avila J, Perry G. A Multilevel View of the Development of Alzheimer's Disease. Neuroscience. 2021 03 01; 457:283-293. PMID: 33246061.
      Citations: 25     Fields:    Translation:HumansCells
    91. Forero DA, Lopez-Leon S, Perry G. A brief guide to the science and art of writing manuscripts in biomedicine. J Transl Med. 2020 11 10; 18(1):425. PMID: 33167977.
      Citations: 12     Fields:    
    92. Ashford JW, Gold JE, Huenergardt MA, Katz RBA, Strand SE, Bolanos J, Wheeler CJ, Perry G, Smith CJ, Steinman L, Chen MY, Wang JC, Ashford CB, Roth WT, Cheng JJ, Chao S, Jennings J, Sipple D, Yamamoto V, Kateb B, Earnest DL. MMR Vaccination: A Potential Strategy to Reduce Severity and Mortality of COVID-19 Illness. Am J Med. 2021 02; 134(2):153-155. PMID: 33198951.
      Citations: 19     Fields:    Translation:Humans
    93. Hernandez M, Shenk MK, Perry GH. Factors influencing taxonomic unevenness in scientific research: a mixed-methods case study of non-human primate genomic sequence data generation. R Soc Open Sci. 2020 Sep; 7(9):201206. PMID: 33047065.
      Citations:    
    94. Momtazmanesh S, Perry G, Rezaei N. Toll-like receptors in Alzheimer's disease. J Neuroimmunol. 2020 11 15; 348:577362. PMID: 32858428.
      Citations: 20     Fields:    Translation:HumansAnimals
    95. Kelley AR, Colley M, Dyer S, Bach SBH, Zhu X, Perry G. Ethanol-Fixed, Paraffin-Embedded Tissue Imaging: Implications for Alzheimer's Disease Research. J Am Soc Mass Spectrom. 2020 Dec 02; 31(12):2416-2420. PMID: 32803969.
      Citations: 5     Fields:    Translation:Humans
    96. Nami M, Gadad BS, Chong L, Ghumman U, Misra A, Gadad SS, Kumar D, Perry G, Abraham SJK, Rao KS. The Interrelation of Neurological and Psychological Symptoms of COVID-19: Risks and Remedies. J Clin Med. 2020 Aug 13; 9(8). PMID: 32823540.
      Citations:    
    97. Plascencia-Villa G, Perry G. Status and future directions of clinical trials in Alzheimer's disease. Int Rev Neurobiol. 2020; 154:3-50. PMID: 32739008.
      Citations: 14     Fields:    Translation:Humans
    98. Plascencia-Villa G, Perry G. Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis. Antioxid Redox Signal. 2021 03 10; 34(8):591-610. PMID: 32486897.
      Citations: 57     Fields:    Translation:HumansCells
    99. Gonz?lez-S?nchez M, Bartolome F, Antequera D, Puertas-Mart?n V, Gonz?lez P, G?mez-Grande A, Llamas-Velasco S, Herrero-San Mart?n A, P?rez-Mart?nez D, Villarejo-Galende A, Atienza M, Palomar-Bonet M, Cantero JL, Perry G, Orive G, Iba?ez B, Bueno H, Fuster V, Carro E. Decreased salivary lactoferrin levels are specific to Alzheimer's disease. EBioMedicine. 2020 Jul; 57:102834. PMID: 32586758.
      Citations: 41     Fields:    Translation:Humans
    100. Veurink G, Perry G, Singh SK. Role of antioxidants and a nutrient rich diet in Alzheimer's disease. Open Biol. 2020 06; 10(6):200084. PMID: 32543351.
      Citations: 30     Fields:    Translation:Humans
    101. Messman RD, Contreras-Correa ZE, Paz HA, Perry G, Lemley CO. Vaginal bacterial community composition and concentrations of estradiol at the time of artificial insemination in Brangus heifers. J Anim Sci. 2020 Jun 01; 98(6). PMID: 32515480.
      Citations: 17     Fields:    Translation:AnimalsCells
    102. Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances. Mol Neurodegener. 2020 05 29; 15(1):30. PMID: 32471464.
      Citations: 401     Fields:    Translation:HumansAnimalsCells
    103. Obrenovich M, Jaworski H, Tadimalla T, Mistry A, Sykes L, Perry G, Bonomo RA. The Role of the Microbiota-Gut-Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases. Microorganisms. 2020 May 23; 8(5). PMID: 32456229.
      Citations:    
    104. Obrenovich M, Tabrez S, Siddiqui B, McCloskey B, Perry G. The Microbiota-Gut-Brain Axis-Heart Shunt Part II: Prosaic Foods and the Brain-Heart Connection in Alzheimer Disease. Microorganisms. 2020 Mar 31; 8(4). PMID: 32244373.
      Citations:    
    105. Yeung AWK, Tzvetkov NT, Georgieva MG, Ognyanov IV, Kordos K, J?zwik A, K?hl T, Perry G, Petralia MC, Mazzon E, Atanasov AG. Reactive Oxygen Species and Their Impact in Neurodegenerative Diseases: Literature Landscape Analysis. Antioxid Redox Signal. 2021 02 10; 34(5):402-420. PMID: 32030995.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    106. Mondrag?n-Rodr?guez S, Ordaz B, Orta-Salazar E, D?az-Cintra S, Pe?a-Ortega F, Perry G. Hippocampal Unicellular Recordings and Hippocampal-dependent Innate Behaviors in an Adolescent Mouse Model of Alzheimer's disease. Bio Protoc. 2020 Feb 20; 10(4):e3529. PMID: 33654753.
      Citations:    
    107. Reddy VP, Aryal P, Robinson S, Rafiu R, Obrenovich M, Perry G. Polyphenols in Alzheimer's Disease and in the Gut-Brain Axis. Microorganisms. 2020 Jan 31; 8(2). PMID: 32023969.
      Citations:    
    108. Reyes-Pablo AE, Campa-C?rdoba BB, Luna-Viramontes NI, Ontiveros-Torres M?, Villanueva-Fierro I, Bravo-Mu?oz M, S?enz-Ibarra B, Barbosa O, Guadarrama-Ort?z P, Garc?s-Ram?rez L, de la Cruz F, Harrington CR, Mart?nez-Robles S, Gonz?lez-Ballesteros E, Perry G, Pacheco-Herrero M, Luna-Mu?oz J. National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in M?xico. J Alzheimers Dis. 2020; 76(3):853-862. PMID: 32568191.
      Citations: 4     Fields:    Translation:Humans
    109. Hernandes-Alejandro M, Monta?o S, Harrington CR, Wischik CM, Salas-Casas A, Cortes-Reynosa P, P?rez Salazar E, Cazares-Apatiga J, Apatiga-Perez R, Ontiveros Torres M?, Perry G, Pacheco-Herrero M, Luna-Mu?oz J. Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease. J Alzheimers Dis. 2020; 76(2):553-569. PMID: 32538846.
      Citations: 14     Fields:    Translation:HumansCells
    110. Perry G. Alzheimer's Disease Patients in the Crosshairs of COVID-19. J Alzheimers Dis. 2020; 76(1):1. PMID: 32623403.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    111. Iverson GL, Gardner AJ, Shultz SR, Solomon GS, McCrory P, Zafonte R, Perry G, Hazrati LN, Keene CD, Castellani RJ. Chronic traumatic encephalopathy neuropathology might not be inexorably progressive or unique to repetitive neurotrauma. Brain. 2019 Dec 01; 142(12):3672-3693. PMID: 31670780.
      Citations: 38     Fields:    Translation:Humans
    112. Gao J, Wang L, Gao C, Arakawa H, Perry G, Wang X. TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2020 01 01; 1866(1):165580. PMID: 31678156.
      Citations: 14     Fields:    Translation:AnimalsCells
    113. Aiello P, Consalvi S, Poce G, Raguzzini A, Toti E, Palmery M, Biava M, Bernardi M, Kamal MA, Perry G, Peluso I. Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy. Semin Cancer Biol. 2021 02; 69:150-165. PMID: 31454670.
      Citations: 29     Fields:    Translation:HumansAnimals
    114. Gao J, Wang L, Yan T, Perry G, Wang X. TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration. Mol Cell Neurosci. 2019 10; 100:103396. PMID: 31445085.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    115. Lopez M, Choin J, Sikora M, Siddle K, Harmant C, Costa HA, Silvert M, Mouguiama-Daouda P, Hombert JM, Froment A, Le Bomin S, Perry GH, Barreiro LB, Bustamante CD, Verdu P, Patin E, Quintana-Murci L. Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest. Curr Biol. 2019 09 09; 29(17):2926-2935.e4. PMID: 31402299.
      Citations: 20     Fields:    Translation:HumansCells
    116. Harrison GF, Sanz J, Boulais J, Mina MJ, Grenier JC, Leng Y, Dumaine A, Yotova V, Bergey CM, Nsobya SL, Elledge SJ, Schurr E, Quintana-Murci L, Perry GH, Barreiro LB. Natural selection contributed to immunological differences between hunter-gatherers and agriculturalists. Nat Ecol Evol. 2019 08; 3(8):1253-1264. PMID: 31358949.
      Citations: 20     Fields:    Translation:HumansCells
    117. Luca M, Di Mauro M, Perry G. Neuropsychiatric Disturbances and Diabetes Mellitus: The Role of Oxidative Stress. Oxid Med Cell Longev. 2019; 2019:5698132. PMID: 31354908.
      Citations: 4     Fields:    Translation:Humans
    118. Zavala EI, Rajagopal S, Perry GH, Kruzic I, Ba?ic ?, Parsons TJ, Holland MM. Impact of DNA degradation on massively parallel sequencing-based autosomal STR, iiSNP, and mitochondrial DNA typing systems. Int J Legal Med. 2019 Sep; 133(5):1369-1380. PMID: 31267160.
      Citations: 9     Fields:    Translation:HumansCells
    119. Singh SK, Srivastav S, Castellani RJ, Plascencia-Villa G, Perry G. Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders. Neurotherapeutics. 2019 07; 16(3):666-674. PMID: 31376068.
      Citations: 99     Fields:    Translation:HumansAnimals
    120. Sena CM, Sei?a R, Perry G. Editorial: Oxidative Stress Revisited-Major Role in Vascular Diseases. Front Physiol. 2019; 10:788. PMID: 31293452.
      Citations:    
    121. Jones L, Kumar J, Mistry A, Sankar Chittoor Mana T, Perry G, Reddy VP, Obrenovich M. The Transformative Possibilities of the Microbiota and Mycobiota for Health, Disease, Aging, and Technological Innovation. Biomedicines. 2019 Mar 28; 7(2). PMID: 30925795.
      Citations:    
    122. Samenuk GM, Kelley AR, Perry G, Bach SBH. Rapid method towards proteomic analysis of dried blood spots by MALDI mass spectrometry. Clin Mass Spectrom. 2019 Apr; 12:30-36. PMID: 34841077.
      Citations:    
    123. Ofili EO, Tchounwou PB, Fernandez-Repollet E, Yanagihara R, Akintobi TH, Lee JE, Malouhi M, Garner ST, Hayes TT, Baker AR, Dent AL, Abdelrahim M, Rollins L, Chang SP, Sy A, Hernandez BY, Bullard PL, Noel RJ, Shiramizu B, Hedges JR, Berry MJ, Bond VC, Lima MF, Mokuau N, Kirken RA, Cruz-Correa M, Sarpong DF, Vadgama J, Yates C, Kahn SA, Soliman KF, Perry G, Pezzano M, Luciano CA, Barnett ME, Oyekan A, Kumar D, Norris KC. The Research Centers in Minority Institutions (RCMI) Translational Research Network: Building and Sustaining Capacity for Multi-Site Basic Biomedical, Clinical and Behavioral Research. Ethn Dis. 2019; 29(Suppl 1):135-144. PMID: 30906162.
      Citations: 18     Fields:    Translation:Humans
    124. Castellani RJ, Plascencia-Villa G, Perry G. The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation. Lab Invest. 2019 07; 99(7):958-970. PMID: 30760863.
      Citations: 50     Fields:    Translation:Humans
    125. Espay AJ, Vizcarra JA, Marsili L, Lang AE, Simon DK, Merola A, Josephs KA, Fasano A, Morgante F, Savica R, Greenamyre JT, Cambi F, Yamasaki TR, Tanner CM, Gan-Or Z, Litvan I, Mata IF, Zabetian CP, Brundin P, Fernandez HH, Standaert DG, Kauffman MA, Schwarzschild MA, Sardi SP, Sherer T, Perry G, Leverenz JB. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology. 2019 02 12; 92(7):329-337. PMID: 30745444.
      Citations: 81     Fields:    Translation:Humans
    126. Wang C, Zhao F, Shen K, Wang W, Siedlak SL, Lee HG, Phelix CF, Perry G, Shen L, Tang B, Yan R, Zhu X. The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease. Brain Pathol. 2019 07; 29(4):530-543. PMID: 30515907.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    127. Rodriguez RA, Liang H, Chen LY, Plascencia-Villa G, Perry G. Single-channel permeability and glycerol affinity of human aquaglyceroporin AQP3. Biochim Biophys Acta Biomembr. 2019 04 01; 1861(4):768-775. PMID: 30659792.
      Citations: 10     Fields:    Translation:HumansCells
    128. Castellani RJ, Perry G. Tau Biology, Tauopathy, Traumatic Brain Injury, and Diagnostic Challenges. J Alzheimers Dis. 2019; 67(2):447-467. PMID: 30584140.
      Citations: 38     Fields:    Translation:HumansAnimals
    129. Montero-Odasso M, Perry G. Gait Disorders in Alzheimer's Disease and Other Dementias: There is Something in the Way You Walk. J Alzheimers Dis. 2019; 71(s1):S1-S4. PMID: 31476163.
      Citations: 8     Fields:    Translation:Humans
    130. Hampel H, Vergallo A, Perry G, Lista S. The Alzheimer Precision Medicine Initiative. J Alzheimers Dis. 2019; 68(1):1-24. PMID: 30814352.
      Citations: 32     Fields:    Translation:Humans
    131. Perry G. Preface. Mini Rev Med Chem. 2019; 19(1):2. PMID: 30626312.
      Citations:    Fields:    
    132. Tripathy A, Shade A, Erskine B, Bailey K, Grande A, deLong JJ, Perry G, Castellani RJ. No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study. J Alzheimers Dis. 2019; 67(4):1277-1289. PMID: 30741674.
      Citations: 5     Fields:    Translation:Humans
    133. Castellani RJ, Smith M, Bailey K, Perry G, deJong JL. Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury. J Alzheimers Dis. 2019; 72(3):683-691. PMID: 31609691.
      Citations: 2     Fields:    Translation:Humans
    134. Hampel H, Lista S, Mango D, Nistic? R, Perry G, Avila J, Hernandez F, Geerts H, Vergallo A. Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective. J Alzheimers Dis. 2019; 69(3):615-629. PMID: 31156173.
      Citations: 19     Fields:    Translation:HumansAnimals
    135. Mohammadi A, Maleki-Jamshid A, Sanooghi D, Milan PB, Rahmani A, Sefat F, Shahpasand K, Soleimani M, Bakhtiari M, Belali R, Faghihi F, Joghataei MT, Perry G, Mozafari M. Correction to: Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders. Mol Neurobiol. 2019 Jan; 56(1):319-320. PMID: 29700773.
      Citations:    Fields:    
    136. Flores-Rodr?guez P, Harrington CR, Wischik CM, Ibarra-Bracamontes V, Zarco N, Navarrete A, Mart?nez-Maldonado A, Guadarrama-Ort?z P, Villanueva-Fierro I, Ontiveros-Torres MA, Perry G, Alonso AD, Floran-Gardu?o B, Segovia J, Luna-Mu?oz J. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study. J Alzheimers Dis. 2019; 71(2):631-645. PMID: 31424392.
      Citations: 7     Fields:    Translation:HumansCells
    137. Liu M, Wang L, Gao J, Dong Q, Perry G, Ma X, Wang X. Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice. J Alzheimers Dis. 2019; 69(4):1077-1087. PMID: 31156179.
      Citations: 7     Fields:    Translation:AnimalsCells
    138. Sena CM, Leandro A, Azul L, Sei?a R, Perry G. Vascular Oxidative Stress: Impact and Therapeutic Approaches. Front Physiol. 2018; 9:1668. PMID: 30564132.
      Citations:    
    139. Kelley AR, Bach SBH, Perry G. Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2040-2047. PMID: 30481587.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    140. Bergey CM, Lopez M, Harrison GF, Patin E, Cohen JA, Quintana-Murci L, Barreiro LB, Perry GH. Polygenic adaptation and convergent evolution on growth and cardiac genetic pathways in African and Asian rainforest hunter-gatherers. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):E11256-E11263. PMID: 30413626.
      Citations: 22     Fields:    Translation:Humans
    141. Pinho TS, Correia SC, Perry G, Ambr?sio AF, Moreira PI. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2048-2059. PMID: 30412792.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    142. Peluso I, Palmery M, Yarla NS, Perry G, Kamal MA. From Oxidative Stress to Ageing via Lifestyle, Nutraceuticals, Polypharmacy, and Neuropsychological Factors. Oxid Med Cell Longev. 2018; 2018:6352689. PMID: 30363930.
      Citations: 6     Fields:    Translation:HumansAnimals
    143. Hern?ndez F, Cuadros R, Oll? I, Garc?a C, Ferrer I, Perry G, Avila J. Differences in structure and function between human and murine tau. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2024-2030. PMID: 31189515.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    144. Wang L, Gao J, Liu J, Siedlak SL, Torres S, Fujioka H, Huntley ML, Jiang Y, Ji H, Yan T, Harland M, Termsarasab P, Zeng S, Jiang Z, Liang J, Perry G, Hoppel C, Zhang C, Li H, Wang X. Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles. Cell Metab. 2018 09 04; 28(3):400-414.e8. PMID: 30017354.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    145. Everett J, Collingwood JF, Tjendana-Tjhin V, Brooks J, Lermyte F, Plascencia-Villa G, Hands-Portman I, Dobson J, Perry G, Telling ND. Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects. Nanoscale. 2018 Jul 05; 10(25):11782-11796. PMID: 29688240.
      Citations: 38     Fields:    Translation:Humans
    146. Liang H, Bourdon AK, Chen LY, Phelix CF, Perry G. Gibbs Free-Energy Gradient along the Path of Glucose Transport through Human Glucose Transporter 3. ACS Chem Neurosci. 2018 11 21; 9(11):2815-2823. PMID: 29865792.
      Citations: 6     Fields:    Translation:HumansCells
    147. Mahmoudi M, Pakpour S, Perry G. Drug-Abuse Nanotechnology: Opportunities and Challenges. ACS Chem Neurosci. 2018 10 17; 9(10):2288-2298. PMID: 29851334.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    148. Mondrag?n-Rodr?guez S, Salas-Gallardo A, Gonz?lez-Pereyra P, Mac?as M, Ordaz B, Pe?a-Ortega F, Aguilar-V?zquez A, Orta-Salazar E, D?az-Cintra S, Perry G, Williams S. Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model. J Biol Chem. 2018 06 01; 293(22):8462-8472. PMID: 29632073.
      Citations: 34     Fields:    Translation:AnimalsCells
    149. Paley EL, Perry G. Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration. Nutrients. 2018 Mar 26; 10(4). PMID: 29587458.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    150. Mohammadi A, Maleki-Jamshid A, Sanooghi D, Milan PB, Rahmani A, Sefat F, Shahpasand K, Soleimani M, Bakhtiari M, Belali R, Faghihi F, Joghataei MT, Perry G, Mozafari M. Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders. Mol Neurobiol. 2019 Jan; 56(1):307-318. PMID: 29549645.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    151. Gao J, Wang L, Huntley ML, Perry G, Wang X. Pathomechanisms of TDP-43 in neurodegeneration. J Neurochem. 2018 Feb 27. PMID: 29486049.
      Citations: 94     Fields:    
    152. Hampel H, Vergallo A, Aguilar LF, Benda N, Broich K, Cuello AC, Cummings J, Dubois B, Federoff HJ, Fiandaca M, Genthon R, Haberkamp M, Karran E, Mapstone M, Perry G, Schneider LS, Welikovitch LA, Woodcock J, Baldacci F, Lista S. Precision pharmacology for Alzheimer's disease. Pharmacol Res. 2018 04; 130:331-365. PMID: 29458203.
      Citations: 35     Fields:    Translation:HumansAnimals
    153. Kelley AR, Colley ME, Perry G, Bach SBH. Incubation with Cu(II) and Zn(II) salts enhances MALDI-TOF mass spectra of amyloid-beta and a-synuclein toward in vivo analysis. J Mass Spectrom. 2018 Feb; 53(2):162-171. PMID: 29111606.
      Citations: 1     Fields:    Translation:HumansCells
    154. Jiang S, Nandy P, Wang W, Ma X, Hsia J, Wang C, Wang Z, Niu M, Siedlak SL, Torres S, Fujioka H, Xu Y, Lee HG, Perry G, Liu J, Zhu X. Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex. Mol Neurodegener. 2018 02 01; 13(1):5. PMID: 29391029.
      Citations: 45     Fields:    Translation:AnimalsCells
    155. P?rez-Ibave DC, Rodr?guez-S?nchez IP, Garza-Rodr?guez ML, P?rez-Maya AA, Luna M, Ar?mburo C, Tsin A, Perry G, Mohamed-Noriega K, Mohamed-Noriega J, Cavazos-Adame H, Mohamed-Hamsho J, Barrera-Salda?a HA. Expression of growth hormone gene in the baboon eye. Exp Eye Res. 2018 04; 169:157-169. PMID: 29407222.
      Citations: 3     Fields:    Translation:HumansAnimals
    156. Plascencia-Villa G, Perry G. Iron?ic facts about dementia. J Neurol Neurosurg Psychiatry. 2018 05; 89(5):446-447. PMID: 29353235.
      Citations: 1     Fields:    Translation:Humans
    157. Kelley AR, Perry G, Bach SBH. Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer's Diseased Brains by MALDI-TOF MS with MS/MS. ACS Chem Neurosci. 2018 04 18; 9(4):708-714. PMID: 29301075.
      Citations: 5     Fields:    
    158. Yan T, Wang L, Gao J, Siedlak SL, Huntley ML, Termsarasab P, Perry G, Chen SG, Wang X. Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease. J Alzheimers Dis. 2018; 63(1):157-165. PMID: 29562525.
      Citations: 17     Fields:    Translation:HumansCells
    159. Perry G, Avila J, Moreira PI, Sorensen AA, Tabaton M. Preface. J Alzheimers Dis. 2018; 64(s1):S1. PMID: 29782320.
      Citations:    Fields:    Translation:Humans
    160. Smith MA, Bowen RL, Nguyen RQ, Perry G, Atwood CS, Rimm AA. Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data. J Alzheimers Dis. 2018; 63(4):1269-1277. PMID: 29782310.
      Citations: 4     Fields:    Translation:Humans
    161. Perry G, Avila J, Tabaton M, Zhu X. Birth of JAD: 20 Years Later. J Alzheimers Dis. 2018; 62(3):901. PMID: 29562547.
      Citations:    Fields:    
    162. Perry G. Preface. Mini Rev Med Chem. 2018; 18(1):2. PMID: 29283061.
      Citations:    Fields:    
    163. Reale M, D'Angelo C, Costantini E, Di Nicola M, Yarla NS, Kamal MA, Salvador N, Perry G. Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-? Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology. J Alzheimers Dis. 2018; 62(1):467-476. PMID: 29439355.
      Citations: 12     Fields:    Translation:HumansAnimals
    164. Manyevitch R, Protas M, Scarpiello S, Deliso M, Bass B, Nanajian A, Chang M, Thompson SM, Khoury N, Gonnella R, Trotz M, Moore DB, Harms E, Perry G, Clunes L, Ortiz A, Friedrich JO, Murray IVJ. Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers. Curr Alzheimer Res. 2018; 15(2):164-181. PMID: 28933272.
      Citations: 32     Fields:    Translation:HumansCells
    165. Frank L, Wesson Ashford J, Bayley PJ, Borson S, Buschke H, Cohen D, Cummings JL, Davies P, Dean M, Finkel SI, Hyer L, Perry G, Powers RE, Schmitt F. Genetic Risk of Alzheimer's Disease: Three Wishes Now That the Genie is Out of the Bottle. J Alzheimers Dis. 2018; 66(2):421-423. PMID: 30282369.
      Citations: 3     Fields:    Translation:Humans
    166. Vasquez V, Mitra J, Perry G, Rao KS, Hegde ML. An Inducible Alpha-Synuclein Expressing Neuronal Cell Line Model for Parkinson's Disease1. J Alzheimers Dis. 2018; 66(2):453-460. PMID: 30320583.
      Citations: 8     Fields:    Translation:HumansCells
    167. Iverson GL, Keene CD, Perry G, Castellani RJ. The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features. J Alzheimers Dis. 2018; 61(1):17-28. PMID: 29103039.
      Citations: 24     Fields:    Translation:Humans
    168. Rodriguez RA, Chen LY, Plascencia-Villa G, Perry G. Thermodynamics of Amyloid-? Fibril Elongation: Atomistic Details of the Transition State. ACS Chem Neurosci. 2018 04 18; 9(4):783-789. PMID: 29239603.
      Citations: 15     Fields:    Translation:HumansCells
    169. Zabel M, Nackenoff A, Kirsch WM, Harrison FE, Perry G, Schrag M. Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens. Free Radic Biol Med. 2018 02 01; 115:351-360. PMID: 29253591.
      Citations: 46     Fields:    Translation:Humans
    170. Cornejo A, Aguilar Sandoval F, Caballero L, Machuca L, Mu?oz P, Caballero J, Perry G, Ardiles A, Areche C, Melo F. Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to ? sheet in tau protein linked to Alzheimer's disease. J Enzyme Inhib Med Chem. 2017 Dec; 32(1):945-953. PMID: 28701064.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    171. Henderson LE, Abdelmegeed MA, Yoo SH, Rhee SG, Zhu X, Smith MA, Nguyen RQ, Perry G, Song BJ. Enhanced Phosphorylation of Bax and Its Translocation into Mitochondria in the Brains of Individuals Affiliated with Alzheimer's Disease. Open Neurol J. 2017; 11:48-58. PMID: 29290835.
      Citations:    
    172. Wang W, Yin J, Ma X, Zhao F, Siedlak SL, Wang Z, Torres S, Fujioka H, Xu Y, Perry G, Zhu X. Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model. Hum Mol Genet. 2017 11 01; 26(21):4118-4131. PMID: 28973308.
      Citations: 95     Fields:    Translation:AnimalsCells
    173. Mart?n-Maestro P, Gargini R, Garc?a E, Perry G, Avila J, Garc?a-Escudero V. Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. Oxid Med Cell Longev. 2017; 2017:9302761. PMID: 29201274.
      Citations: 45     Fields:    Translation:HumansCells
    174. Wambo TO, Chen LY, Phelix C, Perry G. Affinity and path of binding xylopyranose unto E.?coli xylose permease. Biochem Biophys Res Commun. 2017 12 09; 494(1-2):202-206. PMID: 29032199.
      Citations: 6     Fields:    Translation:Cells
    175. Barh D, Garc?a-Solano ME, Tiwari S, Bhattacharya A, Jain N, Torres-Moreno D, Ferri B, Silva A, Azevedo V, Ghosh P, Blum K, Conesa-Zamora P, Perry G. BARHL1 Is Downregulated in Alzheimer's Disease and May Regulate Cognitive Functions through ESR1 and Multiple Pathways. Genes (Basel). 2017 Sep 28; 8(10). PMID: 28956815.
      Citations: 6     Fields:    
    176. Peluso I, Yarla NS, Ambra R, Pastore G, Perry G. MAPK signalling pathway in cancers: Olive products as cancer preventive and therapeutic agents. Semin Cancer Biol. 2019 06; 56:185-195. PMID: 28912082.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    177. Nunomura A, Lee HG, Zhu X, Perry G. Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders. Biochem Soc Trans. 2017 Oct 15; 45(5):1053-1066. PMID: 28778984.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    178. Hajipour MJ, Santoso MR, Rezaee F, Aghaverdi H, Mahmoudi M, Perry G. Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology. Trends Biotechnol. 2017 10; 35(10):937-953. PMID: 28666544.
      Citations: 39     Fields:    Translation:HumansAnimals
    179. Rodriguez RA, Chen LY, Plascencia-Villa G, Perry G. Elongation affinity, activation barrier, and stability of A?42 oligomers/fibrils in physiological saline. Biochem Biophys Res Commun. 2017 05 27; 487(2):444-449. PMID: 28427941.
      Citations: 6     Fields:    Translation:Cells
    180. Khalsa DS, Perry G. The Four Pillars of Alzheimer's Prevention. Cerebrum. 2017 Mar-Apr; 2017. PMID: 28698774.
      Citations:    
    181. Doens D, Valiente PA, Mfuh AM, X T Vo A, Tristan A, Carre?o L, Quijada M, Nguyen VT, Perry G, Larionov OV, Lleonart R, Fern?ndez PL. Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease. ACS Chem Neurosci. 2017 06 21; 8(6):1232-1241. PMID: 28150942.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    182. Remington R, Shea TB, Perry G. Nutritional supplements and dementia. Clin Nutr. 2017 04; 36(2):613-614. PMID: 28153502.
      Citations:    Fields:    Translation:Humans
    183. Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. J Alzheimers Dis. 2017; 55(2):749-762. PMID: 27802219.
      Citations: 19     Fields:    Translation:HumansCells
    184. Nunomura A, Zhu X, Perry G. Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration. J Alzheimers Dis. 2017; 55(1):73-75. PMID: 27802241.
      Citations: 4     Fields:    Translation:HumansAnimals
    185. Mondrag?n-Rodr?guez S, Perry G, Pena-Ortega F, Williams S. Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease. Curr Alzheimer Res. 2017; 14(1):40-46. PMID: 27539594.
      Citations: 9     Fields:    Translation:AnimalsCells
    186. Putta S, Yarla NS, Peluso I, Tiwari DK, Reddy GV, Giri PV, Kumar N, Malla R, Rachel V, Bramhachari PV, Reddy D RS, Bade R, Mannarapu M, Barreto GE, Lu DY, Tarasov VV, Chubarev VN, Ribeiro FF, Scotti L, Scotti MT, Kamal MA, Ashraf GM, Aliev G, Perry G, Sarker SD, Rao CV, Bishayee A. Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases. Curr Pharm Des. 2017; 23(41):6321-6346. PMID: 28741457.
      Citations: 12     Fields:    Translation:HumansAnimals
    187. Siedlak SL, Jiang Y, Huntley ML, Wang L, Gao J, Xie F, Liu J, Su B, Perry G, Wang X. TMEM230 Accumulation in Granulovacuolar Degeneration Bodies and Dystrophic Neurites of Alzheimer's Disease. J Alzheimers Dis. 2017; 58(4):1027-1033. PMID: 28527219.
      Citations: 6     Fields:    Translation:HumansCells
    188. Castellani RJ, Perry G. Dementia Pugilistica Revisited. J Alzheimers Dis. 2017; 60(4):1209-1221. PMID: 29036831.
      Citations: 12     Fields:    Translation:HumansAnimals
    189. Forero DA, Prada CF, Perry G. Functional and Genomic Features of Human Genes Mutated in Neuropsychiatric Disorders. Open Neurol J. 2016; 10:143-148. PMID: 27990183.
      Citations:    
    190. Castellani RJ, Mojica G, Perry G. The Role of the Iron Stain in Assessing Intracranial Hemorrhage. Open Neurol J. 2016; 10:136-142. PMID: 27857815.
      Citations:    
    191. Perry G. Promise from the Sea. Mar Drugs. 2016 Oct 09; 14(10). PMID: 27735831.
      Citations: 1     Fields:    Translation:HumansAnimals
    192. Kelley AR, Perry G, Bethea C, Castellani RJ, Bach SB. Molecular Mapping Alzheimer's Disease: MALDI Imaging of Formalin-fixed, Paraffin-embedded Human Hippocampal Tissue. Open Neurol J. 2016; 10:88-98. PMID: 27843502.
      Citations:    
    193. Aryan N, Betts-Obregon BS, Perry G, Tsin AT. Oxidative Stress Induces Senescence in Cultured RPE Cells. Open Neurol J. 2016; 10:83-7. PMID: 27651846.
      Citations:    
    194. Correia SC, Perry G, Moreira PI. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks. Biochim Biophys Acta. 2016 10; 1862(10):1909-17. PMID: 27460705.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    195. Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, Perry G, Odetti P, Arancio O, Tamagno E, Tabaton M. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. 2016 10; 15(5):914-23. PMID: 27406053.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    196. Herrera L, Stephens DE, D'Avila A, George KG, Arman H, Zhang Y, Perry G, Lleonart R, Larionov OV, Fern?ndez PL. Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles. Org Biomol Chem. 2016 Aug 07; 14(29):7053-60. PMID: 27376396.
      Citations: 6     Fields:    Translation:AnimalsCells
    197. Pistollato F, Ohayon EL, Lam A, Langley GR, Novak TJ, Pamies D, Perry G, Trushina E, Williams RS, Roher AE, Hartung T, Harnad S, Barnard N, Morris MC, Lai MC, Merkley R, Chandrasekera PC. Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities. Oncotarget. 2016 Jun 28; 7(26):38999-39016. PMID: 27229915.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    198. Hofer T, Perry G. Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis? J Trace Elem Med Biol. 2016 Dec; 38:1-9. PMID: 27329321.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    199. Plascencia-Villa G, Ponce A, Collingwood JF, Arellano-Jim?nez MJ, Zhu X, Rogers JT, Betancourt I, Jos?-Yacam?n M, Perry G. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Sci Rep. 2016 04 28; 6:24873. PMID: 27121137.
      Citations: 53     Fields:    Translation:Humans
    200. Forero DA, Gonz?lez-Giraldo Y, L?pez-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Meta-analysis of Telomere Length in Alzheimer's Disease. J Gerontol A Biol Sci Med Sci. 2016 08; 71(8):1069-73. PMID: 27091133.
      Citations: 88     Fields:    Translation:HumansCells
    201. Ontiveros-Torres M?, Labra-Barrios ML, D?az-Cintra S, Aguilar-V?zquez AR, Moreno-Campuzano S, Flores-Rodr?guez P, Luna-Herrera C, Mena R, Perry G, Flor?n-Gardu?o B, Luna-Mu?oz J, Luna-Arias JP. Fibrillar Amyloid-? Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3?Tg-AD Transgenic Mouse. J Alzheimers Dis. 2016 03 22; 52(1):243-69. PMID: 27031470.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    202. Wang C, Zhang F, Jiang S, Siedlak SL, Shen L, Perry G, Wang X, Tang B, Zhu X. Estrogen receptor-a is localized to neurofibrillary tangles in Alzheimer's disease. Sci Rep. 2016 Feb 03; 6:20352. PMID: 26837465.
      Citations: 28     Fields:    Translation:HumansCells
    203. Yu L, Rodriguez RA, Chen LL, Chen LY, Perry G, McHardy SF, Yeh CK. 1,3-propanediol binds deep inside the channel to inhibit water permeation through aquaporins. Protein Sci. 2016 Feb; 25(2):433-41. PMID: 26481430.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    204. Calder?n-Garcidue?as L, Reynoso-Robles R, Vargas-Mart?nez J, G?mez-Maqueo-Chew A, P?rez-Guill? B, Mukherjee PS, Torres-Jard?n R, Perry G, G?nzalez-Maciel A. Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease. Environ Res. 2016 Apr; 146:404-17. PMID: 26829765.
      Citations: 62     Fields:    Translation:HumansAnimalsPHPublic Health
    205. Forero DA, Gonz?lez-Giraldo Y, L?pez-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Telomere length in Parkinson's disease: A meta-analysis. Exp Gerontol. 2016 Mar; 75:53-5. PMID: 26772888.
      Citations: 25     Fields:    Translation:HumansCells
    206. Kelley AR, Perry G, Castellani RJ, Bach SB. Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer's Brains. ACS Chem Neurosci. 2016 Mar 16; 7(3):261-8. PMID: 26720297.
      Citations: 7     Fields:    Translation:Humans
    207. Forero DA, Wonkam A, Wang W, Laissue P, L?pez-Correa C, Fern?ndez-L?pez JC, Mugasimangalam R, Perry G. Current needs for human and medical genomics research infrastructure in low and middle income countries. J Med Genet. 2016 07; 53(7):438-40. PMID: 26740506.
      Citations: 8     Fields:    Translation:Humans
    208. Itzhaki RF, Lathe R, Balin BJ, Ball MJ, Bearer EL, Braak H, Bullido MJ, Carter C, Clerici M, Cosby SL, Del Tredici K, Field H, Fulop T, Grassi C, Griffin WS, Haas J, Hudson AP, Kamer AR, Kell DB, Licastro F, Letenneur L, L?vheim H, Mancuso R, Miklossy J, Otth C, Palamara AT, Perry G, Preston C, Pretorius E, Strandberg T, Tabet N, Taylor-Robinson SD, Whittum-Hudson JA. Microbes and Alzheimer's Disease. J Alzheimers Dis. 2016; 51(4):979-84. PMID: 26967229.
      Citations: 239     Fields:    Translation:HumansAnimals
    209. Mart?n-Maestro P, Gargini R, Perry G, Avila J, Garc?a-Escudero V. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. Hum Mol Genet. 2016 Feb 15; 25(4):792-806. PMID: 26721933.
      Citations: 85     Fields:    Translation:HumansCells
    210. Singh SK, Srivastav S, Yadav AK, Srikrishna S, Perry G. Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting A? by Using Several Synthetic and Herbal Compounds. Oxid Med Cell Longev. 2016; 2016:7361613. PMID: 27034741.
      Citations: 61     Fields:    Translation:HumansAnimals
    211. Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016 09; 21(9):1263-71. PMID: 26619807.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    212. Jiang Z, Wang W, Perry G, Zhu X, Wang X. Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis. Transl Neurodegener. 2015; 4:14. PMID: 26225210.
      Citations: 23     Fields:    
    213. Calder?n-Garcidue?as L, Franco-Lira M, D'Angiulli A, Rodr?guez-D?az J, Blaurock-Busch E, Busch Y, Chao CK, Thompson C, Mukherjee PS, Torres-Jard?n R, Perry G. Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease. Environ Res. 2015 Jul; 140:579-92. PMID: 26037109.
      Citations: 39     Fields:    Translation:Humans
    214. Castellani RJ, Perry G, Iverson GL. Chronic effects of mild neurotrauma: putting the cart before the horse? J Neuropathol Exp Neurol. 2015 Jun; 74(6):493-9. PMID: 25933385.
      Citations: 15     Fields:    Translation:Humans
    215. Zhang F, Wang W, Siedlak SL, Liu Y, Liu J, Jiang K, Perry G, Zhu X, Wang X. Miro1 deficiency in amyotrophic lateral sclerosis. Front Aging Neurosci. 2015; 7:100. PMID: 26074815.
      Citations:    
    216. Zhang F, Su B, Wang C, Siedlak SL, Mondragon-Rodriguez S, Lee HG, Wang X, Perry G, Zhu X. Posttranslational modifications of a-tubulin in alzheimer disease. Transl Neurodegener. 2015; 4:9. PMID: 26029362.
      Citations: 55     Fields:    
    217. Gerenu G, Liu K, Chojnacki JE, Saathoff JM, Mart?nez-Mart?n P, Perry G, Zhu X, Lee HG, Zhang S. Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model. ACS Chem Neurosci. 2015 Aug 19; 6(8):1393-1399. PMID: 25893520.
      Citations: 20     Fields:    Translation:AnimalsCells
    218. Avila J, Perry G, Strange BA, Hernandez F. Alternative neural circuitry that might be impaired in the development of Alzheimer disease. Front Neurosci. 2015; 9:145. PMID: 25954151.
      Citations:    
    219. Rodriguez AR, Plascencia-Villa G, Witt CM, Yu JJ, Jos?-Yacam?n M, Chambers JP, Perry G, Guentzel MN, Arulanandam BP. Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells. Cell Immunol. 2015 Jun; 295(2):83-91. PMID: 25863744.
      Citations: 5     Fields:    Translation:AnimalsCells
    220. Pelcovits A, Marriotti R, Heath J, Perry G, Castellani RJ. Simultaneous onset of Alzheimer's disease in a husband and wife in their mid-fifties: what do we really know about environmental factors? Open Neurol J. 2015; 9:1-3. PMID: 25932054.
      Citations:    
    221. Carvalho C, Correia SC, Perry G, Castellani RJ, Moreira PI. Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview. J Neural Transm (Vienna). 2016 Feb; 123(2):107-11. PMID: 25608860.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    222. Petersen RB, Lissemore FM, Appleby B, Aggarwal N, Boyatzis R, Casadesus G, Cummings J, Jack A, Perry G, Safar J, Sajatovic M, Surewicz WK, Wang Y, Whitehouse P, Lerner A. From Neurodegeneration to Brain Health: An Integrated Approach. J Alzheimers Dis. 2015; 46(1):271-83. PMID: 25720413.
      Citations: 1     Fields:    Translation:HumansAnimals
    223. Spremo-Potparevic B, Bajic V, Perry G, Zivkovic L. Alterations of the X Chromosome in Lymphocytes of Alzheimer's Disease Patients. Curr Alzheimer Res. 2015; 12(10):990-6. PMID: 26502819.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    224. Bowen RL, Perry G, Xiong C, Smith MA, Atwood CS. A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks. J Alzheimers Dis. 2015; 44(2):549-60. PMID: 25310993.
      Citations: 25     Fields:    Translation:Humans
    225. Luna-Mu?oz J, Perry G, Guevara J. Ra?l Mena: 1953-2014. J Alzheimers Dis. 2015; 45(2):325-7. PMID: 25757649.
      Citations:    Fields:    Translation:Humans
    226. Perry G. Two hundred treasured issues! J Alzheimers Dis. 2015; 44(3):725. PMID: 25663057.
      Citations:    Fields:    Translation:Humans
    227. Forero DA, V?lez-van-Meerbeke A, Deshpande SN, Nicolini H, Perry G. Neuropsychiatric genetics in developing countries: Current challenges. World J Psychiatry. 2014 Dec 22; 4(4):69-71. PMID: 25540721.
      Citations:    
    228. Fornicola W, Pelcovits A, Li BX, Heath J, Perry G, Castellani RJ. Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-? and Phosphorylated Tau. Open Neurol J. 2014; 8:22-6. PMID: 25628768.
      Citations:    
    229. Habibi L, Perry G, Mahmoudi M. Global warming and neurodegenerative disorders: speculations on their linkage. Bioimpacts. 2014; 4(4):167-70. PMID: 25671171.
      Citations:    
    230. Xia J, Rocke DM, Perry G, Ray M. Differential network analyses of Alzheimer's disease identify early events in Alzheimer's disease pathology. Int J Alzheimers Dis. 2014; 2014:721453. PMID: 25147748.
      Citations:    
    231. Rodrigues R, Petersen RB, Perry G. Parallels between major depressive disorder and Alzheimer's disease: role of oxidative stress and genetic vulnerability. Cell Mol Neurobiol. 2014 Oct; 34(7):925-49. PMID: 24927694.
      Citations: 31     Fields:    Translation:Humans
    232. Blair JA, Siedlak SL, Wolfram JA, Nunomura A, Castellani RJ, Ferreira ST, Klein WL, Wang Y, Casadesus G, Smith MA, Perry G, Zhu X, Lee HG. Accumulation of intraneuronal amyloid-? is common in normal brain. Curr Alzheimer Res. 2014 May; 11(4):317-24. PMID: 24597504.
      Citations: 8     Fields:    Translation:Humans
    233. Bonda DJ, Wang X, Lee HG, Smith MA, Perry G, Zhu X. Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass. Neurosci Bull. 2014 Apr; 30(2):243-52. PMID: 24733654.
      Citations: 50     Fields:    Translation:HumansCells
    234. Johnston JM, Hu WT, Fardo DW, Greco SJ, Perry G, Montine TJ, Trojanowski JQ, Shaw LM, Ashford JW, Tezapsidis N. Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential. Curr Alzheimer Res. 2014 Feb; 11(2):165-74. PMID: 24359504.
      Citations: 28     Fields:    Translation:Humans
    235. Mondrag?n-Rodr?guez S, Perry G, Luna-Mu?oz J, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome. Neuropathol Appl Neurobiol. 2014 Feb; 40(2):121-35. PMID: 24033439.
      Citations: 138     Fields:    Translation:HumansCells
    236. Perry G, Castellani R. Plaques and tangles: birthmarks of the aging soul. Preface. Biochem Pharmacol. 2014 Apr 15; 88(4):423-5. PMID: 24486570.
      Citations:    Fields:    Translation:HumansCells
    237. Castellani RJ, Perry G. The complexities of the pathology-pathogenesis relationship in Alzheimer disease. Biochem Pharmacol. 2014 Apr 15; 88(4):671-6. PMID: 24447936.
      Citations: 36     Fields:    Translation:Humans
    238. Rosen AC, Ashford JW, Perry G. Ethics review as a catalyst for progress. J Alzheimers Dis. 2014; 40(2):233-5. PMID: 24583402.
      Citations:    Fields:    Translation:HumansAnimals
    239. Fawver JN, Ghiwot Y, Koola C, Carrera W, Rodriguez-Rivera J, Hernandez C, Dineley KT, Kong Y, Li J, Jhamandas J, Perry G, Murray IV. Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease. Curr Alzheimer Res. 2014; 11(10):928-40. PMID: 25387341.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    240. Brinkley WR, Perry G. Lester (Skip) Binder (1949-2013): in the beginning was tau. J Alzheimers Dis. 2014; 40 Suppl 1:S5. PMID: 24867914.
      Citations:    Fields:    Translation:HumansAnimals
    241. Hoffmann C, Zimmermann A, Hinney A, Volckmar AL, Jarrett HW, Fromme T, Klingenspor M. A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes. PLoS One. 2013; 8(12):e83426. PMID: 24391766.
      Citations: 12     Fields:    Translation:AnimalsCells
    242. Bharadwaj PR, Bates KA, Porter T, Teimouri E, Perry G, Steele JW, Gandy S, Groth D, Martins RN, Verdile G. Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases. Transl Psychiatry. 2013 Dec 03; 3:e332. PMID: 24301650.
      Citations: 31     Fields:    Translation:HumansAnimals
    243. Jarero-Basulto JJ, Luna-Mu?oz J, Mena R, Kristofikova Z, Ripova D, Perry G, Binder LI, Garcia-Sierra F. Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease. J Neuropathol Exp Neurol. 2013 Dec; 72(12):1145-61. PMID: 24226268.
      Citations: 25     Fields:    Translation:HumansCells
    244. Fujioka H, Phelix CF, Friedland RP, Zhu X, Perry EA, Castellani RJ, Perry G. Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease. J Health Care Poor Underserved. 2013 Nov; 24(4 Suppl):70-8. PMID: 24241262.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    245. Wang X, Wang W, Li L, Perry G, Lee HG, Zhu X. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochim Biophys Acta. 2014 Aug; 1842(8):1240-7. PMID: 24189435.
      Citations: 534     Fields:    Translation:HumansAnimalsCells
    246. Paley EL, Perry G, Sokolova O. Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency. Curr Alzheimer Res. 2013 Nov; 10(9):987-1004. PMID: 24117115.
      Citations: 8     Fields:    Translation:AnimalsCells
    247. Williams WM, Torres S, Siedlak SL, Castellani RJ, Perry G, Smith MA, Zhu X. Antimicrobial peptide ?-defensin-1 expression is upregulated in Alzheimer's brain. J Neuroinflammation. 2013 Oct 18; 10:127. PMID: 24139179.
      Citations: 26     Fields:    Translation:HumansCells
    248. Correia SC, Perry G, Castellani R, Moreira PI. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease? J Neurochem. 2013 Oct; 127(1):4-6. PMID: 24074055.
      Citations: 1     Fields:    Translation:HumansAnimals
    249. Li W, Murthy AK, Lanka GK, Chetty SL, Yu JJ, Chambers JP, Zhong G, Forsthuber TG, Guentzel MN, Arulanandam BP. A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice. Vaccine. 2013 Nov 19; 31(48):5722-8. PMID: 24096029.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    250. Bonda DJ, Stone JG, Torres SL, Siedlak SL, Perry G, Kryscio R, Jicha G, Casadesus G, Smith MA, Zhu X, Lee HG. Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance. J Neurochem. 2014 Jan; 128(1):162-72. PMID: 23895348.
      Citations: 70     Fields:    Translation:HumansCells
    251. Schrag M, Mueller C, Zabel M, Crofton A, Kirsch WM, Ghribi O, Squitti R, Perry G. Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis. Neurobiol Dis. 2013 Nov; 59:100-10. PMID: 23867235.
      Citations: 122     Fields:    Translation:HumansAnimalsCells
    252. Mondrag?n-Rodr?guez S, Perry G, Zhu X, Moreira PI, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease. Oxid Med Cell Longev. 2013; 2013:940603. PMID: 23936615.
      Citations: 68     Fields:    Translation:HumansCells
    253. Garc?a-Escudero V, Mart?n-Maestro P, Perry G, Avila J. Deconstructing mitochondrial dysfunction in Alzheimer disease. Oxid Med Cell Longev. 2013; 2013:162152. PMID: 23840916.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    254. Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free Radic Res. 2013 Jul; 47(6-7):507-10. PMID: 23566300.
      Citations: 9     Fields:    Translation:Animals
    255. Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Curr Alzheimer Res. 2013 May 01; 10(4):406-19. PMID: 23061885.
      Citations: 45     Fields:    Translation:AnimalsCells
    256. Perry G. Reply: comments on "The effects of vaccination on serum hormone concentrations and conception rates in synchronized naive beef heifers". Theriogenology. 2013 Jul 01; 80(1):71. PMID: 23628363.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    257. Haldar S, Beveridge 'J, Wong J, Singh A, Galimberti D, Borroni B, Zhu X, Blevins J, Greenlee J, Perry G, Mukhopadhyay CK, Schmotzer C, Singh N. A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD. Antioxid Redox Signal. 2013 Nov 10; 19(14):1662-75. PMID: 23379482.
      Citations: 10     Fields:    Translation:Humans
    258. Dur?n-Gonz?lez J, Michi ED, Elorza B, Perez-C?rdova MG, Pacheco-Otalora LF, Touhami A, Paulson P, Perry G, Murray IV, Colom LV. Amyloid ? peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system. Neurobiol Aging. 2013 Aug; 34(8):2071-6. PMID: 23473707.
      Citations: 13     Fields:    Translation:Animals
    259. Zivkovic L, Spremo-Potparevic B, Siedlak SL, Perry G, Pleca?-Solarovic B, Milicevic Z, Bajic VP. DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division. Neurodegener Dis. 2013; 12(3):156-63. PMID: 23406622.
      Citations: 6     Fields:    Translation:HumansCells
    260. Perry G, Zhu X, Smith MA, Sorensen A, Avila J. Preface. Alzheimer's disease: advances for a new century. J Alzheimers Dis. 2013; 33 Suppl 1:S1. PMID: 23397602.
      Citations: 2     Fields:    Translation:Humans
    261. Colom LV, Perry G, Kuljis RO. Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease. Curr Alzheimer Res. 2013 Jan; 10(1):108-16. PMID: 23368433.
      Citations: 4     Fields:    Translation:Humans
    262. Perry G. The largest unmet market: chronic diseases of aging. Mini Rev Med Chem. 2013 Jan; 13(1):1. PMID: 23447815.
      Citations:    Fields:    Translation:Humans
    263. Zhu X, Perry G, Smith MA, Wang X. Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis. 2013; 33 Suppl 1:S253-62. PMID: 22531428.
      Citations: 120     Fields:    Translation:HumansAnimalsCells
    264. Hou L, Lee HG, Han F, Tedesco JM, Perry G, Smith MA, Zagorski MG. Modification of amyloid-?1-42 fibril structure by methionine-35 oxidation. J Alzheimers Dis. 2013; 37(1):9-18. PMID: 23719512.
      Citations: 13     Fields:    Translation:HumansCells
    265. Coskuner O, Wise-Scira O, Perry G, Kitahara T. The structures of the E22? mutant-type amyloid-? alloforms and the impact of E22? mutation on the structures of the wild-type amyloid-? alloforms. ACS Chem Neurosci. 2013 Feb 20; 4(2):310-20. PMID: 23421682.
      Citations: 14     Fields:    Translation:HumansCells
    266. Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxid Redox Signal. 2013 Jun 20; 18(18):2444-57. PMID: 23216311.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    267. Greco SJ, Hamzelou A, Johnston JM, Richardson S, Smith MA, Perry G, Ashford JW, Tezapsidis N. Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest. Curr Alzheimer Res. 2012 Dec; 9(10):1168-73. PMID: 22950840.
      Citations:    Fields:    Translation:Humans
    268. Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Pl?cido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. IUBMB Life. 2012 Dec; 64(12):951-7. PMID: 23129399.
      Citations: 30     Fields:    Translation:HumansCells
    269. Castellani RJ, Perry G. Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress. Arch Med Res. 2012 Nov; 43(8):694-8. PMID: 23085451.
      Citations: 38     Fields:    Translation:HumansCells
    270. Miklossy J, Donta S, Mueller K, Nolte O, Perry G. Chronic or late lyme neuroborreliosis: present and future. Open Neurol J. 2012; 6:78. PMID: 23091567.
      Citations:    
    271. Morelli L, Perry G, Tagliavini F. The contribution of the amyloid hypothesis to the understanding of Alzheimer's disease: a critical overview. Int J Alzheimers Dis. 2012; 2012:709613. PMID: 22970405.
      Citations:    
    272. Piccini A, Borghi R, Guglielmotto M, Tamagno E, Cirmena G, Garuti A, Pollero V, Cammarata S, Fornaro M, Messa M, Colombo L, Salmona M, Perry G, Tabaton M. ?-amyloid 1-42 induces physiological transcriptional regulation of BACE1. J Neurochem. 2012 Sep; 122(5):1023-31. PMID: 22708832.
      Citations: 12     Fields:    Translation:HumansCells
    273. Mondrag?n-Rodr?guez S, Perry G, Zhu X, Moreira PI, Williams S. Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target? Int J Alzheimers Dis. 2012; 2012:276803. PMID: 22779025.
      Citations:    
    274. Wise-Scira O, Xu L, Perry G, Coskuner O. Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-?(1-40) and zinc(II)-bound amyloid-?(1-42) with dynamics. J Biol Inorg Chem. 2012 Aug; 17(6):927-38. PMID: 22674434.
      Citations: 16     Fields:    Translation:Cells
    275. Nunomura A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotox Res. 2012 Oct; 22(3):231-48. PMID: 22669748.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    276. Rodrigues R, Smith MA, Wang X, Perry G, Lee HG, Zhu X, Petersen RB. Molecular neuropathogenesis of Alzheimer's disease: an interaction model stressing the central role of oxidative stress. Future Neurol. 2012 May; 7(3):287-305. PMID: 23086377.
      Citations:    
    277. Liu G, Men P, Zhu X, Perry G. Iron chelation and nanoparticle target delivery in the development of new multifunctional disease-modifying drugs for Alzheimer's disease. Ther Deliv. 2012 May; 3(5):571-4. PMID: 22834400.
      Citations: 1     Fields:    Translation:HumansAnimals
    278. Williams WM, Castellani RJ, Weinberg A, Perry G, Smith MA. Do ?-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration? ScientificWorldJournal. 2012; 2012:905785. PMID: 22606066.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    279. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, B?nhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, B?chet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahov? M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronj? MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, D?az-Araya G, D?az-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farr? JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, F?s?s L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490.
      Citations: 1819     Fields:    Translation:HumansAnimals
    280. Castellani RJ, Moreira PI, Perry G, Zhu X. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors. 2012 Mar-Apr; 38(2):133-8. PMID: 22447715.
      Citations: 31     Fields:    Translation:HumansAnimals
    281. Mondrag?n-Rodr?guez S, Perry G, Zhu X, Boehm J. Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy. Int J Alzheimers Dis. 2012; 2012:630182. PMID: 22482074.
      Citations:    
    282. Nunomura A, Tamaoki T, Motohashi N, Nakamura M, McKeel DW, Tabaton M, Lee HG, Smith MA, Perry G, Zhu X. The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. J Neuropathol Exp Neurol. 2012 Mar; 71(3):233-41. PMID: 22318126.
      Citations: 54     Fields:    Translation:HumansCells
    283. Perry GH, Xue Y, Smith RS, Meyer WK, Caliskan M, Yanez-Cuna O, Lee AS, Guti?rrez-Arcelus M, Ober C, Hollox EJ, Tyler-Smith C, Lee C. Evolutionary genetics of the human Rh blood group system. Hum Genet. 2012 Jul; 131(7):1205-16. PMID: 22367406.
      Citations: 7     Fields:    Translation:HumansCells
    284. Reed-Cossairt A, Zhu X, Lee HG, Reed C, Perry G, Petersen RB. Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome. Curr Gerontol Geriatr Res. 2012; 2012:929734. PMID: 22400025.
      Citations:    
    285. Bonda DJ, Liu G, Men P, Perry G, Smith MA, Zhu X. Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming! CNS Neurol Disord Drug Targets. 2012 Feb; 11(1):81-5. PMID: 22229318.
      Citations: 11     Fields:    Translation:HumansAnimals
    286. Santos RX, Correia SC, Zhu X, Lee HG, Petersen RB, Nunomura A, Smith MA, Perry G, Moreira PI. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease. Free Radic Res. 2012 Apr; 46(4):565-76. PMID: 22149654.
      Citations: 19     Fields:    Translation:HumansCells
    287. Zhu X, Castellani RJ, Ziats NP, Petersen RB, Gon Lee H, Perry G. Mark A. Smith: neurocytochemistry innovator. J Neurochem. 2012 Mar; 120(6):1139-40. PMID: 22268813.
      Citations:    Fields:    Translation:HumansCells
    288. Wang X, Yan MH, Fujioka H, Liu J, Wilson-Delfosse A, Chen SG, Perry G, Casadesus G, Zhu X. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum Mol Genet. 2012 May 01; 21(9):1931-44. PMID: 22228096.
      Citations: 236     Fields:    Translation:HumansAnimalsCells
    289. Perry G, Phelix CF, Nunomura A, Colom LV, Castellani RJ, Petersen RB, Lee HG, Zhu X. Untangling the vascular web from Alzheimer disease and oxidative stress. Can J Neurol Sci. 2012 Jan; 39(1):4. PMID: 22384486.
      Citations:    Fields:    Translation:Humans
    290. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases. Adv Exp Med Biol. 2012; 724:205-21. PMID: 22411245.
      Citations: 27     Fields:    Translation:HumansCells
    291. Perry G. Editorial: a new era for medicinal chemistry. Mini Rev Med Chem. 2012 Jan; 12(1):1. PMID: 22360667.
      Citations:    Fields:    
    292. Calder?n-Garcidue?as L, Kavanaugh M, Block M, D'Angiulli A, Delgado-Ch?vez R, Torres-Jard?n R, Gonz?lez-Maciel A, Reynoso-Robles R, Osnaya N, Villarreal-Calderon R, Guo R, Hua Z, Zhu H, Perry G, Diaz P. Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults. J Alzheimers Dis. 2012; 28(1):93-107. PMID: 21955814.
      Citations: 116     Fields:    Translation:HumansCellsPHPublic Health
    293. Perry GH, Melsted P, Marioni JC, Wang Y, Bainer R, Pickrell JK, Michelini K, Zehr S, Yoder AD, Stephens M, Pritchard JK, Gilad Y. Comparative RNA sequencing reveals substantial genetic variation in endangered primates. Genome Res. 2012 Apr; 22(4):602-10. PMID: 22207615.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    294. Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G, Zhu X. Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. J Neurochem. 2012 Feb; 120(3):419-29. PMID: 22077634.
      Citations: 235     Fields:    Translation:HumansCells
    295. Perry GH, Reeves D, Melsted P, Ratan A, Miller W, Michelini K, Louis EE, Pritchard JK, Mason CE, Gilad Y. A genome sequence resource for the aye-aye (Daubentonia madagascariensis), a nocturnal lemur from Madagascar. Genome Biol Evol. 2012; 4(2):126-35. PMID: 22155688.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    296. Colom LV, Castaneda MT, Hernandez S, Perry G, Jaime S, Touhami A. Intrahippocampal amyloid-? (1-40) injections injure medial septal neurons in rats. Curr Alzheimer Res. 2011 Dec; 8(8):832-40. PMID: 22044024.
      Citations: 12     Fields:    Translation:Animals
    297. Wise-Scira O, Xu L, Kitahara T, Perry G, Coskuner O. Amyloid-? peptide structure in aqueous solution varies with fragment size. J Chem Phys. 2011 Nov 28; 135(20):205101. PMID: 22128957.
      Citations: 21     Fields:    Translation:HumansCells
    298. Kudo W, Lee HP, Zou WQ, Wang X, Perry G, Zhu X, Smith MA, Petersen RB, Lee HG. Cellular prion protein is essential for oligomeric amyloid-?-induced neuronal cell death. Hum Mol Genet. 2012 Mar 01; 21(5):1138-44. PMID: 22100763.
      Citations: 65     Fields:    Translation:AnimalsCells
    299. Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PLR, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radic Biol Med. 2012 Feb 01; 52(3):699-704. PMID: 22137893.
      Citations: 20     Fields:    Translation:HumansCells
    300. Ziats NP, Petersen RB, Lee HG, Castellani RJ, Perry G, Zhu X. Mark A. Smith, 1965-2010: consummate student of pathogenesis. Int J Clin Exp Pathol. 2011; 4(7):731-2. PMID: 22076176.
      Citations:    Fields:    Translation:HumansAnimals
    301. Castellani RJ, Gupta Y, Sheng B, Siedlak SL, Harris PL, Coller JM, Perry G, Lee HG, Tabaton M, Smith MA, Wang X, Zhu X. A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules. Lab Invest. 2011 Dec; 91(12):1777-86. PMID: 21968813.
      Citations: 17     Fields:    Translation:HumansCells
    302. Castellani RJ, Petersen RB, Lee HG, Zhu X, Perry G. Mark A. Smith: the scientist, the man. Int J Exp Pathol. 2011 Oct; 92(5):297-8. PMID: 21917030.
      Citations:    Fields:    
    303. Bonda DJ, Castellani RJ, Zhu X, Nunomura A, Lee HG, Perry G, Smith MA. A novel perspective on tau in Alzheimer's disease. Curr Alzheimer Res. 2011 Sep; 8(6):639-42. PMID: 21605042.
      Citations: 16     Fields:    Translation:HumansCells
    304. Liu Q, Xie F, Alvarado-Diaz A, Smith MA, Moreira PI, Zhu X, Perry G. Neurofilamentopathy in neurodegenerative diseases. Open Neurol J. 2011; 5:58-62. PMID: 21915226.
      Citations:    
    305. Stone JG, Siedlak SL, Tabaton M, Hirano A, Castellani RJ, Santocanale C, Perry G, Smith MA, Zhu X, Lee HG. The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies. J Neuropathol Exp Neurol. 2011 Jul; 70(7):578-87. PMID: 21666500.
      Citations: 15     Fields:    Translation:HumansCells
    306. Wang X, Su B, Liu W, He X, Gao Y, Castellani RJ, Perry G, Smith MA, Zhu X. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell. 2011 Oct; 10(5):807-23. PMID: 21615675.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    307. Valdez CM, Phelix CF, Smith MA, Perry G, Santamaria F. Modeling cholesterol metabolism by gene expression profiling in the hippocampus. Mol Biosyst. 2011 Jun; 7(6):1891-901. PMID: 21451815.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    308. Bonda DJ, Lee HG, Blair JA, Zhu X, Perry G, Smith MA. Role of metal dyshomeostasis in Alzheimer's disease. Metallomics. 2011 Mar; 3(3):267-70. PMID: 21298161.
      Citations: 78     Fields:    Translation:HumansAnimals
    309. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Res Rev. 2011 Apr; 10(2):264-73. PMID: 21262392.
      Citations: 95     Fields:    Translation:AnimalsCells
    310. Britton GB, Smith MA, Perry G, Sambamurti K, Jagannatha Rao KS. Drug discovery for neurodegenerative diseases: challenges and novel biochemical targets dedicated to the memory of Mark A. Smith for his inspiring contribution to Alzheimer's disease. J Alzheimers Dis. 2011; 24 Suppl 2:1-2. PMID: 21525570.
      Citations: 1     Fields:    Translation:Humans
    311. Stone JG, Casadesus G, Gustaw-Rothenberg K, Siedlak SL, Wang X, Zhu X, Perry G, Castellani RJ, Smith MA. Frontiers in Alzheimer's disease therapeutics. Ther Adv Chronic Dis. 2011 Jan 01; 2(1):9-23. PMID: 21743833.
      Citations:    
    312. Bonda DJ, Smith MA, Perry G, Lee HG, Wang X, Zhu X. The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention. Curr Pharm Des. 2011; 17(31):3374-80. PMID: 21902671.
      Citations: 15     Fields:    Translation:HumansCells
    313. Ashford JW, Salehi A, Furst A, Bayley P, Frisoni GB, Jack CR, Sabri O, Adamson MM, Coburn KL, Olichney J, Schuff N, Spielman D, Edland SD, Black S, Rosen A, Kennedy D, Weiner M, Perry G. Imaging the Alzheimer brain. J Alzheimers Dis. 2011; 26 Suppl 3:1-27. PMID: 21971448.
      Citations: 11     Fields:    Translation:Humans
    314. Correia SC, Cardoso S, Santos RX, Carvalho C, Santos MS, Perry G, Smith MA, Moreira PI. New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection. Curr Pharm Des. 2011; 17(31):3381-9. PMID: 21902670.
      Citations: 14     Fields:    Translation:HumansCells
    315. Perry G, Zhu X. Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease. J Alzheimers Dis. 2011; 24(1):1-2. PMID: 21383496.
      Citations:    Fields:    Translation:Humans
    316. Heath JE, Siedlak SL, Zhu X, Lee HG, Thakur A, Yan R, Perry G, Smith MA, Castellani RJ. Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology. 2010 Dec; 30(6):574-9. PMID: 20374499.
      Citations: 12     Fields:    Translation:HumansCells
    317. Perry GH, Marioni JC, Melsted P, Gilad Y. Genomic-scale capture and sequencing of endogenous DNA from feces. Mol Ecol. 2010 Dec; 19(24):5332-44. PMID: 21054605.
      Citations: 44     Fields:    Translation:Animals
    318. Stone AC, Battistuzzi FU, Kubatko LS, Perry GH, Trudeau E, Lin H, Kumar S. More reliable estimates of divergence times in Pan using complete mtDNA sequences and accounting for population structure. Philos Trans R Soc Lond B Biol Sci. 2010 Oct 27; 365(1556):3277-88. PMID: 20855302.
      Citations: 32     Fields:    Translation:AnimalsCells
    319. Castellani RJ, Nugent SL, Morrison AL, Zhu X, Lee HG, Harris PL, Bajic V, Sharma HS, Chen SG, Oettgen P, Perry G, Smith MA. CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease. J Neural Transm (Vienna). 2011 Jan; 118(1):23-6. PMID: 20972807.
      Citations: 8     Fields:    Translation:HumansCells
    320. Dwyer BE, Zacharski LR, Balestra DJ, Lerner AJ, Perry G, Zhu X, Smith MA. Potential role of iron in a Mediterranean-style diet. Arch Neurol. 2010 Oct; 67(10):1286-7; author reply 1287-8. PMID: 20937965.
      Citations: 2     Fields:    Translation:Humans
    321. Clark TA, Lee HP, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Casadesus G, Smith MA, Lee HG, Perry G. Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease. Int J Biomed Sci. 2010 Sep; 6(3):225-227. PMID: 21765811.
      Citations:    
    322. Correia SC, Carvalho C, Cardoso S, Santos RX, Santos MS, Oliveira CR, Perry G, Zhu X, Smith MA, Moreira PI. Mitochondrial preconditioning: a potential neuroprotective strategy. Front Aging Neurosci. 2010; 2. PMID: 20838473.
      Citations:    
    323. Buxton GA, Siedlak SL, Perry G, Smith MA. Mathematical modeling of microtubule dynamics: insights into physiology and disease. Prog Neurobiol. 2010 Dec; 92(4):478-83. PMID: 20713128.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    324. Valdez CM, Smith MA, Perry G, Phelix CF, Santamaria F. Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers. Hippocampus. 2010 Aug; 20(8):902-5. PMID: 20054815.
      Citations: 19     Fields:    Translation:AnimalsCells
    325. Zou WQ, Puoti G, Xiao X, Yuan J, Qing L, Cali I, Shimoji M, Langeveld JP, Castellani R, Notari S, Crain B, Schmidt RE, Geschwind M, Dearmond SJ, Cairns NJ, Dickson D, Honig L, Torres JM, Mastrianni J, Capellari S, Giaccone G, Belay ED, Schonberger LB, Cohen M, Perry G, Kong Q, Parchi P, Tagliavini F, Gambetti P. Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Ann Neurol. 2010 Aug; 68(2):162-72. PMID: 20695009.
      Citations: 96     Fields:    Translation:Humans
    326. Guglielmotto M, Aragno M, Tamagno E, Vercellinatto I, Visentin S, Medana C, Catalano MG, Smith MA, Perry G, Danni O, Boccuzzi G, Tabaton M. AGEs/RAGE complex upregulates BACE1 via NF-?B pathway activation. Neurobiol Aging. 2012 Jan; 33(1):196.e13-27. PMID: 20638753.
      Citations: 66     Fields:    Translation:AnimalsCells
    327. Moreira PI, Santos RX, Zhu X, Lee HG, Smith MA, Casadesus G, Perry G. Autophagy in Alzheimer's disease. Expert Rev Neurother. 2010 Jul; 10(7):1209-18. PMID: 20586699.
      Citations: 19     Fields:    Translation:HumansCells
    328. Storace D, Cammarata S, Borghi R, Sanguineti R, Giliberto L, Piccini A, Pollero V, Novello C, Caltagirone C, Smith MA, Boss? P, Perry G, Odetti P, Tabaton M. Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment. Arch Neurol. 2010 Jul; 67(7):867-72. PMID: 20625095.
      Citations: 15     Fields:    Translation:Humans
    329. Nakamura M, Shishido N, Nunomura A, Smith MA, Perry G, Akutsu H, Hayashi T. Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid. Free Radic Res. 2010 Jul; 44(7):734-41. PMID: 20370566.
      Citations:    Fields:    Translation:HumansCells
    330. Lee HP, Zhu X, Casadesus G, Castellani RJ, Nunomura A, Smith MA, Lee HG, Perry G. Antioxidant approaches for the treatment of Alzheimer's disease. Expert Rev Neurother. 2010 Jul; 10(7):1201-8. PMID: 20586698.
      Citations: 40     Fields:    Translation:HumansAnimals
    331. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. Int J Clin Exp Pathol. 2010 Jun 25; 3(6):570-81. PMID: 20661404.
      Citations: 55     Fields:    Translation:HumansCells
    332. Moh CF, Siedlak SL, Tabaton M, Perry G, Castellani RJ, Smith MA. Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease. J Neurosci Methods. 2010 Jul 15; 190(2):244-7. PMID: 20580647.
      Citations: 3     Fields:    Translation:Humans
    333. Mondrag?n-Rodr?guez S, Basurto-Islas G, Lee HG, Perry G, Zhu X, Castellani RJ, Smith MA. Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis. Expert Rev Neurother. 2010 May; 10(5):683-91. PMID: 20420489.
      Citations: 23     Fields:    Translation:HumansCells
    334. Poeggeler B, Sambamurti K, Siedlak SL, Perry G, Smith MA, Pappolla MA. A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. PLoS One. 2010 Apr 21; 5(4):e10206. PMID: 20421998.
      Citations: 19     Fields:    Translation:AnimalsCells
    335. Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, Smith MA. Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology. 2010 Sep-Oct; 59(4-5):290-4. PMID: 20394761.
      Citations: 174     Fields:    Translation:HumansAnimalsCells
    336. Lee HP, Zhu X, Liu G, Chen SG, Perry G, Smith MA, Lee HG. Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship. Cell Res. 2010 Apr; 20(4):397-9. PMID: 20357807.
      Citations: 11     Fields:    Translation:Humans
    337. Bonda DJ, Lee HP, Lee HG, Friedlich AL, Perry G, Zhu X, Smith MA. Novel therapeutics for Alzheimer's disease: an update. Curr Opin Drug Discov Devel. 2010 Mar; 13(2):235-46. PMID: 20205057.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    338. Bonda DJ, Wang X, Perry G, Smith MA, Zhu X. Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies. Drugs Aging. 2010 Mar 01; 27(3):181-92. PMID: 20210366.
      Citations: 37     Fields:    Translation:HumansCells
    339. Wang X, Perry G, Smith MA, Zhu X. Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons. Neurodegener Dis. 2010; 7(1-3):56-9. PMID: 20160460.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    340. Gustaw-Rothenberg K, Lerner A, Bonda DJ, Lee HG, Zhu X, Perry G, Smith MA. Biomarkers in Alzheimer's disease: past, present and future. Biomark Med. 2010 Feb; 4(1):15-26. PMID: 20387301.
      Citations: 32     Fields:    Translation:HumansCells
    341. Su B, Wang X, Bonda D, Perry G, Smith M, Zhu X. Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease? Mol Neurobiol. 2010 Jun; 41(2-3):87-96. PMID: 20101529.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    342. Avila J, Perry G, Mart?nez-Mart?n P. Prospects on the origin of Alzheimer's disease. J Alzheimers Dis. 2010; 20(2):669-72. PMID: 20505238.
      Citations: 3     Fields:    Translation:Humans
    343. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. J Alzheimers Dis. 2010; 20 Suppl 2:S401-12. PMID: 20463393.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    344. Nair NG, Perry G, Smith MA, Reddy VP. NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide. J Alzheimers Dis. 2010; 20(1):57-66. PMID: 20164601.
      Citations: 38     Fields:    Translation:HumansCells
    345. Borghi R, Piccini A, Barini E, Cirmena G, Guglielmotto M, Tamagno E, Fornaro M, Perry G, Smith MA, Garuti A, Tabaton M. Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease. J Alzheimers Dis. 2010; 22(3):771-5. PMID: 20847436.
      Citations: 10     Fields:    Translation:HumansCells
    346. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondria: the missing link between preconditioning and neuroprotection. J Alzheimers Dis. 2010; 20 Suppl 2:S475-85. PMID: 20463394.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    347. Smith MA, Zhu X, Tabaton M, Liu G, McKeel DW, Cohen ML, Wang X, Siedlak SL, Dwyer BE, Hayashi T, Nakamura M, Nunomura A, Perry G. Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis. 2010; 19(1):363-72. PMID: 20061651.
      Citations: 158     Fields:    Translation:HumansAnimalsCells
    348. Liu G, Men P, Perry G, Smith MA. Nanoparticle and iron chelators as a potential novel Alzheimer therapy. Methods Mol Biol. 2010; 610:123-44. PMID: 20013176.
      Citations: 41     Fields:    Translation:HumansCells
    349. Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease. Methods Mol Biol. 2010; 610:419-34. PMID: 20013193.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    350. Bonda DJ, Mailankot M, Stone JG, Garrett MR, Staniszewska M, Castellani RJ, Siedlak SL, Zhu X, Lee HG, Perry G, Nagaraj RH, Smith MA. Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Rep. 2010; 15(4):161-8. PMID: 20663292.
      Citations: 57     Fields:    Translation:HumansCells
    351. Bonda DJ, Wang X, Gustaw-Rothenberg KA, Perry G, Smith MA, Zhu X. Mitochondrial Drugs for Alzheimer Disease. Pharmaceuticals (Basel). 2009 Dec 23; 2(3):287-298. PMID: 20657666.
      Citations:    
    352. Cardoso S, Santos R, Correia S, Carvalho C, Zhu X, Lee HG, Casadesus G, Smith MA, Perry G, Moreira PI. Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets. Pharmaceuticals (Basel). 2009 Dec 23; 2(3):250-286. PMID: 27713238.
      Citations:    
    353. Nunomura A, Tamaoki T, Tanaka K, Motohashi N, Nakamura M, Hayashi T, Yamaguchi H, Shimohama S, Lee HG, Zhu X, Smith MA, Perry G. Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease. Neurobiol Dis. 2010 Mar; 37(3):731-7. PMID: 20034567.
      Citations: 40     Fields:    Translation:HumansCells
    354. Tabaton M, Perry G, Zhu X, Lee HG, Casadesus G, Smith MA. Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease. Am J Pathol. 2010 Feb; 176(2):540-1. PMID: 20019185.
      Citations: 1     Fields:    Translation:HumansAnimals
    355. Liu G, Men P, Perry G, Smith MA. Chapter 5 - Development of iron chelator-nanoparticle conjugates as potential therapeutic agents for Alzheimer disease. Prog Brain Res. 2009; 180:97-108. PMID: 20302830.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    356. Perry G, Moreira PI, Siedlak SL, Nunomura A, Zhu X, Smith MA. Natural oxidant balance in Parkinson disease. Arch Neurol. 2009 Dec; 66(12):1445. PMID: 20008647.
      Citations: 2     Fields:    Translation:Humans
    357. Su B, Wang X, Lee HG, Tabaton M, Perry G, Smith MA, Zhu X. Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells. Neurosci Lett. 2010 Jan 14; 468(3):267-71. PMID: 19914335.
      Citations: 79     Fields:    Translation:HumansCells
    358. Lee HP, Casadesus G, Zhu X, Lee HG, Perry G, Smith MA, Gustaw-Rothenberg K, Lerner A. All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease. Expert Rev Neurother. 2009 Nov; 9(11):1615-21. PMID: 19903021.
      Citations: 36     Fields:    Translation:HumansAnimals
    359. Crain BJ, Terry RD, Perry G. 2009 award recipients--Peter C. Burger, MD, Pierluigi Gambetti, MD, and Nicholas K. Gonatas, MD. J Neuropathol Exp Neurol. 2009 Nov; 68(11):1244-6. PMID: 19901633.
      Citations:    Fields:    Translation:Humans
    360. Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta. 2010 Jan; 1802(1):2-10. PMID: 19853658.
      Citations: 299     Fields:    Translation:HumansAnimalsCells
    361. Moreira PI, Zhu X, Wang X, Lee HG, Nunomura A, Petersen RB, Perry G, Smith MA. Mitochondria: a therapeutic target in neurodegeneration. Biochim Biophys Acta. 2010 Jan; 1802(1):212-20. PMID: 19853657.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    362. Gustaw-Rothenberg KA, Siedlak SL, Bonda DJ, Lerner A, Tabaton M, Perry G, Smith MA. Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study. Exp Gerontol. 2010 Jan; 45(1):47-52. PMID: 19819324.
      Citations: 17     Fields:    Translation:Humans
    363. Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA, Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia. J Bioenerg Biomembr. 2009 Oct; 41(5):433-40. PMID: 19830532.
      Citations: 30     Fields:    Translation:HumansCells
    364. Su B, Wang X, Zheng L, Perry G, Smith MA, Zhu X. Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochim Biophys Acta. 2010 Jan; 1802(1):135-42. PMID: 19799998.
      Citations: 125     Fields:    Translation:HumansAnimalsCells
    365. Tabaton M, Zhu X, Perry G, Smith MA, Giliberto L. Signaling effect of amyloid-beta(42) on the processing of AbetaPP. Exp Neurol. 2010 Jan; 221(1):18-25. PMID: 19747481.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    366. Su B, Liu H, Wang X, Chen SG, Siedlak SL, Kondo E, Choi R, Takeda A, Castellani RJ, Perry G, Smith MA, Zhu X, Lee HG. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Mol Neurodegener. 2009 Jul 23; 4:32. PMID: 19627592.
      Citations: 24     Fields:    
    367. Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci. 2009 Jul 15; 29(28):9090-103. PMID: 19605646.
      Citations: 623     Fields:    Translation:HumansAnimalsCells
    368. Friedlich AL, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA. Treatment advances in Alzheimer's disease based on the oxidative stress model. F1000 Med Rep. 2009 Jul 08; 1. PMID: 20948726.
      Citations:    
    369. Dwyer BE, Stone ML, Gorman N, Sinclair PR, Perry G, Smith MA, Zhu X. Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease. Neurosci Lett. 2009 Sep 25; 461(3):302-5. PMID: 19539709.
      Citations: 4     Fields:    Translation:HumansAnimals
    370. Liu G, Men P, Perry G, Smith MA. Metal chelators coupled with nanoparticles as potential therapeutic agents for Alzheimer's disease. J Nanoneurosci. 2009 Jun 01; 1(1):42-55. PMID: 19936278.
      Citations:    
    371. Dwyer BE, Smith MA, Richardson SL, Perry G, Zhu X. Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease. Neurosci Lett. 2009 Aug 28; 460(2):180-4. PMID: 19477221.
      Citations: 12     Fields:    Translation:HumansCells
    372. Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J. Tau--an inhibitor of deacetylase HDAC6 function. J Neurochem. 2009 Jun; 109(6):1756-66. PMID: 19457097.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    373. Wang X, Su B, Zheng L, Perry G, Smith MA, Zhu X. The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Neurochem. 2009 May; 109 Suppl 1:153-9. PMID: 19393022.
      Citations: 142     Fields:    Translation:HumansAnimalsCells
    374. Bonda DJ, Evans TA, Santocanale C, Llos? JC, Vi?a J, Bajic V, Castellani RJ, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging (Albany NY). 2009 Apr; 1(4):382-8. PMID: 19946466.
      Citations: 48     Fields:    Translation:HumansCells
    375. Castellani RJ, Zhu X, Lee HG, Smith MA, Perry G. Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches. Int J Mol Sci. 2009 Mar; 10(3):1386-1406. PMID: 19399255.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    376. Liu G, Men P, Kudo W, Perry G, Smith MA. Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease. Neurosci Lett. 2009 May 22; 455(3):187-90. PMID: 19429118.
      Citations: 38     Fields:    Translation:HumansCells
    377. Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol. 2009 Jul; 118(1):151-66. PMID: 19271225.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    378. Rajendran R, Minqin R, Ynsa MD, Casadesus G, Smith MA, Perry G, Halliwell B, Watt F. A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease. Biochem Biophys Res Commun. 2009 Apr 24; 382(1):91-5. PMID: 19258010.
      Citations: 33     Fields:    Translation:Animals
    379. Perry GH, Dominy NJ. Evolution of the human pygmy phenotype. Trends Ecol Evol. 2009 Apr; 24(4):218-25. PMID: 19246118.
      Citations: 54     Fields:    Translation:Humans
    380. Dwyer BE, Zacharski LR, Balestra DJ, Lerner AJ, Perry G, Zhu X, Smith MA. Getting the iron out: phlebotomy for Alzheimer's disease? Med Hypotheses. 2009 May; 72(5):504-9. PMID: 19195795.
      Citations: 12     Fields:    Translation:Humans
    381. Perry G, Zhu X, Moreira PI, Smith MA. Altered redox balance in disease: can we change the new equilibria? Ann Neurol. 2009 Feb; 65(2):121-3. PMID: 19259960.
      Citations: 2     Fields:    Translation:HumansCells
    382. Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, Perry G. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radic Res. 2009 Feb; 43(2):156-64. PMID: 19160110.
      Citations: 35     Fields:    Translation:Animals
    383. Guglielmotto M, Aragno M, Autelli R, Giliberto L, Novo E, Colombatto S, Danni O, Parola M, Smith MA, Perry G, Tamagno E, Tabaton M. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem. 2009 Feb; 108(4):1045-56. PMID: 19196431.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    384. Rolston RK, Perry G, Zhu X, Castellani RJ, Dwyer BE, Lee HG, Petersen RB, Smith MA. Iron: A Pathological Mediator of Alzheimer Disease? Agro Food Ind Hi Tech. 2009 Jan 31; 19(6):33-36. PMID: 21544251.
      Citations:    
    385. Lee HG, Casadesus G, Nunomura A, Zhu X, Castellani RJ, Richardson SL, Perry G, Felsher DW, Petersen RB, Smith MA. The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse. Am J Pathol. 2009 Mar; 174(3):891-7. PMID: 19164506.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    386. Lee HP, Zhu X, Zhu X, Skidmore SC, Perry G, Sayre LM, Smith MA, Lee HG. The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells. J Neurochem. 2009 Mar; 108(6):1434-41. PMID: 19183271.
      Citations: 7     Fields:    Translation:HumansCells
    387. Tezapsidis N, Johnston JM, Smith MA, Ashford JW, Casadesus G, Robakis NK, Wolozin B, Perry G, Zhu X, Greco SJ, Sarkar S. Leptin: a novel therapeutic strategy for Alzheimer's disease. J Alzheimers Dis. 2009; 16(4):731-40. PMID: 19387109.
      Citations: 52     Fields:    Translation:HumansAnimals
    388. Reddy VP, Zhu X, Perry G, Smith MA. Oxidative stress in diabetes and Alzheimer's disease. J Alzheimers Dis. 2009; 16(4):763-74. PMID: 19387111.
      Citations: 86     Fields:    Translation:HumansAnimals
    389. Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. J Alzheimers Dis. 2009; 18(3):483-507. PMID: 19542630.
      Citations: 25     Fields:    Translation:Humans
    390. Castellani RJ, Lee HG, Siedlak SL, Nunomura A, Hayashi T, Nakamura M, Zhu X, Perry G, Smith MA. Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. J Alzheimers Dis. 2009; 18(2):447-52. PMID: 19584435.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    391. Lee HG, Casadesus G, Zhu X, Castellani RJ, McShea A, Perry G, Petersen RB, Bajic V, Smith MA. Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease. Neurochem Int. 2009 Feb; 54(2):84-8. PMID: 19114068.
      Citations: 68     Fields:    Translation:Humans
    392. Pallas M, Camins A, Smith MA, Perry G, Lee HG, Casadesus G. From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). J Alzheimers Dis. 2008 Dec; 15(4):615-24. PMID: 19096160.
      Citations: 84     Fields:    Translation:Animals
    393. Su B, Wang X, Nunomura A, Moreira PI, Lee HG, Perry G, Smith MA, Zhu X. Oxidative stress signaling in Alzheimer's disease. Curr Alzheimer Res. 2008 Dec; 5(6):525-32. PMID: 19075578.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    394. Ramiro-Puig E, Casades?s G, Lee HG, Zhu X, McShea A, Perry G, P?rez-Cano FJ, Smith MA, Castell M. Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress. Eur J Nutr. 2009 Feb; 48(1):54-61. PMID: 19043659.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    395. Lee HG, Zhu X, Casadesus G, Pall?s M, Camins A, O'Neill MJ, Nakanishi S, Perry G, Smith MA. The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival. Brain Res. 2009 Jan 16; 1249:244-50. PMID: 19026996.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    396. Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Rev Med Chem. 2008 Nov; 8(13):1395-406. PMID: 18991755.
      Citations: 45     Fields:    Translation:HumansAnimals
    397. Stone JG, Rolston RK, Ueda M, Lee HG, Richardson SL, Castellani RJ, Perry G, Smith MA. Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain. Int J Clin Exp Pathol. 2009; 2(3):267-74. PMID: 19079621.
      Citations: 3     Fields:    
    398. Obrenovich ME, Morales LA, Cobb CJ, Shenk JC, M?ndez GM, Fischbach K, Smith MA, Qasimov EK, Perry G, Aliev G. Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation. J Cell Mol Med. 2009 May; 13(5):853-65. PMID: 19292735.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    399. Marlatt MW, Lucassen PJ, Perry G, Smith MA, Zhu X. Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies. J Alzheimers Dis. 2008 Oct; 15(2):199-210. PMID: 18953109.
      Citations: 33     Fields:    Translation:Humans
    400. Verrelli BC, Lewis CM, Stone AC, Perry GH. Different selective pressures shape the molecular evolution of color vision in chimpanzee and human populations. Mol Biol Evol. 2008 Dec; 25(12):2735-43. PMID: 18832077.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    401. Bryan KJ, Zhu X, Harris PL, Perry G, Castellani RJ, Smith MA, Casadesus G. Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease. Mol Neurodegener. 2008 Sep 11; 3:13. PMID: 18786268.
      Citations: 41     Fields:    
    402. Gelfand SL, Vento M, Sastre J, Lust WD, Smith MA, Perry G, Walsh M, Martin R. A new model of oxidative stress in rat pups. Neonatology. 2008; 94(4):293-9. PMID: 18784426.
      Citations: 5     Fields:    Translation:HumansAnimals
    403. Perry GH, Yang F, Marques-Bonet T, Murphy C, Fitzgerald T, Lee AS, Hyland C, Stone AC, Hurles ME, Tyler-Smith C, Eichler EE, Carter NP, Lee C, Redon R. Copy number variation and evolution in humans and chimpanzees. Genome Res. 2008 Nov; 18(11):1698-710. PMID: 18775914.
      Citations: 136     Fields:    Translation:HumansAnimalsCells
    404. Castellani RJ, Nunomura A, Lee HG, Perry G, Smith MA. Phosphorylated tau: toxic, protective, or none of the above. J Alzheimers Dis. 2008 Aug; 14(4):377-83. PMID: 18688087.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    405. Aliev G, Shenk JC, Fischbach K, Perry G. Stem cell niches as clinical targets: the future of anti-ischemic therapy? Nat Clin Pract Cardiovasc Med. 2008 Sep; 5(9):590-1. PMID: 18628773.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    406. Collingwood JF, Chong RK, Kasama T, Cervera-Gontard L, Dunin-Borkowski RE, Perry G, P?sfai M, Siedlak SL, Simpson ET, Smith MA, Dobson J. Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material. J Alzheimers Dis. 2008 Jun; 14(2):235-45. PMID: 18560134.
      Citations: 53     Fields:    Translation:Humans
    407. Castellani RJ, Lee HG, Zhu X, Perry G, Smith MA. Alzheimer disease pathology as a host response. J Neuropathol Exp Neurol. 2008 Jun; 67(6):523-31. PMID: 18520771.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    408. Su B, Wang X, Drew KL, Perry G, Smith MA, Zhu X. Physiological regulation of tau phosphorylation during hibernation. J Neurochem. 2008 Jun 01; 105(6):2098-108. PMID: 18284615.
      Citations: 43     Fields:    Translation:AnimalsCells
    409. Friedland RP, Tedesco JM, Wilson AC, Atwood CS, Smith MA, Perry G, Zagorski MG. Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies. J Biol Chem. 2008 Aug 15; 283(33):22550-6. PMID: 18505725.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    410. Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA. Sublethal RNA oxidation as a mechanism for neurodegenerative disease. Int J Mol Sci. 2008 May; 9(5):789-806. PMID: 19325784.
      Citations: 18     Fields:    
    411. Gustaw KA, Garrett MR, Lee HG, Castellani RJ, Zagorski MG, Prakasam A, Siedlak SL, Zhu X, Perry G, Petersen RB, Friedland RP, Smith MA. Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis. J Neurochem. 2008 Aug; 106(3):1350-6. PMID: 18485104.
      Citations: 26     Fields:    Translation:HumansAnimals
    412. Myung NH, Zhu X, Kruman II, Castellani RJ, Petersen RB, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes. Age (Dordr). 2008 Dec; 30(4):209-15. PMID: 19424844.
      Citations: 67     Fields:    
    413. Ionita-Laza I, Perry GH, Raby BA, Klanderman B, Lee C, Laird NM, Weiss ST, Lange C. On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test. Genet Epidemiol. 2008 Apr; 32(3):273-84. PMID: 18228561.
      Citations: 32     Fields:    Translation:Humans
    414. Mondrag?n-Rodr?guez S, Basurto-Islas G, Santa-Maria I, Mena R, Binder LI, Avila J, Smith MA, Perry G, Garc?a-Sierra F. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. Int J Exp Pathol. 2008 Apr; 89(2):81-90. PMID: 18336525.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    415. Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. J Cell Mol Med. 2009 Feb; 13(2):320-33. PMID: 18373733.
      Citations: 41     Fields:    Translation:AnimalsCells
    416. Shah RS, Lee HG, Xiongwei Z, Perry G, Smith MA, Castellani RJ. Current approaches in the treatment of Alzheimer's disease. Biomed Pharmacother. 2008 Apr-May; 62(4):199-207. PMID: 18407457.
      Citations: 41     Fields:    Translation:HumansPHPublic Health
    417. Perry G, Zhu X, Babar AK, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Chen SG. Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies. Neurodegener Dis. 2008; 5(3-4):222-4. PMID: 18322396.
      Citations: 17     Fields:    Translation:Humans
    418. Gonzalez-Cuyar LF, Perry G, Miyajima H, Atwood CS, Riveros-Angel M, Lyons PF, Siedlak SL, Smith MA, Castellani RJ. Redox active iron accumulation in aceruloplasminemia. Neuropathology. 2008 Oct; 28(5):466-71. PMID: 18282164.
      Citations: 18     Fields:    Translation:HumansCells
    419. Moreira PI, Santos MS, Oliveira CR, Shenk JC, Nunomura A, Smith MA, Zhu X, Perry G. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS Neurol Disord Drug Targets. 2008 Feb; 7(1):3-10. PMID: 18289026.
      Citations: 58     Fields:    Translation:HumansAnimals
    420. Perry GH, Ben-Dor A, Tsalenko A, Sampas N, Rodriguez-Revenga L, Tran CW, Scheffer A, Steinfeld I, Tsang P, Yamada NA, Park HS, Kim JI, Seo JS, Yakhini Z, Laderman S, Bruhn L, Lee C. The fine-scale and complex architecture of human copy-number variation. Am J Hum Genet. 2008 Mar; 82(3):685-95. PMID: 18304495.
      Citations: 174     Fields:    Translation:HumansCells
    421. Chan HW, Liu T, Verdile G, Bishop G, Haasl RJ, Smith MA, Perry G, Martins RN, Atwood CS. Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity. Int J Clin Exp Med. 2008; 1(1):76-88. PMID: 19079689.
      Citations:    
    422. Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radic Biol Med. 2008 Apr 15; 44(8):1493-505. PMID: 18258207.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    423. Lee AS, Guti?rrez-Arcelus M, Perry GH, Vallender EJ, Johnson WE, Miller GM, Korbel JO, Lee C. Analysis of copy number variation in the rhesus macaque genome identifies candidate loci for evolutionary and human disease studies. Hum Mol Genet. 2008 Apr 15; 17(8):1127-36. PMID: 18180252.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    424. Casadesus G, Rolston RK, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA. Menopause, estrogen, and gonadotropins in Alzheimer's disease. Adv Clin Chem. 2008; 45:139-53. PMID: 18429496.
      Citations: 4     Fields:    Translation:Humans
    425. Thakur A, Siedlak SL, James SL, Bonda DJ, Rao A, Webber KM, Camins A, Pall?s M, Casadesus G, Lee HG, Bowser R, Raina AK, Perry G, Smith MA, Zhu X. Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease. Int J Clin Exp Pathol. 2008 Jan 01; 1(2):134-46. PMID: 18784806.
      Citations: 23     Fields:    
    426. Aliev G, Gasimov E, Obrenovich ME, Fischbach K, Shenk JC, Smith MA, Perry G. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease. Vasc Health Risk Manag. 2008; 4(3):721-30. PMID: 18827923.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    427. Perry G, Castellani RJ, Moreira PI, Lee HG, Zhu X, Smith MA. Pathology's new role: defining disease process and protective responses. Int J Clin Exp Pathol. 2008 Jan 01; 1(1):1-4. PMID: 18784818.
      Citations: 1     Fields:    
    428. Sayre LM, Perry G, Smith MA. Oxidative stress and neurotoxicity. Chem Res Toxicol. 2008 Jan; 21(1):172-88. PMID: 18052107.
      Citations: 247     Fields:    Translation:HumansAnimalsCells
    429. Webber KM, Casadesus G, Bowen RL, Perry G, Smith MA. Evidence for the role of luteinizing hormone in Alzheimer disease. Endocr Metab Immune Disord Drug Targets. 2007 Dec; 7(4):300-3. PMID: 18220951.
      Citations: 7     Fields:    Translation:HumansAnimals
    430. Castellani RJ, Perry G, Smith MA. The role of novel chitin-like polysaccharides in Alzheimer disease. Neurotox Res. 2007 Dec; 12(4):269-74. PMID: 18201954.
      Citations: 18     Fields:    Translation:HumansAnimals
    431. Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA, Perry G. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. CNS Neurol Disord Drug Targets. 2007 Dec; 6(6):411-23. PMID: 18220780.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    432. Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PG, Clark RS, Clarke SG, Clav? C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Dr?ge W, Dron M, Dunn WA, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, F?s?s L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, Gonz?lez-Est?vez C, Gorski S, Gottlieb RA, H?ussinger D, He YW, Heidenreich K, Hill JA, H?yer-Hansen M, Hu X, Huang WP, Iwasaki A, J??ttel? M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JA, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kov?cs AL, Kroemer G, Kuan CY, Kumar R, Kundu M, Landry J, Laporte M, Le W, Lei HY, Lenardo MJ, Levine B, Lieberman A, Lim KL, Lin FC, Liou W, Liu LF, Lopez-Berestein G, L?pez-Ot?n C, Lu B, Macleod KF, Malorni W, Martinet W, Matsuoka K, Mautner J, Meijer AJ, Mel?ndez A, Michels P, Miotto G, Mistiaen WP, Mizushima N, Mograbi B, Monastyrska I, Moore MN, Moreira PI, Moriyasu Y, Motyl T, M?nz C, Murphy LO, Naqvi NI, Neufeld TP, Nishino I, Nixon RA, Noda T, N?rnberg B, Ogawa M, Oleinick NL, Olsen LJ, Ozpolat B, Paglin S, Palmer GE, Papassideri I, Parkes M, Perlmutter DH, Perry G, Piacentini M, Pinkas-Kramarski R, Prescott M, Proikas-Cezanne T, Raben N, Rami A, Reggiori F, Rohrer B, Rubinsztein DC, Ryan KM, Sadoshima J, Sakagami H, Sakai Y, Sandri M, Sasakawa C, Sass M, Schneider C, Seglen PO, Seleverstov O, Settleman J, Shacka JJ, Shapiro IM, Sibirny A, Silva-Zacarin EC, Simon HU, Simone C, Simonsen A, Smith MA, Spanel-Borowski K, Srinivas V, Steeves M, Stenmark H, Stromhaug PE, Subauste CS, Sugimoto S, Sulzer D, Suzuki T, Swanson MS, Tabas I, Takeshita F, Talbot NJ, Tall?czy Z, Tanaka K, Tanaka K, Tanida I, Taylor GS, Taylor JP, Terman A, Tettamanti G, Thompson CB, Thumm M, Tolkovsky AM, Tooze SA, Truant R, Tumanovska LV, Uchiyama Y, Ueno T, Uzc?tegui NL, van der Klei I, Vaquero EC, Vellai T, Vogel MW, Wang HG, Webster P, Wiley JW, Xi Z, Xiao G, Yahalom J, Yang JM, Yap G, Yin XM, Yoshimori T, Yu L, Yue Z, Yuzaki M, Zabirnyk O, Zheng X, Zhu X, Deter RL. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 2008 Feb; 4(2):151-75. PMID: 18188003.
      Citations: 1210     Fields:    Translation:HumansAnimalsCells
    433. Tamagno E, Guglielmotto M, Aragno M, Borghi R, Autelli R, Giliberto L, Muraca G, Danni O, Zhu X, Smith MA, Perry G, Jo DG, Mattson MP, Tabaton M. Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. J Neurochem. 2008 Feb; 104(3):683-95. PMID: 18005001.
      Citations: 138     Fields:    Translation:AnimalsCells
    434. Zhu X, Siedlak SL, Wang Y, Perry G, Castellani RJ, Cohen ML, Smith MA. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathol Appl Neurobiol. 2008 Aug; 34(4):457-65. PMID: 17995921.
      Citations: 38     Fields:    Translation:HumansCells
    435. Mondrag?n-Rodr?guez S, Mena R, Binder LI, Smith MA, Perry G, Garc?a-Sierra F. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology. Neuropathol Appl Neurobiol. 2008 Feb; 34(1):62-75. PMID: 17971079.
      Citations: 23     Fields:    Translation:HumansCells
    436. Nakamura M, Shishido N, Nunomura A, Smith MA, Perry G, Hayashi Y, Nakayama K, Hayashi T. Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron. Biochemistry. 2007 Nov 06; 46(44):12737-43. PMID: 17929832.
      Citations: 66     Fields:    Translation:HumansCells
    437. Webber KM, Perry G, Smith MA, Casadesus G. The contribution of luteinizing hormone to Alzheimer disease pathogenesis. Clin Med Res. 2007 Oct; 5(3):177-83. PMID: 18056027.
      Citations: 13     Fields:    Translation:HumansAnimals
    438. Liu Q, Ju WK, Crowston JG, Xie F, Perry G, Smith MA, Lindsey JD, Weinreb RN. Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4580-9. PMID: 17898281.
      Citations: 65     Fields:    Translation:AnimalsCells
    439. Wang X, Su B, Perry G, Smith MA, Zhu X. Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radic Biol Med. 2007 Dec 15; 43(12):1569-73. PMID: 18037122.
      Citations: 44     Fields:    Translation:HumansCells
    440. Perry GH, Dominy NJ, Claw KG, Lee AS, Fiegler H, Redon R, Werner J, Villanea FA, Mountain JL, Misra R, Carter NP, Lee C, Stone AC. Diet and the evolution of human amylase gene copy number variation. Nat Genet. 2007 Oct; 39(10):1256-60. PMID: 17828263.
      Citations: 544     Fields:    Translation:HumansAnimals
    441. Zhu X, Su B, Wang X, Smith MA, Perry G. Causes of oxidative stress in Alzheimer disease. Cell Mol Life Sci. 2007 Sep; 64(17):2202-10. PMID: 17605000.
      Citations: 113     Fields:    Translation:HumansCells
    442. Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G. Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J Alzheimers Dis. 2007 Sep; 12(2):195-206. PMID: 17917164.
      Citations: 75     Fields:    Translation:HumansCells
    443. Hayashi T, Shishido N, Nakayama K, Nunomura A, Smith MA, Perry G, Nakamura M. Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide. Free Radic Biol Med. 2007 Dec 01; 43(11):1552-9. PMID: 17964426.
      Citations: 28     Fields:    Translation:HumansCells
    444. Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy. 2007 Nov-Dec; 3(6):614-5. PMID: 17786024.
      Citations: 73     Fields:    Translation:HumansCells
    445. Perry GH, Martin RD, Verrelli BC. Signatures of functional constraint at aye-aye opsin genes: the potential of adaptive color vision in a nocturnal primate. Mol Biol Evol. 2007 Sep; 24(9):1963-70. PMID: 17575304.
      Citations: 18     Fields:    Translation:Animals
    446. Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol. 2007 Jun; 66(6):525-32. PMID: 17549012.
      Citations: 68     Fields:    Translation:HumansCells
    447. Thakur A, Wang X, Siedlak SL, Perry G, Smith MA, Zhu X. c-Jun phosphorylation in Alzheimer disease. J Neurosci Res. 2007 Jun; 85(8):1668-73. PMID: 17455299.
      Citations: 33     Fields:    Translation:HumansCells
    448. Castellani RJ, Moreira PI, Liu G, Dobson J, Perry G, Smith MA, Zhu X. Iron: the Redox-active center of oxidative stress in Alzheimer disease. Neurochem Res. 2007 Oct; 32(10):1640-5. PMID: 17508283.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    449. Evans TA, Raina AK, Delacourte A, Aprelikova O, Lee HG, Zhu X, Perry G, Smith MA. BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease. Int J Med Sci. 2007 May 12; 4(3):140-5. PMID: 17505559.
      Citations: 37     Fields:    Translation:HumansCells
    450. Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, Smith MA. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Rev Neurother. 2007 May; 7(5):473-85. PMID: 17492899.
      Citations: 11     Fields:    Translation:HumansAnimals
    451. Petersen RB, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA, Zhu X. Signal transduction cascades associated with oxidative stress in Alzheimer's disease. J Alzheimers Dis. 2007 May; 11(2):143-52. PMID: 17522439.
      Citations: 35     Fields:    Translation:HumansCells
    452. Zhu X, Avila J, Perry G, Smith MA. Treating the lesions, not the disease. Am J Pathol. 2007 May; 170(5):1457-9. PMID: 17456753.
      Citations: 4     Fields:    Translation:HumansAnimals
    453. Parker-Katiraee L, Carson AR, Yamada T, Arnaud P, Feil R, Abu-Amero SN, Moore GE, Kaneda M, Perry GH, Stone AC, Lee C, Meguro-Horike M, Sasaki H, Kobayashi K, Nakabayashi K, Scherer SW. Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution. PLoS Genet. 2007 May 04; 3(5):e65. PMID: 17480121.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    454. Casadesus G, Moreira PI, Nunomura A, Siedlak SL, Bligh-Glover W, Balraj E, Petot G, Smith MA, Perry G. Indices of metabolic dysfunction and oxidative stress. Neurochem Res. 2007 Apr-May; 32(4-5):717-22. PMID: 17342408.
      Citations: 9     Fields:    Translation:HumansCells
    455. Zhu X, Smith MA, Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. J Neurol Sci. 2007 Jun 15; 257(1-2):240-6. PMID: 17337008.
      Citations: 68     Fields:    Translation:HumansCells
    456. Casadesus G, Milliken EL, Webber KM, Bowen RL, Lei Z, Rao CV, Perry G, Keri RA, Smith MA. Increases in luteinizing hormone are associated with declines in cognitive performance. Mol Cell Endocrinol. 2007 Apr 15; 269(1-2):107-11. PMID: 17376589.
      Citations: 48     Fields:    Translation:Animals
    457. Wung JK, Perry G, Kowalski A, Harris PL, Bishop GM, Trivedi MA, Johnson SC, Smith MA, Denhardt DT, Atwood CS. Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. Curr Alzheimer Res. 2007 Feb; 4(1):67-72. PMID: 17316167.
      Citations: 47     Fields:    Translation:HumansCells
    458. Liu Q, Xie F, Rolston R, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Prevention and treatment of Alzheimer disease and aging: antioxidants. Mini Rev Med Chem. 2007 Feb; 7(2):171-80. PMID: 17305591.
      Citations: 18     Fields:    Translation:HumansAnimals
    459. Casadesus G, Smith MA, Basu S, Hua J, Capobianco DE, Siedlak SL, Zhu X, Perry G. Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. Mol Neurodegener. 2007 Jan 22; 2:2. PMID: 17241462.
      Citations: 16     Fields:    
    460. Lee HG, Zhu X, Castellani RJ, Nunomura A, Perry G, Smith MA. Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses. J Pharmacol Exp Ther. 2007 Jun; 321(3):823-9. PMID: 17229880.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    461. Perry GH, Tito RY, Verrelli BC. The evolutionary history of human and chimpanzee Y-chromosome gene loss. Mol Biol Evol. 2007 Mar; 24(3):853-9. PMID: 17218643.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    462. Gonzalez-Cuyar LF, Hunter B, Harris PL, Perry G, Smith MA, Castellani RJ. Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress. Redox Rep. 2007; 12(3):119-24. PMID: 17623518.
      Citations: 8     Fields:    Translation:Humans
    463. Bishop GM, Smith MA, LaManna JC, Wilson AC, Perry G, Atwood CS. Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox Rep. 2007; 12(6):257-66. PMID: 17961297.
      Citations: 5     Fields:    Translation:AnimalsCells
    464. Nunomura A, Moreira PI, Takeda A, Smith MA, Perry G. Oxidative RNA damage and neurodegeneration. Curr Med Chem. 2007; 14(28):2968-75. PMID: 18220733.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    465. Lee HG, Ueda M, Zhu X, Perry G, Smith MA. Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway? J Neurosci Res. 2006 Dec; 84(8):1856-61. PMID: 16998902.
      Citations: 33     Fields:    Translation:HumansCells
    466. Zhu X, Babar A, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Perry G, Chen SG. LRRK2 in Parkinson's disease and dementia with Lewy bodies. Mol Neurodegener. 2006 Nov 30; 1:17. PMID: 17137507.
      Citations: 20     Fields:    
    467. Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonz?lez JR, Gratac?s M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME. Global variation in copy number in the human genome. Nature. 2006 Nov 23; 444(7118):444-54. PMID: 17122850.
      Citations: 1802     Fields:    Translation:Humans
    468. Fiegler H, Redon R, Andrews D, Scott C, Andrews R, Carder C, Clark R, Dovey O, Ellis P, Feuk L, French L, Hunt P, Kalaitzopoulos D, Larkin J, Montgomery L, Perry GH, Plumb BW, Porter K, Rigby RE, Rigler D, Valsesia A, Langford C, Humphray SJ, Scherer SW, Lee C, Hurles ME, Carter NP. Accurate and reliable high-throughput detection of copy number variation in the human genome. Genome Res. 2006 Dec; 16(12):1566-74. PMID: 17122085.
      Citations: 77     Fields:    Translation:HumansCells
    469. Zhu X, Siedlak SL, Smith MA, Perry G, Chen SG. LRRK2 protein is a component of Lewy bodies. Ann Neurol. 2006 Nov; 60(5):617-618. PMID: 16847950.
      Citations: 25     Fields:    Translation:HumansCells
    470. Zhu X, Lee HG, Perry G, Smith MA. Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta. 2007 Apr; 1772(4):494-502. PMID: 17142016.
      Citations: 123     Fields:    Translation:Humans
    471. Lee HG, Ueda M, Miyamoto Y, Yoneda Y, Perry G, Smith MA, Zhu X. Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease. Brain Res. 2006 Dec 08; 1124(1):1-4. PMID: 17070506.
      Citations: 27     Fields:    Translation:HumansCells
    472. Webber KM, Casadesus G, Atwood CS, Bowen RL, Perry G, Smith MA. Gonadotropins: a cohesive gender-based etiology of Alzheimer disease. Mol Cell Endocrinol. 2007 Jan 02; 260-262:271-5. PMID: 17052835.
      Citations: 8     Fields:    Translation:Humans
    473. Webber KM, Stocco DM, Casadesus G, Bowen RL, Atwood CS, Previll LA, Harris PL, Zhu X, Perry G, Smith MA. Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease. Mol Neurodegener. 2006 Oct 03; 1:14. PMID: 17018137.
      Citations: 17     Fields:    
    474. Smith MA, Perry G. Commentary on "Perspective on a pathogenesis and treatment of Alzheimer's disease." Therapeutic strategies for Alzheimer's disease: the need for a new era of innovation. Alzheimers Dement. 2006 Oct; 2(4):294-5. PMID: 19595903.
      Citations:    Fields:    
    475. Previll LA, Crosby ME, Castellani RJ, Bowser R, Perry G, Smith MA, Zhu X. Increased expression of p130 in Alzheimer disease. Neurochem Res. 2007 Apr-May; 32(4-5):639-44. PMID: 17006760.
      Citations: 10     Fields:    Translation:HumansCells
    476. Lam-Himlin D, Espey MG, Perry G, Smith MA, Castellani RJ. Malignant glioma progression and nitric oxide. Neurochem Int. 2006 Dec; 49(8):764-8. PMID: 16971023.
      Citations: 21     Fields:    Translation:Humans
    477. Zhu X, Raina AK, Perry G, Smith MA. Apoptosis in Alzheimer disease: a mathematical improbability. Curr Alzheimer Res. 2006 Sep; 3(4):393-6. PMID: 17017869.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    478. Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose! Am J Pathol. 2006 Sep; 169(3):738-9. PMID: 16936250.
      Citations: 4     Fields:    Translation:HumansAnimalsPHPublic Health
    479. Liu G, Men P, Harris PL, Rolston RK, Perry G, Smith MA. Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance. Neurosci Lett. 2006 Oct 09; 406(3):189-93. PMID: 16919875.
      Citations: 46     Fields:    Translation:Humans
    480. Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotox Res. 2006 Aug; 10(1):43-56. PMID: 17000469.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    481. Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA. Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol. 2006 Jul; 65(7):631-41. PMID: 16825950.
      Citations: 190     Fields:    Translation:HumansAnimalsCells
    482. Zhu X, Perry G, Moreira PI, Aliev G, Cash AD, Hirai K, Smith MA. Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease. J Alzheimers Dis. 2006 Jul; 9(2):147-53. PMID: 16873962.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    483. Franco S, Blasco MA, Siedlak SL, Harris PL, Moreira PI, Perry G, Smith MA. Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy? Alzheimers Dement. 2006 Jul; 2(3):164-8. PMID: 19595878.
      Citations: 30     Fields:    
    484. Forero DA, Casadesus G, Perry G, Arboleda H. Synaptic dysfunction and oxidative stress in Alzheimer's disease: emerging mechanisms. J Cell Mol Med. 2006 Jul-Sep; 10(3):796-805. PMID: 16989739.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    485. Sparks DL, Friedland R, Petanceska S, Schreurs BG, Shi J, Perry G, Smith MA, Sharma A, Derosa S, Ziolkowski C, Stankovic G. Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology. J Nutr Health Aging. 2006 Jul-Aug; 10(4):247-54. PMID: 16886094.
      Citations: 43     Fields:    Translation:HumansAnimalsPHPublic Health
    486. Freeman JL, Perry GH, Feuk L, Redon R, McCarroll SA, Altshuler DM, Aburatani H, Jones KW, Tyler-Smith C, Hurles ME, Carter NP, Scherer SW, Lee C. Copy number variation: new insights in genome diversity. Genome Res. 2006 Aug; 16(8):949-61. PMID: 16809666.
      Citations: 331     Fields:    Translation:HumansAnimals
    487. Lee HG, Zhu X, Takeda A, Perry G, Smith MA. Emerging evidence for the neuroprotective role of alpha-synuclein. Exp Neurol. 2006 Jul; 200(1):1-7. PMID: 16780837.
      Citations: 9     Fields:    Translation:HumansAnimals
    488. Moreira PI, Zhu X, Nunomura A, Smith MA, Perry G. Therapeutic options in Alzheimer's disease. Expert Rev Neurother. 2006 Jun; 6(6):897-910. PMID: 16784412.
      Citations: 12     Fields:    Translation:Humans
    489. Aliev G, Miller JP, Leifer DW, Obrenovich ME, Shenk JC, Smith MA, Lamanna JC, Perry G, Lust DW, Cohen AR. Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system. J Submicrosc Cytol Pathol. 2006 Jun-Sep; 38(2-3):85-91. PMID: 17784635.
      Citations: 2     Fields:    Translation:AnimalsCells
    490. Smith MA, Zhu X, Lee HG, Harris PL, Fortino AE, Perry G, Castellani RJ. Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy. Age (Dordr). 2006 Mar; 28(1):85-91. PMID: 23598681.
      Citations:    Fields:    
    491. Perry GH, Tchinda J, McGrath SD, Zhang J, Picker SR, C?ceres AM, Iafrate AJ, Tyler-Smith C, Scherer SW, Eichler EE, Stone AC, Lee C. Hotspots for copy number variation in chimpanzees and humans. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8006-11. PMID: 16702545.
      Citations: 124     Fields:    Translation:HumansAnimalsCells
    492. Lee HG, Perry G, Zhu X, Nunomura A, Smith MA. Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression". Free Radic Biol Med. 2006 Jul 15; 41(2):188-9. PMID: 16814097.
      Citations: 1     Fields:    Translation:Humans
    493. Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Sci Aging Knowledge Environ. 2006 May 03; 2006(8):pe10. PMID: 16672726.
      Citations: 8     Fields:    Translation:HumansCells
    494. Castellani RJ, Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathol. 2006 Jun; 111(6):503-9. PMID: 16718346.
      Citations: 57     Fields:    Translation:Humans
    495. Hasegawa T, Matsuzaki-Kobayashi M, Takeda A, Sugeno N, Kikuchi A, Furukawa K, Perry G, Smith MA, Itoyama Y. Alpha-synuclein facilitates the toxicity of oxidized catechol metabolites: implications for selective neurodegeneration in Parkinson's disease. FEBS Lett. 2006 Apr 03; 580(8):2147-52. PMID: 16567160.
      Citations: 20     Fields:    Translation:HumansCells
    496. Moreira PI, Zhu X, Lee HG, Honda K, Smith MA, Perry G. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease. Mech Ageing Dev. 2006 Jun; 127(6):501-6. PMID: 16516950.
      Citations: 5     Fields:    Translation:HumansCells
    497. Castellani RJ, Lee HG, Perry G, Smith MA. Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau. Am J Alzheimers Dis Other Demen. 2006 Mar-Apr; 21(2):126-30. PMID: 16634469.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    498. Strocchi P, Smith MA, Perry G, Tamagno E, Danni O, Pession A, Gaiba A, Dozza B. Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells. Neurobiol Aging. 2006 Nov; 27(11):1588-94. PMID: 16464517.
      Citations: 9     Fields:    Translation:HumansCells
    499. Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid beta: the alternate hypothesis. Curr Alzheimer Res. 2006 Feb; 3(1):75-80. PMID: 16472207.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    500. Moreira PI, Honda K, Zhu X, Nunomura A, Casadesus G, Smith MA, Perry G. Brain and brawn: parallels in oxidative strength. Neurology. 2006 Jan 24; 66(2 Suppl 1):S97-101. PMID: 16432155.
      Citations: 17     Fields:    Translation:HumansCells
    501. Zhu X, Lee HG, Moreira PI, Smith MA, Perry G. Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice". Free Radic Biol Med. 2006 Mar 01; 40(5):737-9. PMID: 16520226.
      Citations:    Fields:    Translation:HumansAnimalsCells
    502. Lee HG, Zhu X, Perry G, Smith MA. The fallacy of amyloid and cognition in Alzheimer's disease. Drugs Aging. 2006; 23(2):179. PMID: 16536639.
      Citations:    Fields:    Translation:HumansAnimals
    503. Moreira PI, Zhu X, Liu Q, Honda K, Siedlak SL, Harris PL, Smith MA, Perry G. Compensatory responses induced by oxidative stress in Alzheimer disease. Biol Res. 2006; 39(1):7-13. PMID: 16629160.
      Citations: 15     Fields:    Translation:HumansCells
    504. Casadesus G, Garrett MR, Webber KM, Hartzler AW, Atwood CS, Perry G, Bowen RL, Smith MA. The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease. Drugs R D. 2006; 7(3):187-93. PMID: 16752944.
      Citations: 7     Fields:    Translation:Humans
    505. Perry G. Solving the insoluble. J Alzheimers Dis. 2006; 9(3 Suppl):301-4. PMID: 17004366.
      Citations: 3     Fields:    Translation:HumansCells
    506. Dwyer BE, Stone ML, Zhu X, Perry G, Smith MA. Heme deficiency in Alzheimer's disease: a possible connection to porphyria. J Biomed Biotechnol. 2006; 2006(3):24038. PMID: 17047301.
      Citations: 6     Fields:    
    507. Casadesus G, Puig ER, Webber KM, Atwood CS, Escuer MC, Bowen RL, Perry G, Smith MA. Targeting gonadotropins: an alternative option for Alzheimer disease treatment. J Biomed Biotechnol. 2006; 2006(3):39508. PMID: 17047306.
      Citations: 4     Fields:    
    508. Smith MA, Perry G, Zhu X, Haoudi A. Neurodegenerative diseases: mechanisms and therapies. J Biomed Biotechnol. 2006; 2006(3):47539. PMID: 17047307.
      Citations:    Fields:    
    509. Webber KM, Casadesus G, Zhu X, Obrenovich ME, Atwood CS, Perry G, Bowen RL, Smith MA. The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target. Curr Pharm Des. 2006; 12(6):691-7. PMID: 16472159.
      Citations: 7     Fields:    Translation:HumansAnimals
    510. Nunomura A, Honda K, Takeda A, Hirai K, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in neurodegenerative diseases. J Biomed Biotechnol. 2006; 2006(3):82323. PMID: 17047315.
      Citations: 48     Fields:    
    511. Perry GH, Verrelli BC, Stone AC. Molecular evolution of the primate developmental genes MSX1 and PAX9. Mol Biol Evol. 2006 Mar; 23(3):644-54. PMID: 16326750.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    512. Santa-Mar?a I, Hern?ndez F, Smith MA, Perry G, Avila J, Moreno FJ. Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers. Mol Cell Biochem. 2005 Oct; 278(1-2):203-12. PMID: 16180106.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    513. Moreira PI, Honda K, Liu Q, Santos MS, Oliveira CR, Aliev G, Nunomura A, Zhu X, Smith MA, Perry G. Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Curr Alzheimer Res. 2005 Oct; 2(4):403-8. PMID: 16248845.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    514. Castellani RJ, Siedlak SL, Fortino AE, Perry G, Ghetti B, Smith MA. Chitin-like polysaccharides in Alzheimer's disease brains. Curr Alzheimer Res. 2005 Oct; 2(4):419-23. PMID: 16248847.
      Citations: 24     Fields:    Translation:HumansCells
    515. Webber KM, Raina AK, Marlatt MW, Zhu X, Prat MI, Morelli L, Casadesus G, Perry G, Smith MA. The cell cycle in Alzheimer disease: a unique target for neuropharmacology. Mech Ageing Dev. 2005 Oct; 126(10):1019-25. PMID: 15936057.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    516. Liu G, Garrett MR, Men P, Zhu X, Perry G, Smith MA. Nanoparticle and other metal chelation therapeutics in Alzheimer disease. Biochim Biophys Acta. 2005 Sep 25; 1741(3):246-52. PMID: 16051470.
      Citations: 38     Fields:    Translation:Humans
    517. Zhu X, Moreira PI, Smith MA, Perry G. Alzheimer's disease: an intracellular movement disorder? Trends Mol Med. 2005 Sep; 11(9):391-3. PMID: 16087404.
      Citations: 6     Fields:    Translation:Animals
    518. Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, Perry G. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathol. 2005 Sep; 110(3):232-8. PMID: 16096758.
      Citations: 21     Fields:    Translation:HumansCells
    519. Lin D, Lee HG, Liu Q, Perry G, Smith MA, Sayre LM. 4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chem Res Toxicol. 2005 Aug; 18(8):1219-31. PMID: 16097795.
      Citations: 57     Fields:    Translation:HumansCells
    520. Dwyer BE, Takeda A, Zhu X, Perry G, Smith MA. Ferric cycle activity and Alzheimer disease. Curr Neurovasc Res. 2005 Jul; 2(3):261-7. PMID: 16181119.
      Citations: 2     Fields:    Translation:HumansAnimals
    521. Casadesus G, Smith MA, Perry G. Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, and Luigi Puglielli. Alzheimers Dement. 2005 Jul; 1(1):51-2. PMID: 19595817.
      Citations:    Fields:    
    522. Zhu X, Smith MA, Perry G, Wang Y, Ross AP, Zhao HW, Lamanna JC, Drew KL. MAPKs are differentially modulated in arctic ground squirrels during hibernation. J Neurosci Res. 2005 Jun 15; 80(6):862-8. PMID: 15884016.
      Citations: 18     Fields:    Translation:AnimalsCells
    523. Lee HG, Castellani RJ, Zhu X, Perry G, Smith MA. Amyloid-beta in Alzheimer's disease: the horse or the cart? Pathogenic or protective? Int J Exp Pathol. 2005 Jun; 86(3):133-8. PMID: 15910547.
      Citations: 23     Fields:    Translation:Humans
    524. Moreira PI, Smith MA, Zhu X, Nunomura A, Castellani RJ, Perry G. Oxidative stress and neurodegeneration. Ann N Y Acad Sci. 2005 Jun; 1043:545-52. PMID: 16037277.
      Citations: 59     Fields:    Translation:Humans
    525. Zhu X, Mei M, Lee HG, Wang Y, Han J, Perry G, Smith MA. P38 activation mediates amyloid-beta cytotoxicity. Neurochem Res. 2005 Jun-Jul; 30(6-7):791-6. PMID: 16187214.
      Citations: 25     Fields:    Translation:HumansCells
    526. Webber KM, Casadesus G, Marlatt MW, Perry G, Hamlin CR, Atwood CS, Bowen RL, Smith MA. Estrogen bows to a new master: the role of gonadotropins in Alzheimer pathogenesis. Ann N Y Acad Sci. 2005 Jun; 1052:201-9. PMID: 16024763.
      Citations: 17     Fields:    Translation:Humans
    527. Ashford JW, Atwood CS, Blass JP, Bowen RL, Finch CE, Iqbal K, Joseph JA, Perry G. What is aging? What is its role in Alzheimer's disease? What can we do about it? J Alzheimers Dis. 2005 Jun; 7(3):247-53; discussion 255-62. PMID: 16006669.
      Citations: 7     Fields:    Translation:HumansAnimals
    528. Barbeito L, Chun J, Binder LI, Neto VM, Perry G, Scazzochio C, Violini G. The end of a Chilean institute. Science. 2005 May 06; 308(5723):792-3. PMID: 15879193.
      Citations:    Fields:    
    529. Reddy VP, Garrett MR, Perry G, Smith MA. Carnosine: a versatile antioxidant and antiglycating agent. Sci Aging Knowledge Environ. 2005 May 04; 2005(18):pe12. PMID: 15872311.
      Citations: 41     Fields:    Translation:HumansCells
    530. Smith MA, Nunomura A, Lee HG, Zhu X, Moreira PI, Avila J, Perry G. Chronological primacy of oxidative stress in Alzheimer disease. Neurobiol Aging. 2005 May; 26(5):579-80. PMID: 15708430.
      Citations: 18     Fields:    Translation:Humans
    531. Moreira PI, Oliveira CR, Santos MS, Nunomura A, Honda K, Zhu X, Smith MA, Perry G. A second look into the oxidant mechanisms in Alzheimer's disease. Curr Neurovasc Res. 2005 Apr; 2(2):179-84. PMID: 16181112.
      Citations: 1     Fields:    Translation:HumansCells
    532. Webber KM, Casadesus G, Perry G, Atwood CS, Bowen R, Smith MA. Gender differences in Alzheimer disease: the role of luteinizing hormone in disease pathogenesis. Alzheimer Dis Assoc Disord. 2005 Apr-Jun; 19(2):95-9. PMID: 15942328.
      Citations: 10     Fields:    Translation:HumansAnimals
    533. Lee HG, Perry G, Moreira PI, Garrett MR, Liu Q, Zhu X, Takeda A, Nunomura A, Smith MA. Tau phosphorylation in Alzheimer's disease: pathogen or protector? Trends Mol Med. 2005 Apr; 11(4):164-9. PMID: 15823754.
      Citations: 79     Fields:    Translation:HumansCells
    534. Liu Q, Smith MA, Avil? J, DeBernardis J, Kansal M, Takeda A, Zhu X, Nunomura A, Honda K, Moreira PI, Oliveira CR, Santos MS, Shimohama S, Aliev G, de la Torre J, Ghanbari HA, Siedlak SL, Harris PL, Sayre LM, Perry G. Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations. Free Radic Biol Med. 2005 Mar 15; 38(6):746-54. PMID: 15721985.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    535. Honda K, Smith MA, Zhu X, Baus D, Merrick WC, Tartakoff AM, Hattier T, Harris PL, Siedlak SL, Fujioka H, Liu Q, Moreira PI, Miller FP, Nunomura A, Shimohama S, Perry G. Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron. J Biol Chem. 2005 Jun 03; 280(22):20978-86. PMID: 15767256.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    536. Webber KM, Smith MA, Lee HG, Harris PL, Moreira P, Perry G, Zhu X. Mitogen- and stress-activated protein kinase 1: convergence of the ERK and p38 pathways in Alzheimer's disease. J Neurosci Res. 2005 Feb 15; 79(4):554-60. PMID: 15635602.
      Citations: 11     Fields:    Translation:HumansCells
    537. Zhu X, Perry G, Smith MA. Insulin signaling, diabetes mellitus and risk of Alzheimer disease. J Alzheimers Dis. 2005 Feb; 7(1):81-4. PMID: 15750216.
      Citations: 13     Fields:    Translation:HumansCells
    538. Casadesus G, Atwood CS, Zhu X, Hartzler AW, Webber KM, Perry G, Bowen RL, Smith MA. Evidence for the role of gonadotropin hormones in the development of Alzheimer disease. Cell Mol Life Sci. 2005 Feb; 62(3):293-8. PMID: 15723165.
      Citations: 14     Fields:    Translation:Humans
    539. Tamagno E, Parola M, Bardini P, Piccini A, Borghi R, Guglielmotto M, Santoro G, Davit A, Danni O, Smith MA, Perry G, Tabaton M. Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways. J Neurochem. 2005 Feb; 92(3):628-36. PMID: 15659232.
      Citations: 132     Fields:    Translation:HumansCells
    540. Yuan J, Kinter M, McGeehan J, Perry G, Kneale G, Gambetti P, Zou WQ. Concealment of epitope by reduction and alkylation in prion protein. Biochem Biophys Res Commun. 2005 Jan 21; 326(3):652-9. PMID: 15596149.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    541. Liu Q, Lee HG, Honda K, Siedlak SL, Harris PL, Cash AD, Zhu X, Avila J, Nunomura A, Takeda A, Smith MA, Perry G. Tau modifiers as therapeutic targets for Alzheimer's disease. Biochim Biophys Acta. 2005 Jan 03; 1739(2-3):211-5. PMID: 15615639.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    542. Moreira PI, Smith MA, Zhu X, Honda K, Lee HG, Aliev G, Perry G. Oxidative damage and Alzheimer's disease: are antioxidant therapies useful? Drug News Perspect. 2005 Jan-Feb; 18(1):13-9. PMID: 15753972.
      Citations: 7     Fields:    Translation:HumansAnimals
    543. Marlatt MW, Webber KM, Moreira PI, Lee HG, Casadesus G, Honda K, Zhu X, Perry G, Smith MA. Therapeutic opportunities in Alzheimer disease: one for all or all for one? Curr Med Chem. 2005; 12(10):1137-47. PMID: 15892629.
      Citations: 15     Fields:    Translation:HumansAnimals
    544. Zhu X, Lee HG, Casadesus G, Avila J, Drew K, Perry G, Smith MA. Oxidative imbalance in Alzheimer's disease. Mol Neurobiol. 2005; 31(1-3):205-17. PMID: 15953822.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    545. Sayre LM, Moreira PI, Smith MA, Perry G. Metal ions and oxidative protein modification in neurological disease. Ann Ist Super Sanita. 2005; 41(2):143-64. PMID: 16244388.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    546. Sahin M, Karauzum SB, Perry G, Smith MA, Aliciguzel Y. Retinoic acid isomers protect hippocampal neurons from amyloid-beta induced neurodegeneration. Neurotox Res. 2005; 7(3):243-50. PMID: 15897158.
      Citations: 10     Fields:    Translation:AnimalsCells
    547. Aliyev A, Chen SG, Seyidova D, Smith MA, Perry G, de la Torre J, Aliev G. Mitochondria DNA deletions in atherosclerotic hypoperfused brain microvessels as a primary target for the development of Alzheimer's disease. J Neurol Sci. 2005 Mar 15; 229-230:285-92. PMID: 15760652.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    548. Santa-Mar?a I, Smith MA, Perry G, Hern?ndez F, Avila J, Moreno FJ. Effect of quinones on microtubule polymerization: a link between oxidative stress and cytoskeletal alterations in Alzheimer's disease. Biochim Biophys Acta. 2005 Jun 10; 1740(3):472-80. PMID: 15949717.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    549. Moreira PI, Siedlak SL, Aliev G, Zhu X, Cash AD, Smith MA, Perry G. Oxidative stress mechanisms and potential therapeutics in Alzheimer disease. J Neural Transm (Vienna). 2005 Jul; 112(7):921-32. PMID: 15583960.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    550. Liu Q, Xie F, Siedlak SL, Nunomura A, Honda K, Moreira PI, Zhua X, Smith MA, Perry G. Neurofilament proteins in neurodegenerative diseases. Cell Mol Life Sci. 2004 Dec; 61(24):3057-75. PMID: 15583867.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    551. Lee HG, Moreira PI, Zhu X, Smith MA, Perry G. Staying connected: synapses in Alzheimer disease. Am J Pathol. 2004 Nov; 165(5):1461-4. PMID: 15509517.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    552. Zhu X, Smith MA, Perry G, Aliev G. Mitochondrial failures in Alzheimer's disease. Am J Alzheimers Dis Other Demen. 2004 Nov-Dec; 19(6):345-52. PMID: 15633943.
      Citations: 45     Fields:    Translation:HumansCells
    553. Moreira PI, Smith MA, Zhu X, Santos MS, Oliveira CR, Perry G. Therapeutic potential of oxidant mechanisms in Alzheimer's disease. Expert Rev Neurother. 2004 Nov; 4(6):995-1004. PMID: 15853526.
      Citations: 2     Fields:    Translation:HumansAnimals
    554. de la Torre J, Aliev G, Perry G. Drug therapy in Alzheimer's disease. N Engl J Med. 2004 Oct 28; 351(18):1911-3; author reply 1911-3. PMID: 15509830.
      Citations: 5     Fields:    Translation:Humans
    555. Nunomura A, Chiba S, Lippa CF, Cras P, Kalaria RN, Takeda A, Honda K, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease. Neurobiol Dis. 2004 Oct; 17(1):108-13. PMID: 15350971.
      Citations: 59     Fields:    Translation:HumansCells
    556. Takeda A, Itoyama Y, Kimpara T, Zhu X, Avila J, Dwyer BE, Perry G, Smith MA. Heme catabolism and heme oxygenase in neurodegenerative disease. Antioxid Redox Signal. 2004 Oct; 6(5):888-94. PMID: 15345149.
      Citations: 11     Fields:    Translation:HumansCells
    557. Aliev G, Smith MA, de la Torre JC, Perry G. Mitochondria as a primary target for vascular hypoperfusion and oxidative stress in Alzheimer's disease. Mitochondrion. 2004 Sep; 4(5-6):649-63. PMID: 16120422.
      Citations: 31     Fields:    
    558. Casadesus G, Zhu X, Atwood CS, Webber KM, Perry G, Bowen RL, Smith MA. Beyond estrogen: targeting gonadotropin hormones in the treatment of Alzheimer's disease. Curr Drug Targets CNS Neurol Disord. 2004 Aug; 3(4):281-5. PMID: 15379604.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    559. Zhu X, Webber KM, Casadesus G, Raina AK, Lee HG, Marlatt M, Hartzler A, Atwood CS, Perry G, Smith MA. Mitotic and gender parallels in Alzheimer disease: therapeutic opportunities. Curr Drug Targets. 2004 Aug; 5(6):559-63. PMID: 15270202.
      Citations: 2     Fields:    Translation:HumansAnimals
    560. Hasegawa T, Matsuzaki M, Takeda A, Kikuchi A, Akita H, Perry G, Smith MA, Itoyama Y. Accelerated alpha-synuclein aggregation after differentiation of SH-SY5Y neuroblastoma cells. Brain Res. 2004 Jul 02; 1013(1):51-9. PMID: 15196967.
      Citations: 19     Fields:    Translation:HumansCells
    561. Castellani RJ, Honda K, Zhu X, Cash AD, Nunomura A, Perry G, Smith MA. Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease. Ageing Res Rev. 2004 Jul; 3(3):319-26. PMID: 15231239.
      Citations: 23     Fields:    Translation:HumansCells
    562. Aliyev A, Seyidova D, Rzayev N, Obrenovich ME, Lamb BT, Chen SG, Smith MA, Perry G, de la Torre JC, Aliev G. Is nitric oxide a key target in the pathogenesis of brain lesions during the development of Alzheimer's disease? Neurol Res. 2004 Jul; 26(5):547-53. PMID: 15265272.
      Citations: 11     Fields:    Translation:HumansAnimals
    563. Aliev G, Castellani RJ, Petersen RB, Burnstock G, Perry G, Smith MA. Pathobiology of familial hypercholesterolemic atherosclerosis. J Submicrosc Cytol Pathol. 2004 Jul-Oct; 36(3-4):225-40. PMID: 15906597.
      Citations: 7     Fields:    Translation:HumansAnimals
    564. Lee HG, Casadesus G, Zhu X, Takeda A, Perry G, Smith MA. Challenging the amyloid cascade hypothesis: senile plaques and amyloid-beta as protective adaptations to Alzheimer disease. Ann N Y Acad Sci. 2004 Jun; 1019:1-4. PMID: 15246983.
      Citations: 57     Fields:    Translation:HumansCells
    565. Zhu X, Wang Y, Ogawa O, Lee HG, Raina AK, Siedlak SL, Harris PL, Fujioka H, Shimohama S, Tabaton M, Atwood CS, Petersen RB, Perry G, Smith MA. Neuroprotective properties of Bcl-w in Alzheimer disease. J Neurochem. 2004 Jun; 89(5):1233-40. PMID: 15147516.
      Citations: 19     Fields:    Translation:HumansCells
    566. Sayre LM, Harris PL, Perry G, Smith MA. In situ localization of nonenzymatic peroxidase-like activity of tissue-bound transition metals. Curr Protoc Toxicol. 2004 Jun; Chapter 17:Unit17.4. PMID: 23045100.
      Citations:    Fields:    Translation:Cells
    567. Dwyer BE, Raina AK, Perry G, Smith MA. Homocysteine and Alzheimer's disease: a modifiable risk? Free Radic Biol Med. 2004 Jun 01; 36(11):1471-5. PMID: 15135184.
      Citations: 21     Fields:    Translation:Humans
    568. Dozza B, Smith MA, Perry G, Tabaton M, Strocchi P. Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells. J Neurochem. 2004 Jun; 89(5):1224-32. PMID: 15147515.
      Citations: 17     Fields:    Translation:HumansCells
    569. Kang SC, Brown DR, Whiteman M, Li R, Pan T, Perry G, Wisniewski T, Sy MS, Wong BS. Prion protein is ubiquitinated after developing protease resistance in the brains of scrapie-infected mice. J Pathol. 2004 May; 203(1):603-8. PMID: 15095484.
      Citations: 23     Fields:    Translation:Animals
    570. Castellani RJ, Smith MA, Perry G, Friedland RP. Cerebral amyloid angiopathy: major contributor or decorative response to Alzheimer's disease pathogenesis. Neurobiol Aging. 2004 May-Jun; 25(5):599-602; discussion 603-4. PMID: 15172735.
      Citations: 23     Fields:    Translation:HumansAnimals
    571. Seyidova D, Aliyev A, Rzayev N, Obrenovich M, Lamb BT, Smith MA, de la Torre JC, Perry G, Aliev G. The role of nitric oxide in the pathogenesis of brain lesions during the development of Alzheimer's disease. In Vivo. 2004 May-Jun; 18(3):325-33. PMID: 15341188.
      Citations: 10     Fields:    Translation:HumansAnimals
    572. Avila J, P?rez M, Lucas JJ, G?mez-Ramos A, Santa Mar?a I, Moreno F, Smith M, Perry G, Hern?ndez F. Assembly in vitro of tau protein and its implications in Alzheimer's disease. Curr Alzheimer Res. 2004 May; 1(2):97-101. PMID: 15975073.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    573. Zhu X, Raina AK, Perry G, Smith MA. Alzheimer's disease: the two-hit hypothesis. Lancet Neurol. 2004 Apr; 3(4):219-26. PMID: 15039034.
      Citations: 149     Fields:    Translation:HumansAnimalsCells
    574. Lee HG, Casadesus G, Zhu X, Joseph JA, Perry G, Smith MA. Perspectives on the amyloid-beta cascade hypothesis. J Alzheimers Dis. 2004 Apr; 6(2):137-45. PMID: 15096697.
      Citations: 12     Fields:    Translation:HumansCells
    575. Casadesus G, Smith MA, Zhu X, Aliev G, Cash AD, Honda K, Petersen RB, Perry G. Alzheimer disease: evidence for a central pathogenic role of iron-mediated reactive oxygen species. J Alzheimers Dis. 2004 Apr; 6(2):165-9. PMID: 15096700.
      Citations: 41     Fields:    Translation:HumansCells
    576. Zhu X, Raina AK, Lee HG, Casadesus G, Smith MA, Perry G. Oxidative stress signalling in Alzheimer's disease. Brain Res. 2004 Mar 12; 1000(1-2):32-9. PMID: 15053949.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    577. Honda K, Casadesus G, Petersen RB, Perry G, Smith MA. Oxidative stress and redox-active iron in Alzheimer's disease. Ann N Y Acad Sci. 2004 Mar; 1012:179-82. PMID: 15105265.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    578. Zhu X, McShea A, Harris PL, Raina AK, Castellani RJ, Funk JO, Shah S, Atwood C, Bowen R, Bowser R, Morelli L, Perry G, Smith MA. Elevated expression of a regulator of the G2/M phase of the cell cycle, neuronal CIP-1-associated regulator of cyclin B, in Alzheimer's disease. J Neurosci Res. 2004 Mar 01; 75(5):698-703. PMID: 14991845.
      Citations: 30     Fields:    Translation:HumansCells
    579. Lee HG, Ogawa O, Zhu X, O'Neill MJ, Petersen RB, Castellani RJ, Ghanbari H, Perry G, Smith MA. Aberrant expression of metabotropic glutamate receptor 2 in the vulnerable neurons of Alzheimer's disease. Acta Neuropathol. 2004 Apr; 107(4):365-71. PMID: 14872255.
      Citations: 31     Fields:    Translation:HumansCells
    580. Bowen RL, Verdile G, Liu T, Parlow AF, Perry G, Smith MA, Martins RN, Atwood CS. Luteinizing hormone, a reproductive regulator that modulates the processing of amyloid-beta precursor protein and amyloid-beta deposition. J Biol Chem. 2004 May 07; 279(19):20539-45. PMID: 14871891.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    581. Ghanbari HA, Ghanbari K, Harris PL, Jones PK, Kubat Z, Castellani RJ, Wolozin BL, Smith MA, Perry G. Oxidative damage in cultured human olfactory neurons from Alzheimer's disease patients. Aging Cell. 2004 02; 3(1):41-4. PMID: 14965355.
      Citations: 24     Fields:    Translation:HumansCells
    582. Liu T, Perry G, Chan HW, Verdile G, Martins RN, Smith MA, Atwood CS. Amyloid-beta-induced toxicity of primary neurons is dependent upon differentiation-associated increases in tau and cyclin-dependent kinase 5 expression. J Neurochem. 2004 Feb; 88(3):554-63. PMID: 14720205.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    583. Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, Smith MA, Chen SG, Bush AI. Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta. Biochemistry. 2004 Jan 20; 43(2):560-8. PMID: 14717612.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    584. G?mez-Ramos A, Smith MA, Perry G, Avila J. Tau phosphorylation and assembly. Acta Neurobiol Exp (Wars). 2004; 64(1):33-9. PMID: 15190678.
      Citations: 12     Fields:    Translation:HumansCells
    585. Webber KM, Bowen R, Casadesus G, Perry G, Atwood CS, Smith MA. Gonadotropins and Alzheimer's disease: the link between estrogen replacement therapy and neuroprotection. Acta Neurobiol Exp (Wars). 2004; 64(1):113-8. PMID: 15190686.
      Citations: 8     Fields:    Translation:Humans
    586. Castellani RJ, Perry G, Smith MA. Prion disease and Alzheimer's disease: pathogenic overlap. Acta Neurobiol Exp (Wars). 2004; 64(1):11-7. PMID: 15190676.
      Citations: 6     Fields:    Translation:Humans
    587. Marlatt M, Lee HG, Perry G, Smith MA, Zhu X. Sources and mechanisms of cytoplasmic oxidative damage in Alzheimer's disease. Acta Neurobiol Exp (Wars). 2004; 64(1):81-7. PMID: 15190682.
      Citations: 16     Fields:    Translation:HumansCells
    588. Lee HG, Zhu X, O'Neill MJ, Webber K, Casadesus G, Marlatt M, Raina AK, Perry G, Smith MA. The role of metabotropic glutamate receptors in Alzheimer's disease. Acta Neurobiol Exp (Wars). 2004; 64(1):89-98. PMID: 15190683.
      Citations: 23     Fields:    Translation:Humans
    589. Perry G, Nunomura A, Raina AK, Aliev G, Siedlak SL, Harris PL, Casadesus G, Petersen RB, Bligh-Glover W, Balraj E, Petot GJ, Smith MA. A metabolic basis for Alzheimer disease. Neurochem Res. 2003 Oct; 28(10):1549-52. PMID: 14570400.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    590. Zhu X, Raina AK, Lee HG, Chao M, Nunomura A, Tabaton M, Petersen RB, Perry G, Smith MA. Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways. Antioxid Redox Signal. 2003 Oct; 5(5):571-6. PMID: 14580312.
      Citations: 25     Fields:    Translation:HumansCells
    591. Lee HG, Petersen RB, Zhu X, Honda K, Aliev G, Smith MA, Perry G. Will preventing protein aggregates live up to its promise as prophylaxis against neurodegenerative diseases? Brain Pathol. 2003 Oct; 13(4):630-8. PMID: 14655766.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    592. Atwood CS, Bowen RL, Smith MA, Perry G. Cerebrovascular requirement for sealant, anti-coagulant and remodeling molecules that allow for the maintenance of vascular integrity and blood supply. Brain Res Brain Res Rev. 2003 Sep; 43(1):164-78. PMID: 14499467.
      Citations: 26     Fields:    Translation:HumansAnimals
    593. Aliev G, Seyidova D, Lamb BT, Obrenovich ME, Siedlak SL, Vinters HV, Friedland RP, LaManna JC, Smith MA, Perry G. Mitochondria and vascular lesions as a central target for the development of Alzheimer's disease and Alzheimer disease-like pathology in transgenic mice. Neurol Res. 2003 Sep; 25(6):665-74. PMID: 14503022.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    594. Atwood CS, Obrenovich ME, Liu T, Chan H, Perry G, Smith MA, Martins RN. Amyloid-beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta. Brain Res Brain Res Rev. 2003 Sep; 43(1):1-16. PMID: 14499458.
      Citations: 84     Fields:    Translation:HumansAnimals
    595. Perry G, Castellani RJ, Smith MA, Harris PL, Kubat Z, Ghanbari K, Jones PK, Cordone G, Tabaton M, Wolozin B, Ghanbari H. Oxidative damage in the olfactory system in Alzheimer's disease. Acta Neuropathol. 2003 Dec; 106(6):552-6. PMID: 12955399.
      Citations: 19     Fields:    Translation:HumansCells
    596. Kitamura Y, Tsuchiya D, Takata K, Shibagaki K, Taniguchi T, Smith MA, Perry G, Miki H, Takenawa T, Shimohama S. Possible involvement of Wiskott-Aldrich syndrome protein family in aberrant neuronal sprouting in Alzheimer's disease. Neurosci Lett. 2003 Aug 07; 346(3):149-52. PMID: 12853106.
      Citations: 8     Fields:    Translation:HumansCells
    597. Liu Q, Raina AK, Smith MA, Sayre LM, Perry G. Hydroxynonenal, toxic carbonyls, and Alzheimer disease. Mol Aspects Med. 2003 Aug-Oct; 24(4-5):305-13. PMID: 12893008.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    598. Zhu X, Sun Z, Lee HG, Siedlak SL, Perry G, Smith MA. Distribution, levels, and activation of MEK1 in Alzheimer's disease. J Neurochem. 2003 Jul; 86(1):136-42. PMID: 12807433.
      Citations: 22     Fields:    Translation:HumansCells
    599. Aliev G, Obrenovich ME, Seyidova D, Rzayev NM, Aliyev AS, Raina AK, Lamanna JC, Smith MA, Perry G. X-ray contrast media induce aortic endothelial damage, which can be prevented with prior heparin treatment. J Submicrosc Cytol Pathol. 2003 Jul; 35(3):253-66. PMID: 14690173.
      Citations: 7     Fields:    Translation:Animals
    600. Matsubara E, Bryant-Thomas T, Pacheco Quinto J, Henry TL, Poeggeler B, Herbert D, Cruz-Sanchez F, Chyan YJ, Smith MA, Perry G, Shoji M, Abe K, Leone A, Grundke-Ikbal I, Wilson GL, Ghiso J, Williams C, Refolo LM, Pappolla MA, Chain DG, Neria E. Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease. J Neurochem. 2003 Jun; 85(5):1101-8. PMID: 12753069.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    601. Bruckner SR, Perry G, Estus S. 4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis. J Neurochem. 2003 May; 85(4):999-1005. PMID: 12716431.
      Citations: 6     Fields:    Translation:AnimalsCells
    602. Cash AD, Aliev G, Siedlak SL, Nunomura A, Fujioka H, Zhu X, Raina AK, Vinters HV, Tabaton M, Johnson AB, Paula-Barbosa M, Av?la J, Jones PK, Castellani RJ, Smith MA, Perry G. Microtubule reduction in Alzheimer's disease and aging is independent of tau filament formation. Am J Pathol. 2003 May; 162(5):1623-7. PMID: 12707046.
      Citations: 122     Fields:    Translation:HumansCells
    603. Bianco NR, Perry G, Smith MA, Templeton DJ, Montano MM. Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Mol Endocrinol. 2003 Jul; 17(7):1344-55. PMID: 12714703.
      Citations: 17     Fields:    Translation:HumansCells
    604. Veurink G, Liu D, Taddei K, Perry G, Smith MA, Robertson TA, Hone E, Groth DM, Atwood CS, Martins RN. Reduction of inclusion body pathology in ApoE-deficient mice fed a combination of antioxidants. Free Radic Biol Med. 2003 Apr 15; 34(8):1070-7. PMID: 12684092.
      Citations: 15     Fields:    Translation:AnimalsCells
    605. Raina AK, Hochman A, Ickes H, Zhu X, Ogawa O, Cash AD, Shimohama S, Perry G, Smith MA. Apoptotic promoters and inhibitors in Alzheimer's disease: Who wins out? Prog Neuropsychopharmacol Biol Psychiatry. 2003 Apr; 27(2):251-4. PMID: 12657364.
      Citations: 20     Fields:    Translation:Humans
    606. Ogawa O, Lee HG, Zhu X, Raina A, Harris PL, Castellani RJ, Perry G, Smith MA. Increased p27, an essential component of cell cycle control, in Alzheimer's disease. Aging Cell. 2003 04; 2(2):105-10. PMID: 12882323.
      Citations: 38     Fields:    Translation:HumansCells
    607. Zhu X, Ogawa O, Wang Y, Perry G, Smith MA. JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease. J Neurochem. 2003 Apr; 85(1):87-93. PMID: 12641730.
      Citations: 19     Fields:    Translation:HumansCells
    608. Dong J, Atwood CS, Anderson VE, Siedlak SL, Smith MA, Perry G, Carey PR. Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence. Biochemistry. 2003 Mar 18; 42(10):2768-73. PMID: 12627941.
      Citations: 159     Fields:    Translation:HumansCells
    609. G?mez-Ramos A, D?az-Nido J, Smith MA, Perry G, Avila J. Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells. J Neurosci Res. 2003 Mar 15; 71(6):863-70. PMID: 12605413.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    610. Smith MA, Perry G, Atwood CS, Bowen RL. Estrogen replacement and risk of Alzheimer disease. JAMA. 2003 Mar 05; 289(9):1100; author reply 1101-2. PMID: 12622570.
      Citations: 6     Fields:    Translation:Humans
    611. Tateyama M, Takeda A, Onodera Y, Matsuzaki M, Hasegawa T, Nunomura A, Hirai K, Perry G, Smith MA, Itoyama Y. Oxidative stress and predominant Abeta42(43) deposition in myopathies with rimmed vacuoles. Acta Neuropathol. 2003 Jun; 105(6):581-5. PMID: 12734664.
      Citations: 12     Fields:    Translation:HumansCells
    612. Perry G, Taddeo MA, Petersen RB, Castellani RJ, Harris PL, Siedlak SL, Cash AD, Liu Q, Nunomura A, Atwood CS, Smith MA. Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease. Biometals. 2003 Mar; 16(1):77-81. PMID: 12572666.
      Citations: 31     Fields:    Translation:HumansCells
    613. Ogawa O, Zhu X, Lee HG, Raina A, Obrenovich ME, Bowser R, Ghanbari HA, Castellani RJ, Perry G, Smith MA. Ectopic localization of phosphorylated histone H3 in Alzheimer's disease: a mitotic catastrophe? Acta Neuropathol. 2003 May; 105(5):524-8. PMID: 12677454.
      Citations: 71     Fields:    Translation:HumansCells
    614. Atwood CS, Perry G, Smith MA. Cerebral hemorrhage and amyloid-beta. Science. 2003 Feb 14; 299(5609):1014; author reply 1014. PMID: 12586924.
      Citations: 5     Fields:    Translation:HumansAnimals
    615. Takata K, Kitamura Y, Kakimura J, Shibagaki K, Tsuchiya D, Taniguchi T, Smith MA, Perry G, Shimohama S. Role of high mobility group protein-1 (HMG1) in amyloid-beta homeostasis. Biochem Biophys Res Commun. 2003 Feb 14; 301(3):699-703. PMID: 12565837.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    616. Zhu X, Perry G, Smith MA. Amyotrophic lateral sclerosis: a novel hypothesis involving a gained 'loss of function' in the JNK/SAPK pathway. Redox Rep. 2003; 8(3):129-33. PMID: 12935309.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    617. Aliev G, Smith MA, Obrenovich ME, de la Torre JC, Perry G. Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease. Neurotox Res. 2003; 5(7):491-504. PMID: 14715433.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    618. Aliev G, Obrenovich ME, Smith MA, Perry G. Hypoperfusion, Mitochondria Failure, Oxidative Stress, and Alzheimer Disease. J Biomed Biotechnol. 2003; 2003(3):162-163. PMID: 12975531.
      Citations: 12     Fields:    
    619. Raina AK, Zhu X, Shimohama S, Perry G, Smith MA. Tipping the apoptotic balance in Alzheimer's disease: the abortosis concept. Cell Biochem Biophys. 2003; 39(3):249-55. PMID: 14716079.
      Citations: 6     Fields:    Translation:HumansCells
    620. Perry G, Nunomura A, Hirai K, Zhu X, P?rez M, Avila J, Castellani RJ, Atwood CS, Aliev G, Sayre LM, Takeda A, Smith MA. Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases? Free Radic Biol Med. 2002 Dec 01; 33(11):1475-9. PMID: 12446204.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    621. Drew KL, T?ien ?, Rivera PM, Smith MA, Perry G, Rice ME. Role of the antioxidant ascorbate in hibernation and warming from hibernation. Comp Biochem Physiol C Toxicol Pharmacol. 2002 Dec; 133(4):483-92. PMID: 12458177.
      Citations: 29     Fields:    Translation:HumansAnimals
    622. Perry G, Taddeo MA, Nunomura A, Zhu X, Zenteno-Savin T, Drew KL, Shimohama S, Avila J, Castellani RJ, Smith MA. Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response. Comp Biochem Physiol C Toxicol Pharmacol. 2002 Dec; 133(4):507-13. PMID: 12458179.
      Citations: 16     Fields:    Translation:HumansAnimals
    623. Nunomura A, Chiba S, Kosaka K, Takeda A, Castellani RJ, Smith MA, Perry G. Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies. Neuroreport. 2002 Nov 15; 13(16):2035-9. PMID: 12438921.
      Citations: 34     Fields:    Translation:Humans
    624. Bowen RL, Smith MA, Harris PL, Kubat Z, Martins RN, Castellani RJ, Perry G, Atwood CS. Elevated luteinizing hormone expression colocalizes with neurons vulnerable to Alzheimer's disease pathology. J Neurosci Res. 2002 Nov 01; 70(3):514-8. PMID: 12391612.
      Citations: 28     Fields:    Translation:HumansCells
    625. Obrenovich ME, Joseph JA, Atwood CS, Perry G, Smith MA. Amyloid-beta: a (life) preserver for the brain. Neurobiol Aging. 2002 Nov-Dec; 23(6):1097-9. PMID: 12470809.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    626. Atwood CS, Bishop GM, Perry G, Smith MA. Amyloid-beta: a vascular sealant that protects against hemorrhage? J Neurosci Res. 2002 Nov 01; 70(3):356. PMID: 12391596.
      Citations: 12     Fields:    Translation:HumansAnimalsPHPublic Health
    627. Castellani R, Hirai K, Aliev G, Drew KL, Nunomura A, Takeda A, Cash AD, Obrenovich ME, Perry G, Smith MA. Role of mitochondrial dysfunction in Alzheimer's disease. J Neurosci Res. 2002 Nov 01; 70(3):357-60. PMID: 12391597.
      Citations: 129     Fields:    Translation:HumansAnimalsCells
    628. Aliev G, Seyidova D, Neal ML, Shi J, Lamb BT, Siedlak SL, Vinters HV, Head E, Perry G, Lamanna JC, Friedland RP, Cotman CW. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels as a central target for the development of human AD and AD-like pathology in aged transgenic mice. Ann N Y Acad Sci. 2002 Nov; 977:45-64. PMID: 12480733.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    629. Smith MA, Casadesus G, Joseph JA, Perry G. Amyloid-beta and tau serve antioxidant functions in the aging and Alzheimer brain. Free Radic Biol Med. 2002 Nov 01; 33(9):1194-9. PMID: 12398927.
      Citations: 56     Fields:    Translation:HumansCells
    630. Kakimura J, Kitamura Y, Takata K, Tsuchiya D, Taniguchi T, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Possible involvement of ER chaperone Grp78 on reduced formation of amyloid-beta deposits. Ann N Y Acad Sci. 2002 Nov; 977:327-32. PMID: 12480769.
      Citations: 9     Fields:    Translation:HumansCells
    631. Takata K, Kitamura Y, Kakimura J, Shibagaki K, Taniguchi T, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Possible protective mechanisms of heme oxygenase-1 in the brain. Ann N Y Acad Sci. 2002 Nov; 977:501-6. PMID: 12480792.
      Citations: 4     Fields:    Translation:HumansCells
    632. Ogawa O, Zhu X, Perry G, Smith MA. Mitochondrial abnormalities and oxidative imbalance in neurodegenerative disease. Sci Aging Knowledge Environ. 2002 Oct 16; 2002(41):pe16. PMID: 14603007.
      Citations: 11     Fields:    Translation:HumansCells
    633. Cash AD, Perry G, Ogawa O, Raina AK, Zhu X, Smith MA. Is Alzheimer's disease a mitochondrial disorder? Neuroscientist. 2002 Oct; 8(5):489-96. PMID: 12374431.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    634. Hartzler AW, Zhu X, Siedlak SL, Castellani RJ, Avil? J, Perry G, Smith MA. The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau. Neurobiol Aging. 2002 Sep-Oct; 23(5):855-9. PMID: 12392790.
      Citations: 14     Fields:    Translation:HumansCells
    635. Lee HG, Zhu X, Ghanbari HA, Ogawa O, Raina AK, O'Neill MJ, Perry G, Smith MA. Differential regulation of glutamate receptors in Alzheimer's disease. Neurosignals. 2002 Sep-Oct; 11(5):282-92. PMID: 12566929.
      Citations: 10     Fields:    Translation:HumansAnimals
    636. Zhu X, Lee HG, Raina AK, Perry G, Smith MA. The role of mitogen-activated protein kinase pathways in Alzheimer's disease. Neurosignals. 2002 Sep-Oct; 11(5):270-81. PMID: 12566928.
      Citations: 150     Fields:    Translation:HumansAnimalsCells
    637. Cash AD, Perry G, Smith MA. Therapeutic potential in Alzheimer disease. Curr Med Chem. 2002 Sep; 9(17):1605-10. PMID: 12171555.
      Citations: 4     Fields:    Translation:HumansAnimals
    638. Tamagno E, Bardini P, Obbili A, Vitali A, Borghi R, Zaccheo D, Pronzato MA, Danni O, Smith MA, Perry G, Tabaton M. Oxidative stress increases expression and activity of BACE in NT2 neurons. Neurobiol Dis. 2002 Aug; 10(3):279-88. PMID: 12270690.
      Citations: 168     Fields:    Translation:HumansCells
    639. Smith MA, Atwood CS, Joseph JA, Perry G. Ill-fated amyloid-beta vaccine. J Neurosci Res. 2002 Aug 01; 69(3):285. PMID: 12125069.
      Citations:    Fields:    Translation:Humans
    640. Shi J, Perry G, Berridge MS, Aliev G, Siedlak SL, Smith MA, LaManna JC, Friedland RP. Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice. J Nucl Med. 2002 Aug; 43(8):1044-51. PMID: 12163630.
      Citations: 9     Fields:    Translation:HumansAnimals
    641. Pappolla MA, Smith MA, Bryant-Thomas T, Bazan N, Petanceska S, Perry G, Thal LJ, Sano M, Refolo LM. Cholesterol, oxidative stress, and Alzheimer's disease: expanding the horizons of pathogenesis. Free Radic Biol Med. 2002 Jul 15; 33(2):173-81. PMID: 12106813.
      Citations: 18     Fields:    Translation:HumansAnimals
    642. Atwood CS, Martins RN, Smith MA, Perry G. Senile plaque composition and posttranslational modification of amyloid-beta peptide and associated proteins. Peptides. 2002 Jul; 23(7):1343-50. PMID: 12128091.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    643. Rottkamp CA, Atwood CS, Joseph JA, Nunomura A, Perry G, Smith MA. The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease. Peptides. 2002 Jul; 23(7):1333-41. PMID: 12128090.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    644. Smith MA, Perry G, Pryor WA. Causes and consequences of oxidative stress in Alzheimer's disease. Free Radic Biol Med. 2002 Jun 01; 32(11):1049. PMID: 12031888.
      Citations: 16     Fields:    Translation:HumansAnimals
    645. Smith MA, Atwood CS, Joseph JA, Perry G. Predicting the failure of amyloid-beta vaccine. Lancet. 2002 May 25; 359(9320):1864-5. PMID: 12044411.
      Citations: 18     Fields:    Translation:HumansAnimals
    646. Smith MA, Joseph JA, Atwood CS, Perry G. Dangers of the amyloid-beta vaccination. Acta Neuropathol. 2002 Jul; 104(1):110. PMID: 12070672.
      Citations: 1     Fields:    Translation:Humans
    647. Reddy VP, Obrenovich ME, Atwood CS, Perry G, Smith MA. Involvement of Maillard reactions in Alzheimer disease. Neurotox Res. 2002 May; 4(3):191-209. PMID: 12829400.
      Citations: 23     Fields:    
    648. Smith MA, Drew KL, Nunomura A, Takeda A, Hirai K, Zhu X, Atwood CS, Raina AK, Rottkamp CA, Sayre LM, Friedland RP, Perry G. Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs? Neurochem Int. 2002 May; 40(6):527-31. PMID: 11850109.
      Citations: 30     Fields:    Translation:HumansCells
    649. Bishop GM, Robinson SR, Smith MA, Perry G, Atwood CS. Call for Elan to publish Alzheimer's trial details. Nature. 2002 Apr 18; 416(6882):677. PMID: 11961526.
      Citations: 5     Fields:    Translation:HumansAnimals
    650. Guentchev M, Siedlak SL, Jarius C, Tagliavini F, Castellani RJ, Perry G, Smith MA, Budka H. Oxidative damage to nucleic acids in human prion disease. Neurobiol Dis. 2002 Apr; 9(3):275-81. PMID: 11950273.
      Citations: 20     Fields:    Translation:Humans
    651. Kakimura J, Kitamura Y, Takata K, Umeki M, Suzuki S, Shibagaki K, Taniguchi T, Nomura Y, Gebicke-Haerter PJ, Smith MA, Perry G, Shimohama S. Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins. FASEB J. 2002 Apr; 16(6):601-3. PMID: 11919167.
      Citations: 120     Fields:    Translation:HumansAnimalsCells
    652. Pappolla MA, Simovich MJ, Bryant-Thomas T, Chyan YJ, Poeggeler B, Dubocovich M, Bick R, Perry G, Cruz-Sanchez F, Smith MA. The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors. J Pineal Res. 2002 Apr; 32(3):135-42. PMID: 12074096.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    653. P?rez M, Hern?ndez F, G?mez-Ramos A, Smith M, Perry G, Avila J. Formation of aberrant phosphotau fibrillar polymers in neural cultured cells. Eur J Biochem. 2002 Mar; 269(5):1484-9. PMID: 11874463.
      Citations: 30     Fields:    Translation:HumansCells
    654. Ogawa O, Perry G, Smith MA. The "Down's" side of mitochondria. Dev Cell. 2002 Mar; 2(3):255-6. PMID: 11879629.
      Citations: 6     Fields:    Translation:HumansCells
    655. Kikuchi A, Takeda A, Onodera H, Kimpara T, Hisanaga K, Sato N, Nunomura A, Castellani RJ, Perry G, Smith MA, Itoyama Y. Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy. Neurobiol Dis. 2002 Mar; 9(2):244-8. PMID: 11895375.
      Citations: 104     Fields:    Translation:HumansCells
    656. Borghi R, Giliberto L, Assini A, Delacourte A, Perry G, Smith MA, Strocchi P, Zaccheo D, Tabaton M. Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy. Neurology. 2002 Feb 26; 58(4):589-92. PMID: 11865137.
      Citations: 8     Fields:    Translation:HumansCells
    657. Castellani RJ, Perry G, Siedlak SL, Nunomura A, Shimohama S, Zhang J, Montine T, Sayre LM, Smith MA. Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans. Neurosci Lett. 2002 Feb 08; 319(1):25-8. PMID: 11814645.
      Citations: 54     Fields:    Translation:HumansCells
    658. Clapp-Lilly KL, Smith MA, Perry G, Harris PL, Zhu X, Drew KL, Duffy LK. Melatonin exhibits antioxidant properties in a mouse brain slice model of excitotoxicity. Int J Circumpolar Health. 2002 Feb; 61(1):32-40. PMID: 12002945.
      Citations: 1     Fields:    Translation:Animals
    659. Aliev G, Smith MA, Seyidov D, Neal ML, Lamb BT, Nunomura A, Gasimov EK, Vinters HV, Perry G, LaManna JC, Friedland RP. The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease. Brain Pathol. 2002 Jan; 12(1):21-35. PMID: 11770899.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    660. Perry G, Cash AD, Smith MA. Alzheimer Disease and Oxidative Stress. J Biomed Biotechnol. 2002; 2(3):120-123. PMID: 12488575.
      Citations: 119     Fields:    
    661. Perry G, Sayre LM, Atwood CS, Castellani RJ, Cash AD, Rottkamp CA, Smith MA. The role of iron and copper in the aetiology of neurodegenerative disorders: therapeutic implications. CNS Drugs. 2002; 16(5):339-52. PMID: 11994023.
      Citations: 26     Fields:    Translation:HumansCells
    662. Bishop GM, Robinson SR, Liu Q, Perry G, Atwood CS, Smith MA. Iron: a pathological mediator of Alzheimer disease? Dev Neurosci. 2002; 24(2-3):184-7. PMID: 12401957.
      Citations: 42     Fields:    Translation:Humans
    663. Perry G, Nunomura A, Cash AD, Taddeo MA, Hirai K, Aliev G, Avila J, Wataya T, Shimohama S, Atwood CS, Smith MA. Reactive oxygen: its sources and significance in Alzheimer disease. J Neural Transm Suppl. 2002; (62):69-75. PMID: 12456052.
      Citations: 10     Fields:    Translation:Humans
    664. Aliev G, Smith MA, Seyidova D, Neal ML, Shi J, Loizidou M, Turmaine M, Friedland RP, Taylor I, Burnstock G, Perry G, Lamanna JC. Increased expression of NOS and ET-1 immunoreactivity in human colorectal metastatic liver tumours is associated with selective depression of constitutive NOS immunoreactivity in vessel endothelium. J Submicrosc Cytol Pathol. 2002 Jan; 34(1):37-50. PMID: 11989855.
      Citations: 5     Fields:    Translation:HumansCells
    665. Zhang J, Montine TJ, Smith MA, Siedlak SL, Gu G, Robertson D, Perry G. The mitochondrial common deletion in Parkinson's disease and related movement disorders. Parkinsonism Relat Disord. 2002 Jan; 8(3):165-70. PMID: 12039426.
      Citations: 9     Fields:    Translation:Humans
    666. Zhou F, Smith MA, Castellani RJ, Stimmelmayr R, Perry G, Drew KL, Zhu X. Hibernation, a Model of Neuroprotection. ScientificWorldJournal. 2001; 1:108. PMID: 30147589.
      Citations: 2     Fields:    
    667. Wataya T, Nunomura A, Smith MA, Siedlak SL, Harris PL, Shimohama S, Szweda LI, Kaminski MA, Avila J, Price DL, Cleveland DW, Sayre LM, Perry G. High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal. J Biol Chem. 2002 Feb 15; 277(7):4644-8. PMID: 11733539.
      Citations: 31     Fields:    Translation:AnimalsCells
    668. Zhu X, Castellani RJ, Takeda A, Nunomura A, Atwood CS, Perry G, Smith MA. Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis. Mech Ageing Dev. 2001 Dec; 123(1):39-46. PMID: 11640950.
      Citations: 112     Fields:    Translation:HumansCells
    669. Bierhaus A, Schiekofer S, Schwaninger M, Andrassy M, Humpert PM, Chen J, Hong M, Luther T, Henle T, Kl?ting I, Morcos M, Hofmann M, Tritschler H, Weigle B, Kasper M, Smith M, Perry G, Schmidt AM, Stern DM, H?ring HU, Schleicher E, Nawroth PP. Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB. Diabetes. 2001 Dec; 50(12):2792-808. PMID: 11723063.
      Citations: 290     Fields:    Translation:HumansAnimalsCells
    670. Zhu X, Rottkamp CA, Hartzler A, Sun Z, Takeda A, Boux H, Shimohama S, Perry G, Smith MA. Activation of MKK6, an upstream activator of p38, in Alzheimer's disease. J Neurochem. 2001 Oct; 79(2):311-8. PMID: 11677259.
      Citations: 53     Fields:    Translation:HumansCells
    671. Nunomura A, Perry G, Aliev G, Hirai K, Takeda A, Balraj EK, Jones PK, Ghanbari H, Wataya T, Shimohama S, Chiba S, Atwood CS, Petersen RB, Smith MA. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol. 2001 Aug; 60(8):759-67. PMID: 11487050.
      Citations: 661     Fields:    Translation:HumansCells
    672. Aliev G, Smith MA, Turmaine M, Neal ML, Zimina TV, Friedland RP, Perry G, LaManna JC, Burnstock G. Atherosclerotic lesions are associated with increased immunoreactivity for inducible nitric oxide synthase and endothelin-1 in thoracic aortic intimal cells of hyperlipidemic Watanabe rabbits. Exp Mol Pathol. 2001 Aug; 71(1):40-54. PMID: 11502096.
      Citations: 8     Fields:    Translation:AnimalsCells
    673. Castellani RJ, Harris PL, Sayre LM, Fujii J, Taniguchi N, Vitek MP, Founds H, Atwood CS, Perry G, Smith MA. Active glycation in neurofibrillary pathology of Alzheimer disease: N(epsilon)-(carboxymethyl) lysine and hexitol-lysine. Free Radic Biol Med. 2001 Jul 15; 31(2):175-80. PMID: 11440829.
      Citations: 57     Fields:    Translation:HumansCells
    674. Pappolla MA, Omar RA, Chyan YJ, Ghiso J, Hsiao K, Bozner P, Perry G, Smith MA, Cruz-Sanchez F. Induction of NADPH cytochrome P450 reductase by the Alzheimer beta-protein. Amyloid as a "foreign body". J Neurochem. 2001 Jul; 78(1):121-8. PMID: 11432979.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    675. Sayre LM, Smith MA, Perry G. Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr Med Chem. 2001 Jun; 8(7):721-38. PMID: 11375746.
      Citations: 164     Fields:    Translation:HumansCells
    676. Zhou F, Zhu X, Castellani RJ, Stimmelmayr R, Perry G, Smith MA, Drew KL. Hibernation, a model of neuroprotection. Am J Pathol. 2001 Jun; 158(6):2145-51. PMID: 11395392.
      Citations: 48     Fields:    Translation:Animals
    677. Campbell A, Smith MA, Sayre LM, Bondy SC, Perry G. Mechanisms by which metals promote events connected to neurodegenerative diseases. Brain Res Bull. 2001 May 15; 55(2):125-32. PMID: 11470308.
      Citations: 21     Fields:    Translation:HumansAnimals
    678. Clapp-Lilly KL, Smith MA, Perry G, Harris PL, Zhu X, Duffy LK. Melatonin acts as antioxidant and pro-oxidant in an organotypic slice culture model of Alzheimer's disease. Neuroreport. 2001 May 08; 12(6):1277-80. PMID: 11338206.
      Citations: 9     Fields:    Translation:AnimalsCells
    679. Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PL, Jones PK, Petersen RB, Perry G, Smith MA. Mitochondrial abnormalities in Alzheimer's disease. J Neurosci. 2001 May 01; 21(9):3017-23. PMID: 11312286.
      Citations: 590     Fields:    Translation:HumansCells
    680. Raina AK, Hochman A, Zhu X, Rottkamp CA, Nunomura A, Siedlak SL, Boux H, Castellani RJ, Perry G, Smith MA. Abortive apoptosis in Alzheimer's disease. Acta Neuropathol. 2001 Apr; 101(4):305-10. PMID: 11355301.
      Citations: 47     Fields:    Translation:HumansCells
    681. Wong BS, Liu T, Paisley D, Li R, Pan T, Chen SG, Perry G, Petersen RB, Smith MA, Melton DW, Gambetti P, Brown DR, Sy MS. Induction of HO-1 and NOS in doppel-expressing mice devoid of PrP: implications for doppel function. Mol Cell Neurosci. 2001 Apr; 17(4):768-75. PMID: 11312611.
      Citations: 17     Fields:    Translation:AnimalsCells
    682. Alicig?zel Y, Ozdem SN, Ozdem SS, Karayal?in U, Siedlak SL, Perry G, Smith MA. Erythrocyte, plasma, and serum antioxidant activities in untreated toxic multinodular goiter patients. Free Radic Biol Med. 2001 Mar 15; 30(6):665-70. PMID: 11295364.
      Citations: 4     Fields:    Translation:HumansCells
    683. Clapp-Lilly KL, Smith MA, Perry G, Duffy LK. Melatonin reduces interleukin secretion in amyloid-beta stressed mouse brain slices. Chem Biol Interact. 2001 Mar 14; 134(1):101-7. PMID: 11248225.
      Citations: 8     Fields:    Translation:Animals
    684. Rottkamp CA, Raina AK, Zhu X, Gaier E, Bush AI, Atwood CS, Chevion M, Perry G, Smith MA. Redox-active iron mediates amyloid-beta toxicity. Free Radic Biol Med. 2001 Feb 15; 30(4):447-50. PMID: 11182300.
      Citations: 123     Fields:    Translation:HumansCells
    685. Perry G, Avila J, Espey MG, Wink DA, Atwood CS, Smith MA. Biochemistry of neurodegeneration. Science. 2001 Jan 26; 291(5504):595-7. PMID: 11229401.
      Citations: 3     Fields:    Translation:HumansCells
    686. Zhu X, Raina AK, Rottkamp CA, Aliev G, Perry G, Boux H, Smith MA. Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease. J Neurochem. 2001 Jan; 76(2):435-41. PMID: 11208906.
      Citations: 155     Fields:    Translation:HumansCells
    687. Perry G, Zhu X, Smith MA. Do neurons have a choice in death? Am J Pathol. 2001 Jan; 158(1):1-2. PMID: 11141471.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    688. Aliev G, Seyidov D, Neal ML, Shi J, Vigan T, Hernandez A, Folco G, Soas AH, Zimina TV, Smith MA, Perry G, Lamanna JC, Friedland RP. The effect of agonists and antagonists on the morphology of non-transformed human smooth muscle cell in vitro. J Submicrosc Cytol Pathol. 2001 Jan-Apr; 33(1-2):141-9. PMID: 11686395.
      Citations: 1     Fields:    Translation:HumansCells
    689. Alicig?zel Y, Ozdem S, Demir AY, Unal F, Kumbul D, Ozdem SS, Perry G, Smith MA. Effect of the herbicide 4-CPA on human erythrocyte antioxidant enzymes in vitro. Redox Rep. 2001; 6(3):153-4. PMID: 11523589.
      Citations:    Fields:    Translation:HumansCells
    690. Wong BS, Liu T, Li R, Pan T, Petersen RB, Smith MA, Gambetti P, Perry G, Manson JC, Brown DR, Sy MS. Increased levels of oxidative stress markers detected in the brains of mice devoid of prion protein. J Neurochem. 2001 Jan; 76(2):565-72. PMID: 11208919.
      Citations: 36     Fields:    Translation:AnimalsCells
    691. Joseph J, Shukitt-Hale B, Denisova NA, Martin A, Perry G, Smith MA. Copernicus revisited: amyloid beta in Alzheimer's disease. Neurobiol Aging. 2001 Jan-Feb; 22(1):131-46. PMID: 11164287.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    692. P?rez M, Cuadros R, Smith MA, Perry G, Avila J. Phosphorylated, but not native, tau protein assembles following reaction with the lipid peroxidation product, 4-hydroxy-2-nonenal. FEBS Lett. 2000 Dec 15; 486(3):270-4. PMID: 11119717.
      Citations: 28     Fields:    Translation:AnimalsCells
    693. Mah AL, Perry G, Smith MA, Monteiro MJ. Identification of ubiquilin, a novel presenilin interactor that increases presenilin protein accumulation. J Cell Biol. 2000 Nov 13; 151(4):847-62. PMID: 11076969.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    694. Nunomura A, Perry G, Pappolla MA, Friedland RP, Hirai K, Chiba S, Smith MA. Neuronal oxidative stress precedes amyloid-beta deposition in Down syndrome. J Neuropathol Exp Neurol. 2000 Nov; 59(11):1011-7. PMID: 11089579.
      Citations: 103     Fields:    Translation:HumansCells
    695. Zhu X, Rottkamp CA, Boux H, Takeda A, Perry G, Smith MA. Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease. J Neuropathol Exp Neurol. 2000 Oct; 59(10):880-8. PMID: 11079778.
      Citations: 124     Fields:    Translation:HumansCells
    696. Takeda A, Smith MA, Avil? J, Nunomura A, Siedlak SL, Zhu X, Perry G, Sayre LM. In Alzheimer's disease, heme oxygenase is coincident with Alz50, an epitope of tau induced by 4-hydroxy-2-nonenal modification. J Neurochem. 2000 Sep; 75(3):1234-41. PMID: 10936206.
      Citations: 55     Fields:    Translation:HumansCells
    697. Aliev G, Shi J, Perry G, Friedland RP, Lamanna JC. Decreased constitutive nitric oxide synthase, but increased inducible nitric oxide synthase and endothelin-1 immunoreactivity in aortic endothelial cells of donryu rats on a cholesterol-enriched diet. Anat Rec. 2000 09 01; 260(1):16-25. PMID: 10967532.
      Citations: 5     Fields:    Translation:Animals
    698. Castellani RJ, Siedlak SL, Perry G, Smith MA. Sequestration of iron by Lewy bodies in Parkinson's disease. Acta Neuropathol. 2000 Aug; 100(2):111-4. PMID: 10963356.
      Citations: 94     Fields:    Translation:HumansCells
    699. Rottkamp CA, Nunomura A, Hirai K, Sayre LM, Perry G, Smith MA. Will antioxidants fulfill their expectations for the treatment of Alzheimer disease? Mech Ageing Dev. 2000 Jul 31; 116(2-3):169-79. PMID: 10996017.
      Citations: 4     Fields:    Translation:HumansCells
    700. Smith MA, Rottkamp CA, Nunomura A, Raina AK, Perry G. Oxidative stress in Alzheimer's disease. Biochim Biophys Acta. 2000 Jul 26; 1502(1):139-44. PMID: 10899439.
      Citations: 195     Fields:    Translation:HumansCells
    701. Perry G, Nunomura A, Hirai K, Takeda A, Aliev G, Smith MA. Oxidative damage in Alzheimer's disease: the metabolic dimension. Int J Dev Neurosci. 2000 Jul-Aug; 18(4-5):417-21. PMID: 10817925.
      Citations: 35     Fields:    Translation:HumansCells
    702. Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI. Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc. J Biol Chem. 2000 Jun 30; 275(26):19439-42. PMID: 10801774.
      Citations: 103     Fields:    Translation:HumansAnimalsCells
    703. Shimohama S, Tanino H, Kawakami N, Okamura N, Kodama H, Yamaguchi T, Hayakawa T, Nunomura A, Chiba S, Perry G, Smith MA, Fujimoto S. Activation of NADPH oxidase in Alzheimer's disease brains. Biochem Biophys Res Commun. 2000 Jun 24; 273(1):5-9. PMID: 10873554.
      Citations: 124     Fields:    Translation:HumansAnimalsCells
    704. Sayre LM, Perry G, Atwood CS, Smith MA. The role of metals in neurodegenerative diseases. Cell Mol Biol (Noisy-le-grand). 2000 Jun; 46(4):731-41. PMID: 10875436.
      Citations: 22     Fields:    Translation:HumansCells
    705. Odetti P, Garibaldi S, Norese R, Angelini G, Marinelli L, Valentini S, Menini S, Traverso N, Zaccheo D, Siedlak S, Perry G, Smith MA, Tabaton M. Lipoperoxidation is selectively involved in progressive supranuclear palsy. J Neuropathol Exp Neurol. 2000 May; 59(5):393-7. PMID: 10888369.
      Citations: 24     Fields:    Translation:Humans
    706. Perry G. Medicinal chemistry of neurodegenerative diseases--fourth international symposium. 30 January-2 February 2000, Cancun, Mexico. IDrugs. 2000 May; 3(5):485-9. PMID: 16100677.
      Citations:    Fields:    
    707. Perry G, Smith MA. Promises and pitfalls of therapeutics to modify oxidant balance in chronic disease. IDrugs. 2000 Apr; 3(4):371-2. PMID: 16100688.
      Citations:    Fields:    
    708. Friedland RP, Shi J, Lamanna JC, Smith MA, Perry G. Prospects for noninvasive imaging of brain amyloid beta in Alzheimer's disease. Ann N Y Acad Sci. 2000 Apr; 903:123-8. PMID: 10818497.
      Citations: 2     Fields:    Translation:HumansAnimals
    709. Shi J, Perry G, Smith MA, Friedland RP. Vascular abnormalities: the insidious pathogenesis of Alzheimer's disease. Neurobiol Aging. 2000 Mar-Apr; 21(2):357-61. PMID: 10867221.
      Citations: 27     Fields:    Translation:Humans
    710. Perry G, Raina AK, Nunomura A, Wataya T, Sayre LM, Smith MA. How important is oxidative damage? Lessons from Alzheimer's disease. Free Radic Biol Med. 2000 Mar 01; 28(5):831-4. PMID: 10754280.
      Citations: 48     Fields:    Translation:HumansCells
    711. Perry G, Nunomura A, Raina AK, Smith MA. Amyloid-beta junkies. Lancet. 2000 Feb 26; 355(9205):757. PMID: 10703837.
      Citations: 22     Fields:    Translation:Humans
    712. Takeda A, Perry G, Abraham NG, Dwyer BE, Kutty RK, Laitinen JT, Petersen RB, Smith MA. Overexpression of heme oxygenase in neuronal cells, the possible interaction with Tau. J Biol Chem. 2000 Feb 25; 275(8):5395-9. PMID: 10681514.
      Citations: 37     Fields:    Translation:HumansCells
    713. Raina AK, Perry G, Nunomura A, Sayre LM, Smith MA. Histochemical and immunocytochemical approaches to the study of oxidative stress. Clin Chem Lab Med. 2000 Feb; 38(2):93-7. PMID: 10834395.
      Citations: 1     Fields:    Translation:HumansCells
    714. Rottkamp CA, Nunomura A, Raina AK, Sayre LM, Perry G, Smith MA. Oxidative stress, antioxidants, and Alzheimer disease. Alzheimer Dis Assoc Disord. 2000; 14 Suppl 1:S62-6. PMID: 10850732.
      Citations: 19     Fields:    Translation:HumansCells
    715. Sayre LM, Perry G, Harris PL, Liu Y, Schubert KA, Smith MA. In situ oxidative catalysis by neurofibrillary tangles and senile plaques in Alzheimer's disease: a central role for bound transition metals. J Neurochem. 2000 Jan; 74(1):270-9. PMID: 10617129.
      Citations: 163     Fields:    Translation:HumansCells
    716. Castellani RJ, Harris PL, Lecroisey A, Izadi-Pruneyre N, Wandersman C, Perry G, Smith MA. Evidence for a novel heme-binding protein, HasAh, in Alzheimer disease. Antioxid Redox Signal. 2000; 2(1):137-42. PMID: 11232594.
      Citations: 3     Fields:    Translation:HumansCells
    717. Smith MA, Nunomura A, Zhu X, Takeda A, Perry G. Metabolic, metallic, and mitotic sources of oxidative stress in Alzheimer disease. Antioxid Redox Signal. 2000; 2(3):413-20. PMID: 11229355.
      Citations: 48     Fields:    Translation:HumansCells
    718. Kim HT, Russell RL, Raina AK, Harris PL, Siedlak SL, Zhu X, Petersen RB, Shimohama S, Smith MA, Perry G. Protein disulfide isomerase in Alzheimer disease. Antioxid Redox Signal. 2000; 2(3):485-9. PMID: 11229362.
      Citations: 10     Fields:    Translation:HumansCells
    719. Smith MA, Joseph JA, Perry G. Arson. Tracking the culprit in Alzheimer's disease. Ann N Y Acad Sci. 2000; 924:35-8. PMID: 11193799.
      Citations: 15     Fields:    Translation:Humans
    720. Capellari S, Zaidi SI, Urig CB, Perry G, Smith MA, Petersen RB. Prion protein glycosylation is sensitive to redox change. J Biol Chem. 1999 Dec 03; 274(49):34846-50. PMID: 10574957.
      Citations: 19     Fields:    Translation:HumansCells
    721. Smith MA, Petot GJ, Perry G. Diet and oxidative stress: a novel synthesis of epidemiological data on Alzheimer's disease. J Alzheimers Dis. 1999 Nov; 1(4-5):203-6. PMID: 12214119.
      Citations: 24     Fields:    
    722. Shi J, Perry G, Aliev G, Smith MA, Ashe KH, Friedland RP. Serum amyloid P is not present in amyloid beta deposits of a transgenic animal model. Neuroreport. 1999 Oct 19; 10(15):3229-32. PMID: 10574565.
      Citations: 7     Fields:    Translation:Animals
    723. Russell RL, Siedlak SL, Raina AK, Bautista JM, Smith MA, Perry G. Increased neuronal glucose-6-phosphate dehydrogenase and sulfhydryl levels indicate reductive compensation to oxidative stress in Alzheimer disease. Arch Biochem Biophys. 1999 Oct 15; 370(2):236-9. PMID: 10510282.
      Citations: 37     Fields:    Translation:HumansCells
    724. Aliev G, Ragazzi E, Smith MA, Mironov A, Perry G. Morphological features of regeneration of rabbit aortic endothelium after cryoinduced vascular damage. J Submicrosc Cytol Pathol. 1999 Oct; 31(4):495-502. PMID: 10685390.
      Citations: 2     Fields:    Translation:AnimalsCells
    725. Castellani RJ, Perry G, Brenner DS, Smith MA. Alexander disease: Alzheimer disease of the developing brain? Alzheimer Dis Assoc Disord. 1999 Oct-Dec; 13(4):232-5. PMID: 10609673.
      Citations: 4     Fields:    Translation:HumansCells
    726. Perry G. Neuronal apoptosis--ISN satellite symposium. 5-7 August 1999, T?bingen, Germany. IDrugs. 1999 Oct; 2(10):992-4. PMID: 16118705.
      Citations:    Fields:    
    727. Perry G, Roder H, Nunomura A, Takeda A, Friedlich AL, Zhu X, Raina AK, Holbrook N, Siedlak SL, Harris PL, Smith MA. Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation. Neuroreport. 1999 Aug 02; 10(11):2411-5. PMID: 10439473.
      Citations: 96     Fields:    Translation:HumansCells
    728. Smith MA, Nunomura A, Takeda A, Perry G. Asking the right questions. Science. 1999 Jul 30; 285(5428):665. PMID: 10454920.
      Citations:    Fields:    Translation:Humans
    729. Castellani RJ, Smith MA, Nunomura A, Harris PL, Perry G. Is increased redox-active iron in Alzheimer disease a failure of the copper-binding protein ceruloplasmin? Free Radic Biol Med. 1999 Jun; 26(11-12):1508-12. PMID: 10401616.
      Citations: 19     Fields:    Translation:HumansCells
    730. Zhang J, Perry G, Smith MA, Robertson D, Olson SJ, Graham DG, Montine TJ. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol. 1999 May; 154(5):1423-9. PMID: 10329595.
      Citations: 204     Fields:    Translation:HumansCellsCTClinical Trials
    731. Raina AK, Takeda A, Nunomura A, Perry G, Smith MA. Genetic evidence for oxidative stress in Alzheimer's disease. Neuroreport. 1999 Apr 26; 10(6):1355-7. PMID: 10363952.
      Citations: 4     Fields:    Translation:Humans
    732. Sayre LM, Perry G, Smith MA. Redox metals and neurodegenerative disease. Curr Opin Chem Biol. 1999 Apr; 3(2):220-5. PMID: 10226049.
      Citations: 38     Fields:    Translation:HumansCells
    733. Nunomura A, Perry G, Pappolla MA, Wade R, Hirai K, Chiba S, Smith MA. RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease. J Neurosci. 1999 Mar 15; 19(6):1959-64. PMID: 10066249.
      Citations: 258     Fields:    Translation:HumansCells
    734. Morgan TE, Xie Z, Goldsmith S, Yoshida T, Lanzrein AS, Stone D, Rozovsky I, Perry G, Smith MA, Finch CE. The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction. Neuroscience. 1999 Mar; 89(3):687-99. PMID: 10199605.
      Citations: 54     Fields:    Translation:AnimalsCells
    735. Perry G, Smith MA. [Is the lesion produced by oxidation a central part in the pathogenesis of Alzheimer's disease?]. Neurologia. 1999 Feb; 14(2):78-84. PMID: 10100423.
      Citations:    Fields:    Translation:Humans
    736. Raina AK, Templeton DJ, Deak JC, Perry G, Smith MA. Quinone reductase (NQO1), a sensitive redox indicator, is increased in Alzheimer's disease. Redox Rep. 1999; 4(1-2):23-7. PMID: 10714272.
      Citations: 50     Fields:    Translation:Humans
    737. Sayre LM, Perry G, Smith MA. In situ methods for detection and localization of markers of oxidative stress: application in neurodegenerative disorders. Methods Enzymol. 1999; 309:133-52. PMID: 10507022.
      Citations: 7     Fields:    Translation:HumansCells
    738. Nunomura A, Perry G, Hirai K, Aliev G, Takeda A, Chiba S, Smith MA. Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome. Ann N Y Acad Sci. 1999; 893:362-4. PMID: 10672267.
      Citations: 35     Fields:    Translation:HumansCells
    739. Gerst JL, Siedlak SL, Nunomura A, Castellani R, Perry G, Smith MA. Role of oxidative stress in frontotemporal dementia. Dement Geriatr Cogn Disord. 1999; 10 Suppl 1:85-7. PMID: 10436348.
      Citations: 5     Fields:    Translation:Humans
    740. Chen X, Eswaran D, Smith MA, Perry G, Anderson VE. Universal isolation of cross-linked peptides: application to neurofibrillary tangles. Bioconjug Chem. 1999 Jan-Feb; 10(1):112-8. PMID: 9893972.
      Citations: 2     Fields:    Translation:HumansCells
    741. Velasco ME, Smith MA, Siedlak SL, Nunomura A, Perry G. Striation is the characteristic neuritic abnormality in Alzheimer disease. Brain Res. 1998 Dec 07; 813(2):329-33. PMID: 9838181.
      Citations: 14     Fields:    Translation:HumansCells
    742. Smith MA, Perry G. What are the facts and artifacts of the pathogenesis and etiology of Alzheimer disease? J Chem Neuroanat. 1998 Dec; 16(1):35-41. PMID: 9924971.
      Citations: 3     Fields:    Translation:Humans
    743. Smith MA, Vas?k M, Knipp M, Castellani RJ, Perry G. Dimethylargininase, a nitric oxide regulatory protein, in Alzheimer disease. Free Radic Biol Med. 1998 Nov 15; 25(8):898-902. PMID: 9840734.
      Citations: 6     Fields:    Translation:HumansCells
    744. Perry G, Nunomura A, Lucassen P, Lassmann H, Smith MA. Apoptosis and Alzheimer's disease. Science. 1998 Nov 13; 282(5392):1268-9. PMID: 9867630.
      Citations: 20     Fields:    Translation:HumansCells
    745. Hattori N, Kitagawa K, Higashida T, Yagyu K, Shimohama S, Wataya T, Perry G, Smith MA, Inagaki C. CI-ATPase and Na+/K(+)-ATPase activities in Alzheimer's disease brains. Neurosci Lett. 1998 Oct 02; 254(3):141-4. PMID: 10214977.
      Citations: 49     Fields:    Translation:HumansCells
    746. Guevara J, Espinosa B, Zenteno E, V?zguez L, Luna J, Perry G, Mena R. Altered glycosylation pattern of proteins in Alzheimer disease. J Neuropathol Exp Neurol. 1998 Oct; 57(10):905-14. PMID: 9786241.
      Citations: 11     Fields:    Translation:HumansCells
    747. Perry G, Nunomura A, Smith MA. A suicide note from Alzheimer disease neurons? Nat Med. 1998 Aug; 4(8):897-8. PMID: 9701239.
      Citations: 10     Fields:    Translation:HumansCells
    748. Perry G, Smith MA. Is oxidative damage central to the pathogenesis of Alzheimer disease? Acta Neurol Belg. 1998 Jun; 98(2):175-9. PMID: 9686276.
      Citations: 4     Fields:    Translation:HumansCells
    749. Smith MA, Sayre LM, Anderson VE, Harris PL, Beal MF, Kowall N, Perry G. Cytochemical demonstration of oxidative damage in Alzheimer disease by immunochemical enhancement of the carbonyl reaction with 2,4-dinitrophenylhydrazine. J Histochem Cytochem. 1998 Jun; 46(6):731-5. PMID: 9603784.
      Citations: 57     Fields:    Translation:HumansCells
    750. Smith MA, Hirai K, Hsiao K, Pappolla MA, Harris PL, Siedlak SL, Tabaton M, Perry G. Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress. J Neurochem. 1998 May; 70(5):2212-5. PMID: 9572310.
      Citations: 138     Fields:    Translation:Animals
    751. Perry G, Smith MA, McCann CE, Siedlak SL, Jones PK, Friedland RP. Cerebrovascular muscle atrophy is a feature of Alzheimer's disease. Brain Res. 1998 Apr 27; 791(1-2):63-6. PMID: 9593825.
      Citations: 18     Fields:    Translation:Humans
    752. Pappolla MA, Chyan YJ, Omar RA, Hsiao K, Perry G, Smith MA, Bozner P. Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo. Am J Pathol. 1998 Apr; 152(4):871-7. PMID: 9546346.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    753. Smith MA, Wehr K, Harris PL, Siedlak SL, Connor JR, Perry G. Abnormal localization of iron regulatory protein in Alzheimer's disease. Brain Res. 1998 Mar 30; 788(1-2):232-6. PMID: 9555030.
      Citations: 45     Fields:    Translation:HumansCells
    754. Castellani RJ, Perry G, Harris PL, Cohen ML, Sayre LM, Salomon RG, Smith MA. Advanced lipid peroxidation end-products in Alexander's disease. Brain Res. 1998 Mar 16; 787(1):15-8. PMID: 9518535.
      Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
    755. Perry G, Castellani RJ, Hirai K, Smith MA. Reactive Oxygen Species Mediate Cellular Damage in Alzheimer Disease. J Alzheimers Dis. 1998 Mar; 1(1):45-55. PMID: 12214011.
      Citations: 55     Fields:    
    756. Odetti P, Angelini G, Dapino D, Zaccheo D, Garibaldi S, Dagna-Bricarelli F, Piombo G, Perry G, Smith M, Traverso N, Tabaton M. Early glycoxidation damage in brains from Down's syndrome. Biochem Biophys Res Commun. 1998 Feb 24; 243(3):849-51. PMID: 9501012.
      Citations: 30     Fields:    Translation:HumansCells
    757. DeWitt DA, Perry G, Cohen M, Doller C, Silver J. Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease. Exp Neurol. 1998 Feb; 149(2):329-40. PMID: 9500964.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    758. Kitamura Y, Shimohama S, Kamoshima W, Ota T, Matsuoka Y, Nomura Y, Smith MA, Perry G, Whitehouse PJ, Taniguchi T. Alteration of proteins regulating apoptosis, Bcl-2, Bcl-x, Bax, Bak, Bad, ICH-1 and CPP32, in Alzheimer's disease. Brain Res. 1998 Jan 12; 780(2):260-9. PMID: 9507158.
      Citations: 65     Fields:    Translation:HumansCells
    759. M?nch G, Schinzel R, Loske C, Wong A, Durany N, Li JJ, Vlassara H, Smith MA, Perry G, Riederer P. Alzheimer's disease--synergistic effects of glucose deficit, oxidative stress and advanced glycation endproducts. J Neural Transm (Vienna). 1998; 105(4-5):439-61. PMID: 9720973.
      Citations: 69     Fields:    Translation:Humans
    760. Smith MA, Harris PL, Sayre LM, Perry G. Iron accumulation in Alzheimer disease is a source of redox-generated free radicals. Proc Natl Acad Sci U S A. 1997 Sep 02; 94(18):9866-8. PMID: 9275217.
      Citations: 408     Fields:    Translation:HumansCells
    761. Castellani RJ, Perry G, Harris PL, Monnier VM, Cohen ML, Smith MA. Advanced glycation modification of Rosenthal fibers in patients with Alexander disease. Neurosci Lett. 1997 Aug 08; 231(2):79-82. PMID: 9291145.
      Citations: 2     Fields:    Translation:HumansCells
    762. Smith MA, Nagaraj RH, Perry G. Protocol for quantitative analysis of paired helical filament solubilization: a method applicable to insoluble amyloids and inclusion bodies. Brain Res Brain Res Protoc. 1997 Aug; 1(3):247-52. PMID: 9385061.
      Citations: 1     Fields:    Translation:HumansCells
    763. Sayre LM, Zelasko DA, Harris PL, Perry G, Salomon RG, Smith MA. 4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease. J Neurochem. 1997 May; 68(5):2092-7. PMID: 9109537.
      Citations: 277     Fields:    Translation:HumansCells
    764. Sayre LM, Zagorski MG, Surewicz WK, Krafft GA, Perry G. Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal. Chem Res Toxicol. 1997 May; 10(5):518-26. PMID: 9168248.
      Citations: 14     Fields:    Translation:HumansAnimals
    765. Salomon RG, Subbanagounder G, O'Neil J, Kaur K, Smith MA, Hoff HF, Perry G, Monnier VM. Levuglandin E2-protein adducts in human plasma and vasculature. Chem Res Toxicol. 1997 May; 10(5):536-45. PMID: 9168251.
      Citations: 21     Fields:    Translation:HumansAnimals
    766. Smith MA, Richey Harris PL, Sayre LM, Beckman JS, Perry G. Widespread peroxynitrite-mediated damage in Alzheimer's disease. J Neurosci. 1997 Apr 15; 17(8):2653-7. PMID: 9092586.
      Citations: 297     Fields:    Translation:HumansCells
    767. Tabaton M, Perry G, Smith M, Vitek M, Angelini G, Dapino D, Garibaldi S, Zaccheo D, Odetti P. Is amyloid beta-protein glycated in Alzheimer's disease? Neuroreport. 1997 Mar 03; 8(4):907-9. PMID: 9141062.
      Citations: 9     Fields:    Translation:HumansCells
    768. Smith MA, Perry G. The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis. J Neuropathol Exp Neurol. 1997 Feb; 56(2):217. PMID: 9034378.
      Citations: 4     Fields:    Translation:Humans
    769. Castellani R, Smith MA, Richey PL, Perry G. Glycoxidation and oxidative stress in Parkinson disease and diffuse Lewy body disease. Brain Res. 1996 Oct 21; 737(1-2):195-200. PMID: 8930366.
      Citations: 92     Fields:    Translation:HumansCells
    770. Smith MA, Tabaton M, Perry G. Early contribution of oxidative glycation in Alzheimer disease. Neurosci Lett. 1996 Oct 18; 217(2-3):210-1. PMID: 8916111.
      Citations: 6     Fields:    Translation:HumansCells
    771. Xiao J, Perry G, Troncoso J, Monteiro MJ. alpha-calcium-calmodulin-dependent kinase II is associated with paired helical filaments of Alzheimer's disease. J Neuropathol Exp Neurol. 1996 Sep; 55(9):954-63. PMID: 8800091.
      Citations: 20     Fields:    Translation:HumansCells
    772. Smith MA, Perry G, Richey PL, Sayre LM, Anderson VE, Beal MF, Kowall N. Oxidative damage in Alzheimer's. Nature. 1996 Jul 11; 382(6587):120-1. PMID: 8700201.
      Citations: 208     Fields:    Translation:HumansCells
    773. Smith MA, Sayre LM, Monnier VM, Perry G. Oxidative posttranslational modifications in Alzheimer disease. A possible pathogenic role in the formation of senile plaques and neurofibrillary tangles. Mol Chem Neuropathol. 1996 May-Aug; 28(1-3):41-8. PMID: 8871940.
      Citations: 16     Fields:    Translation:HumansCells
    774. Smith MA, Siedlak SL, Richey PL, Nagaraj RH, Elhammer A, Perry G. Quantitative solubilization and analysis of insoluble paired helical filaments from Alzheimer disease. Brain Res. 1996 Apr 22; 717(1-2):99-108. PMID: 8738259.
      Citations: 9     Fields:    Translation:HumansCells
    775. Ali SM, Siedlak SL, Gonzalez-DeWhitt PA, Altman RA, Glendening JM, Lowery DE, Savage MJ, Polites HG, Perry G, Greenberg BD. Artifactual strain-specific signs of incipient brain amyloidosis in APP transgenic mice. Neurobiol Aging. 1996 Mar-Apr; 17(2):223-34. PMID: 8744403.
      Citations:    Fields:    Translation:HumansAnimalsCells
    776. Greenberg BD, Savage MJ, Howland DS, Ali SM, Siedlak SL, Perry G, Siman R, Scott RW. APP transgenesis: approaches toward the development of animal models for Alzheimer disease neuropathology. Neurobiol Aging. 1996 Mar-Apr; 17(2):153-71. PMID: 8744397.
      Citations: 7     Fields:    Translation:HumansAnimals
    777. Smith MA, Dunbar CE, Miller EJ, Perry G. Trypsin interaction with the senile plaques of Alzheimer disease is mediated by beta-protein precursor. Mol Chem Neuropathol. 1996 Feb; 27(2):145-54. PMID: 8962599.
      Citations: 1     Fields:    Translation:HumansCells
    778. Smith MA, Sayre LM, Perry G. Diabetes mellitus and Alzheimer's disease: glycation as a biochemical link. Diabetologia. 1996 Feb; 39(2):247. PMID: 8635681.
      Citations: 11     Fields:    Translation:HumansCells
    779. Praprotnik D, Smith MA, Richey PL, Vinters HV, Perry G. Filament heterogeneity within the dystrophic neurites of senile plaques suggests blockage of fast axonal transport in Alzheimer's disease. Acta Neuropathol. 1996; 91(3):226-35. PMID: 8834534.
      Citations: 28     Fields:    Translation:HumansCells
    780. Smith MA, Perry G. Alzheimer disease: protein-protein interaction and oxidative stress. Bol Estud Med Biol. 1996 Jan-Dec; 44(1-4):5-10. PMID: 9369031.
      Citations: 4     Fields:    Translation:HumansCells
    781. Giaccone G, Pedrotti B, Migheli A, Verga L, Perez J, Racagni G, Smith MA, Perry G, De Gioia L, Selvaggini C, Salmona M, Ghiso J, Frangione B, Islam K, Bugiani O, Tagliavini F. beta PP and Tau interaction. A possible link between amyloid and neurofibrillary tangles in Alzheimer's disease. Am J Pathol. 1996 Jan; 148(1):79-87. PMID: 8546229.
      Citations: 16     Fields:    Translation:HumansCells
    782. Praprotnik D, Smith MA, Richey PL, Vinters HV, Perry G. Plasma membrane fragility in dystrophic neurites in senile plaques of Alzheimer's disease: an index of oxidative stress. Acta Neuropathol. 1996; 91(1):1-5. PMID: 8773139.
      Citations: 9     Fields:    Translation:HumansCells
    783. Smith MA, Richey PL, Kalaria RN, Perry G. Elastase is associated with the neurofibrillary pathology of Alzheimer disease: a putative link between proteolytic imbalance and oxidative stress. Restor Neurol Neurosci. 1996 Jan 01; 9(4):213-7. PMID: 21551909.
      Citations:    Fields:    
    784. Smith MA, Perry G. Free radical damage, iron, and Alzheimer's disease. J Neurol Sci. 1995 Dec; 134 Suppl:92-4. PMID: 8847550.
      Citations: 26     Fields:    Translation:Humans
    785. Shimohama S, Fujimoto S, Chachin M, Taniguchi T, Perry G, Whitehouse PJ, Kimura J. Alterations of low molecular weight acid phosphatase protein level in Alzheimer's disease. Brain Res. 1995 Nov 13; 699(1):125-9. PMID: 8616601.
      Citations: 2     Fields:    Translation:Humans
    786. Castellani R, Smith MA, Richey PL, Kalaria R, Gambetti P, Perry G. Evidence for oxidative stress in Pick disease and corticobasal degeneration. Brain Res. 1995 Oct 23; 696(1-2):268-71. PMID: 8574681.
      Citations: 24     Fields:    Translation:HumansCells
    787. Kindy MS, King AR, Perry G, de Beer MC, de Beer FC. Association of apolipoprotein E with murine amyloid A protein amyloid. Lab Invest. 1995 Oct; 73(4):469-75. PMID: 7474917.
      Citations: 10     Fields:    Translation:Animals
    788. Premkumar DR, Smith MA, Richey PL, Petersen RB, Castellani R, Kutty RK, Wiggert B, Perry G, Kalaria RN. Induction of heme oxygenase-1 mRNA and protein in neocortex and cerebral vessels in Alzheimer's disease. J Neurochem. 1995 Sep; 65(3):1399-402. PMID: 7543935.
      Citations: 41     Fields:    Translation:HumansCells
    789. Tabaton M, Rolleri M, Masturzo P, Cammarata S, Angelini G, Hansen LA, Saitoh T, Petersen RB, Perry G, Richey P, et al. Apolipoprotein E epsilon 4 allele frequency is not increased in progressive supranuclear palsy. Neurology. 1995 Sep; 45(9):1764-5. PMID: 7675243.
      Citations: 8     Fields:    Translation:HumansCells
    790. Smith MA, Monnier VM, Sayre LM, Perry G. Amyloidosis, advanced glycation end products and Alzheimer disease. Neuroreport. 1995 Aug 21; 6(12):1595-6. PMID: 8527721.
      Citations: 6     Fields:    Translation:Humans
    791. Yan SD, Yan SF, Chen X, Fu J, Chen M, Kuppusamy P, Smith MA, Perry G, Godman GC, Nawroth P, et al. Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide. Nat Med. 1995 Jul; 1(7):693-9. PMID: 7585153.
      Citations: 113     Fields:    Translation:HumansAnimalsCells
    792. Rifenburg RP, Perry G. Dystrophic neurites define diffuse as well as core-containing senile plaques in Alzheimer's disease. Neurodegeneration. 1995 Jun; 4(2):235-7. PMID: 7583689.
      Citations: 5     Fields:    Translation:HumansCells
    793. Shimohama S, Fujimoto S, Matsushima H, Takenawa T, Taniguchi T, Perry G, Whitehouse PJ, Kimura J. Alteration of phospholipase C-delta protein level and specific activity in Alzheimer's disease. J Neurochem. 1995 Jun; 64(6):2629-34. PMID: 7760043.
      Citations: 4     Fields:    Translation:HumansAnimals
    794. Smith MA, Rudnicka-Nawrot M, Richey PL, Praprotnik D, Mulvihill P, Miller CA, Sayre LM, Perry G. Carbonyl-related posttranslational modification of neurofilament protein in the neurofibrillary pathology of Alzheimer's disease. J Neurochem. 1995 Jun; 64(6):2660-6. PMID: 7539057.
      Citations: 55     Fields:    Translation:HumansCells
    795. Smith MA, Sayre LM, Monnier VM, Perry G. Radical AGEing in Alzheimer's disease. Trends Neurosci. 1995 Apr; 18(4):172-6. PMID: 7778188.
      Citations: 82     Fields:    Translation:HumansCells
    796. Smith MA, Sayre LM, Vitek MP, Monnier VM, Perry G. Early AGEing and Alzheimer's. Nature. 1995 Mar 23; 374(6520):316. PMID: 7885469.
      Citations: 10     Fields:    Translation:Cells
    797. Richey PL, Siedlak SL, Smith MA, Perry G. Apolipoprotein E interaction with the neurofibrillary tangles and senile plaques in Alzheimer disease: implications for disease pathogenesis. Biochem Biophys Res Commun. 1995 Mar 17; 208(2):657-63. PMID: 7695621.
      Citations: 23     Fields:    Translation:HumansCells
    798. Smith MA, Richey PL, Kutty RK, Wiggert B, Perry G. Ultrastructural localization of heme oxygenase-1 to the neurofibrillary pathology of Alzheimer disease. Mol Chem Neuropathol. 1995 Feb-Apr; 24(2-3):227-30. PMID: 7632324.
      Citations: 1     Fields:    Translation:HumansCells
    799. Shimohama S, Perry G, Richey P, Praprotnik D, Takenawa T, Fukami K, Whitehouse PJ, Kimura J. Characterization of the association of phospholipase C-delta with Alzheimer neurofibrillary tangles. Brain Res. 1995 Jan 16; 669(2):217-24. PMID: 7712177.
      Citations: 2     Fields:    Translation:HumansCells
    800. Cras P, Smith MA, Richey PL, Siedlak SL, Mulvihill P, Perry G. Extracellular neurofibrillary tangles reflect neuronal loss and provide further evidence of extensive protein cross-linking in Alzheimer disease. Acta Neuropathol. 1995; 89(4):291-5. PMID: 7610759.
      Citations: 31     Fields:    Translation:HumansCells
    801. Gambetti P, Perry G. Alzheimer's disease and prion proteins: a meeting made in muscle. Am J Pathol. 1994 Dec; 145(6):1261-4. PMID: 7992830.
      Citations: 2     Fields:    Translation:Humans
    802. Smith MA, Richey PL, Taneda S, Kutty RK, Sayre LM, Monnier VM, Perry G. Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease. Ann N Y Acad Sci. 1994 Nov 17; 738:447-54. PMID: 7832455.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    803. DeWitt DA, Richey PL, Praprotnik D, Silver J, Perry G. Chondroitin sulfate proteoglycans are a common component of neuronal inclusions and astrocytic reaction in neurodegenerative diseases. Brain Res. 1994 Sep 05; 656(1):205-9. PMID: 7804839.
      Citations: 17     Fields:    Translation:HumansCells
    804. Smith MA, Kutty RK, Richey PL, Yan SD, Stern D, Chader GJ, Wiggert B, Petersen RB, Perry G. Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease. Am J Pathol. 1994 Jul; 145(1):42-7. PMID: 8030754.
      Citations: 86     Fields:    Translation:HumansCells
    805. Smith MA, Taneda S, Richey PL, Miyata S, Yan SD, Stern D, Sayre LM, Monnier VM, Perry G. Advanced Maillard reaction end products are associated with Alzheimer disease pathology. Proc Natl Acad Sci U S A. 1994 Jun 07; 91(12):5710-4. PMID: 8202552.
      Citations: 151     Fields:    Translation:HumansCells
    806. Smith MA, Perry G. Alzheimer disease: an imbalance of proteolytic regulation? Med Hypotheses. 1994 Apr; 42(4):277-9. PMID: 8072436.
      Citations: 5     Fields:    Translation:HumansCells
    807. Kalaria RN, Perry G. Amyloid P component and other acute-phase proteins associated with cerebellar A beta-deposits in Alzheimer's disease. Brain Res. 1993 Dec 17; 631(1):151-5. PMID: 7507788.
      Citations: 6     Fields:    Translation:Humans
    808. Perry G, Richey PL, Siedlak SL, Smith MA, Mulvihill P, DeWitt DA, Barnett J, Greenberg BD, Kalaria RN. Immunocytochemical evidence that the beta-protein precursor is an integral component of neurofibrillary tangles of Alzheimer's disease. Am J Pathol. 1993 Dec; 143(6):1586-93. PMID: 7504885.
      Citations: 12     Fields:    Translation:HumansCells
    809. Canning DR, McKeon RJ, DeWitt DA, Perry G, Wujek JR, Frederickson RC, Silver J. beta-Amyloid of Alzheimer's disease induces reactive gliosis that inhibits axonal outgrowth. Exp Neurol. 1993 Dec; 124(2):289-98. PMID: 8287928.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    810. Holash JA, Harik SI, Perry G, Stewart PA. Barrier properties of testis microvessels. Proc Natl Acad Sci U S A. 1993 Dec 01; 90(23):11069-73. PMID: 7902579.
      Citations: 20     Fields:    Translation:Animals
    811. Shimohama S, Perry G, Richey P, Takenawa T, Whitehouse PJ, Miyoshi K, Suenaga T, Matsumoto S, Nishimura M, Kimura J. Abnormal accumulation of phospholipase C-delta in filamentous inclusions of human neurodegenerative diseases. Neurosci Lett. 1993 Nov 12; 162(1-2):183-6. PMID: 8121625.
      Citations: 8     Fields:    Translation:HumansCells
    812. Talmadge JE, Jackson JD, Kelsey L, Borgeson CD, Faltynek C, Perry GA. T-cell reconstitution by molecular, phenotypic, and functional analysis in the thymus, bone marrow, spleen, and blood following split-dose polychemotherapy and therapeutic activity for metastatic breast cancer in mice. J Immunother Emphasis Tumor Immunol. 1993 Nov; 14(4):258-68. PMID: 7506577.
      Citations: 4     Fields:    Translation:AnimalsCells
    813. Shimohama S, Fujimoto S, Tresser N, Richey P, Perry G, Whitehouse PJ, Homma Y, Takenawa T, Taniguchi T, Suenaga T, et al. Aberrant phosphoinositide metabolism in Alzheimer's disease. Ann N Y Acad Sci. 1993 Sep 24; 695:46-9. PMID: 8239311.
      Citations: 2     Fields:    Translation:HumansCells
    814. Kalaria RN, Bhatti SU, Lust WD, Perry G. The amyloid precursor protein in ischemic brain injury and chronic hypoperfusion. Ann N Y Acad Sci. 1993 Sep 24; 695:190-3. PMID: 8239281.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    815. Kawai M, Kalaria RN, Cras P, Siedlak SL, Velasco ME, Shelton ER, Chan HW, Greenberg BD, Perry G. Degeneration of vascular muscle cells in cerebral amyloid angiopathy of Alzheimer disease. Brain Res. 1993 Sep 24; 623(1):142-6. PMID: 8221082.
      Citations: 34     Fields:    Translation:Humans
    816. Kalaria RN, Golde T, Kroon SN, Perry G. Serine protease inhibitor antithrombin III and its messenger RNA in the pathogenesis of Alzheimer's disease. Am J Pathol. 1993 Sep; 143(3):886-93. PMID: 8362984.
      Citations: 9     Fields:    Translation:HumansCells
    817. Sisodia SS, Koo EH, Hoffman PN, Perry G, Price DL. Identification and transport of full-length amyloid precursor proteins in rat peripheral nervous system. J Neurosci. 1993 Jul; 13(7):3136-42. PMID: 8331390.
      Citations: 80     Fields:    Translation:AnimalsCells
    818. Smith MA, Kalaria RN, Perry G. Alpha 1-trypsin immunoreactivity in Alzheimer disease. Biochem Biophys Res Commun. 1993 Jun 15; 193(2):579-84. PMID: 8512558.
      Citations: 3     Fields:    Translation:Humans
    819. DeWitt DA, Silver J, Canning DR, Perry G. Chondroitin sulfate proteoglycans are associated with the lesions of Alzheimer's disease. Exp Neurol. 1993 Jun; 121(2):149-52. PMID: 8339766.
      Citations: 50     Fields:    Translation:HumansCells
    820. Perry G. Neuritic plaques in Alzheimer disease originate from neurofibrillary tangles. Med Hypotheses. 1993 Apr; 40(4):257-8. PMID: 8321160.
      Citations: 3     Fields:    Translation:HumansCells
    821. Harik SI, Hall AK, Richey P, Andersson L, Lundahl P, Perry G. Ontogeny of the erythroid/HepG2-type glucose transporter (GLUT-1) in the rat nervous system. Brain Res Dev Brain Res. 1993 Mar 19; 72(1):41-9. PMID: 8453764.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    822. Villanova M, Kawai M, L?bke U, Oh SJ, Perry G, Six J, Ceuterick C, Martin JJ, Cras P. Rimmed vacuoles of inclusion body myositis and oculopharyngeal muscular dystrophy contain amyloid precursor protein and lysosomal markers. Brain Res. 1993 Feb 19; 603(2):343-7. PMID: 8461987.
      Citations: 13     Fields:    Translation:HumansCells
    823. Kalaria RN, Bhatti SU, Palatinsky EA, Pennington DH, Shelton ER, Chan HW, Perry G, Lust WD. Accumulation of the beta amyloid precursor protein at sites of ischemic injury in rat brain. Neuroreport. 1993 Feb; 4(2):211-4. PMID: 8453062.
      Citations: 27     Fields:    Translation:AnimalsCells
    824. Ciss? S, Perry G, Lacoste-Royal G, Cabana T, Gauvreau D. Immunochemical identification of ubiquitin and heat-shock proteins in corpora amylacea from normal aged and Alzheimer's disease brains. Acta Neuropathol. 1993; 85(3):233-40. PMID: 7681614.
      Citations: 31     Fields:    Translation:HumansCells
    825. Kalaria RN, Kroon SN, Grahovac I, Perry G. Acetylcholinesterase and its association with heparan sulphate proteoglycans in cortical amyloid deposits of Alzheimer's disease. Neuroscience. 1992 Nov; 51(1):177-84. PMID: 1465181.
      Citations: 9     Fields:    Translation:Humans
    826. Tabaton M, Cammarata S, Mandybur T, Richey P, Kawai M, Perry G, Gambetti P. Senile plaques in cerebral amyloid angiopathy show accumulation of amyloid precursor protein without cytoskeletal abnormalities. Brain Res. 1992 Oct 16; 593(2):299-303. PMID: 1280524.
      Citations: 3     Fields:    Translation:HumansCells
    827. Kawai M, Cras P, Perry G. Serial reconstruction of beta-protein amyloid plaques: relationship to microvessels and size distribution. Brain Res. 1992 Oct 02; 592(1-2):278-82. PMID: 1280517.
      Citations: 10     Fields:    Translation:Humans
    828. Perry G, Richey P, Siedlak SL, Galloway P, Kawai M, Cras P. Basic fibroblast growth factor binds to filamentous inclusions of neurodegenerative diseases. Brain Res. 1992 May 08; 579(2):350-2. PMID: 1628222.
      Citations: 8     Fields:    Translation:HumansCells
    829. Aikawa M, Brown A, Smith CD, Tegoshi T, Howard RJ, Hasler TH, Ito Y, Perry G, Collins WE, Webster K. A primate model for human cerebral malaria: Plasmodium coatneyi-infected rhesus monkeys. Am J Trop Med Hyg. 1992 Apr; 46(4):391-7. PMID: 1374220.
      Citations: 23     Fields:    Translation:AnimalsCells
    830. Kawai M, Cras P, Richey P, Tabaton M, Lowery DE, Gonzalez-DeWhitt PA, Greenberg BD, Gambetti P, Perry G. Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease. Am J Pathol. 1992 Apr; 140(4):947-58. PMID: 1562053.
      Citations: 17     Fields:    Translation:HumansCells
    831. Galloway PG, Mulvihill P, Perry G. Filaments of Lewy bodies contain insoluble cytoskeletal elements. Am J Pathol. 1992 Apr; 140(4):809-22. PMID: 1314025.
      Citations: 37     Fields:    Translation:HumansCells
    832. Hirose S, Mohney RP, Mutka SC, Ravi L, Singleton DR, Perry G, Tartakoff AM, Medof ME. Derivation and characterization of glycoinositol-phospholipid anchor-defective human K562 cell clones. J Biol Chem. 1992 Mar 15; 267(8):5272-8. PMID: 1371997.
      Citations: 14     Fields:    Translation:HumansCells
    833. Gollin PA, Kalaria RN, Eikelenboom P, Rozemuller A, Perry G. Alpha 1-antitrypsin and alpha 1-antichymotrypsin are in the lesions of Alzheimer's disease. Neuroreport. 1992 Feb; 3(2):201-3. PMID: 1623174.
      Citations: 33     Fields:    Translation:HumansCells
    834. Perry G, Cras P, Siedlak SL, Tabaton M, Kawai M. Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease. Am J Pathol. 1992 Feb; 140(2):283-90. PMID: 1739122.
      Citations: 19     Fields:    Translation:HumansCells
    835. Cras P, Perry G. Dementia with argyrophilic grains. Ann Neurol. 1991 Dec; 30(6):853-4. PMID: 1724142.
      Citations: 5     Fields:    
    836. Perry G, Siedlak SL, Richey P, Kawai M, Cras P, Kalaria RN, Galloway PG, Scardina JM, Cordell B, Greenberg BD, et al. Association of heparan sulfate proteoglycan with the neurofibrillary tangles of Alzheimer's disease. J Neurosci. 1991 Nov; 11(11):3679-83. PMID: 1941102.
      Citations: 50     Fields:    Translation:HumansCells
    837. Vande Weghe J, Cras P, Kawai M, Siedlak SL, Tabaton M, Greenberg B, Perry G. Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease. Brain Res. 1991 Sep 27; 560(1-2):303-5. PMID: 1760735.
      Citations: 4     Fields:    Translation:HumansCells
    838. Cras P, Kawai M, Siedlak S, Perry G. Microglia are associated with the extracellular neurofibrillary tangles of Alzheimer disease. Brain Res. 1991 Sep 06; 558(2):312-4. PMID: 1782548.
      Citations: 28     Fields:    Translation:HumansCells
    839. Cras P, Kawai M, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Senile plaque neurites in Alzheimer disease accumulate amyloid precursor protein. Proc Natl Acad Sci U S A. 1991 Sep 01; 88(17):7552-6. PMID: 1652752.
      Citations: 96     Fields:    Translation:HumansCells
    840. Gheuens J, Cras P, Perry G, Boons J, Ceuterick-de Groote C, L?bke U, Mercken M, Tabaton M, Gambetti PL, Vandermeeren M, et al. Demonstration of a novel neurofilament associated antigen with the neurofibrillary pathology of Alzheimer and related diseases. Brain Res. 1991 Aug 30; 558(1):43-52. PMID: 1718569.
      Citations: 5     Fields:    Translation:HumansCells
    841. Siedlak SL, Cras P, Kawai M, Richey P, Perry G. Basic fibroblast growth factor binding is a marker for extracellular neurofibrillary tangles in Alzheimer disease. J Histochem Cytochem. 1991 Jul; 39(7):899-904. PMID: 1865106.
      Citations: 18     Fields:    Translation:HumansCells
    842. Kalaria RN, Galloway PG, Perry G. Widespread serum amyloid P immunoreactivity in cortical amyloid deposits and the neurofibrillary pathology of Alzheimer's disease and other degenerative disorders. Neuropathol Appl Neurobiol. 1991 Jun; 17(3):189-201. PMID: 1891063.
      Citations: 21     Fields:    Translation:Humans
    843. Perry G, Kawai M, Tabaton M, Onorato M, Mulvihill P, Richey P, Morandi A, Connolly JA, Gambetti P. Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton. J Neurosci. 1991 Jun; 11(6):1748-55. PMID: 1904481.
      Citations: 30     Fields:    Translation:HumansCells
    844. Tabaton M, Cammarata S, Mancardi G, Manetto V, Autilio-Gambetti L, Perry G, Gambetti P. Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles. Proc Natl Acad Sci U S A. 1991 Mar 15; 88(6):2098-102. PMID: 1706517.
      Citations: 35     Fields:    Translation:HumansCells
    845. Tabaton M, Cammarata S, Mancardi GL, Cordone G, Perry G, Loeb C. Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease. Neurology. 1991 Mar; 41(3):391-4. PMID: 1900925.
      Citations: 7     Fields:    Translation:Humans
    846. Galloway PG, Perry G. Tropomyosin distinguishes Lewy bodies of Parkinson disease from other neurofibrillary pathology. Brain Res. 1991 Feb 15; 541(2):347-9. PMID: 2054646.
      Citations: 3     Fields:    Translation:Humans
    847. Kasper M, Perry G, Stosiek P. Cytokeratin expression in human spinal meninges and ependymal cells. J Hirnforsch. 1991; 32(1):19-25. PMID: 1725782.
      Citations: 5     Fields:    Translation:Humans
    848. Murphy GM, Eng LF, Ellis WG, Perry G, Meissner LC, Tinklenberg JR. Antigenic profile of plaques and neurofibrillary tangles in the amygdala in Down's syndrome: a comparison with Alzheimer's disease. Brain Res. 1990 Dec 24; 537(1-2):102-8. PMID: 1707726.
      Citations: 11     Fields:    Translation:HumansCells
    849. Harik SI, Kalaria RN, Andersson L, Lundahl P, Perry G. Immunocytochemical localization of the erythroid glucose transporter: abundance in tissues with barrier functions. J Neurosci. 1990 Dec; 10(12):3862-72. PMID: 2269888.
      Citations: 35     Fields:    Translation:AnimalsCells
    850. Kawai M, Kalaria RN, Harik SI, Perry G. The relationship of amyloid plaques to cerebral capillaries in Alzheimer's disease. Am J Pathol. 1990 Dec; 137(6):1435-46. PMID: 2260630.
      Citations: 45     Fields:    Translation:Humans
    851. Cras P, Kawai M, Siedlak S, Mulvihill P, Gambetti P, Lowery D, Gonzalez-DeWhitt P, Greenberg B, Perry G. Neuronal and microglial involvement in beta-amyloid protein deposition in Alzheimer's disease. Am J Pathol. 1990 Aug; 137(2):241-6. PMID: 2117395.
      Citations: 48     Fields:    Translation:HumansCells
    852. Galloway PG, Mulvihill P, Siedlak S, Mijares M, Kawai M, Padget H, Kim R, Perry G. Immunochemical demonstration of tropomyosin in the neurofibrillary pathology of Alzheimer's disease. Am J Pathol. 1990 Aug; 137(2):291-300. PMID: 2386197.
      Citations: 15     Fields:    Translation:HumansCells
    853. Harik SI, Kalaria RN, Whitney PM, Andersson L, Lundahl P, Ledbetter SR, Perry G. Glucose transporters are abundant in cells with "occluding" junctions at the blood-eye barriers. Proc Natl Acad Sci U S A. 1990 Jun; 87(11):4261-4. PMID: 2190218.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    854. Kawahara H, Cadrin M, Perry G, Autilio-Gambetti L, Swierenga SH, Metuzals J, Marceau N, French SW. Role of cytokeratin intermediate filaments in transhepatic transport and canalicular secretion. Hepatology. 1990 Mar; 11(3):435-48. PMID: 1690170.
      Citations: 6     Fields:    Translation:AnimalsCells
    855. Galloway PG, Likavec MJ, Perry G. Immunohistochemical recognition of ethylnitrosourea induced rat brain microtumors by anti-Leu 7 monoclonal antibody. Cancer Lett. 1990 Mar; 49(3):243-8. PMID: 1690593.
      Citations: 1     Fields:    Translation:Animals
    856. Galloway PG, Likavec MJ, Perry G. Tropomyosin isoform expression in normal and neoplastic astrocytes. Lab Invest. 1990 Feb; 62(2):163-70. PMID: 1689409.
      Citations: 3     Fields:    Translation:HumansCells
    857. Kasper M, Terpe HJ, Perry G. Age-dependent pattern of intermediate filament protein expression in the human pineal gland. J Hirnforsch. 1990; 31(2):215-21. PMID: 1694197.
      Citations: 1     Fields:    Translation:HumansCells
    858. Tabaton M, Mandybur TI, Perry G, Onorato M, Autilio-Gambetti L, Gambetti P. The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition. Ann Neurol. 1989 Dec; 26(6):771-8. PMID: 2557796.
      Citations: 22     Fields:    Translation:HumansCells
    859. Palmert MR, Siedlak SL, Podlisny MB, Greenberg B, Shelton ER, Chan HW, Usiak M, Selkoe DJ, Perry G, Younkin SG. Soluble derivatives of the beta amyloid protein precursor of Alzheimer's disease are labeled by antisera to the beta amyloid protein. Biochem Biophys Res Commun. 1989 Nov 30; 165(1):182-8. PMID: 2480122.
      Citations: 15     Fields:    Translation:HumansCells
    860. Tabaton M, Cammarata S, Manetto V, Perry G, Mancardi G. Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease. Neurosci Lett. 1989 Sep 11; 103(3):259-62. PMID: 2478932.
      Citations: 1     Fields:    Translation:HumansCells
    861. Galloway PG, Bergeron C, Perry G. The presence of tau distinguishes Lewy bodies of diffuse Lewy body disease from those of idiopathic Parkinson disease. Neurosci Lett. 1989 May 22; 100(1-3):6-10. PMID: 2548130.
      Citations: 18     Fields:    Translation:HumansCells
    862. Perry G, Mulvihill P, Fried VA, Smith HT, Grundke-Iqbal I, Iqbal K. Immunochemical properties of ubiquitin conjugates in the paired helical filaments of Alzheimer disease. J Neurochem. 1989 May; 52(5):1523-8. PMID: 2468737.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    863. Mulvihill P, Perry G. Immunoaffinity demonstration that paired helical filaments of Alzheimer disease share epitopes with neurofilaments, MAP2 and tau. Brain Res. 1989 Apr 10; 484(1-2):150-6. PMID: 2469521.
      Citations: 4     Fields:    Translation:HumansCells
    864. Manetto V, Abdul-Karim FW, Perry G, Tabaton M, Autilio-Gambetti L, Gambetti P. Selective presence of ubiquitin in intracellular inclusions. Am J Pathol. 1989 Mar; 134(3):505-13. PMID: 2466401.
      Citations: 20     Fields:    Translation:HumansCells
    865. Lew EO, Rozdilsky B, Munoz DG, Perry G. A new type of neuronal cytoplasmic inclusion: histological, ultrastructural, and immunocytochemical studies. Acta Neuropathol. 1989; 77(6):599-604. PMID: 2546355.
      Citations: 1     Fields:    Translation:HumansCells
    866. Whitehouse PJ, Gambetti P, Harik SI, Kalaria RN, Perry G, Younkin SI, Tabaton M, Unnerstall JR. Neurochemistry of dementia: establishing the links. Prog Clin Biol Res. 1989; 317:131-42. PMID: 2574868.
      Citations:    Fields:    Translation:HumansCells
    867. Onorato M, Mulvihill P, Connolly J, Galloway P, Whitehouse P, Perry G. Alteration of neuritic cytoarchitecture in Alzheimer disease. Prog Clin Biol Res. 1989; 317:781-9. PMID: 2690122.
      Citations: 18     Fields:    Translation:HumansCells
    868. Autilio-Gambetti L, Morandi A, Kovacs DM, Tabaton M, Schaetzle B, Hauer C, Groger RK, Tykocinski ML, Perry G, Greenberg BD, et al. Amyloid precursor protein in cell cultures: a 130 kDa polypeptide. Prog Clin Biol Res. 1989; 317:985-90. PMID: 2574879.
      Citations:    Fields:    Translation:HumansCells
    869. Perry G, Siedlak S, Mulvihill P, Kancherla M, Mijares M, Kawai M, Gambetti P, Sharma S, Maggiora L, Cornette J, et al. Immunolocalization of the amyloid precursor protein within the senile plaque. Prog Clin Biol Res. 1989; 317:1021-5. PMID: 2513580.
      Citations: 6     Fields:    Translation:HumansCells
    870. Autilio-Gambetti L, Morandi A, Tabaton M, Schaetzle B, Kovacs D, Perry G, Sharma S, Cornette J, Greenberg B, Gambetti P. The amyloid percursor protein of Alzheimer disease is expressed as a 130 kDa polypeptide in various cultured cell types. FEBS Lett. 1988 Dec 05; 241(1-2):94-8. PMID: 2904381.
      Citations: 3     Fields:    Translation:HumansCells
    871. Kalaria RN, Gravina SA, Schmidley JW, Perry G, Harik SI. The glucose transporter of the human brain and blood-brain barrier. Ann Neurol. 1988 Dec; 24(6):757-64. PMID: 3207358.
      Citations: 28     Fields:    Translation:HumansCells
    872. Ohta M, Marceau N, Perry G, Manetto V, Gambetti P, Autilio-Gambetti L, Metuzals J, Kawahara H, Cadrin M, French SW. Ubiquitin is present on the cytokeratin intermediate filaments and Mallory bodies of hepatocytes. Lab Invest. 1988 Dec; 59(6):848-56. PMID: 2462130.
      Citations: 17     Fields:    Translation:AnimalsCells
    873. Manetto V, Sternberger NH, Perry G, Sternberger LA, Gambetti P. Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis. J Neuropathol Exp Neurol. 1988 Nov; 47(6):642-53. PMID: 2459315.
      Citations: 44     Fields:    Translation:HumansCells
    874. Galloway PG, Grundke-Iqbal I, Iqbal K, Perry G. Lewy bodies contain epitopes both shared and distinct from Alzheimer neurofibrillary tangles. J Neuropathol Exp Neurol. 1988 Nov; 47(6):654-63. PMID: 2459316.
      Citations: 36     Fields:    Translation:HumansCells
    875. Perry G, Lipphardt S, Mulvihill P, Kancherla M, Mijares M, Gambetti P, Sharma S, Maggiora L, Cornette J, Lobl T, et al. Amyloid precursor protein in senile plaques of Alzheimer disease. Lancet. 1988 Sep 24; 2(8613):746. PMID: 2901596.
      Citations: 27     Fields:    Translation:HumansAnimals
    876. Tabaton M, Whitehouse PJ, Perry G, Davies P, Autilio-Gambetti L, Gambetti P. Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy. Ann Neurol. 1988 Sep; 24(3):407-13. PMID: 3067653.
      Citations: 17     Fields:    Translation:HumansCells
    877. Tabaton M, Perry G, Autilio-Gambetti L, Manetto V, Gambetti P. Influence of neuronal location on antigenic properties of neurofibrillary tangles. Ann Neurol. 1988 Jun; 23(6):604-10. PMID: 3408241.
      Citations: 9     Fields:    Translation:HumansCells
    878. Manetto V, Perry G, Tabaton M, Mulvihill P, Fried VA, Smith HT, Gambetti P, Autilio-Gambetti L. Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases. Proc Natl Acad Sci U S A. 1988 Jun; 85(12):4501-5. PMID: 2837768.
      Citations: 58     Fields:    Translation:HumansCells
    879. Matsumoto Y, Perry G, Levine RJ, Blanton R, Mahmoud AA, Aikawa M. Paramyosin and actin in schistosomal teguments. Nature. 1988 May 05; 333(6168):76-8. PMID: 3362211.
      Citations: 28     Fields:    Translation:Animals
    880. Atkinson CT, Aikawa M, Perry G, Fujino T, Bennett V, Davidson EA, Howard RJ. Ultrastructural localization of erythrocyte cytoskeletal and integral membrane proteins in Plasmodium falciparum-infected erythrocytes. Eur J Cell Biol. 1988 Feb; 45(2):192-9. PMID: 2966734.
      Citations: 21     Fields:    Translation:AnimalsCells
    881. Perry G, Lambert C. Arachidonic acid metabolism in Ascidia ceratodes eggs: role of lipid peroxidation. Comp Biochem Physiol B. 1988; 90(4):785-9. PMID: 3150323.
      Citations:    Fields:    Translation:AnimalsCells
    882. Matsumoto Y, Perry G, Scheibel LW, Aikawa M. Role of calmodulin in Plasmodium falciparum: implications for erythrocyte invasion by the merozoite. Eur J Cell Biol. 1987 Dec; 45(1):36-43. PMID: 3127214.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    883. Perry G, Mulvihill P, Manetto V, Autilio-Gambetti L, Gambetti P. Immunocytochemical properties of Alzheimer straight filaments. J Neurosci. 1987 Nov; 7(11):3736-8. PMID: 3681409.
      Citations: 15     Fields:    Translation:HumansCells
    884. Perry G, Friedman R, Kang DH, Manetto V, Autilio-Gambetti L, Gambetti P. Antibodies to the neuronal cytoskeleton are elicited by Alzheimer paired helical filament fractions. Brain Res. 1987 Sep 15; 420(2):233-42. PMID: 3676758.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    885. Perry G, Stewart D, Friedman R, Manetto V, Autilio-Gambetti L, Gambetti P. Filaments of Pick's bodies contain altered cytoskeletal elements. Am J Pathol. 1987 Jun; 127(3):559-68. PMID: 3296772.
      Citations: 19     Fields:    Translation:HumansCells
    886. Perry G, Friedman R, Shaw G, Chau V. Ubiquitin is detected in neurofibrillary tangles and senile plaque neurites of Alzheimer disease brains. Proc Natl Acad Sci U S A. 1987 May; 84(9):3033-6. PMID: 3033674.
      Citations: 188     Fields:    Translation:HumansCells
    887. Galloway PG, Perry G, Gambetti P. Hirano body filaments contain actin and actin-associated proteins. J Neuropathol Exp Neurol. 1987 Mar; 46(2):185-99. PMID: 3029338.
      Citations: 46     Fields:    Translation:AnimalsCells
    888. Galloway PG, Perry G, Kosik KS, Gambetti P. Hirano bodies contain tau protein. Brain Res. 1987 Feb 17; 403(2):337-40. PMID: 3103867.
      Citations: 28     Fields:    Translation:HumansCells
    889. Perry G, Wible L, Brinkley BR. Microtubules are not altered in the dystrophic chicken. Exp Cell Res. 1986 Mar; 163(1):266-72. PMID: 3510888.
      Citations:    Fields:    Translation:AnimalsCells
    890. Perry G, Selkoe DJ, Block BR, Stewart D, Autilio-Gambetti L, Gambetti P. Electron microscopic localization of Alzheimer neurofibrillary tangle components recognized by an antiserum to paired helical filaments. J Neuropathol Exp Neurol. 1986 Mar; 45(2):161-8. PMID: 2419516.
      Citations: 8     Fields:    Translation:HumansCells
    891. Kasper M, Goertchen R, Stosiek P, Perry G, Karsten U. Coexistence of cytokeratin, vimentin and neurofilament protein in human choroid plexus. An immunohistochemical study of intermediate filaments in neuroepithelial tissues. Virchows Arch A Pathol Anat Histopathol. 1986; 410(3):173-7. PMID: 2432723.
      Citations: 13     Fields:    Translation:Humans
    892. Perry G, Rizzuto N, Autilio-Gambetti L, Gambetti P. Paired helical filaments from Alzheimer disease patients contain cytoskeletal components. Proc Natl Acad Sci U S A. 1985 Jun; 82(11):3916-20. PMID: 3889918.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    893. Perry G, Epel D. Fertilization stimulates lipid peroxidation in the sea urchin egg. Dev Biol. 1985 Jan; 107(1):58-65. PMID: 3917416.
      Citations: 6     Fields:    Translation:AnimalsCells
    894. Perry G, Epel D. Characterization of a Ca2+-stimulated lipid peroxidizing system in the sea urchin egg. Dev Biol. 1985 Jan; 107(1):47-57. PMID: 3917415.
      Citations: 5     Fields:    Translation:AnimalsCells
    895. Anderson DC, Hughes BJ, Wible LJ, Perry GJ, Smith CW, Brinkley BR. Impaired motility of neonatal PMN leukocytes: relationship to abnormalities of cell orientation and assembly of microtubules in chemotactic gradients. J Leukoc Biol. 1984 Jul; 36(1):1-15. PMID: 6376671.
      Citations: 5     Fields:    Translation:HumansCells
    896. Gambetti P, Autilio-Gambetti L, Perry G, Shecket G, Crane RC. Antibodies to neurofibrillary tangles of Alzheimer's disease raised from human and animal neurofilament fractions. Lab Invest. 1983 Oct; 49(4):430-5. PMID: 6620982.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    897. Pardue RL, Brady RC, Perry GW, Dedman JR. Production of monoclonal antibodies against calmodulin by in vitro immunization of spleen cells. J Cell Biol. 1983 Apr; 96(4):1149-54. PMID: 6833395.
      Citations: 12     Fields:    Translation:AnimalsCellsPHPublic Health
    898. Epel D, Perry G, Schmidt T. Intracellular calcium and fertilization: role of the cation and regulation of intracellular calcium levels. Prog Clin Biol Res. 1982; 91:171-83. PMID: 6292942.
      Citations: 3     Fields:    Translation:AnimalsCells
    899. Perry G, Epel D. Ca2+-stimulated production of H2O2 from naphthoquinone oxidation in Arbacia eggs. Exp Cell Res. 1981 Jul; 134(1):65-72. PMID: 7195822.
      Citations: 8     Fields:    Translation:AnimalsCells
    900. Byrd W, Perry G. Cytochalasin B blocks sperm incorporation but allows activation of the sea urchin egg. Exp Cell Res. 1980 Apr; 126(2):333-42. PMID: 7189151.
      Citations: 1     Fields:    Translation:AnimalsCells
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