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George Perry

TitleDr.
Faculty RankProfessor
InstitutionUniversity of Texas at San Antonio
DepartmentCollege of Sciences
AddressCollege of Sciences
One UTSA Circle
San Antonio TX 78249
Phone(210) 458-8660
Fax(210) 458-5658
ORCID ORCID Icon0000-0002-6547-0172 Additional info
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    Other Positions
    TitleAffiliate Professor
    InstitutionUniversity of Alaska Fairbanks
    DepartmentChemistry and Biochemistry


    Collapse Biography 
    Collapse awards and honors
    2001Distinguished American of Portuguese Ancestry, Portuguese-American Historical and Research Foundation
    2003Hall of Fame, Lompoc High School Alumni Association
    2003Mensch Award , Alzheimer Research Forum
    2003Top 20 Most-Cited Authors in Alzheimer’s Disease, Essential Science Indicators
    2004 - 2007100 Most-Cited Scientists in Neuroscience and Behavior of the Decade, In-cites
    2004Community Service Award, Cleveland Area Chapter of the Alzheimer’s Association
    2007Doctorado Honoris Causa (Hon. D.) , Universidad Arturo Prat, Iquique, Chile
    2007Top 25 Lab Heads in Free Radical Research, Free Radical Lab Registry
    2007Zenith Fellow, Alzheimer’s Association
    2008Denham Harman Research Award, American Aging Association
    2008ISI Highly Cited.com, Neuroscience
    2009Foreign Corresponding Member, Royal Spanish Academy of Sciences
    2009Top 100 Alzheimer’s Disease Investigators
    2010Alzheimer Award / Alzheimer Medal, Journal of Alzheimer’s Disease
    2010Corresponding Member, Mexican Academy of Sciences
    2010Distinguished Professional Mentor Award, Society for the Advancement of Chicanos and Native American Scientists (SACNAS)
    2011Alzheimer Award / Alzheimer Medal, Journal of Alzheimer’s Disease
    2011Chartered Biologist (CBiol), Society of Biology
    2011Fellow, Linnean Society of London
    2011Fellow, Microscopy Society of America
    2011Fellow, Royal College of Pathologists
    2011Fellow, Royal Society of Biology
    2011Fellow, Royal Society of Chemistry
    2011Foreign Corresponding Member, Academy of Sciences of Lisbon
    2011National Honor Plaque of Panama for Exceptional Contribution to “Neuroscience", Secretar?a nacional de Ciencia, Technolog?a e Innovación (SENACYT)
    2011Senior Investigator Award, International College of Geriatric Psychoneuropharmacology (ICGP)
    2011Top 20 Alzheimer’s Disease Authors,
    2012Charter and Life Member, Phi Kappa Phi
    2012Chartered Chemist (CChem), Royal Society of Chemistry
    2012Chartered Scientist (CSci), Royal Society of Biology
    2012Fulbright Senior Scholar Specialist Program, US Deparment of State
    2012Gente Notavel(Notable People), Azorean Spirit, SATA Inflight Magazine
    2012Notaveis dos Azores, Governo dos Azores
    2012Outstanding Service Award, International Conference on Research in Applied Computation Symposium
    2012Scientist of the Year, Portuguese Tribune
    2013Distinguished Chair in Neurobiology, Semmes Foundation
    2013Leading Expert-Alzheimer Disease, Expertscape
    2013Martin Goland Award, Sigma XI, Alamo Chapter
    2014Fellow, Royal Microscopical Society, (FRMS)
    2014Fellow, Royal Society of the Encouragement of Arts, Manufactures and Commerce
    2014UDAAN-Lifetime Achievement Award, International Journal of Humanities, Engineering and Pharmaceutical Sciences..., India
    2015Distinguished Fellow and President, International Engineering and Technology Institute
    2015Fellow, Association of Biotechnology and Pharmacy (India), FABAP
    2016Fellow, Texas Academy of Sciences
    2016Lifetime Achievement, World Automation Congress
    2016Semmes Distinguished University Chair in Neurobiology, Semmes Foundation
    2017Albert Nelson Marquis Lifetime Achievement Award, Marquis Who''s Who
    2017Annual Scientific Award, International Engineering and Technology Institute
    2017Chartered Science Teacher (CSciTeach), Royal Society of Biology
    2017Fellow, World Academy of Medical Sciences
    2017Member, EU Academy of Sciences
    2018Counselors, Conselho da Diáspora Portuguesa
    2018Distinction of Excellence Award in Alzheimer''s Disease Research, Alzheimer Association:
    2018Honorable Director, Global Listening Centre
    2020Texas Distinguished Scientist, Texas Academy of Sciences
    2021Rous-Whipple Award, American Society for Investigative Pathology
    2020Distinguished Member, Japanese Society of Neurology

    Collapse Overview 
    Collapse overview
    George Perry is former dean of the College of Sciences and the Semmes Foundation Distinguished University Chair in Neurobiology at The University of Texas at San Antonio. Dr. Perry is recognized in the field of Alzheimer’s disease research particularly for his work on oxidative metabolism.

    Dr. Perry is distinguished as one of the top Alzheimer’s disease researchers with over 1,000 publications, and one of the top 100 most-cited scientists in neuroscience and behavior (Over 101,000 citations, H=158), as well as the Expertscape Leading Expert in Alzheimer’s disease. Perry serves as editor for numerous journals and is Editor-in-Chief for the Journal of Alzheimer's Disease. He is a fellow of the American Association for the Advancement of Sciences, International Engineering and Technology Institute, Texas Academy of Sciences, and Microscopy Society of America, a Fulbright Senior Specialist, as well as a member of the Dana Alliance for Brain Initiatives. Perry is also recognized internationally: he is a Foreign Member of the Spanish Royal Academy of Sciences, the Academy of Science Lisbon, and the Mexican National Academy of Sciences. He is also a recipient of the National Plaque of Honor from the Republic of Panama Ministry of Science and Technology., Rous-Whipple award from American Society for Investigative Pathology, Distinguished Member of the Japanese Society of Neurology.

    Dr. Perry received his BA in Zoology from the University of California, Santa Barbara followed by his Ph.D. in Marine Biology from Scripps Institution of Oceanography. He then received a postdoctoral fellowship in the Department of Cell Biology at Baylor College of Medicine where he laid the foundation for his observations of abnormalities in cell structures.

    Collapse Research 
    Collapse research activities and funding
    K04AG000415     (PERRY, GEORGE)Apr 1, 1988 - Aug 31, 1993
    NIH
    AMYLOID PRECURSOR IN ALZHEIMER DISEASE
    Role: Principal Investigator
    R01AG007552     (PERRY, GEORGE)Apr 1, 1988 - Mar 31, 1994
    NIH
    AMYLOID PRECURSOR IN ALZHEIMER DISEASE
    Role: Principal Investigator
    R01AG009287     (PERRY, GEORGE)Sep 1, 1990 - Nov 30, 2000
    NIH
    NEUROFIBRILLARY PATHOLOGY IN ALZHEIMER DISEASE
    Role: Principal Investigator
    G12RR013646     (TSIN, ANDREW T C)Sep 30, 1998 - Jun 30, 2015
    NIH
    RCMI Center for Interdiscplinary Health Research CIHR
    Role: Co-Investigator
    G12MD007591     (PERRY, GEORGE)Sep 30, 1998 - Jun 30, 2017
    NIH
    RCMI Center for Interdiscplinary Health Research CIHR
    Role: Co-Investigator

    Collapse Featured Content 
    Collapse Twitter

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Shobeiri P, Alilou S, Jaberinezhad M, Zare F, Karimi N, Maleki S, Teixeira AL, Perry G, Rezaei N. Circulating long non-coding RNAs as novel diagnostic biomarkers for Alzheimer's disease (AD): A systematic review and meta-analysis. PLoS One. 2023; 18(3):e0281784. PMID: 36947499.
      Citations: 1     Fields:    Translation:Humans
    2. Atwood CS, Perry G. Playing Russian Roulette with Alzheimer's Disease Patients: Do the Cognitive Benefits of Lecanemab Outweigh the Risk of Edema, Stroke and Encephalitis? J Alzheimers Dis. 2023; 92(3):799-801. PMID: 36847013.
      Citations: 2     Fields:    Translation:Humans
    3. Plascencia-Villa G, Perry G. Lessons from antiamyloid-? immunotherapies in Alzheimer's disease. Handb Clin Neurol. 2023; 193:267-292. PMID: 36803816.
      Citations: 1     Fields:    Translation:Humans
    4. Perry G. Alzheimer's Disease: Not Just for the Aged? J Alzheimers Dis. 2023; 91(3):923-924. PMID: 36710685.
      Citations:    Fields:    Translation:Humans
    5. Perry G. Beyond the Clouds: B.R. Brinkley (1936-2020). J Alzheimers Dis. 2023; 91(3):913. PMID: 36710686.
      Citations:    Fields:    
    6. Obrenovich M, Singh SK, Li Y, Perry G, Siddiqui B, Haq W, Reddy VP. Natural Product Co-Metabolism and the Microbiota-Gut-Brain Axis in Age-Related Diseases. Life (Basel). 2022 Dec 23; 13(1). PMID: 36675988.
      Citations:    
    7. Hsieh KL, Plascencia-Villa G, Lin KH, Perry G, Jiang X, Kim Y. Synthesize heterogeneous biological knowledge via representation learning for Alzheimer's disease drug repurposing. iScience. 2023 Jan 20; 26(1):105678. PMID: 36594024.
      Citations:    
    8. Vall?s-Saiz L, Ruiz-Gabarre D, Garc?a-Escudero V, Perry G, Avila J, Hern?ndez F. Mouse and Human Tau Expression in Different Brain Areas. J Alzheimers Dis Rep. 2022; 6(1):677-684. PMID: 36506485.
      Citations:    
    9. Singla RK, De R, Efferth T, Mezzetti B, Sahab Uddin M, Ntie-Kang F, Wang D, Schultz F, Kharat KR, Devkota HP, Battino M, Sur D, Lordan R, Patnaik SS, Tsagkaris C, Sai CS, Tripathi SK, Gaman MA, Ahmed MEO, Gonz?lez-Burgos E, Babiaka SB, Paswan SK, Odimegwu JI, Akram F, Simal-Gandara J, Urquiza MS, Tikhonov A, Mondal H, Singla S, Lonardo SD, Mulholland EJ, Cenanovic M, Maigoro AY, Giampieri F, Lee S, Tzvetkov NT, Louka AM, Verma P, Chopra H, Olea SP, Khan J, Alvarez Suarez JM, Zheng X, Tomczyk M, Sabnani MK, Medina CDV, Khalid GM, Boyina HK, Georgiev MI, Supuran CT, Sobarzo-S?nchez E, Fan TP, Pittala V, Sureda A, Braidy N, Russo GL, Vacca RA, Banach M, Lizard G, Zarrouk A, Hammami S, Orhan IE, Aggarwal BB, Perry G, Miller MJ, Heinrich M, Bishayee A, Kijjoa A, Arkells N, Bredt D, Wink M, Fiebich BL, Kiran G, Yeung AWK, Gupta GK, Santini A, Lucarini M, Durazzo A, El-Demerdash A, Dinkova-Kostova AT, Cifuentes A, Souto EB, Zubair MAM, Badhe P, Echeverr?a J, Horbanczuk JO, Horbanczuk OK, Sheridan H, Sheshe SM, Witkowska AM, Abu-Reidah IM, Riaz M, Ullah H, Oladipupo AR, Lopez V, Sethiya NK, Shrestha BG, Ravanan P, Gupta SC, Alzahrani QE, Dama Sreedhar P, Xiao J, Moosavi MA, Subramani PA, Singh AK, Chettupalli AK, Patra JK, Singh G, Karpinski TM, Al-Rimawi F, Abiri R, Ahmed AF, Barreca D, Vats S, Amrani S, Fimognari C, Mocan A, Hritcu L, Semwal P, Shiblur Rahaman M, Emerald M, Akinrinde AS, Singh A, Joshi A, Joshi T, Khan SY, Balla GOA, Lu A, Pai SR, Ghzaiel I, Acar N, Es-Safi NE, Zengin G, Kureshi AA, Sharma AK, Baral B, Rani N, Jeandet P, Gulati M, Kapoor B, Mohanta YK, Emam-Djomeh Z, Onuku R, Depew JR, Atrooz OM, Goh BH, Andrade JC, Konwar B, Shine VJ, Ferreira JMLD, Ahmad J, Chaturvedi VK, Skalicka-Wozniak K, Sharma R, Gautam RK, Granica S, Parisi S, Kumar R, Atanasov AG, Shen B. The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis. Phytomedicine. 2023 Jan; 108:154520. PMID: 36334386.
      Citations: 11     Fields:    Translation:Humans
    10. Mishra SK, Balendra V, Esposto J, Obaid AA, Maccioni RB, Jha NK, Perry G, Moustafa M, Al-Shehri M, Singh MP, Khan AA, Vamanu E, Singh SK. Therapeutic Antiaging Strategies. Biomedicines. 2022 Oct 08; 10(10). PMID: 36289777.
      Citations:    
    11. Plascencia-Villa G, Perry G. Neuropathologic Changes Provide Insights into Key Mechanisms of Alzheimer Disease and Related Dementia. Am J Pathol. 2022 10; 192(10):1340-1346. PMID: 35931209.
      Citations: 6     Fields:    Translation:HumansCells
    12. Correia SC, Alves MG, Oliveira PF, Casadesus G, LaManna J, Perry G, Moreira PI. Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria. Antioxid Redox Signal. 2022 10; 37(10-12):739-757. PMID: 35316086.
      Citations: 2     Fields:    Translation:AnimalsCells
    13. Marciniak S, Bergey CM, Silva AM, Haluszko A, Furmanek M, Veselka B, Velem?nsk? P, Vercellotti G, Wahl J, Zarina G, Longhi C, Kol?r J, Garrido-Pena R, Flores-Fern?ndez R, Herrero-Corral AM, Simalcsik A, M?ller W, Sheridan A, Miliauskiene ?, Jankauskas R, Moiseyev V, K?hler K, Kir?ly ?, Gamarra B, Cheronet O, Szever?nyi V, Kiss V, Szeniczey T, Kiss K, Zoffmann ZK, Ko?s J, Hellebrandt M, Maier RM, Dombor?czki L, Virag C, Novak M, Reich D, Hajdu T, von Cramon-Taubadel N, Pinhasi R, Perry GH. An integrative skeletal and paleogenomic analysis of stature variation suggests relatively reduced health for early European farmers. Proc Natl Acad Sci U S A. 2022 04 12; 119(15):e2106743119. PMID: 35389750.
      Citations: 6     Fields:    Translation:Humans
    14. Mirzayi P, Shobeiri P, Kalantari A, Perry G, Rezaei N. Optogenetics: implications for Alzheimer's disease research and therapy. Mol Brain. 2022 02 23; 15(1):20. PMID: 35197102.
      Citations: 5     Fields:    Translation:Humans
    15. Sena CM, Sei?a R, Perry G. Editorial: Oxidative Stress Revisited-Major Role in Vascular Diseases, Volume II. Front Physiol. 2021; 12:826129. PMID: 35095578.
      Citations:    
    16. Mandal PK, Perry G. SWADESH: A Comprehensive Platform for Multimodal Data and Analytics for Advanced Research in Alzheimer's Disease and Other Brain Disorders. J Alzheimers Dis. 2022; 85(1):1-5. PMID: 34744083.
      Citations:    Fields:    Translation:Humans
    17. Whitehouse P, Gandy S, Saini V, George DR, Larson EB, Alexander GC, Avorn J, Brownlee S, Camp C, Chertkow H, Fugh-Berman A, Howard R, Kesselheim A, Langa KM, Perry G, Richard E, Schneider L. Making the Case for Accelerated Withdrawal of Aducanumab. J Alzheimers Dis. 2022; 87(3):1003-1007. PMID: 35404287.
      Citations: 8     Fields:    Translation:Humans
    18. Xolalpa-Cueva L, Garc?a-Carlos CA, Villase?or-Zepeda R, Orta-Salazar E, D?az-Cintra S, Pe?a-Ortega F, Perry G, Mondrag?n-Rodr?guez S. Hyperphosphorylated Tau Relates to Improved Cognitive Performance and Reduced Hippocampal Excitability in the Young rTg4510 Mouse Model of Tauopathy. J Alzheimers Dis. 2022; 87(2):529-543. PMID: 35342085.
      Citations:    Fields:    Translation:HumansAnimals
    19. Ashford JW, Schmitt FA, Bergeron MF, Bayley PJ, Clifford JO, Xu Q, Liu X, Zhou X, Kumar V, Buschke H, Dean M, Finkel SI, Hyer L, Perry G. Now is the Time to Improve Cognitive Screening and Assessment for Clinical and Research Advancement. J Alzheimers Dis. 2022; 87(1):305-315. PMID: 35431257.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    20. Wang Q, Davis PB, Qi X, Chen SG, Gurney ME, Perry G, Doraiswamy PM, Xu R. Gut-microbiota-microglia-brain interactions in Alzheimer's disease: knowledge-based, multi-dimensional characterization. Alzheimers Res Ther. 2021 10 20; 13(1):177. PMID: 34670619.
      Citations: 5     Fields:    Translation:AnimalsCells
    21. Ashkarran AA, Hosseini A, Loloee R, Perry G, Lee KB, Lund M, Ejtehadi MR, Mahmoudi M. Conformation- and phosphorylation-dependent electron tunnelling across self-assembled monolayers of tau peptides. J Colloid Interface Sci. 2022 Jan 15; 606(Pt 2):2038-2050. PMID: 34749450.
      Citations:    Fields:    Translation:Cells
    22. Zheng C, Fillmore NR, Ramos-Cejudo J, Brophy M, Osorio R, Gurney ME, Qiu WQ, Au R, Perry G, Dubreuil M, Chen SG, Qi X, Davis PB, Do N, Xu R. Potential long-term effect of tumor necrosis factor inhibitors on dementia risk: A propensity score matched retrospective cohort study in US veterans. Alzheimers Dement. 2022 06; 18(6):1248-1259. PMID: 34569707.
      Citations: 2     Fields:    Translation:Humans
    23. Mahdiabadi S, Momtazmanesh S, Perry G, Rezaei N. Immune modulations and immunotherapies for Alzheimer's disease: a comprehensive review. Rev Neurosci. 2022 06 27; 33(4):365-381. PMID: 34506700.
      Citations: 4     Fields:    Translation:Humans
    24. Hampel H, Hardy J, Blennow K, Chen C, Perry G, Kim SH, Villemagne VL, Aisen P, Vendruscolo M, Iwatsubo T, Masters CL, Cho M, Lannfelt L, Cummings JL, Vergallo A. The Amyloid-? Pathway in Alzheimer's Disease. Mol Psychiatry. 2021 10; 26(10):5481-5503. PMID: 34456336.
      Citations: 179     Fields:    Translation:Humans
    25. Perry GH. Evolutionary medicine. Elife. 2021 07 22; 10. PMID: 34291730.
      Citations: 3     Fields:    Translation:Humans
    26. Bajic V, Misic N, Stankovic I, Zaric B, Perry G. Alzheimer's and Consciousness: How Much Subjectivity Is Objective? Neurosci Insights. 2021; 16:26331055211033869. PMID: 34350401.
      Citations:    
    27. Marciniak S, Mughal MR, Godfrey LR, Bankoff RJ, Randrianatoandro H, Crowley BE, Bergey CM, Muldoon KM, Randrianasy J, Raharivololona BM, Schuster SC, Malhi RS, Yoder AD, Louis EE, Kistler L, Perry GH. Evolutionary and phylogenetic insights from a nuclear genome sequence of the extinct, giant, "subfossil" koala lemur Megaladapis edwardsi. Proc Natl Acad Sci U S A. 2021 06 29; 118(26). PMID: 34162703.
      Citations: 3     Fields:    Translation:AnimalsCells
    28. Henry Akintobi T, Sheikhattari P, Shaffer E, Evans CL, Braun KL, Sy AU, Mancera B, Campa A, Miller ST, Sarpong D, Holliday R, Jimenez-Chavez J, Khan S, Hinton C, Sellars-Bates K, Ajewole V, Teufel-Shone NI, McMullin J, Suther S, Kimbro KS, Taylor L, Velez Vega CM, Williams C, Perry G, Zuchner S, Marzan Rodriguez M, Tchounwou PB. Community Engagement Practices at Research Centers in U.S. Minority Institutions: Priority Populations and Innovative Approaches to Advancing Health Disparities Research. Int J Environ Res Public Health. 2021 06 21; 18(12). PMID: 34205781.
      Citations: 4     Fields:    Translation:Humans
    29. Wang C, Shao C, Zhang L, Siedlak SL, Meabon JS, Peskind ER, Lu Y, Wang W, Perry G, Cook DG, Zhu X. Oxidative Stress Signaling in Blast TBI-Induced Tau Phosphorylation. Antioxidants (Basel). 2021 Jun 15; 10(6). PMID: 34203583.
      Citations:    
    30. Everett J, Lermyte F, Brooks J, Tjendana-Tjhin V, Plascencia-Villa G, Hands-Portman I, Donnelly JM, Billimoria K, Perry G, Zhu X, Sadler PJ, O'Connor PB, Collingwood JF, Telling ND. Biogenic metallic elements in the human brain? Sci Adv. 2021 06; 7(24). PMID: 34108207.
      Citations: 15     Fields:    
    31. Talbert PY, Perry G, Ricks-Santi L, Soto de Laurido LE, Shaheen M, Seto T, Kumar D, Quarshie A, Thakar M, Rubio DM. Challenges and Strategies of Successful Mentoring: The Perspective of LEADS Scholars and Mentors from Minority Serving Institutions. Int J Environ Res Public Health. 2021 06 07; 18(11). PMID: 34200278.
      Citations: 2     Fields:    Translation:Humans
    32. Arner AM, Grogan KE, Grabowski M, Reyes-Centeno H, Perry GH. Patterns of recent natural selection on genetic loci associated with sexually differentiated human body size and shape phenotypes. PLoS Genet. 2021 06; 17(6):e1009562. PMID: 34081690.
      Citations: 1     Fields:    Translation:Humans
    33. Pappolla MA, Perry G, Fang X, Zagorski M, Sambamurti K, Poeggeler B. Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease. Neurobiol Dis. 2021 08; 156:105403. PMID: 34087380.
      Citations: 11     Fields:    Translation:HumansAnimals
    34. Hampel H, Nistic? R, Seyfried NT, Levey AI, Modeste E, Lemercier P, Baldacci F, Toschi N, Garaci F, Perry G, Emanuele E, Valenzuela PL, Lucia A, Urbani A, Sancesario GM, Mapstone M, Corbo M, Vergallo A, Lista S. Omics sciences for systems biology in Alzheimer's disease: State-of-the-art of the evidence. Ageing Res Rev. 2021 08; 69:101346. PMID: 33915266.
      Citations: 34     Fields:    Translation:Humans
    35. Hernandez M, Perry GH. Scanning the human genome for "signatures" of positive selection: Transformative opportunities and ethical obligations. Evol Anthropol. 2021 Mar; 30(2):113-121. PMID: 33788352.
      Citations: 3     Fields:    Translation:Humans
    36. Sullivan AP, Marciniak S, O'Dea A, Wake TA, Perry GH. Modern, archaeological, and paleontological DNA analysis of a human-harvested marine gastropod (Strombus pugilis) from Caribbean Panama. Mol Ecol Resour. 2021 Jul; 21(5):1517-1528. PMID: 33595921.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    37. Orkin JD, Montague MJ, Tejada-Martinez D, de Manuel M, Del Campo J, Cheves Hernandez S, Di Fiore A, Fontsere C, Hodgson JA, Janiak MC, Kuderna LFK, Lizano E, Martin MP, Niimura Y, Perry GH, Valverde CS, Tang J, Warren WC, de Magalh?es JP, Kawamura S, Marqu?s-Bonet T, Krawetz R, Melin AD. The genomics of ecological flexibility, large brains, and long lives in capuchin monkeys revealed with fecalFACS. Proc Natl Acad Sci U S A. 2021 02 16; 118(7). PMID: 33574059.
      Citations: 16     Fields:    Translation:Animals
    38. ?ivkovic L, Bajic V, Cabarkapa-Pirkovic A, Dekanski D, Forbes-Hern?ndez TY, Zlatkovic-?venda M, Perry G, Spremo-Potparevic B. Strawberry (Fragaria ananassa duch.) Alba extract attenuates DNA damage in lymphocytes of patients with Alzheimer's disease. J Food Biochem. 2021 04; 45(4):e13637. PMID: 33547659.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    39. Mart?n-Maestro P, Gargini R, Garc?a E, Perry G, Avila J, Garc?a-Escudero V. Corrigendum to "Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease". Oxid Med Cell Longev. 2021; 2021:1643631. PMID: 33510835.
      Citations: 1     Fields:    
    40. Mart?nez-Maldonado A, Ontiveros-Torres M?, Harrington CR, Montiel-Sosa JF, Prandiz RG, Bocanegra-L?pez P, Sorsby-Vargas AM, Bravo-Mu?oz M, Flor?n-Gardu?o B, Villanueva-Fierro I, Perry G, Garc?s-Ram?rez L, de la Cruz F, Mart?nez-Robles S, Pacheco-Herrero M, Luna-Mu?oz J. Molecular Processing of Tau Protein in Progressive Supranuclear Palsy: Neuronal and Glial Degeneration. J Alzheimers Dis. 2021; 79(4):1517-1531. PMID: 33459640.
      Citations: 4     Fields:    Translation:HumansCells
    41. Moradian N, Moallemian M, Delavari F, Sedikides C, Camargo CA, Torres PJ, Sorooshian A, Mehdiabadi SP, Nieto JJ, Bordas S, Ahmadieh H, Abdollahi M, Hamblin MR, Sellke FW, Cuzick J, Biykem B, Schreiber M, Eshrati B, Perry G, Montazeri A, Saboury AA, Kelishadi R, Sahebkar A, Moosavi-Movahed AA, Vatandoost H, Gorji-Bandpy M, Mobasher B, Rezaei N. Interdisciplinary Approaches to COVID-19. Adv Exp Med Biol. 2021; 1318:923-936. PMID: 33973220.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    42. Wang L, Liu M, Gao J, Smith AM, Fujioka H, Liang J, Perry G, Wang X. Mitochondrial Fusion Suppresses Tau Pathology-Induced Neurodegeneration and Cognitive Decline. J Alzheimers Dis. 2021; 84(3):1057-1069. PMID: 34602490.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    43. Nunomura A, Perry G. RNA and Oxidative Stress in Alzheimer's Disease: Focus on microRNAs. Oxid Med Cell Longev. 2020; 2020:2638130. PMID: 33312335.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    44. Avila J, Perry G. A Multilevel View of the Development of Alzheimer's Disease. Neuroscience. 2021 03 01; 457:283-293. PMID: 33246061.
      Citations: 20     Fields:    Translation:HumansCells
    45. Forero DA, Lopez-Leon S, Perry G. A brief guide to the science and art of writing manuscripts in biomedicine. J Transl Med. 2020 11 10; 18(1):425. PMID: 33167977.
      Citations: 7     Fields:    
    46. Ashford JW, Gold JE, Huenergardt MA, Katz RBA, Strand SE, Bolanos J, Wheeler CJ, Perry G, Smith CJ, Steinman L, Chen MY, Wang JC, Ashford CB, Roth WT, Cheng JJ, Chao S, Jennings J, Sipple D, Yamamoto V, Kateb B, Earnest DL. MMR Vaccination: A Potential Strategy to Reduce Severity and Mortality of COVID-19 Illness. Am J Med. 2021 02; 134(2):153-155. PMID: 33198951.
      Citations: 17     Fields:    Translation:Humans
    47. Hernandez M, Shenk MK, Perry GH. Factors influencing taxonomic unevenness in scientific research: a mixed-methods case study of non-human primate genomic sequence data generation. R Soc Open Sci. 2020 Sep; 7(9):201206. PMID: 33047065.
      Citations:    
    48. Momtazmanesh S, Perry G, Rezaei N. Toll-like receptors in Alzheimer's disease. J Neuroimmunol. 2020 11 15; 348:577362. PMID: 32858428.
      Citations: 13     Fields:    Translation:HumansAnimals
    49. Kelley AR, Colley M, Dyer S, Bach SBH, Zhu X, Perry G. Ethanol-Fixed, Paraffin-Embedded Tissue Imaging: Implications for Alzheimer's Disease Research. J Am Soc Mass Spectrom. 2020 Dec 02; 31(12):2416-2420. PMID: 32803969.
      Citations: 4     Fields:    Translation:Humans
    50. Nami M, Gadad BS, Chong L, Ghumman U, Misra A, Gadad SS, Kumar D, Perry G, Abraham SJK, Rao KS. The Interrelation of Neurological and Psychological Symptoms of COVID-19: Risks and Remedies. J Clin Med. 2020 Aug 13; 9(8). PMID: 32823540.
      Citations:    
    51. Plascencia-Villa G, Perry G. Status and future directions of clinical trials in Alzheimer's disease. Int Rev Neurobiol. 2020; 154:3-50. PMID: 32739008.
      Citations: 12     Fields:    Translation:Humans
    52. Plascencia-Villa G, Perry G. Preventive and Therapeutic Strategies in Alzheimer's Disease: Focus on Oxidative Stress, Redox Metals, and Ferroptosis. Antioxid Redox Signal. 2021 03 10; 34(8):591-610. PMID: 32486897.
      Citations: 39     Fields:    Translation:HumansCells
    53. Gonz?lez-S?nchez M, Bartolome F, Antequera D, Puertas-Mart?n V, Gonz?lez P, G?mez-Grande A, Llamas-Velasco S, Herrero-San Mart?n A, P?rez-Mart?nez D, Villarejo-Galende A, Atienza M, Palomar-Bonet M, Cantero JL, Perry G, Orive G, Iba?ez B, Bueno H, Fuster V, Carro E. Decreased salivary lactoferrin levels are specific to Alzheimer's disease. EBioMedicine. 2020 Jul; 57:102834. PMID: 32586758.
      Citations: 35     Fields:    Translation:Humans
    54. Veurink G, Perry G, Singh SK. Role of antioxidants and a nutrient rich diet in Alzheimer's disease. Open Biol. 2020 06; 10(6):200084. PMID: 32543351.
      Citations: 22     Fields:    Translation:Humans
    55. Messman RD, Contreras-Correa ZE, Paz HA, Perry G, Lemley CO. Vaginal bacterial community composition and concentrations of estradiol at the time of artificial insemination in Brangus heifers. J Anim Sci. 2020 Jun 01; 98(6). PMID: 32515480.
      Citations: 11     Fields:    Translation:AnimalsCells
    56. Wang W, Zhao F, Ma X, Perry G, Zhu X. Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: recent advances. Mol Neurodegener. 2020 05 29; 15(1):30. PMID: 32471464.
      Citations: 275     Fields:    Translation:HumansAnimalsCells
    57. Obrenovich M, Jaworski H, Tadimalla T, Mistry A, Sykes L, Perry G, Bonomo RA. The Role of the Microbiota-Gut-Brain Axis and Antibiotics in ALS and Neurodegenerative Diseases. Microorganisms. 2020 May 23; 8(5). PMID: 32456229.
      Citations:    
    58. Obrenovich M, Tabrez S, Siddiqui B, McCloskey B, Perry G. The Microbiota-Gut-Brain Axis-Heart Shunt Part II: Prosaic Foods and the Brain-Heart Connection in Alzheimer Disease. Microorganisms. 2020 Mar 31; 8(4). PMID: 32244373.
      Citations:    
    59. Yeung AWK, Tzvetkov NT, Georgieva MG, Ognyanov IV, Kordos K, J?zwik A, K?hl T, Perry G, Petralia MC, Mazzon E, Atanasov AG. Reactive Oxygen Species and Their Impact in Neurodegenerative Diseases: Literature Landscape Analysis. Antioxid Redox Signal. 2021 02 10; 34(5):402-420. PMID: 32030995.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    60. Mondrag?n-Rodr?guez S, Ordaz B, Orta-Salazar E, D?az-Cintra S, Pe?a-Ortega F, Perry G. Hippocampal Unicellular Recordings and Hippocampal-dependent Innate Behaviors in an Adolescent Mouse Model of Alzheimer's disease. Bio Protoc. 2020 Feb 20; 10(4):e3529. PMID: 33654753.
      Citations:    
    61. Reddy VP, Aryal P, Robinson S, Rafiu R, Obrenovich M, Perry G. Polyphenols in Alzheimer's Disease and in the Gut-Brain Axis. Microorganisms. 2020 Jan 31; 8(2). PMID: 32023969.
      Citations:    
    62. Reyes-Pablo AE, Campa-C?rdoba BB, Luna-Viramontes NI, Ontiveros-Torres M?, Villanueva-Fierro I, Bravo-Mu?oz M, S?enz-Ibarra B, Barbosa O, Guadarrama-Ort?z P, Garc?s-Ram?rez L, de la Cruz F, Harrington CR, Mart?nez-Robles S, Gonz?lez-Ballesteros E, Perry G, Pacheco-Herrero M, Luna-Mu?oz J. National Dementia BioBank: A Strategy for the Diagnosis and Study of Neurodegenerative Diseases in M?xico. J Alzheimers Dis. 2020; 76(3):853-862. PMID: 32568191.
      Citations: 2     Fields:    Translation:Humans
    63. Hernandes-Alejandro M, Monta?o S, Harrington CR, Wischik CM, Salas-Casas A, Cortes-Reynosa P, P?rez Salazar E, Cazares-Apatiga J, Apatiga-Perez R, Ontiveros Torres M?, Perry G, Pacheco-Herrero M, Luna-Mu?oz J. Analysis of the Relationship Between Metalloprotease-9 and Tau Protein in Alzheimer's Disease. J Alzheimers Dis. 2020; 76(2):553-569. PMID: 32538846.
      Citations: 8     Fields:    Translation:HumansCells
    64. Perry G. Alzheimer's Disease Patients in the Crosshairs of COVID-19. J Alzheimers Dis. 2020; 76(1):1. PMID: 32623403.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    65. Iverson GL, Gardner AJ, Shultz SR, Solomon GS, McCrory P, Zafonte R, Perry G, Hazrati LN, Keene CD, Castellani RJ. Chronic traumatic encephalopathy neuropathology might not be inexorably progressive or unique to repetitive neurotrauma. Brain. 2019 Dec 01; 142(12):3672-3693. PMID: 31670780.
      Citations: 34     Fields:    Translation:Humans
    66. Gao J, Wang L, Gao C, Arakawa H, Perry G, Wang X. TDP-43 inhibitory peptide alleviates neurodegeneration and memory loss in an APP transgenic mouse model for Alzheimer's disease. Biochim Biophys Acta Mol Basis Dis. 2020 01 01; 1866(1):165580. PMID: 31678156.
      Citations: 12     Fields:    Translation:AnimalsCells
    67. Aiello P, Consalvi S, Poce G, Raguzzini A, Toti E, Palmery M, Biava M, Bernardi M, Kamal MA, Perry G, Peluso I. Dietary flavonoids: Nano delivery and nanoparticles for cancer therapy. Semin Cancer Biol. 2021 02; 69:150-165. PMID: 31454670.
      Citations: 21     Fields:    Translation:HumansAnimals
    68. Gao J, Wang L, Yan T, Perry G, Wang X. TDP-43 proteinopathy and mitochondrial abnormalities in neurodegeneration. Mol Cell Neurosci. 2019 10; 100:103396. PMID: 31445085.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    69. Lopez M, Choin J, Sikora M, Siddle K, Harmant C, Costa HA, Silvert M, Mouguiama-Daouda P, Hombert JM, Froment A, Le Bomin S, Perry GH, Barreiro LB, Bustamante CD, Verdu P, Patin E, Quintana-Murci L. Genomic Evidence for Local Adaptation of Hunter-Gatherers to the African Rainforest. Curr Biol. 2019 09 09; 29(17):2926-2935.e4. PMID: 31402299.
      Citations: 11     Fields:    Translation:HumansCells
    70. Harrison GF, Sanz J, Boulais J, Mina MJ, Grenier JC, Leng Y, Dumaine A, Yotova V, Bergey CM, Nsobya SL, Elledge SJ, Schurr E, Quintana-Murci L, Perry GH, Barreiro LB. Natural selection contributed to immunological differences between hunter-gatherers and agriculturalists. Nat Ecol Evol. 2019 08; 3(8):1253-1264. PMID: 31358949.
      Citations: 11     Fields:    Translation:HumansCells
    71. Luca M, Di Mauro M, Perry G. Neuropsychiatric Disturbances and Diabetes Mellitus: The Role of Oxidative Stress. Oxid Med Cell Longev. 2019; 2019:5698132. PMID: 31354908.
      Citations: 4     Fields:    Translation:Humans
    72. Zavala EI, Rajagopal S, Perry GH, Kruzic I, Ba?ic ?, Parsons TJ, Holland MM. Impact of DNA degradation on massively parallel sequencing-based autosomal STR, iiSNP, and mitochondrial DNA typing systems. Int J Legal Med. 2019 Sep; 133(5):1369-1380. PMID: 31267160.
      Citations: 7     Fields:    Translation:HumansCells
    73. Singh SK, Srivastav S, Castellani RJ, Plascencia-Villa G, Perry G. Neuroprotective and Antioxidant Effect of Ginkgo biloba Extract Against AD and Other Neurological Disorders. Neurotherapeutics. 2019 07; 16(3):666-674. PMID: 31376068.
      Citations: 68     Fields:    Translation:HumansAnimals
    74. Sena CM, Sei?a R, Perry G. Editorial: Oxidative Stress Revisited-Major Role in Vascular Diseases. Front Physiol. 2019; 10:788. PMID: 31293452.
      Citations:    
    75. Jones L, Kumar J, Mistry A, Sankar Chittoor Mana T, Perry G, Reddy VP, Obrenovich M. The Transformative Possibilities of the Microbiota and Mycobiota for Health, Disease, Aging, and Technological Innovation. Biomedicines. 2019 Mar 28; 7(2). PMID: 30925795.
      Citations:    
    76. Samenuk GM, Kelley AR, Perry G, Bach SBH. Rapid method towards proteomic analysis of dried blood spots by MALDI mass spectrometry. Clin Mass Spectrom. 2019 Apr; 12:30-36. PMID: 34841077.
      Citations:    
    77. Ofili EO, Tchounwou PB, Fernandez-Repollet E, Yanagihara R, Akintobi TH, Lee JE, Malouhi M, Garner ST, Hayes TT, Baker AR, Dent AL, Abdelrahim M, Rollins L, Chang SP, Sy A, Hernandez BY, Bullard PL, Noel RJ, Shiramizu B, Hedges JR, Berry MJ, Bond VC, Lima MF, Mokuau N, Kirken RA, Cruz-Correa M, Sarpong DF, Vadgama J, Yates C, Kahn SA, Soliman KF, Perry G, Pezzano M, Luciano CA, Barnett ME, Oyekan A, Kumar D, Norris KC. The Research Centers in Minority Institutions (RCMI) Translational Research Network: Building and Sustaining Capacity for Multi-Site Basic Biomedical, Clinical and Behavioral Research. Ethn Dis. 2019; 29(Suppl 1):135-144. PMID: 30906162.
      Citations: 15     Fields:    Translation:Humans
    78. Castellani RJ, Plascencia-Villa G, Perry G. The amyloid cascade and Alzheimer's disease therapeutics: theory versus observation. Lab Invest. 2019 07; 99(7):958-970. PMID: 30760863.
      Citations: 40     Fields:    Translation:Humans
    79. Espay AJ, Vizcarra JA, Marsili L, Lang AE, Simon DK, Merola A, Josephs KA, Fasano A, Morgante F, Savica R, Greenamyre JT, Cambi F, Yamasaki TR, Tanner CM, Gan-Or Z, Litvan I, Mata IF, Zabetian CP, Brundin P, Fernandez HH, Standaert DG, Kauffman MA, Schwarzschild MA, Sardi SP, Sherer T, Perry G, Leverenz JB. Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases. Neurology. 2019 02 12; 92(7):329-337. PMID: 30745444.
      Citations: 69     Fields:    Translation:Humans
    80. Wang C, Zhao F, Shen K, Wang W, Siedlak SL, Lee HG, Phelix CF, Perry G, Shen L, Tang B, Yan R, Zhu X. The sterol regulatory element-binding protein 2 is dysregulated by tau alterations in Alzheimer disease. Brain Pathol. 2019 07; 29(4):530-543. PMID: 30515907.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    81. Rodriguez RA, Liang H, Chen LY, Plascencia-Villa G, Perry G. Single-channel permeability and glycerol affinity of human aquaglyceroporin AQP3. Biochim Biophys Acta Biomembr. 2019 04 01; 1861(4):768-775. PMID: 30659792.
      Citations: 9     Fields:    Translation:HumansCells
    82. Castellani RJ, Perry G. Tau Biology, Tauopathy, Traumatic Brain Injury, and Diagnostic Challenges. J Alzheimers Dis. 2019; 67(2):447-467. PMID: 30584140.
      Citations: 33     Fields:    Translation:HumansAnimals
    83. Montero-Odasso M, Perry G. Gait Disorders in Alzheimer's Disease and Other Dementias: There is Something in the Way You Walk. J Alzheimers Dis. 2019; 71(s1):S1-S4. PMID: 31476163.
      Citations: 6     Fields:    Translation:Humans
    84. Hampel H, Vergallo A, Perry G, Lista S. The Alzheimer Precision Medicine Initiative. J Alzheimers Dis. 2019; 68(1):1-24. PMID: 30814352.
      Citations: 24     Fields:    Translation:Humans
    85. Perry G. Preface. Mini Rev Med Chem. 2019; 19(1):2. PMID: 30626312.
      Citations:    Fields:    
    86. Tripathy A, Shade A, Erskine B, Bailey K, Grande A, deLong JJ, Perry G, Castellani RJ. No Evidence of Increased Chronic Traumatic Encephalopathy Pathology or Neurodegenerative Proteinopathy in Former Military Service Members: A Preliminary Study. J Alzheimers Dis. 2019; 67(4):1277-1289. PMID: 30741674.
      Citations: 6     Fields:    Translation:Humans
    87. Castellani RJ, Smith M, Bailey K, Perry G, deJong JL. Neuropathology in Consecutive Forensic Consultation Cases with a History of Remote Traumatic Brain Injury. J Alzheimers Dis. 2019; 72(3):683-691. PMID: 31609691.
      Citations: 1     Fields:    Translation:Humans
    88. Hampel H, Lista S, Mango D, Nistic? R, Perry G, Avila J, Hernandez F, Geerts H, Vergallo A. Lithium as a Treatment for Alzheimer's Disease: The Systems Pharmacology Perspective. J Alzheimers Dis. 2019; 69(3):615-629. PMID: 31156173.
      Citations: 17     Fields:    Translation:HumansAnimals
    89. Mohammadi A, Maleki-Jamshid A, Sanooghi D, Milan PB, Rahmani A, Sefat F, Shahpasand K, Soleimani M, Bakhtiari M, Belali R, Faghihi F, Joghataei MT, Perry G, Mozafari M. Correction to: Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders. Mol Neurobiol. 2019 Jan; 56(1):319-320. PMID: 29700773.
      Citations:    Fields:    
    90. Flores-Rodr?guez P, Harrington CR, Wischik CM, Ibarra-Bracamontes V, Zarco N, Navarrete A, Mart?nez-Maldonado A, Guadarrama-Ort?z P, Villanueva-Fierro I, Ontiveros-Torres MA, Perry G, Alonso AD, Floran-Gardu?o B, Segovia J, Luna-Mu?oz J. Phospho-Tau Protein Expression in the Cell Cycle of SH-SY5Y Neuroblastoma Cells: A Morphological Study. J Alzheimers Dis. 2019; 71(2):631-645. PMID: 31424392.
      Citations: 4     Fields:    Translation:HumansCells
    91. Liu M, Wang L, Gao J, Dong Q, Perry G, Ma X, Wang X. Inhibition of Calpain Protects Against Tauopathy in Transgenic P301S Tau Mice. J Alzheimers Dis. 2019; 69(4):1077-1087. PMID: 31156179.
      Citations: 4     Fields:    Translation:AnimalsCells
    92. Sena CM, Leandro A, Azul L, Sei?a R, Perry G. Vascular Oxidative Stress: Impact and Therapeutic Approaches. Front Physiol. 2018; 9:1668. PMID: 30564132.
      Citations:    
    93. Kelley AR, Bach SBH, Perry G. Analysis of post-translational modifications in Alzheimer's disease by mass spectrometry. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2040-2047. PMID: 30481587.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    94. Bergey CM, Lopez M, Harrison GF, Patin E, Cohen JA, Quintana-Murci L, Barreiro LB, Perry GH. Polygenic adaptation and convergent evolution on growth and cardiac genetic pathways in African and Asian rainforest hunter-gatherers. Proc Natl Acad Sci U S A. 2018 11 27; 115(48):E11256-E11263. PMID: 30413626.
      Citations: 15     Fields:    Translation:Humans
    95. Pinho TS, Correia SC, Perry G, Ambr?sio AF, Moreira PI. Diminished O-GlcNAcylation in Alzheimer's disease is strongly correlated with mitochondrial anomalies. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2048-2059. PMID: 30412792.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    96. Peluso I, Palmery M, Yarla NS, Perry G, Kamal MA. From Oxidative Stress to Ageing via Lifestyle, Nutraceuticals, Polypharmacy, and Neuropsychological Factors. Oxid Med Cell Longev. 2018; 2018:6352689. PMID: 30363930.
      Citations: 6     Fields:    Translation:HumansAnimals
    97. Hern?ndez F, Cuadros R, Oll? I, Garc?a C, Ferrer I, Perry G, Avila J. Differences in structure and function between human and murine tau. Biochim Biophys Acta Mol Basis Dis. 2019 08 01; 1865(8):2024-2030. PMID: 31189515.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    98. Wang L, Gao J, Liu J, Siedlak SL, Torres S, Fujioka H, Huntley ML, Jiang Y, Ji H, Yan T, Harland M, Termsarasab P, Zeng S, Jiang Z, Liang J, Perry G, Hoppel C, Zhang C, Li H, Wang X. Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles. Cell Metab. 2018 09 04; 28(3):400-414.e8. PMID: 30017354.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    99. Everett J, Collingwood JF, Tjendana-Tjhin V, Brooks J, Lermyte F, Plascencia-Villa G, Hands-Portman I, Dobson J, Perry G, Telling ND. Nanoscale synchrotron X-ray speciation of iron and calcium compounds in amyloid plaque cores from Alzheimer's disease subjects. Nanoscale. 2018 Jul 05; 10(25):11782-11796. PMID: 29688240.
      Citations: 34     Fields:    Translation:Humans
    100. Liang H, Bourdon AK, Chen LY, Phelix CF, Perry G. Gibbs Free-Energy Gradient along the Path of Glucose Transport through Human Glucose Transporter 3. ACS Chem Neurosci. 2018 11 21; 9(11):2815-2823. PMID: 29865792.
      Citations: 6     Fields:    Translation:HumansCells
    101. Mahmoudi M, Pakpour S, Perry G. Drug-Abuse Nanotechnology: Opportunities and Challenges. ACS Chem Neurosci. 2018 10 17; 9(10):2288-2298. PMID: 29851334.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    102. Mondrag?n-Rodr?guez S, Salas-Gallardo A, Gonz?lez-Pereyra P, Mac?as M, Ordaz B, Pe?a-Ortega F, Aguilar-V?zquez A, Orta-Salazar E, D?az-Cintra S, Perry G, Williams S. Phosphorylation of Tau protein correlates with changes in hippocampal theta oscillations and reduces hippocampal excitability in Alzheimer's model. J Biol Chem. 2018 06 01; 293(22):8462-8472. PMID: 29632073.
      Citations: 29     Fields:    Translation:AnimalsCells
    103. Paley EL, Perry G. Towards an Integrative Understanding of tRNA Aminoacylation-Diet-Host-Gut Microbiome Interactions in Neurodegeneration. Nutrients. 2018 Mar 26; 10(4). PMID: 29587458.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    104. Mohammadi A, Maleki-Jamshid A, Sanooghi D, Milan PB, Rahmani A, Sefat F, Shahpasand K, Soleimani M, Bakhtiari M, Belali R, Faghihi F, Joghataei MT, Perry G, Mozafari M. Transplantation of Human Chorion-Derived Cholinergic Progenitor Cells: a Novel Treatment for Neurological Disorders. Mol Neurobiol. 2019 Jan; 56(1):307-318. PMID: 29549645.
      Citations:    Fields:    Translation:HumansAnimalsCells
    105. Gao J, Wang L, Huntley ML, Perry G, Wang X. Pathomechanisms of TDP-43 in neurodegeneration. J Neurochem. 2018 Feb 27. PMID: 29486049.
      Citations: 68     Fields:    
    106. Hampel H, Vergallo A, Aguilar LF, Benda N, Broich K, Cuello AC, Cummings J, Dubois B, Federoff HJ, Fiandaca M, Genthon R, Haberkamp M, Karran E, Mapstone M, Perry G, Schneider LS, Welikovitch LA, Woodcock J, Baldacci F, Lista S. Precision pharmacology for Alzheimer's disease. Pharmacol Res. 2018 04; 130:331-365. PMID: 29458203.
      Citations: 35     Fields:    Translation:HumansAnimals
    107. Kelley AR, Colley ME, Perry G, Bach SBH. Incubation with Cu(II) and Zn(II) salts enhances MALDI-TOF mass spectra of amyloid-beta and a-synuclein toward in vivo analysis. J Mass Spectrom. 2018 Feb; 53(2):162-171. PMID: 29111606.
      Citations: 1     Fields:    Translation:HumansCells
    108. Jiang S, Nandy P, Wang W, Ma X, Hsia J, Wang C, Wang Z, Niu M, Siedlak SL, Torres S, Fujioka H, Xu Y, Lee HG, Perry G, Liu J, Zhu X. Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex. Mol Neurodegener. 2018 02 01; 13(1):5. PMID: 29391029.
      Citations: 40     Fields:    Translation:AnimalsCells
    109. P?rez-Ibave DC, Rodr?guez-S?nchez IP, Garza-Rodr?guez ML, P?rez-Maya AA, Luna M, Ar?mburo C, Tsin A, Perry G, Mohamed-Noriega K, Mohamed-Noriega J, Cavazos-Adame H, Mohamed-Hamsho J, Barrera-Salda?a HA. Expression of growth hormone gene in the baboon eye. Exp Eye Res. 2018 04; 169:157-169. PMID: 29407222.
      Citations: 4     Fields:    Translation:HumansAnimals
    110. Plascencia-Villa G, Perry G. Iron?ic facts about dementia. J Neurol Neurosurg Psychiatry. 2018 05; 89(5):446-447. PMID: 29353235.
      Citations: 1     Fields:    Translation:Humans
    111. Kelley AR, Perry G, Bach SBH. Characterization of Proteins Present in Isolated Senile Plaques from Alzheimer's Diseased Brains by MALDI-TOF MS with MS/MS. ACS Chem Neurosci. 2018 04 18; 9(4):708-714. PMID: 29301075.
      Citations: 5     Fields:    
    112. Yan T, Wang L, Gao J, Siedlak SL, Huntley ML, Termsarasab P, Perry G, Chen SG, Wang X. Rab10 Phosphorylation is a Prominent Pathological Feature in Alzheimer's Disease. J Alzheimers Dis. 2018; 63(1):157-165. PMID: 29562525.
      Citations: 14     Fields:    Translation:HumansCells
    113. Perry G, Avila J, Moreira PI, Sorensen AA, Tabaton M. Preface. J Alzheimers Dis. 2018; 64(s1):S1. PMID: 29782320.
      Citations:    Fields:    Translation:Humans
    114. Smith MA, Bowen RL, Nguyen RQ, Perry G, Atwood CS, Rimm AA. Putative Gonadotropin-Releasing Hormone Agonist Therapy and Dementia: An Application of Medicare Hospitalization Claims Data. J Alzheimers Dis. 2018; 63(4):1269-1277. PMID: 29782310.
      Citations: 3     Fields:    Translation:Humans
    115. Perry G, Avila J, Tabaton M, Zhu X. Birth of JAD: 20 Years Later. J Alzheimers Dis. 2018; 62(3):901. PMID: 29562547.
      Citations:    Fields:    
    116. Perry G. Preface. Mini Rev Med Chem. 2018; 18(1):2. PMID: 29283061.
      Citations:    Fields:    
    117. Reale M, D'Angelo C, Costantini E, Di Nicola M, Yarla NS, Kamal MA, Salvador N, Perry G. Expression Profiling of Cytokine, Cholinergic Markers, and Amyloid-? Deposition in the APPSWE/PS1dE9 Mouse Model of Alzheimer's Disease Pathology. J Alzheimers Dis. 2018; 62(1):467-476. PMID: 29439355.
      Citations: 9     Fields:    Translation:HumansAnimals
    118. Manyevitch R, Protas M, Scarpiello S, Deliso M, Bass B, Nanajian A, Chang M, Thompson SM, Khoury N, Gonnella R, Trotz M, Moore DB, Harms E, Perry G, Clunes L, Ortiz A, Friedrich JO, Murray IVJ. Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer's Disease (AD): A Meta-Analysis of CSF Markers. Curr Alzheimer Res. 2018; 15(2):164-181. PMID: 28933272.
      Citations: 25     Fields:    Translation:HumansCells
    119. Frank L, Wesson Ashford J, Bayley PJ, Borson S, Buschke H, Cohen D, Cummings JL, Davies P, Dean M, Finkel SI, Hyer L, Perry G, Powers RE, Schmitt F. Genetic Risk of Alzheimer's Disease: Three Wishes Now That the Genie is Out of the Bottle. J Alzheimers Dis. 2018; 66(2):421-423. PMID: 30282369.
      Citations: 2     Fields:    Translation:Humans
    120. Vasquez V, Mitra J, Perry G, Rao KS, Hegde ML. An Inducible Alpha-Synuclein Expressing Neuronal Cell Line Model for Parkinson's Disease1. J Alzheimers Dis. 2018; 66(2):453-460. PMID: 30320583.
      Citations: 4     Fields:    Translation:HumansCells
    121. Iverson GL, Keene CD, Perry G, Castellani RJ. The Need to Separate Chronic Traumatic Encephalopathy Neuropathology from Clinical Features. J Alzheimers Dis. 2018; 61(1):17-28. PMID: 29103039.
      Citations: 21     Fields:    Translation:Humans
    122. Rodriguez RA, Chen LY, Plascencia-Villa G, Perry G. Thermodynamics of Amyloid-? Fibril Elongation: Atomistic Details of the Transition State. ACS Chem Neurosci. 2018 04 18; 9(4):783-789. PMID: 29239603.
      Citations: 13     Fields:    Translation:HumansCells
    123. Zabel M, Nackenoff A, Kirsch WM, Harrison FE, Perry G, Schrag M. Markers of oxidative damage to lipids, nucleic acids and proteins and antioxidant enzymes activities in Alzheimer's disease brain: A meta-analysis in human pathological specimens. Free Radic Biol Med. 2018 02 01; 115:351-360. PMID: 29253591.
      Citations: 33     Fields:    Translation:Humans
    124. Cornejo A, Aguilar Sandoval F, Caballero L, Machuca L, Mu?oz P, Caballero J, Perry G, Ardiles A, Areche C, Melo F. Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to ? sheet in tau protein linked to Alzheimer's disease. J Enzyme Inhib Med Chem. 2017 Dec; 32(1):945-953. PMID: 28701064.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    125. Henderson LE, Abdelmegeed MA, Yoo SH, Rhee SG, Zhu X, Smith MA, Nguyen RQ, Perry G, Song BJ. Enhanced Phosphorylation of Bax and Its Translocation into Mitochondria in the Brains of Individuals Affiliated with Alzheimer's Disease. Open Neurol J. 2017; 11:48-58. PMID: 29290835.
      Citations:    
    126. Wang W, Yin J, Ma X, Zhao F, Siedlak SL, Wang Z, Torres S, Fujioka H, Xu Y, Perry G, Zhu X. Inhibition of mitochondrial fragmentation protects against Alzheimer's disease in rodent model. Hum Mol Genet. 2017 11 01; 26(21):4118-4131. PMID: 28973308.
      Citations: 86     Fields:    Translation:AnimalsCells
    127. Mart?n-Maestro P, Gargini R, Garc?a E, Perry G, Avila J, Garc?a-Escudero V. Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease. Oxid Med Cell Longev. 2017; 2017:9302761. PMID: 29201274.
      Citations: 37     Fields:    Translation:HumansCells
    128. Wambo TO, Chen LY, Phelix C, Perry G. Affinity and path of binding xylopyranose unto E.?coli xylose permease. Biochem Biophys Res Commun. 2017 12 09; 494(1-2):202-206. PMID: 29032199.
      Citations: 6     Fields:    Translation:Cells
    129. Barh D, Garc?a-Solano ME, Tiwari S, Bhattacharya A, Jain N, Torres-Moreno D, Ferri B, Silva A, Azevedo V, Ghosh P, Blum K, Conesa-Zamora P, Perry G. BARHL1 Is Downregulated in Alzheimer's Disease and May Regulate Cognitive Functions through ESR1 and Multiple Pathways. Genes (Basel). 2017 Sep 28; 8(10). PMID: 28956815.
      Citations: 7     Fields:    
    130. Peluso I, Yarla NS, Ambra R, Pastore G, Perry G. MAPK signalling pathway in cancers: Olive products as cancer preventive and therapeutic agents. Semin Cancer Biol. 2019 06; 56:185-195. PMID: 28912082.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    131. Nunomura A, Lee HG, Zhu X, Perry G. Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders. Biochem Soc Trans. 2017 Oct 15; 45(5):1053-1066. PMID: 28778984.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    132. Hajipour MJ, Santoso MR, Rezaee F, Aghaverdi H, Mahmoudi M, Perry G. Advances in Alzheimer's Diagnosis and Therapy: The Implications of Nanotechnology. Trends Biotechnol. 2017 10; 35(10):937-953. PMID: 28666544.
      Citations: 37     Fields:    Translation:HumansAnimals
    133. Rodriguez RA, Chen LY, Plascencia-Villa G, Perry G. Elongation affinity, activation barrier, and stability of A?42 oligomers/fibrils in physiological saline. Biochem Biophys Res Commun. 2017 05 27; 487(2):444-449. PMID: 28427941.
      Citations: 6     Fields:    Translation:Cells
    134. Khalsa DS, Perry G. The Four Pillars of Alzheimer's Prevention. Cerebrum. 2017 Mar-Apr; 2017. PMID: 28698774.
      Citations:    
    135. Doens D, Valiente PA, Mfuh AM, X T Vo A, Tristan A, Carre?o L, Quijada M, Nguyen VT, Perry G, Larionov OV, Lleonart R, Fern?ndez PL. Identification of Inhibitors of CD36-Amyloid Beta Binding as Potential Agents for Alzheimer's Disease. ACS Chem Neurosci. 2017 06 21; 8(6):1232-1241. PMID: 28150942.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    136. Remington R, Shea TB, Perry G. Nutritional supplements and dementia. Clin Nutr. 2017 04; 36(2):613-614. PMID: 28153502.
      Citations:    Fields:    Translation:Humans
    137. Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. J Alzheimers Dis. 2017; 55(2):749-762. PMID: 27802219.
      Citations: 14     Fields:    Translation:HumansCells
    138. Nunomura A, Zhu X, Perry G. Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration. J Alzheimers Dis. 2017; 55(1):73-75. PMID: 27802241.
      Citations: 3     Fields:    Translation:HumansAnimals
    139. Mondrag?n-Rodr?guez S, Perry G, Pena-Ortega F, Williams S. Tau, Amyloid Beta and Deep Brain Stimulation: Aiming to Restore Cognitive Deficit in Alzheimer's Disease. Curr Alzheimer Res. 2017; 14(1):40-46. PMID: 27539594.
      Citations: 8     Fields:    Translation:AnimalsCells
    140. Putta S, Yarla NS, Peluso I, Tiwari DK, Reddy GV, Giri PV, Kumar N, Malla R, Rachel V, Bramhachari PV, Reddy D RS, Bade R, Mannarapu M, Barreto GE, Lu DY, Tarasov VV, Chubarev VN, Ribeiro FF, Scotti L, Scotti MT, Kamal MA, Ashraf GM, Aliev G, Perry G, Sarker SD, Rao CV, Bishayee A. Anthocyanins: Multi-Target Agents for Prevention and Therapy of Chronic Diseases. Curr Pharm Des. 2017; 23(41):6321-6346. PMID: 28741457.
      Citations: 10     Fields:    Translation:HumansAnimals
    141. Siedlak SL, Jiang Y, Huntley ML, Wang L, Gao J, Xie F, Liu J, Su B, Perry G, Wang X. TMEM230 Accumulation in Granulovacuolar Degeneration Bodies and Dystrophic Neurites of Alzheimer's Disease. J Alzheimers Dis. 2017; 58(4):1027-1033. PMID: 28527219.
      Citations: 5     Fields:    Translation:HumansCells
    142. Castellani RJ, Perry G. Dementia Pugilistica Revisited. J Alzheimers Dis. 2017; 60(4):1209-1221. PMID: 29036831.
      Citations: 9     Fields:    Translation:HumansAnimals
    143. Forero DA, Prada CF, Perry G. Functional and Genomic Features of Human Genes Mutated in Neuropsychiatric Disorders. Open Neurol J. 2016; 10:143-148. PMID: 27990183.
      Citations:    
    144. Castellani RJ, Mojica G, Perry G. The Role of the Iron Stain in Assessing Intracranial Hemorrhage. Open Neurol J. 2016; 10:136-142. PMID: 27857815.
      Citations:    
    145. Perry G. Promise from the Sea. Mar Drugs. 2016 Oct 09; 14(10). PMID: 27735831.
      Citations: 1     Fields:    Translation:HumansAnimals
    146. Kelley AR, Perry G, Bethea C, Castellani RJ, Bach SB. Molecular Mapping Alzheimer's Disease: MALDI Imaging of Formalin-fixed, Paraffin-embedded Human Hippocampal Tissue. Open Neurol J. 2016; 10:88-98. PMID: 27843502.
      Citations:    
    147. Aryan N, Betts-Obregon BS, Perry G, Tsin AT. Oxidative Stress Induces Senescence in Cultured RPE Cells. Open Neurol J. 2016; 10:83-7. PMID: 27651846.
      Citations:    
    148. Correia SC, Perry G, Moreira PI. Mitochondrial traffic jams in Alzheimer's disease - pinpointing the roadblocks. Biochim Biophys Acta. 2016 10; 1862(10):1909-17. PMID: 27460705.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    149. Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, Perry G, Odetti P, Arancio O, Tamagno E, Tabaton M. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. 2016 10; 15(5):914-23. PMID: 27406053.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    150. Herrera L, Stephens DE, D'Avila A, George KG, Arman H, Zhang Y, Perry G, Lleonart R, Larionov OV, Fern?ndez PL. Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles. Org Biomol Chem. 2016 Aug 07; 14(29):7053-60. PMID: 27376396.
      Citations: 5     Fields:    Translation:AnimalsCells
    151. Pistollato F, Ohayon EL, Lam A, Langley GR, Novak TJ, Pamies D, Perry G, Trushina E, Williams RS, Roher AE, Hartung T, Harnad S, Barnard N, Morris MC, Lai MC, Merkley R, Chandrasekera PC. Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding priorities. Oncotarget. 2016 Jun 28; 7(26):38999-39016. PMID: 27229915.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    152. Hofer T, Perry G. Nucleic acid oxidative damage in Alzheimer's disease-explained by the hepcidin-ferroportin neuronal iron overload hypothesis? J Trace Elem Med Biol. 2016 Dec; 38:1-9. PMID: 27329321.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    153. Plascencia-Villa G, Ponce A, Collingwood JF, Arellano-Jim?nez MJ, Zhu X, Rogers JT, Betancourt I, Jos?-Yacam?n M, Perry G. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Sci Rep. 2016 04 28; 6:24873. PMID: 27121137.
      Citations: 48     Fields:    Translation:Humans
    154. Forero DA, Gonz?lez-Giraldo Y, L?pez-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Meta-analysis of Telomere Length in Alzheimer's Disease. J Gerontol A Biol Sci Med Sci. 2016 08; 71(8):1069-73. PMID: 27091133.
      Citations: 78     Fields:    Translation:HumansCells
    155. Ontiveros-Torres M?, Labra-Barrios ML, D?az-Cintra S, Aguilar-V?zquez AR, Moreno-Campuzano S, Flores-Rodr?guez P, Luna-Herrera C, Mena R, Perry G, Flor?n-Gardu?o B, Luna-Mu?oz J, Luna-Arias JP. Fibrillar Amyloid-? Accumulation Triggers an Inflammatory Mechanism Leading to Hyperphosphorylation of the Carboxyl-Terminal End of Tau Polypeptide in the Hippocampal Formation of the 3?Tg-AD Transgenic Mouse. J Alzheimers Dis. 2016 03 22; 52(1):243-69. PMID: 27031470.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    156. Wang C, Zhang F, Jiang S, Siedlak SL, Shen L, Perry G, Wang X, Tang B, Zhu X. Estrogen receptor-a is localized to neurofibrillary tangles in Alzheimer's disease. Sci Rep. 2016 Feb 03; 6:20352. PMID: 26837465.
      Citations: 21     Fields:    Translation:HumansCells
    157. Yu L, Rodriguez RA, Chen LL, Chen LY, Perry G, McHardy SF, Yeh CK. 1,3-propanediol binds deep inside the channel to inhibit water permeation through aquaporins. Protein Sci. 2016 Feb; 25(2):433-41. PMID: 26481430.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    158. Calder?n-Garcidue?as L, Reynoso-Robles R, Vargas-Mart?nez J, G?mez-Maqueo-Chew A, P?rez-Guill? B, Mukherjee PS, Torres-Jard?n R, Perry G, G?nzalez-Maciel A. Prefrontal white matter pathology in air pollution exposed Mexico City young urbanites and their potential impact on neurovascular unit dysfunction and the development of Alzheimer's disease. Environ Res. 2016 Apr; 146:404-17. PMID: 26829765.
      Citations: 59     Fields:    Translation:HumansAnimalsPHPublic Health
    159. Forero DA, Gonz?lez-Giraldo Y, L?pez-Quintero C, Castro-Vega LJ, Barreto GE, Perry G. Telomere length in Parkinson's disease: A meta-analysis. Exp Gerontol. 2016 Mar; 75:53-5. PMID: 26772888.
      Citations: 25     Fields:    Translation:HumansCells
    160. Kelley AR, Perry G, Castellani RJ, Bach SB. Laser-Induced In-Source Decay Applied to the Determination of Amyloid-Beta in Alzheimer's Brains. ACS Chem Neurosci. 2016 Mar 16; 7(3):261-8. PMID: 26720297.
      Citations: 7     Fields:    Translation:Humans
    161. Forero DA, Wonkam A, Wang W, Laissue P, L?pez-Correa C, Fern?ndez-L?pez JC, Mugasimangalam R, Perry G. Current needs for human and medical genomics research infrastructure in low and middle income countries. J Med Genet. 2016 07; 53(7):438-40. PMID: 26740506.
      Citations: 7     Fields:    Translation:Humans
    162. Itzhaki RF, Lathe R, Balin BJ, Ball MJ, Bearer EL, Braak H, Bullido MJ, Carter C, Clerici M, Cosby SL, Del Tredici K, Field H, Fulop T, Grassi C, Griffin WS, Haas J, Hudson AP, Kamer AR, Kell DB, Licastro F, Letenneur L, L?vheim H, Mancuso R, Miklossy J, Otth C, Palamara AT, Perry G, Preston C, Pretorius E, Strandberg T, Tabet N, Taylor-Robinson SD, Whittum-Hudson JA. Microbes and Alzheimer's Disease. J Alzheimers Dis. 2016; 51(4):979-84. PMID: 26967229.
      Citations: 216     Fields:    Translation:HumansAnimals
    163. Mart?n-Maestro P, Gargini R, Perry G, Avila J, Garc?a-Escudero V. PARK2 enhancement is able to compensate mitophagy alterations found in sporadic Alzheimer's disease. Hum Mol Genet. 2016 Feb 15; 25(4):792-806. PMID: 26721933.
      Citations: 81     Fields:    Translation:HumansCells
    164. Singh SK, Srivastav S, Yadav AK, Srikrishna S, Perry G. Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting A? by Using Several Synthetic and Herbal Compounds. Oxid Med Cell Longev. 2016; 2016:7361613. PMID: 27034741.
      Citations: 53     Fields:    Translation:HumansAnimals
    165. Sharoar MG, Shi Q, Ge Y, He W, Hu X, Perry G, Zhu X, Yan R. Dysfunctional tubular endoplasmic reticulum constitutes a pathological feature of Alzheimer's disease. Mol Psychiatry. 2016 09; 21(9):1263-71. PMID: 26619807.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    166. Jiang Z, Wang W, Perry G, Zhu X, Wang X. Mitochondrial dynamic abnormalities in amyotrophic lateral sclerosis. Transl Neurodegener. 2015; 4:14. PMID: 26225210.
      Citations: 16     Fields:    
    167. Calder?n-Garcidue?as L, Franco-Lira M, D'Angiulli A, Rodr?guez-D?az J, Blaurock-Busch E, Busch Y, Chao CK, Thompson C, Mukherjee PS, Torres-Jard?n R, Perry G. Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease. Environ Res. 2015 Jul; 140:579-92. PMID: 26037109.
      Citations: 33     Fields:    Translation:Humans
    168. Castellani RJ, Perry G, Iverson GL. Chronic effects of mild neurotrauma: putting the cart before the horse? J Neuropathol Exp Neurol. 2015 Jun; 74(6):493-9. PMID: 25933385.
      Citations: 13     Fields:    Translation:Humans
    169. Zhang F, Wang W, Siedlak SL, Liu Y, Liu J, Jiang K, Perry G, Zhu X, Wang X. Miro1 deficiency in amyotrophic lateral sclerosis. Front Aging Neurosci. 2015; 7:100. PMID: 26074815.
      Citations:    
    170. Zhang F, Su B, Wang C, Siedlak SL, Mondragon-Rodriguez S, Lee HG, Wang X, Perry G, Zhu X. Posttranslational modifications of a-tubulin in alzheimer disease. Transl Neurodegener. 2015; 4:9. PMID: 26029362.
      Citations: 44     Fields:    
    171. Gerenu G, Liu K, Chojnacki JE, Saathoff JM, Mart?nez-Mart?n P, Perry G, Zhu X, Lee HG, Zhang S. Curcumin/melatonin hybrid 5-(4-hydroxy-phenyl)-3-oxo-pentanoic acid [2-(5-methoxy-1H-indol-3-yl)-ethyl]-amide ameliorates AD-like pathology in the APP/PS1 mouse model. ACS Chem Neurosci. 2015 Aug 19; 6(8):1393-1399. PMID: 25893520.
      Citations: 17     Fields:    Translation:AnimalsCells
    172. Avila J, Perry G, Strange BA, Hernandez F. Alternative neural circuitry that might be impaired in the development of Alzheimer disease. Front Neurosci. 2015; 9:145. PMID: 25954151.
      Citations:    
    173. Rodriguez AR, Plascencia-Villa G, Witt CM, Yu JJ, Jos?-Yacam?n M, Chambers JP, Perry G, Guentzel MN, Arulanandam BP. Chlamydia pneumoniae promotes dysfunction of pancreatic beta cells. Cell Immunol. 2015 Jun; 295(2):83-91. PMID: 25863744.
      Citations: 4     Fields:    Translation:AnimalsCells
    174. Pelcovits A, Marriotti R, Heath J, Perry G, Castellani RJ. Simultaneous onset of Alzheimer's disease in a husband and wife in their mid-fifties: what do we really know about environmental factors? Open Neurol J. 2015; 9:1-3. PMID: 25932054.
      Citations:    
    175. Carvalho C, Correia SC, Perry G, Castellani RJ, Moreira PI. Cerebrovascular and mitochondrial abnormalities in Alzheimer's disease: a brief overview. J Neural Transm (Vienna). 2016 Feb; 123(2):107-11. PMID: 25608860.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    176. Petersen RB, Lissemore FM, Appleby B, Aggarwal N, Boyatzis R, Casadesus G, Cummings J, Jack A, Perry G, Safar J, Sajatovic M, Surewicz WK, Wang Y, Whitehouse P, Lerner A. From Neurodegeneration to Brain Health: An Integrated Approach. J Alzheimers Dis. 2015; 46(1):271-83. PMID: 25720413.
      Citations: 1     Fields:    Translation:HumansAnimals
    177. Spremo-Potparevic B, Bajic V, Perry G, Zivkovic L. Alterations of the X Chromosome in Lymphocytes of Alzheimer's Disease Patients. Curr Alzheimer Res. 2015; 12(10):990-6. PMID: 26502819.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    178. Bowen RL, Perry G, Xiong C, Smith MA, Atwood CS. A clinical study of lupron depot in the treatment of women with Alzheimer's disease: preservation of cognitive function in patients taking an acetylcholinesterase inhibitor and treated with high dose lupron over 48 weeks. J Alzheimers Dis. 2015; 44(2):549-60. PMID: 25310993.
      Citations: 22     Fields:    Translation:Humans
    179. Luna-Mu?oz J, Perry G, Guevara J. Ra?l Mena: 1953-2014. J Alzheimers Dis. 2015; 45(2):325-7. PMID: 25757649.
      Citations:    Fields:    Translation:Humans
    180. Perry G. Two hundred treasured issues! J Alzheimers Dis. 2015; 44(3):725. PMID: 25663057.
      Citations:    Fields:    Translation:Humans
    181. Forero DA, V?lez-van-Meerbeke A, Deshpande SN, Nicolini H, Perry G. Neuropsychiatric genetics in developing countries: Current challenges. World J Psychiatry. 2014 Dec 22; 4(4):69-71. PMID: 25540721.
      Citations:    
    182. Fornicola W, Pelcovits A, Li BX, Heath J, Perry G, Castellani RJ. Alzheimer Disease Pathology in Middle Age Reveals a Spatial-Temporal Disconnect Between Amyloid-? and Phosphorylated Tau. Open Neurol J. 2014; 8:22-6. PMID: 25628768.
      Citations:    
    183. Habibi L, Perry G, Mahmoudi M. Global warming and neurodegenerative disorders: speculations on their linkage. Bioimpacts. 2014; 4(4):167-70. PMID: 25671171.
      Citations:    
    184. Xia J, Rocke DM, Perry G, Ray M. Differential network analyses of Alzheimer's disease identify early events in Alzheimer's disease pathology. Int J Alzheimers Dis. 2014; 2014:721453. PMID: 25147748.
      Citations:    
    185. Rodrigues R, Petersen RB, Perry G. Parallels between major depressive disorder and Alzheimer's disease: role of oxidative stress and genetic vulnerability. Cell Mol Neurobiol. 2014 Oct; 34(7):925-49. PMID: 24927694.
      Citations: 27     Fields:    Translation:Humans
    186. Blair JA, Siedlak SL, Wolfram JA, Nunomura A, Castellani RJ, Ferreira ST, Klein WL, Wang Y, Casadesus G, Smith MA, Perry G, Zhu X, Lee HG. Accumulation of intraneuronal amyloid-? is common in normal brain. Curr Alzheimer Res. 2014 May; 11(4):317-24. PMID: 24597504.
      Citations: 8     Fields:    Translation:Humans
    187. Bonda DJ, Wang X, Lee HG, Smith MA, Perry G, Zhu X. Neuronal failure in Alzheimer's disease: a view through the oxidative stress looking-glass. Neurosci Bull. 2014 Apr; 30(2):243-52. PMID: 24733654.
      Citations: 48     Fields:    Translation:HumansCells
    188. Johnston JM, Hu WT, Fardo DW, Greco SJ, Perry G, Montine TJ, Trojanowski JQ, Shaw LM, Ashford JW, Tezapsidis N. Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential. Curr Alzheimer Res. 2014 Feb; 11(2):165-74. PMID: 24359504.
      Citations: 27     Fields:    Translation:Humans
    189. Mondrag?n-Rodr?guez S, Perry G, Luna-Mu?oz J, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein at sites Ser(396-404) is one of the earliest events in Alzheimer's disease and Down syndrome. Neuropathol Appl Neurobiol. 2014 Feb; 40(2):121-35. PMID: 24033439.
      Citations: 117     Fields:    Translation:HumansCells
    190. Perry G, Castellani R. Plaques and tangles: birthmarks of the aging soul. Preface. Biochem Pharmacol. 2014 Apr 15; 88(4):423-5. PMID: 24486570.
      Citations:    Fields:    Translation:HumansCells
    191. Castellani RJ, Perry G. The complexities of the pathology-pathogenesis relationship in Alzheimer disease. Biochem Pharmacol. 2014 Apr 15; 88(4):671-6. PMID: 24447936.
      Citations: 36     Fields:    Translation:Humans
    192. Rosen AC, Ashford JW, Perry G. Ethics review as a catalyst for progress. J Alzheimers Dis. 2014; 40(2):233-5. PMID: 24583402.
      Citations:    Fields:    Translation:HumansAnimals
    193. Fawver JN, Ghiwot Y, Koola C, Carrera W, Rodriguez-Rivera J, Hernandez C, Dineley KT, Kong Y, Li J, Jhamandas J, Perry G, Murray IV. Islet amyloid polypeptide (IAPP): a second amyloid in Alzheimer's disease. Curr Alzheimer Res. 2014; 11(10):928-40. PMID: 25387341.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    194. Brinkley WR, Perry G. Lester (Skip) Binder (1949-2013): in the beginning was tau. J Alzheimers Dis. 2014; 40 Suppl 1:S5. PMID: 24867914.
      Citations:    Fields:    Translation:HumansAnimals
    195. Hoffmann C, Zimmermann A, Hinney A, Volckmar AL, Jarrett HW, Fromme T, Klingenspor M. A novel SP1/SP3 dependent intronic enhancer governing transcription of the UCP3 gene in brown adipocytes. PLoS One. 2013; 8(12):e83426. PMID: 24391766.
      Citations: 12     Fields:    Translation:AnimalsCells
    196. Bharadwaj PR, Bates KA, Porter T, Teimouri E, Perry G, Steele JW, Gandy S, Groth D, Martins RN, Verdile G. Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases. Transl Psychiatry. 2013 Dec 03; 3:e332. PMID: 24301650.
      Citations: 30     Fields:    Translation:HumansAnimals
    197. Jarero-Basulto JJ, Luna-Mu?oz J, Mena R, Kristofikova Z, Ripova D, Perry G, Binder LI, Garcia-Sierra F. Proteolytic cleavage of polymeric tau protein by caspase-3: implications for Alzheimer disease. J Neuropathol Exp Neurol. 2013 Dec; 72(12):1145-61. PMID: 24226268.
      Citations: 23     Fields:    Translation:HumansCells
    198. Fujioka H, Phelix CF, Friedland RP, Zhu X, Perry EA, Castellani RJ, Perry G. Apolipoprotein E4 prevents growth of malaria at the intraerythrocyte stage: implications for differences in racial susceptibility to Alzheimer's disease. J Health Care Poor Underserved. 2013 Nov; 24(4 Suppl):70-8. PMID: 24241262.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    199. Wang X, Wang W, Li L, Perry G, Lee HG, Zhu X. Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochim Biophys Acta. 2014 Aug; 1842(8):1240-7. PMID: 24189435.
      Citations: 466     Fields:    Translation:HumansAnimalsCells
    200. Paley EL, Perry G, Sokolova O. Tryptamine induces axonopathy and mitochondriopathy mimicking neurodegenerative diseases via tryptophanyl-tRNA deficiency. Curr Alzheimer Res. 2013 Nov; 10(9):987-1004. PMID: 24117115.
      Citations: 6     Fields:    Translation:AnimalsCells
    201. Williams WM, Torres S, Siedlak SL, Castellani RJ, Perry G, Smith MA, Zhu X. Antimicrobial peptide ?-defensin-1 expression is upregulated in Alzheimer's brain. J Neuroinflammation. 2013 Oct 18; 10:127. PMID: 24139179.
      Citations: 22     Fields:    Translation:HumansCells
    202. Correia SC, Perry G, Castellani R, Moreira PI. Is exercise-in-a-bottle likely to proffer new insights into Alzheimer's disease? J Neurochem. 2013 Oct; 127(1):4-6. PMID: 24074055.
      Citations: 1     Fields:    Translation:HumansAnimals
    203. Li W, Murthy AK, Lanka GK, Chetty SL, Yu JJ, Chambers JP, Zhong G, Forsthuber TG, Guentzel MN, Arulanandam BP. A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice. Vaccine. 2013 Nov 19; 31(48):5722-8. PMID: 24096029.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    204. Bonda DJ, Stone JG, Torres SL, Siedlak SL, Perry G, Kryscio R, Jicha G, Casadesus G, Smith MA, Zhu X, Lee HG. Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance. J Neurochem. 2014 Jan; 128(1):162-72. PMID: 23895348.
      Citations: 57     Fields:    Translation:HumansCells
    205. Schrag M, Mueller C, Zabel M, Crofton A, Kirsch WM, Ghribi O, Squitti R, Perry G. Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis. Neurobiol Dis. 2013 Nov; 59:100-10. PMID: 23867235.
      Citations: 107     Fields:    Translation:HumansAnimalsCells
    206. Mondrag?n-Rodr?guez S, Perry G, Zhu X, Moreira PI, Acevedo-Aquino MC, Williams S. Phosphorylation of tau protein as the link between oxidative stress, mitochondrial dysfunction, and connectivity failure: implications for Alzheimer's disease. Oxid Med Cell Longev. 2013; 2013:940603. PMID: 23936615.
      Citations: 66     Fields:    Translation:HumansCells
    207. Garc?a-Escudero V, Mart?n-Maestro P, Perry G, Avila J. Deconstructing mitochondrial dysfunction in Alzheimer disease. Oxid Med Cell Longev. 2013; 2013:162152. PMID: 23840916.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    208. Perry EA, Castellani RJ, Moreira PI, Nunomura A, Lui Q, Harris PL, Sayre LM, Szweda PA, Szweda LI, Zhu X, Smith MA, Perry G. Neurofilaments are the major neuronal target of hydroxynonenal-mediated protein cross-links. Free Radic Res. 2013 Jul; 47(6-7):507-10. PMID: 23566300.
      Citations: 9     Fields:    Translation:Animals
    209. Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G, Smith MA, Moreira PI. Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Curr Alzheimer Res. 2013 May 01; 10(4):406-19. PMID: 23061885.
      Citations: 40     Fields:    Translation:AnimalsCells
    210. Perry G. Reply: comments on "The effects of vaccination on serum hormone concentrations and conception rates in synchronized naive beef heifers". Theriogenology. 2013 Jul 01; 80(1):71. PMID: 23628363.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    211. Haldar S, Beveridge 'J, Wong J, Singh A, Galimberti D, Borroni B, Zhu X, Blevins J, Greenlee J, Perry G, Mukhopadhyay CK, Schmotzer C, Singh N. A low-molecular-weight ferroxidase is increased in the CSF of sCJD cases: CSF ferroxidase and transferrin as diagnostic biomarkers for sCJD. Antioxid Redox Signal. 2013 Nov 10; 19(14):1662-75. PMID: 23379482.
      Citations: 9     Fields:    Translation:Humans
    212. Dur?n-Gonz?lez J, Michi ED, Elorza B, Perez-C?rdova MG, Pacheco-Otalora LF, Touhami A, Paulson P, Perry G, Murray IV, Colom LV. Amyloid ? peptides modify the expression of antioxidant repair enzymes and a potassium channel in the septohippocampal system. Neurobiol Aging. 2013 Aug; 34(8):2071-6. PMID: 23473707.
      Citations: 13     Fields:    Translation:Animals
    213. Zivkovic L, Spremo-Potparevic B, Siedlak SL, Perry G, Pleca?-Solarovic B, Milicevic Z, Bajic VP. DNA damage in Alzheimer disease lymphocytes and its relation to premature centromere division. Neurodegener Dis. 2013; 12(3):156-63. PMID: 23406622.
      Citations: 6     Fields:    Translation:HumansCells
    214. Perry G, Zhu X, Smith MA, Sorensen A, Avila J. Preface. Alzheimer's disease: advances for a new century. J Alzheimers Dis. 2013; 33 Suppl 1:S1. PMID: 23397602.
      Citations: 2     Fields:    Translation:Humans
    215. Colom LV, Perry G, Kuljis RO. Tackling the elusive challenges relevant to conquering the 100-plus year old problem of Alzheimer's disease. Curr Alzheimer Res. 2013 Jan; 10(1):108-16. PMID: 23368433.
      Citations: 4     Fields:    Translation:Humans
    216. Perry G. The largest unmet market: chronic diseases of aging. Mini Rev Med Chem. 2013 Jan; 13(1):1. PMID: 23447815.
      Citations:    Fields:    Translation:Humans
    217. Zhu X, Perry G, Smith MA, Wang X. Abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Alzheimers Dis. 2013; 33 Suppl 1:S253-62. PMID: 22531428.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    218. Hou L, Lee HG, Han F, Tedesco JM, Perry G, Smith MA, Zagorski MG. Modification of amyloid-?1-42 fibril structure by methionine-35 oxidation. J Alzheimers Dis. 2013; 37(1):9-18. PMID: 23719512.
      Citations: 12     Fields:    Translation:HumansCells
    219. Coskuner O, Wise-Scira O, Perry G, Kitahara T. The structures of the E22? mutant-type amyloid-? alloforms and the impact of E22? mutation on the structures of the wild-type amyloid-? alloforms. ACS Chem Neurosci. 2013 Feb 20; 4(2):310-20. PMID: 23421682.
      Citations: 14     Fields:    Translation:HumansCells
    220. Santos RX, Correia SC, Zhu X, Smith MA, Moreira PI, Castellani RJ, Nunomura A, Perry G. Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease. Antioxid Redox Signal. 2013 Jun 20; 18(18):2444-57. PMID: 23216311.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    221. Greco SJ, Hamzelou A, Johnston JM, Richardson S, Smith MA, Perry G, Ashford JW, Tezapsidis N. Isotyping the human TOMM40 variable-length polymorphism by gene amplification and restriction digest. Curr Alzheimer Res. 2012 Dec; 9(10):1168-73. PMID: 22950840.
      Citations:    Fields:    Translation:Humans
    222. Candeias E, Duarte AI, Carvalho C, Correia SC, Cardoso S, Santos RX, Pl?cido AI, Perry G, Moreira PI. The impairment of insulin signaling in Alzheimer's disease. IUBMB Life. 2012 Dec; 64(12):951-7. PMID: 23129399.
      Citations: 28     Fields:    Translation:HumansCells
    223. Castellani RJ, Perry G. Pathogenesis and disease-modifying therapy in Alzheimer's disease: the flat line of progress. Arch Med Res. 2012 Nov; 43(8):694-8. PMID: 23085451.
      Citations: 36     Fields:    Translation:HumansCells
    224. Miklossy J, Donta S, Mueller K, Nolte O, Perry G. Chronic or late lyme neuroborreliosis: present and future. Open Neurol J. 2012; 6:78. PMID: 23091567.
      Citations:    
    225. Morelli L, Perry G, Tagliavini F. The contribution of the amyloid hypothesis to the understanding of Alzheimer's disease: a critical overview. Int J Alzheimers Dis. 2012; 2012:709613. PMID: 22970405.
      Citations:    
    226. Piccini A, Borghi R, Guglielmotto M, Tamagno E, Cirmena G, Garuti A, Pollero V, Cammarata S, Fornaro M, Messa M, Colombo L, Salmona M, Perry G, Tabaton M. ?-amyloid 1-42 induces physiological transcriptional regulation of BACE1. J Neurochem. 2012 Sep; 122(5):1023-31. PMID: 22708832.
      Citations: 11     Fields:    Translation:HumansCells
    227. Mondrag?n-Rodr?guez S, Perry G, Zhu X, Moreira PI, Williams S. Glycogen synthase kinase 3: a point of integration in Alzheimer's disease and a therapeutic target? Int J Alzheimers Dis. 2012; 2012:276803. PMID: 22779025.
      Citations:    
    228. Wise-Scira O, Xu L, Perry G, Coskuner O. Structures and free energy landscapes of aqueous zinc(II)-bound amyloid-?(1-40) and zinc(II)-bound amyloid-?(1-42) with dynamics. J Biol Inorg Chem. 2012 Aug; 17(6):927-38. PMID: 22674434.
      Citations: 15     Fields:    Translation:Cells
    229. Nunomura A, Moreira PI, Castellani RJ, Lee HG, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in aging and neurodegenerative disorders. Neurotox Res. 2012 Oct; 22(3):231-48. PMID: 22669748.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    230. Rodrigues R, Smith MA, Wang X, Perry G, Lee HG, Zhu X, Petersen RB. Molecular neuropathogenesis of Alzheimer's disease: an interaction model stressing the central role of oxidative stress. Future Neurol. 2012 May; 7(3):287-305. PMID: 23086377.
      Citations:    
    231. Liu G, Men P, Zhu X, Perry G. Iron chelation and nanoparticle target delivery in the development of new multifunctional disease-modifying drugs for Alzheimer's disease. Ther Deliv. 2012 May; 3(5):571-4. PMID: 22834400.
      Citations: 1     Fields:    Translation:HumansAnimals
    232. Williams WM, Castellani RJ, Weinberg A, Perry G, Smith MA. Do ?-defensins and other antimicrobial peptides play a role in neuroimmune function and neurodegeneration? ScientificWorldJournal. 2012; 2012:905785. PMID: 22606066.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    233. Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, Al-Younes HM, Al-Zeer MA, Albert ML, Albin RL, Alegre-Abarrategui J, Aleo MF, Alirezaei M, Almasan A, Almonte-Becerril M, Amano A, Amaravadi R, Amarnath S, Amer AO, Andrieu-Abadie N, Anantharam V, Ann DK, Anoopkumar-Dukie S, Aoki H, Apostolova N, Arancia G, Aris JP, Asanuma K, Asare NY, Ashida H, Askanas V, Askew DS, Auberger P, Baba M, Backues SK, Baehrecke EH, Bahr BA, Bai XY, Bailly Y, Baiocchi R, Baldini G, Balduini W, Ballabio A, Bamber BA, Bampton ET, B?nhegyi G, Bartholomew CR, Bassham DC, Bast RC, Batoko H, Bay BH, Beau I, B?chet DM, Begley TJ, Behl C, Behrends C, Bekri S, Bellaire B, Bendall LJ, Benetti L, Berliocchi L, Bernardi H, Bernassola F, Besteiro S, Bhatia-Kissova I, Bi X, Biard-Piechaczyk M, Blum JS, Boise LH, Bonaldo P, Boone DL, Bornhauser BC, Bortoluci KR, Bossis I, Bost F, Bourquin JP, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady NR, Brancolini C, Brech A, Brenman JE, Brennand A, Bresnick EH, Brest P, Bridges D, Bristol ML, Brookes PS, Brown EJ, Brumell JH, Brunetti-Pierri N, Brunk UT, Bulman DE, Bultman SJ, Bultynck G, Burbulla LF, Bursch W, Butchar JP, Buzgariu W, Bydlowski SP, Cadwell K, Cahov? M, Cai D, Cai J, Cai Q, Calabretta B, Calvo-Garrido J, Camougrand N, Campanella M, Campos-Salinas J, Candi E, Cao L, Caplan AB, Carding SR, Cardoso SM, Carew JS, Carlin CR, Carmignac V, Carneiro LA, Carra S, Caruso RA, Casari G, Casas C, Castino R, Cebollero E, Cecconi F, Celli J, Chaachouay H, Chae HJ, Chai CY, Chan DC, Chan EY, Chang RC, Che CM, Chen CC, Chen GC, Chen GQ, Chen M, Chen Q, Chen SS, Chen W, Chen X, Chen X, Chen X, Chen YG, Chen Y, Chen Y, Chen YJ, Chen Z, Cheng A, Cheng CH, Cheng Y, Cheong H, Cheong JH, Cherry S, Chess-Williams R, Cheung ZH, Chevet E, Chiang HL, Chiarelli R, Chiba T, Chin LS, Chiou SH, Chisari FV, Cho CH, Cho DH, Choi AM, Choi D, Choi KS, Choi ME, Chouaib S, Choubey D, Choubey V, Chu CT, Chuang TH, Chueh SH, Chun T, Chwae YJ, Chye ML, Ciarcia R, Ciriolo MR, Clague MJ, Clark RS, Clarke PG, Clarke R, Codogno P, Coller HA, Colombo MI, Comincini S, Condello M, Condorelli F, Cookson MR, Coombs GH, Coppens I, Corbalan R, Cossart P, Costelli P, Costes S, Coto-Montes A, Couve E, Coxon FP, Cregg JM, Crespo JL, Cronj? MJ, Cuervo AM, Cullen JJ, Czaja MJ, D'Amelio M, Darfeuille-Michaud A, Davids LM, Davies FE, De Felici M, de Groot JF, de Haan CA, De Martino L, De Milito A, De Tata V, Debnath J, Degterev A, Dehay B, Delbridge LM, Demarchi F, Deng YZ, Dengjel J, Dent P, Denton D, Deretic V, Desai SD, Devenish RJ, Di Gioacchino M, Di Paolo G, Di Pietro C, D?az-Araya G, D?az-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dikic I, Dinesh-Kumar SP, Ding WX, Distelhorst CW, Diwan A, Djavaheri-Mergny M, Dokudovskaya S, Dong Z, Dorsey FC, Dosenko V, Dowling JJ, Doxsey S, Dreux M, Drew ME, Duan Q, Duchosal MA, Duff K, Dugail I, Durbeej M, Duszenko M, Edelstein CL, Edinger AL, Egea G, Eichinger L, Eissa NT, Ekmekcioglu S, El-Deiry WS, Elazar Z, Elgendy M, Ellerby LM, Eng KE, Engelbrecht AM, Engelender S, Erenpreisa J, Escalante R, Esclatine A, Eskelinen EL, Espert L, Espina V, Fan H, Fan J, Fan QW, Fan Z, Fang S, Fang Y, Fanto M, Fanzani A, Farkas T, Farr? JC, Faure M, Fechheimer M, Feng CG, Feng J, Feng Q, Feng Y, F?s?s L, Feuer R, Figueiredo-Pereira ME, Fimia GM, Fingar DC, Finkbeiner S, Finkel T, Finley KD, Fiorito F, Fisher EA, Fisher PB, Flajolet M, Florez-McClure ML, Florio S, Fon EA, Fornai F, Fortunato F, Fotedar R, Fowler DH, Fox HS, Franco R, Frankel LB, Fransen M, Fuentes JM, Fueyo J, Fujii J, Fujisaki K, Fujita E, Fukuda M, Furukawa RH, Gaestel M, Gailly P, Gajewska M, Galliot B, Galy V, Ganesh S, Ganetzky B, Ganley IG, Gao FB, Gao GF, Gao J, Garcia L, Garcia-Manero G, Garcia-Marcos M, Garmyn M, Gartel AL, Gatti E, Gautel M, Gawriluk TR, Gegg ME, Geng J, Germain M, Gestwicki JE, Gewirtz DA, Ghavami S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 2012 Apr; 8(4):445-544. PMID: 22966490.
      Citations: 1810     Fields:    Translation:HumansAnimals
    234. Castellani RJ, Moreira PI, Perry G, Zhu X. The role of iron as a mediator of oxidative stress in Alzheimer disease. Biofactors. 2012 Mar-Apr; 38(2):133-8. PMID: 22447715.
      Citations: 28     Fields:    Translation:HumansAnimals
    235. Mondrag?n-Rodr?guez S, Perry G, Zhu X, Boehm J. Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy. Int J Alzheimers Dis. 2012; 2012:630182. PMID: 22482074.
      Citations:    
    236. Nunomura A, Tamaoki T, Motohashi N, Nakamura M, McKeel DW, Tabaton M, Lee HG, Smith MA, Perry G, Zhu X. The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons. J Neuropathol Exp Neurol. 2012 Mar; 71(3):233-41. PMID: 22318126.
      Citations: 48     Fields:    Translation:HumansCells
    237. Perry GH, Xue Y, Smith RS, Meyer WK, Caliskan M, Yanez-Cuna O, Lee AS, Guti?rrez-Arcelus M, Ober C, Hollox EJ, Tyler-Smith C, Lee C. Evolutionary genetics of the human Rh blood group system. Hum Genet. 2012 Jul; 131(7):1205-16. PMID: 22367406.
      Citations: 6     Fields:    Translation:HumansCells
    238. Reed-Cossairt A, Zhu X, Lee HG, Reed C, Perry G, Petersen RB. Alzheimer's disease and vascular deficiency: lessons from imaging studies and down syndrome. Curr Gerontol Geriatr Res. 2012; 2012:929734. PMID: 22400025.
      Citations:    
    239. Bonda DJ, Liu G, Men P, Perry G, Smith MA, Zhu X. Nanoparticle delivery of transition-metal chelators to the brain: Oxidative stress will never see it coming! CNS Neurol Disord Drug Targets. 2012 Feb; 11(1):81-5. PMID: 22229318.
      Citations: 9     Fields:    Translation:HumansAnimals
    240. Santos RX, Correia SC, Zhu X, Lee HG, Petersen RB, Nunomura A, Smith MA, Perry G, Moreira PI. Nuclear and mitochondrial DNA oxidation in Alzheimer's disease. Free Radic Res. 2012 Apr; 46(4):565-76. PMID: 22149654.
      Citations: 17     Fields:    Translation:HumansCells
    241. Zhu X, Castellani RJ, Ziats NP, Petersen RB, Gon Lee H, Perry G. Mark A. Smith: neurocytochemistry innovator. J Neurochem. 2012 Mar; 120(6):1139-40. PMID: 22268813.
      Citations:    Fields:    Translation:HumansCells
    242. Wang X, Yan MH, Fujioka H, Liu J, Wilson-Delfosse A, Chen SG, Perry G, Casadesus G, Zhu X. LRRK2 regulates mitochondrial dynamics and function through direct interaction with DLP1. Hum Mol Genet. 2012 May 01; 21(9):1931-44. PMID: 22228096.
      Citations: 224     Fields:    Translation:HumansAnimalsCells
    243. Perry G, Phelix CF, Nunomura A, Colom LV, Castellani RJ, Petersen RB, Lee HG, Zhu X. Untangling the vascular web from Alzheimer disease and oxidative stress. Can J Neurol Sci. 2012 Jan; 39(1):4. PMID: 22384486.
      Citations:    Fields:    Translation:Humans
    244. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondrial importance in Alzheimer's, Huntington's and Parkinson's diseases. Adv Exp Med Biol. 2012; 724:205-21. PMID: 22411245.
      Citations: 29     Fields:    Translation:HumansCells
    245. Perry G. Editorial: a new era for medicinal chemistry. Mini Rev Med Chem. 2012 Jan; 12(1):1. PMID: 22360667.
      Citations:    Fields:    
    246. Calder?n-Garcidue?as L, Kavanaugh M, Block M, D'Angiulli A, Delgado-Ch?vez R, Torres-Jard?n R, Gonz?lez-Maciel A, Reynoso-Robles R, Osnaya N, Villarreal-Calderon R, Guo R, Hua Z, Zhu H, Perry G, Diaz P. Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults. J Alzheimers Dis. 2012; 28(1):93-107. PMID: 21955814.
      Citations: 108     Fields:    Translation:HumansCellsPHPublic Health
    247. Perry GH, Melsted P, Marioni JC, Wang Y, Bainer R, Pickrell JK, Michelini K, Zehr S, Yoder AD, Stephens M, Pritchard JK, Gilad Y. Comparative RNA sequencing reveals substantial genetic variation in endangered primates. Genome Res. 2012 Apr; 22(4):602-10. PMID: 22207615.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    248. Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G, Zhu X. Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. J Neurochem. 2012 Feb; 120(3):419-29. PMID: 22077634.
      Citations: 205     Fields:    Translation:HumansCells
    249. Perry GH, Reeves D, Melsted P, Ratan A, Miller W, Michelini K, Louis EE, Pritchard JK, Mason CE, Gilad Y. A genome sequence resource for the aye-aye (Daubentonia madagascariensis), a nocturnal lemur from Madagascar. Genome Biol Evol. 2012; 4(2):126-35. PMID: 22155688.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    250. Colom LV, Castaneda MT, Hernandez S, Perry G, Jaime S, Touhami A. Intrahippocampal amyloid-? (1-40) injections injure medial septal neurons in rats. Curr Alzheimer Res. 2011 Dec; 8(8):832-40. PMID: 22044024.
      Citations: 12     Fields:    Translation:Animals
    251. Wise-Scira O, Xu L, Kitahara T, Perry G, Coskuner O. Amyloid-? peptide structure in aqueous solution varies with fragment size. J Chem Phys. 2011 Nov 28; 135(20):205101. PMID: 22128957.
      Citations: 21     Fields:    Translation:HumansCells
    252. Kudo W, Lee HP, Zou WQ, Wang X, Perry G, Zhu X, Smith MA, Petersen RB, Lee HG. Cellular prion protein is essential for oligomeric amyloid-?-induced neuronal cell death. Hum Mol Genet. 2012 Mar 01; 21(5):1138-44. PMID: 22100763.
      Citations: 66     Fields:    Translation:AnimalsCells
    253. Zhu X, Castellani RJ, Moreira PI, Aliev G, Shenk JC, Siedlak SL, Harris PLR, Fujioka H, Sayre LM, Szweda PA, Szweda LI, Smith MA, Perry G. Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover. Free Radic Biol Med. 2012 Feb 01; 52(3):699-704. PMID: 22137893.
      Citations: 18     Fields:    Translation:HumansCells
    254. Ziats NP, Petersen RB, Lee HG, Castellani RJ, Perry G, Zhu X. Mark A. Smith, 1965-2010: consummate student of pathogenesis. Int J Clin Exp Pathol. 2011; 4(7):731-2. PMID: 22076176.
      Citations:    Fields:    Translation:HumansAnimals
    255. Castellani RJ, Gupta Y, Sheng B, Siedlak SL, Harris PL, Coller JM, Perry G, Lee HG, Tabaton M, Smith MA, Wang X, Zhu X. A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules. Lab Invest. 2011 Dec; 91(12):1777-86. PMID: 21968813.
      Citations: 19     Fields:    Translation:HumansCells
    256. Castellani RJ, Petersen RB, Lee HG, Zhu X, Perry G. Mark A. Smith: the scientist, the man. Int J Exp Pathol. 2011 Oct; 92(5):297-8. PMID: 21917030.
      Citations:    Fields:    
    257. Bonda DJ, Castellani RJ, Zhu X, Nunomura A, Lee HG, Perry G, Smith MA. A novel perspective on tau in Alzheimer's disease. Curr Alzheimer Res. 2011 Sep; 8(6):639-42. PMID: 21605042.
      Citations: 14     Fields:    Translation:HumansCells
    258. Liu Q, Xie F, Alvarado-Diaz A, Smith MA, Moreira PI, Zhu X, Perry G. Neurofilamentopathy in neurodegenerative diseases. Open Neurol J. 2011; 5:58-62. PMID: 21915226.
      Citations:    
    259. Stone JG, Siedlak SL, Tabaton M, Hirano A, Castellani RJ, Santocanale C, Perry G, Smith MA, Zhu X, Lee HG. The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies. J Neuropathol Exp Neurol. 2011 Jul; 70(7):578-87. PMID: 21666500.
      Citations: 13     Fields:    Translation:HumansCells
    260. Wang X, Su B, Liu W, He X, Gao Y, Castellani RJ, Perry G, Smith MA, Zhu X. DLP1-dependent mitochondrial fragmentation mediates 1-methyl-4-phenylpyridinium toxicity in neurons: implications for Parkinson's disease. Aging Cell. 2011 Oct; 10(5):807-23. PMID: 21615675.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    261. Valdez CM, Phelix CF, Smith MA, Perry G, Santamaria F. Modeling cholesterol metabolism by gene expression profiling in the hippocampus. Mol Biosyst. 2011 Jun; 7(6):1891-901. PMID: 21451815.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    262. Bonda DJ, Lee HG, Blair JA, Zhu X, Perry G, Smith MA. Role of metal dyshomeostasis in Alzheimer's disease. Metallomics. 2011 Mar; 3(3):267-70. PMID: 21298161.
      Citations: 72     Fields:    Translation:HumansAnimals
    263. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease? Ageing Res Rev. 2011 Apr; 10(2):264-73. PMID: 21262392.
      Citations: 87     Fields:    Translation:AnimalsCells
    264. Britton GB, Smith MA, Perry G, Sambamurti K, Jagannatha Rao KS. Drug discovery for neurodegenerative diseases: challenges and novel biochemical targets dedicated to the memory of Mark A. Smith for his inspiring contribution to Alzheimer's disease. J Alzheimers Dis. 2011; 24 Suppl 2:1-2. PMID: 21525570.
      Citations: 1     Fields:    Translation:Humans
    265. Stone JG, Casadesus G, Gustaw-Rothenberg K, Siedlak SL, Wang X, Zhu X, Perry G, Castellani RJ, Smith MA. Frontiers in Alzheimer's disease therapeutics. Ther Adv Chronic Dis. 2011 Jan 01; 2(1):9-23. PMID: 21743833.
      Citations:    
    266. Bonda DJ, Smith MA, Perry G, Lee HG, Wang X, Zhu X. The mitochondrial dynamics of Alzheimer's disease and Parkinson's disease offer important opportunities for therapeutic intervention. Curr Pharm Des. 2011; 17(31):3374-80. PMID: 21902671.
      Citations: 17     Fields:    Translation:HumansCells
    267. Ashford JW, Salehi A, Furst A, Bayley P, Frisoni GB, Jack CR, Sabri O, Adamson MM, Coburn KL, Olichney J, Schuff N, Spielman D, Edland SD, Black S, Rosen A, Kennedy D, Weiner M, Perry G. Imaging the Alzheimer brain. J Alzheimers Dis. 2011; 26 Suppl 3:1-27. PMID: 21971448.
      Citations: 11     Fields:    Translation:Humans
    268. Correia SC, Cardoso S, Santos RX, Carvalho C, Santos MS, Perry G, Smith MA, Moreira PI. New insights into the mechanisms of mitochondrial preconditioning-triggered neuroprotection. Curr Pharm Des. 2011; 17(31):3381-9. PMID: 21902670.
      Citations: 14     Fields:    Translation:HumansCells
    269. Perry G, Zhu X. Mark Anthony Smith (1965-2010): Visionary, Alzheimer researcher, and editor-in-chief of the Journal of Alzheimer's Disease. J Alzheimers Dis. 2011; 24(1):1-2. PMID: 21383496.
      Citations:    Fields:    Translation:Humans
    270. Heath JE, Siedlak SL, Zhu X, Lee HG, Thakur A, Yan R, Perry G, Smith MA, Castellani RJ. Widespread distribution of reticulon-3 in various neurodegenerative diseases. Neuropathology. 2010 Dec; 30(6):574-9. PMID: 20374499.
      Citations: 12     Fields:    Translation:HumansCells
    271. Perry GH, Marioni JC, Melsted P, Gilad Y. Genomic-scale capture and sequencing of endogenous DNA from feces. Mol Ecol. 2010 Dec; 19(24):5332-44. PMID: 21054605.
      Citations: 41     Fields:    Translation:Animals
    272. Stone AC, Battistuzzi FU, Kubatko LS, Perry GH, Trudeau E, Lin H, Kumar S. More reliable estimates of divergence times in Pan using complete mtDNA sequences and accounting for population structure. Philos Trans R Soc Lond B Biol Sci. 2010 Oct 27; 365(1556):3277-88. PMID: 20855302.
      Citations: 28     Fields:    Translation:AnimalsCells
    273. Castellani RJ, Nugent SL, Morrison AL, Zhu X, Lee HG, Harris PL, Bajic V, Sharma HS, Chen SG, Oettgen P, Perry G, Smith MA. CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson's disease. J Neural Transm (Vienna). 2011 Jan; 118(1):23-6. PMID: 20972807.
      Citations: 7     Fields:    Translation:HumansCells
    274. Dwyer BE, Zacharski LR, Balestra DJ, Lerner AJ, Perry G, Zhu X, Smith MA. Potential role of iron in a Mediterranean-style diet. Arch Neurol. 2010 Oct; 67(10):1286-7; author reply 1287-8. PMID: 20937965.
      Citations: 2     Fields:    Translation:Humans
    275. Clark TA, Lee HP, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Casadesus G, Smith MA, Lee HG, Perry G. Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease. Int J Biomed Sci. 2010 Sep; 6(3):225-227. PMID: 21765811.
      Citations:    
    276. Correia SC, Carvalho C, Cardoso S, Santos RX, Santos MS, Oliveira CR, Perry G, Zhu X, Smith MA, Moreira PI. Mitochondrial preconditioning: a potential neuroprotective strategy. Front Aging Neurosci. 2010; 2. PMID: 20838473.
      Citations:    
    277. Buxton GA, Siedlak SL, Perry G, Smith MA. Mathematical modeling of microtubule dynamics: insights into physiology and disease. Prog Neurobiol. 2010 Dec; 92(4):478-83. PMID: 20713128.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    278. Valdez CM, Smith MA, Perry G, Phelix CF, Santamaria F. Cholesterol homeostasis markers are localized to mouse hippocampal pyramidal and granule layers. Hippocampus. 2010 Aug; 20(8):902-5. PMID: 20054815.
      Citations: 17     Fields:    Translation:AnimalsCells
    279. Zou WQ, Puoti G, Xiao X, Yuan J, Qing L, Cali I, Shimoji M, Langeveld JP, Castellani R, Notari S, Crain B, Schmidt RE, Geschwind M, Dearmond SJ, Cairns NJ, Dickson D, Honig L, Torres JM, Mastrianni J, Capellari S, Giaccone G, Belay ED, Schonberger LB, Cohen M, Perry G, Kong Q, Parchi P, Tagliavini F, Gambetti P. Variably protease-sensitive prionopathy: a new sporadic disease of the prion protein. Ann Neurol. 2010 Aug; 68(2):162-72. PMID: 20695009.
      Citations: 94     Fields:    Translation:Humans
    280. Guglielmotto M, Aragno M, Tamagno E, Vercellinatto I, Visentin S, Medana C, Catalano MG, Smith MA, Perry G, Danni O, Boccuzzi G, Tabaton M. AGEs/RAGE complex upregulates BACE1 via NF-?B pathway activation. Neurobiol Aging. 2012 Jan; 33(1):196.e13-27. PMID: 20638753.
      Citations: 63     Fields:    Translation:AnimalsCells
    281. Moreira PI, Santos RX, Zhu X, Lee HG, Smith MA, Casadesus G, Perry G. Autophagy in Alzheimer's disease. Expert Rev Neurother. 2010 Jul; 10(7):1209-18. PMID: 20586699.
      Citations: 20     Fields:    Translation:HumansCells
    282. Storace D, Cammarata S, Borghi R, Sanguineti R, Giliberto L, Piccini A, Pollero V, Novello C, Caltagirone C, Smith MA, Boss? P, Perry G, Odetti P, Tabaton M. Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment. Arch Neurol. 2010 Jul; 67(7):867-72. PMID: 20625095.
      Citations: 15     Fields:    Translation:Humans
    283. Nakamura M, Shishido N, Nunomura A, Smith MA, Perry G, Akutsu H, Hayashi T. Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid. Free Radic Res. 2010 Jul; 44(7):734-41. PMID: 20370566.
      Citations:    Fields:    Translation:HumansCells
    284. Lee HP, Zhu X, Casadesus G, Castellani RJ, Nunomura A, Smith MA, Lee HG, Perry G. Antioxidant approaches for the treatment of Alzheimer's disease. Expert Rev Neurother. 2010 Jul; 10(7):1201-8. PMID: 20586698.
      Citations: 39     Fields:    Translation:HumansAnimals
    285. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. Alzheimer's disease: diverse aspects of mitochondrial malfunctioning. Int J Clin Exp Pathol. 2010 Jun 25; 3(6):570-81. PMID: 20661404.
      Citations: 52     Fields:    Translation:HumansCells
    286. Moh CF, Siedlak SL, Tabaton M, Perry G, Castellani RJ, Smith MA. Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease. J Neurosci Methods. 2010 Jul 15; 190(2):244-7. PMID: 20580647.
      Citations: 3     Fields:    Translation:Humans
    287. Mondrag?n-Rodr?guez S, Basurto-Islas G, Lee HG, Perry G, Zhu X, Castellani RJ, Smith MA. Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis. Expert Rev Neurother. 2010 May; 10(5):683-91. PMID: 20420489.
      Citations: 22     Fields:    Translation:HumansCells
    288. Poeggeler B, Sambamurti K, Siedlak SL, Perry G, Smith MA, Pappolla MA. A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. PLoS One. 2010 Apr 21; 5(4):e10206. PMID: 20421998.
      Citations: 17     Fields:    Translation:AnimalsCells
    289. Bonda DJ, Wang X, Perry G, Nunomura A, Tabaton M, Zhu X, Smith MA. Oxidative stress in Alzheimer disease: a possibility for prevention. Neuropharmacology. 2010 Sep-Oct; 59(4-5):290-4. PMID: 20394761.
      Citations: 167     Fields:    Translation:HumansAnimalsCells
    290. Lee HP, Zhu X, Liu G, Chen SG, Perry G, Smith MA, Lee HG. Divalent metal transporter, iron, and Parkinson's disease: a pathological relationship. Cell Res. 2010 Apr; 20(4):397-9. PMID: 20357807.
      Citations: 8     Fields:    Translation:Humans
    291. Bonda DJ, Lee HP, Lee HG, Friedlich AL, Perry G, Zhu X, Smith MA. Novel therapeutics for Alzheimer's disease: an update. Curr Opin Drug Discov Devel. 2010 Mar; 13(2):235-46. PMID: 20205057.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    292. Bonda DJ, Wang X, Perry G, Smith MA, Zhu X. Mitochondrial dynamics in Alzheimer's disease: opportunities for future treatment strategies. Drugs Aging. 2010 Mar 01; 27(3):181-92. PMID: 20210366.
      Citations: 33     Fields:    Translation:HumansCells
    293. Wang X, Perry G, Smith MA, Zhu X. Amyloid-beta-derived diffusible ligands cause impaired axonal transport of mitochondria in neurons. Neurodegener Dis. 2010; 7(1-3):56-9. PMID: 20160460.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    294. Gustaw-Rothenberg K, Lerner A, Bonda DJ, Lee HG, Zhu X, Perry G, Smith MA. Biomarkers in Alzheimer's disease: past, present and future. Biomark Med. 2010 Feb; 4(1):15-26. PMID: 20387301.
      Citations: 28     Fields:    Translation:HumansCells
    295. Su B, Wang X, Bonda D, Perry G, Smith M, Zhu X. Abnormal mitochondrial dynamics--a novel therapeutic target for Alzheimer's disease? Mol Neurobiol. 2010 Jun; 41(2-3):87-96. PMID: 20101529.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    296. Avila J, Perry G, Mart?nez-Mart?n P. Prospects on the origin of Alzheimer's disease. J Alzheimers Dis. 2010; 20(2):669-72. PMID: 20505238.
      Citations: 3     Fields:    Translation:Humans
    297. Santos RX, Correia SC, Wang X, Perry G, Smith MA, Moreira PI, Zhu X. A synergistic dysfunction of mitochondrial fission/fusion dynamics and mitophagy in Alzheimer's disease. J Alzheimers Dis. 2010; 20 Suppl 2:S401-12. PMID: 20463393.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    298. Nair NG, Perry G, Smith MA, Reddy VP. NMR studies of zinc, copper, and iron binding to histidine, the principal metal ion complexing site of amyloid-beta peptide. J Alzheimers Dis. 2010; 20(1):57-66. PMID: 20164601.
      Citations: 37     Fields:    Translation:HumansCells
    299. Borghi R, Piccini A, Barini E, Cirmena G, Guglielmotto M, Tamagno E, Fornaro M, Perry G, Smith MA, Garuti A, Tabaton M. Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease. J Alzheimers Dis. 2010; 22(3):771-5. PMID: 20847436.
      Citations: 9     Fields:    Translation:HumansCells
    300. Correia SC, Santos RX, Perry G, Zhu X, Moreira PI, Smith MA. Mitochondria: the missing link between preconditioning and neuroprotection. J Alzheimers Dis. 2010; 20 Suppl 2:S475-85. PMID: 20463394.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    301. Smith MA, Zhu X, Tabaton M, Liu G, McKeel DW, Cohen ML, Wang X, Siedlak SL, Dwyer BE, Hayashi T, Nakamura M, Nunomura A, Perry G. Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment. J Alzheimers Dis. 2010; 19(1):363-72. PMID: 20061651.
      Citations: 150     Fields:    Translation:HumansAnimalsCells
    302. Liu G, Men P, Perry G, Smith MA. Nanoparticle and iron chelators as a potential novel Alzheimer therapy. Methods Mol Biol. 2010; 610:123-44. PMID: 20013176.
      Citations: 38     Fields:    Translation:HumansCells
    303. Moreira PI, Sayre LM, Zhu X, Nunomura A, Smith MA, Perry G. Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease. Methods Mol Biol. 2010; 610:419-34. PMID: 20013193.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    304. Bonda DJ, Mailankot M, Stone JG, Garrett MR, Staniszewska M, Castellani RJ, Siedlak SL, Zhu X, Lee HG, Perry G, Nagaraj RH, Smith MA. Indoleamine 2,3-dioxygenase and 3-hydroxykynurenine modifications are found in the neuropathology of Alzheimer's disease. Redox Rep. 2010; 15(4):161-8. PMID: 20663292.
      Citations: 48     Fields:    Translation:HumansCells
    305. Bonda DJ, Wang X, Gustaw-Rothenberg KA, Perry G, Smith MA, Zhu X. Mitochondrial Drugs for Alzheimer Disease. Pharmaceuticals (Basel). 2009 Dec 23; 2(3):287-298. PMID: 20657666.
      Citations:    
    306. Cardoso S, Santos R, Correia S, Carvalho C, Zhu X, Lee HG, Casadesus G, Smith MA, Perry G, Moreira PI. Insulin and Insulin-Sensitizing Drugs in Neurodegeneration: Mitochondria as Therapeutic Targets. Pharmaceuticals (Basel). 2009 Dec 23; 2(3):250-286. PMID: 27713238.
      Citations:    
    307. Nunomura A, Tamaoki T, Tanaka K, Motohashi N, Nakamura M, Hayashi T, Yamaguchi H, Shimohama S, Lee HG, Zhu X, Smith MA, Perry G. Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease. Neurobiol Dis. 2010 Mar; 37(3):731-7. PMID: 20034567.
      Citations: 38     Fields:    Translation:HumansCells
    308. Tabaton M, Perry G, Zhu X, Lee HG, Casadesus G, Smith MA. Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease. Am J Pathol. 2010 Feb; 176(2):540-1. PMID: 20019185.
      Citations: 1     Fields:    Translation:HumansAnimals
    309. Liu G, Men P, Perry G, Smith MA. Chapter 5 - Development of iron chelator-nanoparticle conjugates as potential therapeutic agents for Alzheimer disease. Prog Brain Res. 2009; 180:97-108. PMID: 20302830.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    310. Perry G, Moreira PI, Siedlak SL, Nunomura A, Zhu X, Smith MA. Natural oxidant balance in Parkinson disease. Arch Neurol. 2009 Dec; 66(12):1445. PMID: 20008647.
      Citations: 2     Fields:    Translation:Humans
    311. Su B, Wang X, Lee HG, Tabaton M, Perry G, Smith MA, Zhu X. Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells. Neurosci Lett. 2010 Jan 14; 468(3):267-71. PMID: 19914335.
      Citations: 68     Fields:    Translation:HumansCells
    312. Lee HP, Casadesus G, Zhu X, Lee HG, Perry G, Smith MA, Gustaw-Rothenberg K, Lerner A. All-trans retinoic acid as a novel therapeutic strategy for Alzheimer's disease. Expert Rev Neurother. 2009 Nov; 9(11):1615-21. PMID: 19903021.
      Citations: 36     Fields:    Translation:HumansAnimals
    313. Crain BJ, Terry RD, Perry G. 2009 award recipients--Peter C. Burger, MD, Pierluigi Gambetti, MD, and Nicholas K. Gonatas, MD. J Neuropathol Exp Neurol. 2009 Nov; 68(11):1244-6. PMID: 19901633.
      Citations:    Fields:    Translation:Humans
    314. Moreira PI, Carvalho C, Zhu X, Smith MA, Perry G. Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology. Biochim Biophys Acta. 2010 Jan; 1802(1):2-10. PMID: 19853658.
      Citations: 287     Fields:    Translation:HumansAnimalsCells
    315. Moreira PI, Zhu X, Wang X, Lee HG, Nunomura A, Petersen RB, Perry G, Smith MA. Mitochondria: a therapeutic target in neurodegeneration. Biochim Biophys Acta. 2010 Jan; 1802(1):212-20. PMID: 19853657.
      Citations: 108     Fields:    Translation:HumansAnimalsCells
    316. Gustaw-Rothenberg KA, Siedlak SL, Bonda DJ, Lerner A, Tabaton M, Perry G, Smith MA. Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study. Exp Gerontol. 2010 Jan; 45(1):47-52. PMID: 19819324.
      Citations: 16     Fields:    Translation:Humans
    317. Carvalho C, Correia SC, Santos RX, Cardoso S, Moreira PI, Clark TA, Zhu X, Smith MA, Perry G. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia. J Bioenerg Biomembr. 2009 Oct; 41(5):433-40. PMID: 19830532.
      Citations: 29     Fields:    Translation:HumansCells
    318. Su B, Wang X, Zheng L, Perry G, Smith MA, Zhu X. Abnormal mitochondrial dynamics and neurodegenerative diseases. Biochim Biophys Acta. 2010 Jan; 1802(1):135-42. PMID: 19799998.
      Citations: 121     Fields:    Translation:HumansAnimalsCells
    319. Tabaton M, Zhu X, Perry G, Smith MA, Giliberto L. Signaling effect of amyloid-beta(42) on the processing of AbetaPP. Exp Neurol. 2010 Jan; 221(1):18-25. PMID: 19747481.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    320. Su B, Liu H, Wang X, Chen SG, Siedlak SL, Kondo E, Choi R, Takeda A, Castellani RJ, Perry G, Smith MA, Zhu X, Lee HG. Ectopic localization of FOXO3a protein in Lewy bodies in Lewy body dementia and Parkinson's disease. Mol Neurodegener. 2009 Jul 23; 4:32. PMID: 19627592.
      Citations: 23     Fields:    
    321. Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci. 2009 Jul 15; 29(28):9090-103. PMID: 19605646.
      Citations: 588     Fields:    Translation:HumansAnimalsCells
    322. Friedlich AL, Rolston RK, Zhu X, Marlatt MW, Castellani RJ, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA. Treatment advances in Alzheimer's disease based on the oxidative stress model. F1000 Med Rep. 2009 Jul 08; 1. PMID: 20948726.
      Citations:    
    323. Dwyer BE, Stone ML, Gorman N, Sinclair PR, Perry G, Smith MA, Zhu X. Heme-a, the heme prosthetic group of cytochrome c oxidase, is increased in Alzheimer's disease. Neurosci Lett. 2009 Sep 25; 461(3):302-5. PMID: 19539709.
      Citations: 4     Fields:    Translation:HumansAnimals
    324. Liu G, Men P, Perry G, Smith MA. Metal chelators coupled with nanoparticles as potential therapeutic agents for Alzheimer's disease. J Nanoneurosci. 2009 Jun 01; 1(1):42-55. PMID: 19936278.
      Citations:    
    325. Dwyer BE, Smith MA, Richardson SL, Perry G, Zhu X. Down-regulation of aminolevulinate synthase, the rate-limiting enzyme for heme biosynthesis in Alzheimer's disease. Neurosci Lett. 2009 Aug 28; 460(2):180-4. PMID: 19477221.
      Citations: 12     Fields:    Translation:HumansCells
    326. Perez M, Santa-Maria I, Gomez de Barreda E, Zhu X, Cuadros R, Cabrero JR, Sanchez-Madrid F, Dawson HN, Vitek MP, Perry G, Smith MA, Avila J. Tau--an inhibitor of deacetylase HDAC6 function. J Neurochem. 2009 Jun; 109(6):1756-66. PMID: 19457097.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    327. Wang X, Su B, Zheng L, Perry G, Smith MA, Zhu X. The role of abnormal mitochondrial dynamics in the pathogenesis of Alzheimer's disease. J Neurochem. 2009 May; 109 Suppl 1:153-9. PMID: 19393022.
      Citations: 139     Fields:    Translation:HumansAnimalsCells
    328. Bonda DJ, Evans TA, Santocanale C, Llos? JC, Vi?a J, Bajic V, Castellani RJ, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence for the progression through S-phase in the ectopic cell cycle re-entry of neurons in Alzheimer disease. Aging (Albany NY). 2009 Apr; 1(4):382-8. PMID: 19946466.
      Citations: 47     Fields:    Translation:HumansCells
    329. Castellani RJ, Zhu X, Lee HG, Smith MA, Perry G. Molecular pathogenesis of Alzheimer's disease: reductionist versus expansionist approaches. Int J Mol Sci. 2009 Mar; 10(3):1386-1406. PMID: 19399255.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    330. Liu G, Men P, Kudo W, Perry G, Smith MA. Nanoparticle-chelator conjugates as inhibitors of amyloid-beta aggregation and neurotoxicity: a novel therapeutic approach for Alzheimer disease. Neurosci Lett. 2009 May 22; 455(3):187-90. PMID: 19429118.
      Citations: 35     Fields:    Translation:HumansCells
    331. Nunomura A, Hofer T, Moreira PI, Castellani RJ, Smith MA, Perry G. RNA oxidation in Alzheimer disease and related neurodegenerative disorders. Acta Neuropathol. 2009 Jul; 118(1):151-66. PMID: 19271225.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    332. Rajendran R, Minqin R, Ynsa MD, Casadesus G, Smith MA, Perry G, Halliwell B, Watt F. A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease. Biochem Biophys Res Commun. 2009 Apr 24; 382(1):91-5. PMID: 19258010.
      Citations: 33     Fields:    Translation:Animals
    333. Perry GH, Dominy NJ. Evolution of the human pygmy phenotype. Trends Ecol Evol. 2009 Apr; 24(4):218-25. PMID: 19246118.
      Citations: 52     Fields:    Translation:Humans
    334. Dwyer BE, Zacharski LR, Balestra DJ, Lerner AJ, Perry G, Zhu X, Smith MA. Getting the iron out: phlebotomy for Alzheimer's disease? Med Hypotheses. 2009 May; 72(5):504-9. PMID: 19195795.
      Citations: 11     Fields:    Translation:Humans
    335. Perry G, Zhu X, Moreira PI, Smith MA. Altered redox balance in disease: can we change the new equilibria? Ann Neurol. 2009 Feb; 65(2):121-3. PMID: 19259960.
      Citations: 2     Fields:    Translation:HumansCells
    336. Siedlak SL, Casadesus G, Webber KM, Pappolla MA, Atwood CS, Smith MA, Perry G. Chronic antioxidant therapy reduces oxidative stress in a mouse model of Alzheimer's disease. Free Radic Res. 2009 Feb; 43(2):156-64. PMID: 19160110.
      Citations: 34     Fields:    Translation:Animals
    337. Guglielmotto M, Aragno M, Autelli R, Giliberto L, Novo E, Colombatto S, Danni O, Parola M, Smith MA, Perry G, Tamagno E, Tabaton M. The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha. J Neurochem. 2009 Feb; 108(4):1045-56. PMID: 19196431.
      Citations: 109     Fields:    Translation:HumansAnimalsCells
    338. Rolston RK, Perry G, Zhu X, Castellani RJ, Dwyer BE, Lee HG, Petersen RB, Smith MA. Iron: A Pathological Mediator of Alzheimer Disease? Agro Food Ind Hi Tech. 2009 Jan 31; 19(6):33-36. PMID: 21544251.
      Citations:    
    339. Lee HG, Casadesus G, Nunomura A, Zhu X, Castellani RJ, Richardson SL, Perry G, Felsher DW, Petersen RB, Smith MA. The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse. Am J Pathol. 2009 Mar; 174(3):891-7. PMID: 19164506.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    340. Lee HP, Zhu X, Zhu X, Skidmore SC, Perry G, Sayre LM, Smith MA, Lee HG. The essential role of ERK in 4-oxo-2-nonenal-mediated cytotoxicity in SH-SY5Y human neuroblastoma cells. J Neurochem. 2009 Mar; 108(6):1434-41. PMID: 19183271.
      Citations: 6     Fields:    Translation:HumansCells
    341. Tezapsidis N, Johnston JM, Smith MA, Ashford JW, Casadesus G, Robakis NK, Wolozin B, Perry G, Zhu X, Greco SJ, Sarkar S. Leptin: a novel therapeutic strategy for Alzheimer's disease. J Alzheimers Dis. 2009; 16(4):731-40. PMID: 19387109.
      Citations: 50     Fields:    Translation:HumansAnimals
    342. Reddy VP, Zhu X, Perry G, Smith MA. Oxidative stress in diabetes and Alzheimer's disease. J Alzheimers Dis. 2009; 16(4):763-74. PMID: 19387111.
      Citations: 84     Fields:    Translation:HumansAnimals
    343. Cardoso S, Correia S, Santos RX, Carvalho C, Santos MS, Oliveira CR, Perry G, Smith MA, Zhu X, Moreira PI. Insulin is a two-edged knife on the brain. J Alzheimers Dis. 2009; 18(3):483-507. PMID: 19542630.
      Citations: 24     Fields:    Translation:Humans
    344. Castellani RJ, Lee HG, Siedlak SL, Nunomura A, Hayashi T, Nakamura M, Zhu X, Perry G, Smith MA. Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta. J Alzheimers Dis. 2009; 18(2):447-52. PMID: 19584435.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    345. Lee HG, Casadesus G, Zhu X, Castellani RJ, McShea A, Perry G, Petersen RB, Bajic V, Smith MA. Cell cycle re-entry mediated neurodegeneration and its treatment role in the pathogenesis of Alzheimer's disease. Neurochem Int. 2009 Feb; 54(2):84-8. PMID: 19114068.
      Citations: 68     Fields:    Translation:Humans
    346. Pallas M, Camins A, Smith MA, Perry G, Lee HG, Casadesus G. From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). J Alzheimers Dis. 2008 Dec; 15(4):615-24. PMID: 19096160.
      Citations: 81     Fields:    Translation:Animals
    347. Su B, Wang X, Nunomura A, Moreira PI, Lee HG, Perry G, Smith MA, Zhu X. Oxidative stress signaling in Alzheimer's disease. Curr Alzheimer Res. 2008 Dec; 5(6):525-32. PMID: 19075578.
      Citations: 108     Fields:    Translation:HumansAnimalsCells
    348. Ramiro-Puig E, Casades?s G, Lee HG, Zhu X, McShea A, Perry G, P?rez-Cano FJ, Smith MA, Castell M. Neuroprotective effect of cocoa flavonoids on in vitro oxidative stress. Eur J Nutr. 2009 Feb; 48(1):54-61. PMID: 19043659.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    349. Lee HG, Zhu X, Casadesus G, Pall?s M, Camins A, O'Neill MJ, Nakanishi S, Perry G, Smith MA. The effect of mGluR2 activation on signal transduction pathways and neuronal cell survival. Brain Res. 2009 Jan 16; 1249:244-50. PMID: 19026996.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    350. Aliev G, Obrenovich ME, Reddy VP, Shenk JC, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Antioxidant therapy in Alzheimer's disease: theory and practice. Mini Rev Med Chem. 2008 Nov; 8(13):1395-406. PMID: 18991755.
      Citations: 43     Fields:    Translation:HumansAnimals
    351. Stone JG, Rolston RK, Ueda M, Lee HG, Richardson SL, Castellani RJ, Perry G, Smith MA. Evidence for the novel expression of human kallikrein-related peptidase 3, prostate-specific antigen, in the brain. Int J Clin Exp Pathol. 2009; 2(3):267-74. PMID: 19079621.
      Citations: 2     Fields:    
    352. Obrenovich ME, Morales LA, Cobb CJ, Shenk JC, M?ndez GM, Fischbach K, Smith MA, Qasimov EK, Perry G, Aliev G. Insights into cerebrovascular complications and Alzheimer disease through the selective loss of GRK2 regulation. J Cell Mol Med. 2009 May; 13(5):853-65. PMID: 19292735.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    353. Marlatt MW, Lucassen PJ, Perry G, Smith MA, Zhu X. Alzheimer's disease: cerebrovascular dysfunction, oxidative stress, and advanced clinical therapies. J Alzheimers Dis. 2008 Oct; 15(2):199-210. PMID: 18953109.
      Citations: 30     Fields:    Translation:Humans
    354. Verrelli BC, Lewis CM, Stone AC, Perry GH. Different selective pressures shape the molecular evolution of color vision in chimpanzee and human populations. Mol Biol Evol. 2008 Dec; 25(12):2735-43. PMID: 18832077.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    355. Bryan KJ, Zhu X, Harris PL, Perry G, Castellani RJ, Smith MA, Casadesus G. Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease. Mol Neurodegener. 2008 Sep 11; 3:13. PMID: 18786268.
      Citations: 36     Fields:    
    356. Gelfand SL, Vento M, Sastre J, Lust WD, Smith MA, Perry G, Walsh M, Martin R. A new model of oxidative stress in rat pups. Neonatology. 2008; 94(4):293-9. PMID: 18784426.
      Citations: 4     Fields:    Translation:HumansAnimals
    357. Perry GH, Yang F, Marques-Bonet T, Murphy C, Fitzgerald T, Lee AS, Hyland C, Stone AC, Hurles ME, Tyler-Smith C, Eichler EE, Carter NP, Lee C, Redon R. Copy number variation and evolution in humans and chimpanzees. Genome Res. 2008 Nov; 18(11):1698-710. PMID: 18775914.
      Citations: 132     Fields:    Translation:HumansAnimalsCells
    358. Castellani RJ, Nunomura A, Lee HG, Perry G, Smith MA. Phosphorylated tau: toxic, protective, or none of the above. J Alzheimers Dis. 2008 Aug; 14(4):377-83. PMID: 18688087.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    359. Aliev G, Shenk JC, Fischbach K, Perry G. Stem cell niches as clinical targets: the future of anti-ischemic therapy? Nat Clin Pract Cardiovasc Med. 2008 Sep; 5(9):590-1. PMID: 18628773.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    360. Collingwood JF, Chong RK, Kasama T, Cervera-Gontard L, Dunin-Borkowski RE, Perry G, P?sfai M, Siedlak SL, Simpson ET, Smith MA, Dobson J. Three-dimensional tomographic imaging and characterization of iron compounds within Alzheimer's plaque core material. J Alzheimers Dis. 2008 Jun; 14(2):235-45. PMID: 18560134.
      Citations: 48     Fields:    Translation:Humans
    361. Castellani RJ, Lee HG, Zhu X, Perry G, Smith MA. Alzheimer disease pathology as a host response. J Neuropathol Exp Neurol. 2008 Jun; 67(6):523-31. PMID: 18520771.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    362. Su B, Wang X, Drew KL, Perry G, Smith MA, Zhu X. Physiological regulation of tau phosphorylation during hibernation. J Neurochem. 2008 Jun 01; 105(6):2098-108. PMID: 18284615.
      Citations: 39     Fields:    Translation:AnimalsCells
    363. Friedland RP, Tedesco JM, Wilson AC, Atwood CS, Smith MA, Perry G, Zagorski MG. Antibodies to potato virus Y bind the amyloid beta peptide: immunohistochemical and NMR studies. J Biol Chem. 2008 Aug 15; 283(33):22550-6. PMID: 18505725.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    364. Castellani RJ, Nunomura A, Rolston RK, Moreira PI, Takeda A, Perry G, Smith MA. Sublethal RNA oxidation as a mechanism for neurodegenerative disease. Int J Mol Sci. 2008 May; 9(5):789-806. PMID: 19325784.
      Citations: 20     Fields:    
    365. Gustaw KA, Garrett MR, Lee HG, Castellani RJ, Zagorski MG, Prakasam A, Siedlak SL, Zhu X, Perry G, Petersen RB, Friedland RP, Smith MA. Antigen-antibody dissociation in Alzheimer disease: a novel approach to diagnosis. J Neurochem. 2008 Aug; 106(3):1350-6. PMID: 18485104.
      Citations: 25     Fields:    Translation:HumansAnimals
    366. Myung NH, Zhu X, Kruman II, Castellani RJ, Petersen RB, Siedlak SL, Perry G, Smith MA, Lee HG. Evidence of DNA damage in Alzheimer disease: phosphorylation of histone H2AX in astrocytes. Age (Dordr). 2008 Dec; 30(4):209-15. PMID: 19424844.
      Citations: 56     Fields:    
    367. Ionita-Laza I, Perry GH, Raby BA, Klanderman B, Lee C, Laird NM, Weiss ST, Lange C. On the analysis of copy-number variations in genome-wide association studies: a translation of the family-based association test. Genet Epidemiol. 2008 Apr; 32(3):273-84. PMID: 18228561.
      Citations: 34     Fields:    Translation:Humans
    368. Mondrag?n-Rodr?guez S, Basurto-Islas G, Santa-Maria I, Mena R, Binder LI, Avila J, Smith MA, Perry G, Garc?a-Sierra F. Cleavage and conformational changes of tau protein follow phosphorylation during Alzheimer's disease. Int J Exp Pathol. 2008 Apr; 89(2):81-90. PMID: 18336525.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    369. Aliev G, Liu J, Shenk JC, Fischbach K, Pacheco GJ, Chen SG, Obrenovich ME, Ward WF, Richardson AG, Smith MA, Gasimov E, Perry G, Ames BN. Neuronal mitochondrial amelioration by feeding acetyl-L-carnitine and lipoic acid to aged rats. J Cell Mol Med. 2009 Feb; 13(2):320-33. PMID: 18373733.
      Citations: 38     Fields:    Translation:AnimalsCells
    370. Shah RS, Lee HG, Xiongwei Z, Perry G, Smith MA, Castellani RJ. Current approaches in the treatment of Alzheimer's disease. Biomed Pharmacother. 2008 Apr-May; 62(4):199-207. PMID: 18407457.
      Citations: 39     Fields:    Translation:HumansPHPublic Health
    371. Perry G, Zhu X, Babar AK, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Chen SG. Leucine-rich repeat kinase 2 colocalizes with alpha-synuclein in Parkinson's disease, but not tau-containing deposits in tauopathies. Neurodegener Dis. 2008; 5(3-4):222-4. PMID: 18322396.
      Citations: 18     Fields:    Translation:Humans
    372. Gonzalez-Cuyar LF, Perry G, Miyajima H, Atwood CS, Riveros-Angel M, Lyons PF, Siedlak SL, Smith MA, Castellani RJ. Redox active iron accumulation in aceruloplasminemia. Neuropathology. 2008 Oct; 28(5):466-71. PMID: 18282164.
      Citations: 18     Fields:    Translation:HumansCells
    373. Moreira PI, Santos MS, Oliveira CR, Shenk JC, Nunomura A, Smith MA, Zhu X, Perry G. Alzheimer disease and the role of free radicals in the pathogenesis of the disease. CNS Neurol Disord Drug Targets. 2008 Feb; 7(1):3-10. PMID: 18289026.
      Citations: 57     Fields:    Translation:HumansAnimals
    374. Perry GH, Ben-Dor A, Tsalenko A, Sampas N, Rodriguez-Revenga L, Tran CW, Scheffer A, Steinfeld I, Tsang P, Yamada NA, Park HS, Kim JI, Seo JS, Yakhini Z, Laderman S, Bruhn L, Lee C. The fine-scale and complex architecture of human copy-number variation. Am J Hum Genet. 2008 Mar; 82(3):685-95. PMID: 18304495.
      Citations: 171     Fields:    Translation:HumansCells
    375. Chan HW, Liu T, Verdile G, Bishop G, Haasl RJ, Smith MA, Perry G, Martins RN, Atwood CS. Copper Induces Apoptosis of Neuroblastoma Cells Via Post-translational Regulation of the Expression of Bcl-2-family Proteins and the tx Mouse is a Better Model of Hepatic than Brain Cu Toxicity. Int J Clin Exp Med. 2008; 1(1):76-88. PMID: 19079689.
      Citations:    
    376. Moreira PI, Nunomura A, Nakamura M, Takeda A, Shenk JC, Aliev G, Smith MA, Perry G. Nucleic acid oxidation in Alzheimer disease. Free Radic Biol Med. 2008 Apr 15; 44(8):1493-505. PMID: 18258207.
      Citations: 88     Fields:    Translation:HumansAnimalsCells
    377. Lee AS, Guti?rrez-Arcelus M, Perry GH, Vallender EJ, Johnson WE, Miller GM, Korbel JO, Lee C. Analysis of copy number variation in the rhesus macaque genome identifies candidate loci for evolutionary and human disease studies. Hum Mol Genet. 2008 Apr 15; 17(8):1127-36. PMID: 18180252.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    378. Casadesus G, Rolston RK, Webber KM, Atwood CS, Bowen RL, Perry G, Smith MA. Menopause, estrogen, and gonadotropins in Alzheimer's disease. Adv Clin Chem. 2008; 45:139-53. PMID: 18429496.
      Citations: 3     Fields:    Translation:Humans
    379. Thakur A, Siedlak SL, James SL, Bonda DJ, Rao A, Webber KM, Camins A, Pall?s M, Casadesus G, Lee HG, Bowser R, Raina AK, Perry G, Smith MA, Zhu X. Retinoblastoma protein phosphorylation at multiple sites is associated with neurofibrillary pathology in Alzheimer disease. Int J Clin Exp Pathol. 2008 Jan 01; 1(2):134-46. PMID: 18784806.
      Citations: 22     Fields:    
    380. Aliev G, Gasimov E, Obrenovich ME, Fischbach K, Shenk JC, Smith MA, Perry G. Atherosclerotic lesions and mitochondria DNA deletions in brain microvessels: implication in the pathogenesis of Alzheimer's disease. Vasc Health Risk Manag. 2008; 4(3):721-30. PMID: 18827923.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    381. Perry G, Castellani RJ, Moreira PI, Lee HG, Zhu X, Smith MA. Pathology's new role: defining disease process and protective responses. Int J Clin Exp Pathol. 2008 Jan 01; 1(1):1-4. PMID: 18784818.
      Citations: 1     Fields:    
    382. Sayre LM, Perry G, Smith MA. Oxidative stress and neurotoxicity. Chem Res Toxicol. 2008 Jan; 21(1):172-88. PMID: 18052107.
      Citations: 225     Fields:    Translation:HumansAnimalsCells
    383. Webber KM, Casadesus G, Bowen RL, Perry G, Smith MA. Evidence for the role of luteinizing hormone in Alzheimer disease. Endocr Metab Immune Disord Drug Targets. 2007 Dec; 7(4):300-3. PMID: 18220951.
      Citations: 7     Fields:    Translation:HumansAnimals
    384. Castellani RJ, Perry G, Smith MA. The role of novel chitin-like polysaccharides in Alzheimer disease. Neurotox Res. 2007 Dec; 12(4):269-74. PMID: 18201954.
      Citations: 14     Fields:    Translation:HumansAnimals
    385. Nunomura A, Moreira PI, Lee HG, Zhu X, Castellani RJ, Smith MA, Perry G. Neuronal death and survival under oxidative stress in Alzheimer and Parkinson diseases. CNS Neurol Disord Drug Targets. 2007 Dec; 6(6):411-23. PMID: 18220780.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    386. Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PG, Clark RS, Clarke SG, Clav? C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Dr?ge W, Dron M, Dunn WA, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, F?s?s L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, Gonz?lez-Est?vez C, Gorski S, Gottlieb RA, H?ussinger D, He YW, Heidenreich K, Hill JA, H?yer-Hansen M, Hu X, Huang WP, Iwasaki A, J??ttel? M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JA, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kov?cs AL, Kroemer G, Kuan CY, Kumar R, Kundu M, Landry J, Laporte M, Le W, Lei HY, Lenardo MJ, Levine B, Lieberman A, Lim KL, Lin FC, Liou W, Liu LF, Lopez-Berestein G, L?pez-Ot?n C, Lu B, Macleod KF, Malorni W, Martinet W, Matsuoka K, Mautner J, Meijer AJ, Mel?ndez A, Michels P, Miotto G, Mistiaen WP, Mizushima N, Mograbi B, Monastyrska I, Moore MN, Moreira PI, Moriyasu Y, Motyl T, M?nz C, Murphy LO, Naqvi NI, Neufeld TP, Nishino I, Nixon RA, Noda T, N?rnberg B, Ogawa M, Oleinick NL, Olsen LJ, Ozpolat B, Paglin S, Palmer GE, Papassideri I, Parkes M, Perlmutter DH, Perry G, Piacentini M, Pinkas-Kramarski R, Prescott M, Proikas-Cezanne T, Raben N, Rami A, Reggiori F, Rohrer B, Rubinsztein DC, Ryan KM, Sadoshima J, Sakagami H, Sakai Y, Sandri M, Sasakawa C, Sass M, Schneider C, Seglen PO, Seleverstov O, Settleman J, Shacka JJ, Shapiro IM, Sibirny A, Silva-Zacarin EC, Simon HU, Simone C, Simonsen A, Smith MA, Spanel-Borowski K, Srinivas V, Steeves M, Stenmark H, Stromhaug PE, Subauste CS, Sugimoto S, Sulzer D, Suzuki T, Swanson MS, Tabas I, Takeshita F, Talbot NJ, Tall?czy Z, Tanaka K, Tanaka K, Tanida I, Taylor GS, Taylor JP, Terman A, Tettamanti G, Thompson CB, Thumm M, Tolkovsky AM, Tooze SA, Truant R, Tumanovska LV, Uchiyama Y, Ueno T, Uzc?tegui NL, van der Klei I, Vaquero EC, Vellai T, Vogel MW, Wang HG, Webster P, Wiley JW, Xi Z, Xiao G, Yahalom J, Yang JM, Yap G, Yin XM, Yoshimori T, Yu L, Yue Z, Yuzaki M, Zabirnyk O, Zheng X, Zhu X, Deter RL. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy. 2008 Feb; 4(2):151-75. PMID: 18188003.
      Citations: 1199     Fields:    Translation:HumansAnimalsCells
    387. Tamagno E, Guglielmotto M, Aragno M, Borghi R, Autelli R, Giliberto L, Muraca G, Danni O, Zhu X, Smith MA, Perry G, Jo DG, Mattson MP, Tabaton M. Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein. J Neurochem. 2008 Feb; 104(3):683-95. PMID: 18005001.
      Citations: 131     Fields:    Translation:AnimalsCells
    388. Zhu X, Siedlak SL, Wang Y, Perry G, Castellani RJ, Cohen ML, Smith MA. Neuronal binucleation in Alzheimer disease hippocampus. Neuropathol Appl Neurobiol. 2008 Aug; 34(4):457-65. PMID: 17995921.
      Citations: 35     Fields:    Translation:HumansCells
    389. Mondrag?n-Rodr?guez S, Mena R, Binder LI, Smith MA, Perry G, Garc?a-Sierra F. Conformational changes and cleavage of tau in Pick bodies parallel the early processing of tau found in Alzheimer pathology. Neuropathol Appl Neurobiol. 2008 Feb; 34(1):62-75. PMID: 17971079.
      Citations: 22     Fields:    Translation:HumansCells
    390. Nakamura M, Shishido N, Nunomura A, Smith MA, Perry G, Hayashi Y, Nakayama K, Hayashi T. Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron. Biochemistry. 2007 Nov 06; 46(44):12737-43. PMID: 17929832.
      Citations: 65     Fields:    Translation:HumansCells
    391. Webber KM, Perry G, Smith MA, Casadesus G. The contribution of luteinizing hormone to Alzheimer disease pathogenesis. Clin Med Res. 2007 Oct; 5(3):177-83. PMID: 18056027.
      Citations: 12     Fields:    Translation:HumansAnimals
    392. Liu Q, Ju WK, Crowston JG, Xie F, Perry G, Smith MA, Lindsey JD, Weinreb RN. Oxidative stress is an early event in hydrostatic pressure induced retinal ganglion cell damage. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4580-9. PMID: 17898281.
      Citations: 65     Fields:    Translation:AnimalsCells
    393. Wang X, Su B, Perry G, Smith MA, Zhu X. Insights into amyloid-beta-induced mitochondrial dysfunction in Alzheimer disease. Free Radic Biol Med. 2007 Dec 15; 43(12):1569-73. PMID: 18037122.
      Citations: 42     Fields:    Translation:HumansCells
    394. Perry GH, Dominy NJ, Claw KG, Lee AS, Fiegler H, Redon R, Werner J, Villanea FA, Mountain JL, Misra R, Carter NP, Lee C, Stone AC. Diet and the evolution of human amylase gene copy number variation. Nat Genet. 2007 Oct; 39(10):1256-60. PMID: 17828263.
      Citations: 511     Fields:    Translation:HumansAnimals
    395. Zhu X, Su B, Wang X, Smith MA, Perry G. Causes of oxidative stress in Alzheimer disease. Cell Mol Life Sci. 2007 Sep; 64(17):2202-10. PMID: 17605000.
      Citations: 111     Fields:    Translation:HumansCells
    396. Moreira PI, Harris PL, Zhu X, Santos MS, Oliveira CR, Smith MA, Perry G. Lipoic acid and N-acetyl cysteine decrease mitochondrial-related oxidative stress in Alzheimer disease patient fibroblasts. J Alzheimers Dis. 2007 Sep; 12(2):195-206. PMID: 17917164.
      Citations: 72     Fields:    Translation:HumansCells
    397. Hayashi T, Shishido N, Nakayama K, Nunomura A, Smith MA, Perry G, Nakamura M. Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide. Free Radic Biol Med. 2007 Dec 01; 43(11):1552-9. PMID: 17964426.
      Citations: 28     Fields:    Translation:HumansCells
    398. Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Increased autophagic degradation of mitochondria in Alzheimer disease. Autophagy. 2007 Nov-Dec; 3(6):614-5. PMID: 17786024.
      Citations: 72     Fields:    Translation:HumansCells
    399. Perry GH, Martin RD, Verrelli BC. Signatures of functional constraint at aye-aye opsin genes: the potential of adaptive color vision in a nocturnal primate. Mol Biol Evol. 2007 Sep; 24(9):1963-70. PMID: 17575304.
      Citations: 16     Fields:    Translation:Animals
    400. Moreira PI, Siedlak SL, Wang X, Santos MS, Oliveira CR, Tabaton M, Nunomura A, Szweda LI, Aliev G, Smith MA, Zhu X, Perry G. Autophagocytosis of mitochondria is prominent in Alzheimer disease. J Neuropathol Exp Neurol. 2007 Jun; 66(6):525-32. PMID: 17549012.
      Citations: 66     Fields:    Translation:HumansCells
    401. Thakur A, Wang X, Siedlak SL, Perry G, Smith MA, Zhu X. c-Jun phosphorylation in Alzheimer disease. J Neurosci Res. 2007 Jun; 85(8):1668-73. PMID: 17455299.
      Citations: 33     Fields:    Translation:HumansCells
    402. Castellani RJ, Moreira PI, Liu G, Dobson J, Perry G, Smith MA, Zhu X. Iron: the Redox-active center of oxidative stress in Alzheimer disease. Neurochem Res. 2007 Oct; 32(10):1640-5. PMID: 17508283.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    403. Evans TA, Raina AK, Delacourte A, Aprelikova O, Lee HG, Zhu X, Perry G, Smith MA. BRCA1 may modulate neuronal cell cycle re-entry in Alzheimer disease. Int J Med Sci. 2007 May 12; 4(3):140-5. PMID: 17505559.
      Citations: 33     Fields:    Translation:HumansCells
    404. Castellani RJ, Zhu X, Lee HG, Moreira PI, Perry G, Smith MA. Neuropathology and treatment of Alzheimer disease: did we lose the forest for the trees? Expert Rev Neurother. 2007 May; 7(5):473-85. PMID: 17492899.
      Citations: 13     Fields:    Translation:HumansAnimals
    405. Petersen RB, Nunomura A, Lee HG, Casadesus G, Perry G, Smith MA, Zhu X. Signal transduction cascades associated with oxidative stress in Alzheimer's disease. J Alzheimers Dis. 2007 May; 11(2):143-52. PMID: 17522439.
      Citations: 37     Fields:    Translation:HumansCells
    406. Zhu X, Avila J, Perry G, Smith MA. Treating the lesions, not the disease. Am J Pathol. 2007 May; 170(5):1457-9. PMID: 17456753.
      Citations: 4     Fields:    Translation:HumansAnimals
    407. Parker-Katiraee L, Carson AR, Yamada T, Arnaud P, Feil R, Abu-Amero SN, Moore GE, Kaneda M, Perry GH, Stone AC, Lee C, Meguro-Horike M, Sasaki H, Kobayashi K, Nakabayashi K, Scherer SW. Identification of the imprinted KLF14 transcription factor undergoing human-specific accelerated evolution. PLoS Genet. 2007 May 04; 3(5):e65. PMID: 17480121.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    408. Casadesus G, Moreira PI, Nunomura A, Siedlak SL, Bligh-Glover W, Balraj E, Petot G, Smith MA, Perry G. Indices of metabolic dysfunction and oxidative stress. Neurochem Res. 2007 Apr-May; 32(4-5):717-22. PMID: 17342408.
      Citations: 9     Fields:    Translation:HumansCells
    409. Zhu X, Smith MA, Honda K, Aliev G, Moreira PI, Nunomura A, Casadesus G, Harris PL, Siedlak SL, Perry G. Vascular oxidative stress in Alzheimer disease. J Neurol Sci. 2007 Jun 15; 257(1-2):240-6. PMID: 17337008.
      Citations: 66     Fields:    Translation:HumansCells
    410. Casadesus G, Milliken EL, Webber KM, Bowen RL, Lei Z, Rao CV, Perry G, Keri RA, Smith MA. Increases in luteinizing hormone are associated with declines in cognitive performance. Mol Cell Endocrinol. 2007 Apr 15; 269(1-2):107-11. PMID: 17376589.
      Citations: 41     Fields:    Translation:Animals
    411. Wung JK, Perry G, Kowalski A, Harris PL, Bishop GM, Trivedi MA, Johnson SC, Smith MA, Denhardt DT, Atwood CS. Increased expression of the remodeling- and tumorigenic-associated factor osteopontin in pyramidal neurons of the Alzheimer's disease brain. Curr Alzheimer Res. 2007 Feb; 4(1):67-72. PMID: 17316167.
      Citations: 40     Fields:    Translation:HumansCells
    412. Liu Q, Xie F, Rolston R, Moreira PI, Nunomura A, Zhu X, Smith MA, Perry G. Prevention and treatment of Alzheimer disease and aging: antioxidants. Mini Rev Med Chem. 2007 Feb; 7(2):171-80. PMID: 17305591.
      Citations: 17     Fields:    Translation:HumansAnimals
    413. Casadesus G, Smith MA, Basu S, Hua J, Capobianco DE, Siedlak SL, Zhu X, Perry G. Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. Mol Neurodegener. 2007 Jan 22; 2:2. PMID: 17241462.
      Citations: 15     Fields:    
    414. Lee HG, Zhu X, Castellani RJ, Nunomura A, Perry G, Smith MA. Amyloid-beta in Alzheimer disease: the null versus the alternate hypotheses. J Pharmacol Exp Ther. 2007 Jun; 321(3):823-9. PMID: 17229880.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    415. Perry GH, Tito RY, Verrelli BC. The evolutionary history of human and chimpanzee Y-chromosome gene loss. Mol Biol Evol. 2007 Mar; 24(3):853-9. PMID: 17218643.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    416. Gonzalez-Cuyar LF, Hunter B, Harris PL, Perry G, Smith MA, Castellani RJ. Cerebrotendinous xanthomatosis: case report with evidence of oxidative stress. Redox Rep. 2007; 12(3):119-24. PMID: 17623518.
      Citations: 7     Fields:    Translation:Humans
    417. Bishop GM, Smith MA, LaManna JC, Wilson AC, Perry G, Atwood CS. Iron homeostasis is maintained in the brain, but not the liver, following mild hypoxia. Redox Rep. 2007; 12(6):257-66. PMID: 17961297.
      Citations: 5     Fields:    Translation:AnimalsCells
    418. Nunomura A, Moreira PI, Takeda A, Smith MA, Perry G. Oxidative RNA damage and neurodegeneration. Curr Med Chem. 2007; 14(28):2968-75. PMID: 18220733.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    419. Lee HG, Ueda M, Zhu X, Perry G, Smith MA. Ectopic expression of phospho-Smad2 in Alzheimer's disease: uncoupling of the transforming growth factor-beta pathway? J Neurosci Res. 2006 Dec; 84(8):1856-61. PMID: 16998902.
      Citations: 28     Fields:    Translation:HumansCells
    420. Zhu X, Babar A, Siedlak SL, Yang Q, Ito G, Iwatsubo T, Smith MA, Perry G, Chen SG. LRRK2 in Parkinson's disease and dementia with Lewy bodies. Mol Neurodegener. 2006 Nov 30; 1:17. PMID: 17137507.
      Citations: 19     Fields:    
    421. Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonz?lez JR, Gratac?s M, Huang J, Kalaitzopoulos D, Komura D, MacDonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME. Global variation in copy number in the human genome. Nature. 2006 Nov 23; 444(7118):444-54. PMID: 17122850.
      Citations: 1768     Fields:    Translation:Humans
    422. Fiegler H, Redon R, Andrews D, Scott C, Andrews R, Carder C, Clark R, Dovey O, Ellis P, Feuk L, French L, Hunt P, Kalaitzopoulos D, Larkin J, Montgomery L, Perry GH, Plumb BW, Porter K, Rigby RE, Rigler D, Valsesia A, Langford C, Humphray SJ, Scherer SW, Lee C, Hurles ME, Carter NP. Accurate and reliable high-throughput detection of copy number variation in the human genome. Genome Res. 2006 Dec; 16(12):1566-74. PMID: 17122085.
      Citations: 78     Fields:    Translation:HumansCells
    423. Zhu X, Siedlak SL, Smith MA, Perry G, Chen SG. LRRK2 protein is a component of Lewy bodies. Ann Neurol. 2006 Nov; 60(5):617-618. PMID: 16847950.
      Citations: 25     Fields:    Translation:HumansCells
    424. Zhu X, Lee HG, Perry G, Smith MA. Alzheimer disease, the two-hit hypothesis: an update. Biochim Biophys Acta. 2007 Apr; 1772(4):494-502. PMID: 17142016.
      Citations: 124     Fields:    Translation:Humans
    425. Lee HG, Ueda M, Miyamoto Y, Yoneda Y, Perry G, Smith MA, Zhu X. Aberrant localization of importin alpha1 in hippocampal neurons in Alzheimer disease. Brain Res. 2006 Dec 08; 1124(1):1-4. PMID: 17070506.
      Citations: 26     Fields:    Translation:HumansCells
    426. Webber KM, Casadesus G, Atwood CS, Bowen RL, Perry G, Smith MA. Gonadotropins: a cohesive gender-based etiology of Alzheimer disease. Mol Cell Endocrinol. 2007 Jan 02; 260-262:271-5. PMID: 17052835.
      Citations: 7     Fields:    Translation:Humans
    427. Webber KM, Stocco DM, Casadesus G, Bowen RL, Atwood CS, Previll LA, Harris PL, Zhu X, Perry G, Smith MA. Steroidogenic acute regulatory protein (StAR): evidence of gonadotropin-induced steroidogenesis in Alzheimer disease. Mol Neurodegener. 2006 Oct 03; 1:14. PMID: 17018137.
      Citations: 16     Fields:    
    428. Smith MA, Perry G. Commentary on "Perspective on a pathogenesis and treatment of Alzheimer's disease." Therapeutic strategies for Alzheimer's disease: the need for a new era of innovation. Alzheimers Dement. 2006 Oct; 2(4):294-5. PMID: 19595903.
      Citations:    Fields:    
    429. Previll LA, Crosby ME, Castellani RJ, Bowser R, Perry G, Smith MA, Zhu X. Increased expression of p130 in Alzheimer disease. Neurochem Res. 2007 Apr-May; 32(4-5):639-44. PMID: 17006760.
      Citations: 10     Fields:    Translation:HumansCells
    430. Lam-Himlin D, Espey MG, Perry G, Smith MA, Castellani RJ. Malignant glioma progression and nitric oxide. Neurochem Int. 2006 Dec; 49(8):764-8. PMID: 16971023.
      Citations: 20     Fields:    Translation:Humans
    431. Zhu X, Raina AK, Perry G, Smith MA. Apoptosis in Alzheimer disease: a mathematical improbability. Curr Alzheimer Res. 2006 Sep; 3(4):393-6. PMID: 17017869.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    432. Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose! Am J Pathol. 2006 Sep; 169(3):738-9. PMID: 16936250.
      Citations: 5     Fields:    Translation:HumansAnimalsPHPublic Health
    433. Liu G, Men P, Harris PL, Rolston RK, Perry G, Smith MA. Nanoparticle iron chelators: a new therapeutic approach in Alzheimer disease and other neurologic disorders associated with trace metal imbalance. Neurosci Lett. 2006 Oct 09; 406(3):189-93. PMID: 16919875.
      Citations: 41     Fields:    Translation:Humans
    434. Obrenovich ME, Smith MA, Siedlak SL, Chen SG, de la Torre JC, Perry G, Aliev G. Overexpression of GRK2 in Alzheimer disease and in a chronic hypoperfusion rat model is an early marker of brain mitochondrial lesions. Neurotox Res. 2006 Aug; 10(1):43-56. PMID: 17000469.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    435. Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA. Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol. 2006 Jul; 65(7):631-41. PMID: 16825950.
      Citations: 184     Fields:    Translation:HumansAnimalsCells
    436. Zhu X, Perry G, Moreira PI, Aliev G, Cash AD, Hirai K, Smith MA. Mitochondrial abnormalities and oxidative imbalance in Alzheimer disease. J Alzheimers Dis. 2006 Jul; 9(2):147-53. PMID: 16873962.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    437. Franco S, Blasco MA, Siedlak SL, Harris PL, Moreira PI, Perry G, Smith MA. Telomeres and telomerase in Alzheimer's disease: epiphenomena or a new focus for therapeutic strategy? Alzheimers Dement. 2006 Jul; 2(3):164-8. PMID: 19595878.
      Citations: 28     Fields:    
    438. Forero DA, Casadesus G, Perry G, Arboleda H. Synaptic dysfunction and oxidative stress in Alzheimer's disease: emerging mechanisms. J Cell Mol Med. 2006 Jul-Sep; 10(3):796-805. PMID: 16989739.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    439. Sparks DL, Friedland R, Petanceska S, Schreurs BG, Shi J, Perry G, Smith MA, Sharma A, Derosa S, Ziolkowski C, Stankovic G. Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology. J Nutr Health Aging. 2006 Jul-Aug; 10(4):247-54. PMID: 16886094.
      Citations: 40     Fields:    Translation:HumansAnimalsPHPublic Health
    440. Freeman JL, Perry GH, Feuk L, Redon R, McCarroll SA, Altshuler DM, Aburatani H, Jones KW, Tyler-Smith C, Hurles ME, Carter NP, Scherer SW, Lee C. Copy number variation: new insights in genome diversity. Genome Res. 2006 Aug; 16(8):949-61. PMID: 16809666.
      Citations: 321     Fields:    Translation:HumansAnimals
    441. Lee HG, Zhu X, Takeda A, Perry G, Smith MA. Emerging evidence for the neuroprotective role of alpha-synuclein. Exp Neurol. 2006 Jul; 200(1):1-7. PMID: 16780837.
      Citations: 8     Fields:    Translation:HumansAnimals
    442. Moreira PI, Zhu X, Nunomura A, Smith MA, Perry G. Therapeutic options in Alzheimer's disease. Expert Rev Neurother. 2006 Jun; 6(6):897-910. PMID: 16784412.
      Citations: 12     Fields:    Translation:Humans
    443. Aliev G, Miller JP, Leifer DW, Obrenovich ME, Shenk JC, Smith MA, Lamanna JC, Perry G, Lust DW, Cohen AR. Ultrastructural analysis of a murine model of congenital hydrocephalus produced by overexpression of transforming growth factor-beta1 in the central nervous system. J Submicrosc Cytol Pathol. 2006 Jun-Sep; 38(2-3):85-91. PMID: 17784635.
      Citations: 2     Fields:    Translation:AnimalsCells
    444. Smith MA, Zhu X, Lee HG, Harris PL, Fortino AE, Perry G, Castellani RJ. Sequestration of p27 within the cytoplasm of cardiac myocytes in chronic ischemic heart disease: pathogenic implications for ischemic cardiomyopathy. Age (Dordr). 2006 Mar; 28(1):85-91. PMID: 23598681.
      Citations:    Fields:    
    445. Perry GH, Tchinda J, McGrath SD, Zhang J, Picker SR, C?ceres AM, Iafrate AJ, Tyler-Smith C, Scherer SW, Eichler EE, Stone AC, Lee C. Hotspots for copy number variation in chimpanzees and humans. Proc Natl Acad Sci U S A. 2006 May 23; 103(21):8006-11. PMID: 16702545.
      Citations: 124     Fields:    Translation:HumansAnimalsCells
    446. Lee HG, Perry G, Zhu X, Nunomura A, Smith MA. Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression". Free Radic Biol Med. 2006 Jul 15; 41(2):188-9. PMID: 16814097.
      Citations: 1     Fields:    Translation:Humans
    447. Nunomura A, Castellani RJ, Lee HG, Moreira PI, Zhu X, Perry G, Smith MA. Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream. Sci Aging Knowledge Environ. 2006 May 03; 2006(8):pe10. PMID: 16672726.
      Citations: 8     Fields:    Translation:HumansCells
    448. Castellani RJ, Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Neuropathology of Alzheimer disease: pathognomonic but not pathogenic. Acta Neuropathol. 2006 Jun; 111(6):503-9. PMID: 16718346.
      Citations: 58     Fields:    Translation:Humans
    449. Hasegawa T, Matsuzaki-Kobayashi M, Takeda A, Sugeno N, Kikuchi A, Furukawa K, Perry G, Smith MA, Itoyama Y. Alpha-synuclein facilitates the toxicity of oxidized catechol metabolites: implications for selective neurodegeneration in Parkinson's disease. FEBS Lett. 2006 Apr 03; 580(8):2147-52. PMID: 16567160.
      Citations: 20     Fields:    Translation:HumansCells
    450. Moreira PI, Zhu X, Lee HG, Honda K, Smith MA, Perry G. The (un)balance between metabolic and oxidative abnormalities and cellular compensatory responses in Alzheimer disease. Mech Ageing Dev. 2006 Jun; 127(6):501-6. PMID: 16516950.
      Citations: 5     Fields:    Translation:HumansCells
    451. Castellani RJ, Lee HG, Perry G, Smith MA. Antioxidant protection and neurodegenerative disease: the role of amyloid-beta and tau. Am J Alzheimers Dis Other Demen. 2006 Mar-Apr; 21(2):126-30. PMID: 16634469.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    452. Strocchi P, Smith MA, Perry G, Tamagno E, Danni O, Pession A, Gaiba A, Dozza B. Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells. Neurobiol Aging. 2006 Nov; 27(11):1588-94. PMID: 16464517.
      Citations: 9     Fields:    Translation:HumansCells
    453. Lee HG, Zhu X, Nunomura A, Perry G, Smith MA. Amyloid beta: the alternate hypothesis. Curr Alzheimer Res. 2006 Feb; 3(1):75-80. PMID: 16472207.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    454. Moreira PI, Honda K, Zhu X, Nunomura A, Casadesus G, Smith MA, Perry G. Brain and brawn: parallels in oxidative strength. Neurology. 2006 Jan 24; 66(2 Suppl 1):S97-101. PMID: 16432155.
      Citations: 18     Fields:    Translation:HumansCells
    455. Zhu X, Lee HG, Moreira PI, Smith MA, Perry G. Presenilin mutation: a deadly first hit in Alzheimer disease. A commentary on "aging sensitizes towards ROS formation and lipid peroxidation in PS1M146L transgenic mice". Free Radic Biol Med. 2006 Mar 01; 40(5):737-9. PMID: 16520226.
      Citations:    Fields:    Translation:HumansAnimalsCells
    456. Lee HG, Zhu X, Perry G, Smith MA. The fallacy of amyloid and cognition in Alzheimer's disease. Drugs Aging. 2006; 23(2):179. PMID: 16536639.
      Citations:    Fields:    Translation:HumansAnimals
    457. Moreira PI, Zhu X, Liu Q, Honda K, Siedlak SL, Harris PL, Smith MA, Perry G. Compensatory responses induced by oxidative stress in Alzheimer disease. Biol Res. 2006; 39(1):7-13. PMID: 16629160.
      Citations: 14     Fields:    Translation:HumansCells
    458. Casadesus G, Garrett MR, Webber KM, Hartzler AW, Atwood CS, Perry G, Bowen RL, Smith MA. The estrogen myth: potential use of gonadotropin-releasing hormone agonists for the treatment of Alzheimer's disease. Drugs R D. 2006; 7(3):187-93. PMID: 16752944.
      Citations: 6     Fields:    Translation:Humans
    459. Perry G. Solving the insoluble. J Alzheimers Dis. 2006; 9(3 Suppl):301-4. PMID: 17004366.
      Citations: 3     Fields:    Translation:HumansCells
    460. Dwyer BE, Stone ML, Zhu X, Perry G, Smith MA. Heme deficiency in Alzheimer's disease: a possible connection to porphyria. J Biomed Biotechnol. 2006; 2006(3):24038. PMID: 17047301.
      Citations: 4     Fields:    
    461. Casadesus G, Puig ER, Webber KM, Atwood CS, Escuer MC, Bowen RL, Perry G, Smith MA. Targeting gonadotropins: an alternative option for Alzheimer disease treatment. J Biomed Biotechnol. 2006; 2006(3):39508. PMID: 17047306.
      Citations: 3     Fields:    
    462. Smith MA, Perry G, Zhu X, Haoudi A. Neurodegenerative diseases: mechanisms and therapies. J Biomed Biotechnol. 2006; 2006(3):47539. PMID: 17047307.
      Citations:    Fields:    
    463. Webber KM, Casadesus G, Zhu X, Obrenovich ME, Atwood CS, Perry G, Bowen RL, Smith MA. The cell cycle and hormonal fluxes in Alzheimer disease: a novel therapeutic target. Curr Pharm Des. 2006; 12(6):691-7. PMID: 16472159.
      Citations: 6     Fields:    Translation:HumansAnimals
    464. Nunomura A, Honda K, Takeda A, Hirai K, Zhu X, Smith MA, Perry G. Oxidative damage to RNA in neurodegenerative diseases. J Biomed Biotechnol. 2006; 2006(3):82323. PMID: 17047315.
      Citations: 46     Fields:    
    465. Perry GH, Verrelli BC, Stone AC. Molecular evolution of the primate developmental genes MSX1 and PAX9. Mol Biol Evol. 2006 Mar; 23(3):644-54. PMID: 16326750.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    466. Santa-Mar?a I, Hern?ndez F, Smith MA, Perry G, Avila J, Moreno FJ. Neurotoxic dopamine quinone facilitates the assembly of tau into fibrillar polymers. Mol Cell Biochem. 2005 Oct; 278(1-2):203-12. PMID: 16180106.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    467. Moreira PI, Honda K, Liu Q, Santos MS, Oliveira CR, Aliev G, Nunomura A, Zhu X, Smith MA, Perry G. Oxidative stress: the old enemy in Alzheimer's disease pathophysiology. Curr Alzheimer Res. 2005 Oct; 2(4):403-8. PMID: 16248845.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    468. Castellani RJ, Siedlak SL, Fortino AE, Perry G, Ghetti B, Smith MA. Chitin-like polysaccharides in Alzheimer's disease brains. Curr Alzheimer Res. 2005 Oct; 2(4):419-23. PMID: 16248847.
      Citations: 20     Fields:    Translation:HumansCells
    469. Webber KM, Raina AK, Marlatt MW, Zhu X, Prat MI, Morelli L, Casadesus G, Perry G, Smith MA. The cell cycle in Alzheimer disease: a unique target for neuropharmacology. Mech Ageing Dev. 2005 Oct; 126(10):1019-25. PMID: 15936057.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    470. Liu G, Garrett MR, Men P, Zhu X, Perry G, Smith MA. Nanoparticle and other metal chelation therapeutics in Alzheimer disease. Biochim Biophys Acta. 2005 Sep 25; 1741(3):246-52. PMID: 16051470.
      Citations: 38     Fields:    Translation:Humans
    471. Zhu X, Moreira PI, Smith MA, Perry G. Alzheimer's disease: an intracellular movement disorder? Trends Mol Med. 2005 Sep; 11(9):391-3. PMID: 16087404.
      Citations: 6     Fields:    Translation:Animals
    472. Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, Perry G. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathol. 2005 Sep; 110(3):232-8. PMID: 16096758.
      Citations: 24     Fields:    Translation:HumansCells
    473. Lin D, Lee HG, Liu Q, Perry G, Smith MA, Sayre LM. 4-Oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chem Res Toxicol. 2005 Aug; 18(8):1219-31. PMID: 16097795.
      Citations: 54     Fields:    Translation:HumansCells
    474. Dwyer BE, Takeda A, Zhu X, Perry G, Smith MA. Ferric cycle activity and Alzheimer disease. Curr Neurovasc Res. 2005 Jul; 2(3):261-7. PMID: 16181119.
      Citations: 2     Fields:    Translation:HumansAnimals
    475. Casadesus G, Smith MA, Perry G. Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, and Luigi Puglielli. Alzheimers Dement. 2005 Jul; 1(1):51-2. PMID: 19595817.
      Citations:    Fields:    
    476. Zhu X, Smith MA, Perry G, Wang Y, Ross AP, Zhao HW, Lamanna JC, Drew KL. MAPKs are differentially modulated in arctic ground squirrels during hibernation. J Neurosci Res. 2005 Jun 15; 80(6):862-8. PMID: 15884016.
      Citations: 18     Fields:    Translation:AnimalsCells