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Robert F. Hunter

Faculty RankProfessor
InstitutionUniversidad Central Del Caribe
DepartmentRetrovirus Research Center
AddressUniversidad Central del Caribe
Call Box 60-237
Bayamon PR 00960
Phone(787) 787-8710
Fax(787) 787-8722
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    Collapse Biography 
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    1977Alpha Omega Alpha

    Collapse Overview 
    Collapse overview
    As a formally trained Medical Oncologist with many years of experience in the evaluation and therapy of patients with HIV, HCV and malignant disorders, I have a commitment to accelerate the delivery of research advances to improve patient care in these catastrophic diseases. I believe that fostering and initiating translational research, participation in physician education and research mentoring is likely the best way I can do this. During my professional career I have been active in the education and mentoring of young students, internal medicine residents and researchers. I am actively involved with basic research on hematological conditions and the various immunodeficiency viruses. I am involved with clinical research in cancer and HIV infection and I have acquired the administrative and people skills necessary to manage research programs from a multidisciplinary point of view. My tenure as Chairman and Program Director of the Internal Medicine of our School of Medicine for 13 years, my role as Principal investigator of the Retrovirus Research Center for 18 years and co-Principal Investigator of the Puerto Rico Comprehensive Center for the Study of HIV Disparities (PR-CCHD), have given me the skills and knowledge to manage the complexities and details of multidisciplinary research programs and help to direct research initiatives. In 2007, I completed a master’s degree in Bioethics and I am one of the few clinicians and researchers in the Island to have formal advanced training in Bioethics. This training has been effectively used to mentor researchers in the area of the ethical conduct of research, as overseer of various DSMB programs and by providing our patients with the highest degree of protection from abuse.

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Cruz-Feliciano MA, Miranda-D?az C, Fern?ndez-Santos DM, Orobitg-Brenes D, Hunter-Mellado RF, Carri?n-Gonz?lez IS. Quality of life improvement in Latinas receiving combined substance use disorders and trauma-specific treatment: a cohort evaluation report. Health Qual Life Outcomes. 2017 May 02; 15(1):90. PMID: 28464830.
      Citations: 3     Fields:    Translation:Humans
    2. Tossas-Milligan KY, Hunter-Mellado RF, Mayor AM, Fern?ndez-Santos DM, Dworkin MS. Late HIV Testing in a Cohort of HIV-Infected Patients in Puerto Rico. P R Health Sci J. 2016 May 24; 35(2):113-121. PMID: 27232874.
      Citations: 1     Fields:    
    3. Mayor AM, Santiago-Rodriguez EJ, Rios-Olivares E, Tortolero-Luna G, Hunter-Mellado RF. Malignancies Trends in a Hispanic Cohort of HIV Persons in Puerto Rico before and after cART. Int J Cancer Res. 2016; 12(2):92-100. PMID: 27695577.
    4. Valderr?bano RJ, Blanco A, Santiago-Rodriguez EJ, Miranda C, Rivera-Del Rio Del Rio J, Ruiz J, Hunter R. Risk factors and clinical outcomes of arrhythmias in the medical intensive care unit. J Intensive Care. 2016; 4:9. PMID: 26807261.
    5. Fernandez-Santos DM, Miranda-Diaz C, Figueroa-Cosme WI, Ramon RO, Mayor AM, Rios-Olivares E, Hunter-Mellado RF. Impact of ASUMA Intervention on HIV Risk Behaviors among Puerto Rican Adolescents. Int J Environ Res Public Health. 2015 Dec 23; 13(1):ijerph13010060. PMID: 26703684.
      Citations:    Fields:    Translation:Humans
    6. Maldonado-Mart?nez G, Hunter-Mellado RF, Fern?ndez-Santos D, R?os-Olivares E. Persistent HIV Viremia: Description of a Cohort of HIV Infected Individuals with ART Failure in Puerto Rico. Int J Environ Res Public Health. 2015 Dec 22; 13(1):ijerph13010050. PMID: 26703691.
      Citations: 3     Fields:    Translation:Humans
    7. Santiago-Rodr?guez EJ, Mayor AM, Fern?ndez-Santos DM, Hunter-Mellado RF. Profile of HIV-Infected Hispanics with Pancytopenia. Int J Environ Res Public Health. 2015 Dec 22; 13(1):ijerph13010038. PMID: 26703689.
      Citations: 6     Fields:    Translation:Humans
    8. Miranda-Diaz C, Betancourt E, Ruiz-Candelaria Y, Hunter-Mellado RF. Barriers for Compliance to Breast, Colorectal, and Cervical Screening Cancer Tests among Hispanic Patients. Int J Environ Res Public Health. 2015 Dec 22; 13(1):ijerph13010021. PMID: 26703676.
      Citations: 19     Fields:    Translation:HumansPHPublic Health
    9. Tossas-Milligan KY, Hunter-Mellado RF, Mayor AM, Fern?ndez-Santos DM, Dworkin MS. Late HIV Testing in a Cohort of HIV-Infected Patients in Puerto Rico. P R Health Sci J. 2015 Sep; 34(3):148-54. PMID: 26356739.
      Citations: 2     Fields:    Translation:Humans
    10. Esponda OL, Hunter R, Del R?o JR, Washington AV. Levels of soluble TREM-like transcript 1 in patients presenting to the emergency department with chest pain. Clin Appl Thromb Hemost. 2015 Jan; 21(1):30-4. PMID: 25147325.
      Citations: 5     Fields:    Translation:HumansCells
    11. Santiago-Rodr?guez EJ, Mayor AM, Fern?ndez-Santos DM, Ruiz-Candelaria Y, Hunter-Mellado RF. Anemia in a cohort of HIV-infected Hispanics: prevalence, associated factors and impact on one-year mortality. BMC Res Notes. 2014 Jul 08; 7:439. PMID: 25005803.
      Citations: 14     Fields:    Translation:Humans
    12. Ruiz-Candelaria Y, Miranda-Diaz C, Hunter-Mellado RF. K-RAS mutation profile in Puerto Rican patients with colorectal cancer: trends from April 2009 to January 2011. Int J Biol Markers. 2013 Dec 17; 28(4):e393-7. PMID: 23999847.
      Citations: 2     Fields:    Translation:Humans
    13. Maldonado-Mart?nez G, Fern?ndez-Santos DM, R?os-Olivares E, Mayor AM, Hunter-Mellado RF. HIV/AIDS in the Puerto Rican elderly: immunological changes between gender and body mass index. J Health Care Poor Underserved. 2013 Nov; 24(4 Suppl):94-105. PMID: 24241264.
      Citations: 2     Fields:    Translation:Humans
    14. Mayor AM, Fern?ndez DM, Col?n H, Thomas JC, Miranda C, Hunter-Mellado RF. Hepatitis-C multimedia prevention program in poor Hispanic HIV-infected injecting drug users: six months after intervention. J Health Care Poor Underserved. 2013 Nov; 24(4 Suppl):29-37. PMID: 24241258.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    15. Dworkin MS, Peterson CE, Gao W, Mayor A, Hunter R, Negron E, Fleury A, Besch CL. Efficacy of a food safety comic book on knowledge and self-reported behavior for persons living with AIDS. PLoS One. 2013; 8(10):e72874. PMID: 24124447.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    16. Hanna DB, Buchacz K, Gebo KA, Hessol NA, Horberg MA, Jacobson LP, Kirk GD, Kitahata MM, Korthuis PT, Moore RD, Napravnik S, Patel P, Silverberg MJ, Sterling TR, Willig JH, Lau B, Althoff KN, Crane HM, Collier AC, Samji H, Thorne JE, Gill MJ, Klein MB, Martin JN, Rodriguez B, Rourke SB, Gange SJ. Trends and disparities in antiretroviral therapy initiation and virologic suppression among newly treatment-eligible HIV-infected individuals in North America, 2001-2009. Clin Infect Dis. 2013 Apr; 56(8):1174-82. PMID: 23315317.
      Citations: 67     Fields:    Translation:Humans
    17. Dworkin MS, Peterson CE, Gao W, Mayor A, Hunter R, Negron E, Fleury A, Besch CL. Food Safety Knowledge, Beliefs and Behavior of Persons with AIDS: A Multicenter Study. Food Prot Trends. 2013 Jan 01; 33(1):32-41. PMID: 25061438.
    18. Koenig SP, Rodriguez LA, Bartholomew C, Edwards A, Carmichael TE, Barrow G, Cabi? A, Hunter R, Vasquez-Mora G, Quava-Jones A, Adomakoh N, Peter Figueroa J, Liautaud B, Torres M, Pape JW. Long-term antiretroviral treatment outcomes in seven countries in the Caribbean. J Acquir Immune Defic Syndr. 2012 Apr 01; 59(4):e60-71. PMID: 22240464.
      Citations: 22     Fields:    Translation:Humans
    19. Mayor, A., Ruiz, Y., Fernández, D., Hunter, R. HIV/AIDS Associated Malignant Disorders: Role of Highly Active Antiretroviral Therapy. Immunosuppression-Role in Health and Diseases. 2012; 433-456.
    20. Mayor AM, Fern?ndez Santos DM, Dworkin MS, R?os-Olivares E, Hunter-Mellado RF. Toxoplasmic encephalitis in an AIDS cohort at Puerto Rico before and after highly active antiretroviral therapy (HAART). Am J Trop Med Hyg. 2011 May; 84(5):838-41. PMID: 21540399.
      Citations: 9     Fields:    Translation:Humans
    21. Gomez LR, Mellado RH. Late presentation of familial mediterranean fever: a case report. Bol Asoc Med P R. 2010 Jul-Sep; 102(3):69-71. PMID: 23875524.
      Citations:    Fields:    Translation:Humans
    22. Benitez L, Vila S, Mellado RH. Hidden in plain sight: macrophage activation syndrome complicating Adult Onset Still's Disease. Bol Asoc Med P R. 2010 Jul-Sep; 102(3):79-82. PMID: 23875527.
      Citations:    Fields:    Translation:Humans
    23. P?rez-Mercado AE, Maldonado-Mart?nez G, del Rio JR, Mellado RF. Cardiovascular events during general elections in Bayamon, Puerto Rico. Bol Asoc Med P R. 2010 Jul-Sep; 102(3):28-31. PMID: 23875518.
      Citations:    Fields:    Translation:Humans
    24. Miranda C, Fernandez DM, Ramon RO, Vel?zquez M, Mayor AM, Hunter-Mellado RF. Changes in the socio-demographics, risk behaviors, clinical and immunological profile of a cohort of the Puerto Rican population living with HIV: an update of the Retrovirus Research Center (1992-2008). Bol Asoc Med P R. 2010 Jul-Sep; 102(3):45-51. PMID: 23875520.
      Citations: 1     Fields:    Translation:Humans
    25. Morales J, Villa K, Gattis J, Castro W, Colon K, Lubkowski J, Sanabria P, Hunter R, Washington AV. Soluble TLT-1 modulates platelet-endothelial cell interactions and actin polymerization. Blood Coagul Fibrinolysis. 2010 Apr; 21(3):229-36. PMID: 20093931.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    26. Fern?ndez Santos DM, Figueroa-Cosme WI, G?mez Mde L, Maysonet-Cruz J, Miranda-D?az C, Sept?lveda-Santiago M, R?os-Olivares E, Hunter-Mellado RF. Changes in developmental factors and HIV risk behaviors among early adolescents in Puerto Rico. Ethn Dis. 2010; 20(1 Suppl 1):S1-122-6. PMID: 20521399.
      Citations: 1     Fields:    Translation:Humans
    27. Mayor AM, Fern?ndez DM, Col?n HM, Thomas JC, Hunter-Mellado RE. The effectiveness evaluation of a multimedia hepatitis C prevention program for Hispanic HIV-infected individuals. Ethn Dis. 2010; 20(1 Suppl 1):S1-158-62. PMID: 20521407.
      Citations: 1     Fields:    Translation:Humans
    28. Mayor AM, Dworkin M, Quesada L, R?os-Olivares E, Hunter-Mellado RF. The morbidity and mortality associated with kidney disease in an HIV-infected cohort in Puerto Rico. Ethn Dis. 2010; 20(1 Suppl 1):S1-163-7. PMID: 20521408.
      Citations: 4     Fields:    Translation:Humans
    29. Ram?rez-Marrero FA, De Jes?s E, Santana-Bagur J, Hunter R, Frontera W, Joyner MJ. Prevalence of cardiometabolic risk factors in Hispanics living with HIV. Ethn Dis. 2010; 20(4):423-8. PMID: 21305832.
      Citations: 8     Fields:    Translation:Humans
    30. Washington AV, Gibot S, Acevedo I, Gattis J, Quigley L, Feltz R, De La Mota A, Schubert RL, Gomez-Rodriguez J, Cheng J, Dutra A, Pak E, Chertov O, Rivera L, Morales J, Lubkowski J, Hunter R, Schwartzberg PL, McVicar DW. TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans. J Clin Invest. 2009 Jun; 119(6):1489-501. PMID: 19436112.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    31. Quintana-Ortiz RA, Gomez MA, B?ez Feliciano DV, Hunter-Mellado RF. Suicide attempts among Puerto Rican men and women with HIV/AIDS: a study of prevalence and risk factors. Ethn Dis. 2008; 18(2 Suppl 2):S2-219-24. PMID: 18646353.
      Citations: 12     Fields:    Translation:Humans
    32. Cruz-Amy M, Serrano J, Labrador I, Hernandez D, Fernandez DM, Quintana R, Hunter-Mellado RF. Changes in profile and colorectal cancer stage over 15 years in Puerto Rico. Ethn Dis. 2008; 18(2 Suppl 2):S2-128-31. PMID: 18646334.
      Citations:    Fields:    Translation:Humans
    33. B?ez Feliciano DV, G?mez MA, Fern?ndez-Santos DM, Quintana R, Rios-Olivares E, Hunter-Mellado RF. Profile of Puerto Rican HIV/AIDS patients with early and non-early initiation of injection drug use. Ethn Dis. 2008; 18(2 Suppl 2):S2-99-104. PMID: 18646329.
      Citations: 6     Fields:    Translation:Humans
    34. Mayor AM, G?mez MA, R?os-Olivares E, Hunter-Mellado RF. AIDS-defining neoplasm prevalence in a cohort of HIV-infected patients, before and after highly active antiretroviral therapy. Ethn Dis. 2008; 18(2 Suppl 2):S2-189-94. PMID: 18646347.
      Citations: 5     Fields:    Translation:Humans
    35. Mayor AM, Fern?ndez DM, Col?n HM, Thomas JC, Hunter-Mellado RF. The feasibility and acceptability of a multimedia hepatitis C prevention program for Hispanic HIV-infected persons. Ethn Dis. 2008; 18(2 Suppl 2):S2-195-9. PMID: 18646348.
      Citations: 3     Fields:    Translation:Humans
    36. Fern?ndez DM, Figueroa WI, G?mez Mde L, Maysonet J, Olivares ER, Hunter RF. Changes in HIV/AIDS knowledge among early adolescents in Puerto Rico. Ethn Dis. 2008; 18(2 Suppl 2):S2-146-50. PMID: 18646338.
      Citations: 6     Fields:    Translation:Humans
    37. Rodríguez, J.W., Rodríguez, L.A., Font, G., Nieves, K., Cubano, L.A., Boukli, N., Otero, M., Hunter, R., Nair, M.P., and Ríos-Olivares, E. . Co-Expression of Apoptosis-Related Molecules on Activated CD8+CD38+ T-Cells is Associated with HIV-1 Disease Progression. American Journal of Infectious Disease. 2007; 4(3):208-216.
    38. Rodr?guez JW, Pagan NO, Ocasio MC, R?os Z, Cubano LA, Boukli NM, Otero M, Hunter R, Nair MP, Rios-Olivares E. Induction of a Soluble Anti-HIV-1 factor (s) with IFN-?, IL-10, and ?-Chemokine Modulating Activity by an Influenza-Bacterial Polyantigenic Mixture. Am J Infect Dis. 2007; 3(4). PMID: 24327810.
    39. B?ez-Feliciano DV, Quintana R, G?mez MA, Fern?ndez DM, Vel?zquez M, Olivares E, Le?n Valiente C, Mayor AM, Hunter-Mellado RF. Trends in the HIV and AIDS epidemic in a Puerto Rican cohort of patients: 1992-2005. Bol Asoc Med P R. 2006 Jul-Sep; 98(3):174-83. PMID: 19610556.
      Citations: 5     Fields:    Translation:Humans
    40. Cruz-Amy M, Hunter-Mellado R. Factor V Leiden thrombophilia: presentation of three patients and a literature review. Bol Asoc Med P R. 2006 Jul-Sep; 98(3):213-21. PMID: 19610561.
      Citations:    Fields:    Translation:Humans
    41. Giron J, Perez Blair E, Hunter Mellado R. A clinico-pathologic presentation of a 23-year old-female with lymphangioleiomyomatosis and Wilm's tumor. Bol Asoc Med P R. 2006 Jul-Sep; 98(3):196-202. PMID: 19610558.
      Citations:    Fields:    Translation:Humans
    42. Mayor AM, Gomez MA, Fernandez DM, Rios-Olivares E, Thomas JC, Hunter RF. Morbidity and mortality profile of human immunodeficiency virus-infected patients with and without hepatitis C co-infection. Am J Trop Med Hyg. 2006 Feb; 74(2):239-45. PMID: 16474077.
      Citations: 7     Fields:    Translation:HumansCells
    43. Mayor AM, Gomez MA, Fernandez DM, Rios-Olivares E, Thomas JC, Hunter RF. Morbidity and mortality profile of human immunodeficiency virus-infected patients with and without hepatitis C co-infection. 2006; 74(2)(Am J Trop ):239-45.
    44. B?ez-Feliciano DV, Thomas JC, G?mez MA, Miranda S, Fern?ndez DM, Vel?zquez M, R?os-Olivares E, Hunter-Mellado RF. Changes in the AIDS epidemiologic situation in Puerto Rico following health care reform and the introduction of HAART. Rev Panam Salud Publica. 2005 Feb; 17(2):92-101. PMID: 15826386.
      Citations: 6     Fields:    Translation:Humans
    45. Fern?ndez DM, G?mez Mde L, Figueroa W, Vel?zquez M, B?ez DV, R?os-Olivares E, Hunter RF. A comparison of the sociodemographic, risk-behavior, and substance-abuse profile of young vs older HIV-infected Puerto Rican patients. Ethn Dis. 2005; 15(4 Suppl 5):S5-25-9. PMID: 16315378.
      Citations: 4     Fields:    Translation:Humans
    46. Mayor AM, G?mez MA, R?os-Oliveras E, Hunter-Mellado RF. Mortality trends of HIV-infected patients after the introduction of highly active antiretroviral therapy: analysis of a cohort of 3,322 HIV-infected persons. Ethn Dis. 2005; 15(4 Suppl 5):S5-57-62. PMID: 16312941.
      Citations: 10     Fields:    Translation:Humans
    47. Rodríguez, J.W., Figueroa, W.I., Pérez-Casanova, A.E., Machado, M. Pagán, N.O., Ríos, Z., García, O., Cubano, L.A., Alonso, O., Hunter, R., Ríos-Olivares, E. . Immunological Dynomics of CD8+ T-lympocytes During HIV Infection and Its Association with Disease Progression. Immunology. 2004; 215-221.
    48. Hunter Mellado RF, Negron J, Gomez MA. A strategic supportive model for health prevention in the elderly: profile of a Puerto Rican geriatric population in a public health sector. Bol Asoc Med P R. 1997 Jul-Sep; 89(7-9):102-10. PMID: 9419927.
      Citations:    Fields:    Translation:HumansPHPublic HealthCTClinical Trials
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