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Zivar Yousefipour

Faculty RankProfessor
InstitutionTexas Southern University
DepartmentCollege of Pharmacy and Health Science
Address3100 Cleburn
Houston TX 77004
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    Dr. Zivar Yousefipour is an Associate Professor at the College of Pharmacy and Health Sciences at Texas Southern University. Dr. Yousefipour received her Bachelor of Science in Biology and Masters of Science in Biochemistry from University of Houston. She finished her PhD in Environmental Toxicology from Texas Southern University in 2004. Dr. Yousefipour has extensive research experience in cardiovascular diseases that includes studies focusing on effect of environmental pollutants on cardiovascular system, mechanism of acute renal filature, role of sodium transporters in salt-induced hypertension, and the aging process. Dr. Yousefipour maintains a research laboratory in COPHS studying the mechanism of acrolein-induced toxicity of vascular system. She has been the recipient of several awards including 2005 Caroline Tum Sudan Professional Opportunity Award from American Physiological Society. As the result of her work, Dr. Yousefipour has authored or co-authored 15 scientific papers in prominent journals and 27 presentations at national and international meetings. Dr. Yousefipour has been a member of several professional organizations including American Heart Association, American Physiological Society, and Society of Toxicology. Dr. Yousefipour's research has been supported by a SC3 grant from NIH/NIGMS since 2014.

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    SC3GM103746     (YOUSEFIPOUR, ZIVAR)Aug 1, 2013 - Jul 31, 2019
    Molecular Mechanism of Acrolein-Induced Vascular Toxicity: Role of PPAR gamma and
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ranganna K, Selvam C, Shivachar A, Yousefipour Z. Histone Deacetylase Inhibitors as Multitarget-Directed Epi-Drugs in Blocking PI3K Oncogenic Signaling: A Polypharmacology Approach. Int J Mol Sci. 2020 Nov 02; 21(21). PMID: 33147762.
      Citations:    Fields:    
    2. Mathew OP, Ranganna K, Mathew J, Zhu M, Yousefipour Z, Selvam C, Milton SG. Cellular Effects of Butyrate on Vascular Smooth Muscle Cells are Mediated through Disparate Actions on Dual Targets, Histone Deacetylase (HDAC) Activity and PI3K/Akt Signaling Network. Int J Mol Sci. 2019 Jun 14; 20(12). PMID: 31197106.
      Citations: 1     Fields:    Translation:AnimalsCells
    3. Yousefipour Z, Chug N, Marek K, Nesbary A, Mathew J, Ranganna K, Newaz MA. Contribution of PPAR? in modulation of acrolein-induced inflammatory signaling in gp91phox knock-out mice. Biochem Cell Biol. 2017 08; 95(4):482-490. PMID: 28376311.
      Citations:    Fields:    Translation:AnimalsCells
    4. Arshadniya I, Ranganna K, Yousefipour Z. Int J Complement Alt Med. A Case Report of the At-Home Application of Maggot in Treatment of Infected Wound in A Diabetic Patient. 2017; 8(1):00250.
    5. Kasturi Ranganna, Omana P. Mathew, Chelliah Selvam, and Zivar Yousefipour. Atherosclerotic Cardiovascular Disease. Epigenetic DNA Methylation Alteration in the Pathogenesis of Atherosclerosis. 2017. View Publication.
    6. Shirlette G. Milton, Omana P. Mathew, Kasturi Ranganna, Zivar Yousefipour and Mohammad Newaz. British Journal of Pharmaceutical Research. Acrolein-induced Vascular Smooth Muscle Cells (VSMC) Cytotoxicity: Differential Effects of N-Acetylcysteine and Ebselen. 2015; 5(8):1 - 17.
    7. Yousefipour Z, Newaz M. PPARa ligand clofibrate ameliorates blood pressure and vascular reactivity in spontaneously hypertensive rats. Acta Pharmacol Sin. 2014 Apr; 35(4):476-82. PMID: 24562305.
      Citations: 4     Fields:    Translation:AnimalsCells
    8. Newaz M, Yousefipour Z. PPAR? and NAD(P)H oxidase system interaction in glycerol-induced acute renal failure: role of gp91phox subunit of NAD(P)H oxidase. Ren Fail. 2014 May; 36(4):567-74. PMID: 24479849.
      Citations:    Fields:    Translation:AnimalsCells
    9. Yousefipour Z, Zhang C, Monfareed M, Walker J, Newaz M. Acrolein-induced oxidative stress in NAD(P)H Oxidase Subunit gp91phox knock-out mice and its modulation of NF?B and CD36. J Health Care Poor Underserved. 2013 Nov; 24(4 Suppl):118-31. PMID: 24241266.
      Citations: 2     Fields:    Translation:Animals
    10. Newaz M, Yousefipour Z. Acrolein-induced inflammatory signaling in vascular smooth muscle cells requires activation of serum response factor (SRF) and NF?B. J Basic Clin Physiol Pharmacol. 2013; 24(4):287-97. PMID: 23893683.
      Citations: 2     Fields:    Translation:AnimalsCells
    11. Yousefipour Z, Oyekan A, Newaz M. Interaction of oxidative stress, nitric oxide and peroxisome proliferator activated receptor gamma in acute renal failure. Pharmacol Ther. 2010 Mar; 125(3):436-45. PMID: 20117134.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    12. Newaz M, Yousefipour Z, Oyekan A. Natriuretic and renoprotective effect of chronic oral neutral endopeptidase inhibition in acute renal failure. Ren Fail. 2010 Jan; 32(3):384-90. PMID: 20370457.
      Citations: 2     Fields:    Translation:Animals
    13. Yousefipour Z, Oyekan A, Newaz M. Role of G protein-coupled receptor kinase-2 in peroxisome proliferator-activated receptor gamma-mediated modulation of blood pressure and renal vascular reactivity in SHR. Am J Nephrol. 2009; 30(3):201-8. PMID: 19420904.
      Citations: 1     Fields:    Translation:Animals
    14. Ranganna K, Mathew OP, Yatsu FM, Yousefipour Z, Hayes BE, Milton SG. Involvement of glutathione/glutathione S-transferase antioxidant system in butyrate-inhibited vascular smooth muscle cell proliferation. FEBS J. 2007 Nov; 274(22):5962-78. PMID: 17961182.
      Citations: 11     Fields:    Translation:AnimalsCells
    15. Yousefipour Z, Hercule H, Truong L, Oyekan A, Newaz M. Ciglitazone, a peroxisome proliferator-activated receptor gamma inducer, ameliorates renal preglomerular production and activity of angiotensin II and thromboxane A2 in glycerol-induced acute renal failure. J Pharmacol Exp Ther. 2007 Aug; 322(2):461-8. PMID: 17494862.
      Citations: 4     Fields:    Translation:Animals
    16. Yousefipour Z, Hercule H, Oyekan AO, Newaz MA. Antioxidant U74389G improves glycerol-induced acute renal failure without affecting PPARgamma gene. Ren Fail. 2007; 29(7):903-10. PMID: 17994460.
      Citations:    Fields:    Translation:Animals
    17. Newaz MA, Yousefipour Z, Oyekan A. Oxidative stress-associated vascular aging is xanthine oxidase-dependent but not NAD(P)H oxidase-dependent. J Cardiovasc Pharmacol. 2006 Sep; 48(3):88-94. PMID: 17031261.
      Citations: 13     Fields:    Translation:Animals
    18. Newaz M, Yousefipour Z, Oyekan A. Role of PPAR-gamma on the pathogenesis and vascular changes in glycerol-induced acute renal failure. Pharmacol Res. 2006 Sep; 54(3):234-40. PMID: 16820301.
      Citations: 4     Fields:    Translation:AnimalsCells
    19. Yousefipour Z, Ranganna K, Newaz MA, Milton SG. Mechanism of acrolein-induced vascular toxicity. J Physiol Pharmacol. 2005 Sep; 56(3):337-53. PMID: 16204758.
      Citations: 11     Fields:    Translation:AnimalsCells
    20. Newaz MA, Yousefipour Z, Nawal NN. Modulation of nitric oxide synthase activity in brain, liver, and blood vessels of spontaneously hypertensive rats by ascorbic acid: protection from free radical injury. Clin Exp Hypertens. 2005 Aug; 27(6):497-508. PMID: 16081342.
      Citations: 8     Fields:    Translation:Animals
    21. Ranganna K, Yousefipour Z, Yatsu FM, Milton SG, Hayes BE. Gene expression profile of butyrate-inhibited vascular smooth muscle cell proliferation. Mol Cell Biochem. 2003 Dec; 254(1-2):21-36. PMID: 14674679.
      Citations: 14     Fields:    Translation:AnimalsCells
    22. Newaz MA, Yousefipour Z, Nawal N, Adeeb N. Nitric oxide synthase activity in blood vessels of spontaneously hypertensive rats: antioxidant protection by gamma-tocotrienol. J Physiol Pharmacol. 2003 Sep; 54(3):319-27. PMID: 14566071.
      Citations: 13     Fields:    Translation:Animals
    23. Newaz MA, Yousefipour Z, Hercule H, Truong L, Oyekan A. Chronic endopeptidase inhibition in DOCA-salt hypertension: mechanism of cardiovascular protection. Clin Exp Hypertens. 2003 Aug; 25(6):335-47. PMID: 12940471.
      Citations:    Fields:    Translation:Animals
    24. Ranganna K, Yousefipour Z, Nasif R, Yatsu FM, Milton SG, Hayes BE. Acrolein activates mitogen-activated protein kinase signal transduction pathways in rat vascular smooth muscle cells. Mol Cell Biochem. 2002 Nov; 240(1-2):83-98. PMID: 12487375.
      Citations: 14     Fields:    Translation:AnimalsCells
    25. Newaz MA, Yousefipour Z, Oyekan A. Effects of pergolide on blood pressure and tissue injury in DOCA-salt hypertension. Blood Press. 2002; 11(2):110-5. PMID: 12035871.
      Citations:    Fields:    Translation:Animals
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