"Nodal Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The founding member of the nodal signaling ligand family of proteins. Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. It is expressed asymmetrically on the left side in chordates and plays a critical role in the genesis of left-right asymmetry during vertebrate development.
| Descriptor ID |
D055457
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| MeSH Number(s) |
D12.644.276.954.550.650 D12.776.467.942.550.650 D23.529.942.550.650
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Nodal Protein".
Below are MeSH descriptors whose meaning is more specific than "Nodal Protein".
This graph shows the total number of publications written about "Nodal Protein" by people in this website by year, and whether "Nodal Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nodal Protein" by people in Profiles.
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Vo BT, Cody B, Cao Y, Khan SA. Differential role of Sloan-Kettering Institute (Ski) protein in Nodal and transforming growth factor-beta (TGF-?)-induced Smad signaling in prostate cancer cells. Carcinogenesis. 2012 Nov; 33(11):2054-64.
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Vo BT, Khan SA. Expression of nodal and nodal receptors in prostate stem cells and prostate cancer cells: autocrine effects on cell proliferation and migration. Prostate. 2011 Jul; 71(10):1084-96.
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Adkins HB, Bianco C, Schiffer SG, Rayhorn P, Zafari M, Cheung AE, Orozco O, Olson D, De Luca A, Chen LL, Miatkowski K, Benjamin C, Normanno N, Williams KP, Jarpe M, LePage D, Salomon D, Sanicola M. Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo. J Clin Invest. 2003 Aug; 112(4):575-87.