Bone Morphogenetic Protein 4
"Bone Morphogenetic Protein 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bone morphogenetic protein that is a potent inducer of bone formation. It also functions as a regulator of MESODERM formation during EMBRYONIC DEVELOPMENT.
| Descriptor ID |
D055415
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| MeSH Number(s) |
D12.644.276.954.200.400 D12.776.467.942.200.400 D23.529.942.200.400
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Bone Morphogenetic Protein 4".
Below are MeSH descriptors whose meaning is more specific than "Bone Morphogenetic Protein 4".
This graph shows the total number of publications written about "Bone Morphogenetic Protein 4" by people in this website by year, and whether "Bone Morphogenetic Protein 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Bone Morphogenetic Protein 4" by people in Profiles.
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Simonds MM, Schlefman AR, McCahan SM, Sullivan KE, Rose CD, Brescia AMC. The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes. Pediatr Rheumatol Online J. 2021 May 12; 19(1):72.
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Simonds MM, Schlefman AR, McCahan SM, Sullivan KE, Rose CD, Brescia AC. Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation. Pediatr Rheumatol Online J. 2020 Nov 16; 18(1):89.
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De Vilder EYG, Cardoen S, Hosen MJ, Le Saux O, De Zaeytijd J, Leroy BP, De Reuck J, Coucke PJ, De Paepe A, Hemelsoet D, Vanakker OM. Pathogenic variants in the ABCC6 gene are associated with an increased risk for ischemic stroke. Brain Pathol. 2018 11; 28(6):822-831.
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Kupfer SS, Skol AD, Hong E, Ludvik A, Kittles RA, Keku TO, Sandler RS, Ellis NA. Shared and independent colorectal cancer risk alleles in TGF?-related genes in African and European Americans. Carcinogenesis. 2014 Sep; 35(9):2025-30.
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Mercier F, Douet V. Bone morphogenetic protein-4 inhibits adult neurogenesis and is regulated by fractone-associated heparan sulfates in the subventricular zone. J Chem Neuroanat. 2014 May; 57-58:54-61.
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Marikawa Y, Tamashiro DA, Fujita TC, Alarcon VB. Dual roles of Oct4 in the maintenance of mouse P19 embryonal carcinoma cells: as negative regulator of Wnt/?-catenin signaling and competence provider for Brachyury induction. Stem Cells Dev. 2011 Apr; 20(4):621-33.
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Graham TR, Odero-Marah VA, Chung LW, Agrawal KC, Davis R, Abdel-Mageed AB. PI3K/Akt-dependent transcriptional regulation and activation of BMP-2-Smad signaling by NF-kappaB in metastatic prostate cancer cells. Prostate. 2009 Feb 01; 69(2):168-80.
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Abdel-Hakeem AK, Henry TQ, Magee TR, Desai M, Ross MG, Mansano RZ, Torday JS, Nast CC. Mechanisms of impaired nephrogenesis with fetal growth restriction: altered renal transcription and growth factor expression. Am J Obstet Gynecol. 2008 Sep; 199(3):252.e1-7.
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Vogt RR, Unda R, Yeh LC, Vidro EK, Lee JC, Tsin AT. Bone morphogenetic protein-4 enhances vascular endothelial growth factor secretion by human retinal pigment epithelial cells. J Cell Biochem. 2006 Aug 01; 98(5):1196-202.
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Zhang Z, Zhang X, Avniel WA, Song Y, Jones SM, Jones TA, Fermin C, Chen Y. Malleal processus brevis is dispensable for normal hearing in mice. Dev Dyn. 2003 May; 227(1):69-77.