Papillomavirus E7 Proteins
"Papillomavirus E7 Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
ONCOGENE PROTEINS from papillomavirus that deregulate the CELL CYCLE of infected cells and lead to NEOPLASTIC CELL TRANSFORMATION. Papillomavirus E7 proteins have been shown to interact with various regulators of the cell cycle including RETINOBLASTOMA PROTEIN and certain cyclin-dependent kinase inhibitors.
| Descriptor ID |
D050725
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| MeSH Number(s) |
D12.776.624.664.520.420
|
| Concept/Terms |
Papillomavirus E7 Proteins- Papillomavirus E7 Proteins
- E7 Proteins, Papillomavirus
- E7 Oncogene Proteins
- Oncogene Proteins, E7
- Oncogene Protein E7, Papillomavirus
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Below are MeSH descriptors whose meaning is more general than "Papillomavirus E7 Proteins".
Below are MeSH descriptors whose meaning is more specific than "Papillomavirus E7 Proteins".
This graph shows the total number of publications written about "Papillomavirus E7 Proteins" by people in this website by year, and whether "Papillomavirus E7 Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 4 | 4 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Papillomavirus E7 Proteins" by people in Profiles.
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Li M, McGhee EM, Shinno L, Lee K, Lin YL. Exposure to Microbial Metabolite Butyrate Prolongs the Survival Time and Changes the Growth Pattern of Human Papillomavirus 16 E6/E7-Immortalized Keratinocytes in?Vivo. Am J Pathol. 2021 10; 191(10):1822-1836.
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Peng S, Wang JW, Karanam B, Wang C, Huh WK, Alvarez RD, Pai SI, Hung CF, Wu TC, Roden RB. Sequential cisplatin therapy and vaccination with HPV16 E6E7L2 fusion protein in saponin adjuvant GPI-0100 for the treatment of a model HPV16+ cancer. PLoS One. 2015; 10(1):e116389.
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Leitz J, Reuschenbach M, Lohrey C, Honegger A, Accardi R, Tommasino M, Llano M, von Knebel Doeberitz M, Hoppe-Seyler K, Hoppe-Seyler F. Oncogenic human papillomaviruses activate the tumor-associated lens epithelial-derived growth factor (LEDGF) gene. PLoS Pathog. 2014 Mar; 10(3):e1003957.
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Karanam B, Gambhira R, Peng S, Jagu S, Kim DJ, Ketner GW, Stern PL, Adams RJ, Roden RB. Vaccination with HPV16 L2E6E7 fusion protein in GPI-0100 adjuvant elicits protective humoral and cell-mediated immunity. Vaccine. 2009 Feb 11; 27(7):1040-9.
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Kim D, Gambhira R, Karanam B, Monie A, Hung CF, Roden R, Wu TC. Generation and characterization of a preventive and therapeutic HPV DNA vaccine. Vaccine. 2008 Jan 17; 26(3):351-60.
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Tang X, Zhang Q, Nishitani J, Brown J, Shi S, Le AD. Overexpression of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1 alpha protein accumulation and vascular endothelial growth factor expression in human cervical carcinoma cells. Clin Cancer Res. 2007 May 01; 13(9):2568-76.
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Sarkar AK, Tortolero-Luna G, Follen M, Sastry KJ. Inverse correlation of cellular immune responses specific to synthetic peptides from the E6 and E7 oncoproteins of HPV-16 with recurrence of cervical intraepithelial neoplasia in a cross-sectional study. Gynecol Oncol. 2005 Dec; 99(3 Suppl 1):S251-61.
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Yuan H, Fu F, Zhuo J, Wang W, Nishitani J, An DS, Chen IS, Liu X. Human papillomavirus type 16 E6 and E7 oncoproteins upregulate c-IAP2 gene expression and confer resistance to apoptosis. Oncogene. 2005 Jul 28; 24(32):5069-78.
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B?ez A, Cantor A, Fonseca S, Marcos-Martinez M, Mathews LA, Muro-Cacho CA, Mu?oz-Antonia T. Differences in Smad4 expression in human papillomavirus type 16-positive and human papillomavirus type 16-negative head and neck squamous cell carcinoma. Clin Cancer Res. 2005 May 01; 11(9):3191-7.
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Swan DC, Rajeevan M, Tortolero-Luna G, Follen M, Tucker RA, Unger ER. Human papillomavirus type 16 E2 and E6/E7 variants. Gynecol Oncol. 2005 Mar; 96(3):695-700.