Insulin-Secreting Cells

"Insulin-Secreting Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A type of pancreatic cell representing about 50-80% of the islet cells. Beta cells secrete INSULIN.

Descriptor ID	D050417
MeSH Number(s)	A03.734.414.131 A06.390.131 A06.407.414.087 A11.382.625.092 A11.436.294.092
Concept/Terms	Insulin-Secreting Cells Insulin-Secreting Cells Cell, Insulin-Secreting Cells, Insulin-Secreting Insulin Secreting Cells Insulin-Secreting Cell beta Cells, Pancreatic Pancreatic beta Cell beta Cell, Pancreatic Pancreatic B Cells B Cell, Pancreatic B Cells, Pancreatic Pancreatic B Cell Pancreatic beta Cells

Below are MeSH descriptors whose meaning is more general than "Insulin-Secreting Cells".

Anatomy [A]
Digestive System [A03]
Pancreas [A03.734]
Islets of Langerhans [A03.734.414]
Insulin-Secreting Cells [A03.734.414.131]
Endocrine System [A06]
Enteroendocrine Cells [A06.390]
Insulin-Secreting Cells [A06.390.131]
Endocrine Glands [A06.407]
Islets of Langerhans [A06.407.414]
Insulin-Secreting Cells [A06.407.414.087]
Cells [A11]
Endocrine Cells [A11.382]
Enteroendocrine Cells [A11.382.625]
Insulin-Secreting Cells [A11.382.625.092]
Epithelial Cells [A11.436]
Enteroendocrine Cells [A11.436.294]
Insulin-Secreting Cells [A11.436.294.092]

Below are MeSH descriptors whose meaning is related to "Insulin-Secreting Cells".

Below are MeSH descriptors whose meaning is more specific than "Insulin-Secreting Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Insulin-Secreting Cells" by people in this website by year, and whether "Insulin-Secreting Cells" was a major or minor topic of these publications.

Bar chart showing 23 publications over 14 distinct years, with a maximum of 6 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2006	1	0	1
2008	1	0	1
2009	1	1	2
2010	1	0	1
2011	1	0	1
2012	1	0	1
2014	2	0	2
2015	4	2	6
2019	0	1	1
2021	1	0	1
2023	3	0	3
2025	1	0	1
2026	0	1	1

Below are the most recent publications written about "Insulin-Secreting Cells" by people in Profiles.

Hansen MS, Hill CJ, Sussel L, Wells KL. Optimizing Single-Cell Long-Read Sequencing for Enhanced Isoform Detection in Pancreatic Islets. Diabetes. 2026 Apr 01; 75(4):606-616.

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Wortham M, Ramms B, Zeng C, Benthuysen JR, Sai S, Pollow DP, Liu F, Schlichting M, Harrington AR, Liu B, Prakash TP, Pirie EC, Zhu H, Baghdasarian S, Lee ST, Ruthig VA, Wells KL, Auwerx J, Shirihai OS, Sander M. The protein deacetylase SIRT2 exerts metabolic control over adaptive ? cell proliferation. J Clin Invest. 2025 Oct 01; 135(19).

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Moss ND, Wells KL, Theis A, Kim YK, Spigelman AF, Liu X, MacDonald PE, Sussel L. Modulation of insulin secretion by RBFOX2-mediated alternative splicing. Nat Commun. 2023 11 25; 14(1):7732.

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Abarinov V, Levine JA, Churchill AJ, Hopwood B, Deiter CS, Guney MA, Wells KL, Schrunk JM, Guo Y, Hammelman J, Gifford DK, Magnuson MA, Wichterle H, Sussel L. Major ? cell-specific functions of NKX2.2 are mediated via the NK2-specific domain. Genes Dev. 2023 06 01; 37(11-12):490-504.

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Alhazzaa RA, McKinley RE, Getachew B, Tizabi Y, Heinbockel T, Csoka AB. Epigenetic Changes Induced by High Glucose in Human Pancreatic Beta Cells. J Diabetes Res. 2023; 2023:9947294.

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Zhou AX, Mondal T, Tabish AM, Abadpour S, Ericson E, Smith DM, Kn?ll R, Scholz H, Kanduri C, Tyrberg B, Althage M. The long noncoding RNA TUNAR modulates Wnt signaling and regulates human ?-cell proliferation. Am J Physiol Endocrinol Metab. 2021 04 01; 320(4):E846-E857.

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Guardado-Mendoza R, Salazar-L?pez SS, ?lvarez-Canales M, Farf?n-V?zquez D, Mart?nez-L?pez YE, Jim?nez-Ceja LM, Su?rez-P?rez EL, Angulo-Romero F, Evia-Viscarra ML, Montes de Oca-Loyola ML, Dur?n-P?rez EG, Folli F, Aguilar-Garc?a A. The combination of linagliptin, metformin and lifestyle modification to prevent type 2 diabetes (PRELLIM). A randomized clinical trial. Metabolism. 2020 03; 104:154054.

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Adeyemo AA, Zaghloul NA, Chen G, Doumatey AP, Leitch CC, Hostelley TL, Nesmith JE, Zhou J, Bentley AR, Shriner D, Fasanmade O, Okafor G, Eghan B, Agyenim-Boateng K, Chandrasekharappa S, Adeleye J, Balogun W, Owusu S, Amoah A, Acheampong J, Johnson T, Oli J, Adebamowo C, Collins F, Dunston G, Rotimi CN. ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. Nat Commun. 2019 07 19; 10(1):3195.

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Keaton JM, Hellwege JN, Ng MCY, Palmer ND, Pankow JS, Fornage M, Wilson JG, Correa A, Rasmussen-Torvik LJ, Rotter JI, Chen YI, Taylor KD, Rich SS, Wagenknecht LE, Freedman BI, Bowden DW. GENOME-WIDE INTERACTION WITH SELECTED TYPE 2 DIABETES LOCI REVEALS NOVEL LOCI FOR TYPE 2 DIABETES IN AFRICAN AMERICANS. Pac Symp Biocomput. 2017; 22:242-253.

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Joseph JJ, Echouffo-Tcheugui JB, Kalyani RR, Yeh HC, Bertoni AG, Effoe VS, Casanova R, Sims M, Correa A, Wu WC, Wand GS, Golden SH. Aldosterone, Renin, and Diabetes Mellitus in African Americans: The Jackson Heart Study. J Clin Endocrinol Metab. 2016 04; 101(4):1770-8.

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