Cleavage And Polyadenylation Specificity Factor
"Cleavage And Polyadenylation Specificity Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An RNA-binding protein that recognizes the AAUAAA RNA SEQUENCE at the 3' end of MRNA. It contains four subunits of 30, 73, 100 and 160 kDa molecular size and combines with CLEAVAGE STIMULATION FACTOR to form a stable complex with mRNA that directs the 3' cleavage and polyadenylation reaction.
| Descriptor ID |
D039223
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| MeSH Number(s) |
D12.776.157.725.124.240 D12.776.664.962.444.240
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cleavage And Polyadenylation Specificity Factor".
Below are MeSH descriptors whose meaning is more specific than "Cleavage And Polyadenylation Specificity Factor".
This graph shows the total number of publications written about "Cleavage And Polyadenylation Specificity Factor" by people in this website by year, and whether "Cleavage And Polyadenylation Specificity Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cleavage And Polyadenylation Specificity Factor" by people in Profiles.
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Hao S, Zhang L, Zhao D, Zhou J, Ye C, Qu H, Li QQ. Inhibitor AN3661 reveals biological functions of Arabidopsis CLEAVAGE and POLYADENYLATION SPECIFICITY FACTOR 73. Plant Physiol. 2023 08 31; 193(1):537-554.
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Yu Z, Lin J, Li QQ. Transcriptome Analyses of FY Mutants Reveal Its Role in mRNA Alternative Polyadenylation. Plant Cell. 2019 10; 31(10):2332-2352.
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Lin J, Xu R, Wu X, Shen Y, Li QQ. Role of cleavage and polyadenylation specificity factor 100: anchoring poly(A) sites and modulating transcription termination. Plant J. 2017 Sep; 91(5):829-839.
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Zhao H, Ye X, Li QQ. Characterization of plant polyadenylation complexes by using tandem affinity purification. Methods Mol Biol. 2015; 1255:69-78.
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Liu M, Xu R, Merrill C, Hong L, Von Lanken C, Hunt AG, Li QQ. Integration of developmental and environmental signals via a polyadenylation factor in Arabidopsis. PLoS One. 2014; 9(12):e115779.
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Zhao H, Xing D, Li QQ. Unique features of plant cleavage and polyadenylation specificity factor revealed by proteomic studies. Plant Physiol. 2009 Nov; 151(3):1546-56.
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Zhang J, Addepalli B, Yun KY, Hunt AG, Xu R, Rao S, Li QQ, Falcone DL. A polyadenylation factor subunit implicated in regulating oxidative signaling in Arabidopsis thaliana. PLoS One. 2008 Jun 11; 3(6):e2410.
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Xu R, Zhao H, Dinkins RD, Cheng X, Carberry G, Li QQ. The 73 kD subunit of the cleavage and polyadenylation specificity factor (CPSF) complex affects reproductive development in Arabidopsis. Plant Mol Biol. 2006 Jul; 61(4-5):799-815.