Spectrometry, Mass, Electrospray Ionization
"Spectrometry, Mass, Electrospray Ionization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometry technique used for analysis of nonvolatile compounds such as proteins and macromolecules. The technique involves preparing electrically charged droplets from analyte molecules dissolved in solvent. The electrically charged droplets enter a vacuum chamber where the solvent is evaporated. Evaporation of solvent reduces the droplet size, thereby increasing the coulombic repulsion within the droplet. As the charged droplets get smaller, the excess charge within them causes them to disintegrate and release analyte molecules. The volatilized analyte molecules are then analyzed by mass spectrometry.
| Descriptor ID |
D021241
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| MeSH Number(s) |
E05.196.566.600
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Electrospray Ionization".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Electrospray Ionization".
This graph shows the total number of publications written about "Spectrometry, Mass, Electrospray Ionization" by people in this website by year, and whether "Spectrometry, Mass, Electrospray Ionization" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2003 | 0 | 4 | 4 |
| 2004 | 4 | 7 | 11 |
| 2005 | 4 | 6 | 10 |
| 2006 | 1 | 6 | 7 |
| 2007 | 2 | 8 | 10 |
| 2008 | 5 | 9 | 14 |
| 2009 | 1 | 8 | 9 |
| 2010 | 0 | 2 | 2 |
| 2011 | 2 | 7 | 9 |
| 2012 | 1 | 2 | 3 |
| 2013 | 2 | 6 | 8 |
| 2014 | 2 | 6 | 8 |
| 2015 | 1 | 3 | 4 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 2 | 3 |
| 2019 | 0 | 2 | 2 |
| 2020 | 1 | 2 | 3 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spectrometry, Mass, Electrospray Ionization" by people in Profiles.
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Sarkar M, Ma J, Tapadar S, Caggia S, Oyelere AK, Khan SA, Xie H. Development and validation of a sensitive LC-MS/MS assay of GT-14, a novel Gai2 inhibitor, in rat plasma, and its application in pharmacokinetic study. J Pharm Biomed Anal. 2024 Aug 01; 245:116183.
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Wang M, Liao X, Tchounwou PB, Liu YM. Coupling a droplet generator with conventional ESI-MS for quantitative analysis of small-volume samples. Anal Bioanal Chem. 2022 Feb; 414(5):1809-1817.
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Li X, Liao X, Liu YM. A microfluidic platform integrating paper adsorption-based sample clean-up and voltage-assisted liquid desorption electrospray ionization mass spectrometry for biological sample analysis. Talanta. 2020 Sep 01; 217:121106.
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Franke AA, Li X, Dabalos C, Lai JF. Improved oxytocin analysis from human serum and urine by orbitrap ESI-LC-HRAM-MS. Drug Test Anal. 2020 Jun; 12(6):846-852.
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Li X, Zhao J, Xu R, Pan L, Liu YM. Mass spectrometric quantification of microRNAs in biological samples based on multistage signal amplification. Analyst. 2020 Mar 07; 145(5):1783-1788.
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Zhang JH, Mottamal M, Jin HS, Guo S, Gu Y, Wang G, Zhao LM. Design, synthesis and evaluation of belinostat analogs as histone deacetylase inhibitors. Future Med Chem. 2019 11; 11(21):2765-2778.
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Akula HK, Lakshman MK. Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H-Benzotriazol-1-yloxy-tris(dimethyl-amino)phosphonium Hexafluorophosphate. Curr Protoc Nucleic Acid Chem. 2019 03; 76(1):e73.
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Li X, Rout P, Xu R, Pan L, Tchounwou PB, Ma Y, Liu YM. Quantification of MicroRNAs by Coupling Cyclic Enzymatic Amplification with Microfluidic Voltage-Assisted Liquid Desorption Electrospray Ionization Mass Spectrometry. Anal Chem. 2018 11 20; 90(22):13663-13669.
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Ravindran K, Sivaramakrishnan S, Hussain M, Dash CK, Bamisile BS, Qasim M, Liande W. Investigation and molecular docking studies of Bassianolide from Lecanicillium lecanii against Plutella xylostella (Lepidoptera: Plutellidae). Comp Biochem Physiol C Toxicol Pharmacol. 2018 Apr; 206-207:65-72.
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Black DM, Robles G, Lopez P, Bach SBH, Alvarez M, Whetten RL. Liquid Chromatography Separation and Mass Spectrometry Detection of Silver-Lipoate Ag29(LA)12 Nanoclusters: Evidence of Isomerism in the Solution Phase. Anal Chem. 2018 02 06; 90(3):2010-2017.