Peptide Elongation Factor 2
"Peptide Elongation Factor 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptide Elongation Factor 2 catalyzes the translocation of peptidyl-tRNA from the A site to the P site of eukaryotic ribosomes by a process linked to the hydrolysis of GTP to GDP.
| Descriptor ID |
D020652
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| MeSH Number(s) |
D08.811.277.040.330.300.100.102 D12.776.157.325.150.102 D12.776.835.700.350.102
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Peptide Elongation Factor 2".
Below are MeSH descriptors whose meaning is more specific than "Peptide Elongation Factor 2".
This graph shows the total number of publications written about "Peptide Elongation Factor 2" by people in this website by year, and whether "Peptide Elongation Factor 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Peptide Elongation Factor 2" by people in Profiles.
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Piserchio A, Isiorho EA, Dalby KN, Ghose R. Structure of the complex between calmodulin and a functional construct of eukaryotic elongation factor 2 kinase bound to an ATP-competitive inhibitor. J Biol Chem. 2023 06; 299(6):104813.
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Piserchio A, Long KJ, Browning LS, Bohanon AL, Isiorho EA, Dalby KN, Ghose R. ADP enhances the allosteric activation of eukaryotic elongation factor 2 kinase by?calmodulin. Proc Natl Acad Sci U S A. 2023 04 25; 120(17):e2300902120.
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Piserchio A, Will N, Giles DH, Hajredini F, Dalby KN, Ghose R. Solution Structure of the Carboxy-Terminal Tandem Repeat Domain of Eukaryotic Elongation Factor 2 Kinase and Its Role in Substrate Recognition. J Mol Biol. 2019 07 12; 431(15):2700-2717.
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Lim EJ, Kim CW. Functional characterization of the promoter region of the chicken elongation factor-2 gene. Gene. 2007 Jan 15; 386(1-2):183-90.
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Connell SR, Trieber CA, Dinos GP, Einfeldt E, Taylor DE, Nierhaus KH. Mechanism of Tet(O)-mediated tetracycline resistance. EMBO J. 2003 Feb 17; 22(4):945-53.