"Endothelin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63)
| Descriptor ID |
D019332
|
| MeSH Number(s) |
D12.644.276.400.225 D12.776.467.400.225 D23.529.400.225
|
| Concept/Terms |
Proendothelin (1-38)- Proendothelin (1-38)
- Big Endothelin
- Big Endothelin-1
- Big Endothelin 1
- Endothelin-1, Big
- Endothelin, Big
Preproendothelin-1- Preproendothelin-1
- Preproendothelin 1
- Preproendothelin
- Proendothelin-1 Precursor
- Precursor, Proendothelin-1
- Proendothelin 1 Precursor
|
Below are MeSH descriptors whose meaning is more general than "Endothelin-1".
Below are MeSH descriptors whose meaning is more specific than "Endothelin-1".
This graph shows the total number of publications written about "Endothelin-1" by people in this website by year, and whether "Endothelin-1" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 1 | 3 |
| 2001 | 1 | 0 | 1 |
| 2002 | 6 | 2 | 8 |
| 2003 | 0 | 2 | 2 |
| 2004 | 3 | 1 | 4 |
| 2005 | 2 | 2 | 4 |
| 2006 | 6 | 3 | 9 |
| 2007 | 3 | 0 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 2 | 3 |
| 2010 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 1 | 3 |
| 2020 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Endothelin-1" by people in Profiles.
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Castro VL, Reyes-Nava NG, Sanchez BB, Gonzalez CG, Paz D, Quintana AM. Activation of WNT signaling restores the facial deficits in a zebrafish with defects in cholesterol metabolism. Genesis. 2020 12; 58(12):e23397.
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Rebholz CM, Harman JL, Grams ME, Correa A, Shimbo D, Coresh J, Young BA. Association between Endothelin-1 Levels and Kidney Disease among Blacks. J Am Soc Nephrol. 2017 Nov; 28(11):3337-3344.
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Chung S, Dwabe S, Elshimali Y, Sukhija H, Aroh C, Vadgama JV. Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array. PLoS One. 2015; 10(8):e0134948.
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Calder?n-Garcidue?as L, Franco-Lira M, D'Angiulli A, Rodr?guez-D?az J, Blaurock-Busch E, Busch Y, Chao CK, Thompson C, Mukherjee PS, Torres-Jard?n R, Perry G. Mexico City normal weight children exposed to high concentrations of ambient PM2.5 show high blood leptin and endothelin-1, vitamin D deficiency, and food reward hormone dysregulation versus low pollution controls. Relevance for obesity and Alzheimer disease. Environ Res. 2015 Jul; 140:579-92.
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Altieri PI, Marcial JM, Banchs HL, Escobales N, Crespo M, Gonz?lez W. Coronary levels of angiotensin-II and endothelin-I in diabetic patients with and without coronary artery disease. Bol Asoc Med P R. 2015 Jan-Mar; 107(1):5-7.
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Gregoski MJ, Buxbaum SG, Kapuku G, Dong Y, Zhu H, Davis M, Gonto K, Treiber FA. Interactive influences of ethnicity, endothelin-1 gene, and everyday discrimination upon nocturnal ambulatory blood pressure. Ann Behav Med. 2013 Jun; 45(3):377-86.
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Deliu E, Brailoiu GC, Mallilankaraman K, Wang H, Madesh M, Undieh AS, Koch WJ, Brailoiu E. Intracellular endothelin type B receptor-driven Ca2+ signal elicits nitric oxide production in endothelial cells. J Biol Chem. 2012 Nov 30; 287(49):41023-31.
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Rajapurohitam V, Kilic A, Javadov S, Karmazyn M. Role of NF-?B and p38 MAPK activation in mediating angiotensin II and endothelin-1-induced stimulation in leptin production and cardiomyocyte hypertrophy. Mol Cell Biochem. 2012 Jul; 366(1-2):287-97.
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Newaz M, Yousefipour Z, Oyekan A. Natriuretic and renoprotective effect of chronic oral neutral endopeptidase inhibition in acute renal failure. Ren Fail. 2010 Jan; 32(3):384-90.
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Hunter JC, Zeidan A, Javadov S, Kilic A, Rajapurohitam V, Karmazyn M. Nitric oxide inhibits endothelin-1-induced neonatal cardiomyocyte hypertrophy via a RhoA-ROCK-dependent pathway. J Mol Cell Cardiol. 2009 Dec; 47(6):810-8.