"Endothelins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
21-Amino-acid peptides produced by vascular endothelial cells and functioning as potent vasoconstrictors. The endothelin family consists of three members, ENDOTHELIN-1; ENDOTHELIN-2; and ENDOTHELIN-3. All three peptides contain 21 amino acids, but vary in amino acid composition. The three peptides produce vasoconstrictor and pressor responses in various parts of the body. However, the quantitative profiles of the pharmacological activities are considerably different among the three isopeptides.
| Descriptor ID |
D016232
|
| MeSH Number(s) |
D12.644.276.400 D12.776.467.400 D23.529.400
|
| Concept/Terms |
Endothelins- Endothelins
- Endothelium-Derived Vasoconstrictor Factors
- Vasoconstrictor Factors, Endothelium-Derived
- Endothelin
|
Below are MeSH descriptors whose meaning is more general than "Endothelins".
Below are MeSH descriptors whose meaning is more specific than "Endothelins".
This graph shows the total number of publications written about "Endothelins" by people in this website by year, and whether "Endothelins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Endothelins" by people in Profiles.
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Fernandes VFL, Macaspac C, Lu L, Yoshizawa M. Evolution of the developmental plasticity and a coupling between left mechanosensory neuromasts and an adaptive foraging behavior. Dev Biol. 2018 09 15; 441(2):262-271.
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Eiland E, Nzerue C, Faulkner M. Preeclampsia 2012. J Pregnancy. 2012; 2012:586578.
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Schorlemmer A, Matter ML, Shohet RV. Cardioprotective signaling by endothelin. Trends Cardiovasc Med. 2008 Oct; 18(7):233-9.
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Yakubu MA, Liliom K, Tigyi GJ, Leffler CW. Role of lysophosphatidic acid in endothelin-1- and hematoma-induced alteration of cerebral microcirculation. Am J Physiol. 1997 Aug; 273(2 Pt 2):R703-9.
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Yakubu MA, Shibata M, Leffler CW. Hematoma-induced enhanced cerebral vasoconstrictions to leukotriene C4 and endothelin-1 in piglets: role of prostanoids. Pediatr Res. 1995 Jul; 38(1):119-23.
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Yakubu MA, Shibata M, Leffler CW. Subarachnoid hematoma attenuates vasodilation and potentiates vasoconstriction induced by vasoactive agents in newborn pigs. Pediatr Res. 1994 Nov; 36(5):589-94.