Neuroprotective Agents

"Neuroprotective Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids.

Descriptor ID	D018696
MeSH Number(s)	D27.505.696.706.548 D27.505.954.427.575
Concept/Terms	Neuroprotective Agents Neuroprotective Agents Agents, Neuroprotective Neuroprotectants Neuroprotective Drugs Drugs, Neuroprotective Neuroprotective Effect Neuroprotective Effect Effect, Neuroprotective Neuroprotective Effects Effects, Neuroprotective

Below are MeSH descriptors whose meaning is more general than "Neuroprotective Agents".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Physiological Effects of Drugs [D27.505.696]
Protective Agents [D27.505.696.706]
Neuroprotective Agents [D27.505.696.706.548]
Therapeutic Uses [D27.505.954]
Central Nervous System Agents [D27.505.954.427]
Neuroprotective Agents [D27.505.954.427.575]

Below are MeSH descriptors whose meaning is more specific than "Neuroprotective Agents".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Neuroprotective Agents" by people in this website by year, and whether "Neuroprotective Agents" was a major or minor topic of these publications.

Bar chart showing 172 publications over 23 distinct years, with a maximum of 16 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	1	0	1
2001	0	1	1
2002	5	1	6
2003	6	3	9
2004	2	3	5
2005	4	4	8
2006	5	5	10
2007	4	1	5
2008	7	2	9
2009	5	1	6
2010	6	3	9
2011	10	1	11
2012	5	2	7
2013	7	3	10
2014	11	2	13
2015	9	1	10
2016	1	2	3
2017	12	4	16
2018	6	1	7
2019	5	2	7
2020	6	1	7
2021	6	0	6
2022	6	0	6

Below are the most recent publications written about "Neuroprotective Agents" by people in Profiles.

Getachew B, Csoka AB, Copeland RL, Manaye KF, Tizabi Y. Dihydromyricetin Protects Against Salsolinol-Induced Toxicity in Dopaminergic Cell Line: Implication for Parkinson's Disease. Neurotox Res. 2023 Apr; 41(2):141-148.

View in: PubMed
Ferrer-Acosta Y, Rodriguez-Mass? S, P?rez D, Eterovic VA, Ferchmin PA, Martins AH. Memantine has a nicotinic neuroprotective pathway in acute hippocampal slices after an NMDA insult. Toxicol In Vitro. 2022 Oct; 84:105453.

View in: PubMed
Evans JA, Mendonca P, Soliman KFA. Neuroprotective Effects and Therapeutic Potential of the Citrus Flavonoid Hesperetin in Neurodegenerative Diseases. Nutrients. 2022 May 26; 14(11).

View in: PubMed
Payne A, Nahashon S, Taka E, Adinew GM, Soliman KFA. Epigallocatechin-3-Gallate (EGCG): New Therapeutic Perspectives for Neuroprotection, Aging, and Neuroinflammation for the Modern Age. Biomolecules. 2022 02 25; 12(3).

View in: PubMed
Yu S, Doycheva DM, Gamdzyk M, Gao Y, Guo Y, Travis ZD, Tang J, Chen WX, Zhang JH. BMS-470539 Attenuates Oxidative Stress and Neuronal Apoptosis via MC1R/cAMP/PKA/Nurr1 Signaling Pathway in a Neonatal Hypoxic-Ischemic Rat Model. Oxid Med Cell Longev. 2022; 2022:4054938.

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Chen WN, Shaikh MF, Bhuvanendran S, Date A, Ansari MT, Radhakrishnan AK, Othman I. Poloxamer 188 (P188), A Potential Polymeric Protective Agent for Central Nervous System Disorders: A Systematic Review. Curr Neuropharmacol. 2022; 20(4):799-808.

View in: PubMed
Getachew B, Csoka AB, Garden AR, Copeland RL, Tizabi Y. Sodium Butyrate Protects Against Ethanol-Induced Toxicity in SH-SY5Y Cell Line. Neurotox Res. 2021 Dec; 39(6):2186-2193.

View in: PubMed
He M, Kittur FS, Hung CY, Zhang J, Jing L, Sane DC, Li PA, Xie J. A Novel Plant-Produced Asialo-rhuEPO Protects Brain from Ischemic Damage Without Erythropoietic Action. Transl Stroke Res. 2022 04; 13(2):338-354.

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Ilesanmi OB, Akinmoladun AC, Elusiyan CA, Ogungbe IV, Olugbade TA, Olaleye MT. Neuroprotective flavonoids of the leaf of Antiaris africana Englea against cyanide toxicity. J Ethnopharmacol. 2022 Jan 10; 282:114592.

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Huang Y, Guo Y, Huang L, Fang Y, Li D, Liu R, Lu Q, Ren R, Tang L, Lian L, Hu Y, Tang J, Chen G, Zhang JH. Kisspeptin-54 attenuates oxidative stress and neuronal apoptosis in early brain injury after subarachnoid hemorrhage in rats via GPR54/ARRB2/AKT/GSK3? signaling pathway. Free Radic Biol Med. 2021 08 01; 171:99-111.

View in: PubMed

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