"Dextran Sulfate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
| Descriptor ID |
D016264
|
| MeSH Number(s) |
D09.698.365.272.300
|
| Concept/Terms |
Dextran Sulfate Sodium- Dextran Sulfate Sodium
- Sulfate Sodium, Dextran
- Sodium Dextran Sulfate
- Dextran Sulfate, Sodium
- Sulfate, Sodium Dextran
|
Below are MeSH descriptors whose meaning is more general than "Dextran Sulfate".
Below are MeSH descriptors whose meaning is more specific than "Dextran Sulfate".
This graph shows the total number of publications written about "Dextran Sulfate" by people in this website by year, and whether "Dextran Sulfate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 1 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
| 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dextran Sulfate" by people in Profiles.
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Zhu HT, Luo J, Peng Y, Cheng XF, Wu SZ, Zhao YD, Chang L, Sun ZJ, Dong DL. Nitazoxanide protects against experimental ulcerative colitis through improving intestinal barrier and inhibiting inflammation. Chem Biol Interact. 2024 May 25; 395:111013.
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Mesas C, Mart?nez R, Doello K, Ortiz R, L?pez-Jurado M, Berm?dez F, Qui?onero F, Prados J, Porres JM, Melguizo C. In vivo antitumor activity of Euphorbia lathyris ethanol extract in colon cancer models. Biomed Pharmacother. 2022 May; 149:112883.
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Singh G, Haileselassie Y, Ji AR, Maecker HT, Sinha SR, Brim H, Habtezion A, Ashktorab H. Protective Effect of Saffron in Mouse Colitis Models Through Immune Modulation. Dig Dis Sci. 2022 07; 67(7):2922-2935.
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Banskota S, Brim H, Kwon YH, Singh G, Sinha SR, Wang H, Khan WI, Ashktorab H. Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice. Molecules. 2021 Jun 02; 26(11).
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Parnell EA, Walch EM, Lo DD. Inducible Colonic M Cells Are Dependent on TNFR2 but Not Lt?r, Identifying Distinct Signalling Requirements for Constitutive Versus Inducible M Cells. J Crohns Colitis. 2017 Jun 01; 11(6):751-760.
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Zhu C, Ling Q, Cai Z, Wang Y, Zhang Y, Hoffmann PR, Zheng W, Zhou T, Huang Z. Selenium-Containing Phycocyanin from Se-Enriched Spirulina platensis Reduces Inflammation in Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-?B Activation. J Agric Food Chem. 2016 Jun 22; 64(24):5060-70.
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Shukla PK, Chaudhry KK, Mir H, Gangwar R, Yadav N, Manda B, Meena AS, Rao R. Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. BMC Cancer. 2016 Mar 07; 16:189.
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Bennett KM, Parnell EA, Sanscartier C, Parks S, Chen G, Nair MG, Lo DD. Induction of Colonic M Cells during Intestinal Inflammation. Am J Pathol. 2016 05; 186(5):1166-79.
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Rose AH, Huang Z, Mafnas C, Hara JH, Hoffmann FW, Hashimoto AS, Bertino P, Hoffmann PR. Calpain-2 Inhibitor Therapy Reduces Murine Colitis and Colitis-associated Cancer. Inflamm Bowel Dis. 2015 Sep; 21(9):2005-15.
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Ogunwobi OO, Beales IL. The role of adiponectin in colitis. Gastroenterology. 2007 Mar; 132(3):1199-200; author reply 1200-1.