HIV Envelope Protein gp120

"HIV Envelope Protein gp120" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kDa and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens, most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.

Descriptor ID	D015699
MeSH Number(s)	D12.776.964.775.325.164.249 D12.776.964.775.562.500.500 D12.776.964.970.880.325.164.249 D23.050.327.520.350
Concept/Terms	HIV Envelope Protein gp120 HIV Envelope Protein gp120 Envelope Glycoprotein gp120, HIV gp120 Envelope Glycoprotein, HIV HIV Envelope Glycoprotein gp120 HTLV-III gp120 HTLV III gp120 gp120, HTLV-III env Protein gp120, HIV gp120(HIV)

Below are MeSH descriptors whose meaning is more general than "HIV Envelope Protein gp120".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Viral Proteins [D12.776.964]
Retroviridae Proteins [D12.776.964.775]
Gene Products, env [D12.776.964.775.325]
env Gene Products, Human Immunodeficiency Virus [D12.776.964.775.325.164]
HIV Envelope Protein gp120 [D12.776.964.775.325.164.249]
Human Immunodeficiency Virus Proteins [D12.776.964.775.562]
env Gene Products, Human Immunodeficiency Virus [D12.776.964.775.562.500]
HIV Envelope Protein gp120 [D12.776.964.775.562.500.500]
Viral Structural Proteins [D12.776.964.970]
Viral Envelope Proteins [D12.776.964.970.880]
Gene Products, env [D12.776.964.970.880.325]
env Gene Products, Human Immunodeficiency Virus [D12.776.964.970.880.325.164]
HIV Envelope Protein gp120 [D12.776.964.970.880.325.164.249]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Viral [D23.050.327]
HIV Antigens [D23.050.327.520]
HIV Envelope Protein gp120 [D23.050.327.520.350]

Below are MeSH descriptors whose meaning is related to "HIV Envelope Protein gp120".

Below are MeSH descriptors whose meaning is more specific than "HIV Envelope Protein gp120".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "HIV Envelope Protein gp120" by people in this website by year, and whether "HIV Envelope Protein gp120" was a major or minor topic of these publications.

Bar chart showing 38 publications over 21 distinct years, with a maximum of 5 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	1	2
1997	1	0	1
1998	0	1	1
1999	2	0	2
2000	1	1	2
2001	1	0	1
2002	1	3	4
2003	0	1	1
2004	2	0	2
2005	1	0	1
2006	1	1	2
2008	0	1	1
2009	2	0	2
2011	4	0	4
2013	4	1	5
2014	1	0	1
2015	1	0	1
2016	0	1	1
2017	0	1	1
2023	0	2	2
2025	0	1	1

Below are the most recent publications written about "HIV Envelope Protein gp120" by people in Profiles.

Coleman MI, Khan MB, Gbodossou E, Diop A, DeBarros K, Bond VC, Floyd V, Kondwani K, Rice VM, Powell MD. Plant Lectin, MoMo30, Pressures HIV-1 to Select for Variants with Deleted N-Linked Glycosylation Sites. Viruses. 2025 06 27; 17(7).

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Ogundiran AI, Chang T-L, Ivanov A, Kumari N, Nekhai S, Chandran PL. Shear-reversible clusters of HIV-1 in solution: stabilized by antibodies, dispersed by mucin. J Virol. 2023 10 31; 97(10):e0075223.

View in: PubMed
Khan M, Diop A, Gbodossou E, Xiao P, Coleman M, De Barros K, Duong H, Bond VC, Floyd V, Kondwani K, Rice VM, Harris-Hooker S, Villinger F, Powell MD. Anti-human immunodeficiency virus-1 activity of MoMo30 protein isolated from the traditional African medicinal plant Momordica balsamina. Virol J. 2023 03 22; 20(1):50.

View in: PubMed
Hu G, Yelamanchili S, Kashanchi F, Haughey N, Bond VC, Witwer KW, Pulliam L, Buch S. Proceedings of the 2017 ISEV symposium on "HIV, NeuroHIV, drug abuse, & EVs". J Neurovirol. 2017 Dec; 23(6):935-940.

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Reid WC, Ibrahim WG, Kim SJ, Denaro F, Casas R, Lee DE, Maric D, Hammoud DA. Characterization of neuropathology in the HIV-1 transgenic rat at different ages. J Neuroimmunol. 2016 Mar 15; 292:116-25.

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Melendez RI, Roman C, Capo-Velez CM, Lasalde-Dominicci JA. Decreased glial and synaptic glutamate uptake in the striatum of HIV-1 gp120 transgenic mice. J Neurovirol. 2016 06; 22(3):358-65.

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Ramos FM, Delgado-V?lez M, Ortiz ?L, B?ez-Pag?n CA, Quesada O, Lasalde-Dominicci JA. Expression of CHRFAM7A and CHRNA7 in neuronal cells and postmortem brain of HIV-infected patients: considerations for HIV-associated neurocognitive disorder. J Neurovirol. 2016 06; 22(3):327-35.

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Pandhare J, Dash S, Jones B, Villalta F, Dash C. A Novel Role of Proline Oxidase in HIV-1 Envelope Glycoprotein-induced Neuronal Autophagy. J Biol Chem. 2015 Oct 16; 290(42):25439-51.

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Costantini LM, Irvin SC, Kennedy SC, Guo F, Goldstein H, Herold BC, Snapp EL. Engineering and exploitation of a fluorescent HIV-1 gp120 for live cell CD4 binding assays. Virology. 2015 Feb; 476:240-248.

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Khayat R, Lee JH, Julien JP, Cupo A, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Structural characterization of cleaved, soluble HIV-1 envelope glycoprotein trimers. J Virol. 2013 Sep; 87(17):9865-72.

View in: PubMed

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