Dinoprostone

"Dinoprostone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The most common and most biologically active of the mammalian prostaglandins. It exhibits most biological activities characteristic of prostaglandins and has been used extensively as an oxytocic agent. The compound also displays a protective effect on the intestinal mucosa.

Descriptor ID	D015232
MeSH Number(s)	D10.251.355.255.550.250.200 D23.469.050.175.725.250.200
Concept/Terms	Dinoprostone Dinoprostone PGE2 alpha alpha, PGE2 Prostaglandin E2alpha E2alpha, Prostaglandin Prostaglandin E2 E2, Prostaglandin Prostaglandin E2 alpha E2 alpha, Prostaglandin alpha, Prostaglandin E2 PGE2 PGE2alpha Prepidil Gel Prepidil Gel Gel, Prepidil Prostenon Prostenon

Below are MeSH descriptors whose meaning is more general than "Dinoprostone".

Chemicals and Drugs [D]
Lipids [D10]
Fatty Acids [D10.251]
Fatty Acids, Unsaturated [D10.251.355]
Eicosanoids [D10.251.355.255]
Prostaglandins [D10.251.355.255.550]
Prostaglandins E [D10.251.355.255.550.250]
Dinoprostone [D10.251.355.255.550.250.200]
Biological Factors [D23]
Inflammation Mediators [D23.469]
Autacoids [D23.469.050]
Eicosanoids [D23.469.050.175]
Prostaglandins [D23.469.050.175.725]
Prostaglandins E [D23.469.050.175.725.250]
Dinoprostone [D23.469.050.175.725.250.200]

Below are MeSH descriptors whose meaning is related to "Dinoprostone".

Below are MeSH descriptors whose meaning is more specific than "Dinoprostone".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dinoprostone" by people in this website by year, and whether "Dinoprostone" was a major or minor topic of these publications.

Bar chart showing 50 publications over 21 distinct years, with a maximum of 5 publications in 2006 and 2010 and 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	1	0	1
1998	0	1	1
1999	0	1	1
2000	1	0	1
2001	1	1	2
2002	0	4	4
2003	1	1	2
2004	0	4	4
2005	1	2	3
2006	0	5	5
2007	0	2	2
2008	0	2	2
2009	1	2	3
2010	3	2	5
2012	1	4	5
2013	2	0	2
2015	0	1	1
2018	0	1	1
2022	0	3	3
2023	0	1	1

Below are the most recent publications written about "Dinoprostone" by people in Profiles.

Kotas ME, Patel NN, Cope EK, Gurrola JG, Goldberg AN, Pletcher SD, Seibold MA, Moore CM, Gordon ED. IL-13-associated epithelial remodeling correlates with clinical severity in nasal polyposis. J Allergy Clin Immunol. 2023 05; 151(5):1277-1285.

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Liu Y, Liu R, Huang L, Zuo G, Dai J, Gao L, Shi H, Fang Y, Lu Q, Okada T, Wang Z, Hu X, Lenahan C, Tang J, Xiao J, Zhang JH. Inhibition of Prostaglandin E2 Receptor EP3 Attenuates Oxidative Stress and Neuronal Apoptosis Partially by Modulating p38MAPK/FOXO3/Mul1/Mfn2 Pathway after Subarachnoid Hemorrhage in Rats. Oxid Med Cell Longev. 2022; 2022:7727616.

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Wallace CH, Oliveros G, Serrano PA, Rockwell P, Xie L, Figueiredo-Pereira M. Timapiprant, a prostaglandin D2 receptor antagonist, ameliorates pathology in a rat Alzheimer's model. Life Sci Alliance. 2022 09 27; 5(12).

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Kotas ME, Moore CM, Gurrola JG, Pletcher SD, Goldberg AN, Alvarez R, Yamato S, Bratcher PE, Shaughnessy CA, Zeitlin PL, Zhang IH, Li Y, Montgomery MT, Lee K, Cope EK, Locksley RM, Seibold MA, Gordon ED. IL-13-programmed airway tuft cells produce PGE2, which promotes CFTR-dependent mucociliary function. JCI Insight. 2022 07 08; 7(13).

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Schexnayder C, Broussard K, Onuaguluchi D, Poch? A, Ismail M, McAtee L, Llopis S, Keizerweerd A, McFerrin H, Williams C. Metformin Inhibits Migration and Invasion by Suppressing ROS Production and COX2 Expression in MDA-MB-231 Breast Cancer Cells. Int J Mol Sci. 2018 Nov 21; 19(11).

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Kim S, Campbell J, Yoo W, Taylor JA, Sandler DP. Systemic Levels of Estrogens and PGE2 Synthesis in Relation to Postmenopausal Breast Cancer Risk. Cancer Epidemiol Biomarkers Prev. 2017 03; 26(3):383-388.

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Boutaud O, Sosa IR, Amin T, Oram D, Adler D, Hwang HS, Crews BC, Milne G, Harris BK, Hoeksema M, Knollmann BC, Lammers PE, Marnett LJ, Massion PP, Oates JA. Inhibition of the Biosynthesis of Prostaglandin E2 By Low-Dose Aspirin: Implications for Adenocarcinoma Metastasis. Cancer Prev Res (Phila). 2016 Nov; 9(11):855-865.

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Awji EG, Chand H, Bruse S, Smith KR, Colby JK, Mebratu Y, Levy BD, Tesfaigzi Y. Wood smoke enhances cigarette smoke-induced inflammation by inducing the aryl hydrocarbon receptor repressor in airway epithelial cells. Am J Respir Cell Mol Biol. 2015 Mar; 52(3):377-86.

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Vo BT, Morton D, Komaragiri S, Millena AC, Leath C, Khan SA. TGF-? effects on prostate cancer cell migration and invasion are mediated by PGE2 through activation of PI3K/AKT/mTOR pathway. Endocrinology. 2013 May; 154(5):1768-79.

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Hsu WT, Lin CH, Chiang BL, Jui HY, Wu KK, Lee CM. Prostaglandin E2 potentiates mesenchymal stem cell-induced IL-10+IFN-?+CD4+ regulatory T cells to control transplant arteriosclerosis. J Immunol. 2013 Mar 01; 190(5):2372-80.

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