"Proline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.
Descriptor ID |
D011392
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MeSH Number(s) |
D12.125.072.401.623
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Proline".
Below are MeSH descriptors whose meaning is more specific than "Proline".
This graph shows the total number of publications written about "Proline" by people in this website by year, and whether "Proline" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 |
1997 | 0 | 1 | 1 |
1998 | 2 | 0 | 2 |
1999 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 1 | 1 | 2 |
2003 | 0 | 1 | 1 |
2004 | 0 | 2 | 2 |
2005 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2008 | 3 | 1 | 4 |
2009 | 0 | 2 | 2 |
2010 | 1 | 0 | 1 |
2012 | 1 | 0 | 1 |
2013 | 1 | 0 | 1 |
2014 | 1 | 0 | 1 |
2015 | 1 | 1 | 2 |
2017 | 0 | 1 | 1 |
2021 | 3 | 0 | 3 |
2022 | 0 | 2 | 2 |
2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proline" by people in Profiles.
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Chen X, Raiff A, Li S, Guo Q, Zhang J, Zhou H, Timms RT, Yao X, Elledge SJ, Koren I, Zhang K, Xu C. Mechanism of ?-Pro/C-degron recognition by the CRL2FEM1B ubiquitin ligase. Nat Commun. 2024 Apr 26; 15(1):3558.
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Wiere S, Sugai C, Espiritu MJ, Aurelio VP, Reyes CD, Yuzon N, Whittal RM, Tytgat J, Peigneur S, Bingham JP. Research into the Bioengineering of a Novel a-Conotoxin from the Milked Venom of Conus obscurus. Int J Mol Sci. 2022 Oct 11; 23(20).
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Dahiya R, Dahiya S, Chennupati SV, Davis V, Sahadeo V, Patel JK. Towards the Synthesis of a Heterocyclic Analogue of Natural Cyclooligopeptide with Improved Bio-properties. Curr Org Synth. 2022 03 03; 19(2):267-278.
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Ghosh UK, Islam MN, Siddiqui MN, Cao X, Khan MAR. Proline, a multifaceted signalling molecule in plant responses to abiotic stress: understanding the physiological mechanisms. Plant Biol (Stuttg). 2022 Mar; 24(2):227-239.
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Dash S, Dash C, Pandhare J. Activation of proline metabolism maintains ATP levels during cocaine-induced polyADP-ribosylation. Amino Acids. 2021 Dec; 53(12):1903-1915.
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Jones B, Balasubramaniam M, Lebowitz JJ, Taylor A, Villalta F, Khoshbouei H, Grueter C, Grueter B, Dash C, Pandhare J. Activation of proline biosynthesis is critical to maintain glutamate homeostasis during acute methamphetamine exposure. Sci Rep. 2021 01 14; 11(1):1422.
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Rueli RH, Torres DJ, Dewing AS, Kiyohara AC, Barayuga SM, Bellinger MT, Uyehara-Lock JH, White LR, Moreira PI, Berry MJ, Perry G, Bellinger FP. Selenoprotein S Reduces Endoplasmic Reticulum Stress-Induced Phosphorylation of Tau: Potential Role in Selenate Mitigation of Tau Pathology. J Alzheimers Dis. 2017; 55(2):749-762.
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Altiti AS, Bachan S, Alrowhani W, Mootoo DR. An organocatalytic strategy for the stereoselective synthesis of C-galactosides with fluorine at the pseudoanomeric carbon. Org Biomol Chem. 2015 Nov 07; 13(41):10328-35.
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Sanchez-Espiridion B, Liang D, Ajani JA, Liang S, Ye Y, Hildebrandt MA, Gu J, Wu X. Identification of Serum Markers of Esophageal Adenocarcinoma by Global and Targeted Metabolic Profiling. Clin Gastroenterol Hepatol. 2015 Oct; 13(10):1730-1737.e9.
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Liang S, Sanchez-Espiridion B, Xie H, Ma J, Wu X, Liang D. Determination of proline in human serum by a robust LC-MS/MS method: application to identification of human metabolites as candidate biomarkers for esophageal cancer early detection and risk stratification. Biomed Chromatogr. 2015 Apr; 29(4):570-7.