Prolactin

"Prolactin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A lactogenic hormone secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). It is a polypeptide of approximately 23 kD. Besides its major action on lactation, in some species prolactin exerts effects on reproduction, maternal behavior, fat metabolism, immunomodulation and osmoregulation. Prolactin receptors are present in the mammary gland, hypothalamus, liver, ovary, testis, and prostate.

Descriptor ID	D011388
MeSH Number(s)	D06.472.699.322.576.773 D06.472.699.631.525.525 D12.644.548.691.525.525
Concept/Terms	Prolactin Prolactin Mammotropic Hormone, Pituitary Hormone, Pituitary Mammotropic Pituitary Mammotropic Hormone PRL (Prolactin) Lactogenic Hormone, Pituitary Hormone, Pituitary Lactogenic Pituitary Lactogenic Hormone Mammotropin

Below are MeSH descriptors whose meaning is more general than "Prolactin".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Gonadotropins [D06.472.699.322]
Gonadotropins, Pituitary [D06.472.699.322.576]
Prolactin [D06.472.699.322.576.773]
Pituitary Hormones [D06.472.699.631]
Pituitary Hormones, Anterior [D06.472.699.631.525]
Prolactin [D06.472.699.631.525.525]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Peptide Hormones [D12.644.548]
Pituitary Hormones [D12.644.548.691]
Pituitary Hormones, Anterior [D12.644.548.691.525]
Prolactin [D12.644.548.691.525.525]

Below are MeSH descriptors whose meaning is related to "Prolactin".

Below are MeSH descriptors whose meaning is more specific than "Prolactin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Prolactin" by people in this website by year, and whether "Prolactin" was a major or minor topic of these publications.

Bar chart showing 33 publications over 20 distinct years, with a maximum of 4 publications in 1998

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	3	0	3
1997	2	1	3
1998	2	2	4
1999	0	1	1
2001	1	0	1
2002	1	1	2
2004	0	2	2
2005	0	1	1
2006	1	0	1
2007	2	1	3
2010	1	1	2
2012	0	1	1
2015	1	1	2
2017	0	1	1
2019	1	0	1
2020	1	0	1
2022	1	0	1
2023	0	1	1
2024	1	0	1
2026	1	0	1

Below are the most recent publications written about "Prolactin" by people in Profiles.

Breves JP, Hu MW, Inokuchi M, Seale LA, Seale AP. Prolactin, cortisol, and extracellular osmolality regulate cftr, ostf1, and sgk1 in tilapia ionocytes. Front Endocrinol (Lausanne). 2026; 17:1802254.

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Williams A, Hossack DJ, Thompson N, Sim YE, Wilson C, Schuch V, Hailstorks T, Chakraborty R, Johnson EL. Elevated levels of exogenous prolactin promote inflammation at the maternal-fetal interface via the JAK2/STAT5B signaling axis. Front Immunol. 2024; 15:1496610.

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Nayyar S, Archibong A, Nayyar T. Testosterone and Prolactin Perturbations Possibly Associated with Reduced Levels of ?-Arrestin1 in Mononuclear Leukocytes of Women with Premenstrual Dysphoric Disorder. Int J Mol Sci. 2023 Oct 22; 24(20).

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Malintha GHT, Celino-Brady FT, Stoytcheva ZR, Seale AP. Osmosensitive transcription factors in the prolactin cell of a euryhaline teleost. Comp Biochem Physiol A Mol Integr Physiol. 2023 04; 278:111356.

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Seale AP, Malintha GHT, Celino-Brady FT, Head T, Belcaid M, Yamaguchi Y, Lerner DT, Baltzegar DA, Borski RJ, Stoytcheva ZR, Breves JP. Transcriptional regulation of prolactin in a euryhaline teleost: Characterisation of gene promoters through in silico and transcriptome analyses. J Neuroendocrinol. 2020 11; 32(11):e12905.

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Leung YT, Maurer K, Song L, Convissar J, Sullivan KE. Prolactin activates IRF1 and leads to altered balance of histone acetylation: Implications for systemic lupus erythematosus. Mod Rheumatol. 2020 May; 30(3):532-543.

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H?sing A, Fortner RT, K?hn T, Overvad K, Tj?nneland A, Olsen A, Boutron-Ruault MC, Severi G, Fournier A, Boeing H, Trichopoulou A, Benetou V, Orfanos P, Masala G, Pala V, Tumino R, Fasanelli F, Panico S, Bueno de Mesquita HB, Peeters PH, van Gills CH, Quir?s JR, Agudo A, S?nchez MJ, Chirlaque MD, Barricarte A, Amiano P, Khaw KT, Travis RC, Dossus L, Li K, Ferrari P, Merritt MA, Tzoulaki I, Riboli E, Kaaks R. Added Value of Serum Hormone Measurements in Risk Prediction Models for Breast Cancer for Women Not Using Exogenous Hormones: Results from the EPIC Cohort. Clin Cancer Res. 2017 Aug 01; 23(15):4181-4189.

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Yu PL, Cheng SY, Chou JC, Pan WH, Wang SW, Wang PS. Regulation of Intermittent Hypoxia on Brain Dopamine in Amphetaminized Rats. Chin J Physiol. 2015 Aug 31; 58(4):219-27.

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Tikk K, Sookthai D, Fortner RT, Johnson T, Rinaldi S, Romieu I, Tj?nneland A, Olsen A, Overvad K, Clavel-Chapelon F, Baglietto L, Boeing H, Trichopoulou A, Lagiou P, Trichopoulos D, Masala G, Krogh V, Tumino R, Ricceri F, Mattiello A, Agudo A, Men?ndez V, S?nchez MJ, Amiano P, Chirlaque MD, Barricarte A, Bueno-de-Mesquita HB, Monninkhof EM, Onland-Moret NC, Andresson A, Sund M, Weiderpass E, Khaw KT, Key TJ, Travis RC, Merritt MA, Riboli E, Dossus L, Kaaks R. Circulating prolactin and in situ breast cancer risk in the European EPIC cohort: a case-control study. Breast Cancer Res. 2015 Mar 31; 17:49.

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Fleming JM, Ginsburg E, McAndrew CW, Heger CD, Cheston L, Rodriguez-Canales J, Vonderhaar BK, Goldsmith P. Characterization of ?7/11, a functional prolactin-binding protein. J Mol Endocrinol. 2013 Feb; 50(1):79-90.

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