"Nicardipine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
| Descriptor ID |
D009529
|
| MeSH Number(s) |
D03.383.725.203.510
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nicardipine".
Below are MeSH descriptors whose meaning is more specific than "Nicardipine".
This graph shows the total number of publications written about "Nicardipine" by people in this website by year, and whether "Nicardipine" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nicardipine" by people in Profiles.
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Li X, Chen Y, Bai L, Zhao R, Wu Y, Xie ZR, Wu JM, Bowen NJ, Danaher A, Cook N, Li D, Qui M, Du Y, Fu H, Osunkoya AO, Kucuk O, Wu D. Nicardipine is a putative EED inhibitor and has high selectivity and potency against chemoresistant prostate cancer in preclinical models. Br J Cancer. 2023 09; 129(5):884-894.
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Zhang P, Weeranoppanant N, Thomas DA, Tahara K, Stelzer T, Russell MG, O'Mahony M, Myerson AS, Lin H, Kelly LP, Jensen KF, Jamison TF, Dai C, Cui Y, Briggs N, Beingessner RL, Adamo A. Advanced Continuous Flow Platform for On-Demand Pharmaceutical Manufacturing. Chemistry. 2018 Feb 21; 24(11):2776-2784.
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Rothnie A, Storm J, McMahon R, Taylor A, Kerr ID, Callaghan R. The coupling mechanism of P-glycoprotein involves residue L339 in the sixth membrane spanning segment. FEBS Lett. 2005 Jul 18; 579(18):3984-90.
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Zubkov AY, Rollins KS, Zhang JH. KCl activates mitogen-activated protein kinase in rabbit bailar artery. Biochem Biophys Res Commun. 2002 Apr 26; 293(1):660-4.
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Calhoun DA, Wei CC, Zhu S, Bradley WE, Dell'Italia LJ. Enalaprilat blunts reflexive increases in cardiac interstitial norepinephrine in conscious rats. J Hypertens. 2001 Nov; 19(11):2025-9.
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Calhoun DA, Zhu S. Pretreatment with enalaprilat blunts nicardipine-induced sympathetic activation in spontaneously hypertensive and Wistar-Kyoto rats. J Hypertens. 1999 Apr; 17(4):507-12.
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Willis AL, Nagel B, Churchill V, Whyte MA, Smith DL, Mahmud I, Puppione DL. Antiatherosclerotic effects of nicardipine and nifedipine in cholesterol-fed rabbits. Arteriosclerosis. 1985 May-Jun; 5(3):250-5.