"Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of enzymes of the transferase class that catalyze the transfer of a methyl group from one compound to another. (Dorland, 28th ed) EC 2.1.1.
| Descriptor ID |
D008780
|
| MeSH Number(s) |
D08.811.913.555.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Methyltransferases".
This graph shows the total number of publications written about "Methyltransferases" by people in this website by year, and whether "Methyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 4 | 2 | 6 |
| 2013 | 2 | 1 | 3 |
| 2014 | 4 | 2 | 6 |
| 2015 | 5 | 0 | 5 |
| 2016 | 3 | 1 | 4 |
| 2017 | 5 | 1 | 6 |
| 2018 | 1 | 1 | 2 |
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Below are the most recent publications written about "Methyltransferases" by people in Profiles.
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Zhou W, Debnath A, Jennings G, Hahn HJ, Vanderloop BH, Chaudhuri M, Nes WD, Podust LM. Enzymatic chokepoints and synergistic drug targets in the sterol biosynthesis pathway of Naegleria fowleri. PLoS Pathog. 2018 09; 14(9):e1007245.
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Packianathan C, Kandavelu P, Rosen BP. The Structure of an As(III) S-Adenosylmethionine Methyltransferase with 3-Coordinately Bound As(III) Depicts the First Step in Catalysis. Biochemistry. 2018 07 17; 57(28):4083-4092.
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Huang K, Xu Y, Packianathan C, Gao F, Chen C, Zhang J, Shen Q, Rosen BP, Zhao FJ. Arsenic methylation by a novel ArsM As(III) S-adenosylmethionine methyltransferase that requires only two conserved cysteine residues. Mol Microbiol. 2018 01; 107(2):265-276.
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Kidane ME, Vanderloop BH, Zhou W, Thomas CD, Ramos E, Singha U, Chaudhuri M, Nes WD. Sterol methyltransferase a target for anti-amoeba therapy: towards transition state analog and suicide substrate drug design. J Lipid Res. 2017 12; 58(12):2310-2323.
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Chen SC, Sun GX, Rosen BP, Zhang SY, Deng Y, Zhu BK, Rensing C, Zhu YG. Recurrent horizontal transfer of arsenite methyltransferase genes facilitated adaptation of life to arsenic. Sci Rep. 2017 08 10; 7(1):7741.
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Li J, Packianathan C, Rossman TG, Rosen BP. Nonsynonymous Polymorphisms in the Human AS3MT Arsenic Methylation Gene: Implications for Arsenic Toxicity. Chem Res Toxicol. 2017 07 17; 30(7):1481-1491.
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Aubee JI, Olu M, Thompson KM. TrmL and TusA Are Necessary for rpoS and MiaA Is Required for hfq Expression in Escherichia coli. Biomolecules. 2017 05 04; 7(2).
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Chen J, Li J, Jiang X, Rosen BP. Conserved cysteine residues determine substrate specificity in a novel As(III) S-adenosylmethionine methyltransferase from Aspergillus fumigatus. Mol Microbiol. 2017 04; 104(2):250-259.
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Miller MB, Patkar P, Singha UK, Chaudhuri M, David Nes W. 24-Methylenecyclopropane steroidal inhibitors: A Trojan horse in ergosterol biosynthesis that prevents growth of Trypanosoma brucei. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Mar; 1862(3):305-313.
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Li J, Pawitwar SS, Rosen BP. The organoarsenical biocycle and the primordial antibiotic methylarsenite. Metallomics. 2016 10 01; 8(10):1047-1055.