Lipopolysaccharides

"Lipopolysaccharides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Lipid-containing polysaccharides which are endotoxins and important group-specific antigens. They are often derived from the cell wall of gram-negative bacteria and induce immunoglobulin secretion. The lipopolysaccharide molecule consists of three parts: LIPID A, core polysaccharide, and O-specific chains (O ANTIGENS). When derived from Escherichia coli, lipopolysaccharides serve as polyclonal B-cell mitogens commonly used in laboratory immunology. (From Dorland, 28th ed)

Descriptor ID	D008070
MeSH Number(s)	D09.400.500 D09.698.718.450 D10.494 D23.050.161.616.525 D23.946.123.329.500
Concept/Terms	Lipopolysaccharides Lipopolysaccharides Lipoglycans

Below are MeSH descriptors whose meaning is more general than "Lipopolysaccharides".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycoconjugates [D09.400]
Lipopolysaccharides [D09.400.500]
Polysaccharides [D09.698]
Polysaccharides, Bacterial [D09.698.718]
Lipopolysaccharides [D09.698.718.450]
Lipids [D10]
Lipopolysaccharides [D10.494]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Bacterial [D23.050.161]
Polysaccharides, Bacterial [D23.050.161.616]
Lipopolysaccharides [D23.050.161.616.525]
Toxins, Biological [D23.946]
Bacterial Toxins [D23.946.123]
Endotoxins [D23.946.123.329]
Lipopolysaccharides [D23.946.123.329.500]

Below are MeSH descriptors whose meaning is related to "Lipopolysaccharides".

Below are MeSH descriptors whose meaning is more specific than "Lipopolysaccharides".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Lipopolysaccharides" by people in this website by year, and whether "Lipopolysaccharides" was a major or minor topic of these publications.

Bar chart showing 171 publications over 28 distinct years, with a maximum of 15 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	2	2
1999	0	1	1
2000	0	3	3
2001	4	1	5
2002	4	7	11
2003	2	5	7
2004	4	11	15
2005	3	2	5
2006	3	3	6
2007	6	3	9
2008	2	3	5
2009	2	6	8
2010	2	5	7
2011	6	2	8
2012	1	4	5
2013	2	6	8
2014	2	2	4
2015	1	5	6
2016	1	10	11
2017	1	4	5
2018	4	4	8
2019	2	3	5
2020	2	4	6
2021	2	2	4
2022	0	3	3
2023	0	6	6
2024	2	3	5
2025	0	3	3

Below are the most recent publications written about "Lipopolysaccharides" by people in Profiles.

Armina-Rodriguez A, Vald?s Fernandez BN, Ocasio-Malav? C, Cantres Rosario YM, Carrasquillo Carri?n K, Mel?ndez LM, Roche Lima A, Tosado Rodriguez EL, Espino AM. Quantitative Proteomics Reveals Fh15 as an Antagonist of TLR4 Downregulating the Activation of NF-?B, Inducible Nitric Oxide, Phagosome Signaling Pathways, and Oxidative Stress of LPS-Stimulated Macrophages. Int J Mol Sci. 2025 Jul 18; 26(14).

View in: PubMed
Lee HJ, Lee NK, Kim J, Kim J, Seo D, Shin HE, Kim J, Ahn JH, Kim SN, Kim HS, Park J, Park W, Hong KS, Park CG, Lee W. Sequential nanoparticle therapy targeting neutrophil hyperactivation to prevent neutrophil-induced pulmonary fibrosis. J Nanobiotechnology. 2025 May 26; 23(1):381.

View in: PubMed
Rorex C, Cardona SM, Church KA, Rodriguez D, Vanegas D, Saldivar RA, El-Sheikh A, Wang Y, Gyoneva S, Cotleur AC, Cardona AE. CX3CR1-Fractalkine Dysregulation Affects Retinal GFAP Expression, Inflammatory Gene Induction, and LPS Response in a Mouse Model of Hypoxic Retinopathy. Int J Mol Sci. 2025 Jan 28; 26(3).

View in: PubMed
Warner S, Teague HL, Ramos-Benitez MJ, Panicker S, Allen K, Gairhe S, Moyer T, Parachalil Gopalan B, Douagi I, Shet A, Kanthi Y, Suffredini AF, Chertow DS, Strich JR. R406 reduces lipopolysaccharide-induced neutrophil activation. Cell Immunol. 2024 Sep-Oct; 403-404:104860.

View in: PubMed
Ma C, Hoffmann FW, Shay AE, Koo I, Green KA, Green WR, Hoffmann PR. Upregulated selenoprotein I during lipopolysaccharide-induced B cell activation promotes lipidomic changes and is required for effective differentiation into IgM-secreting plasma B cells. J Leukoc Biol. 2024 06 28; 116(1):6-17.

View in: PubMed
Sampath C, Chukkapalli SS, Raju AV, Alluri LSC, Srisai D, Gangula PR. Cinnamaldehyde Protects against P. gingivalis Induced Intestinal Epithelial Barrier Dysfunction in IEC-6 Cells via the PI3K/Akt-Mediated NO/Nrf2 Signaling Pathway. Int J Mol Sci. 2024 Apr 26; 25(9).

View in: PubMed
Shipman JG, Onyenwoke RU, Sivaraman V. Vaping-Dependent Pulmonary Inflammation Is Ca2+ Mediated and Potentially Sex Specific. Int J Mol Sci. 2024 Feb 01; 25(3).

View in: PubMed
Long CM, Beare PA, Cockrell D, Binette P, Tesfamariam M, Richards C, Anderson M, McCormick-Ell J, Brose M, Anderson R, Omsland A, Pearson T, Heinzen RA. Natural reversion promotes LPS elongation in an attenuated Coxiella burnetii strain. Nat Commun. 2024 Jan 24; 15(1):697.

View in: PubMed
Valdes-Fernandez BN, Ruiz-Jimenez C, Armina-Rodriguez A, Mendez LB, Espino AM. Fasciola hepatica GST mu-class suppresses the cytokine storm induced by E. coli-lipopolysaccharide, whereas it modulates the dynamic of peritoneal macrophages in a mouse model and suppresses the classical activation of macrophages. Microbiol Spectr. 2024 Jan 11; 12(1):e0347523.

View in: PubMed
Chang L, Zhang A, Liu W, Cao P, Dong L, Gao X. Calycosin inhibits hepatocyte apoptosis in acute liver failure by suppressing the TLR4/NF-?B pathway: An in vitro study. Immun Inflamm Dis. 2023 07; 11(7):e935.

View in: PubMed

People

Explore

Similar Concepts

Top Journals