"Ketoconazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.
| Descriptor ID |
D007654
|
| MeSH Number(s) |
D03.383.606.560
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ketoconazole".
Below are MeSH descriptors whose meaning is more specific than "Ketoconazole".
This graph shows the total number of publications written about "Ketoconazole" by people in this website by year, and whether "Ketoconazole" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ketoconazole" by people in Profiles.
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Hargrove TY, Garvey EP, Hoekstra WJ, Yates CM, Wawrzak Z, Rachakonda G, Villalta F, Lepesheva GI. Crystal Structure of the New Investigational Drug Candidate VT-1598 in Complex with Aspergillus fumigatus Sterol 14a-Demethylase Provides Insights into Its Broad-Spectrum Antifungal Activity. Antimicrob Agents Chemother. 2017 07; 61(7).
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Robles-Escajeda E, Mart?nez A, Varela-Ramirez A, S?nchez-Delgado RA, Aguilera RJ. Analysis of the cytotoxic effects of ruthenium-ketoconazole and ruthenium-clotrimazole complexes on cancer cells. Cell Biol Toxicol. 2013 Dec; 29(6):431-43.
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Iniguez E, S?nchez A, Vasquez MA, Mart?nez A, Olivas J, Sattler A, S?nchez-Delgado RA, Maldonado RA. Metal-drug synergy: new ruthenium(II) complexes of ketoconazole are highly active against Leishmania major and Trypanosoma cruzi and nontoxic to human or murine normal cells. J Biol Inorg Chem. 2013 Oct; 18(7):779-90.
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Karla PK, Pal D, Mitra AK. Molecular evidence and functional expression of multidrug resistance associated protein (MRP) in rabbit corneal epithelial cells. Exp Eye Res. 2007 Jan; 84(1):53-60.
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Kang SK, Jee MS, Choi JH, Sung KJ, Moon KC, Koh JK. A case of infantile acne due to pityrosporum. Pediatr Dermatol. 2003 Jan-Feb; 20(1):68-70.
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Maldonado RA, Molina J, Payares G, Urbina JA. Experimental chemotherapy with combinations of ergosterol biosynthesis inhibitors in murine models of Chagas' disease. Antimicrob Agents Chemother. 1993 Jun; 37(6):1353-9.
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Urbina JA, Lazardi K, Marchan E, Visbal G, Aguirre T, Piras MM, Piras R, Maldonado RA, Payares G, de Souza W. Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies. Antimicrob Agents Chemother. 1993 Mar; 37(3):580-91.