"Keratins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of fibrous proteins or scleroproteins that represents the principal constituent of EPIDERMIS; HAIR; NAILS; horny tissues, and the organic matrix of tooth ENAMEL. Two major conformational groups have been characterized, alpha-keratin, whose peptide backbone forms a coiled-coil alpha helical structure consisting of TYPE I KERATIN and a TYPE II KERATIN, and beta-keratin, whose backbone forms a zigzag or pleated sheet structure. alpha-Keratins have been classified into at least 20 subtypes. In addition multiple isoforms of subtypes have been found which may be due to GENE DUPLICATION.
Descriptor ID |
D007633
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MeSH Number(s) |
D05.750.078.593.450 D12.776.220.475.450 D12.776.860.607
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Keratins".
Below are MeSH descriptors whose meaning is more specific than "Keratins".
This graph shows the total number of publications written about "Keratins" by people in this website by year, and whether "Keratins" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2002 | 0 | 1 | 1 |
2004 | 1 | 1 | 2 |
2005 | 2 | 1 | 3 |
2006 | 0 | 2 | 2 |
2009 | 0 | 2 | 2 |
2010 | 0 | 1 | 1 |
2015 | 0 | 1 | 1 |
2018 | 1 | 1 | 2 |
2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Keratins" by people in Profiles.
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Mehta A, Azam S, Rahmani A, Rizvi M, Mandal A. Expression of epithelial membrane antigen and cytokeratin among Indian workers exposed to cotton fibre dust in textile industries. East Mediterr Health J. 2022 Feb 27; 28(2):152-157.
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Lim J, Ramesh A, Shioda T, Leon Parada K, Luderer U. Sex Differences in Embryonic Gonad Transcriptomes and Benzo[a]pyrene Metabolite Levels After Transplacental Exposure. Endocrinology. 2022 01 01; 163(1).
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Coghill AE, Bellizzi AM, Lynch CF, Shiels MS, Selk FR, Gillison M, Hernandez BY, Chan OTM, Engels EA. Pathology Characterization and Detection of Human Papillomavirus Type 16 in Rectal Squamous Cell Carcinomas. Clin Gastroenterol Hepatol. 2019 09; 17(10):2129-2131.
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Kok MK, Chambers JK, Ong SM, Nakayama H, Uchida K. Hierarchical Cluster Analysis of Cytokeratins and Stem Cell Expression Profiles of Canine Cutaneous Epithelial Tumors. Vet Pathol. 2018 11; 55(6):821-837.
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Singh SP, Chand HS, Gundavarapu S, Saeed AI, Langley RJ, Tesfaigzi Y, Mishra NC, Sopori ML. HIF-1a Plays a Critical Role in the Gestational Sidestream Smoke-Induced Bronchopulmonary Dysplasia in Mice. PLoS One. 2015; 10(9):e0137757.
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Osada M, Jardine L, Misir R, Andl T, Millar SE, Pezzano M. DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration. PLoS One. 2010 Feb 08; 5(2):e9062.
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Hendrix TM, Chilukuri RV, Martinez M, Olushoga Z, Blake A, Brohi M, Walker C, Samms M, Guyden JC. Thymic nurse cells exhibit epithelial progenitor phenotype and create unique extra-cytoplasmic membrane space for thymocyte selection. Cell Immunol. 2010; 261(2):81-92.
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Alimova A, Chakraverty R, Muthukattil R, Elder S, Katz A, Sriramoju V, Lipper S, Alfano RR. In vivo molecular evaluation of guinea pig skin incisions healing after surgical suture and laser tissue welding using Raman spectroscopy. J Photochem Photobiol B. 2009 Sep 04; 96(3):178-83.
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Gupta R, Singh S, Hedau S, Nigam S, Das BC, Singh I, Mandal AK. Spindle cell carcinoma of head and neck: an immunohistochemical and molecular approach to its pathogenesis. J Clin Pathol. 2007 May; 60(5):472-5.
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Liu BC, Zhang JD, Zhang XL, Wu GQ, Li MX. Role of connective tissue growth factor (CTGF) module 4 in regulating epithelial mesenchymal transition (EMT) in HK-2 cells. Clin Chim Acta. 2006 Nov; 373(1-2):144-50.