"Fucosyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes catalyzing the transfer of fucose from a nucleoside diphosphate fucose to an acceptor molecule which is frequently another carbohydrate, a glycoprotein, or a glycolipid molecule. Elevated activity of some fucosyltransferases in human serum may serve as an indicator of malignancy. The class includes EC 2.4.1.65; EC 2.4.1.68; EC 2.4.1.69; EC 2.4.1.89.
| Descriptor ID |
D005647
|
| MeSH Number(s) |
D08.811.913.400.450.300
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Fucosyltransferases".
Below are MeSH descriptors whose meaning is more specific than "Fucosyltransferases".
This graph shows the total number of publications written about "Fucosyltransferases" by people in this website by year, and whether "Fucosyltransferases" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Fucosyltransferases" by people in Profiles.
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Montesino B, Steenackers A, Lozano JM, Young GD, Hu N, Sackstein R, Chandler KB. Identification of a1,2-fucosylated signaling and adhesion molecules in head and neck squamous cell carcinoma. Glycobiology. 2022 04 21; 32(5):441-455.
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Polfus LM, Raffield LM, Wheeler MM, Tracy RP, Lange LA, Lettre G, Miller A, Correa A, Bowler RP, Bis JC, Salimi S, Jenny NS, Pankratz N, Wang B, Preuss MH, Zhou L, Moscati A, Nadkarni GN, Loos RJF, Zhong X, Li B, Johnsen JM, Nickerson DA, Reiner AP, Auer PL. Whole genome sequence association with E-selectin levels reveals loss-of-function variant in African Americans. Hum Mol Genet. 2019 02 01; 28(3):515-523.
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Katkoori VR, Shanmugam C, Jia X, Vitta SP, Sthanam M, Callens T, Messiaen L, Chen D, Zhang B, Bumpers HL, Samuel T, Manne U. Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable stage III colorectal adenocarcinomas. PLoS One. 2012; 7(1):e30020.
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Ma B, Simala-Grant JL, Taylor DE. Fucosylation in prokaryotes and eukaryotes. Glycobiology. 2006 Dec; 16(12):158R-184R.
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Ma B, Audette GF, Lin S, Palcic MM, Hazes B, Taylor DE. Purification, kinetic characterization, and mapping of the minimal catalytic domain and the key polar groups of Helicobacter pylori alpha-(1,3/1,4)-fucosyltransferases. J Biol Chem. 2006 Mar 10; 281(10):6385-94.
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Ma B, Lau LH, Palcic MM, Hazes B, Taylor DE. A single aromatic amino acid at the carboxyl terminus of Helicobacter pylori {alpha}1,3/4 fucosyltransferase determines substrate specificity. J Biol Chem. 2005 Nov 04; 280(44):36848-56.
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Ma B, Wang G, Palcic MM, Hazes B, Taylor DE. C-terminal amino acids of Helicobacter pylori alpha1,3/4 fucosyltransferases determine type I and type II transfer. J Biol Chem. 2003 Jun 13; 278(24):21893-900.
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Wang G, Boulton PG, Chan NWC, Palcic MM, Taylor DE. Novel Helicobacter pylori alpha1,2-fucosyltransferase, a key enzyme in the synthesis of Lewis antigens. Microbiology (Reading). 1999 Nov; 145 ( Pt 11):3245-3253.