"Freund's Adjuvant" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antigen solution emulsified in mineral oil. The complete form is made up of killed, dried mycobacteria, usually M. tuberculosis, suspended in the oil phase. It is effective in stimulating cell-mediated immunity (IMMUNITY, CELLULAR) and potentiates the production of certain IMMUNOGLOBULINS in some animals. The incomplete form does not contain mycobacteria.
| Descriptor ID |
D005620
|
| MeSH Number(s) |
D20.475
|
| Concept/Terms |
Freund's Adjuvant- Freund's Adjuvant
- Adjuvant, Freund's
- Freunds Adjuvant
- Freund Adjuvant
- Adjuvant, Freund
|
Below are MeSH descriptors whose meaning is more general than "Freund's Adjuvant".
Below are MeSH descriptors whose meaning is more specific than "Freund's Adjuvant".
This graph shows the total number of publications written about "Freund's Adjuvant" by people in this website by year, and whether "Freund's Adjuvant" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Freund's Adjuvant" by people in Profiles.
-
Chase Huizar C, Ji N, Reddick R, Ostroff GR, Forsthuber TG. Glucan particles as a novel adjuvant for the induction of experimental autoimmune encephalomyelitis. Cell Immunol. 2021 08; 366:104383.
-
Sosa RA, Murphey C, Ji N, Cardona AE, Forsthuber TG. The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis. J Immunol. 2013 Dec 15; 191(12):5848-57.
-
Romero-Reyes M, Akerman S, Nguyen E, Vijjeswarapu A, Hom B, Dong HW, Charles AC. Spontaneous behavioral responses in the orofacial region: a model of trigeminal pain in mouse. Headache. 2013 Jan; 53(1):137-151.
-
Hofstetter HH, Forsthuber TG. Kinetics of IL-17- and interferon-gamma-producing PLPp-specific CD4 T cells in EAE induced by coinjection of PLPp/IFA with pertussis toxin in SJL mice. Neurosci Lett. 2010 Jun 07; 476(3):150-5.
-
Ambalavanar R, Dessem D, Moutanni A, Yallampalli C, Yallampalli U, Gangula P, Bai G. Muscle inflammation induces a rapid increase in calcitonin gene-related peptide (CGRP) mRNA that temporally relates to CGRP immunoreactivity and nociceptive behavior. Neuroscience. 2006 Dec; 143(3):875-84.
-
Denkinger M, Shive CL, Pantenburg B, Forsthuber TG. Suramin has adjuvant properties and promotes expansion of antigen-specific Th1 and Th2 cells in vivo. Int Immunopharmacol. 2004 Jan; 4(1):15-24.
-
Hofstetter HH, Sewell DL, Liu F, Sandor M, Forsthuber T, Lehmann PV, Fabry Z. Autoreactive T cells promote post-traumatic healing in the central nervous system. J Neuroimmunol. 2003 Jan; 134(1-2):25-34.
-
Hofstetter HH, Shive CL, Forsthuber TG. Pertussis toxin modulates the immune response to neuroantigens injected in incomplete Freund's adjuvant: induction of Th1 cells and experimental autoimmune encephalomyelitis in the presence of high frequencies of Th2 cells. J Immunol. 2002 Jul 01; 169(1):117-25.
-
Ebhardt MB, Shive CL, Guardia R, Gapin L, Boehm BO, Forsthuber TG. Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals. Cell Immunol. 2002 Jan; 215(1):87-97.
-
Heeger PS, Forsthuber T, Shive C, Biekert E, Genain C, Hofstetter HH, Karulin A, Lehmann PV. Revisiting tolerance induced by autoantigen in incomplete Freund's adjuvant. J Immunol. 2000 Jun 01; 164(11):5771-81.