"Ergosterol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A steroid occurring in FUNGI. Irradiation with ULTRAVIOLET RAYS results in formation of ERGOCALCIFEROL (vitamin D2).
| Descriptor ID |
D004875
|
| MeSH Number(s) |
D04.210.500.247.222.537
|
| Concept/Terms |
Ergosterol- Ergosterol
- Pro-Vitamin D2
- D2, Pro-Vitamin
- Pro Vitamin D2
- Provitamin D 2
|
Below are MeSH descriptors whose meaning is more general than "Ergosterol".
Below are MeSH descriptors whose meaning is more specific than "Ergosterol".
This graph shows the total number of publications written about "Ergosterol" by people in this website by year, and whether "Ergosterol" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ergosterol" by people in Profiles.
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Nes WD, Chaudhuri M, Leaver DJ. Druggable Sterol Metabolizing Enzymes in Infectious Diseases: Cell Targets to Therapeutic Leads. Biomolecules. 2024 Feb 20; 14(3).
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Chaudhuri M, Singha UK, Vanderloop BH, Tripathi A, Nes WD. Steroidal Antimetabolites Protect Mice against Trypanosoma brucei. Molecules. 2022 Jun 25; 27(13).
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Ling T, Lang WH, Martinez-Montemayor MM, Rivas F. Development of ergosterol peroxide probes for cellular localisation studies. Org Biomol Chem. 2019 05 29; 17(21):5223-5229.
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Li QQ, Tsai HF, Mandal A, Walker BA, Noble JA, Fukuda Y, Bennett JE. Sterol uptake and sterol biosynthesis act coordinately to mediate antifungal resistance in Candida?glabrata under azole and hypoxic stress. Mol Med Rep. 2018 05; 17(5):6585-6597.
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Sharma AI, Olson CL, Mamede JI, Gazos-Lopes F, Epting CL, Almeida IC, Engman DM. Sterol targeting drugs reveal life cycle stage-specific differences in trypanosome lipid rafts. Sci Rep. 2017 08 22; 7(1):9105.
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Miller MB, Patkar P, Singha UK, Chaudhuri M, David Nes W. 24-Methylenecyclopropane steroidal inhibitors: A Trojan horse in ergosterol biosynthesis that prevents growth of Trypanosoma brucei. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Mar; 1862(3):305-313.
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Leaver DJ, Patkar P, Singha UK, Miller MB, Haubrich BA, Chaudhuri M, Nes WD. Fluorinated Sterols Are Suicide Inhibitors of Ergosterol Biosynthesis and Growth in Trypanosoma brucei. Chem Biol. 2015 Oct 22; 22(10):1374-83.
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Haubrich BA, Singha UK, Miller MB, Nes CR, Anyatonwu H, Lecordier L, Patkar P, Leaver DJ, Villalta F, Vanhollebeke B, Chaudhuri M, Nes WD. Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growth. J Lipid Res. 2015 Feb; 56(2):331-41.
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Ichikawa H, Takada Y, Shishodia S, Jayaprakasam B, Nair MG, Aggarwal BB. Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-kappaB (NF-kappaB) activation and NF-kappaB-regulated gene expression. Mol Cancer Ther. 2006 Jun; 5(6):1434-45.
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Harding WW, Jacobs H, Lewis PA, McLean S, Reynolds WF. Cycloartanes, protolimonoids, a pregnane and a new ergostane from Trichilia reticulata. Nat Prod Lett. 2001; 15(4):253-60.