Dynorphins

"Dynorphins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of opioid peptides including dynorphin A, dynorphin B, and smaller fragments of these peptides. Dynorphins prefer kappa-opioid receptors (RECEPTORS, OPIOID, KAPPA) and have been shown to play a role as central nervous system transmitters.

Descriptor ID	D004399
MeSH Number(s)	D12.644.400.575.180 D12.776.631.650.575.180
Concept/Terms	Dynorphins Dynorphins Dynorphin Dynorphin (1-17) Dynorphin (1-17) Dynorphin A (1-17) Dynorphin A

Below are MeSH descriptors whose meaning is more general than "Dynorphins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Neuropeptides [D12.644.400]
Opioid Peptides [D12.644.400.575]
Dynorphins [D12.644.400.575.180]
Proteins [D12.776]
Nerve Tissue Proteins [D12.776.631]
Neuropeptides [D12.776.631.650]
Opioid Peptides [D12.776.631.650.575]
Dynorphins [D12.776.631.650.575.180]

Below are MeSH descriptors whose meaning is related to "Dynorphins".

Below are MeSH descriptors whose meaning is more specific than "Dynorphins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Dynorphins" by people in this website by year, and whether "Dynorphins" was a major or minor topic of these publications.

Bar chart showing 11 publications over 9 distinct years, with a maximum of 2 publications in 2008 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
2002	1	0	1
2003	1	0	1
2008	1	1	2
2009	1	0	1
2010	0	1	1
2011	1	0	1
2022	1	0	1
2024	1	1	2

Below are the most recent publications written about "Dynorphins" by people in Profiles.

Dong C, Gowrishankar R, Jin Y, He XJ, Gupta A, Wang H, Sayar-Atasoy N, Flores RJ, Mahe K, Tjahjono N, Liang R, Marley A, Or Mizuno G, Lo DK, Sun Q, Whistler JL, Li B, Gomes I, Von Zastrow M, Tejeda HA, Atasoy D, Devi LA, Bruchas MR, Banghart MR, Tian L. Unlocking opioid neuropeptide dynamics with genetically encoded biosensors. Nat Neurosci. 2024 Sep; 27(9):1844-1857.

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Wang H, Flores RJ, Yarur HE, Limoges A, Bravo-Rivera H, Casello SM, Loomba N, Enriquez-Traba J, Arenivar M, Wang Q, Ganley R, Ramakrishnan C, Fenno LE, Kim Y, Deisseroth K, Or G, Dong C, Hoon MA, Tian L, Tejeda HA. Prefrontal cortical dynorphin peptidergic transmission constrains threat-driven behavioral and network states. Neuron. 2024 Jun 19; 112(12):2062-2078.e7.

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Tejeda HA, Wang H, Flores RJ, Yarur HE. Dynorphin/Kappa-Opioid Receptor System Modulation of Cortical Circuitry. Handb Exp Pharmacol. 2022; 271:223-253.

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Nguyen K, Tseng A, Marquez P, Hamid A, Lutfy K. The role of endogenous dynorphin in ethanol-induced state-dependent CPP. Behav Brain Res. 2012 Feb 01; 227(1):58-63.

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Parikh D, Hamid A, Friedman TC, Nguyen K, Tseng A, Marquez P, Lutfy K. Stress-induced analgesia and endogenous opioid peptides: the importance of stress duration. Eur J Pharmacol. 2011 Jan 15; 650(2-3):563-7.

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Zhan S, Zhao H, J White A, Minami M, Pignataro G, Yang T, Zhu X, Lan J, Xiong Z, Steiner DF, Simon RP, Zhou A. Defective neuropeptide processing and ischemic brain injury: a study on proprotein convertase 2 and its substrate neuropeptide in ischemic brains. J Cereb Blood Flow Metab. 2009 Apr; 29(4):698-706.

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Torres-Reveron A, Khalid S, Williams TJ, Waters EM, Jacome L, Luine VN, Drake CT, McEwen BS, Milner TA. Hippocampal dynorphin immunoreactivity increases in response to gonadal steroids and is positioned for direct modulation by ovarian steroid receptors. Neuroscience. 2009 Mar 03; 159(1):204-16.

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Roma PG, Rinker JA, Serafine KM, Chen SA, Barr CS, Cheng K, Rice KC, Riley AL. Genetic and early environmental contributions to alcohol's aversive and physiological effects. Pharmacol Biochem Behav. 2008 Nov; 91(1):134-9.

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Jenab S, Festa ED, Russo SJ, Wu HB, Inturrisi CE, Quinones-Jenab V. MK-801 attenuates cocaine induction of c-fos and preprodynorphin mRNA levels in Fischer rats. Brain Res Mol Brain Res. 2003 Oct 07; 117(2):237-9.

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Jenab S, Niyomchai T, Chin J, Festa ED, Russo SJ, Perrotti LI, Quinones-Jenab V. Effects of cocaine on c-fos and preprodynorphin mRNA levels in intact and ovariectomized Fischer rats. Brain Res Bull. 2002 Jul; 58(3):295-9.

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