Adipose Tissue, Brown

"Adipose Tissue, Brown" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A thermogenic form of adipose tissue composed of BROWN ADIPOCYTES. It is found in newborns of many species including humans, and in hibernating mammals. Brown fat is richly vascularized, innervated, and densely packed with MITOCHONDRIA which can generate heat directly from the stored lipids.

Descriptor ID	D002001
MeSH Number(s)	A10.165.114.322
Concept/Terms	Adipose Tissue, Brown Adipose Tissue, Brown Tissue, Brown Adipose Brown Adipose Tissue Brown Fat Fat, Brown Hibernating Gland Hibernating Gland

Below are MeSH descriptors whose meaning is more general than "Adipose Tissue, Brown".

Anatomy [A]
Tissues [A10]
Connective Tissue [A10.165]
Adipose Tissue [A10.165.114]
Adipose Tissue, Brown [A10.165.114.322]

Below are MeSH descriptors whose meaning is related to "Adipose Tissue, Brown".

Below are MeSH descriptors whose meaning is more specific than "Adipose Tissue, Brown".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Adipose Tissue, Brown" by people in this website by year, and whether "Adipose Tissue, Brown" was a major or minor topic of these publications.

Bar chart showing 20 publications over 11 distinct years, with a maximum of 6 publications in 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
2013	1	0	1
2014	2	0	2
2015	1	0	1
2016	1	0	1
2017	1	1	2
2018	1	0	1
2019	1	1	2
2020	0	1	1
2021	3	3	6
2022	1	1	2

Below are the most recent publications written about "Adipose Tissue, Brown" by people in Profiles.

Shimada BK, Ogawa-Wong AN, Soares AG, Hallam KA, Santiago PJD, Saelua K, Nakahara-Akita KK, Torres DJ, Brockman JD, Kurokawa S, Ewell KL, Bellinger MT, Toh P, Lagatta Pamplona Remedios G, Alfulaij N, Swanson SM, Seyedali A, Zavacki AM, Berry MJ, Seale LA. Global loss of selenocysteine lyase in mice drives lipid accumulation in brown adipocytes. Am J Physiol Endocrinol Metab. 2026 02 01; 330(2):E000.

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Santiago PJD, Shimada BK, Alfulaij N, Hallam KA, Soares AG, Young V, Swanson SM, Remedios GL, Toh P, Seale LA. Targeted Disruption of Selenocysteine Lyase in Brown Adipocytes Controls Glutathione Peroxidase 1 and 4 Expression in Males. Biol Trace Elem Res. 2026 May; 204(5):3437-3450.

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Shimada BK, Watanabe LM, Swanson S, Toh P, Seale LA. Selenium and selenoproteins in thermogenic adipocytes. Arch Biochem Biophys. 2022 11 30; 731:109445.

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Yousefzadeh N, Jeddi S, Afzali H, Kashfi K, Ghasemi A. Chronic nitrate administration increases the expression the genes involved in the browning of white adipose tissue in female rats. Cell Biochem Funct. 2022 Oct; 40(7):750-759.

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Singh R, Barrios A, Dirakvand G, Pervin S. Human Brown Adipose Tissue and Metabolic Health: Potential for Therapeutic Avenues. Cells. 2021 11 05; 10(11).

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Torres DJ, Pitts MW, Seale LA, Hashimoto AC, An KJ, Hanato AN, Hui KW, Remigio SMA, Carlson BA, Hatfield DL, Berry MJ. Female Mice with Selenocysteine tRNA Deletion in Agrp Neurons Maintain Leptin Sensitivity and Resist Weight Gain While on a High-Fat Diet. Int J Mol Sci. 2021 Oct 12; 22(20).

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Tint MT, Michael N, Sadananthan SA, Huang JY, Khoo CM, Godfrey KM, Shek LP, Lek N, Tan KH, Yap F, Velan SS, Gluckman PD, Chong YS, Karnani N, Chan SY, Leow MK, Lee KJ, Lee YS, Hu HH, Zhang C, Fortier MV, Eriksson JG. Brown Adipose Tissue, Adiposity, and Metabolic Profile in Preschool Children. J Clin Endocrinol Metab. 2021 09 27; 106(10):2901-2914.

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Baskaran P, Nazminia K, Frantz J, O'Neal J, Thyagarajan B. Mice lacking endogenous TRPV1 express reduced levels of thermogenic proteins and are susceptible to diet-induced obesity and metabolic dysfunction. FEBS Lett. 2021 07; 595(13):1768-1781.

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Pervin S, Reddy ST, Singh R. Novel Roles of Follistatin/Myostatin in Transforming Growth Factor-? Signaling and Adipose Browning: Potential for Therapeutic Intervention in Obesity Related Metabolic Disorders. Front Endocrinol (Lausanne). 2021; 12:653179.

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Seale LA, Ogawa-Wong AN, Watanabe LM, Khadka VS, Menor M, Torres DJ, Carlson BA, Hatfield DL, Berry MJ. Adaptive Thermogenesis in a Mouse Model Lacking Selenoprotein Biosynthesis in Brown Adipocytes. Int J Mol Sci. 2021 Jan 09; 22(2).

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