"Antigenic Variation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Change in the surface ANTIGEN of a microorganism. There are two different types. One is a phenomenon, especially associated with INFLUENZA VIRUSES, where they undergo spontaneous variation both as slow antigenic drift and sudden emergence of new strains (antigenic shift). The second type is when certain PARASITES, especially trypanosomes, PLASMODIUM, and BORRELIA, survive the immune response of the host by changing the surface coat (antigen switching). (From Herbert et al., The Dictionary of Immunology, 4th ed)
| Descriptor ID |
D000940
|
| MeSH Number(s) |
G05.365.073 G12.500.249
|
| Concept/Terms |
Antigenic Variation- Antigenic Variation
- Antigenic Variability
- Variability, Antigenic
- Variation, Antigenic
- Antigen Variation
- Variation, Antigen
Antigen Switching- Antigen Switching
- Switching, Antigen
- Switching, Antigenic
- Antigenic Switching
|
Below are MeSH descriptors whose meaning is more general than "Antigenic Variation".
Below are MeSH descriptors whose meaning is more specific than "Antigenic Variation".
This graph shows the total number of publications written about "Antigenic Variation" by people in this website by year, and whether "Antigenic Variation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antigenic Variation" by people in Profiles.
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Kang KH, Yamamura Y, Carlos MP, Karvelas N, Kim IS, Sunkara D, Rivera R, Gardner MB, Anderson DE, Diaz-Mitoma F, Torres J, Marquez JP. Synthetic antigens representing the antigenic variation of human hepatitis C virus. Viral Immunol. 2010 Oct; 23(5):497-508.
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Kline KA, Criss AK, Wallace A, Seifert HS. Transposon mutagenesis identifies sites upstream of the Neisseria gonorrhoeae pilE gene that modulate pilin antigenic variation. J Bacteriol. 2007 May; 189(9):3462-70.
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Sechman EV, Kline KA, Seifert HS. Loss of both Holliday junction processing pathways is synthetically lethal in the presence of gonococcal pilin antigenic variation. Mol Microbiol. 2006 Jul; 61(1):185-93.
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Criss AK, Kline KA, Seifert HS. The frequency and rate of pilin antigenic variation in Neisseria gonorrhoeae. Mol Microbiol. 2005 Oct; 58(2):510-9.
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Daum LT, Shaw MW, Klimov AI, Canas LC, Macias EA, Niemeyer D, Chambers JP, Renthal R, Shrestha SK, Acharya RP, Huzdar SP, Rimal N, Myint KS, Gould P. Influenza A (H3N2) outbreak, Nepal. Emerg Infect Dis. 2005 Aug; 11(8):1186-91.
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Lopez-Ribot JL, McAtee RK, Kirkpatrick WR, La Valle R, Patterson TF. Low levels of antigenic variability in fluconazole-susceptible and -resistant Candida albicans isolates from human immunodeficiency virus-infected patients with oropharyngeal candidiasis. Clin Diagn Lab Immunol. 1999 Sep; 6(5):665-70.
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Riley JP, Pestano GA, Harewood K, Alfred LJ, Guyden J, Boto WM. Distribution of linear antigenic epitopes on GP120 encoded in sibling clones of novel New York HIV-1 subtype B isolates. Cell Mol Biol (Noisy-le-grand). 1995; 41 Suppl 1:S83-91.
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Lazo A, Bailer RT, Blakeslee JR, Yanagihara R, Stevens VC, Kramer L, Lairmore MD. Immune recognition of genetically diverse simian T-cell lymphotropic virus type I isolates. Arch Virol. 1995; 140(2):307-23.
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MacLachlan NJ, Rossitto PV, Heidner HW, Iezzi LG, Yilma TD, DeMaula CD, Osburn BI. Variation amongst the neutralizing epitopes of bluetongue viruses isolated in the United States in 1979-1981. Vet Microbiol. 1992 Jun 15; 31(4):303-16.
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Huang SY, Perez JC, Rael ED, Lieb C, Martinez M, Smith SA. Variation in the antigenic characteristics of venom from the Mojave rattlesnake (Crotalus scutulatus scutulatus). Toxicon. 1992 Apr; 30(4):387-96.