Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity.

Descriptor ID	D000276
MeSH Number(s)	D27.505.696.477.067
Concept/Terms	Adjuvants, Immunologic Adjuvants, Immunologic Immunostimulants Adjuvant, Immunologic Immunologic Adjuvant Immunological Adjuvant Adjuvant, Immunological Immunoactivators Immunoadjuvants Immunologic Adjuvants Immunopotentiators Adjuvants, Immunological Immunological Adjuvants

Below are MeSH descriptors whose meaning is more general than "Adjuvants, Immunologic".

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