A NeuroD1 AAV-Based Gene Therapy for Functional Brain Repair after Ischemic Injury through In?Vivo Astrocyte-to-Neuron Conversion.

Chen YC, Ma NX, Pei ZF, Wu Z, Do-Monte FH, Keefe S, Yellin E, Chen MS, Yin JC, Lee G, Minier-Toribio A, Hu Y, Bai YT, Lee K, Quirk GJ, Chen G. A NeuroD1 AAV-Based Gene Therapy for Functional Brain Repair after Ischemic Injury through In?Vivo Astrocyte-to-Neuron Conversion. Mol Ther. 2020 01 08; 28(1):217-234.

View in: PubMed

subject areas

Action Potentials
Animals
Astrocytes
Basic Helix-Loop-Helix Transcription Factors
Brain Ischemia
Dependovirus
Disease Models, Animal
Male
Mice
Mice, Transgenic
Nerve Degeneration
Neuroglia
Neurons
Rats
Rats, Sprague-Dawley
Treatment Outcome

authors with profiles

Gregory J. Quirk

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