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Jodie Fleming

TitleAssociate Professor
Faculty RankAssociate Professor
InstitutionNorth Carolina Central University
DepartmentBiological and Biomedical Sciences
Address700 George Street
Durham NC 27707
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    Collapse Research 
    Collapse research activities and funding
    SC2CA176585     (FLEMING, JODIE MICHELLE)Sep 26, 2012 - Aug 31, 2017
    Development of a novel targeted-therapy for treatment of basal-like breast cancer
    Role: Principal Investigator

    R21CA175783     (FLEMING, JODIE MICHELLE)Sep 1, 2013 - Aug 31, 2016
    HGF signaling in African-American and Basal-like Breast Cancer
    Role: Principal Investigator

    R15CA223994     (FLEMING, JODIE MICHELLE)Feb 4, 2019 - Jan 31, 2022
    Engineering novel methods to study metastases and reduce systemic treatment toxicity in breast cancer patients
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Jones GS, Hoadley KA, Olsson LT, Hamilton AM, Bhattacharya A, Kirk EL, Tipaldos HJ, Fleming JM, Love MI, Nichols HB, Olshan AF, Troester MA. Hepatocyte growth factor pathway expression in breast cancer by race and subtype. Breast Cancer Res. 2021 08 03; 23(1):80. PMID: 34344422.
      Citations:    Fields:    
    2. Barrow MA, Martin ME, Coffey A, Andrews PL, Jones GS, Reaves DK, Parker JS, Troester MA, Fleming JM. A functional role for the cancer disparity-linked genes, CRYßB2 and CRYßB2P1, in the promotion of breast cancer. Breast Cancer Res. 2019 09 11; 21(1):105. PMID: 31511085.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    3. Yeyeodu ST, Martin ME, Reaves DK, Enders JR, Costantini LM, Fleming JM. Experimental data demonstrating the effects of silver nanoparticles on basement membrane gene and protein expression in cultured colon, mammary and bronchial epithelia. Data Brief. 2019 Oct; 26:104464. PMID: 31667234.
    4. Martin ME, Reaves DK, Jeffcoat B, Enders JR, Costantini LM, Yeyeodu ST, Botta D, Kavanagh TJ, Fleming JM. Silver nanoparticles alter epithelial basement membrane integrity, cell adhesion molecule expression, and TGF-ß1 secretion. Nanomedicine. 2019 10; 21:102070. PMID: 31351238.
      Citations: 3     Fields:    Translation:HumansCells
    5. Fleming JM, Yeyeodu ST, McLaughlin A, Schuman D, Taylor DK. In Situ Drug Delivery to Breast Cancer-Associated Extracellular Matrix. ACS Chem Biol. 2018 10 19; 13(10):2825-2840. PMID: 30183254.
      Citations: 4     Fields:    Translation:HumansCells
    6. Parada H, Sun X, Fleming JM, Williams-DeVane CR, Kirk EL, Olsson LT, Perou CM, Olshan AF, Troester MA. Race-associated biological differences among luminal A and basal-like breast cancers in the Carolina Breast Cancer Study. Breast Cancer Res. 2017 Dec 11; 19(1):131. PMID: 29228969.
      Citations: 16     Fields:    Translation:HumansPHPublic Health
    7. Oladapo HO, Tarpley M, Sauer SJ, Addo KA, Ingram SM, Strepay D, Ehe BK, Chdid L, Trinkler M, Roques JR, Darr DB, Fleming JM, Devi GR, Williams KP. Pharmacological targeting of GLI1 inhibits proliferation, tumor emboli formation and in vivo tumor growth of inflammatory breast cancer cells. Cancer Lett. 2017 12 28; 411:136-149. PMID: 28965853.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    8. Bruno RD, Fleming JM, George AL, Boulanger CA, Schedin P, Smith GH. Mammary extracellular matrix directs differentiation of testicular and embryonic stem cells to form functional mammary glands in vivo. Sci Rep. 2017 01 10; 7:40196. PMID: 28071703.
      Citations: 12     Fields:    Translation:AnimalsCells
    9. Reaves DK, Hoadley KA, Fagan-Solis KD, Jima DD, Bereman M, Thorpe L, Hicks J, McDonald D, Troester MA, Perou CM, Fleming JM. Nuclear Localized LSR: A Novel Regulator of Breast Cancer Behavior and Tumorigenesis. Mol Cancer Res. 2017 02; 15(2):165-178. PMID: 27856957.
      Citations: 8     Fields:    Translation:HumansAnimals
    10. Reaves DK, Ginsburg E, Bang JJ, Fleming JM. Persistent organic pollutants and obesity: are they potential mechanisms for breast cancer promotion? Endocr Relat Cancer. 2015 Apr; 22(2):R69-86. PMID: 25624167.
      Citations: 13     Fields:    Translation:HumansAnimalsPHPublic Health
    11. Stiles BG, Pradhan K, Fleming JM, Samy RP, Barth H, Popoff MR. Clostridium and bacillus binary enterotoxins: bad for the bowels, and eukaryotic being. Toxins (Basel). 2014 Sep 05; 6(9):2626-56. PMID: 25198129.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    12. Fagan-Solis KD, Reaves DK, Rangel MC, Popoff MR, Stiles BG, Fleming JM. Challenging the roles of CD44 and lipolysis stimulated lipoprotein receptor in conveying Clostridium perfringens iota toxin cytotoxicity in breast cancer. Mol Cancer. 2014 Jul 02; 13:163. PMID: 24990559.
      Citations: 7     Fields:    Translation:HumansCells
    13. Reaves DK, Fagan-Solis KD, Dunphy K, Oliver SD, Scott DW, Fleming JM. The role of lipolysis stimulated lipoprotein receptor in breast cancer and directing breast cancer cell behavior. PLoS One. 2014; 9(3):e91747. PMID: 24637461.
      Citations: 16     Fields:    Translation:HumansCells
    14. Casbas-Hernandez P, D'Arcy M, Roman-Perez E, Brauer HA, McNaughton K, Miller SM, Chhetri RK, Oldenburg AL, Fleming JM, Amos KD, Makowski L, Troester MA. Role of HGF in epithelial-stromal cell interactions during progression from benign breast disease to ductal carcinoma in situ. Breast Cancer Res. 2013; 15(5):R82. PMID: 24025166.
      Citations: 25     Fields:    Translation:HumansCells
    15. Fleming JM, Ginsburg E, McAndrew CW, Heger CD, Cheston L, Rodriguez-Canales J, Vonderhaar BK, Goldsmith P. Characterization of ?7/11, a functional prolactin-binding protein. J Mol Endocrinol. 2013 Feb; 50(1):79-90. PMID: 23048206.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    16. Fleming JM, Miller TC, Kidacki M, Ginsburg E, Stuelten CH, Stewart DA, Troester MA, Vonderhaar BK. Paracrine interactions between primary human macrophages and human fibroblasts enhance murine mammary gland humanization in vivo. Breast Cancer Res. 2012 Jun 25; 14(3):R97. PMID: 22731827.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    17. Fleming JM, Ginsburg E, Oliver SD, Goldsmith P, Vonderhaar BK. Hornerin, an S100 family protein, is functional in breast cells and aberrantly expressed in breast cancer. BMC Cancer. 2012 Jun 22; 12:266. PMID: 22727333.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    18. Fleming JM, Ginsburg E, Goldhar AS, Plant J, Vonderhaar BK. Progesterone receptor activates Msx2 expression by downregulating TNAP/Akp2 and activating the Bmp pathway in EpH4 mouse mammary epithelial cells. PLoS One. 2012; 7(3):e34058. PMID: 22457812.
      Citations: 2     Fields:    Translation:AnimalsCells
    19. Casbas-Hernandez P, Fleming JM, Troester MA. Gene expression analysis of in vitro cocultures to study interactions between breast epithelium and stroma. J Biomed Biotechnol. 2011; 2011:520987. PMID: 22203785.
      Citations: 20     Fields:    Translation:HumansCells
    20. Fleming JM, Miller TC, Meyer MJ, Ginsburg E, Vonderhaar BK. Local regulation of human breast xenograft models. J Cell Physiol. 2010 Sep; 224(3):795-806. PMID: 20578247.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    21. Fleming JM, Miller TC, Quinones M, Xiao Z, Xu X, Meyer MJ, Ginsburg E, Veenstra TD, Vonderhaar BK. The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo. BMC Med. 2010 May 21; 8:27. PMID: 20492690.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    22. Meyer MJ, Fleming JM, Lin AF, Hussnain SA, Ginsburg E, Vonderhaar BK. CD44posCD49fhiCD133/2hi defines xenograft-initiating cells in estrogen receptor-negative breast cancer. Cancer Res. 2010 Jun 01; 70(11):4624-33. PMID: 20484027.
      Citations: 76     Fields:    Translation:HumansAnimals
    23. Meyer MJ, Fleming JM, Ali MA, Pesesky MW, Ginsburg E, Vonderhaar BK. Dynamic regulation of CD24 and the invasive, CD44posCD24neg phenotype in breast cancer cell lines. Breast Cancer Res. 2009; 11(6):R82. PMID: 19906290.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    24. Fleming JM, Brandimarto JA, Cohick WS. The mitogen-activated protein kinase pathway tonically inhibits both basal and IGF-I-stimulated IGF-binding protein-5 production in mammary epithelial cells. J Endocrinol. 2007 Aug; 194(2):349-59. PMID: 17641284.
      Citations: 3     Fields:    Translation:AnimalsCells
    25. Fleming JM, Desury G, Polanco TA, Cohick WS. Insulin growth factor-I and epidermal growth factor receptors recruit distinct upstream signaling molecules to enhance AKT activation in mammary epithelial cells. Endocrinology. 2006 Dec; 147(12):6027-35. PMID: 16990343.
      Citations: 3     Fields:    Translation:AnimalsCells
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