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Jorge A. Espinoza-Derout, PhD

TitleAssistant Professor
Faculty RankAssistant Professor
InstitutionCharles R. Drew University of Medicine and Science
DepartmentInternal Medicine
Address1731 E. 120th Street
1731 E. 120th Street
Los Angeles CA 90059
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Rivera JC, Espinoza-Derout J, Hasan KM, Molina-Mancio J, Mart?nez J, Lao CJ, Lee ML, Lee DL, Wilson J, Sinha-Hikim AP, Friedman TC. Hepatic steatosis induced by nicotine plus Coca-Cola? is prevented by nicotinamide riboside (NR). Front Endocrinol (Lausanne). 2024; 15:1282231. PMID: 38756999.
      Citations:    Fields:    Translation:Animals
    2. Espinoza-Derout J, Arambulo JML, Ramirez-Trillo W, Rivera JC, Hasan KM, Lao CJ, Jordan MC, Shao XM, Roos KP, Sinha-Hikim AP, Friedman TC. The lipolysis inhibitor acipimox reverses the cardiac phenotype induced by electronic cigarettes. Sci Rep. 2023 10 25; 13(1):18239. PMID: 37880325.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Hasan KM, Parveen M, Pena A, Bautista F, Rivera JC, Huerta RR, Martinez E, Espinoza-Derout J, Sinha-Hikim AP, Friedman TC. Fatty Acid Excess Dysregulates CARF to Initiate the Development of Hepatic Steatosis. Cells. 2023 04 01; 12(7). PMID: 37048142.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Espinoza-Derout J, Shao XM, Lao CJ, Hasan KM, Rivera JC, Jordan MC, Echeverria V, Roos KP, Sinha-Hikim AP, Friedman TC. Electronic Cigarette Use and the Risk of Cardiovascular Diseases. Front Cardiovasc Med. 2022; 9:879726. PMID: 35463745.
      Citations:    
    5. Hasan KM, Munoz A, Tumoyan H, Parveen M, Espinoza-Derout J, Shao XM, Mahata SK, Friedman TC, Sinha-Hikim AP. Adverse effects of fetal exposure of electronic-cigarettes and high-fat diet on male neonatal hearts. Exp Mol Pathol. 2021 02; 118:104573. PMID: 33212125.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Hasan KM, Friedman TC, Parveen M, Espinoza-Derout J, Bautista F, Razipour MM, Shao XM, Jordan MC, Roos KP, Mahata SK, Sinha-Hikim AP. Electronic cigarettes cause alteration in cardiac structure and function in diet-induced obese mice. PLoS One. 2020; 15(10):e0239671. PMID: 33002059.
      Citations: 10     Fields:    Translation:Animals
    7. Shao XM, Lopez B, Nathan D, Wilson J, Bankole E, Tumoyan H, Munoz A, Espinoza-Derout J, Hasan KM, Chang S, Du C, Sinha-Hikim AP, Lutfy K, Friedman TC. A mouse model for chronic intermittent electronic cigarette exposure exhibits nicotine pharmacokinetics resembling human vapers. J Neurosci Methods. 2019 10 01; 326:108376. PMID: 31361999.
      Citations: 22     Fields:    Translation:Animals
    8. Espinoza-Derout J, Hasan KM, Shao XM, Jordan MC, Sims C, Lee DL, Sinha S, Simmons Z, Mtume N, Liu Y, Roos KP, Sinha-Hikim AP, Friedman TC. Chronic intermittent electronic cigarette exposure induces cardiac dysfunction and atherosclerosis in apolipoprotein-E knockout mice. Am J Physiol Heart Circ Physiol. 2019 08 01; 317(2):H445-H459. PMID: 31172811.
      Citations: 42     Fields:    Translation:AnimalsCellsPHPublic Health
    9. Espinoza-Derout J, Shao XM, Bankole E, Hasan KM, Mtume N, Liu Y, Sinha-Hikim AP, Friedman TC. Hepatic DNA Damage Induced by Electronic Cigarette Exposure Is Associated With the Modulation of NAD+/PARP1/SIRT1 Axis. Front Endocrinol (Lausanne). 2019; 10:320. PMID: 31214115.
      Citations: 14     Fields:    
    10. Hasan KM, Friedman TC, Shao X, Parveen M, Sims C, Lee DL, Espinoza-Derout J, Sinha-Hikim I, Sinha-Hikim AP. E-cigarettes and Western Diet: Important Metabolic Risk Factors for Hepatic Diseases. Hepatology. 2019 06; 69(6):2442-2454. PMID: 30664268.
      Citations: 20     Fields:    Translation:HumansAnimals
    11. Hasan MK, Friedman TC, Sims C, Lee DL, Espinoza-Derout J, Ume A, Chalfant V, Lee ML, Sinha-Hikim I, Lutfy K, Liu Y, Mahata SK, Sinha-Hikim AP. a7-Nicotinic Acetylcholine Receptor Agonist Ameliorates Nicotine Plus High-Fat Diet-Induced Hepatic Steatosis in Male Mice by Inhibiting Oxidative Stress and Stimulating AMPK Signaling. Endocrinology. 2018 02 01; 159(2):931-944. PMID: 29272360.
      Citations: 13     Fields:    Translation:AnimalsCells
    12. Sinha-Hikim I, Friedman TC, Falz M, Chalfant V, Hasan MK, Espinoza-Derout J, Lee DL, Sims C, Tran P, Mahata SK, Sinha-Hikim AP. Nicotine plus a high-fat diet triggers cardiomyocyte apoptosis. Cell Tissue Res. 2017 04; 368(1):159-170. PMID: 27917437.
      Citations: 14     Fields:    Translation:AnimalsCells
    13. Huang J, Guo J, Beigi F, Hodgkinson CP, Facundo HT, Zhang Z, Espinoza-Derout J, Zhou X, Pratt RE, Mirotsou M, Dzau VJ. HASF is a stem cell paracrine factor that activates PKC epsilon mediated cytoprotection. J Mol Cell Cardiol. 2014 Jan; 66:157-64. PMID: 24269490.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    14. Li DK, Tisdale S, Espinoza-Derout J, Saieva L, Lotti F, Pellizzoni L. A cell system for phenotypic screening of modifiers of SMN2 gene expression and function. PLoS One. 2013; 8(8):e71965. PMID: 23967270.
      Citations: 9     Fields:    Translation:AnimalsCells
    15. Espinoza-Derout J, Wagner M, Salciccioli L, Lazar JM, Bhaduri S, Mascareno E, Chaqour B, Siddiqui MA. Positive transcription elongation factor b activity in compensatory myocardial hypertrophy is regulated by cardiac lineage protein-1. Circ Res. 2009 Jun 19; 104(12):1347-54. PMID: 19443839.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    16. Espinoza-Derout J, Wagner M, Shahmiri K, Mascareno E, Chaqour B, Siddiqui MA. Pivotal role of cardiac lineage protein-1 (CLP-1) in transcriptional elongation factor P-TEFb complex formation in cardiac hypertrophy. Cardiovasc Res. 2007 Jul 01; 75(1):129-38. PMID: 17459355.
      Citations: 17     Fields:    Translation:AnimalsCells
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