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Luis M. Vilá
Title Chief and Program Director of Rheumatology
Faculty Rank Professor of Medicine
Degree M.D.
Institution University of Puerto Rico
Department Rheumatology
Clusters Infectious and Immunological Diseases
Address
UPR-Medical Sciences Campus
School of Medicine
P.O. Box 365067
City San Juan
State PR
Postal Code 00936
Telephone (787)758-2525 xt 1825
Fax
Email
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  Area of Expertise: Clinical Research in Systemic lupus erythematosus.

For more information, please visit: http://md.rcm.upr.edu/rai/allergy-immunology-section/faculty/luis-m-vila-md/ .

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1. Cruz-Pérez F, Vilá S, Ríos G, Vilá LM. Efficacy of Cyclosporine in the Induction and Maintenance of Remission in a Systemic Lupus Erythematosus Patient Presenting with Macrophage-Activating Syndrome. Case Rep Rheumatol. 2018; 2018:1961585.
2. Varela-Rosario N, Arroyo-Ávila M, Fred-Jiménez RM, Díaz-Correa LM, Pérez-Ríos N, Rodríguez N, Ríos G, Vilá LM. Long-Term Outcomes in Puerto Ricans with Rheumatoid Arthritis (RA) Receiving Early Treatment with Disease-Modifying Anti-Rheumatic Drugs using the American College of Rheumatology Definition of Early RA. Open Rheumatol J. 2017; 11:136-144.
3. Montes-Rivera G, Ríos G, Vilá LM. Efficacy of Rituximab in a Systemic Lupus Erythematosus Patient Presenting with Diffuse Alveolar Hemorrhage. Case Rep Rheumatol. 2017; 2017:6031053.
4. Langefeld CD, Ainsworth HC, Cunninghame Graham DS, Kelly JA, Comeau ME, Marion MC, Howard TD, Ramos PS, Croker JA, Morris DL, Sandling JK, Almlöf JC, Acevedo-Vásquez EM, Alarcón GS, Babini AM, Baca V, Bengtsson AA, Berbotto GA, Bijl M, Brown EE, Brunner HI, Cardiel MH, Catoggio L, Cervera R, Cucho-Venegas JM, Dahlqvist SR, D'Alfonso S, Da Silva BM, de la Rúa Figueroa I, Doria A, Edberg JC, Endreffy E, Esquivel-Valerio JA, Fortin PR, Freedman BI, Frostegård J, García MA, de la Torre IG, Gilkeson GS, Gladman DD, Gunnarsson I, Guthridge JM, Huggins JL, James JA, Kallenberg CGM, Kamen DL, Karp DR, Kaufman KM, Kottyan LC, Kovács L, Laustrup H, Lauwerys BR, Li QZ, Maradiaga-Ceceña MA, Martín J, McCune JM, McWilliams DR, Merrill JT, Miranda P, Moctezuma JF, Nath SK, Niewold TB, Orozco L, Ortego-Centeno N, Petri M, Pineau CA, Pons-Estel BA, Pope J, Raj P, Ramsey-Goldman R, Reveille JD, Russell LP, Sabio JM, Aguilar-Salinas CA, Scherbarth HR, Scorza R, Seldin MF, Sjöwall C, Svenungsson E, Thompson SD, Toloza SMA, Truedsson L, Tusié-Luna T, Vasconcelos C, Vilá LM, Wallace DJ, Weisman MH, Wither JE, Bhangale T, Oksenberg JR, Rioux JD, Gregersen PK, Syvänen AC, Rönnblom L, Criswell LA, Jacob CO, Sivils KL, Tsao BP, Schanberg LE, Behrens TW, Silverman ED, Alarcón-Riquelme ME, Kimberly RP, Harley JB, Wakeland EK, Graham RR, Gaffney PM, Vyse TJ. Transancestral mapping and genetic load in systemic lupus erythematosus. Nat Commun. 2017 07 17; 8:16021.
5. Gago R, Shum LM, Vilá LM. Right upper quadrant abdominal pain as the initial presentation of polyarteritis nodosa. BMJ Case Rep. 2017 Feb 22; 2017.
6. Arroyo-Ávila M, Cabán A, García-Rivera EJ, Irizarry-Pérez M, Torres H, Gorbea H, Vilá LM. Clinical Manifestations Associated with Peripheral Joint Involvement in Patients with Acute Chikungunya Virus Infection. Am J Trop Med Hyg. 2017 Apr; 96(4):916-921.
7. Zuo Y, Willis R, Papalardo E, Petri M, Harris EN, Schleh A, DeCeulaer K, Smikle M, Vilá LM, Reveille JD, Alarcón GS, Gonzalez EB. A unique antiphospholipid assay recognizing phospholipid mixture compared with criteria antiphospholipid immunoassays in lupus patients. Lupus. 2017 May; 26(6):606-615.
8. Rodríguez-Rivera DV, Rodríguez-Navedo Y, Nieves-Plaza M, Vilá LM. Patient-reported outcome measures in a population of medically indigent patients with systemic lupus erythematosus in Puerto Rico. SAGE Open Med. 2016; 4:2050312116670927.
9. Ugarte-Gil MF, Pimentel-Quiroz VR, Vilá LM, Reveille JD, McGwin G, Alarcón GS. Factors associated with disease expression patterns in systemic lupus erythematosus patients: results from LUMINA (LXXVII), a multiethnic US cohort. Lupus. 2017 May; 26(6):650-655.
10. Gamarra-Hilburn CF, Rios G, Vilá LM. Olecranon Bursitis Caused by Candida parapsilosis in a Patient with Rheumatoid Arthritis. Case Rep Rheumatol. 2016; 2016:2019250.
11. Vázquez-Sanabria IL, Vilá LM. Sustained Improvement of Fibromyalgia Syndrome After Electroconvulsive Therapy for Intractable Depression. J Clin Rheumatol. 2016 Aug; 22(5):289-90.
12. Varela-Rosario N, Pérez-Berenguer JL, Vilá LM. Efficacy of immunosuppressive treatment in a systemic lupus erythematosus patient presenting with inclusion body myositis. BMJ Case Rep. 2016 Apr 05; 2016.
13. Deng Y, Zhao J, Sakurai D, Sestak AL, Osadchiy V, Langefeld CD, Kaufman KM, Kelly JA, James JA, Petri MA, Bae SC, Alarcón-Riquelme ME, Alarcón GS, Anaya JM, Criswell LA, Freedman BI, Kamen DL, Gilkeson GS, Jacob CO, Merrill JT, Gaffney PM, Sivils KM, Niewold TB, Ramsey-Goldman R, Reveille JD, Scofield RH, Stevens AM, Boackle SA, Vilá LM, Sohn II, Lee S, Chang DM, Song YW, Vyse TJ, Harley JB, Brown EE, Edberg JC, Kimberly RP, Cantor RM, Hahn BH, Grossman JM, Tsao BP. Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production. Ann Rheum Dis. 2016 Nov; 75(11):2007-2013.
14. Fred-Jiménez RM, Arroyo-Ávila M, Mayor ÁM, Ríos G, Vilá LM. Clinical Manifestations Associated with Overweight/Obesity in Puerto Ricans with Fibromyalgia Syndrome. J Obes. 2016; 2016:1379289.
15. Arroyo-Ávila M, Vilá LM. Reply: To PMID 26710364. P R Health Sci J. 2015 Dec; 34(4):232.
16. Zhao J, Wu H, Langefeld CD, Kaufman KM, Kelly JA, Bae SC. Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus. Clin Immunol. 2015 Dec; 161(2):157-62.
17. Vázquez-Sanabria IL, Mercado-Seda R, Varela-Rosario N, Vilá LM. Efficacy of intravenous immunoglobulins in a patient with systemic lupus erythematosus presenting with Stevens-Johnson syndrome. BMJ Case Rep. 2015 Jul 22; 2015.
18. Arroyo-Ávila M, Vilá LM. Rheumatic Manifestations in Patients with Chikungunya Infection. P R Health Sci J. 2015 Jun; 34(2):71-7.
19. Arroyo-Ávila M, Santiago-Casas Y, McGwin G, Cantor RS, Petri M, Ramsey-Goldman R, Reveille JD, Kimberly RP, Alarcón GS, Vilá LM, Brown EE. Clinical associations of anti-Smith antibodies in PROFILE: a multi-ethnic lupus cohort. Clin Rheumatol. 2015 Jul; 34(7):1217-23.
20. Lu X, Zoller EE, Weirauch MT, Wu Z, Namjou B, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath SK, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Sivils KL, Criswell LA, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Joo YB, Choi J, Bae SC, Boackle SA, Graham DC, Vyse TJ, Guthridge JM, Gaffney PM, Langefeld CD, Kelly JA, Greis KD, Kaufman KM, Harley JB, Kottyan LC. Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression. Am J Hum Genet. 2015 May 07; 96(5):731-9.
21. Arroyo-Ávila M, Fred-Jiménez RM, Vilá LM. Early-onset neutropenia induced by rituximab in a patient with lupus nephritis and hemolytic anemia. Case Rep Rheumatol. 2015; 2015:616787.
22. Martins M, Williams AH, Comeau M, Marion M, Ziegler JT, Freedman BI, Merrill JT, Glenn SB, Kelly JA, Sivils KM, James JA, Guthridge JM, Alarcón-Riquelme ME, Bae SC, Kim JH, Kim D, Anaya JM, Boackle SA, Criswell LA, Kimberly RP, Alarcón GS, Brown EE, Vilá LM, Petri MA, Ramsey-Goldman R, Niewold TB, Tsao BP, Gilkeson GS, Kamen DL, Jacob CO, Stevens AM, Gaffney PM, Harley JB, Langefeld CD, Fesel C. Genetic association of CD247 (CD3?) with SLE in a large-scale multiethnic study. Genes Immun. 2015 Mar; 16(2):142-50.
23. Vaughn SE, Foley C, Lu X, Patel ZH, Zoller EE, Magnusen AF, Williams AH, Ziegler JT, Comeau ME, Marion MC, Glenn SB, Adler A, Shen N, Nath S, Stevens AM, Freedman BI, Tsao BP, Jacob CO, Kamen DL, Brown EE, Gilkeson GS, Alarcón GS, Reveille JD, Anaya JM, James JA, Moser KL, Criswell LA, Vilá LM, Alarcón-Riquelme ME, Petri M, Scofield RH, Kimberly RP, Ramsey-Goldman R, Binjoo Y, Choi J, Bae SC, Boackle SA, Vyse TJ, Guthridge JM, Namjou B, Gaffney PM, Langefeld CD, Kaufman KM, Kelly JA, Harley IT, Harley JB, Kottyan LC. Lupus risk variants in the PXK locus alter B-cell receptor internalization. Front Genet. 2014; 5:450.
24. Arroyo-Ávila M, Vilá LM. Cardiac tamponade in a patient with mixed connective tissue disease. J Clin Rheumatol. 2015 Jan; 21(1):42-5.
25. Arroyo-Ávila M, Vilá LM. Limited systemic sclerosis initially presenting with mesenteric panniculitis. BMJ Case Rep. 2014 Oct 17; 2014.
26. Díaz-Correa LM, de León-Tellado N, Ríos G, Vilá LM. Granulomatosis with polyangiitis complicated with bronchopleural fistula. BMJ Case Rep. 2014 Sep 23; 2014.
27. Kottyan LC, Zoller EE, Bene J, Lu X, Kelly JA, Rupert AM, Lessard CJ, Vaughn SE, Marion M, Weirauch MT, Namjou B, Adler A, Rasmussen A, Glenn S, Montgomery CG, Hirschfield GM, Xie G, Coltescu C, Amos C, Li H, Ice JA, Nath SK, Mariette X, Bowman S. The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share. Hum Mol Genet. 2015 Jan 15; 24(2):582-96.
28. Ríos G, Estrada M, Mayor AM, Vilá LM. Factors associated with tender point count in Puerto Ricans with fibromyalgia syndrome. P R Health Sci J. 2014 Sep; 33(3):112-6.
29. Zhao J, Giles BM, Taylor RL, Yette GA, Lough KM, Ng HL, Abraham LJ, Wu H, Kelly JA, Glenn SB, Adler AJ, Williams AH, Comeau ME, Ziegler JT, Marion M, Alarcón-Riquelme ME. Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA. Ann Rheum Dis. 2016 Jan; 75(1):242-52.
30. Kaiser R, Tang LF, Taylor KE, Sterba K, Nititham J, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vilá LM, Petri M, Rauch J, Miller E, Mesznik K, Kwok PY, Kimberly RP, Salmon JE, Criswell LA. A polymorphism in TLR2 is associated with arterial thrombosis in a multiethnic population of patients with systemic lupus erythematosus. Arthritis Rheumatol. 2014 Jul; 66(7):1882-7.
31. López-López L, Nieves-Plaza M, Castro Mdel R, Font YM, Torres-Ramos CA, Vilá LM, Ayala-Peña S. Mitochondrial DNA damage is associated with damage accrual and disease duration in patients with systemic lupus erythematosus. Lupus. 2014 Oct; 23(11):1133-41.
32. Dong C, Ptacek TS, Redden DT, Zhang K, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vilá LM, Petri M, Qin A, Wu J, Kimberly RP. Fc? receptor IIIa single-nucleotide polymorphisms and haplotypes affect human IgG binding and are associated with lupus nephritis in African Americans. Arthritis Rheumatol. 2014 May; 66(5):1291-9.
33. Guthridge JM, Lu R, Sun H, Sun C, Wiley GB, Dominguez N, Macwana SR, Lessard CJ, Kim-Howard X, Cobb BL, Kaufman KM, Kelly JA, Langefeld CD, Adler AJ, Harley IT, Merrill JT, Gilkeson GS, Kamen DL, Niewold TB, Brown EE, Edberg JC, Petri MA, Ramsey-Goldman R, Reveille JD, Vilá LM, Kimberly RP, Freedman BI, Stevens AM, Boackle SA, Criswell LA, Vyse TJ, Behrens TW, Jacob CO, Alarcón-Riquelme ME, Sivils KL, Choi J, Joo YB, Bang SY, Lee HS, Bae SC, Shen N, Qian X, Tsao BP, Scofield RH, Harley JB, Webb CF, Wakeland EK, James JA, Nath SK, Graham RR, Gaffney PM. Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription. Am J Hum Genet. 2014 Apr 03; 94(4):586-98.
34. Villafrádez-Díaz M, Santiago-Casas Y, Nieves-Plaza M, Morales M, Rodríguez V, Ríos G, Martínez D, Vilá LM. Association of the use of statins with disease activity and functional status in Puerto Ricans with rheumatoid arthritis. P R Health Sci J. 2014 Mar; 33(1):3-8.
35. Font YM, Castro-Santana LE, Nieves-Plaza M, Maldonado M, Mayor AM, Vilá LM. Factors associated with regional rheumatic pain disorders in a population of Puerto Ricans with diabetes mellitus. Clin Rheumatol. 2014 Jul; 33(7):995-1000.
36. Willis R, Seif AM, McGwin G, Martinez-Martinez LA, González EB, Doan E, Dang N, Papalardo E, Liu J, Vilá LM, Reveille JD, Alarcón GS, Pierangeli SS. Effects of statins on proinflammatory/prothrombotic biomarkers and on disease activity scores in SLE patients: data from LUMINA (LXXVI), a multi-ethnic US cohort. Clin Exp Rheumatol. 2014 Mar-Apr; 32(2):162-7.
37. Ojeda J, López-López L, González A, Vilá LM. Infective endocarditis initially presenting with a dermatomyositis-like syndrome. BMJ Case Rep. 2014 Jan 10; 2014.
38. Díaz-Correa LM, Ramírez-García LM, Castro-Santana LE, Vilá LM. Osteoporosis knowledge in patients with a first fragility fracture in Puerto Rico. Bol Asoc Med P R. 2014; 106(1):6-10.
39. Murthy V, Willis R, Romay-Penabad Z, Ruiz-Limón P, Martínez-Martínez LA, Jatwani S, Jajoria P, Seif A, Alarcón GS, Papalardo E, Liu J, Vilá LM, McGwin G, McNearney TA, Maganti R, Sunkureddi P, Parekh T, Tarantino M, Akhter E, Fang H, Gonzalez EB, Binder WR, Norman GL, Shums Z, Teodorescu M, Reveille JD, Petri M, Pierangeli SS. Value of isolated IgA anti-ß2 -glycoprotein I positivity in the diagnosis of the antiphospholipid syndrome. Arthritis Rheum. 2013 Dec; 65(12):3186-93.
40. Fajardo-Hermosillo LD, Rodríguez-Navedo Y, Nadal AJ, Vilá LM. Lymphocyte sensitivity assay as a marker for glucocorticoid resistance in lupus: report of two sisters with systemic lupus erythematosus. Lupus. 2014; 23(1):88-92.
41. Sakurai D, Zhao J, Deng Y, Kelly JA, Brown EE, Harley JB, Bae SC, Alarc?n-Riquelme ME. Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression. PLoS Genet. 2013; 9(10):e1003870.
42. Caster DJ, Korte EA, Nanda SK, McLeish KR, Oliver RK, G'sell RT, Sheehan RM, Freeman DW, Coventry SC, Kelly JA, Guthridge JM, James JA, Sivils KL, Alarcon-Riquelme ME, Scofield RH, Adrianto I, Gaffney PM, Stevens AM, Freedman BI, Langefeld CD, Tsao BP, Pons-Estel BA, Jacob CO, Kamen DL, Gilkeson GS, Brown EE, Alarcon GS, Edberg JC, Kimberly RP, Martin J, Merrill JT, Harley JB, Kaufman KM, Reveille JD, Anaya JM, Criswell LA, Vila LM, Petri M, Ramsey-Goldman R, Bae SC, Boackle SA, Vyse TJ, Niewold TB, Cohen P, Powell DW. ABIN1 dysfunction as a genetic basis for lupus nephritis. J Am Soc Nephrol. 2013 Nov; 24(11):1743-54.
43. Namjou B, Kim-Howard X, Sun C, Adler A, Chung SA, Kaufman KM, Kelly JA, Glenn SB, Guthridge JM, Scofield RH, Kimberly RP, Brown EE, Alarcón GS, Edberg JC, Kim JH, Choi J, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Boackle SA, Freedman BI, Tsao BP, Langefeld CD, Vyse TJ, Jacob CO, Pons-Estel B. PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes. PLoS One. 2013; 8(8):e69404.
44. Jiménez-Encarnación E, Vilá LM. Recurrent venous thrombosis in Ehlers-Danlos syndrome type III: an atypical manifestation. BMJ Case Rep. 2013 Jun 27; 2013.
45. Rodríguez-Pérez N, Rodríguez-Navedo Y, Font YM, Vilá LM. Inflammatory myopathy as the initial presentation of cryoglobulinaemic vasculitis. BMJ Case Rep. 2013 Jun 03; 2013.
46. Ramos PS, Oates JC, Kamen DL, Williams AH, Gaffney PM, Kelly JA, Kaufman KM, Kimberly RP, Niewold TB, Jacob CO, Tsao BP, Alarcón GS, Brown EE, Edberg JC, Petri MA, Ramsey-Goldman R, Reveille JD, Vilá LM, James JA, Guthridge JM, Merrill JT, Boackle SA, Freedman BI, Scofield RH, Stevens AM, Vyse TJ, Criswell LA, Moser KL, Alarcón-Riquelme ME, Langefeld CD, Harley JB, Gilkeson GS. Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry. J Rheumatol. 2013 Jun; 40(6):842-9.
47. Fajardo-Hermosillo LD, López-López L, Nadal A, Vilá LM. Multifocal osteonecrosis in systemic lupus erythematosus: case report and review of the literature. BMJ Case Rep. 2013 Apr 16; 2013.
48. Jolly M, Toloza S, Block J, Mikolaitis R, Kosinski M, Wallace D, Durran-Barragan S, Bertoli A, Blazevic I, Vilá L, Cooray D, Moldovan I, Katsaros E, Weisman M, Torralba KM, Alarcón G. Spanish LupusPRO: cross-cultural validation study for lupus. Lupus. 2013 Apr; 22(5):431-6.
49. Negrón AM, Díaz-Correa LM, Gago R, Mayor AM, Martínez A, Vilá S, Vilá LM. Rheumatology practice profiles in teaching and community settings in Puerto Rico: implications to subspecialty training. J Clin Rheumatol. 2013 Mar; 19(2):67-71.
50. Santiago-Casas Y, Peredo RA, Vilá LM. Efficacy of low-dose intravenous cyclophosphamide in systemic lupus erythematosus presenting with Guillain-Barre syndrome-like acute axonal neuropathies: report of two cases. Lupus. 2013 Mar; 22(3):324-7.
51. Deng Y, Zhao J, Sakurai D, Kaufman KM, Edberg JC, Kimberly RP, Kamen DL, Gilkeson GS, Jacob CO, Scofield RH, Langefeld CD, Kelly JA, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Alarcón GS, Vyse TJ, Pons-Estel BA. MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus. PLoS Genet. 2013; 9(2):e1003336.
52. Molineros JE, Maiti AK, Sun C, Looger LL, Han S, Kim-Howard X, Glenn S, Adler A, Kelly JA, Niewold TB, Gilkeson GS, Brown EE, Alarcón GS, Edberg JC, Petri M, Ramsey-Goldman R, Reveille JD, Vilá LM, Freedman BI, Tsao BP, Criswell LA, Jacob CO, Moore JH, Vyse TJ, Langefeld CL, Guthridge JM, Gaffney PM, Moser KL, Scofield RH, Alarcón-Riquelme ME. Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production. PLoS Genet. 2013; 9(2):e1003222.
53. Santiago-Casas Y, González-Rivera T, Castro-Santana L, Ríos G, Martínez D, Rodríguez V, González-Alcover R, Mayor AM, Vilá LM. Impact of managed care health insurance system for indigent patients with rheumatoid arthritis in Puerto Rico. Clin Rheumatol. 2013 Jun; 32(6):763-9.
54. Nieves-Plaza M, Castro-Santana LE, Font YM, Mayor AM, Vilá LM. Association of hand or knee osteoarthritis with diabetes mellitus in a population of Hispanics from Puerto Rico. J Clin Rheumatol. 2013 Jan; 19(1):1-6.
55. Kaiser R, Taylor KE, Deng Y, Zhao J, Li Y, Nititham J, Chang M, Catanese J, Begovich AB, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vila LM, Petri M, Kimberly RP, Feng X, Sun L, Shen N, Li W, Lu JX, Wakeland EK, Li QZ, Yang W, Lau YL, Liu FL, Chang DM, Yu CY, Song YW, Tsao BP, Criswell LA. Brief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians. Arthritis Rheum. 2013 Jan; 65(1):211-5.
56. Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep. 2012 Dec 19; 2012.
57. Adrianto I, Wang S, Wiley GB, Lessard CJ, Kelly JA, Adler AJ, Glenn SB, Williams AH, Ziegler JT, Comeau ME, Marion MC, Wakeland BE, Liang C, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME. Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus. Arthritis Rheum. 2012 Nov; 64(11):3695-705.
58. Sánchez E, Rasmussen A, Riba L, Acevedo-Vasquez E, Kelly JA, Langefeld CD, Williams AH, Ziegler JT, Comeau ME, Marion MC, García-De La Torre I, Maradiaga-Ceceña MA, Cardiel MH, Esquivel-Valerio JA, Rodriguez-Amado J, Moctezuma JF, Miranda P, Perandones CE, Castel C, Laborde HA, Alba P, Musuruana JL, Goecke IA, Anaya JM, Kaufman KM, Adler A, Glenn SB, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Vilá LM, Criswell LA, Gilkeson GS, Niewold TB, Martín J, Vyse TJ, Boackle SA, Ramsey-Goldman R, Scofield RH, Petri M, Merrill JT, Reveille JD, Tsao BP, Orozco L, Baca V, Moser KL, Gaffney PM, James JA, Harley JB, Tusié-Luna T, Pons-Estel BA, Jacob CO, Alarcón-Riquelme ME. Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations. Arthritis Rheum. 2012 Nov; 64(11):3687-94.
59. López-López L, Rivera-Rodríguez N, Vilá LM. Nitrofurantoin-induced microangiopathic haemolytic anaemia and thrombocytopaenia in a patient with systemic lupus erythematosus. BMJ Case Rep. 2012 Sep 12; 2012.
60. Kaufman KM, Zhao J, Kelly JA, Hughes T, Adler A, Sanchez E, Ojwang JO, Langefeld CD, Ziegler JT, Williams AH, Comeau ME, Marion MC, Glenn SB, Cantor RM, Grossman JM, Hahn BH, Song YW, Yu CY, James JA, Guthridge JM, Brown EE, Alarcón GS, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Anaya JM, Boackle SA, Stevens AM, Freedman BI, Criswell LA, Pons Estel BA. Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups. Ann Rheum Dis. 2013 Mar; 72(3):437-44.
61. Kaiser R, Li Y, Chang M, Catanese J, Begovich AB, Brown EE, Edberg JC, McGwin G, Alarcón GS, Ramsey-Goldman R, Reveille JD, Vilá LM, Petri MA, Kimberly RP, Taylor KE, Criswell LA. Genetic risk factors for thrombosis in systemic lupus erythematosus. J Rheumatol. 2012 Aug; 39(8):1603-10.
62. Jiménez-Encarnación E, García-Pallas MV, Vilá LM. Severe leg ulcers in a multiple myeloma patient with cryoglobulinemic vasculitis. P R Health Sci J. 2012 Jun; 31(2):71.
63. Santiago-Casas Y, Vilá LM, McGwin G, Cantor RS, Petri M, Ramsey-Goldman R, Reveille JD, Kimberly RP, Alarcón GS, Brown EE. Association of discoid lupus erythematosus with clinical manifestations and damage accrual in a multiethnic lupus cohort. Arthritis Care Res (Hoboken). 2012 May; 64(5):704-12.
64. Kim K, Brown EE, Choi CB, Alarcón-Riquelme ME. Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries. Ann Rheum Dis. 2012 Nov; 71(11):1809-14.
65. Wang S, Adrianto I, Wiley GB, Lessard CJ, Kelly JA, Adler AJ, Glenn SB, Williams AH, Ziegler JT, Comeau ME, Marion MC, Wakeland BE, Liang C, Kaufman KM, Guthridge JM, Alarcón-Riquelme ME. A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus. Genes Immun. 2012 Jul; 13(5):380-7.
66. Lessard CJ, Adrianto I, Ice JA, Wiley GB, Kelly JA, Glenn SB, Adler AJ, Li H, Rasmussen A, Williams AH, Ziegler J, Comeau ME, Marion M, Wakeland BE, Liang C, Ramos PS, Grundahl KM, Gallant CJ, Alarcón-Riquelme ME, Alarcón GS, Anaya JM, Bae SC, Boackle SA, Brown EE, Chang DM, Cho SK, Criswell LA, Edberg JC, Freedman BI, Gilkeson GS, Jacob CO, James JA, Kamen DL, Kimberly RP, Kim JH, Martin J, Merrill JT, Niewold TB, Park SY, Petri MA, Pons-Estel BA, Ramsey-Goldman R, Reveille JD, Scofield RH, Song YW, Stevens AM, Tsao BP, Vila LM, Vyse TJ, Yu CY, Guthridge JM, Kaufman KM, Harley JB, Wakeland EK, Langefeld CD, Gaffney PM, Montgomery CG, Moser KL. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study. Am J Hum Genet. 2012 Apr 06; 90(4):648-60.
67. Willis R, Seif AM, McGwin G, Martinez-Martinez LA, González EB, Dang N, Papalardo E, Liu J, Vilá LM, Reveille JD, Alarcón GS, Pierangeli SS. Effect of hydroxychloroquine treatment on pro-inflammatory cytokines and disease activity in SLE patients: data from LUMINA (LXXV), a multiethnic US cohort. Lupus. 2012 Jul; 21(8):830-5.
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137. Ríos-Olivares E, Vilá LM, Reyes JC, Rodríguez JW, Colón JH, Pagán NO, Marrero A, Ríos-Orraca ZM, Boukli NM, Shapshak P, Robles RR. Impaired cytokine production and suppressed lymphocyte proliferation activity in HCV-infected cocaine and heroin ("speedball") users. Drug Alcohol Depend. 2006 Dec 01; 85(3):236-43.
138. Bastian HM, Alarcón GS, Roseman JM, McGwin G, Vilá LM, Fessler BJ, Reveille JD. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA) XL II: factors predictive of new or worsening proteinuria. Rheumatology (Oxford). 2007 Apr; 46(4):683-9.
139. Chaiamnuay S, Bertoli AM, Roseman JM, McGwin G, Apte M, Durán S, Vilá LM, Reveille JD, Alarcón GS. African-American and Hispanic ethnicities, renal involvement and obesity predispose to hypertension in systemic lupus erythematosus: results from LUMINA, a multiethnic cohort (LUMINAXLV). Ann Rheum Dis. 2007 May; 66(5):618-22.
140. Vilá LM, Alarcón GS, McGwin G, Bastian HM, Fessler BJ, Reveille JD. Systemic lupus erythematosus in a multiethnic US cohort, XXXVII: association of lymphopenia with clinical manifestations, serologic abnormalities, disease activity, and damage accrual. Arthritis Rheum. 2006 Oct 15; 55(5):799-806.
141. Colón-Soto M, Peredo RA, Vilá LM. Systemic lupus erythematosus after mesotherapy with acetyl-L-carnitine. J Clin Rheumatol. 2006 Oct; 12(5):261-2.
142. Alarcón GS, McGwin G, Petri M, Ramsey-Goldman R, Fessler BJ, Vilá LM, Edberg JC, Reveille JD, Kimberly RP. Time to renal disease and end-stage renal disease in PROFILE: a multiethnic lupus cohort. PLoS Med. 2006 Oct; 3(10):e396.
143. Alarcón GS, Calvo-Alén J, McGwin G, Uribe AG, Toloza SM, Roseman JM, Fernández M, Fessler BJ, Vilá LM, Ahn C, Tan FK, Reveille JD. Systemic lupus erythematosus in a multiethnic cohort: LUMINA XXXV. Predictive factors of high disease activity over time. Ann Rheum Dis. 2006 Sep; 65(9):1168-74.
144. Vilá LM, Molina MJ, Mayor AM, Cruz JJ, Ríos-Olivares E, Ríos Z. Association of serum MIP-1alpha, MIP-1beta, and RANTES with clinical manifestations, disease activity, and damage accrual in systemic lupus erythematosus. Clin Rheumatol. 2007 May; 26(5):718-22.
145. Andrade RM, McGwin G, Alarcón GS, Sanchez ML, Bertoli AM, Fernández M, Fessler BJ, Apte M, Arango AM, Bastian HM, Vilá LM, Reveille JD. Predictors of post-partum damage accrual in systemic lupus erythematosus: data from LUMINA, a multiethnic US cohort (XXXVIII). Rheumatology (Oxford). 2006 Nov; 45(11):1380-4.
146. Bertoli AM, Fernández M, Alarcón GS, Vilá LM, Reveille JD. Systemic lupus erythematosus in a multiethnic US cohort LUMINA (XLI): factors predictive of self-reported work disability. Ann Rheum Dis. 2007 Jan; 66(1):12-7.
147. Calvo-Alén J, Alarcón GS, Tew MB, Tan FK, McGwin G, Fessler BJ, Vilá LM, Reveille JD. Systemic lupus erythematosus in a multiethnic US cohort: XXXIV. Deficient mannose-binding lectin exon 1 polymorphisms are associated with cerebrovascular but not with other arterial thrombotic events. Arthritis Rheum. 2006 Jun; 54(6):1940-5.
148. Bertoli AM, Fernández M, McGwin G, Vilá LM, Reveille JD, Alarcón GS. Association of antioxidized low-density lipoprotein antibodies with vascular arterial events and renal manifestations in systemic lupus erythematosus patients: comment on the article by Frostegård et al. Arthritis Rheum. 2006 Jun; 54(6):2035-6.
149. Bertoli AM, Alarcón GS, Calvo-Alén J, Fernández M, Vilá LM, Reveille JD. Systemic lupus erythematosus in a multiethnic US cohort. XXXIII. Clinical [corrected] features, course, and outcome in patients with late-onset disease. Arthritis Rheum. 2006 May; 54(5):1580-7.
150. Bertoli AM, Fernández M, McGwin G, Alarcón GS, Tan FK, Reveille JD, Vilá LM. Systemic lupus erythematosus in a multiethnic US cohort: XXXVI. Influence of mannose-binding lectin exon 1 polymorphisms in disease manifestations, course, and outcome. Arthritis Rheum. 2006 May; 54(5):1703-4.
151. Bertoli AM, Alarcón GS, McGwin G, Fernández M, Bastian HM, Fessler BJ, Vilá LM, Reveille JD. Systemic lupus erythematosus in a multiethnic U.S. cohort (LUMINA) XXVII: factors predictive of a decline to low levels of disease activity. Lupus. 2006; 15(1):13-8.
152. Bertoli AM, Fernández M, Calvo-Alén J, Vilá LM, Sanchez ML, Reveille JD, Alarcón GS. Systemic lupus erythematosus in a multiethnic U.S. cohort (LUMINA) XXXI: factors associated with patients being lost to follow-up. Lupus. 2006; 15(1):19-25.
153. Alarcón GS, Bastian HM, Beasley TM, Roseman JM, Tan FK, Fessler BJ, Vilá LM, McGwin G. Systemic lupus erythematosus in a multi-ethnic cohort (LUMINA) XXXII: [corrected] contributions of admixture and socioeconomic status to renal involvement. Lupus. 2006; 15(1):26-31.
154. Fernández M, McGwin G, Bertoli AM, Calvo-Alén J, Vilá LM, Reveille JD, Alarcón GS. Discontinuation rate and factors predictive of the use of hydroxychloroquine in LUMINA, a multiethnic US cohort (LUMINA XL). Lupus. 2006; 15(10):700-4.
155. Vilá LM, Molina MJ, Mayor AM, Peredo RA, Santaella ML, Vilá S. Clinical and prognostic value of autoantibodies in puerto Ricans with systemic lupus erythematosus. Lupus. 2006; 15(12):892-8.
156. Calvo-Alén J, McGwin G, Toloza S, Fernández M, Roseman JM, Bastian HM, Cepeda EJ, González EB, Baethge BA, Fessler BJ, Vilá LM, Reveille JD, Alarcón GS. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): XXIV. Cytotoxic treatment is an additional risk factor for the development of symptomatic osteonecrosis in lupus patients: results of a nested matched case-control study. Ann Rheum Dis. 2006 Jun; 65(6):785-90.
157. Vilá LM, Alarcón GS, McGwin G, Bastian HM, Fessler BJ, Reveille JD. Systemic lupus erythematosus in a multiethnic cohort (LUMINA): XXIX. Elevation of erythrocyte sedimentation rate is associated with disease activity and damage accrual. J Rheumatol. 2005 Nov; 32(11):2150-5.
158. Ho KT, Ahn CW, Alarcón GS, Baethge BA, Tan FK, Roseman J, Bastian HM, Fessler BJ, McGwin G, Vilá LM, Calvo-Alén J, Reveille JD. Systemic lupus erythematosus in a multiethnic cohort (LUMINA): XXVIII. Factors predictive of thrombotic events. Rheumatology (Oxford). 2005 Oct; 44(10):1303-7.
159. Calvo-Alén J, Toloza SM, Fernández M, Bastian HM, Fessler BJ, Roseman JM, McGwin G, Vilá LM, Reveille JD, Alarcón GS. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA). XXV. Smoking, older age, disease activity, lupus anticoagulant, and glucocorticoid dose as risk factors for the occurrence of venous thrombosis in lupus patients. Arthritis Rheum. 2005 Jul; 52(7):2060-8.
160. Fernández M, Calvo-Alén J, Alarcón GS, Roseman JM, Bastian HM, Fessler BJ, McGwin G, Vilá LM, Sanchez ML, Reveille JD. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): XXI. Disease activity, damage accrual, and vascular events in pre- and postmenopausal women. Arthritis Rheum. 2005 Jun; 52(6):1655-64.
161. Calvo-Alén J, Vilá LM, Reveille JD, Alarcón GS. Effect of ethnicity on disease activity in systemic lupus erythematosus. J Rheumatol. 2005 May; 32(5):962-3; author reply 963.
162. Fessler BJ, Alarcón GS, McGwin G, Roseman J, Bastian HM, Friedman AW, Baethge BA, Vilá L, Reveille JD. Systemic lupus erythematosus in three ethnic groups: XVI. Association of hydroxychloroquine use with reduced risk of damage accrual. Arthritis Rheum. 2005 May; 52(5):1473-80.
163. Szalai AJ, Alarcón GS, Calvo-Alén J, Toloza SM, McCrory MA, Edberg JC, McGwin G, Bastian HM, Fessler BJ, Vilá LM, Kimberly RP, Reveille JD. Systemic lupus erythematosus in a multiethnic US Cohort (LUMINA). XXX: association between C-reactive protein (CRP) gene polymorphisms and vascular events. Rheumatology (Oxford). 2005 Jul; 44(7):864-8.
164. Alarcón GS, Beasley TM, Roseman JM, McGwin G, Fessler BJ, Bastian HM, Vilá LM, Tan F, Reveille JD. Ethnic disparities in health and disease: the need to account for ancestral admixture when estimating the genetic contribution to both (LUMINA XXVI). Lupus. 2005; 14(10):867-8.
165. Toloza SM, Uribe AG, McGwin G, Alarcón GS, Fessler BJ, Bastian HM, Vilá LM, Wu R, Shoenfeld Y, Roseman JM, Reveille JD. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA). XXIII. Baseline predictors of vascular events. Arthritis Rheum. 2004 Dec; 50(12):3947-57.
166. Uribe AG, Vilá LM, McGwin G, Sanchez ML, Reveille JD, Alarcón GS. The Systemic Lupus Activity Measure-revised, the Mexican Systemic Lupus Erythematosus Disease Activity Index (SLEDAI), and a modified SLEDAI-2K are adequate instruments to measure disease activity in systemic lupus erythematosus. J Rheumatol. 2004 Oct; 31(10):1934-40.
167. Toloza SM, Roseman JM, Alarcón GS, McGwin G, Uribe AG, Fessler BJ, Bastian HM, Vilá LM, Reveille JD. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA): XXII. Predictors of time to the occurrence of initial damage. Arthritis Rheum. 2004 Oct; 50(10):3177-86.
168. Alarcón GS, McGwin G, Roseman JM, Uribe A, Fessler BJ, Bastian HM, Friedman AW, Baethge B, Vilá LM, Reveille JD. Systemic lupus erythematosus in three ethnic groups. XIX. Natural history of the accrual of the American College of Rheumatology criteria prior to the occurrence of criteria diagnosis. Arthritis Rheum. 2004 Aug 15; 51(4):609-15.
169. Alarcón GS, McGwin G, Uribe A, Friedman AW, Roseman JM, Fessler BJ, Bastian HM, Baethge BA, Vilá LM, Reveille JD. Systemic lupus erythematosus in a multiethnic lupus cohort (LUMINA). XVII. Predictors of self-reported health-related quality of life early in the disease course. Arthritis Rheum. 2004 Jun 15; 51(3):465-74.
170. Martínez A, Vilá LM, Ríos-Olivares E. Predominance of CD4+ T cells and Th2 cytokines in the pericardial fluid of a dermatomyositis patient with cardiac tamponade. Clin Exp Rheumatol. 2004 Jan-Feb; 22(1):135.
171. Mayor AM, Vilá LM. Gender differences in a cohort of Puerto Ricans with systemic lupus erythematosus. Cell Mol Biol (Noisy-le-grand). 2003 Dec; 49(8):1339-44.
172. Vilá LM, Alarcón GS, McGwin G, Friedman AW, Baethge BA, Bastian HM, Fessler BJ, Reveille JD. Early clinical manifestations, disease activity and damage of systemic lupus erythematosus among two distinct US Hispanic subpopulations. Rheumatology (Oxford). 2004 Mar; 43(3):358-63.
173. Mayor AM, Vilá LM, De La Cruz M, Gómez R. Impact of managed care on clinical outcome of systemic lupus erythematosus in Puerto Rico. J Clin Rheumatol. 2003 Feb; 9(1):25-32.
174. Vilá LM, Mayor AM, Silvestrini IE. Therapeutic response and long-term follow-up in a systemic lupus erythematosus patient presenting with Kikuchi's disease. Lupus. 2001; 10(2):126-8.
175. Vilá LM, Mayor AM, Valentín AH, García-Soberal M, Vilá S. Clinical outcome and predictors of disease evolution in patients with incomplete lupus erythematosus. Lupus. 2000; 9(2):110-5.
176. Vilá LM, Rivera del Río JR, Ríos Z, Rivera E. Lymphocyte populations and cytokine concentrations in pericardial fluid from a systemic lupus erythematosus patient with cardiac tamponade. Ann Rheum Dis. 1999 Nov; 58(11):720-1.
177. Robles RR, Reyes JC, Colón HM, Matos TD, Vilá Pérez L, Marrero CA. Prevalence and correlates of anergy among drug users in Puerto Rico. Int J Epidemiol. 1999 Jun; 28(3):509-13.
178. Vilá LM, Mayor AM, Valentín AH, Rodríguez SI, Reyes ML, Acosta E, Vilá S. Association of sunlight exposure and photoprotection measures with clinical outcome in systemic lupus erythematosus. P R Health Sci J. 1999 Jun; 18(2):89-94.
179. Vilá LM, Mayor AM, Valentín AH, García-Soberal M, Vilá S. Clinical and immunological manifestations in 134 Puerto Rican patients with systemic lupus erythematosus. Lupus. 1999; 8(4):279-86.
180. Vilá LM, Ríos-Olivares E, Ríos Z, Meléndez M, García M, Pichardo B. Abnormal immunological response to Mycobacterium tuberculosis antigens in a patient with chronic myelocytic leukemia and active tuberculosis. P R Health Sci J. 1998 Dec; 17(4):345-52.

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