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Hassan Ashktorab

TitleProfessor
Faculty RankProfessor
InstitutionHoward University
DepartmentMedicine
AddressCancer Center Rm320
Howard University
2041 Georgia Ave
Washington DC 20060
Phone2028066121
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    Other Positions
    TitleProfessor
    InstitutionHoward University
    DepartmentMedicine


    Collapse Biography 
    Collapse awards and honors
    2015Jingsue University visiting professor, Jingsue University

    Collapse Overview 
    Collapse overview
    Gastroenterology cancer research group at HU Cancer Center

    Dr. Hassan Ashktorab is Professor in the Departments of Medicine. He serves, or has served as the member of gastrointestinal working group in the Howard University Cancer Center, executive member of The Howard University Cancer Center, Adjunct Professor at The Department of Genetics and Human Genetics and the Director of Microarray facility at Howard University and former Chair of College of Medicine Research committee. He is a member of the Editorial boards of PLoS One, Digestive Diseases and Science, World Journal of Gastroenterology and Gouvaresh and former Editorial Board member of Gut. He has been awarded several NIH grants including RO3, RO1 and DOD grants. He received the HU-COM Outstanding Researcher Award in 2011. He has been a member of different NIH study sections since 2005. Dr. Ashktorab’s group focus is on epigenetics, genetics and epidemiology of gastrointestinal cancers especially colorectal cancer.

    Gastroenterology Research:
    Gastroenterology laboratory is investigating the molecular mechanisms governing cellular proliferation, including epigenetic and genetic influence during oncogenic transformation and tumorigenesis. The long term goals include the identification and characterization of epigenetic factors such as DNA methylation, miRNA and histone modifications that play a central and direct role in the initiation and/or progression of human cancers, specifically gastric and colon cancer. This includes research on chromatin modification through methylation or acetylation of genes/histones that may play critical roles in the regulation of transcription of many genes, leading to alteration of cell function and cell cycle. In addition, the detection of DNA methylation biomarkers for both early detection and prognosis is part of our interests using Next Generation Sequencing (NGS). We have recently detected several epigenetic biomarkers that are hypermethylated significantly in tumors from African Americans compared to Caucasians. Dr. Ashktorab’s translational/clinical research focuses on the African American population, investigating genomic instability and gene silencing in patients with adenoma and colorectal cancer. This is a critical step for the understanding of the onset of cancer progression in African Americans with the goal of tackling this health disparity in this population.

    NGS is revolutionizing medicine and health care approaches. As it becomes cheaper and more accessible, more in-depth personalized genomic information will be available that dictates more appropriate and individualized approaches for both detection and treatment.
    Dr. Ashktorab’s NGS research recently identified novel mutations in African Americans with colorectal cancer which were highlighted in the Journal Cancer. His group is working toward biomarkers identification in early to late colorectal carcinogenesis. One of the genes that is an early marker in colorectal carcinogenesis is APC. This gene is part of WNT pathway and his group found novel mutations in African Americans with colorectal cancer which is highlighted in Cancer and PNAS 2015.
    The identification of these biomarkers will help in the detection, prognostic and treatment of the patients. The NGS research is followed by targeted exome sequencing for gene panels in detect colorectal cancer specifically in African Americans.
    Much of the sporadic colorectal cancer’s underlying genetic mutations (driver genes) are unknown in patients from specific ethnic groups such as African Americans. We also reported the identification of distinct novel variants from adenoma and CRC patients in mismatch repair (MMR) genes MHS3 and MSH6, and in PIK3CA.

    A new line of research was recently developed with Dr. Brim in the context of the role that the gut microbiota might play in the initiation and progression of colon neoplasia. Dr. Brim is a faculty at the Department of Pathology. Several publications have pointed to potential roles of specific bacteria in triggering genetic and epigenetic events such as those described in colon carcinogenesis. The primary goal of this line of research is to define specific bacteria that associate with higher risk of neoplasia. This will likely offer the opportunity to intervene at the gut microbiota’s level to reduce the risk of colon carcinogenesis.

    We are also collaborating with Dr. Laiyemo, a gastroenterologist and Dr. Nouraie Faculty at the College of medicine, on several epidemiological studies that seek to assess factors at play in the adherence to colonoscopy and treatment in minority patients.

    Along with our genetic, epigenetic, microbiomic and epidemiological studies that target colorectal cancer in African Americans, we are also investigating such a disease in other minorities such as Hispanics. We are also investigating other gastrointestinal diseases through several ongoing epidemiological studies such as hepatic fibrosis, hepatocellular carcinoma, gastroesophageal reflux disease, esophageal cancer and anal cancer in African Americans among several other projects.

    Please visit PubMed for the recent publications.


    Collapse Research 
    Collapse research activities and funding
    R03DK056664     (ASHKTORAB, HASSAN)Sep 30, 2001 - Nov 30, 2004
    NIH
    Mechanisms of Growth Inhibition by Helicobacter Pylor
    Role: Principal Investigator
    R01CA102681     (ASHKTORAB, HASSAN)Sep 1, 2003 - Aug 31, 2010
    NIH
    METHYLATION PROFILING AND RISK OF COLORECTAL CANCER
    Role: Principal Investigator
    R01CA258519     (ASHKTORAB, HASSAN ;CARETHERS, JOHN M)Aug 1, 2021 - Jul 31, 2026
    NIH
    Inactivation of MSH3 in Colorectal Cancer and Race
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lu J, Bang H, Kim SM, Cho SJ, Ashktorab H, Smoot DT, Zheng CH, Ryeom SW, Yoon SS, Yoon C, Lee JH. Retraction Note: Lymphatic metastasis-related TBL1XR1 enhances stemness and metastasis in gastric cancer stem-like cells by activating ERK1/2-SOX2 signaling. Oncogene. 2024 Feb 20. PMID: 38378920.
      Citations:    Fields:    
    2. Igder S, Zamani M, Fakher S, Siri M, Ashktorab H, Azarpira N, Mokarram P. Circulating Nucleic Acids in Colorectal Cancer: Diagnostic and Prognostic Value. Dis Markers. 2024; 2024:9943412. PMID: 38380073.
      Citations:    Fields:    Translation:HumansCells
    3. Rashid M, Rashid R, Gadewal N, Carethers JM, Koi M, Brim H, Ashktorab H. High-throughput sequencing and in-silico analysis confirm pathogenicity of novel MSH3 variants in African American colorectal cancer. Neoplasia. 2024 Mar; 49:100970. PMID: 38281411.
      Citations:    Fields:    Translation:HumansCells
    4. Zeng J, Xie C, Huang Z, Cho CH, Chan H, Li Q, Ashktorab H, Smoot DT, Wong SH, Yu J, Gong W, Liang C, Xu H, Chen H, Liu X, Wu JCY, Ip M, Gin T, Zhang L, Chan MTV, Hu W, Wu WKK. LOX-1 acts as an N6-methyladenosine-regulated receptor for Helicobacter pylori by binding to the bacterial catalase. Nat Commun. 2024 Jan 22; 15(1):669. PMID: 38253620.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Kim JY, Min YJ, Lee M-H, An YR, Ashktorab H, Smoot DT, Kwon SW, Lee SK. Ceramide promotes lytic reactivation of Epstein-Barr virus in gastric carcinoma. J Virol. 2024 Feb 20; 98(2):e0177623. PMID: 38197630.
      Citations:    Fields:    Translation:HumansCells
    6. Khan M, Hearn K, Parry C, Rasid M, Brim H, Ashktorab H, Kwabi-Addo B. Mechanism of Antitumor Effects of Saffron in Human Prostate Cancer Cells. Nutrients. 2023 Dec 28; 16(1). PMID: 38201944.
      Citations:    Fields:    Translation:HumansAnimals
    7. Ashktorab H, Challa SR, Singh G, Nanduri S, Ibrahim M, Martirosyan Z, Whitsell P, Chirumamilla LG, Shayegh N, Watson K, Smith T, Ogwo V, Kolawole O, Littleton M, Morrison N, Nair V, Byer D, Dawodu DO, Lexima P, Rashid M, Deverapalli M, Atluri SM, Nezamloo A, Nasrin F, Kim RJ, Sherif Z, Oskrochi G, Carethers JM, Brim H. Gastrointestinal Manifestations and Their Association with Neurologic and Sleep Problems in Long COVID-19 Minority Patients: A Prospective Follow-Up Study. Dig Dis Sci. 2024 Feb; 69(2):562-569. PMID: 38135813.
      Citations:    Fields:    Translation:HumansCells
    8. Huang KK, Ma H, Chong RHH, Uchihara T, Lian BSX, Zhu F, Sheng T, Srivastava S, Tay ST, Sundar R, Tan ALK, Ong X, Lee M, Ho SWT, Lesluyes T, Ashktorab H, Smoot D, Van Loo P, Chua JS, Ramnarayanan K, Lau LHS, Gotoda T, Kim HS, Ang TL, Khor C, Lee JWJ, Tsao SKK, Yang WL, Teh M, Chung H, So JBY, Yeoh KG, Tan P. Spatiotemporal genomic profiling of intestinal metaplasia reveals clonal dynamics of gastric cancer progression. Cancer Cell. 2023 Dec 11; 41(12):2019-2037.e8. PMID: 37890493.
      Citations:    Fields:    Translation:Humans
    9. Ishikawa A, Yasumatsu R, Fukui T, Kido A, Katsuya N, Sentani K, Kuraoka K, Oue N, Suzuki T, Oka S, Kotachi T, Tanabe K, Ohdan H, Ashktorab H, Smoot D, Yasui W. Kinesin family member B18 is related to gastric mucin phenotype and contributes to gastric cancer progression by regulating epithelial-mesenchymal transition. Oncology. 2023 Oct 09. PMID: 37812924.
      Citations: 1     Fields:    
    10. Vernia F, Ashktorab H, Cesaro N, Monaco S, Faenza S, Sgamma E, Viscido A, Latella G. COVID-19 and Gastrointestinal Tract: From Pathophysiology to Clinical Manifestations. Medicina (Kaunas). 2023 Sep 24; 59(10). PMID: 37893427.
      Citations:    Fields:    Translation:HumansCells
    11. Sherif ZA, Deverapalli M, Challa SR, Martirosyan Z, Whitesell P, Pizuorno AM, Naqvi Z, Tulloch IK, Oskrochi G, Brim H, Ashktorab H. Potential long-term neurological and gastrointestinal effects of COVID-19: A review of adult cohorts. World J Methodol. 2023 Sep 20; 13(4):323-336. PMID: 37771866.
      Citations:    
    12. Papadaki V, Erpapazoglou Z, Kokkori M, Rogalska ME, Potiri M, Birladeanu A, Tsakiri EN, Ashktorab H, Smoot DT, Papanikolopoulou K, Samiotaki M, Kafasla P. IQGAP1 mediates the communication between the nucleus and the mitochondria via NDUFS4 alternative splicing. NAR Cancer. 2023 Sep; 5(3):zcad046. PMID: 37636315.
      Citations:    
    13. Ashktorab H, Oskrochi G, Challa SR, Chirumamilla LG, Ahangarzadeh F, Jones-Wonni B, Shayegh N, Rashid M, Naqvi Z, Ekpe E, Sabyasachi S, Zenebe A, Brim H. Correction to: High Prevalence of Diabetes Among Hospitalized COVID-19 Minority Patients: Data from a Single Tertiary Hospital. J Racial Ethn Health Disparities. 2023 Aug 08. PMID: 37552425.
      Citations:    Fields:    
    14. Ashktorab H, Geramfard S, Rashid M, Rashid R, Mynedi SM, Nouraie M, Nezamloo A, Brim H. Exploring the Incidence and Associated Risk Factors of Barrett's Esophagus in African Americans: A Retrospective Study. Rep Glob Health Res. 2023; 6(3). PMID: 38044960.
      Citations:    
    15. Ashktorab H, Oskrochi G, Challa SR, Chirumamilla LG, Ahangarzadeh F, Jones-Wonni B, Shayegh N, Rashid M, Naqvi Z, Ekpe E, Sabyasachi S, Zenebe A, Brim H. High Prevalence of Diabetes Among Hospitalized COVID-19 Minority Patients: Data from a Single Tertiary Hospital. J Racial Ethn Health Disparities. 2023 Jul 27. PMID: 37500830.
      Citations:    Fields:    
    16. Singh G, Brim H, Haileselassie Y, Varma S, Habtezion A, Rashid M, Sinha SR, Ashktorab H. Microbiomic and Metabolomic Analyses Unveil the Protective Effect of Saffron in a Mouse Colitis Model. Curr Issues Mol Biol. 2023 Jun 30; 45(7):5558-5574. PMID: 37504267.
      Citations: 1     Fields:    
    17. Ashktorab H, Brim H. Editorial to the Special Issue 'Nutritional Intervention in Digestive Diseases in the Era of Nutraceuticals, Nutrigenomics and Microbiomics'. Nutrients. 2023 Jun 29; 15(13). PMID: 37447291.
      Citations:    Fields:    
    18. Horwitz LI, Thaweethai T, Brosnahan SB, Cicek MS, Fitzgerald ML, Goldman JD, Hess R, Hodder SL, Jacoby VL, Jordan MR, Krishnan JA, Laiyemo AO, Metz TD, Nichols L, Patzer RE, Sekar A, Singer NG, Stiles LE, Taylor BS, Ahmed S, Algren HA, Anglin K, Aponte-Soto L, Ashktorab H, Bassett IV, Bedi B, Bhadelia N, Bime C, Bind MC, Black LJ, Blomkalns AL, Brim H, Castro M, Chan J, Charney AW, Chen BK, Chen LQ, Chen P, Chestek D, Chibnik LB, Chow DC, Chu HY, Clifton RG, Collins S, Costantine MM, Cribbs SK, Deeks SG, Dickinson JD, Donohue SE, Durstenfeld MS, Emery IF, Erlandson KM, Facelli JC, Farah-Abraham R, Finn AV, Fischer MS, Flaherman VJ, Fleurimont J, Fonseca V, Gallagher EJ, Gander JC, Gennaro ML, Gibson KS, Go M, Goodman SN, Granger JP, Greenway FL, Hafner JW, Han JE, Harkins MS, Hauser KSP, Heath JR, Hernandez CR, Ho O, Hoffman MK, Hoover SE, Horowitz CR, Hsu H, Hsue PY, Hughes BL, Jagannathan P, James JA, John J, Jolley S, Judd SE, Juskowich JJ, Kanjilal DG, Karlson EW, Katz SD, Kelly JD, Kelly SW, Kim AY, Kirwan JP, Knox KS, Kumar A, Lamendola-Essel MF, Lanca M, Lee-Lannotti JK, Lefebvre RC, Levy BD, Lin JY, Logarbo BP, Logue JK, Longo MT, Luciano CA, Lutrick K, Malakooti SK, Mallett G, Maranga G, Marathe JG, Marconi VC, Marshall GD, Martin CF, Martin JN, May HT, McComsey GA, McDonald D, Mendez-Figueroa H, Miele L, Mittleman MA, Mohandas S, Mouchati C, Mullington JM, Nadkarni GN, Nahin ER, Neuman RB, Newman LT, Nguyen A, Nikolich JZ, Ofotokun I, Ogbogu PU, Palatnik A, Palomares KTS, Parimon T, Parry S, Parthasarathy S, Patterson TF, Pearman A, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Porterfield JZ, Quigley JG, Quinn DK, Raissy H, Rebello CJ, Reddy UM, Reece R, Reeder HT, Rischard FP, Rosas JM, Rosen CJ, Rouphael NG, Rouse DJ, Ruff AM, Saint Jean C, Sandoval GJ, Santana JL, Schlater SM, Sciurba FC, Selvaggi C, Seshadri S, Sesso HD, Shah DP, Shemesh E, Sherif ZA, Shinnick DJ, Simhan HN, Singh U, Sowles A, Subbian V, Sun J, Suthar MS, Teunis LJ, Thorp JM, Ticotsky A, Tita ATN, Tragus R, Tuttle KR, Urdaneta AE, Utz PJ, VanWagoner TM, Vasey A, Vernon SD, Vidal C, Walker T, Ward HD, Warren DE, Weeks RM, Weiner SJ, Weyer JC, Wheeler JL, Whiteheart SW, Wiley Z, Williams NJ, Wisnivesky JP, Wood JC, Yee LM, Young NM, Zisis SN, Foulkes AS. Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design. PLoS One. 2023; 18(6):e0286297. PMID: 37352211.
      Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
    19. Thaweethai T, Jolley SE, Karlson EW, Levitan EB, Levy B, McComsey GA, McCorkell L, Nadkarni GN, Parthasarathy S, Singh U, Walker TA, Selvaggi CA, Shinnick DJ, Schulte CCM, Atchley-Challenner R, Alba GA, Alicic R, Altman N, Anglin K, Argueta U, Ashktorab H, Baslet G, Bassett IV, Bateman L, Bedi B, Bhattacharyya S, Bind MA, Blomkalns AL, Bonilla H, Bush PA, Castro M, Chan J, Charney AW, Chen P, Chibnik LB, Chu HY, Clifton RG, Costantine MM, Cribbs SK, Davila Nieves SI, Deeks SG, Duven A, Emery IF, Erdmann N, Erlandson KM, Ernst KC, Farah-Abraham R, Farner CE, Feuerriegel EM, Fleurimont J, Fonseca V, Franko N, Gainer V, Gander JC, Gardner EM, Geng LN, Gibson KS, Go M, Goldman JD, Grebe H, Greenway FL, Habli M, Hafner J, Han JE, Hanson KA, Heath J, Hernandez C, Hess R, Hodder SL, Hoffman MK, Hoover SE, Huang B, Hughes BL, Jagannathan P, John J, Jordan MR, Katz SD, Kaufman ES, Kelly JD, Kelly SW, Kemp MM, Kirwan JP, Klein JD, Knox KS, Krishnan JA, Kumar A, Laiyemo AO, Lambert AA, Lanca M, Lee-Iannotti JK, Logarbo BP, Longo MT, Luciano CA, Lutrick K, Maley JH, Marathe JG, Marconi V, Marshall GD, Martin CF, Matusov Y, Mehari A, Mendez-Figueroa H, Mermelstein R, Metz TD, Morse R, Mosier J, Mouchati C, Mullington J, Murphy SN, Neuman RB, Nikolich JZ, Ofotokun I, Ojemakinde E, Palatnik A, Palomares K, Parimon T, Parry S, Patterson JE, Patterson TF, Patzer RE, Peluso MJ, Pemu P, Pettker CM, Plunkett BA, Pogreba-Brown K, Poppas A, Quigley JG, Reddy U, Reece R, Reeder H, Reeves WB, Reiman EM, Rischard F, Rosand J, Rouse DJ, Ruff A, Saade G, Sandoval GJ, Schlater SM, Shepherd F, Sherif ZA, Simhan H, Singer NG, Skupski DW, Sowles A, Sparks JA, Sukhera FI, Taylor BS, Teunis L, Thomas RJ, Thorp JM, Thuluvath P, Ticotsky A, Tita AT, Tuttle KR, Urdaneta AE, Valdivieso D, VanWagoner TM, Vasey A, Verduzco-Gutierrez M, Wallace ZS, Ward HD, Warren DE, Weiner SJ, Welch S, Whiteheart SW, Wiley Z, Wisnivesky JP, Yee LM, Zisis S, Horwitz LI, Foulkes AS. Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection. JAMA. 2023 06 13; 329(22):1934-1946. PMID: 37278994.
      Citations: 70     Fields:    Translation:HumansCells
    20. Xu C, Huang KK, Law JH, Chua JS, Sheng T, Flores NM, Pizzi MP, Okabe A, Tan ALK, Zhu F, Kumar V, Lu X, Benitez AM, Lian BSX, Ma H, Ho SWT, Ramnarayanan K, Anene-Nzelu CG, Razavi-Mohseni M, Abdul Ghani SAB, Tay ST, Ong X, Lee MH, Guo YA, Ashktorab H, Smoot D, Li S, Skanderup AJ, Beer MA, Foo RSY, Wong JSH, Sanghvi K, Yong WP, Sundar R, Kaneda A, Prabhakar S, Mazur PK, Ajani JA, Yeoh KG, So JB, Tan P. Comprehensive molecular phenotyping of ARID1A-deficient gastric cancer reveals pervasive epigenomic reprogramming and therapeutic opportunities. Gut. 2023 09; 72(9):1651-1663. PMID: 36918265.
      Citations: 1     Fields:    Translation:Humans
    21. Nargund AM, Xu C, Mandoli A, Okabe A, Chen GB, Huang KK, Sheng T, Yao X, Teo JMN, Sundar R, Kok YJ, See YX, Xing M, Li Z, Yong CH, Anand A, Bin Adam Isa ZF, Poon LF, Ng MSW, Koh JYP, Ooi WF, Tay ST, Ong X, Tan ALK, Smoot DT, Ashktorab H, Grabsch HI, Fullwood MJ, Teh BT, Bi X, Kaneda A, Li S, Tan P. Correction: Chromatin Rewiring by Mismatch Repair Protein MSH2 Alters Cell Adhesion Pathways and Sensitivity to BET Inhibition in Gastric Cancer. Cancer Res. 2023 Mar 02; 83(5):804. PMID: 36861360.
      Citations:    Fields:    
    22. Yuan Y, Zhang X, Du K, Zhu X, Chang S, Chen Y, Xu Y, Sun J, Luo X, Deng S, Qin Y, Feng X, Wei Y, Fan X, Liu Z, Zheng B, Ashktorab H, Smoot D, Li S, Xie X, Jin Z, Peng Y. Circ_CEA promotes the interaction between the p53 and cyclin-dependent kinases 1 as a scaffold to inhibit the apoptosis of gastric cancer. Cell Death Dis. 2022 Sep 27; 13(9):827. PMID: 36167685.
      Citations: 5     Fields:    Translation:HumansCells
    23. Routledge D, Rogers S, Ono Y, Brunt L, Meniel V, Tornillo G, Ashktorab H, Phesse TJ, Scholpp S. The scaffolding protein flot2 promotes cytoneme-based transport of wnt3 in gastric cancer. Elife. 2022 08 30; 11. PMID: 36040316.
      Citations: 3     Fields:    Translation:AnimalsCells
    24. Ashktorab H, Pizuorno A, Adeleye F, Laiyemo A, Dalivand MM, Aduli F, Sherif ZA, Oskrochi G, Angesom K, Oppong-Twene P, Challa SR, Okorie N, Moon ES, Romos E, Jones-Wonni B, Kone AM, Rankine S, Thrift C, Scholes D, Ekwunazu C, Banson A, Mitchell B, Maskalo G, Ross J, Curtis J, Kim R, Gilliard C, Ahuja G, Mathew J, Gavin W, Kara A, Hache-Marliere M, Palaiodimos L, Mani VR, Kalabin A, Gayam VR, Garlapati PR, Miller J, Chirumamilla LG, Jackson F, Carethers JM, Kamangar F, Brim H. Correction: Symptomatic, clinical and?biomarker associations for?mortality in?hospitalized COVID-19 patients enriched for?African Americans. BMC Infect Dis. 2022 Aug 29; 22(1):712. PMID: 36038841.
      Citations: 1     Fields:    
    25. Rashid M, Brim H, Ashktorab H. Saffron, Its Active Components, and Their Association with DNA and Histone Modification: A Narrative Review of Current Knowledge. Nutrients. 2022 Aug 12; 14(16). PMID: 36014823.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    26. Hu F, Peng Y, Chang S, Luo X, Yuan Y, Zhu X, Xu Y, Du K, Chen Y, Deng S, Yu F, Feng X, Fan X, Ashktorab H, Smoot D, Meltzer SJ, Li S, Wei Y, Zhang X, Jin Z. Vimentin binds to a novel tumor suppressor protein, GSPT1-238aa, encoded by circGSPT1 with a selective encoding priority to halt autophagy in gastric carcinoma. Cancer Lett. 2022 10 01; 545:215826. PMID: 35839920.
      Citations: 6     Fields:    Translation:HumansCells
    27. Ahmad S, Ashktorab H, Brim H, Housseau F. Inflammation, microbiome and colorectal cancer disparity in African-Americans: Are there bugs in the genetics? World J Gastroenterol. 2022 Jul 07; 28(25):2782-2801. PMID: 35978869.
      Citations: 1     Fields:    Translation:Humans
    28. Ashktorab H, Pizuorno A, Adeleye F, Laiyemo A, Dalivand MM, Aduli F, Sherif ZA, Oskrochi G, Angesom K, Oppong-Twene P, Challa SR, Okorie N, Moon ES, Romos E, Jones-Wonni B, Kone AM, Rankine S, Thrift C, Scholes D, Ekwunazu C, Banson A, Mitchell B, Maskalo G, Ross J, Curtis J, Kim R, Gilliard C, Ahuja G, Mathew J, Gavin W, Kara A, Hache-Marliere M, Palaiodimos L, Mani VR, Kalabin A, Gayam VR, Garlapati PR, Miller J, Chirumamilla LG, Jackson F, Carethers JM, Kamangar F, Brim H. Symptomatic, clinical and biomarker associations for mortality in hospitalized COVID-19 patients enriched for African Americans. BMC Infect Dis. 2022 Jun 17; 22(1):552. PMID: 35715729.
      Citations: 6     Fields:    Translation:HumansCells
    29. Challa SR, Oskrochi G, Chirumamilla LG, Shayegh N, Brim H, Ashktorab H. Predictors of Mortality in Hospitalized African American Covid-19 Cancer Patients. Res Sq. 2022 Mar 22. PMID: 35350203.
      Citations:    
    30. Ashktorab H, Russo T, Oskrochi G, Latella G, Massironi S, Luca M, Chirumamilla LG, Laiyemo AO, Brim H. Clinical and Endoscopic Outcomes in Coronavirus Disease-2019 Patients With Gastrointestinal Bleeding. Gastro Hep Adv. 2022; 1(4):487-499. PMID: 35287301.
      Citations:    
    31. Ashktorab H, Brim H. Colorectal cancer subtyping. Nat Rev Cancer. 2022 02; 22(2):68-69. PMID: 34880443.
      Citations: 5     Fields:    Translation:Humans
    32. Longo S, Altobelli E, Castellini C, Vernia F, Valvano M, Magistroni M, Mancusi A, Viscido A, Ashktorab H, Latella G. Non-steroidal anti-inflammatory drugs and acetylsalicylic acid increase the risk of complications of diverticular disease: a meta-analysis of case-control and cohort studies. Int J Colorectal Dis. 2022 Mar; 37(3):521-529. PMID: 35094111.
      Citations: 2     Fields:    Translation:Humans
    33. Yoon JH, Eun JW, Ashktorab H, Smoot DT, Kim JK, Nam SW, Park WS. Depletion of NK6 Homeobox 3 (NKX6.3) causes gastric carcinogenesis through copy number alterations by inducing impairment of DNA replication and repair regulation. Oncogenesis. 2021 Dec 10; 10(12):85. PMID: 34893582.
      Citations:    
    34. Peng Y, Xu Y, Zhang X, Deng S, Yuan Y, Luo X, Hossain MT, Zhu X, Du K, Hu F, Chen Y, Chang S, Feng X, Fan X, Ashktorab H, Smoot D, Meltzer SJ, Hou G, Wei Y, Li S, Qin Y, Jin Z. A novel protein AXIN1-295aa encoded by circAXIN1 activates the Wnt/?-catenin signaling pathway to promote gastric cancer progression. Mol Cancer. 2021 12 04; 20(1):158. PMID: 34863211.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    35. Mokarram P, Niknam M, Sadeghdoust M, Aligolighasemabadi F, Siri M, Dastghaib S, Brim H, Ashktorab H. PIWI interacting RNAs perspectives: a new avenues in future cancer investigations. Bioengineered. 2021 12; 12(2):10401-10419. PMID: 34723746.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    36. Brim H, Ashktorab H. Integrating microbiomics in cancer management. Nat Rev Cancer. 2021 11; 21(11):684-685. PMID: 34316056.
      Citations: 3     Fields:    Translation:Humans
    37. Ashktorab H, Folake A, Pizuorno A, Oskrochi G, Oppong-Twene P, Tamanna N, Mehdipour Dalivand M, Umeh LN, Moon ES, Kone AM, Banson A, Federman C, Ramos E, Awoyemi EO, Wonni BJ, Otto E, Maskalo G, Velez AO, Rankine S, Thrift C, Ekwunazu C, Scholes D, Chirumamilla LG, Ibrahim ME, Mitchell B, Ross J, Curtis J, Kim R, Gilliard C, Mathew J, Laiyemo A, Kibreab A, Lee E, Sherif Z, Shokrani B, Aduli F, Brim H. COVID-19 among African Americans and Hispanics: Does gastrointestinal symptoms impact the outcome? World J Clin Cases. 2021 Oct 06; 9(28):8374-8387. PMID: 34754847.
      Citations:    
    38. Pizuorno A, Brim H, Ashktorab H. Gastrointestinal manifestations and SARS-CoV-2 infection. Curr Opin Pharmacol. 2021 12; 61:114-119. PMID: 34688995.
      Citations: 4     Fields:    Translation:HumansCells
    39. Lu J, Cao LL, Xu Y, Huang XY, Cho SJ, Ashktorab H, Smoot DT, Li P, Zheng CH, Kim JW, Ryeom SW, Yoon SS, Yoon C, Huang CM. WITHDRAWN: FOXC1 modulates stem-like cell properties and chemoresistance through hedgehog and EMT signaling in gastric adenocarcinoma. Mol Ther. 2021 09 15. PMID: 34534693.
      Citations: 3     Fields:    
    40. Russo T, Pizuorno A, Oskrochi G, Latella G, Massironi S, Schettino M, Aghemo A, Pugliese N, Brim H, Ashktorab H. Gastrointestinal Manifestations, Clinical Characteristics and Outcomes of COVID-19 in Adult and Pediatric Patients. SOJ Microbiol Infect Dis. 2021; 8(1). PMID: 35611315.
      Citations:    
    41. Chirumamilla LG, Brim H, Pizuorno A, Oskrochi G, Ashktorab H. Covid-19 and Gastrointestinal Manifestations in Indian Patients: A Meta-Analysis. SOJ Microbiol Infect Dis. 2021; 8(1):1-7. PMID: 36034468.
      Citations:    
    42. Ashktorab H, Pizuorno A, Fierro NA, Villagrana EDC, Solis MEH, Cardenas G, Alvarez DZ, Oskrochi G, Adeleye F, Dalivand MM, Laiyemo AO, Aduli F, Sherif ZA, Brim H. A Comprehensive Meta-Analysis of COVID-19 in Latin America. SOJ Microbiol Infect Dis. 2021; 8(1):1-11. PMID: 35937158.
      Citations:    
    43. Najar MA, Aravind A, Dagamajalu S, Sidransky D, Ashktorab H, Smoot DT, Gowda H, Prasad TSK, Modi PK, Chatterjee A. Hyperactivation of MEK/ERK pathway by Ca2+ /calmodulin-dependent protein kinase kinase 2?promotes cellular proliferation by activating cyclin-dependent kinases?and minichromosome maintenance protein?in gastric cancer cells. Mol Carcinog. 2021 11; 60(11):769-783. PMID: 34437731.
      Citations: 8     Fields:    Translation:HumansCells
    44. Brim H, Taylor J, Abbas M, Vilmenay K, Daremipouran M, Varma S, Lee E, Pace B, Song-Naba WL, Gupta K, Nekhai S, O'Neil P, Ashktorab H. The gut microbiome in sickle cell disease: Characterization and potential implications. PLoS One. 2021; 16(8):e0255956. PMID: 34432825.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    45. Singh G, Haileselassie Y, Ji AR, Maecker HT, Sinha SR, Brim H, Habtezion A, Ashktorab H. Protective Effect of Saffron in Mouse Colitis Models Through Immune Modulation. Dig Dis Sci. 2022 07; 67(7):2922-2935. PMID: 34275090.
      Citations: 7     Fields:    Translation:HumansAnimals
    46. Mokarram P, Dalivand MM, Pizuorno A, Aligolighasemabadi F, Sadeghdoust M, Sadeghdoust E, Aduli F, Oskrochi G, Brim H, Ashktorab H. Clinical characteristics, gastrointestinal manifestations and outcomes of COVID-19 patients in Iran; does the location matters? World J Clin Cases. 2021 Jun 26; 9(18):4654-4667. PMID: 34222432.
      Citations:    
    47. Amin A, Farrukh A, Murali C, Soleimani A, Praz F, Graziani G, Brim H, Ashktorab H. Saffron and Its Major Ingredients' Effect on Colon Cancer Cells with Mismatch Repair Deficiency and Microsatellite Instability. Molecules. 2021 Jun 24; 26(13). PMID: 34202689.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    48. Pizuorno A, Fierro NA, Copado-Villagrana ED, Herrera-Sol?s ME, Oskrochi G, Brim H, Ashktorab H. COVID-19 and gastrointestinal symptoms in Mexico, a systematic review: does location matter? BMC Infect Dis. 2021 Jun 11; 21(1):555. PMID: 34116647.
      Citations: 2     Fields:    Translation:HumansCells
    49. Banskota S, Brim H, Kwon YH, Singh G, Sinha SR, Wang H, Khan WI, Ashktorab H. Saffron Pre-Treatment Promotes Reduction in Tissue Inflammatory Profiles and Alters Microbiome Composition in Experimental Colitis Mice. Molecules. 2021 Jun 02; 26(11). PMID: 34199466.
      Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
    50. Ashktorab H, Brim H. Blood-Based Liquid Biopsies: A Noninvasive and Cost-Effective Tool for Improved Risk Assessment and Identification of Lymph Node Metastasis in Patients With Submucosal T1 Colorectal Cancer. Gastroenterology. 2021 07; 161(1):29-31. PMID: 33895167.
      Citations: 2     Fields:    Translation:Humans
    51. Peng Y, Qin Y, Zhang X, Deng S, Yuan Y, Feng X, Chen W, Hu F, Gao Y, He J, Cheng Y, Wei Y, Fan X, Ashktorab H, Smoot D, Li S, Meltzer SJ, Zhuang S, Tang N, Jin Z. MiRNA-20b/SUFU/Wnt axis accelerates gastric cancer cell proliferation, migration and EMT. Heliyon. 2021 Apr; 7(4):e06695. PMID: 33912703.
      Citations:    
    52. Peng Y, Zhang X, Lin H, Deng S, Qin Y, He J, Hu F, Zhu X, Feng X, Wang J, Wei Y, Fan X, Lin H, Ashktorab H, Smoot D, Lv Y, Li S, Meltzer SJ, Jin Z. Dual activation of Hedgehog and Wnt/?-catenin signaling pathway caused by downregulation of SUFU targeted by miRNA-150 in human gastric cancer. Aging (Albany NY). 2021 04 12; 13(7):10749-10769. PMID: 33848981.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    53. Ashktorab H, Pizuorno A, Aduli F, Laiyemo AO, Oskrochi G, Brim H. Elevated Liver Enzymes, Ferritin, C-reactive Protein, D-dimer, and Age Are Predictive Markers of Outcomes Among African American and Hispanic Patients With Coronavirus Disease 2019. Gastroenterology. 2021 07; 161(1):345-349. PMID: 33811923.
      Citations: 4     Fields:    Translation:Humans
    54. Sherif ZA, Nouraie SM, Lee E, Aduli F, Brim H, Ashktorab H. Trends in the Incidence of Hepatocellular Carcinoma in Washington DC: A Single Institutional Cohort Study (1959-2013). J Natl Med Assoc. 2021 Aug; 113(4):396-404. PMID: 33648723.
      Citations:    Fields:    Translation:Humans
    55. Dixit P, Kokate SB, Poirah I, Chakraborty D, Smoot DT, Ashktorab H, Rout N, Singh SP, Bhattacharyya A. Helicobacter pylori-induced gastric cancer is orchestrated by MRCK?-mediated Siah2 phosphorylation. J Biomed Sci. 2021 Feb 03; 28(1):12. PMID: 33536006.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    56. Viscido A, Ciccone F, Vernia F, Gabrieli D, Capannolo A, Stefanelli G, Necozione S, Valerii G, Ashktorab H, Latella G. Association of Colonic Diverticula with Colorectal Adenomas and Cancer. Medicina (Kaunas). 2021 Jan 25; 57(2). PMID: 33504050.
      Citations:    Fields:    Translation:Humans
    57. Ashktorab H, Pizuomo A, Gonz?lez NAF, Villagrana EDC, Herrera-Sol?s ME, Cardenas G, Zavala-Alvarez D, Oskrochi G, Awoyemi E, Adeleye F, Dalivand MM, Laiyemo AO, Lee EE, Aduli F, Sherif ZA, Brim H. A Comprehensive Analysis of COVID-19 Impact in Latin America. Res Sq. 2021 Jan 08. PMID: 33442675.
      Citations:    
    58. Lu J, Bang H, Kim SM, Cho SJ, Ashktorab H, Smoot DT, Zheng CH, Ryeom SW, Yoon SS, Yoon C, Lee JH. Lymphatic metastasis-related TBL1XR1 enhances stemness and metastasis in gastric cancer stem-like cells by activating ERK1/2-SOX2 signaling. Oncogene. 2021 02; 40(5):922-936. PMID: 33288885.
      Citations: 7     Fields:    Translation:HumansCells
    59. Ashktorab H, Pizuorno A, Oskroch G, Fierro NA, Sherif ZA, Brim H. COVID-19 in Latin America: Symptoms, Morbidities, and Gastrointestinal Manifestations. Gastroenterology. 2021 02; 160(3):938-940. PMID: 33160964.
      Citations: 11     Fields:    Translation:Humans
    60. Zhang X, Peng Y, Yuan Y, Gao Y, Hu F, Wang J, Zhu X, Feng X, Cheng Y, Wei Y, Fan X, Xie Y, Lv Y, Ashktorab H, Smoot D, Li S, Meltzer SJ, Hou G, Jin Z. Histone methyltransferase SET8 is regulated by miR-192/215 and induces oncogene-induced senescence via p53-dependent DNA damage in human gastric carcinoma cells. Cell Death Dis. 2020 10 30; 11(10):937. PMID: 33127874.
      Citations: 11     Fields:    Translation:HumansAnimals
    61. Brim H, Mirabello L, Bass S, Ford DH, Carethers JM, Ashktorab H. Association of Human Papillomavirus Genotype 16 Lineages With Anal Cancer Histologies Among African Americans. Gastroenterology. 2021 02; 160(3):922-924. PMID: 33075347.
      Citations: 2     Fields:    Translation:HumansCells
    62. Chawla K, Kibreab A, Scott V, Lee EL, Aduli F, Brim H, Ashktorab H, Howell CD, Laiyemo AO. Association of Patients' Perception of Quality of Healthcare Received and Colorectal Cancer Screening Uptake: An Analysis of 2 National Surveys in the USA. Med Princ Pract. 2021; 30(4):331-338. PMID: 33049736.
      Citations: 2     Fields:    Translation:Humans
    63. Peng Y, Zhang X, Lin H, Deng S, Qin Y, Yuan Y, Feng X, Wang J, Chen W, Hu F, Yan R, Zhao Y, Cheng Y, Wei Y, Fan X, Ashktorab H, Smoot D, Li S, Meltzer SJ, Jin Z. SUFU mediates EMT and Wnt/?-catenin signaling pathway activation promoted by miRNA-324-5p in human gastric cancer. Cell Cycle. 2020 10; 19(20):2720-2733. PMID: 33017570.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    64. Shokrani B, Brim H, Hydari T, Afsari A, Lee E, Nouraie M, Sherif Z, Ashktorab H. Analysis of ?-catenin association with obesity in African Americans with premalignant and malignant colorectal lesions. BMC Gastroenterol. 2020 Aug 18; 20(1):274. PMID: 32811441.
      Citations: 1     Fields:    Translation:HumansCells
    65. G?ll? N, Kobelt D, Brim H, Rahman S, Timm L, Smith J, Soleimani A, Di Marco S, Bisti S, Ashktorab H, Stein U. Saffron Crudes and Compounds Restrict MACC1-Dependent Cell Proliferation and Migration of Colorectal Cancer Cells. Cells. 2020 08 03; 9(8). PMID: 32756469.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    66. Stefanelli G, Viscido A, Valvano M, Vernia F, Frieri G, Ashktorab H, Latella G. Is mesalazine treatment effective in the prevention of diverticulitis? A review. Eur Rev Med Pharmacol Sci. 2020 08; 24(15):8164-8176. PMID: 32767345.
      Citations: 1     Fields:    Translation:Humans
    67. Ni Z, Min Y, Han C, Yuan T, Lu W, Ashktorab H, Smoot DT, Wu Q, Wu J, Zeng W, Shi Y. TGR5-HNF4a axis contributes to bile acid-induced gastric intestinal metaplasia markers expression. Cell Death Discov. 2020; 6:56. PMID: 32655894.
      Citations:    
    68. Ashktorab H, Brim H, Hassan S, Nouraie M, Gebreselassie A, Laiyemo AO, Kibreab A, Aduli F, Latella G, Brant SR, Sherif Z, Habtezion A. Inflammatory polyps occur more frequently in inflammatory bowel disease than other colitis patients. BMC Gastroenterol. 2020 Jun 05; 20(1):170. PMID: 32503428.
      Citations: 7     Fields:    Translation:Humans
    69. Ashktorab H, Washington K, Zarnogi S, Shakoori A, Varma S, Lee E, Shokrani B, Laiyemo A, Brim H. Determination of distinctive hypomethylated genes in African American colorectal neoplastic lesions. Therap Adv Gastroenterol. 2020; 13:1756284820905482. PMID: 32547637.
      Citations:    
    70. Aziz N, Hong YH, Jo M, Kim JK, Kim KH, Ashktorab H, Smoot DT, Hur H, Yoo BC, Cho AJY. Molecular Signatures of JMJD10/MINA53 in Gastric Cancer. Cancers (Basel). 2020 May 02; 12(5). PMID: 32370161.
      Citations:    
    71. Lee JY, Kim N, Choi YJ, Park JH, Ashktorab H, Smoot DT, Lee DH. Expression of Tight Junction Proteins According to Functional Dyspepsia Subtype and Sex. J Neurogastroenterol Motil. 2020 Apr 30; 26(2):248-258. PMID: 32235032.
      Citations:    
    72. Erfani M, Hosseini SV, Mokhtari M, Zamani M, Tahmasebi K, Alizadeh Naini M, Taghavi A, Carethers JM, Koi M, Brim H, Mokarram P, Ashktorab H. Altered ARID1A expression in colorectal cancer. BMC Cancer. 2020 Apr 25; 20(1):350. PMID: 32334542.
      Citations: 15     Fields:    Translation:HumansCells
    73. Laiyemo AO, Idowu KA, Burnside C, Williams CD, Jack M, Mekasha G, Ashktorab H, Brim H, Lee EL, Sanderson AK, Kibreab A, Kwagyan J. Comparison of patterns of laxative ingestion to improve bowel preparation for colonoscopy: a pilot randomized clinical trial. Endosc Int Open. 2020 May; 8(5):E617-E622. PMID: 32355879.
      Citations:    
    74. Yoon JH, Ashktorab H, Smoot DT, Nam SW, Hur H, Park WS. Uptake and tumor-suppressive pathways of exosome-associated GKN1 protein in gastric epithelial cells. Gastric Cancer. 2020 09; 23(5):848-862. PMID: 32291710.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    75. Sherif ZA, Nouraie M, Begum R, Afsari A, Shokrani B, Lee E, Laiyemo AO, Brim H, Ashktorab H. Factors influencing treatment outcome in hepatitis C virus minority patients at an inner-city hospital: A STROBE-complaint article. Medicine (Baltimore). 2020 Apr; 99(14):e19505. PMID: 32243366.
      Citations: 1     Fields:    Translation:Humans
    76. Deng S, Zhang X, Qin Y, Chen W, Fan H, Feng X, Wang J, Yan R, Zhao Y, Cheng Y, Wei Y, Fan X, Ashktorab H, Smoot D, Meltzer SJ, Li S, Li K, Peng Y, Jin Z. miRNA-192 and -215 activate Wnt/?-catenin signaling pathway in gastric cancer via APC. J Cell Physiol. 2020 09; 235(9):6218-6229. PMID: 32091625.
      Citations: 18     Fields:    Translation:HumansCells
    77. Amnekar RV, Khan SA, Rashid M, Khade B, Thorat R, Gera P, Shrikhande SV, Smoot DT, Ashktorab H, Gupta S. Histone deacetylase inhibitor pre-treatment enhances the efficacy of DNA-interacting chemotherapeutic drugs in gastric cancer. World J Gastroenterol. 2020 Feb 14; 26(6):598-613. PMID: 32103870.
      Citations: 7     Fields:    Translation:HumansCells
    78. Kim BR, Jeong YA, Kim DY, Kim JL, Jeong S, Na YJ, Yun HK, Park SH, Jo MJ, Ashktorab H, Smoot DT, Lee DH, Oh SC. Genipin increases oxaliplatin-induced cell death through autophagy in gastric cancer. J Cancer. 2020; 11(2):460-467. PMID: 31897241.
      Citations:    
    79. Ashktorab H, Sherif Z, Tarjoman T, Azam S, Lee E, Shokrani B, Okereke I, Soleimani A, Carethers JM, Laiyemo AO, Aduli F, Nouraie M, Habtezion A, Brim H. Elevated Risk for Sessile Serrated Polyps in African Americans with Endometrial Polyps. Dig Dis Sci. 2020 09; 65(9):2686-2690. PMID: 31832971.
      Citations: 3     Fields:    Translation:Humans
    80. Jeong S, Jo MJ, Yun HK, Kim DY, Kim BR, Kim JL, Park SH, Na YJ, Jeong YA, Kim BG, Ashktorab H, Smoot DT, Heo JY, Han J, Il Lee S, Do Kim H, Kim DH, Oh SC, Lee DH. Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer. Cell Death Dis. 2019 11 07; 10(11):846. PMID: 31699976.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    81. Igder S, Mohammadiasl J, Azadpour S, Mansouri E, Ashktorab H, Mokarram P. KRAS mutation and abnormal expression of Cripto-1 as two potential candidate biomarkers for detection of colorectal cancer development. J Cell Biochem. 2020 04; 121(4):2901-2908. PMID: 31692030.
      Citations: 1     Fields:    Translation:Humans
    82. Laiyemo AO, Kwagyan J, Williams CD, Rogers J, Kibreab A, Jack MA, Lee EE, Brim H, Ashktorab H, Howell CD, Smoot DT, Platz EA. Using Patients' Social Network to Improve Compliance to Outpatient Screening Colonoscopy Appointments Among Blacks: A Randomized Clinical Trial. Am J Gastroenterol. 2019 10; 114(10):1671-1677. PMID: 31478919.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    83. Choi SI, Yoon C, Park MR, Lee D, Kook MC, Lin JX, Kang JH, Ashktorab H, Smoot DT, Yoon SS, Cho SJ. CDX1 Expression Induced by CagA-Expressing Helicobacter pylori Promotes Gastric Tumorigenesis. Mol Cancer Res. 2019 11; 17(11):2169-2183. PMID: 31416838.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    84. Jo MJ, Jeong S, Yun HK, Kim DY, Kim BR, Kim JL, Na YJ, Park SH, Jeong YA, Kim BG, Ashktorab H, Smoot DT, Heo JY, Han J, Lee DH, Oh SC. Genipin induces mitochondrial dysfunction and apoptosis via downregulation of Stat3/mcl-1 pathway in gastric cancer. BMC Cancer. 2019 Jul 27; 19(1):739. PMID: 31351462.
      Citations: 18     Fields:    Translation:HumansCells
    85. Nouraie M, Ashktorab H, Atefi N, Azam S, Tarjoman T, Lee E, Shokrani B, Afsari A, Soleimani A, Laiyemo AO, Singh S, Brim H. Can the rate and location of sessile serrated polyps be part of colorectal Cancer disparity in African Americans? BMC Gastroenterol. 2019 May 24; 19(1):77. PMID: 31126232.
      Citations: 3     Fields:    Translation:Humans
    86. Xu C, Ooi WF, Qamra A, Tan J, Chua BY, Ho SWT, Das K, Adam Isa ZF, Li Z, Yao X, Yan T, Xing M, Huang KK, Lin JS, Nandi T, Tay ST, Lee MH, Tan ALK, Ong X, Ashktorab H, Smoot D, Li S, Ng SC, Teh BT, Tan P. HNF4a pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer. Gut. 2020 02; 69(2):231-242. PMID: 31068366.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    87. Ashktorab H, Soleimani A, Singh G, Amin A, Tabtabaei S, Latella G, Stein U, Akhondzadeh S, Solanki N, Gondr?-Lewis MC, Habtezion A, Brim H. Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases. Nutrients. 2019 04 26; 11(5). PMID: 31027364.
      Citations: 41     Fields:    Translation:HumansAnimals
    88. Ashktorab H, Delker D, Kanth P, Goel A, Carethers JM, Brim H. Molecular Characterization of Sessile Serrated Adenoma/Polyps From a Large African American Cohort. Gastroenterology. 2019 08; 157(2):572-574. PMID: 31004568.
      Citations: 8     Fields:    Translation:Humans
    89. Ashktorab H, Azimi H, Varma S, Lee EL, Laiyemo AO, Nickerson ML, Brim H. Driver genes exome sequencing reveals distinct variants in African Americans with colorectal neoplasia. Oncotarget. 2019 Apr 05; 10(27):2607-2624. PMID: 31080553.
      Citations: 5     Fields:    
    90. Wang Z, Ma K, Pitts S, Cheng Y, Liu X, Ke X, Kovaka S, Ashktorab H, Smoot DT, Schatz M, Wang Z, Meltzer SJ. Novel circular RNA circNF1 acts as a molecular sponge, promoting gastric cancer by absorbing miR-16. Endocr Relat Cancer. 2019 03; 26(3):265-277. PMID: 30576282.
      Citations: 30     Fields:    Translation:HumansCells
    91. Yoon JH, Lee YS, Kim O, Ashktorab H, Smoot DT, Nam SW, Park WS. NKX6.3 protects against gastric mucosal atrophy by downregulating ?-amyloid production. World J Gastroenterol. 2019 Jan 21; 25(3):330-345. PMID: 30686901.
      Citations: 2     Fields:    Translation:HumansCells
    92. Hu W, Zhang L, Li MX, Shen J, Liu XD, Xiao ZG, Wu DL, Ho IHT, Wu JCY, Cheung CKY, Zhang YC, Lau AHY, Ashktorab H, Smoot DT, Fang EF, Chan MTV, Gin T, Gong W, Wu WKK, Cho CH. Vitamin D3 activates the autolysosomal degradation function against Helicobacter pylori through the PDIA3 receptor in gastric epithelial cells. Autophagy. 2019 04; 15(4):707-725. PMID: 30612517.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    93. Kang MH, Jeong GS, Smoot DT, Ashktorab H, Hwang CM, Kim BS, Kim HS, Park YY. Correction: Verteporfin inhibits gastric cancer cell growth by suppressing adhesion molecule FAT1. Oncotarget. 2018 12 14; 9(98):37268. PMID: 30647858.
      Citations: 2     Fields:    
    94. Yoon JH, Kim O, Eun JW, Choi SS, Ashktorab H, Smoot DT, Nam SW, Park WS. Multiple genetic mutations caused by NKX6.3 depletion contribute to gastric tumorigenesis. Sci Rep. 2018 12 04; 8(1):17609. PMID: 30514953.
      Citations: 4     Fields:    Translation:HumansAnimals
    95. Bhattacharya S, Reddy D, Jani V, Gadewal N, Shah S, Reddy R, Bose K, Sonavane U, Joshi R, Smoot D, Ashktorab H, Gupta S. Correction to: Histone isoform H2A1H promotes attainment of distinct physiological states by altering chromatin dynamics. Epigenetics Chromatin. 2018 11 16; 11(1):67. PMID: 30446005.
      Citations:    Fields:    
    96. Ashktorab H, Rahi H, Nouraie M, Shokrani B, Lee E, Haydari T, Laiyemo AO, Siegel P, Brim H. GPNMB methylation: a new marker of potentially carcinogenic colon lesions. BMC Cancer. 2018 Nov 06; 18(1):1068. PMID: 30400781.
      Citations: 4     Fields:    Translation:HumansCells
    97. Peng Y, Zhang X, Lin H, Deng S, Huang Y, Qin Y, Feng X, Yan R, Zhao Y, Cheng Y, Wei Y, Wang J, Chen W, Fan X, Ashktorab H, Smoot D, Meltzer SJ, Li S, Zhang Z, Jin Z. Inhibition of miR-194 suppresses the Wnt/?-catenin signalling pathway in gastric cancer. Oncol Rep. 2018 Dec; 40(6):3323-3334. PMID: 30542715.
      Citations: 9     Fields:    Translation:HumansCells
    98. Liu X, Abraham JM, Cheng Y, Wang Z, Wang Z, Zhang G, Ashktorab H, Smoot DT, Cole RN, Boronina TN, DeVine LR, Talbot CC, Liu Z, Meltzer SJ. Synthetic Circular RNA Functions as a miR-21 Sponge to Suppress Gastric Carcinoma Cell Proliferation. Mol Ther Nucleic Acids. 2018 Dec 07; 13:312-321. PMID: 30326427.
      Citations:    
    99. Shahnazi A, Badurdeen D, Laiyemo AO, Nouraie M, Brim H, Wessly P, Geramfard S, Afsari A, Page N, Ashktorab H. Obesity and Pancreatic Cysts in African American Patients. Cureus. 2018 Aug 20; 10(8):e3160. PMID: 30357033.
      Citations:    
    100. Cho SJ, Yoon C, Lee JH, Chang KK, Lin JX, Kim YH, Kook MC, Aksoy BA, Park DJ, Ashktorab H, Smoot DT, Schultz N, Yoon SS. KMT2C Mutations in Diffuse-Type Gastric Adenocarcinoma Promote Epithelial-to-Mesenchymal Transition. Clin Cancer Res. 2018 12 15; 24(24):6556-6569. PMID: 30108106.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    101. Kokate SB, Dixit P, Poirah I, Roy AD, Chakraborty D, Rout N, Singh SP, Ashktorab H, Smoot DT, Bhattacharyya A. Testin and filamin-C downregulation by acetylated Siah2 increases invasiveness of Helicobacter pylori-infected gastric cancer cells. Int J Biochem Cell Biol. 2018 10; 103:14-24. PMID: 30063986.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    102. Brim H, Shahnazi A, Nouraie M, Badurdeen D, Laiyemo AO, Haidary T, Afsari A, Ashktorab H. Gastrointestinal Lesions in African American Patients With Iron Deficiency Anemia. Clin Med Insights Gastroenterol. 2018; 11:1179552218778627. PMID: 29795991.
      Citations:    
    103. Yoon JH, Ham IH, Kim O, Ashktorab H, Smoot DT, Nam SW, Lee JY, Hur H, Park WS. Gastrokine 1 protein is a potential theragnostic target for gastric cancer. Gastric Cancer. 2018 11; 21(6):956-967. PMID: 29704153.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    104. Sahin D, Taflan SO, Yartas G, Ashktorab H, Smoot DT. Screening and Identification of Peptides Specifically Targeted to Gastric Cancer Cells from a Phage Display Peptide Library Asian Pac J Cancer Prev. 2018 Apr 25; 19(4):927-932. PMID: 29693344.
      Citations: 2     Fields:    Translation:HumansCells
    105. Choi W, Kim J, Park J, Lee DH, Hwang D, Kim JH, Ashktorab H, Smoot D, Kim SY, Choi C, Koh GY, Lim DS. YAP/TAZ Initiates Gastric Tumorigenesis via Upregulation of MYC. Cancer Res. 2018 06 15; 78(12):3306-3320. PMID: 29669762.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    106. Ashktorab H, Soleimani A, Nichols A, Sodhi K, Laiyemo AO, Nunlee-Bland G, Nouraie SM, Brim H. Adiponectin, Leptin, IGF-1, and Tumor Necrosis Factor Alpha As Potential Serum Biomarkers for Non-Invasive Diagnosis of Colorectal Adenoma in African Americans. Front Endocrinol (Lausanne). 2018; 9:77. PMID: 29593647.
      Citations: 5     Fields:    
    107. Zhang L, Hu W, Cho CH, Chan FK, Yu J, Fitzgerald JR, Cheung CK, Xiao ZG, Shen J, Li LF, Li MX, Wu JC, Ling TK, Chan JY, Ko H, Tse G, Ng SC, Yu S, Wang MH, Gin T, Ashktorab H, Smoot DT, Wong SH, Chan MT, Wu WK. Reduced lysosomal clearance of autophagosomes promotes survival and colonization of Helicobacter pylori. J Pathol. 2018 04; 244(4):432-444. PMID: 29327342.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    108. Kavousipour S, Mokarram P, Gargari SLM, Mostafavi-Pour Z, Barazesh M, Ramezani A, Ashktorab H, Mohammadi S, Ghavami S. A Comparison Between Cell, Protein and Peptide-Based Approaches for Selection of Nanobodies Against CD44 from a Synthetic Library. Protein Pept Lett. 2018; 25(6):580-588. PMID: 29848261.
      Citations: 3     Fields:    Translation:HumansCells
    109. Mimura K, Teh JL, Okayama H, Shiraishi K, Kua LF, Koh V, Smoot DT, Ashktorab H, Oike T, Suzuki Y, Fazreen Z, Asuncion BR, Shabbir A, Yong WP, So J, Soong R, Kono K. PD-L1 expression is mainly regulated by interferon gamma associated with JAK-STAT pathway in gastric cancer. Cancer Sci. 2018 Jan; 109(1):43-53. PMID: 29034543.
      Citations: 162     Fields:    Translation:HumansCells
    110. Brim H, Yooseph S, Lee E, Sherif ZA, Abbas M, Laiyemo AO, Varma S, Torralba M, Dowd SE, Nelson KE, Pathmasiri W, Sumner S, de Vos W, Liang Q, Yu J, Zoetendal E, Ashktorab H. A Microbiomic Analysis in African Americans with Colonic Lesions Reveals Streptococcus sp.VT162 as a Marker of Neoplastic Transformation. Genes (Basel). 2017 11 09; 8(11). PMID: 29120399.
      Citations: 12     Fields:    
    111. Kang MH, Jeong GS, Smoot DT, Ashktorab H, Hwang CM, Kim BS, Kim HS, Park YY. Verteporfin inhibits gastric cancer cell growth by suppressing adhesion molecule FAT1. Oncotarget. 2017 Nov 17; 8(58):98887-98897. PMID: 29228735.
      Citations: 14     Fields:    
    112. Bhattacharya S, Reddy D, Jani V, Gadewal N, Shah S, Reddy R, Bose K, Sonavane U, Joshi R, Smoot D, Ashktorab H, Gupta S. Histone isoform H2A1H promotes attainment of distinct physiological states by altering chromatin dynamics. Epigenetics Chromatin. 2017 10 18; 10(1):48. PMID: 29047414.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    113. Ashktorab H, Azimi H, Varma S, Tavakoli P, Nickerson ML, Brim H. Distinctive DNA mismatch repair and APC rare variants in African Americans with colorectal neoplasia. Oncotarget. 2017 Nov 21; 8(59):99966-99977. PMID: 29245953.
      Citations: 4     Fields:    
    114. Ashktorab H, Kupfer SS, Brim H, Carethers JM. Racial Disparity in Gastrointestinal Cancer Risk. Gastroenterology. 2017 10; 153(4):910-923. PMID: 28807841.
      Citations: 113     Fields:    Translation:Humans
    115. Afsari A, Lee E, Shokrani B, Boortalary T, Sherif ZA, Nouraie M, Laiyemo AO, Alkhalloufi K, Brim H, Ashktorab H. Clinical and Pathological Risk Factors Associated with Liver Fibrosis and Steatosis in African-Americans with Chronic Hepatitis C. Dig Dis Sci. 2017 08; 62(8):2159-2165. PMID: 28612194.
      Citations: 3     Fields:    Translation:HumansCells
    116. Qamra A, Xing M, Padmanabhan N, Kwok JJT, Zhang S, Xu C, Leong YS, Lee Lim AP, Tang Q, Ooi WF, Suling Lin J, Nandi T, Yao X, Ong X, Lee M, Tay ST, Keng ATL, Gondo Santoso E, Ng CCY, Ng A, Jusakul A, Smoot D, Ashktorab H, Rha SY, Yeoh KG, Peng Yong W, Chow PKH, Chan WH, Ong HS, Soo KC, Kim KM, Wong WK, Rozen SG, Teh BT, Kappei D, Lee J, Connolly J, Tan P. Epigenomic Promoter Alterations Amplify Gene Isoform and Immunogenic Diversity in Gastric Adenocarcinoma. Cancer Discov. 2017 06; 7(6):630-651. PMID: 28320776.
      Citations: 29     Fields:    Translation:HumansCells
    117. Sanabria-Salas MC, Hern?ndez-Su?rez G, Uma?a-P?rez A, Rawlik K, Tenesa A, Serrano-L?pez ML, S?nchez de G?mez M, Rojas MP, Bravo LE, Albis R, Plata JL, Green H, Borgovan T, Li L, Majumdar S, Garai J, Lee E, Ashktorab H, Brim H, Li L, Margolin D, Fejerman L, Zabaleta J. IL1B-CGTC haplotype is associated with colorectal cancer in admixed individuals with increased African ancestry. Sci Rep. 2017 02 03; 7:41920. PMID: 28157220.
      Citations: 7     Fields:    Translation:HumansCells
    118. Kim O, Yoon JH, Choi WS, Ashktorab H, Smoot DT, Nam SW, Lee JY, Park WS. Heterodimeric interaction between GKN2 and TFF1 entails synergistic antiproliferative and pro-apoptotic effects on gastric cancer cells. Gastric Cancer. 2017 Sep; 20(5):772-783. PMID: 28150071.
      Citations: 10     Fields:    Translation:HumansCells
    119. Ashktorab H, Mokarram P, Azimi H, Olumi H, Varma S, Nickerson ML, Brim H. Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer. Oncotarget. 2017 Jan 31; 8(5):7852-7866. PMID: 28002797.
      Citations: 17     Fields:    Translation:Cells
    120. Rath S, Das L, Kokate SB, Ghosh N, Dixit P, Rout N, Singh SP, Chattopadhyay S, Ashktorab H, Smoot DT, Swamy MM, Kundu TK, Crowe SE, Bhattacharyya A. Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness. Int J Biochem Cell Biol. 2017 01; 82:28-40. PMID: 27890795.
      Citations: 4     Fields:    Translation:HumansCells
    121. Liang Q, Chiu J, Chen Y, Huang Y, Higashimori A, Fang J, Brim H, Ashktorab H, Ng SC, Ng SSM, Zheng S, Chan FKL, Sung JJY, Yu J. Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer. Clin Cancer Res. 2017 04 15; 23(8):2061-2070. PMID: 27697996.
      Citations: 145     Fields:    Translation:Humans
    122. Brim H, Ashktorab H. Genomics of Colorectal Cancer in African Americans. Next Gener Seq Appl. 2016 Sep; 3(2). PMID: 27917406.
      Citations:    
    123. Ashktorab H, Shakoori A, Zarnogi S, Sun X, Varma S, Lee E, Shokrani B, Laiyemo AO, Washington K, Brim H. Reduced Representation Bisulfite Sequencing Determination of Distinctive DNA Hypermethylated Genes in the Progression to Colon Cancer in African Americans. Gastroenterol Res Pract. 2016; 2016:2102674. PMID: 27688749.
      Citations:    
    124. Ashktorab H, Etaati F, Rezaeean F, Nouraie M, Paydar M, Namin HH, Sanderson A, Begum R, Alkhalloufi K, Brim H, Laiyemo AO. Can optical diagnosis of small colon polyps be accurate? Comparing standard scope without narrow banding to high definition scope with narrow banding. World J Gastroenterol. 2016 Jul 28; 22(28):6539-46. PMID: 27605888.
      Citations: 2     Fields:    Translation:Humans
    125. Ashktorab H, Hermann P, Nouraie M, Shokrani B, Lee E, Haidary T, Brim H, Stein U. Increased MACC1 levels in tissues and blood identify colon adenoma patients at high risk. J Transl Med. 2016 07 20; 14(1):215. PMID: 27439755.
      Citations: 8     Fields:    Translation:Humans
    126. Ashktorab H, Vilmenay K, Brim H, Laiyemo AO, Kibreab A, Nouraie M. Colorectal Cancer in Young African Americans: Is It Time to Revisit Guidelines and Prevention? Dig Dis Sci. 2016 10; 61(10):3026-3030. PMID: 27278956.
      Citations: 28     Fields:    Translation:Humans
    127. Ashktorab H, Ahuja S, Kannan L, Llor X, Ellis NA, Xicola RM, Laiyemo AO, Carethers JM, Brim H, Nouraie M. A meta-analysis of MSI frequency and race in colorectal cancer. Oncotarget. 2016 Apr 23; 7(23):34546-57. PMID: 27120810.
      Citations: 55     Fields:    Translation:Humans
    128. Shahnazi A, Sanderson AK, Laiyemo AO, Nouraie M, Haidary T, Brim H, Geramfard S, Afsari A, Ashktorab H. Diabetes Mellitus and Pancreatic Cysts in African Americans. Pancreas. 2016 Apr; 45(4):e14-5. PMID: 26954497.
      Citations:    Fields:    Translation:Humans
    129. Sherif ZA, Saeed A, Ghavimi S, Nouraie SM, Laiyemo AO, Brim H, Ashktorab H. Global Epidemiology of Nonalcoholic Fatty Liver Disease and Perspectives on US Minority Populations. Dig Dis Sci. 2016 May; 61(5):1214-25. PMID: 27038448.
      Citations: 78     Fields:    Translation:Humans
    130. Ashktorab H, Azimi H, Nickerson ML, Bass S, Varma S, Brim H. Targeted Exome Sequencing Outcome Variations of Colorectal Tumors within and across Two Sequencing Platforms. Next Gener Seq Appl. 2016 Jun; 3(1). PMID: 27547838.
      Citations:    
    131. Ashktorab H, Ogundipe T, Brim H, Shahnazi A, Laiyemo AO, Lee E, Shokrani B, Nouraie M. Lymph nodes' evaluation in relation to colorectal cancer staging among African Americans. BMC Cancer. 2015 Dec 16; 15:976. PMID: 26673446.
      Citations: 2     Fields:    Translation:Humans
    132. Ashktorab H, Laiyemo AO, Lee E, Cruz-Correa M, Ghuman A, Nouraie M, Brim H. Prevalence and features of colorectal lesions among Hispanics: A hospital-based study. World J Gastroenterol. 2015 Dec 14; 21(46):13095-100. PMID: 26673447.
      Citations: 5     Fields:    Translation:Humans
    133. Laiyemo AO, Thompson N, Williams CD, Idowu KA, Bull-Henry K, Sherif ZA, Lee EL, Brim H, Ashktorab H, Platz EA, Smoot DT. Race and colorectal cancer screening compliance among persons with a family history of cancer. World J Gastrointest Endosc. 2015 Dec 10; 7(18):1300-5. PMID: 26672497.
      Citations:    
    134. Nayani R, Ashktorab H, Brim H, Laiyemo AO. Genetic Basis for Colorectal Cancer Disparities. Curr Colorectal Cancer Rep. 2015 Dec 01; 11(6):408-413. PMID: 26997937.
      Citations:    
    135. Nouraie M, Kansal V, Belfonte C, Ghazvini M, Haidari T, Shahnazi A, Brim H, Soliman EZ, Ashktorab H. Atrial Fibrillation and Colonic Neoplasia in African Americans. PLoS One. 2015; 10(8):e0135609. PMID: 26317627.
      Citations: 2     Fields:    Translation:Humans
    136. Laiyemo AO, Burnside C, Laiyemo MA, Kwagyan J, Williams CD, Idowu KA, Ashktorab H, Kibreab A, Scott VF, Sanderson AK. Beverage intake preference and bowel preparation laxative taste preference for colonoscopy. World J Gastrointest Pharmacol Ther. 2015 Aug 06; 6(3):84-8. PMID: 26261736.
      Citations:    
    137. Ashktorab H, Panchal H, Shokrani B, Paydar M, Sanderson A, Lee EL, Begum R, Haidary T, Laiyemo AO, McDonald-Pinkett S, Brim H, Nouraie M. Association between Diverticular Disease and Pre-Neoplastic Colorectal Lesions in an Urban African-American Population. Digestion. 2015; 92(2):60-5. PMID: 26183208.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    138. Ashktorab H, Varma S, Brim H. Next-generation sequencing in African Americans with colorectal cancer. Proc Natl Acad Sci U S A. 2015 Jun 02; 112(22):E2852. PMID: 25941412.
      Citations: 7     Fields:    Translation:Humans
    139. Kim O, Yoon JH, Choi WS, Ashktorab H, Smoot DT, Nam SW, Lee JY, Park WS. Gastrokine 1 inhibits gastrin-induced cell proliferation. Gastric Cancer. 2016 Apr; 19(2):381-391. PMID: 25752269.
      Citations: 7     Fields:    Translation:HumansCells
    140. Ashktorab H, Brim H. DNA Methylation and Colorectal Cancer. Curr Colorectal Cancer Rep. 2014 Dec 01; 10(4):425-430. PMID: 25580099.
      Citations:    
    141. Ashktorab H, Daremipouran M, Devaney J, Varma S, Rahi H, Lee E, Shokrani B, Schwartz R, Nickerson ML, Brim H. Identification of novel mutations by exome sequencing in African American colorectal cancer patients. Cancer. 2015 Jan 01; 121(1):34-42. PMID: 25250560.
      Citations: 27     Fields:    Translation:HumansCells
    142. Yoon JH, Seo HS, Choi SS, Chae HS, Choi WS, Kim O, Ashktorab H, Smoot DT, Nam SW, Lee JY, Park WS. Gastrokine 1 inhibits the carcinogenic potentials of Helicobacter pylori CagA. Carcinogenesis. 2014 Nov; 35(11):2619-29. PMID: 25239641.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    143. Laiyemo AO, Williams CD, Burnside C, Moghadam S, Sanasi-Bhola KD, Kwagyan J, Brim H, Ashktorab H, Scott VF, Smoot DT. Factors associated with attendance to scheduled outpatient endoscopy. Postgrad Med J. 2014 Oct; 90(1068):571-5. PMID: 25180285.
      Citations: 8     Fields:    Translation:Humans
    144. Hor YT, Voon DC, Koo JK, Wang H, Lau WM, Ashktorab H, Chan SL, Ito Y. A role for RUNX3 in inflammation-induced expression of IL23A in gastric epithelial cells. Cell Rep. 2014 Jul 10; 8(1):50-8. PMID: 25008775.
      Citations: 16     Fields:    Translation:HumansCells
    145. Lee KS, Park JL, Lee K, Richardson LE, Johnson BH, Lee HS, Lee JS, Kim SB, Kwon OH, Song KS, Kim YS, Ashktorab H, Smoot DT, Jeon SH, Kim SY, Lee YS. nc886, a non-coding RNA of anti-proliferative role, is suppressed by CpG DNA methylation in human gastric cancer. Oncotarget. 2014 Jun 15; 5(11):3944-55. PMID: 25003254.
      Citations: 45     Fields:    Translation:HumansCells
    146. Kim O, Yoon JH, Choi WS, Ashktorab H, Smoot DT, Nam SW, Lee JY, Park WS. GKN2 contributes to the homeostasis of gastric mucosa by inhibiting GKN1 activity. J Cell Physiol. 2014 Jun; 229(6):762-71. PMID: 24151046.
      Citations: 19     Fields:    Translation:HumansCells
    147. Shim JH, Yoon JH, Choi SS, Ashktorab H, Smoot DT, Song KY, Nam SW, Lee JY, Park CH, Park WS. The effect of Helicobacter pylori CagA on the HER-2 copy number and expression in gastric cancer. Gene. 2014 Aug 10; 546(2):288-96. PMID: 24879917.
      Citations: 8     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    148. Brim H, Zahaf M, Laiyemo AO, Nouraie M, P?rez-P?rez GI, Smoot DT, Lee E, Razjouyan H, Ashktorab H. Gastric Helicobacter pylori infection associates with an increased risk of colorectal polyps in African Americans. BMC Cancer. 2014 Apr 28; 14:296. PMID: 24774100.
      Citations: 20     Fields:    Translation:HumansCells
    149. Ashktorab H, Paydar M, Yazdi S, Namin HH, Sanderson A, Begum R, Semati M, Etaati F, Lee E, Brim H, Zenebe A, Nunlee-Bland G, Laiyemo AO, Nouraie M. BMI and the risk of colorectal adenoma in African-Americans. Obesity (Silver Spring). 2014 May; 22(5):1387-91. PMID: 24519988.
      Citations: 14     Fields:    Translation:Humans
    150. Brim H, Abu-Asab MS, Nouraie M, Salazar J, Deleo J, Razjouyan H, Mokarram P, Schaffer AA, Naghibhossaini F, Ashktorab H. An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors. PLoS One. 2014; 9(1):e82185. PMID: 24475022.
      Citations: 21     Fields:    Translation:HumansCells
    151. Shin JY, Kim YI, Cho SJ, Lee MK, Kook MC, Lee JH, Lee SS, Ashktorab H, Smoot DT, Ryu KW, Kim YW, Choi IJ. MicroRNA 135a suppresses lymph node metastasis through down-regulation of ROCK1 in early gastric cancer. PLoS One. 2014; 9(1):e85205. PMID: 24465504.
      Citations: 41     Fields:    Translation:HumansCells
    152. Ashktorab H, Daremipouran M, Goel A, Varma S, Leavitt R, Sun X, Brim H. DNA methylome profiling identifies novel methylated genes in African American patients with colorectal neoplasia. Epigenetics. 2014 Apr; 9(4):503-12. PMID: 24441198.
      Citations: 44     Fields:    Translation:HumansCells
    153. Brim H, Yooseph S, Zoetendal EG, Lee E, Torralbo M, Laiyemo AO, Shokrani B, Nelson K, Ashktorab H. Microbiome analysis of stool samples from African Americans with colon polyps. PLoS One. 2013; 8(12):e81352. PMID: 24376500.
      Citations: 31     Fields:    Translation:HumansCells
    154. Fatemi M, Paul TA, Brodeur GM, Shokrani B, Brim H, Ashktorab H. Epigenetic silencing of CHD5, a novel tumor-suppressor gene, occurs in early colorectal cancer stages. Cancer. 2014 Jan 15; 120(2):172-80. PMID: 24243398.
      Citations: 35     Fields:    Translation:HumansCells
    155. Ashktorab H, Paydar M, Namin HH, Sanderson A, Begum R, Brim H, Panchal H, Lee E, Kibreab A, Nouraie M, Laiyemo AO. Prevalence of colorectal neoplasia among young African Americans and Hispanic Americans. Dig Dis Sci. 2014 Feb; 59(2):446-50. PMID: 24193352.
      Citations: 14     Fields:    Translation:Humans
    156. Yoon JH, Cho ML, Choi YJ, Back JY, Park MK, Lee SW, Choi BJ, Ashktorab H, Smoot DT, Nam SW, Lee JY, Park WS. Gastrokine 1 regulates NF-?B signaling pathway and cytokine expression in gastric cancers. J Cell Biochem. 2013 Aug; 114(8):1800-9. PMID: 23444260.
      Citations: 14     Fields:    Translation:HumansCellsCTClinical Trials
    157. Yoon JH, Choi YJ, Choi WS, Ashktorab H, Smoot DT, Nam SW, Lee JY, Park WS. GKN1-miR-185-DNMT1 axis suppresses gastric carcinogenesis through regulation of epigenetic alteration and cell cycle. Clin Cancer Res. 2013 Sep 01; 19(17):4599-610. PMID: 23846337.
      Citations: 34     Fields:    Translation:HumansCells
    158. Ashktorab H, Rahi H, Wansley D, Varma S, Shokrani B, Lee E, Daremipouran M, Laiyemo A, Goel A, Carethers JM, Brim H. Toward a comprehensive and systematic methylome signature in colorectal cancers. Epigenetics. 2013 Aug; 8(8):807-15. PMID: 23975090.
      Citations: 35     Fields:    Translation:HumansCells
    159. Ashktorab H, Hassanzadeh Namin H, Taylor T, Williams C, Brim H, Mellman T, Shokrani B, Holt CL, Laiyemo AO, Nouraie M. Role of life events in the presence of colon polyps among African Americans. BMC Gastroenterol. 2013 Jun 12; 13:101. PMID: 23758671.
      Citations: 4     Fields:    Translation:Humans
    160. Marimuthu A, Subbannayya Y, Sahasrabuddhe NA, Balakrishnan L, Syed N, Sekhar NR, Katte TV, Pinto SM, Srikanth SM, Kumar P, Pawar H, Kashyap MK, Maharudraiah J, Ashktorab H, Smoot DT, Ramaswamy G, Kumar RV, Cheng Y, Meltzer SJ, Roa JC, Chaerkady R, Prasad TS, Harsha HC, Chatterjee A, Pandey A. SILAC-based quantitative proteomic analysis of gastric cancer secretome. Proteomics Clin Appl. 2013 Jun; 7(5-6):355-66. PMID: 23161554.
      Citations: 28     Fields:    Translation:HumansCells
    161. Errami Y, Brim H, Oumouna-Benachour K, Oumouna M, Naura AS, Kim H, Ju J, Davis CJ, Kim JG, Ashktorab H, Fallon K, Xu M, Zhang J, Del Valle L, Boulares AH. ICAD deficiency in human colon cancer and predisposition to colon tumorigenesis: linkage to apoptosis resistance and genomic instability. PLoS One. 2013; 8(2):e57871. PMID: 23451280.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    162. Laiyemo AO, Doubeni C, Brim H, Ashktorab H, Schoen RE, Gupta S, Charabaty A, Lanza E, Smoot DT, Platz E, Cross AJ. Short- and long-term risk of colorectal adenoma recurrence among whites and blacks. Gastrointest Endosc. 2013 Mar; 77(3):447-54. PMID: 23337636.
      Citations: 15     Fields:    Translation:Humans
    163. Mitchell BD, Lee WJ, Tolea MI, Shields K, Ashktorab Z, Magder LS, Ryan KA, Pollin TI, McArdle PF, Shuldiner AR, Sch?ffer AA. Living the good life? Mortality and hospital utilization patterns in the Old Order Amish. PLoS One. 2012; 7(12):e51560. PMID: 23284714.
      Citations: 15     Fields:    Translation:Humans
    164. Yang Y, Toy W, Choong LY, Hou P, Ashktorab H, Smoot DT, Yeoh KG, Lim YP. Discovery of SLC3A2 cell membrane protein as a potential gastric cancer biomarker: implications in molecular imaging. J Proteome Res. 2012 Dec 07; 11(12):5736-47. PMID: 23116296.
      Citations: 26     Fields:    Translation:HumansCells
    165. Ashktorab H, Entezari O, Nouraie M, Dowlati E, Frederick W, Woods A, Lee E, Brim H, Smoot DT, Ghadyari F, Kamangar F, Razjouyan H. Helicobacter pylori protection against reflux esophagitis. Dig Dis Sci. 2012 Nov; 57(11):2924-8. PMID: 23010740.
      Citations: 10     Fields:    Translation:HumansCells
    166. Ramachandran L, Manu KA, Shanmugam MK, Li F, Siveen KS, Vali S, Kapoor S, Abbasi T, Surana R, Smoot DT, Ashktorab H, Tan P, Ahn KS, Yap CW, Kumar AP, Sethi G. Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor ? activation pathway in gastric cancer. J Biol Chem. 2012 Nov 02; 287(45):38028-40. PMID: 22992727.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    167. Wang R, L?hr CV, Fischer K, Dashwood WM, Greenwood JA, Ho E, Williams DE, Ashktorab H, Dashwood MR, Dashwood RH. Epigenetic inactivation of endothelin-2 and endothelin-3 in colon cancer. Int J Cancer. 2013 Mar 01; 132(5):1004-12. PMID: 22865632.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    168. Brim H, Lee E, Abu-Asab MS, Chaouchi M, Razjouyan H, Namin H, Goel A, Sch?ffer AA, Ashktorab H. Genomic aberrations in an African American colorectal cancer cohort reveals a MSI-specific profile and chromosome X amplification in male patients. PLoS One. 2012; 7(8):e40392. PMID: 22879877.
      Citations: 24     Fields:    Translation:HumansCells
    169. Cheng Y, Jin Z, Agarwal R, Ma K, Yang J, Ibrahim S, Olaru AV, David S, Ashktorab H, Smoot DT, Duncan MD, Hutcheon DF, Abraham JM, Meltzer SJ, Mori Y. LARP7 is a potential tumor suppressor gene in gastric cancer. Lab Invest. 2012 Jul; 92(7):1013-9. PMID: 22488152.
      Citations: 29     Fields:    Translation:HumansCells
    170. Ashktorab H, Green W, Finzi G, Sessa F, Nouraie M, Lee EL, Morgano A, Moschetta A, Cattaneo M, Mariani-Costantini R, Brim H, Biunno I. SEL1L, an UPR response protein, a potential marker of colonic cell transformation. Dig Dis Sci. 2012 Apr; 57(4):905-12. PMID: 22350780.
      Citations: 16     Fields:    Translation:HumansCells
    171. Kwagyan J, Apprey V, Ashktorab H. Linkage disequilibrium and haplotype analysis of COX-2 and risk of colorectal adenoma development. Clin Transl Sci. 2012 Feb; 5(1):60-4. PMID: 22376259.
      Citations: 3     Fields:    Translation:HumansCells
    172. Cai C, Ashktorab H, Pang X, Zhao Y, Sha W, Liu Y, Gu X. MicroRNA-211 expression promotes colorectal cancer cell growth in vitro and in vivo by targeting tumor suppressor CHD5. PLoS One. 2012; 7(1):e29750. PMID: 22235338.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    173. Ashktorab H, Nguza B, Fatemi M, Nouraie M, Smoot DT, Sch?ffer AA, Kupfer SS, Camargo CA, Brim H. Case-control study of vitamin D, dickkopf homolog 1 (DKK1) gene methylation, VDR gene polymorphism and the risk of colon adenoma in African Americans. PLoS One. 2011; 6(10):e25314. PMID: 22022386.
      Citations: 12     Fields:    Translation:HumansCells
    174. Ashktorab H, Nouri Z, Nouraie M, Razjouyan H, Lee EE, Dowlati E, El-Seyed el-W, Laiyemo A, Brim H, Smoot DT. Esophageal carcinoma in African Americans: a five-decade experience. Dig Dis Sci. 2011 Dec; 56(12):3577-82. PMID: 21847566.
      Citations: 10     Fields:    Translation:Humans
    175. Brim H, Kumar K, Nazarian J, Hathout Y, Jafarian A, Lee E, Green W, Smoot D, Park J, Nouraie M, Ashktorab H. SLC5A8 gene, a transporter of butyrate: a gut flora metabolite, is frequently methylated in African American colon adenomas. PLoS One. 2011; 6(6):e20216. PMID: 21687703.
      Citations: 16     Fields:    Translation:HumansCells
    176. Tao J, Deng NT, Ramnarayanan K, Huang B, Oh HK, Leong SH, Lim SS, Tan IB, Ooi CH, Wu J, Lee M, Zhang S, Rha SY, Chung HC, Smoot DT, Ashktorab H, Kon OL, Cacheux V, Yap C, Palanisamy N, Tan P. CD44-SLC1A2 gene fusions in gastric cancer. Sci Transl Med. 2011 Apr 06; 3(77):77ra30. PMID: 21471434.
      Citations: 33     Fields:    Translation:HumansCells
    177. Ahmadi L, Kamkari S, Mokarram P, Lankarani KB, Tabibi N, Ashktorab H, Vasei M. HER-2/neu and E-cadherin Expression and Microsatellite Instability in Gastric Dysplasia. Middle East J Dig Dis. 2011 Mar; 3(1):20-7. PMID: 25197528.
      Citations:    
    178. Wang R, Dashwood WM, Nian H, L?hr CV, Fischer KA, Tsuchiya N, Nakagama H, Ashktorab H, Dashwood RH. NADPH oxidase overexpression in human colon cancers and rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP). Int J Cancer. 2011 Jun 01; 128(11):2581-90. PMID: 20715105.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    179. Yang Y, Yixuan Y, Lim SK, Kiat LS, Choong LY, Yee CL, Lee H, Huiyin L, Chen Y, Yunhao C, Chong PK, Kuan CP, Ashktorab H, Hassan A, Wang TT, Ting WT, Salto-Tellez M, Manuel ST, Yeoh KG, Guan YK, Lim YP, Pin LY. Cathepsin S mediates gastric cancer cell migration and invasion via a putative network of metastasis-associated proteins. J Proteome Res. 2010 Sep 03; 9(9):4767-78. PMID: 20812763.
      Citations: 34     Fields:    Translation:HumansCells
    180. Chong PK, Lee H, Loh MC, Choong LY, Lin Q, So JB, Lim KH, Soo RA, Yong WP, Chan SP, Smoot DT, Ashktorab H, Yeoh KG, Lim YP. Upregulation of plasma C9 protein in gastric cancer patients. Proteomics. 2010 Sep; 10(18):3210-21. PMID: 20707004.
      Citations: 32     Fields:    Translation:HumansCells
    181. Zhang L, Hou Y, Ashktorab H, Gao L, Xu Y, Wu K, Zhai J, Zhang L. The impact of C-MYC gene expression on gastric cancer cell. Mol Cell Biochem. 2010 Nov; 344(1-2):125-35. PMID: 20737197.
      Citations: 36     Fields:    Translation:HumansCells
    182. Chong PK, Lee H, Zhou J, Liu SC, Loh MC, Wang TT, Chan SP, Smoot DT, Ashktorab H, So JB, Lim KH, Yeoh KG, Lim YP. ITIH3 is a potential biomarker for early detection of gastric cancer. J Proteome Res. 2010 Jul 02; 9(7):3671-9. PMID: 20515073.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    183. Nouraie M, Hosseinkhah F, Brim H, Zamanifekri B, Smoot DT, Ashktorab H. Clinicopathological features of colon polyps from African-Americans. Dig Dis Sci. 2010 May; 55(5):1442-9. PMID: 20225129.
      Citations: 23     Fields:    Translation:Humans
    184. Naghibalhossaini F, Mokarram P, Khalili I, Vasei M, Hosseini SV, Ashktorab H, Rasti M, Abdollahi K. MTHFR C677T and A1298C variant genotypes and the risk of microsatellite instability among Iranian colorectal cancer patients. Cancer Genet Cytogenet. 2010 Mar; 197(2):142-51. PMID: 20193847.
      Citations: 19     Fields:    Translation:Humans
    185. Ashktorab H, Sch?ffer AA, Daremipouran M, Smoot DT, Lee E, Brim H. Distinct genetic alterations in colorectal cancer. PLoS One. 2010 Jan 26; 5(1):e8879. PMID: 20126641.
      Citations: 69     Fields:    Translation:HumansCells
    186. Smoot DT, Collins J, Dunlap S, Ali-Ibrahim A, Nouraie M, Lee EL, Ashktorab H. Outcome of colonoscopy in elderly African-American patients. Dig Dis Sci. 2009 Nov; 54(11):2484-7. PMID: 19757049.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    187. Mokarram P, Kumar K, Brim H, Naghibalhossaini F, Saberi-firoozi M, Nouraie M, Green R, Lee E, Smoot DT, Ashktorab H. Distinct high-profile methylated genes in colorectal cancer. PLoS One. 2009 Sep 11; 4(9):e7012. PMID: 19750230.
      Citations: 81     Fields:    Translation:HumansCells
    188. Ashktorab H, Nouraie M, Hosseinkhah F, Lee E, Rotimi C, Smoot D. A 50-year review of colorectal cancer in African Americans: implications for prevention and treatment. Dig Dis Sci. 2009 Sep; 54(9):1985-90. PMID: 19554449.
      Citations: 14     Fields:    Translation:Humans
    189. Kumar K, Brim H, Giardiello F, Smoot DT, Nouraie M, Lee EL, Ashktorab H. Distinct BRAF (V600E) and KRAS mutations in high microsatellite instability sporadic colorectal cancer in African Americans. Clin Cancer Res. 2009 Feb 15; 15(4):1155-61. PMID: 19190129.
      Citations: 44     Fields:    Translation:HumansCells
    190. Ashktorab H, Belgrave K, Hosseinkhah F, Brim H, Nouraie M, Takkikto M, Hewitt S, Lee EL, Dashwood RH, Smoot D. Global histone H4 acetylation and HDAC2 expression in colon adenoma and carcinoma. Dig Dis Sci. 2009 Oct; 54(10):2109-17. PMID: 19057998.
      Citations: 53     Fields:    Translation:HumansCells
    191. Ashktorab H, Dashwood RH, Dashwood MM, Zaidi SI, Hewitt SM, Green WR, Lee EL, Daremipouran M, Nouraie M, Malekzadeh R, Smoot DT. H. pylori-induced apoptosis in human gastric cancer cells mediated via the release of apoptosis-inducing factor from mitochondria. Helicobacter. 2008 Dec; 13(6):506-17. PMID: 19166416.
      Citations: 22     Fields:    Translation:HumansCells
    192. Ashktorab H, Tsang S, Luke B, Sun Z, Adam-Campbell L, Kwagyan J, Poirier R, Akter S, Akhgar A, Smoot D, Munroe DJ, Ali IU. Protective effect of Cox-2 allelic variants on risk of colorectal adenoma development in African Americans. Anticancer Res. 2008 Sep-Oct; 28(5B):3119-23. PMID: 19031967.
      Citations: 6     Fields:    Translation:Humans
    193. Brim H, Mokarram P, Naghibalhossaini F, Saberi-Firoozi M, Al-Mandhari M, Al-Mawaly K, Al-Mjeni R, Al-Sayegh A, Raeburn S, Lee E, Giardiello F, Smoot DT, Vilkin A, Boland CR, Goel A, Hafezi M, Nouraie M, Ashktorab H. Impact of BRAF, MLH1 on the incidence of microsatellite instability high colorectal cancer in populations based study. Mol Cancer. 2008 Aug 21; 7:68. PMID: 18718023.
      Citations: 47     Fields:    Translation:Humans
    194. Ashktorab H, Brim H, Al-Riyami M, Date A, Al-Mawaly K, Kashoub M, Al-Mjeni R, Smoot DT, Al-Moundhri M, Al-Hashemi S, Ganguly SS, Raeburn S. Sporadic colon cancer: mismatch repair immunohistochemistry and microsatellite instability in Omani subjects. Dig Dis Sci. 2008 Oct; 53(10):2723-31. PMID: 18299982.
      Citations: 19     Fields:    Translation:HumansCells
    195. Ashktorab H, Daremipouran M, Wilson M, Siddiqi S, Lee EL, Rakhshani N, Malekzadeh R, Johnson AC, Hewitt SM, Smoot DT. Transactivation of the EGFR by AP-1 is induced by Helicobacter pylori in gastric cancer. Am J Gastroenterol. 2007 Oct; 102(10):2135-46. PMID: 17617207.
      Citations: 13     Fields:    Translation:HumansCells
    196. Ashktorab H, Begum R, Akhgar A, Smoot DT, Elbedawi M, Daremipouran M, Zhao A, Momen B, Giardiello FM. Folate status and risk of colorectal polyps in African Americans. Dig Dis Sci. 2007 Jun; 52(6):1462-70. PMID: 17372834.
      Citations: 15     Fields:    Translation:HumansCells
    197. Siavoshi F, Malekzadeh R, Daneshmand M, Ashktorab H. Helicobacter pylori endemic and gastric disease. Dig Dis Sci. 2005 Nov; 50(11):2075-80. PMID: 16240218.
      Citations: 24     Fields:    Translation:HumansCells
    198. Ashktorab H, Smoot DT, Farzanmehr H, Fidelia-Lambert M, Momen B, Hylind L, Iacosozio-Dononue C, Carethers JM, Goel A, Boland CR, Giardiello FM. Clinicopathological features and microsatellite instability (MSI) in colorectal cancers from African Americans. Int J Cancer. 2005 Oct 10; 116(6):914-9. PMID: 15856472.
      Citations: 43     Fields:    Translation:HumansCells
    199. Ashktorab H, Dawkins FW, Mohamed R, Larbi D, Smoot DT. Apoptosis induced by aspirin and 5-fluorouracil in human colonic adenocarcinoma cells. Dig Dis Sci. 2005 Jun; 50(6):1025-32. PMID: 15986848.
      Citations: 11     Fields:    Translation:HumansCells
    200. Siavoshi F, Malekzadeh R, Daneshmand M, Smoot DT, Ashktorab H. Association between Helicobacter pylori Infection in gastric cancer, ulcers and gastritis in Iranian patients. Helicobacter. 2004 Oct; 9(5):470. PMID: 15361089.
      Citations: 6     Fields:    Translation:HumansCells
    201. Ashktorab H, Frank S, Khaled AR, Durum SK, Kifle B, Smoot DT. Bax translocation and mitochondrial fragmentation induced by Helicobacter pylori. Gut. 2004 Jun; 53(6):805-13. PMID: 15138206.
      Citations: 20     Fields:    Translation:HumansCells
    202. Ashktorab H, Ahmed A, Littleton G, Wang XW, Allen CR, Tackey R, Walters C, Smoot DT. p53 and p14 increase sensitivity of gastric cells to H. pylori-induced apoptosis. Dig Dis Sci. 2003 Jul; 48(7):1284-91. PMID: 12870784.
      Citations: 4     Fields:    Translation:HumansCells
    203. Ashktorab H, Smoot DT, Carethers JM, Rahmanian M, Kittles R, Vosganian G, Doura M, Nidhiry E, Naab T, Momen B, Shakhani S, Giardiello FM, Shakhani S. High incidence of microsatellite instability in colorectal cancer from African Americans. Clin Cancer Res. 2003 Mar; 9(3):1112-7. PMID: 12631615.
      Citations: 56     Fields:    Translation:HumansCells
    204. Marlink KL, Bacon KD, Sheppard BC, Ashktorab H, Smoot DT, Cover TL, Deveney CW, Rutten MJ. Effects of Helicobacter pylori on intracellular Ca2+ signaling in normal human gastric mucous epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2003 Jul; 285(1):G163-76. PMID: 12606301.
      Citations: 20     Fields:    Translation:HumansCells
    205. Ashktorab H, Neapolitano M, Bomma C, Allen C, Ahmed A, Dubois A, Naab T, Smoot DT. In vivo and in vitro activation of caspase-8 and -3 associated with Helicobacter pylori infection. Microbes Infect. 2002 Jun; 4(7):713-22. PMID: 12067831.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    206. Akhtar M, Cheng Y, Magno RM, Ashktorab H, Smoot DT, Meltzer SJ, Wilson KT. Promoter methylation regulates Helicobacter pylori-stimulated cyclooxygenase-2 expression in gastric epithelial cells. Cancer Res. 2001 Mar 15; 61(6):2399-403. PMID: 11289104.
      Citations: 37     Fields:    Translation:HumansCells
    207. Smoot DT, Elliott TB, Verspaget HW, Jones D, Allen CR, Vernon KG, Bremner T, Kidd LC, Kim KS, Groupman JD, Ashktorab H. Influence of Helicobacter pylori on reactive oxygen-induced gastric epithelial cell injury. Carcinogenesis. 2000 Nov; 21(11):2091-5. PMID: 11062173.
      Citations: 36     Fields:    Translation:HumansCells
    208. Ahmed A, Smoot D, Littleton G, Tackey R, Walters CS, Kashanchi F, Allen CR, Ashktorab H. Helicobacter pylori inhibits gastric cell cycle progression. Microbes Infect. 2000 Aug; 2(10):1159-69. PMID: 11008106.
      Citations: 22     Fields:    Translation:Cells
    209. Smoot DT, Wynn Z, Elliott TB, Allen CR, Mekasha G, Naab T, Ashktorab H. Effects of Helicobacter pylori on proliferation of gastric epithelial cells in vitro. Am J Gastroenterol. 1999 Jun; 94(6):1508-11. PMID: 10364015.
      Citations: 13     Fields:    Translation:HumansCells
    210. Smoot DT, Hinds T, Ashktorab H, Jagtap J, Kim KS, Scott VF. Effectiveness of ranitidine bismuth citrate, clarithromycin, and metronidazole therapy for treating Helicobacter pylori. Am J Gastroenterol. 1999 Apr; 94(4):955-8. PMID: 10201463.
      Citations:    Fields:    Translation:HumansCellsCTClinical Trials
    211. Ashktorab H, Cohen RJ. Facile isolation of genomic DNA from filamentous fungi. Biotechniques. 1992 Aug; 13(2):198-200. PMID: 1389149.
      Citations: 7     Fields:    Translation:AnimalsCells
    212. Gazitt Y, He YJ, Erdos GW, Chang L, Ashktorab H, Cohen RJ. Development of a two color immunofluorescence stain and immunolocalization method for N-myc and c-myc oncoproteins with a newly generated mouse IgM anti N-myc antibody. J Immunol Methods. 1992 Apr 08; 148(1-2):159-69. PMID: 1564326.
      Citations:    Fields:    Translation:HumansCells
    213. Jensen SL, Ashktorab H, Hughes JE, Welker DL. Gene amplification associated with the dominant cob-354 cobalt resistance trait in Dictyostelium discoideum. Mol Gen Genet. 1989 Dec; 220(1):25-32. PMID: 2608027.
      Citations: 4     Fields:    Translation:Animals
    214. Ashktorab H, Srivastava A. Identification of nuclear proteins that specifically interact with adeno-associated virus type 2 inverted terminal repeat hairpin DNA. J Virol. 1989 Jul; 63(7):3034-9. PMID: 2542611.
      Citations: 57     Fields:    Translation:HumansCells
    215. Ashktorab H, Welker DL. Establishment of the nuclear location of Dictyostelium discoideum plasmids. Gene. 1988 May 15; 65(1):41-9. PMID: 3396881.
      Citations: 3     Fields:    Translation:AnimalsCells
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