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One or more keywords matched the following properties of McCarrey, John R.
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overview Research in Dr. McCarrey’s lab is centered on mammalian germ cells and stem cells. Experimental models include the mouse, the baboon, and the opossum. The lab is interested in the epigenetic regulation of cell functions, including determination of cell fates, maintenance of genetic integrity, regulation of gene expression, genomic imprinting, X-chromosome inactivation and meiotic sex chromosome inactivation, methods of assisted reproduction, the evolution of tissue-specific gene expression in mammalian species, and developing the baboon as a model system for testing stem cell-based therapeutic applications.
One or more keywords matched the following items that are connected to McCarrey, John R.
Item TypeName
Academic Article Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities.
Academic Article Many X-linked microRNAs escape meiotic sex chromosome inactivation.
Academic Article Sex chromosome inactivation in the male.
Academic Article Spermatogenesis as a model system for developmental analysis of regulatory mechanisms associated with tissue-specific gene expression.
Academic Article Developmental patterns of PPAR and RXR gene expression during spermatogenesis.
Academic Article Multiple elements influence transcriptional regulation from the human testis-specific PGK2 promoter in transgenic mice.
Academic Article Microarray-based analysis of cell-cycle gene expression during spermatogenesis in the mouse.
Academic Article Dynamic expression pattern and subcellular localization of the Rhox10 homeobox transcription factor during early germ cell development.
Academic Article Rsx is a metatherian RNA with Xist-like properties in X-chromosome inactivation.
Academic Article Human spermatogenesis as a model to examine gene potentiation.
Academic Article Computer-assisted annotation of murine Sertoli cell small RNA transcriptome.
Academic Article Enhanced genetic integrity in mouse germ cells.
Academic Article Sequence-specific promoter elements regulate temporal-specific changes in chromatin required for testis-specific activation of the Pgk2 gene.
Academic Article A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis.
Academic Article Semiquantitative analysis of X-linked gene expression during spermatogenesis in the mouse: ethidium-bromide staining of RT-PCR products.
Academic Article Expression of Xist in mouse germ cells correlates with X-chromosome inactivation.
Academic Article Differential transcription of Pgk genes during spermatogenesis in the mouse.
Academic Article Environmentally induced transgenerational epigenetic reprogramming of primordial germ cells and the subsequent germ line.
Academic Article Protein-DNA interactions associated with the onset of testis-specific expression of the mammalian Pgk-2 gene.
Academic Article Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line.
Academic Article A novel class of somatic small RNAs similar to germ cell pachytene PIWI-interacting small RNAs.
Academic Article Transcriptional and translational heterogeneity among neonatal mouse spermatogonia.
Academic Article Co-regulation of pluripotency and genetic integrity at the genomic level.
Academic Article Nucleotide sequence of the promoter region of a tissue-specific human retroposon: comparison with its housekeeping progenitor.
Academic Article Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene.
Academic Article Escape of X-linked miRNA genes from meiotic sex chromosome inactivation.
Academic Article Parallel evolution of male germline epigenetic poising and somatic development in animals.
Academic Article TSPAN8 Expression Distinguishes Spermatogonial Stem Cells in the Prepubertal Mouse Testis.
Academic Article Methylation patterns of testis-specific genes.
Academic Article EPIGENETICS. The epigenome--a family affair.
Academic Article The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.
Academic Article Tertiary Epimutations - A Novel Aspect of Epigenetic Transgenerational Inheritance Promoting Genome Instability.
Academic Article The ontogeny of allele-specific methylation associated with imprinted genes in the mouse.
Academic Article Construction of cDNA libraries from limiting amounts of material.
Academic Article Dynamic expression of long noncoding RNAs reveals their potential roles in spermatogenesis and fertility.
Academic Article Optimization of culture conditions for the derivation and propagation of baboon (Papio anubis) induced pluripotent stem cells.
Academic Article The Mammalian Spermatogenesis Single-Cell Transcriptome, from Spermatogonial Stem Cells to Spermatids.
Academic Article Differential gene expression in fetal mouse germ cells.
Academic Article Transcriptional analysis of the candidate spermatogenesis gene Ube1y and of the closely related Ube1x shows that they are coexpressed in spermatogonia and spermatids but are repressed in pachytene spermatocytes.
Academic Article Analysis of the cDNA and encoded protein of the human testis-specific PGK-2 gene.
Academic Article Transcriptional regulatory regions of testis-specific PGK2 defined in transgenic mice.
Academic Article A gene-specific promoter in transgenic mice directs testis-specific demethylation prior to transcriptional activation In vivo.
Academic Article Mutation frequency declines during spermatogenesis in young mice but increases in old mice.
Academic Article 9th International Congress on Isozymes, Genes, and Gene Families: an overview.
Academic Article Differentiation: the selective potentiation of chromatin domains.
Academic Article Reprogramming the male gamete genome: a window to successful gene therapy.
Academic Article Asynchronous replication of imprinted genes is established in the gametes and maintained during development.
Academic Article Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci.
Academic Article An abundance of X-linked genes expressed in spermatogonia.
Academic Article Characterization of the CDKN2A and ARF genes in UV-induced melanocytic hyperplasias and melanomas of an opossum (Monodelphis domestica).
Academic Article Absence of ras gene mutations in UV-induced malignant melanomas correlates with a dermal origin of melanocytes in Monodelphis domestica.
Academic Article X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse.
Academic Article The murine testicular transcriptome: characterizing gene expression in the testis during the progression of spermatogenesis.
Academic Article Spontaneous mutagenesis is enhanced in Apex heterozygous mice.
Academic Article The H19 methylation imprint is erased and re-established differentially on the parental alleles during male germ cell development.
Academic Article Ultraviolet B-induced melanoma in Monodelphis domestica occurs in the absence of alterations in the structure or expression of the p53 gene.
Academic Article Three novel spermatogenesis-specific zinc finger genes.
Academic Article Conservation of Dnmt1o cytosine methyltransferase in the marsupial Monodelphis domestica.
Academic Article Ontogeny of a demethylation domain and its relationship to activation of tissue-specific transcription.
Academic Article Identification, characterization, and functional analysis of sp1 transcript variants expressed in germ cells during mouse spermatogenesis.
Academic Article Differential expression of sex-linked and autosomal germ-cell-specific genes during spermatogenesis in the mouse.
Academic Article Gamete-specific methylation correlates with imprinting of the murine Xist gene.
Academic Article Epigenetic regulation of testis-specific gene expression.
Academic Article Testis and somatic Xrcc-1 DNA repair gene expression.
Academic Article Rat synapsin 1 promoter mediated transgene expression in testicular cell types.
Academic Article Developmental changes in methylation of spermatogenesis-specific genes include reprogramming in the epididymis.
Academic Article The search for a marsupial XIC reveals a break with vertebrate synteny.
Academic Article Autonomous regulation of sex-specific developmental programming in mouse fetal germ cells.
Academic Article Evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis.
Academic Article Cloning and expression profiling of testis-expressed piRNA-like RNAs.
Academic Article Differential appearance of DNase I-hypersensitive sites correlates with differential transcription of Pgk genes during spermatogenesis in the mouse.
Academic Article Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro.
Academic Article Recovery of a low mutant frequency after ionizing radiation-induced mutagenesis during spermatogenesis.
Academic Article Key features of the X inactivation process are conserved between marsupials and eutherians.
Academic Article In vivo analysis of developmentally and evolutionarily dynamic protein-DNA interactions regulating transcription of the Pgk2 gene during mammalian spermatogenesis.
Academic Article Cloning and expression profiling of testis-expressed microRNAs.
Academic Article Role of deoxyribonucleic acid polymerase epsilon in spermatogenesis in mice.
Academic Article A conserved E2F6-binding element in murine meiosis-specific gene promoters.
Concept Alleles
Concept Amino Acid Sequence
Concept Base Sequence
Concept DNA, Recombinant
Concept Gene Expression Regulation
Concept Gene Frequency
Concept Genes
Concept Genes, Bacterial
Concept Genes, Recessive
Concept Genes, Regulator
Concept Multigene Family
Concept Lac Operon
Concept Major Histocompatibility Complex
Concept Molecular Sequence Data
Concept Proto-Oncogenes
Concept Pseudogenes
Concept Genes, ras
Concept Repetitive Sequences, Nucleic Acid
Concept Sequence Homology, Nucleic Acid
Concept Gene Library
Concept Gene Expression
Concept Gene Expression Regulation, Enzymologic
Concept Genes, p53
Concept Reading Frames
Concept Open Reading Frames
Concept Genome
Concept Conserved Sequence
Concept Gene Deletion
Concept Sequence Homology, Amino Acid
Concept Genes, Reporter
Concept Gene Expression Regulation, Developmental
Concept Genes, cdc
Concept Transgenes
Concept Genes, p16
Concept Genes, Duplicate
Concept Gene Duplication
Concept Gene Silencing
Concept Gene Expression Profiling
Concept Genes, X-Linked
Concept Genes, Developmental
Concept Gene Regulatory Networks
Academic Article Determinator-inhibitor pairs as a mechanism for threshold setting in development: a possible function for pseudogenes.
Academic Article Is sex-specifically arranged repetitive DNA involved in primary sex determination of vertebrates?
Academic Article Genetics of scoliosis in chickens.
Academic Article OGG1 protects mouse spermatogonial stem cells from reactive oxygen species in culture?.
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