Research efforts center on the molecular mechanisms of host-pathogen interactions with the ultimate goal of engineering efficacious vaccine(s) against the pathogens. The role of epithelial cells in the recruitment, maintenance and effector functions of immune cells following Chlamydia infection of the reproductive tract, the pulmonary mucosa and protection are important to us. In cancer research, we are specifically interested in the mechanisms of immune surveillance, xenobiotic induced carcinogenesis and phytosterol induced protection against prostate neoplasm.