RCMI Coordinating Center (RCMI CC) Header Logo

Marcus Tius, PhD

Title
Faculty RankProfessor
InstitutionUniversity of Hawaii at Manoa
DepartmentChemistry, University of Hawaii Cancer Center
AddressUniversity of Hawaii Cancer Center
701 Ilalo St
Honolulu HI 96813
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    R01CA045288     (TIUS, MARCUS ANTONIUS)Jul 1, 1987 - Dec 31, 1990
    NIH
    LABELLED MARINE ANTITUMOR PROMOTERS
    Role: Principal Investigator
    R01GM038598     (TIUS, MARCUS ANTONIUS)Jul 1, 1987 - Dec 31, 1990
    NIH
    C-GLYCOSYL ANTHRAQUINONES
    Role: Principal Investigator
    R01DA006731     (TIUS, MARCUS ANTONIUS)Sep 30, 1990 - Aug 31, 1994
    NIH
    FUNCTIONALIZED CANNABINOIDS
    Role: Principal Investigator
    R01GM057873     (TIUS, MARCUS ANTONIUS)Aug 1, 1998 - Jan 31, 2013
    NIH
    Cyclopentannelation in Total Synthesis
    Role: Principal Investigator
    R01GM145845     (HAMANN, MARK T)Sep 1, 2022 - Jun 30, 2026
    NIH
    Synthesis and Optimization of the Aleutianamine Class of Alkaloids
    Role: Co-Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dickinson CF, Potluri A, Bland AM, Flipse SM, Hanna GS, Wagner RT, Robertson KD, Ho TH, Sprague DJ, Hoff GR, Stone RP, Tius MA, Tantillo DJ, Hamann MT. On the Discorhabdins Leading to the Aleutianamine Ring System: A One-Step in Situ Transformation Characterized Through Computational and Experimental Studies and Its Implications on Biosynthesis, Synthesis, and Pharmacology. Angew Chem Int Ed Engl. 2026 Apr 20; 65(17):e7864883. PMID: 41693117.
      Citations:    
    2. Dickinson CF, Flipse SM, Wood JS, Bistran E, Bland AM, Sprague DJ, DeJohn AM, Choo YM, Hanna GS, Yoshida WY, Williamson RT, Tius MA, Hamann MT. Aleutianamine B, A Novel Chiral Sulfoxide Isolated from Latrunculia spp. and Generated via Semi-Synthesis, Exhibits Selectivity for Ovarian Cancer Cells. J Nat Prod. 2026 Jan 23; 89(1):73-81. PMID: 41321182.
      Citations:    
    3. Bian T, Colomer G, Liu Y, Tius MA, Zhang Z. Deoxygenative Difunctionalization of Aldehydes via Ketyl Radical and Light/Dark Pd Synergy. Angew Chem Int Ed Engl. 2026 Jan 16; 65(3):e21847. PMID: 41316547.
      Citations:    
    4. Dickinson CF, Tian X, Yang JK, Baldridge KK, Yap GPA, Tius MA, Siegel JS. Chiral Semibuckminsterfullerene: Synthesis, Resolution, and Chiroptical Properties. Org Lett. 2025 Nov 07; 27(44):12259-12263. PMID: 41147864.
      Citations:    
    5. Liu X, Bian Z, Hu S, Dickinson CF, Benjamin MM, Jia J, Tian Y, Place A, Hanna GS, Luesch H, Croot P, Reddy MM, Thomas OP, Hardiman G, Puglisi MP, Yang M, Zhong Z, Lemasters JJ, Korte JE, Waters AL, Heltzel CE, Williamson RT, Strangman WK, Valeriote F, Tius MA, DiTullio GR, Ferreira D, Alekseyenko A, Wang S, Hamann MT, Wang X. The Chemistry of Phytoplankton. Chem Rev. 2024 Dec 11; 124(23):13099-13177. PMID: 39571071.
      Citations: 3     Fields:    Translation:HumansAnimals
    6. Chen Y, Zhai N, Zhu Y, Yue P, Verma N, Brotherton-Pleiss C, Fu W, Nakamura K, Chen W, Kawakami J, Murali R, Tius MA, Lopez-Tapia F, Turkson J. Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3. Bioorg Med Chem Lett. 2024 01 01; 97:129565. PMID: 38008341.
      Citations: 1     Fields:    
    7. Dickinson CF, Yap GPA, Tius MA. Anion-accelerated asymmetric Nazarov cyclization: access to vicinal all-carbon quaternary stereocenters. Org Biomol Chem. 2023 Jun 21; 21(24):5014-5020. PMID: 37265330.
      Citations:    Fields:    
    8. Zhu Y, Yue P, Dickinson CF, Yang JK, Datanagan K, Zhai N, Zhang Y, Miklossy G, Lopez-Tapia F, Tius MA, Turkson J. Natural product preferentially targets redox and metabolic adaptations and aberrantly active STAT3 to inhibit breast tumor growth in vivo. Cell Death Dis. 2022 12 06; 13(12):1022. PMID: 36473850.
      Citations: 6     Fields:    Translation:HumansAnimals
    9. Dickinson CF, Yang JK, Tius MA. Fluorine on fluorenes. Org Biomol Chem. 2022 Nov 16; 20(44):8615-8617. PMID: 36314529.
      Citations:    Fields:    
    10. Dickinson CF, Yang JK, Yap GPA, Tius MA. Modular Synthesis of a Semibuckminsterfullerene. Org Lett. 2022 07 22; 24(28):5095-5098. PMID: 35819411.
      Citations: 1     Fields:    
    11. Ho TC, Mullins JJ, Tius MA, Nikas SP, Tran NK, Tong F, Zvonok N, Makriyannis A. Corrigendum to "Oxa-adamantyl cannabinoids" [Bioorg. Med. Chem. Lett. 38 (2021) 127882]. Bioorg Med Chem Lett. 2022 Sep 15; 72:128836. PMID: 35803774.
      Citations:    Fields:    
    12. Yue P, Zhu Y, Brotherton-Pleiss C, Fu W, Verma N, Chen J, Nakamura K, Chen W, Chen Y, Alonso-Valenteen F, Mikhael S, Medina-Kauwe L, Kershaw KM, Celeridad M, Pan S, Limpert AS, Sheffler DJ, Cosford NDP, Shiao SL, Tius MA, Lopez-Tapia F, Turkson J. Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo. Cancer Lett. 2022 05 28; 534:215613. PMID: 35276290.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    13. Dickinson CF, Yap GPA, Tius MA. Synthesis of Fluorenes and Dibenzo[g,p]chrysenes through an Oxidative Cascade. J Org Chem. 2022 01 21; 87(2):1559-1563. PMID: 35014253.
      Citations:    Fields:    Translation:Cells
    14. Fu Y, Katsaros D, Biglia N, Wang Z, Pagano I, Tius M, Tiirikainen M, Rosser C, Yang H, Yu H. Vitamin D receptor upregulates lncRNA TOPORS-AS1 which inhibits the Wnt/?-catenin pathway and associates with favorable prognosis of ovarian cancer. Sci Rep. 2021 04 05; 11(1):7484. PMID: 33820921.
      Citations: 13     Fields:    Translation:HumansCells
    15. Ho TC, Tius MA, Nikas SP, Tran NK, Tong F, Zhou H, Zvonok N, Makriyannis A. Oxa-adamantyl cannabinoids. Bioorg Med Chem Lett. 2021 04 15; 38:127882. PMID: 33636308.
      Citations: 2     Fields:    Translation:HumansCells
    16. Brotherton-Pleiss C, Yue P, Zhu Y, Nakamura K, Chen W, Fu W, Kubota C, Chen J, Alonso-Valenteen F, Mikhael S, Medina-Kauwe L, Tius MA, Lopez-Tapia F, Turkson J. Discovery of Novel Azetidine Amides as Potent Small-Molecule STAT3 Inhibitors. J Med Chem. 2021 01 14; 64(1):695-710. PMID: 33352047.
      Citations: 5     Fields:    Translation:HumansCells
    17. Liu C, Yap GPA, Rowland CA, Tius MA. (Z)-Trifluoromethyl-Trisubstituted Alkenes or Isoxazolines: Divergent Pathways from the Same Allene. Org Lett. 2020 09 18; 22(18):7208-7212. PMID: 32876462.
      Citations:    Fields:    
    18. Lopez-Tapia F, Brotherton-Pleiss C, Yue P, Murakami H, Costa Araujo AC, Reis Dos Santos B, Ichinotsubo E, Rabkin A, Shah R, Lantz M, Chen S, Tius MA, Turkson J. Linker Variation and Structure-Activity Relationship Analyses of Carboxylic Acid-based Small Molecule STAT3 Inhibitors. ACS Med Chem Lett. 2018 Mar 08; 9(3):250-255. PMID: 29541369.
      Citations:    
    19. Ho TC, Shimada N, Tius MA, Nikas SP, Zhang W, Makriyannis A. C1'-Azacycloalkyl Hexahydrocannabinols. J Org Chem. 2017 08 04; 82(15):7839-7849. PMID: 28677397.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    20. Zhou Z, Dixon DD, Jolit A, Tius MA. The Evolution of the Total Synthesis of Rocaglamide. Chemistry. 2016 Oct 24; 22(44):15929-15936. PMID: 27717051.
      Citations: 6     Fields:    Translation:Cells
    21. Asari AH, Lam YH, Tius MA, Houk KN. Origins of the Stereoselectivity in a Thiourea-Primary Amine-Catalyzed Nazarov Cyclization. J Am Chem Soc. 2015 Oct 14; 137(40):13191-9. PMID: 26426475.
      Citations: 4     Fields:    Translation:Cells
    22. Zhou Z, Walleser PM, Tius MA. Isotetronic acids from an oxidative cyclization. Chem Commun (Camb). 2015 Jul 11; 51(54):10858-60. PMID: 26050998.
      Citations: 2     Fields:    Translation:Cells
    23. Yue P, Lopez-Tapia F, Paladino D, Li Y, Chen CH, Namanja AT, Hilliard T, Chen Y, Tius MA, Turkson J. Hydroxamic Acid and Benzoic Acid-Based STAT3 Inhibitors Suppress Human Glioma and Breast Cancer Phenotypes In Vitro and In Vivo. Cancer Res. 2016 Feb 01; 76(3):652-63. PMID: 26088127.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    24. Miller CM, Benneche T, Tius MA. First total synthesis of the marine natural products clavulolactones II and III. Org Biomol Chem. 2015 Apr 07; 13(13):4051-8. PMID: 25733336.
      Citations:    Fields:    
    25. Kitamura K, Shimada N, Stewart C, Atesin AC, Atesin TA, Tius MA. Enantioselective palladium(0)-catalyzed Nazarov-type cyclization. Angew Chem Int Ed Engl. 2015 May 18; 54(21):6288-91. PMID: 25833716.
      Citations: 5     Fields:    Translation:Cells
    26. Zhou Z, Tius MA. Synthesis of each enantiomer of rocaglamide by means of a palladium(0)-catalyzed Nazarov-type cyclization. Angew Chem Int Ed Engl. 2015 May 11; 54(20):6037-40. PMID: 25824525.
      Citations: 7     Fields:    Translation:Cells
    27. Ogawa G, Tius MA, Zhou H, Nikas SP, Halikhedkar A, Mallipeddi S, Makriyannis A. 3'-functionalized adamantyl cannabinoid receptor probes. J Med Chem. 2015 Apr 09; 58(7):3104-16. PMID: 25760146.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    28. Pratt LM, Dixon DD, Tius MA. Mixed aggregates of 1-methoxyallenyllithium with lithium chloride. ChemistryOpen. 2014 Dec; 3(6):250-5. PMID: 25558443.
      Citations:    Fields:    
    29. Jolit A, Walleser PM, Yap GP, Tius MA. Catalytic enantioselective Nazarov cyclization: construction of vicinal all-carbon-atom quaternary stereocenters. Angew Chem Int Ed Engl. 2014 Jun 10; 53(24):6180-3. PMID: 24838340.
      Citations: 16     Fields:    Translation:Cells
    30. Tius MA. Allene ether Nazarov cyclization. Chem Soc Rev. 2014 May 07; 43(9):2979-3002. PMID: 24196585.
      Citations: 15     Fields:    Translation:Cells
    31. Jolit A, Vazquez-Rodriguez S, Yap GP, Tius MA. Diastereospecific nazarov cyclization of fully substituted dienones: generation of vicinal all-carbon-atom quaternary stereocenters. Angew Chem Int Ed Engl. 2013 Oct 11; 52(42):11102-5. PMID: 24002922.
      Citations: 2     Fields:    Translation:Cells
    32. Dixon DD, Tius MA, Thakur GA, Zhou H, Bowman AL, Shukla VG, Peng Y, Makriyannis A. C3-heteroaroyl cannabinoids as photolabeling ligands for the CB2 cannabinoid receptor. Bioorg Med Chem Lett. 2012 Aug 15; 22(16):5322-5. PMID: 22796181.
      Citations: 10     Fields:    Translation:HumansCells
    33. Shimada N, Stewart C, Bow WF, Jolit A, Wong K, Zhou Z, Tius MA. Neutral Nazarov-type cyclization catalyzed by palladium(0). Angew Chem Int Ed Engl. 2012 Jun 04; 51(23):5727-9. PMID: 22539448.
      Citations: 8     Fields:    Translation:Cells
    34. Shimada N, Stewart C, Tius MA. Asymmetric Nazarov Cyclizations. Tetrahedron. 2011 Aug 19; 67(33):5851-5870. PMID: 21857751.
      Citations: 31     Fields:    
    35. Dixon DD, Sethumadhavan D, Benneche T, Banaag AR, Tius MA, Thakur GA, Bowman A, Wood JT, Makriyannis A. Heteroadamantyl cannabinoids. J Med Chem. 2010 Aug 12; 53(15):5656-66. PMID: 20593789.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    36. Basak AK, Shimada N, Bow WF, Vicic DA, Tius MA. An organocatalytic asymmetric Nazarov cyclization. J Am Chem Soc. 2010 Jun 23; 132(24):8266-7. PMID: 20507121.
      Citations: 25     Fields:    Translation:Cells
    37. Shimada N, Ashburn BO, Basak AK, Bow WF, Vicic DA, Tius MA. Organocatalytic asymmetric aza-Nazarov cyclization of an azirine. Chem Commun (Camb). 2010 Jun 07; 46(21):3774-5. PMID: 20428578.
      Citations: 8     Fields:    Translation:Cells
    38. Bow WF, Basak AK, Jolit A, Vicic DA, Tius MA. Enamine-iminium ion Nazarov cyclization of alpha-ketoenones. Org Lett. 2010 Feb 05; 12(3):440-3. PMID: 20030316.
      Citations: 18     Fields:    Translation:Cells
    39. Dixon DD, Tius MA, Pratt LM. Gas phase and solution structures of 1-methoxyallenyllithium. J Org Chem. 2009 Aug 21; 74(16):5881-6. PMID: 20560562.
      Citations: 1     Fields:    Translation:Cells
    40. Banaag AR, Tius MA. Traceless chiral auxiliaries for the allene ether Nazarov cyclization. J Org Chem. 2008 Nov 07; 73(21):8133-41. PMID: 18808186.
      Citations: 9     Fields:    Translation:Cells
    41. Basak AK, Tius MA. Interrupting the Nazarov cyclization with indoles. Org Lett. 2008 Sep 18; 10(18):4073-6. PMID: 18720989.
      Citations: 2     Fields:    Translation:Cells
    42. Binder CM, Dixon DD, Almaraz E, Tius MA, Singaram B. A Simple Procedure for C-C Bond Cleavage of Aromatic and Aliphatic Epoxides with Aqueous Sodium Periodate Under Ambient Conditions. Tetrahedron Lett. 2008 Apr 21; 49(17):2764-2767. PMID: 19946457.
      Citations: 6     Fields:    
    43. Berger GO, Tius MA. Total synthesis of (+/-)-terpestacin and (+/-)-11-epi-terpestacin. J Org Chem. 2007 Aug 17; 72(17):6473-80. PMID: 17630803.
      Citations: 8     Fields:    Translation:Cells
    44. Dhoro F, Kristensen TE, Stockmann V, Yap GP, Tius MA. Asymmetric amine-intercepted Nazarov cyclization. J Am Chem Soc. 2007 Jun 13; 129(23):7256-7. PMID: 17508753.
      Citations: 19     Fields:    Translation:Cells
    45. Banaag AR, Tius MA. Design of chiral auxiliaries for the allene ether nazarov cyclization. J Am Chem Soc. 2007 May 02; 129(17):5328-9. PMID: 17425314.
      Citations: 6     Fields:    Translation:Cells
    46. Wan L, Tius MA. Synthesis of (+)-madindoline A and (+)-madindoline B. Org Lett. 2007 Feb 15; 9(4):647-50. PMID: 17286372.
      Citations: 6     Fields:    Translation:Cells
    47. Le Goanvic D, Tius MA. Oxaza adamantyl cannabinoids. A new class of cannabinoid receptor probes. J Org Chem. 2006 Sep 29; 71(20):7800-4. PMID: 16995689.
      Citations: 6     Fields:    Translation:Animals
    48. delos Santos DB, Banaag AR, Tius MA. An improved chiral auxiliary for the allene ether version of the Nazarov cyclization. Org Lett. 2006 Jun 08; 8(12):2579-82. PMID: 16737318.
      Citations: 5     Fields:    Translation:Cells
    49. Berger GO, Tius MA. Terpestacin core structure. control of stereochemistry. Org Lett. 2005 Oct 27; 7(22):5011-3. PMID: 16235945.
      Citations: 3     Fields:    Translation:Cells
    50. Dhoro F, Tius MA. Interrupted Nazarov cyclization on silica gel. J Am Chem Soc. 2005 Sep 14; 127(36):12472-3. PMID: 16144378.
      Citations: 12     Fields:    Translation:Cells
    51. Batson WA, Sethumadhavan D, Tius MA. Alpha-hydroxy cyclopentenones from alpha-diketones. Org Lett. 2005 Jun 23; 7(13):2771-4. PMID: 15957943.
      Citations: 7     Fields:    Translation:Cells
    52. Bee C, Leclerc E, Tius MA. The palladium(II)-catalyzed Nazarov reaction. Org Lett. 2003 Dec 25; 5(26):4927-30. PMID: 14682731.
      Citations: 8     Fields:    Translation:Cells
    53. Forest J, Bee C, Cordaro F, Tius MA. Isomerization-cyclization approach to the synthesis of 2-hydroxy-5-alkylidene-cyclopent-2-enones. Org Lett. 2003 Oct 30; 5(22):4069-72. PMID: 14572251.
      Citations: 3     Fields:    Translation:Cells
    54. Bee C, Tius MA. Convergent cyclopentannelation process. Org Lett. 2003 May 15; 5(10):1681-4. PMID: 12735751.
      Citations: 2     Fields:    Translation:Cells
    55. Leclerc E, Tius MA. The first example of Nazarov reactions of vinyl cumulenyl ketones. Org Lett. 2003 Apr 17; 5(8):1171-4. PMID: 12688711.
      Citations: 5     Fields:    Translation:Cells
    56. Tius MA. Cationic cyclopentannelation of allene ethers. Acc Chem Res. 2003 Apr; 36(4):284-90. PMID: 12693926.
      Citations: 17     Fields:    Translation:Cells
    57. Chu C, Ramamurthy A, Makriyannis A, Tius MA. Synthesis of covalent probes for the radiolabeling of the cannabinoid receptor. J Org Chem. 2003 Jan 10; 68(1):55-61. PMID: 12515461.
      Citations: 4     Fields:    Translation:Cells
    58. Thakur GA, Palmer SL, Harrington PE, Stergiades IA, Tius MA, Makriyannis A. Enantiomeric resolution of a novel chiral cannabinoid receptor ligand. J Biochem Biophys Methods. 2002 Dec 31; 54(1-3):415-22. PMID: 12543516.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    59. Nakazaki A, Sharma U, Tius MA. Synthesis of the hydroazulene portion of guanacastepene A from the cyclopentannelation reaction. Org Lett. 2002 Oct 03; 4(20):3363-6. PMID: 12323019.
      Citations: 2     Fields:    Translation:AnimalsCells
    60. Harrington PE, Murai T, Chu C, Tius MA. Asymmetric cyclopentannelation: camphor-derived auxiliary. J Am Chem Soc. 2002 Aug 28; 124(34):10091-100. PMID: 12188673.
      Citations: 10     Fields:    Translation:Cells
    61. Li LH, Tius MA. Stereospecific synthesis of cryptophycin 1. Org Lett. 2002 May 16; 4(10):1637-40. PMID: 12000261.
      Citations: 5     Fields:    Translation:Cells
    62. Schultz-Fademrecht C, Tius MA, Grimme S, Wibbeling B, Hoppe D. Synthesis of enantioenriched 5-alkylidene-2-cyclopentenones from chiral allenyl carbamates: generation of a chiral lithium allenolate and allylic activation for a conrotatory 4pi-electrocyclization. Angew Chem Int Ed Engl. 2002 May 03; 41(9):1532-5. PMID: 19750656.
      Citations: 1     Fields:    
    63. Harrington PE, Tius MA. Synthesis and absolute stereochemistry of roseophilin. J Am Chem Soc. 2001 Sep 05; 123(35):8509-14. PMID: 11525658.
      Citations: 16     Fields:    Translation:Cells
    64. Jang WB, Hu H, Lieberman MM, Morgan JA, Stergiades IA, Clark DS, Tius MA. Parallel synthesis and biocatalytic amplification of a cross-conjugated cyclopentenone library. J Comb Chem. 2001 Jul-Aug; 3(4):346-53. PMID: 11442391.
      Citations: 1     Fields:    Translation:AnimalsCells
    65. Harrington PE, Stergiades IA, Erickson J, Makriyannis A, Tius MA. Synthesis of functionalized cannabinoids. J Org Chem. 2000 Oct 06; 65(20):6576-82. PMID: 11052105.
      Citations: 4     Fields:    Translation:AnimalsCells
    66. Harrington PE, Tius MA. Asymmetric cyclopentannelation. Chiral auxiliary on the allene. Org Lett. 2000 Aug 10; 2(16):2447-50. PMID: 10956518.
      Citations: 5     Fields:    Translation:Cells
    67. Harrington PE, Tius MA. A formal total synthesis of roseophilin: cyclopentannelation approach to the macrocyclic core. Org Lett. 1999 Aug 26; 1(4):649-51. PMID: 10823195.
      Citations: 8     Fields:    Translation:Cells
    68. Liang J, Hoard DW, Khau VV, Martinelli MJ, Moher ED, Moore RE, Tius MA. Synthesis of Unit A of Cryptophycin via a [2,3]-Wittig Rearrangement. J Org Chem. 1999 Mar 05; 64(5):1459-1463. PMID: 11674204.
      Citations: 3     Fields:    
    69. Drake DJ, Jensen RS, Busch-Petersen J, Kawakami JK, Concepcion Fernandez-Garcia M, Fan P, Makriyannis A, Tius MA. Classical/nonclassical hybrid cannabinoids: southern aliphatic chain-functionalized C-6beta methyl, ethyl, and propyl analogues. J Med Chem. 1998 Sep 10; 41(19):3596-608. PMID: 9733485.
      Citations: 5     Fields:    Translation:AnimalsCells
    70. Tius MA, Hu H, Kawakami JK, Busch-Petersen J. Synthesis of 15-Deoxy-12-hydroxy-10-(trifluoromethyl)-Delta(7)-PGA(1) Methyl Ester. J Org Chem. 1998 Aug 21; 63(17):5971-5976. PMID: 11672201.
      Citations: 2     Fields:    
    71. Biswas DK, Mhashilkar AM, Ewaniuk DS, Pezza JA, Oh LM, Kannangara GS, Tius MA, Pardee AB. Inhibition of HIV-1 replication by combination of a novel inhibitor of TNF-alpha with AZT. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Aug 15; 18(5):426-34. PMID: 9715838.
      Citations: 3     Fields:    Translation:HumansCells
    72. Busch-Petersen J, Hill WA, Fan P, Khanolkar A, Xie XQ, Tius MA, Makriyannis A. Unsaturated side chain beta-11-hydroxyhexahydrocannabinol analogs. J Med Chem. 1996 Sep 13; 39(19):3790-6. PMID: 8809166.
      Citations: 11     Fields:    Translation:AnimalsCells
    73. Komori A, Okabe S, Suganuma M, Kerr MA, Busch-Petersen J, Oh LM, Zhuo J, Kannangara GS, Zou X, Tius MA, Fujiki H. Anti-tumor promoting activity of canventol and its synthetic analogs through inhibition of protein isoprenylation. Jpn J Cancer Res. 1996 Sep; 87(9):875-81. PMID: 8878447.
      Citations:    Fields:    Translation:AnimalsCells
    74. Tius MA, Hill WA, Zou XL, Busch-Petersen J, Kawakami JK, Fernandez-Garcia MC, Drake DJ, Abadji V, Makriyannis A. Classical/non-classical cannabinoid hybrids; stereochemical requirements for the southern hydroxyalkyl chain. Life Sci. 1995; 56(23-24):2007-12. PMID: 7776825.
      Citations: 2     Fields:    Translation:AnimalsCells
    75. Komori A, Suganuma M, Okabe S, Zou X, Tius MA, Fujiki H. Canventol inhibits tumor promotion in CD-1 mouse skin through inhibition of tumor necrosis factor alpha release and of protein isoprenylation. Cancer Res. 1993 Aug 01; 53(15):3462-4. PMID: 8339247.
      Citations: 4     Fields:    Translation:AnimalsCells
    Tius's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (158)
    Explore
    _
    Co-Authors (2)
    Explore
    _
    Similar People (60)
    Explore
    _
    RCMI CC is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH

    For technical support please contact support