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Marian Manciu

TitleDr.
Faculty RankAssociate Professor
InstitutionUniversity of Texas at El Paso
DepartmentPhysics
Address500 W Uni Ave.
El Paso TX 79968
Phone9157477531
Fax9157475447
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    Collapse Overview 
    Collapse overview
    My research interests related to Translational Research are applications of advanced statistical modelling to a variety of clinical and biological data. They focus on:

    Survival analysis – Cox proportional hazard model, maximum-likelihood (ML) methods, parametric and non-parametric statistical estimations.

    Dimensionality reduction techniques- principal component analysis (PCA), factor analysis, discriminant analysis, and cluster analysis.

    Monte-Carlo methods.

    My main research expertise is in water-mediated macromolecular interactions. We developed statistical models for interactions between polar surfaces (proteins), between hydrophobic surfaces (lipids) and between grafted polymer brushes (biopolymers attached/adsorbed on surfaces). An updated list of publications can be find at:

    https://scholar.google.com/citations?user=mHCSCqYAAAAJ&hl=en


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Manciu FS, Guerrero J, Bennet KE, Chang SY, Rahman M, Martinez Lopez LV, Chantigian S, Castellanos M, Manciu M. Assessing Nordihydroguaiaretic Acid Therapeutic Effect for Glioblastoma Multiforme. Sensors (Basel). 2022 Mar 30; 22(7). PMID: 35408257.
      Citations: 5     Fields:    Translation:Humans
    2. Valenzuela P, Oaxaca D, Di Desidero T, Parra K, Rodriguez G, Manciu M, Allegrini G, Falcone A, Bocci G, Kirken RA, Francia G. Pharmacodynamic biomarkers in metronomic chemotherapy: multiplex cytokine measurements in gastrointestinal cancer patients. Clin Exp Med. 2021 Feb; 21(1):149-159. PMID: 33048259.
      Citations: 4     Fields:    Translation:Humans
    3. Manciu M, Cardenas M, Bennet KE, Maran A, Yaszemski MJ, Maldonado TA, Magiricu D, Manciu FS. Assessment of Renal Osteodystrophy via Computational Analysis of Label-free Raman Detection of Multiple Biomarkers. Diagnostics (Basel). 2020 Jan 31; 10(2). PMID: 32023980.
      Citations:    
    4. Manciu FS, Manciu M, Ciubuc JD, Sundin EM, Ochoa K, Eastman M, Durrer WG, Guerrero J, Lopez B, Subedi M, Bennet KE. Simultaneous Detection of Dopamine and Serotonin-A Comparative Experimental and Theoretical Study of Neurotransmitter Interactions. Biosensors (Basel). 2018 Dec 26; 9(1). PMID: 30587770.
      Citations: 3     Fields:    Translation:Humans
    5. Manciu M, Hosseini S, Di Desidero T, Allegrini G, Falcone A, Bocci G, Kirken RA, Francia G. Optimization of biomarkers-based classification scores as progression-free survival predictors: an intuitive graphical representation. Future Sci OA. 2018 12; 4(10):FSO346. PMID: 30450233.
      Citations:    
    6. Ciubuc JD, Manciu M, Maran A, Yaszemski MJ, Sundin EM, Bennet KE, Manciu FS. Raman Spectroscopic and Microscopic Analysis for Monitoring Renal Osteodystrophy Signatures. Biosensors (Basel). 2018 Apr 08; 8(2). PMID: 29642494.
      Citations: 3     Fields:    Translation:Humans
    7. Manciu M, Trevino R, Mulla ZD, Cortez C, Plavsic SK. Detection of Biased Rating of Medical Students by Standardized Patients: Opportunity for Improvement. Med Sci Educ. 2017 Sep; 27(3):497-502. PMID: 29104814.
      Citations:    
    8. Parra K, Valenzuela P, Lerma N, Gallegos A, Reza LC, Rodriguez G, Emmenegger U, Di Desidero T, Bocci G, Felder MS, Manciu M, Kirken RA, Francia G. Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth. Br J Cancer. 2017 01; 116(3):324-334. PMID: 28056464.
      Citations: 26     Fields:    Translation:AnimalsCells
    9. Manciu FS, Ciubuc JD, Parra K, Manciu M, Bennet KE, Valenzuela P, Sundin EM, Durrer WG, Reza L, Francia G. Label-Free Raman Imaging to Monitor Breast Tumor Signatures. Technol Cancer Res Treat. 2017 08; 16(4):461-469. PMID: 27381847.
      Citations: 9     Fields:    Translation:HumansCells
    10. Manciu M, Manciu FS, Ruckenstein E. On the surface tension and Zeta potential of electrolyte solutions. Adv Colloid Interface Sci. 2017 Jun; 244:90-99. PMID: 27337997.
      Citations: 2     Fields:    
    11. Manciu FS, Manciu M, Durrer WG, Salazar JG, Lee KH, Bennet KE. A Drude model analysis of conductivity and free carriers in boron-doped diamond films and investigations of their internal stress and strain. J Mater Sci. 2014 Aug 01; 49(16):5782-5789. PMID: 25328245.
      Citations:    
    12. Manciu M, Bosse C, Ruckenstein E. Size-dependent transitions in grafted polymer brushes. J Phys Chem B. 2013 Aug 15; 117(32):9532-9. PMID: 23879714.
      Citations:    Fields:    
    13. Manciu M, Ruckenstein E. Loops, tails and trains: A simple model for structural transformations of grafted adsorbing neutral polymer brushes. J Colloid Interface Sci. 2011 Feb 01; 354(1):61-9. PMID: 21074164.
      Citations: 1     Fields:    Translation:Cells
    14. Manciu M, Manciu FS, Vulcan T, Nes E, Waggener RG. Robust megavoltage x-ray spectra estimation from transmission measurements. J Xray Sci Technol. 2009; 17(1):85-99. PMID: 19644215.
      Citations:    Fields:    
    15. Manciu M, Ruckenstein E. On possible microscopic origins of the swelling of neutral lipid bilayers induced by simple salts. J Colloid Interface Sci. 2007 May 01; 309(1):56-67. PMID: 17331528.
      Citations: 1     Fields:    
    16. Manciu M, Calvo O, Ruckenstein E. Polarization model for poorly-organized interfacial water: hydration forces between silica surfaces. Adv Colloid Interface Sci. 2006 Nov 23; 127(1):29-42. PMID: 17022933.
      Citations: 1     Fields:    
    17. Manciu M, Ruckenstein E. Ions at the air/water interface. J Colloid Interface Sci. 2006 Dec 15; 304(2):541-4. PMID: 17045284.
      Citations: 2     Fields:    
    18. Manciu M, Ruckenstein E. Polarization of water near dipolar surfaces: a simple model for anomalous dielectric behavior. Langmuir. 2005 Dec 06; 21(25):11749-56. PMID: 16316110.
      Citations: 2     Fields:    
    19. Manciu M, Ruckenstein E. On the interactions of ions with the air/water interface. Langmuir. 2005 Nov 22; 21(24):11312-9. PMID: 16285805.
      Citations: 2     Fields:    
    20. Huang H, Manciu M, Ruckenstein E. On the restabilization of protein-covered latex colloids at high ionic strengths. Langmuir. 2005 Jan 04; 21(1):94-9. PMID: 15620289.
      Citations: 4     Fields:    
    21. Manciu M, Ruckenstein E. The polarization model for hydration/double layer interactions: the role of the electrolyte ions. Adv Colloid Interface Sci. 2004 Dec 31; 112(1-3):109-28. PMID: 15581557.
      Citations: 3     Fields:    
    22. Manciu M, Ruckenstein E. On the monomer density of grafted polyelectrolyte brushes and their interactions. Langmuir. 2004 Sep 14; 20(19):8155-64. PMID: 15350087.
      Citations:    Fields:    
    23. Manciu M, Ruckenstein E. Simple model for grafted polymer brushes. Langmuir. 2004 Jul 20; 20(15):6490-500. PMID: 15248741.
      Citations:    Fields:    
    24. Ruckenstein E, Manciu M. Specific ion effects via ion hydration: II. Double layer interaction. Adv Colloid Interface Sci. 2003 Sep 18; 105:177-200. PMID: 12969645.
      Citations: 1     Fields:    
    25. Manciu M, Ruckenstein E. Specific ion effects via ion hydration: I. Surface tension. Adv Colloid Interface Sci. 2003 Sep 18; 105:63-101. PMID: 12969642.
      Citations: 9     Fields:    
    26. Huang H, Manciu M, Ruckenstein E. The effect of surface dipoles and of the field generated by a polarization gradient on the repulsive force. J Colloid Interface Sci. 2003 Jul 01; 263(1):156-61. PMID: 12804897.
      Citations: 2     Fields:    
    27. Sen S, Manciu M. Solitary wave dynamics in generalized Hertz chains: an improved solution of the equation of motion. Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Nov; 64(5 Pt 2):056605. PMID: 11736114.
      Citations: 1     Fields:    
    28. Manciu M, Sen S, Hurd AJ. Crossing of identical solitary waves in a chain of elastic beads. Phys Rev E Stat Nonlin Soft Matter Phys. 2001 Jan; 63(1 Pt 2):016614. PMID: 11304385.
      Citations: 1     Fields:    
    29. Manciu M, Tehan VN, Sen S. Dynamics of a gravitationally loaded chain of elastic beads. Chaos. 2000 Sep; 10(3):658-669. PMID: 12779415.
      Citations:    Fields:    
    30. Manaila R, Orton BR, Macovei D, Manciu M, Adil-Smith I. Bond hybridization in Au alloys: Extracting structural information from the x-ray-absorption white line. Phys Rev B Condens Matter. 1996 Apr 01; 53(13):8164-8167. PMID: 9982298.
      Citations:    
    31. Hociota D, Suciu M, Dimitriu T, Calarasu R, Dumitrescu V, Bacalbasa A, Manciu M, Marinescu A. [Classification of benign tumors with anatomoclinical comments on otorhinolaryngological localizations]. Rev Chir Oncol Radiol O R L Oftalmol Stomatol Otorinolaringol. 1984 Jan-Mar; 29(1):1-8. PMID: 6326205.
      Citations:    Fields:    Translation:Humans
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