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Deepa Bedi

TitleDr
Faculty RankAssistant Professor
InstitutionTuskegee University
DepartmentBiomedical Sciences
Address307A patterson hall
College of Veterinary Medicine
Tuskegee University
Tuskegee AL 36088
Phone3347278468
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    Collapse Research 
    Collapse research activities and funding
    SC2CA211028     (BEDI, DEEPA)Aug 30, 2016 - Jul 31, 2020
    NIH
    Phage Display to Identify Epithelial to Mesenchymal Transitioned (EMT) Breast Cancer Cells
    Role: Principal Investigator
    SC1GM136521     (BEDI, DEEPA)Aug 20, 2020 - Jul 31, 2024
    NIH
    Evaluation of HSPD1 (Heat Shock Protein, 60) as a theranostic target for breast cancer
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ahmed MSU, Lord BD, Adu Addai B, Singhal SK, Gardner K, Salam AB, Ghebremedhin A, White J, Mahmud I, Martini R, Bedi D, Lin H, Jones JD, Karanam B, Dean-Colomb W, Grizzle W, Wang H, Davis M, Yates CC. Immune Profile of Exosomes in African American Breast Cancer Patients Is Mediated by Kaiso/THBS1/CD47 Signaling. Cancers (Basel). 2023 Apr 13; 15(8). PMID: 37190208.
      Citations:    
    2. Hogans MD, Kretzschmar WP, Higgins TA, Chakrabortty A, Nance RL, Smith BF, Bedi D, Sandey M, Agarwal P. Characterization of Canine Adenovirus Type 2 Virus Infection Pattern in Canine and Human Cell Lines. Adv Virol. 2022; 2022:3658970. PMID: 36591003.
      Citations:    
    3. Angajala A, Raymond H, Muhammad A, Uddin Ahmed MS, Haleema S, Haque M, Wang H, Campbell M, Martini R, Karanam B, Kahn AG, Bedi D, Davis M, Tan M, Dean-Colomb W, Yates C. MicroRNAs within the Basal-like signature of Quadruple Negative Breast Cancer impact overall survival in African Americans. Sci Rep. 2022 12 22; 12(1):22178. PMID: 36550153.
      Citations: 1     Fields:    Translation:Humans
    4. Hassan M, Trung V, Bedi D, Shaddox S, Gunturu D, Yates C, Datta P, Samuel T. Interference with pathways activated by topoisomerase inhibition alters the surface expression of PD-L1 and MHC I in colon cancer cells. Oncol Lett. 2023 Jan; 25(1):41. PMID: 36589674.
      Citations:    
    5. King D, Khodary MG, Samuel T, Yates C, Bedi D. Obesity Influences the Expression of Key Immunomodulators in Normal Human Breast Tissue, Basal-like Breast Cancer Patients, and Cell Lines. Cancers (Basel). 2022 Nov 15; 14(22). PMID: 36428692.
      Citations:    
    6. Martini R, Delpe P, Chu TR, Arora K, Lord B, Verma A, Bedi D, Karanam B, Elhussin I, Chen Y, Gebregzabher E, Oppong JK, Adjei EK, Jibril Suleiman A, Awuah B, Muleta MB, Abebe E, Kyei I, Aitpillah FS, Adinku MO, Ankomah K, Osei-Bonsu EB, Chitale DA, Bensenhaver JM, Nathanson DS, Jackson L, Petersen LF, Proctor E, Stonaker B, Gyan KK, Gibbs LD, Monojlovic Z, Kittles RA, White J, Yates CC, Manne U, Gardner K, Mongan N, Cheng E, Ginter P, Hoda S, Elemento O, Robine N, Sboner A, Carpten JD, Newman L, Davis MB. African Ancestry-Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent. Cancer Discov. 2022 11 02; 12(11):2530-2551. PMID: 36121736.
      Citations: 17     Fields:    Translation:HumansCells
    7. Ruiz D, Haynes C, Marable J, Pundkar C, Nance RL, Bedi D, Agarwal P, Suryawanshi AS, Mishra A, Smith BF, Sandey M. Development of OX40 agonists for canine cancer immunotherapy. iScience. 2022 Oct 21; 25(10):105158. PMID: 36217551.
      Citations:    
    8. Marable J, Ruiz D, Jaiswal AK, Bhattacharya R, Pantazes R, Agarwal P, Suryawanshi AS, Bedi D, Mishra A, Smith BF, Sandey M. Nanobody-based CTLA4 inhibitors for immune checkpoint blockade therapy of canine cancer patients. Sci Rep. 2021 10 21; 11(1):20763. PMID: 34675296.
      Citations: 6     Fields:    Translation:Animals
    9. Bedi D, Henderson HJ, Manne U, Samuel T. Camptothecin Induces PD-L1 and Immunomodulatory Cytokines in Colon Cancer Cells. Medicines (Basel). 2019 Apr 24; 6(2). PMID: 31022845.
      Citations:    
    10. Angajala A, Mothershed E, Davis MB, Tripathi S, He Q, Bedi D, Dean-Colomb W, Yates C. Quadruple Negative Breast Cancers (QNBC) Demonstrate Subtype Consistency among Primary and Recurrent or Metastatic Breast Cancer. Transl Oncol. 2019 Mar; 12(3):493-501. PMID: 30594038.
      Citations:    
    11. Jones KM, Karanam B, Jones-Triche J, Sandey M, Henderson HJ, Samant RS, Temesgen S, Yates C, Bedi D. Phage Ligands for Identification of Mesenchymal-Like Breast Cancer Cells and Cancer-Associated Fibroblasts. Front Oncol. 2018; 8:625. PMID: 30619759.
      Citations:    
    12. Henderson HJ, Karanam B, Samant R, Vig K, Singh SR, Yates C, Bedi D. Neuroligin 4X overexpression in human breast cancer is associated with poor relapse-free survival. PLoS One. 2017; 12(12):e0189662. PMID: 29244827.
      Citations: 5     Fields:    Translation:HumansCells
    13. Bedi D, Dennis JC, Morrison EE, Braden TD, Judd RL. Regulation of intracellular trafficking and secretion of adiponectin by myosin II. Biochem Biophys Res Commun. 2017 08 19; 490(2):202-208. PMID: 28606474.
      Citations: 3     Fields:    Translation:AnimalsCells
    14. Gillespie JW, Gross AL, Puzyrev AT, Bedi D, Petrenko VA. Combinatorial synthesis and screening of cancer cell-specific nanomedicines targeted via phage fusion proteins. Front Microbiol. 2015; 6:628. PMID: 26157433.
      Citations:    
    15. Bedi D, Gillespie JW, Petrenko VA. Selection of pancreatic cancer cell-binding landscape phages and their use in development of anticancer nanomedicines. Protein Eng Des Sel. 2014 Jul; 27(7):235-43. PMID: 24899628.
      Citations: 13     Fields:    Translation:HumansCells
    16. Bedi D, Gillespie JW, Petrenko VA, Ebner A, Leitner M, Hinterdorfer P, Petrenko VA. Targeted delivery of siRNA into breast cancer cells via phage fusion proteins. Mol Pharm. 2013 Feb 04; 10(2):551-9. PMID: 23215008.
      Citations: 26     Fields:    Translation:HumansCells
    17. Dalal S, Hui D, Bidaut L, Lem K, Del Fabbro E, Crane C, Reyes-Gibby CC, Bedi D, Bruera E. Relationships among body mass index, longitudinal body composition alterations, and survival in patients with locally advanced pancreatic cancer receiving chemoradiation: a pilot study. J Pain Symptom Manage. 2012 Aug; 44(2):181-91. PMID: 22695045.
      Citations: 63     Fields:    Translation:Humans
    18. Fagbohun OA, Bedi D, Grabchenko NI, Deinnocentes PA, Bird RC, Petrenko VA. Landscape phages and their fusion proteins targeted to breast cancer cells. Protein Eng Des Sel. 2012 Jun; 25(6):271-83. PMID: 22490956.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    19. Wang T, Kulkarni N, Bedi D, D'Souza GG, Papahadjopoulos-Sternberg B, Petrenko VA, Torchilin VP. In vitro optimization of liposomal nanocarriers prepared from breast tumor cell specific phage fusion protein. J Drug Target. 2011 Sep; 19(8):597-605. PMID: 21275826.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    20. Bedi D, Musacchio T, Fagbohun OA, Gillespie JW, Deinnocentes P, Bird RC, Bookbinder L, Torchilin VP, Petrenko VA. Delivery of siRNA into breast cancer cells via phage fusion protein-targeted liposomes. Nanomedicine. 2011 Jun; 7(3):315-23. PMID: 21050894.
      Citations: 30     Fields:    Translation:HumansCells
    21. Horikawa S, Bedi D, Li S, Shen W, Huang S, Chen IH, Chai Y, Auad ML, Bozack MJ, Barbaree JM, Petrenko VA, Chin BA. Effects of surface functionalization on the surface phage coverage and the subsequent performance of phage-immobilized magnetoelastic biosensors. Biosens Bioelectron. 2011 Jan 15; 26(5):2361-7. PMID: 21084182.
      Citations: 4     Fields:    Translation:Cells
    22. Wang T, D'Souza GG, Bedi D, Fagbohun OA, Potturi LP, Papahadjopoulos-Sternberg B, Petrenko VA, Torchilin VP. Enhanced binding and killing of target tumor cells by drug-loaded liposomes modified with tumor-specific phage fusion coat protein. Nanomedicine (Lond). 2010 Jun; 5(4):563-74. PMID: 20528452.
      Citations: 37     Fields:    Translation:HumansCells
    23. Jayanna PK, Bedi D, Gillespie JW, DeInnocentes P, Wang T, Torchilin VP, Bird RC, Petrenko VA. Landscape phage fusion protein-mediated targeting of nanomedicines enhances their prostate tumor cell association and cytotoxic efficiency. Nanomedicine. 2010 Aug; 6(4):538-46. PMID: 20138246.
      Citations: 19     Fields:    Translation:HumansCells
    24. Brunson BL, Zhong Q, Clarke KJ, Bedi D, Braden TD, van Santen E, Judd RL. Serum concentrations of adiponectin and characterization of adiponectin protein complexes in dogs. Am J Vet Res. 2007 Jan; 68(1):57-62. PMID: 17199419.
      Citations: 5     Fields:    Translation:AnimalsCells
    25. Bedi D, Clarke KJ, Dennis JC, Zhong Q, Brunson BL, Morrison EE, Judd RL. Endothelin-1 inhibits adiponectin secretion through a phosphatidylinositol 4,5-bisphosphate/actin-dependent mechanism. Biochem Biophys Res Commun. 2006 Jun 23; 345(1):332-9. PMID: 16682005.
      Citations: 12     Fields:    Translation:AnimalsCells
    26. Bedrosian I, Bedi D, Kuerer HM, Fornage BD, Harker L, Ross MI, Ames FC, Krishnamurthy S, Edeiken-Monroe BS, Meric F, Feig BW, Akins J, Singletary SE, Mirza NQ, Hunt KK. Impact of clinicopathological factors on sensitivity of axillary ultrasonography in the detection of axillary nodal metastases in patients with breast cancer. Ann Surg Oncol. 2003 Nov; 10(9):1025-30. PMID: 14597440.
      Citations: 25     Fields:    Translation:HumansCTClinical Trials
    27. Edeiken BS, Fornage BD, Bedi DG, Sneige N, Parulekar SG, Pleasure J. Recurrence in autogenous myocutaneous flap reconstruction after mastectomy for primary breast cancer: US diagnosis. Radiology. 2003 May; 227(2):542-8. PMID: 12732703.
      Citations: 9     Fields:    Translation:Humans
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