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Robert Onyenwoke, PhD

Title
InstitutionNorth Carolina Central University
Address1801 Fayetteville St
Durham NC 27707
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Hanafi D, Onyenwoke RU, Kimbro KS. The G-Protein-Coupled Estrogen Receptor Selective Agonist G-1 Attenuates Cell Viability and Migration in High-Grade Serous Ovarian Cancer Cell Lines. Int J Mol Sci. 2024 Jun 13; 25(12). PMID: 38928205.
      Citations:    Fields:    Translation:HumansCells
    2. Walker-Franklin I, Onyenwoke RU, Leung T, Huang X, Shipman JG, Kovach A, Sivaraman V. GC/HRMS Analysis of E-Liquids Complements In Vivo Modeling Methods and can Help to Predict Toxicity. ACS Omega. 2024 Jun 18; 9(24):26641-26650. PMID: 38911720.
      Citations:    
    3. Shipman JG, Onyenwoke RU, Sivaraman V. Vaping-Dependent Pulmonary Inflammation Is Ca2+ Mediated and Potentially Sex Specific. Int J Mol Sci. 2024 Feb 01; 25(3). PMID: 38339063.
      Citations:    Fields:    Translation:Animals
    4. Alhadyan SK, Sivaraman V, Onyenwoke RU. E-cigarette Flavors, Sensory Perception, and Evoked Responses. Chem Res Toxicol. 2022 12 19; 35(12):2194-2209. PMID: 36480683.
      Citations: 2     Fields:    Translation:Animals
    5. Onyenwoke RU, Leung T, Huang X, Parker D, Shipman JG, Alhadyan SK, Sivaraman V. An assessment of vaping-induced inflammation and toxicity: A feasibility study using a 2-stage zebrafish and mouse platform. Food Chem Toxicol. 2022 May; 163:112923. PMID: 35318090.
      Citations: 5     Fields:    Translation:Animals
    6. Shipman JG, Onyenwoke RU, Sivaraman V. Calcium-Dependent Pulmonary Inflammation and Pharmacological Interventions and Mediators. Biology (Basel). 2021 Oct 16; 10(10). PMID: 34681152.
      Citations:    
    7. Zhang R, Jones MM, Parker D, Dornsife RE, Wymer N, Onyenwoke RU, Sivaraman V. Acute vaping exacerbates microbial pneumonia due to calcium (Ca2+) dysregulation. PLoS One. 2021; 16(8):e0256166. PMID: 34383849.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    8. Tarpley M, Oladapo H, Caligan TB, Onyenwoke RU, Williams KP. Data supporting a pilot high-throughput screen of a drug library for identification of DYRK1A inhibitors and high-content imaging analysis of identified harmine analogs. Data Brief. 2021 Aug; 37:107189. PMID: 34141844.
      Citations:    
    9. Tarpley M, Caligan TB, Onyenwoke RU, Williams KP. Optimization and validation of a DYRK1A TR-FRET assay for high-throughput screening. MethodsX. 2021; 8:101383. PMID: 34430279.
      Citations:    
    10. Sivaraman V, Parker D, Zhang R, Jones MM, Onyenwoke RU. Vaping Exacerbates Coronavirus-Related Pulmonary Infection in a Murine Model. Front Physiol. 2021; 12:634839. PMID: 34040540.
      Citations:    
    11. Sivaraman V, Onyenwoke RU. Calcium Signaling Derangement and Disease Development and Progression. Biology (Basel). 2021 Apr 02; 10(4). PMID: 33918192.
      Citations:    
    12. Tarpley M, Oladapo HO, Strepay D, Caligan TB, Chdid L, Shehata H, Roques JR, Thomas R, Laudeman CP, Onyenwoke RU, Darr DB, Williams KP. Identification of harmine and ?-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies. Eur J Pharm Sci. 2021 Jul 01; 162:105821. PMID: 33781856.
      Citations: 13     Fields:    Translation:Humans
    13. Zhang R, Jones MM, Dornsife RE, Wu T, Sivaraman V, Tarran R, Onyenwoke RU. JUUL e-liquid exposure elicits cytoplasmic Ca2+ responses and leads to cytotoxicity in cultured airway epithelial cells. Toxicol Lett. 2021 Feb 01; 337:46-56. PMID: 33253780.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    14. Ghosh A, Beyazcicek O, Davis ES, Onyenwoke RU, Tarran R. Cellular effects of nicotine salt-containing e-liquids. J Appl Toxicol. 2021 03; 41(3):493-505. PMID: 33034066.
      Citations: 11     Fields:    Translation:HumansCells
    15. Ehe BK, Lamson DR, Tarpley M, Onyenwoke RU, Graves LM, Williams KP. Data on peptides identified by mass spectrometry analysis of in vitro DYRK1A-mediated phosphorylation sites on GLI1. Data Brief. 2017 Dec; 15:577-583. PMID: 29071296.
      Citations:    
    16. Ehe BK, Lamson DR, Tarpley M, Onyenwoke RU, Graves LM, Williams KP. Identification of a DYRK1A-mediated phosphorylation site within the nuclear localization sequence of the hedgehog transcription factor GLI1. Biochem Biophys Res Commun. 2017 09 23; 491(3):767-772. PMID: 28735864.
      Citations: 18     Fields:    Translation:HumansCells
    17. Onyenwoke RU, Brenman JE. Lysosomal Storage Diseases-Regulating Neurodegeneration. J Exp Neurosci. 2015; 9(Suppl 2):81-91. PMID: 27081317.
      Citations:    
    18. Onyenwoke RU, Sexton JZ, Yan F, D?az MC, Forsberg LJ, Major MB, Brenman JE. The mucolipidosis IV Ca2+ channel TRPML1 (MCOLN1) is regulated by the TOR kinase. Biochem J. 2015 Sep 15; 470(3):331-42. PMID: 26195823.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    19. Swick LL, Kazgan N, Onyenwoke RU, Brenman JE. Isolation of AMP-activated protein kinase (AMPK) alleles required for neuronal maintenance in Drosophila melanogaster. Biol Open. 2013 Dec 15; 2(12):1321-3. PMID: 24337116.
      Citations: 5     Fields:    
    20. Onyenwoke RU, Forsberg LJ, Liu L, Williams T, Alzate O, Brenman JE. AMPK directly inhibits NDPK through a phosphoserine switch to maintain cellular homeostasis. Mol Biol Cell. 2012 Jan; 23(2):381-9. PMID: 22114351.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    21. Johnson EC, Kazgan N, Bretz CA, Forsberg LJ, Hector CE, Worthen RJ, Onyenwoke R, Brenman JE. Altered metabolism and persistent starvation behaviors caused by reduced AMPK function in Drosophila. PLoS One. 2010 Sep 20; 5(9). PMID: 20862213.
      Citations: 49     Fields:    Translation:Animals
    22. Onyenwoke RU, Geyer R, Wiegel J. Characterization of a soluble oxidoreductase from the thermophilic bacterium Carboxydothermus ferrireducens. Extremophiles. 2009 Jul; 13(4):687-93. PMID: 19536454.
      Citations: 2     Fields:    Translation:AnimalsCells
    23. Onyenwoke RU, Kevbrin VV, Lysenko AM, Wiegel J. Thermoanaerobacter pseudethanolicus sp. nov., a thermophilic heterotrophic anaerobe from Yellowstone National Park. Int J Syst Evol Microbiol. 2007 Oct; 57(Pt 10):2191-2193. PMID: 17911280.
      Citations: 24     Fields:    Translation:Cells
    24. Onyenwoke RU, Wiegel J. Iron (III) reduction: A novel activity of the human NAD(P)H:oxidoreductase. Biochem Biophys Res Commun. 2007 Feb 09; 353(2):389-93. PMID: 17178108.
      Citations: 7     Fields:    Translation:HumansCells
    25. Sokolova T, Hanel J, Onyenwoke RU, Reysenbach AL, Banta A, Geyer R, Gonz?lez JM, Whitman WB, Wiegel J. Novel chemolithotrophic, thermophilic, anaerobic bacteria Thermolithobacter ferrireducens gen. nov., sp. nov. and Thermolithobacter carboxydivorans sp. nov. Extremophiles. 2007 Jan; 11(1):145-57. PMID: 17021657.
      Citations: 11     Fields:    Translation:CellsPHPublic Health
    26. Onyenwoke RU, Lee YJ, Dabrowski S, Ahring BK, Wiegel J. Reclassification of Thermoanaerobium acetigenum as Caldicellulosiruptor acetigenus comb. nov. and emendation of the genus description. Int J Syst Evol Microbiol. 2006 Jun; 56(Pt 6):1391-1395. PMID: 16738119.
      Citations: 12     Fields:    Translation:Cells
    27. Onyenwoke RU, Brill JA, Farahi K, Wiegel J. Sporulation genes in members of the low G+C Gram-type-positive phylogenetic branch ( Firmicutes). Arch Microbiol. 2004 Oct; 182(2-3):182-92. PMID: 15340788.
      Citations: 55     Fields:    Translation:Cells
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