Jayalakshmi Sridhar to Structure-Activity Relationship
This is a "connection" page, showing publications Jayalakshmi Sridhar has written about Structure-Activity Relationship.
Connection Strength
0.470
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Schroeder RL, Goyal N, Bratton M, Townley I, Pham NA, Tram P, Stone T, Geathers J, Nguyen K, Sridhar J. Identification of quinones as novel PIM1 kinase inhibitors. Bioorg Med Chem Lett. 2016 07 01; 26(13):3187-3191.
Score: 0.124
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Sridhar J, Sfondouris ME, Bratton MR, Nguyen TL, Townley I, Klein Stevens CL, Jones FE. Identification of quinones as HER2 inhibitors for the treatment of trastuzumab resistant breast cancer. Bioorg Med Chem Lett. 2014 Jan 01; 24(1):126-31.
Score: 0.105
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Sridhar J, Akula N, Sivanesan D, Narasimhan M, Rathinavelu A, Pattabiraman N. Identification of novel angiogenesis inhibitors. Bioorg Med Chem Lett. 2005 Sep 15; 15(18):4125-9.
Score: 0.060
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Sridhar J, Wei ZL, Nowak I, Lewin NE, Ayres JA, Pearce LV, Blumberg PM, Kozikowski AP. New bivalent PKC ligands linked by a carbon spacer: enhancement in binding affinity. J Med Chem. 2003 Sep 11; 46(19):4196-204.
Score: 0.052
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Zheng S, Zhong Q, Xi Y, Mottamal M, Zhang Q, Schroeder RL, Sridhar J, He L, McFerrin H, Wang G. Modification and biological evaluation of thiazole derivatives as novel inhibitors of metastatic cancer cell migration and invasion. J Med Chem. 2014 Aug 14; 57(15):6653-67.
Score: 0.027
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Liu J, Sridhar J, Foroozesh M. Cytochrome P450 family 1 inhibitors and structure-activity relationships. Molecules. 2013 Nov 25; 18(12):14470-95.
Score: 0.026
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Liu J, Taylor SF, Dupart PS, Arnold CL, Sridhar J, Jiang Q, Wang Y, Skripnikova EV, Zhao M, Foroozesh M. Pyranoflavones: a group of small-molecule probes for exploring the active site cavities of cytochrome P450 enzymes 1A1, 1A2, and 1B1. J Med Chem. 2013 May 23; 56(10):4082-92.
Score: 0.025
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Jiang Q, Payton-Stewart F, Elliott S, Driver J, Rhodes LV, Zhang Q, Zheng S, Bhatnagar D, Boue SM, Collins-Burow BM, Sridhar J, Stevens C, McLachlan JA, Wiese TE, Burow ME, Wang G. Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells. J Med Chem. 2010 Aug 26; 53(16):6153-63.
Score: 0.021
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Kozikowski AP, Gaisina IN, Petukhov PA, Sridhar J, King LT, Blond SY, Duka T, Rusnak M, Sidhu A. Highly potent and specific GSK-3beta inhibitors that block tau phosphorylation and decrease alpha-synuclein protein expression in a cellular model of Parkinson's disease. ChemMedChem. 2006 Feb; 1(2):256-66.
Score: 0.015
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Akula N, Bhalla J, Sridhar J, Pattabiraman N. Binding modes of 6,7 di-substituted 4-anilinoquinoline-3-carbonitriles to EGFR. Bioorg Med Chem Lett. 2004 Jul 05; 14(13):3397-400.
Score: 0.014