Receptor, Interferon alpha-beta
"Receptor, Interferon alpha-beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed heterodimeric receptor that is specific for both INTERFERON-ALPHA and INTERFERON-BETA. It is composed of two subunits referred to as IFNAR1 and IFNAR2. The IFNAR2 subunit is believed to serve as the ligand-binding chain; however both chains are required for signal transduction. The interferon alpha-beta receptor signals through the action of JANUS KINASES such as the TYK2 KINASE.
| Descriptor ID |
D053633
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| MeSH Number(s) |
D12.776.543.750.705.852.400.500
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| Concept/Terms |
Receptor, Interferon alpha-beta- Receptor, Interferon alpha-beta
- Receptor, Interferon alpha beta
- IFN-alphaR
- Interferon alpha Receptor
- alpha Receptor, Interferon
- Type I Interferon Receptor
- Interferon alpha-beta Receptor
- Interferon alpha beta Receptor
- Interferon alphabeta Receptors
- Receptors, Interferon alphabeta
- Receptor, Interferon alpha
- IFN-alphabetaR
- IFN alphabetaR
- Interferon alpha Receptors
- Receptors, Interferon alpha
- alpha Receptors, Interferon
Interferon alpha-beta Receptor Chain 2- Interferon alpha-beta Receptor Chain 2
- Interferon alpha beta Receptor Chain 2
- Interferon alpha-beta Receptor IFNAR2 Subunit
- Interferon alpha beta Receptor IFNAR2 Subunit
- Interferon alpha-beta Receptor-2
- Interferon alpha beta Receptor 2
- Receptor-2, Interferon alpha-beta
- alpha-beta Receptor-2, Interferon
- IFNAR2 Subunit, Interferon alpha-beta Receptor
- IFNAR2 Subunit, Interferon alpha beta Receptor
Interferon alpha-beta Receptor Chain 1- Interferon alpha-beta Receptor Chain 1
- Interferon alpha beta Receptor Chain 1
- Interferon alpha-beta Receptor IFNAR1 Subunit
- Interferon alpha beta Receptor IFNAR1 Subunit
- Interferon alpha-beta Receptor-1
- Interferon alpha beta Receptor 1
- Receptor-1, Interferon alpha-beta
- alpha-beta Receptor-1, Interferon
- IFNAR1 Subunit, Interferon alpha-beta Receptor
- IFNAR1 Subunit, Interferon alpha beta Receptor
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Below are MeSH descriptors whose meaning is more general than "Receptor, Interferon alpha-beta".
Below are MeSH descriptors whose meaning is more specific than "Receptor, Interferon alpha-beta".
This graph shows the total number of publications written about "Receptor, Interferon alpha-beta" by people in this website by year, and whether "Receptor, Interferon alpha-beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Interferon alpha-beta" by people in Profiles.
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Leung PY, Stevens SL, Packard AE, Lessov NS, Yang T, Conrad VK, van den Dungen NN, Simon RP, Stenzel-Poore MP. Toll-like receptor 7 preconditioning induces robust neuroprotection against stroke by a novel type I interferon-mediated mechanism. Stroke. 2012 May; 43(5):1383-9.
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Velichko S, Wagner TC, Turkson J, Jove R, Croze E. STAT3 activation by type I interferons is dependent on specific tyrosines located in the cytoplasmic domain of interferon receptor chain 2c. Activation of multiple STATS proceeds through the redundant usage of two tyrosine residues. J Biol Chem. 2002 Sep 20; 277(38):35635-41.