Inhibitor of Differentiation Protein 2
"Inhibitor of Differentiation Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negative regulator of BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS. It plays a role in regulating IMMUNOGLOBULIN E expression.
| Descriptor ID |
D051797
|
| MeSH Number(s) |
D12.776.930.329.500
|
| Concept/Terms |
Inhibitor of Differentiation Protein 2- Inhibitor of Differentiation Protein 2
- Inhibitor of DNA Binding 2 Protein
- DNA-Binding Protein Inhibitor ID-2
- DNA Binding Protein Inhibitor ID 2
- Inhibitor of Differentiation 2 Protein
|
Below are MeSH descriptors whose meaning is more general than "Inhibitor of Differentiation Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Inhibitor of Differentiation Protein 2".
This graph shows the total number of publications written about "Inhibitor of Differentiation Protein 2" by people in this website by year, and whether "Inhibitor of Differentiation Protein 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2008 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Inhibitor of Differentiation Protein 2" by people in Profiles.
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Sharma P, Chinaranagari S, Chaudhary J. Inhibitor of differentiation 4 (ID4) acts as an inhibitor of ID-1, -2 and -3 and promotes basic helix loop helix (bHLH) E47 DNA binding and transcriptional activity. Biochimie. 2015 May; 112:139-50.
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Sharma P, Patel D, Chaudhary J. Id1 and Id3 expression is associated with increasing grade of prostate cancer: Id3 preferentially regulates CDKN1B. Cancer Med. 2012 Oct; 1(2):187-97.
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Gray MJ, Dallas NA, Van Buren G, Xia L, Yang AD, Somcio RJ, Gaur P, Mangala LS, Vivas-Mejia PE, Fan F, Sanguino AM, Gallick GE, Lopez-Berestein G, Sood AK, Ellis LM. Therapeutic targeting of Id2 reduces growth of human colorectal carcinoma in the murine liver. Oncogene. 2008 Dec 04; 27(57):7192-200.
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Zhu X, Lin Y, Bacanamwo M, Chang L, Chai R, Massud I, Zhang J, Garcia-Barrio MT, Thompson WE, Chen YE. Interleukin-1 beta-induced Id2 gene expression is mediated by Egr-1 in vascular smooth muscle cells. Cardiovasc Res. 2007 Oct 01; 76(1):141-8.
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Chaudhary J, Schmidt M, Sadler-Riggleman I. Negative acting HLH proteins Id 1, Id 2, Id 3, and Id 4 are expressed in prostate epithelial cells. Prostate. 2005 Aug 01; 64(3):253-64.
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Chaudhary J, Sadler-Riggleman I, Ague JM, Skinner MK. The helix-loop-helix inhibitor of differentiation (ID) proteins induce post-mitotic terminally differentiated Sertoli cells to re-enter the cell cycle and proliferate. Biol Reprod. 2005 May; 72(5):1205-17.
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Magee TR, Qian A, Rajfer J, Sander FC, Levine LA, Gonzalez-Cadavid NF. Gene expression profiles in the Peyronie's disease plaque. Urology. 2002 Mar; 59(3):451-7.
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Chaudhary J, Johnson J, Kim G, Skinner MK. Hormonal regulation and differential actions of the helix-loop-helix transcriptional inhibitors of differentiation (Id1, Id2, Id3, and Id4) in Sertoli cells. Endocrinology. 2001 May; 142(5):1727-36.